ID SPAC821 standard; DNA; FUN; 35452 BP. XX AC AL121770; XX SV AL121770.1 XX DT 05-OCT-1999 (Rel. 61, Created) DT 11-JUN-2002 (Rel. 72, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c821. XX KW atpase.0; Cell division protein; Cu,Zn-superoxide dismutase; KW fungal Zn(2)-Cys(6) zinc-finger; G-beta repeat; KW gamma-glutamyl phosphate reductase; LTR; orb6; pseudogene; septin homolog; KW serine/threonine-protein kinase; slp1; sod1; spn2; U3 small nuclear RNA; KW WD domain; wd-domain protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-35452 RA Rieger M., Lyne M., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (05-OCT-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Genotype GmbH, Angelhofweg 39, D-69259 RL Wilhelmsfeld, Germany XX DR GOA; O13310; O13310. DR GOA; P28758; P28758. DR GOA; P78972; P78972. DR GOA; Q09116; Q09116. DR GOA; Q9HGK2; Q9HGK2. DR GOA; Q9UT43; Q9UT43. DR GOA; Q9UT44; Q9UT44. DR GOA; Q9UT46; Q9UT46. DR GOA; Q9UT49; Q9UT49. DR SPTREMBL; Q9UT43; Q9UT43. DR SPTREMBL; Q9UT44; Q9UT44. DR SPTREMBL; Q9UT45; Q9UT45. DR SPTREMBL; Q9UT46; Q9UT46. DR SPTREMBL; Q9UT48; Q9UT48. DR SPTREMBL; Q9UT50; Q9UT50. DR SPTREMBL; Q9UT51; Q9UT51. DR SWISS-PROT; O13310; ORB6_SCHPO. DR SWISS-PROT; P28758; SODC_SCHPO. DR SWISS-PROT; P78972; SLP1_SCHPO. DR SWISS-PROT; Q09116; SPN2_SCHPO. DR SWISS-PROT; Q9HGK2; ME13_SCHPO. DR SWISS-PROT; Q9UT49; CIDD_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c821 overlaps cosmid c222 at the 5' end XX FH Key Location/Qualifiers FH FT source 1..35452 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c821" FT /map="IL" FT misc_feature 1..3115 FT /note="nominal overlap with cosmid SPAC222, EM:AL132798 S. FT pombe chromosome 1" FT CDS join(445..493,540..593,641..742,785..925,1069..1373) FT /db_xref="GOA:Q9HGK2" FT /db_xref="SWISS-PROT:Q9HGK2" FT /note="SPAC222.15, len:216, SIMILARITY:Mus musculus, FT O35047, proteasome(prosome, macropain) 26s subunit, atpase FT 3, interacting protein(tbpip)., (217 aa), fasta scores: FT opt: 236, E():7.7e-07, (26.9% identity in 197 aa)" FT /note="originally annotated as a pseudogene because the FT third intron has a GAG acceptor, in 2 independently FT sequenced cosmids. But has Meiosis specific transcript FT disruption of which causes defect in meiosis. Personal FT communication Yasushi Hiraoka" FT /gene="meu13" FT /gene="SPAC821.01" FT /gene="SPAC222.15" FT /product="meiosis specific transcript; similar to S. FT cerevisiae HOP2; possibly required for pairing of FT homologous chromosomes in meiosis; meiotic expression FT upregulated; mutant displays decreased recombination" FT /protein_id="CAD33805.1" FT /translation="MAKAKEVKAKPIKGEEAEKLVYEYLRKTNRPYSATDVSANLKNVV FT SKQVAQKALEQLRDTGLIHGKLYGKQSVFVCLQDDLAAATPEELAEMEKQIQELKDEVS FT VVKTLYKEKCIELQALNNSLSPAEIREKIQSIDKEIEETSSKLESLRNGTVKQISKEAM FT QKTDKNYDFAKKGFSNRKKMFYDLWHLITDSLENPKQLWEKLGFETEGPIDLN" FT misc_feature 494..499 FT /note="gtataa, splice donor sequence" FT misc_feature 526..539 FT /note="ctaatcaatcgcag, splice branch and acceptor" FT misc_feature 594..599 FT /note="gtaaga, splice donor sequence" FT misc_feature 622..640 FT /note="ctgacaattttgttaaaag, splice branch and acceptor" FT misc_feature 743..748 FT /note="gtactg, splice donor sequence" FT misc_feature 770..784 FT /note="ctaacgattactgag, splice branch and acceptor" FT /note="this gene is flagged as pseudo, as acceptor which FT conserves homology is gag" FT misc_feature 1056..1068 FT /note="ctaactctaaaag, splice branch and acceptor" FT CDS join(complement(3680..3800),complement(3582..3634), FT complement(3364..3510),complement(3170..3268), FT complement(3025..3114),complement(2829..2975), FT complement(2415..2762)) FT /db_xref="SPTREMBL:Q9UT51" FT /note="SPAC821.02c, len:334" FT /gene="SPAC821.02c" FT /gene="csn3" FT /gene="SPAC222.16c" FT /product="COP9/signalosome complex subunit 3; no apparent FT S. cerevisiae ortholog" FT /protein_id="CAB57436.1" FT /translation="MEFQGTLPFHPLEDPETLLLKFTDFVHQHSVEQCNQLSMYIIASV FT NSLAEAFYGSHPEKYNIVFQSVEYAAHSPAISVMHVCYLKELLRQGQYATSLKSFNDLE FT VSKHIPGSILLQYCMYAAYHCLGNNDLDSAKVWYFSILYIPTTTLTSFHEEAYYSFLLL FT YIITTGKKFQLDSATSSNVLPLKRHMVPYEEFLDAYLKDVNTLRTVIKEHWSRFLKDNS FT TAFILFALEVYPMHRLKKWRKTFSSLKLEYIAKQLAISQDVAKEIIQKFDNKTNFTVAN FT GEIFLTFNALDDVSPEMHSDLCQQLIEASKNFEASIRLKSVIYSKIMAKKLNA" FT misc_feature complement(2763..2780) FT /note="ctaaccatcttgaattag, splice branch and acceptor" FT misc_feature complement(2823..2828) FT /note="gttggt, splice donor sequence" FT misc_feature complement(2976..2993) FT /note="ctaattctttcgattcag, splice branch and acceptor" FT misc_feature complement(3019..3024) FT /note="gtatct, splice donor sequence" FT misc_feature complement(3115..3130) FT /note="ctaatgcgttaattag, splice branch and acceptor" FT misc_feature complement(3164..3169) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(3269..3281) FT /note="ctaaccaattcag, splice branch and acceptor" FT misc_feature complement(3358..3363) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(3511..3523) FT /note="ctaactaaaaaag, splice branch and acceptor" FT misc_feature complement(3576..3581) FT /note="gtaggt, splice donor sequence" FT misc_feature complement(3635..3647) FT /note="ctaacttgtttag, splice branch and acceptor" FT misc_feature complement(3674..3679) FT /note="gtatgt, splice donor sequence" FT CDS complement(4534..5991) FT /db_xref="SPTREMBL:Q9UT50" FT /note="SPAC821.03c, len:485" FT /gene="SPAC821.03c" FT /product="hypothetical serine-rich protein; sequence FT orphan" FT /protein_id="CAB57437.1" FT /translation="MSSIIQNPIESSYFVEDLSAVGNSQLHSGRSLTYGDRKANIDTRS FT GGGRRFWSNLNDSGNSFGAVPASSMNLSYGPTKSATISSKDGAMSRSSRYYVSSELKAT FT LPSLDGRRLSKRNAANHASHHRMPDESASYRTRGEYESSSPRVPQKSLRRYYSTRTAQR FT LDVRRPASRSSRYSKTSDLPPSDPGRFVDDSDLTPHTDFTNRFVDSDFDPDSGVGRSSS FT PDQMMSRNNNLNINARMTSTSSKPYAKENQQLISSMAPVEQKNSFSTAREQYVAPALSF FT AEPVETQHNHMPKTTPLRGTSTVMNGSPIGPYSSSSNATGMYGVSKGHSSSTRRPFFSD FT VGSSQPAEEFVGSSSSHGRQQDSYIADDSDSERSYRRVRDQYLSKPRLSDKNRYSTFSE FT FPGQGTPSASQSNLRRSNTVRPTSFYYEKLHIKNDNPSFQALPYETTTQERKPVVKPDS FT IKTVKPEKKKSKGFFKKLMHKISHIFD" FT CDS complement(7747..9483) FT /db_xref="GOA:Q9UT49" FT /db_xref="SWISS-PROT:Q9UT49" FT /note="SPAC821.04c, len:578, SIMILARITY:Schizosaccharomyces FT pombe, O74326, hypothetical 54.5 kD protein., (478 aa), FT fasta scores: opt: 970, E():0, (38.7% identity in 429 aa)" FT /gene="SPAC821.04c" FT /function="non-essential" FT /gene="cid13" FT /product="cid1-related; putative nucleotidyl transferase" FT /protein_id="CAB57438.1" FT /translation="MDNANCVGGCKFETRSFQYRRRIPYSLGADPLPPVHPLSLKNLVD FT IDTDLISSQLYELYDSIILNDSGLERRYAFVQKLEQILKKEFPYKNIKTSLFGSTQSLL FT ASNASDIDLCIITDPPQCAPTTCEVSAAFARNGLKKVVCISTAKVPIVKVWDSELQLSC FT DCNINKTISTLNTRLMRSYVLCDPRVRPLIVMIKYWAKRRCLNDAAEGGTLTSYTISCM FT VINFLQKRDPPILPSLQMLPHLQDSSTMTDGLDVSFFDDPDLVHGFGDKNEESLGILFV FT EFFRFFGYLFDYEHFVLSIRHGTFLSKRAKGWQFQLNNFLCVEEPFHTSRNLANTADEI FT TMKGIQLEFRRVFRLLAYNCNVDDACSQFTFPSLTDTSFMDDYVNELQLEIVPGFSHGR FT DSSDTSCTESPPEPSHFAWAFDPYNATASPYYNQNINSSIDYSSIYSNDVPAIPPNVPY FT TFVDPYTYACYINNNSYLPPSYMDFYTWYNSPYPKSSHHFDERHGGDRHEKNLSNSRRY FT SRNKFHKKKQSSGPFQYYPDAFSFTPTDNNSPPSNSSSSEVVSPVSLHSEPVLSTVQAF FT KS" FT snRNA complement(10367..11002) FT /note="U3 small nuclear RNA" FT /gene="U3snRNA" FT CDS join(11133..11158,11198..11304,11484..12424) FT /db_xref="SPTREMBL:Q9UT48" FT /note="SPAC821.05, len:357, SIMILARITY:Drosophila FT melanogaster, AAD46836, bcDNA.gm14618., (309 aa), fasta FT scores: opt: 234, E():4.3e-08, (25.4% identity in 323 aa)" FT /gene="SPAC821.05" FT /product="putative eIF3 p40 eIF/signalosome component; MOV FT domain; no apparent S. cerevisiae ortholog" FT /protein_id="CAB57439.1" FT /translation="MSDTTSLNVPELESPPIERVELESLLVMNIIKHCRDSFPNMGTIG FT QLVGIDIDGVLQVSSSFESPSVLENEESAVNKSVSGKARQAHTEAMLNRLQYIGAVTGH FT VGWYLGAYVSSFLSSPFFVETQYAYQKANPNSIAFLYDLSQSSNGTLYMRAYQLTPEFM FT AAHEEKTWTASSLNSHNLTPSNVIRELPIVIHNSHLATCLLHSLSEPPTPASTLTAEAA FT LEDCESNLPLTETFSNFEVSLGTRYRKNIELLLESTDEFHYEQGNLGFHQRQLAREQAK FT IQQWIAKRKAENANRAAENLQPLPLDDWKRIFKLPAEPRLLDSLLISSQIMKSTQIDEQ FT SSAFLSKLAGVRNAYAS" FT misc_feature 11159..11164 FT /note="gtaaga, splice donor sequence" FT misc_feature 11186..11197 FT /note="ctaattcagtag, splice branch and acceptor" FT misc_feature 11305..11310 FT /note="gtaagt, splice donor sequence" FT misc_feature 11469..11483 FT /note="ctaactttcgttcag, splice branch and acceptor" FT CDS join(12986..13025,13075..13149,13208..13336,13448..13529, FT 13592..14261) FT /db_xref="GOA:Q09116" FT /db_xref="SWISS-PROT:Q09116" FT /note="SPAC821.06, len:331" FT /gene="spn2" FT /gene="SPAC821.06" FT /product="septin homolog" FT /protein_id="CAB57440.1" FT /translation="MEVPSAVTLNNYVGFDSITSQINRKLIRRGFQFNVMVVGPSGSGK FT STLINTLFSAHLMDSKGRLDYQAPYRQTTEIHVTSQVVRENRVQLQLNLIDTPGYGDQI FT NNDKCWEPIIKYIRDQHSSYLRRELNSHREKRLQDTRVHCCLFFIRPTGHSLRPIDIAV FT LKRLTEVVNVVPVIAKSDSLTLEERAAFKQQIREEFVKHDINLYPYDSDDADEEEINLN FT AAVRNLIPFAVVGSEKAIIVDGRPIRGRQNRWGVVNVDDENHCEFVFLRNFLMRTHLQD FT LIETTSYYHYEKFRFKQLSSLKEQSSLATRMGSPAPVYPSEPHLHTATAQ" FT misc_feature 13026..13031 FT /note="gtatga, splice donor sequence" FT intron 13026..13074 FT /note="Confirmed Intron" FT misc_feature 13062..13074 FT /note="ctaatgtttatag, splice branch and acceptor" FT misc_feature join(13119..13149,13208..13336,13448..13529,13592..14177) FT /note="Match to PF00735 GTP_CDC, cell division protein FT Score 479.36" FT misc_feature 13150..13155 FT /note="gtacgt, splice donor sequence" FT intron 13150..13207 FT /note="Confirmed Intron" FT misc_feature 13191..13207 FT /note="ttaacagtttcaaatag, splice branch and acceptor" FT misc_feature 13337..13342 FT /note="gtatgt, splice donor sequence" FT intron 13337..13447 FT /note="Confirmed Intron" FT misc_feature 13436..13447 FT /note="ctaaccacatag, splice branch and acceptor" FT misc_feature 13530..13535 FT /note="gtaagt, splice donor sequence" FT intron 13530..13591 FT /note="Confirmed Intron" FT misc_feature 13579..13591 FT /note="ctaactataatag, splice branch and acceptor" FT CDS complement(14488..15981) FT /db_xref="GOA:Q9UT46" FT /db_xref="SPTREMBL:Q9UT46" FT /note="SPAC821.07c, len:497, SIMILARITY:Nectria FT haematococca., Q00881, negative acting factor, (455 aa), FT fasta scores: opt: 268, E():9.4e-09, (32.9% identity in 173 FT aa)" FT /gene="SPAC821.07c" FT /product="putative transcriptional regulator; zinc finger FT protein; fungal Zn(2)-Cys(6) binuclear cluster domain; FT subcellular localization of GFP fusion-Nucleus" FT /protein_id="CAB57441.1" FT /translation="MKRNRTGSINSNPLYIPNPNVEPTPKPTKRRTKTGCLTCRRRRIK FT CDETKPFCLNCTKTNRECEGYPNSAAQMQAMGSVSPPELSVHSAQQPLIPTSIASSSAQ FT TGDTFSGSSQSNFNTNDLNQMTSSSNLSTVTPIKQDHQKPMNLQGFPSAYQQHQYLQSN FT HNVPTNNSSSATSSTKPSVQSVGQASYPFLSSVSNFPSNFNSELFPFYFHDVVPSICAF FT EFDNNIALHFWSVTVPQFAQSMPCIANSLMAFASIKKLDVFGAYSHLTRALRCPMPGPN FT SFEYLLVSAFLTLTQLNLPAYDLNFCNNFIRKLSWSSSTKSNYVSLLIAMVVRELVFAI FT LPRGCIWGFNGKPLSEVSVSRSHAPVSDSLFTIGLDILSQPTLSDDLHRERMVAWRDEY FT HVHLYSASRSPLTKVIDCVGHAVTKNNNDVLSGLQQLMQEECTDIAVLRTSYLCVLSLQ FT NVFASNSKEFKLRAQIESHFGRLMLEHFMDCNVLNRPVL" FT misc_feature complement(15775..15882) FT /note="Match to PF00172 Zn_clus, fungal Zn(2)-Cys(6) FT binuclear cluster domain Score 53.12" FT CDS complement(18212..19678) FT /db_xref="GOA:P78972" FT /db_xref="SWISS-PROT:P78972" FT /note="SPAC821.08c, len:488" FT /gene="slp1" FT /gene="SPAC821.08c" FT /product="WD repeat protein; spindle assembly checkpoint FT protein; interacts with Mad2p; APC activator (fizzy); FT similar to S. cerevisiae CDC20" FT /protein_id="CAB57442.1" FT /translation="MEIAGNSSTISPTFSTPTKKRNLVFPNSPITPLHQQALLGRNGRS FT SKRCSPKSSFIRNSPKIDVVNTDWSIPLCGSPRNKSRPASRSDRFIPSRPNTANAFVNS FT ISSDVPFDYSESVAEACGFDLNTRVLAFKLDAPEAKKPVDLRTQHNRPQRPVVTPAKRR FT FNTTPERVLDAPGIIDDYYLNLLDWSNLNVVAVALERNVYVWNADSGSVSALAETDEST FT YVASVKWSHDGSFLSVGLGNGLVDIYDVESQTKLRTMAGHQARVGCLSWNRHVLSSGSR FT SGAIHHHDVRIANHQIGTLQGHSSEVCGLAWRSDGLQLASGGNDNVVQIWDARSSIPKF FT TKTNHNAAVKAVAWCPWQSNLLATGGGTMDKQIHFWNAATGARVNTVDAGSQVTSLIWS FT PHSKEIMSTHGFPDNNLSIWSYSSSGLTKQVDIPAHDTRVLYSALSPDGRILSTAASDE FT NLKFWRVYDGDHVKRPIPITKTPSSSITIR" FT misc_feature complement(18683..18787) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 40.18" FT CDS 21689..24739 FT /db_xref="SPTREMBL:Q9UT45" FT /note="SPAC821.09, len:1016, SIMILARITY:Schizosaccharomyces FT pombe, YAEA_SCHPO, hypothetical 77.9 kD protein c23d3.10c FT in chromosome i, (706 aa), fasta scores: opt: 1525, E():0, FT (41.3% identity in 700 aa)" FT /gene="SPAC821.09" FT /gene="eng1" FT /product="endo-1,3-beta-glucanase" FT /protein_id="CAB57443.1" FT /translation="MSSYLRSFIFGLLTISLAQCSPILKDTKDTKFSTGSNISLKKRDT FT NVFDSVVDTINPASYFGTVSHPVTPAGVSTDSLSSPIETNKFFDNNLLGSRTNFMYADP FT FRYWWQSSDTMGGICIAHTDDNQRVMDTDDTIPSYYYEPIGICSLGFGASGITSNTDPI FT VDEIDQMSARFTFSWDSSSMQLTLTEGMAVTTAVYTNAIPQIFSSTLYINDFVEVPGTS FT AVQKYRVTMSDNHVWLIYIYGDSLTLTESTSQMLVGSNTFNGYIQIAKIPLGDGTAEAL FT YDTYAGVYITGISISGYVEDAVGYYSFDFTTAGDTSVEPLFFLLPHQVDTAVSGTKVTS FT IVLASLVSGDMNAAAGNSITFAEAIPQDIGFLPWSPTGGQIGYSEEALEIIAEVAGTEL FT GEDFSANSNLNSMYYSGKVLAKYAMLCVTINDILGDETSSEQCIQKLEAAFARFVDNQQ FT IYPLTYDNTWKGVVSVAGLSGDSLADFGNSYYNDHHFHYGYFVFTAAVIGHIDPDWINT FT GNNKEWVNFLVRDVANPSSNDPYFPKHRMIDIYHGHGWASGLFESNDGKDEESTSEDYN FT FFFGMKLWGQVIGDSDMEDRANIILGIERNALNKYMLYADGNVQPTSMQPNYVAGITFM FT NKITHTTYFGTNIEYIQGIHMLPITPISAFIRGPSFVLAEWNALLASVIDYVDSGWRSL FT LYANLAIAEPEESYEYFSSSDFNTDYLDDGASRAWYLAYAAGLWANDAVYYPVSSSSTT FT TTSTSTGSVTTTSTTATASCTLPISYTSTPTTTSISGTCNGATFDASLYVCDGTVLCPI FT VNGVSYQNCNGACYNPSQYGCDNGALGPVQSSSTTSSITPTPTTTSSITPTPTTTSTTT FT TAQSTGMQLCGSNYYDASSYYCDNDQLCPIIDGVDYLSCNGACYNPSQYVCSDGSLSPN FT TVTTTKATTTFTPTPTTTTTPTPTTTSATSTNVIAQCGSAWYDSQSYICYGNILCPIIN FT GSPLLACGNACYDSSIYGCSNGALVAA" FT CDS complement(25735..26199) FT /db_xref="GOA:P28758" FT /db_xref="SWISS-PROT:P28758" FT /note="SPAC821.10c, len:154" FT /gene="sod1" FT /gene="SPAC821.10c" FT /product="Cu,Zn-superoxide dismutase" FT /EC_number="1.15.1.1" FT /protein_id="CAB57444.1" FT /translation="MVRAVAVLRGDSKVSGVVTFEQVDQNSQVSVIVDLVGNDANAKRG FT FHIHQFGDNTNGCTSAGPHFNPEGKTHGDRTAAVRHVGDLGNLESDAQGNIKTTFSDSV FT ISLFGANSIIGRTIVIHAGEDDLGKGTSEESLKTGNAGARNACGVIGIAV" FT misc_feature complement(25741..26199) FT /note="Match to PF00080 sodcu, Copper/zinc superoxide FT dismutase (SODC) Score 351.21" FT LTR 27628..27985 FT /note="TF1-type lone LTR" FT CDS 29130..30485 FT /db_xref="GOA:Q9UT44" FT /db_xref="SPTREMBL:Q9UT44" FT /note="SPAC821.11, len:451, SIMILARITY:Synechocystis sp., FT PROA_SYNY3, putative gamma-glutamyl phosphate reductase, FT (433 aa), fasta scores: opt: 1302, E():0, (48.9% identity FT in 436 aa)" FT /gene="SPAC821.11" FT /EC_number="1.2.1.41" FT /gene="pro1" FT /product="putative gamma-glutamyl phosphate reductase" FT /protein_id="CAB57445.1" FT /translation="MSLEENVKEAKNAFNILQTLSVEDRDDALDKIVEELRIKKSEVLA FT ANAEDMKAAKLLAESGKLSSSMVKRLDLSSSDKYDSMVQGVLDVKSLPDPLGRVTYARS FT LDDGLDLYKVSCPVGLLLVIFEARPEVIINITSLAIKSGNAVVLKGGTESAKSFAALSN FT VVRSALGKSKVPQAAVQLVQSREEVSQLLKLDEYIDLVIPRGSTNLVRHIKDNTKIPVL FT GHAAGLCSMYVHEDADMELASKLVLDGKTDYPAACNAIETLLINEAVLSSHLPKIAETL FT TEAKVTLKCDPASLKVLKDMPKVSALVEPSVDQDYNTEFSDLILAIKTVPSLQSAMQHI FT NTHGSKHTDCIITSSEAAANRFMAGIDASGVYWNASTRFADGFRYGYGTEVGISTNKIH FT ARGPMGLDGLTIYKYQLRGNGQVASSYGVGPGKRAFKHTPINIDNISQVSKK" FT misc_feature 29298..29924 FT /note="Match to PF00696 aakinase, Aspartate kinases, FT Glutamate kinases and Gamma glutamate phospho-reductases FT Score 193.73" FT CDS join(31175..31317,31585..31759,31805..32896) FT /db_xref="GOA:O13310" FT /db_xref="SWISS-PROT:O13310" FT /note="SPAC821.12, len:469" FT /gene="orb6" FT /gene="SPAC821.12" FT /EC_number="2.7.1.37" FT /product="serine/threonine protein kinase; involved in cell FT polarity maintenance" FT /protein_id="CAB57446.1" FT /translation="MDKNDYLHFERNPSLFPKSTLDKVQKTKKYIEHYYKVAVDHAVER FT NQRRINLEQRLATERGSEERKNRQLRASGEKESQFLRFRRTRLSLEDFSTIKVIGKGAF FT GEVRLVQKLDTGKIYAMKSLLKTEMFKRDQLAHVKAERDLLVESDSPWVVSLYYAFQDS FT LYLYLIMEFLPGGDLMTMLINYDTFSEDVTRFYMAECVLAIADVHRMGYIHRDIKPDNI FT LIDRDGHIKLSDFGLSTGFYKQDQSASYMKPRTGNTVKRGQMVDAIWLTMSSKDKMATW FT KKNRRVMAYSTVGTPDYIAPEIFLQQGYGQDCDWWSLGAIMFECLIGWPPFCSENSHET FT YRKIINWRETLTFPNDIHLSIEARDLMDRLMTDSEHRLGRGGAIEIMQHPFFTGIDWDH FT IRETAAPFIPNLKSITDTHYFPVDELEQVPEQPVTQQPASVDPQTLEQTNLAFLGYTYK FT KFNYLTMKGAL" FT misc_feature 31318..31323 FT /note="gtacga, splice donor sequence" FT misc_feature 31571..31584 FT /note="ctaattctctttag, splice branch and acceptor" FT misc_feature 31760..31765 FT /note="gtacgt, splice donor sequence" FT misc_feature 31793..31804 FT /note="ctaattaaatag, splice branch and acceptor" FT misc_feature 31805..32662 FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 201.08" FT CDS complement(33376..35452) FT /codon_start=2 FT /db_xref="GOA:Q9UT43" FT /db_xref="SPTREMBL:Q9UT43" FT /note="SPAC821.13c, len:617, SIMILARITY:Arabidopsis FT thaliana, AAD39325, putative atpase., (1123 aa), fasta FT scores: opt: 1134, E():0, (37.6% identity in 529 aa)" FT /partial FT /gene="SPAC821.13c" FT /gene="SPAC955.01c" FT /product="P-type ATPase (P4 type) (pers comm A. L. FT Okorokova Facanha); putative aminophospholipid translocase FT (pers comm A. L. Okorokova Facanha); similar to S. FT cerevisiae YMR162C" FT /protein_id="CAB57447.1" FT /translation="IIKRLRLSNLAKRKDKSVTKAEQARKSIEIDKAIIRNSQSTSRPS FT LTASRPSLSRRRNDYINNVTSWLDERREKMGVVRPRASTSILETRRRPAVGRHSLAGGE FT RLMEDKKYLSKQEEAEGSIYESLNHNDAKLFENTFEHVHAFATDGLRTLMYAHRFIDES FT EYQSWKLVNDAALNSLSNRQQLLDEAADLIEKDLEFAGATAIEDKLQVGVPESINSLFR FT AGIKFWMLTGDKKETAINIGHSCGVIKEYSTVVVMGSLDGVEGSDETVSGGQRLSLDRP FT PTNDPASLMIHQLISCMNAIHSNSLAHLVIVIDGSTLADIENDPELFLLFINTAVEADS FT VICCRSSPMQKALMVQKVRNTLEKAVTLAIGDGANDIAMIQEAHVGIGIAGREGLQAAR FT SSDFSIGRFKFLIKLLFCHGRWSYVRLSKYILGTFYKEQFFFLMQAIMQPFVGYTGQSL FT YESWGLTCFNTLFSSLCVIGLGIFEKDLSASTVIAVPELYQKGINNEAFNWRVYFGWCS FT IAFIQAFLVFYVTYSLFGMKELNDNNIFAYGQLIFTAAIFIMNFKLVFIEMQYINIISI FT IVLVLTSLAWFLFNIFISEHYPDKNLYLARSQFLHHFGKNPSWWLTMLFVMVCALTIDI FT VAQMLRRTLRPTDTDIFVEMENDAFVRSRFEQESGEFLQANAPSVDEIEQYLKSRD" FT misc_feature complement(34702..34875) FT /note="Match to PF00122 E1-E2_ATPase, E1-E2 ATPases Score FT 24.32" XX SQ Sequence 35452 BP; 11537 A; 6435 C; 6484 G; 10996 T; 0 other; ttaaacgttt ctcaaaagcg cttcgtagta ttcgacgata tcggtttcat tcaatttgtg 60 aagtgttttt gacgttgccg aatatgctaa aaaagtacaa acatactata atatagccct 120 tcgcaaggtt ggaaattatt taatttaata aaatttctag catagcttta ggaatcgaat 180 tctttgtact aatgtctcac tatcctatgc aaccttcttt cattgacacg atgcgcaatt 240 caacccatcg ttatgagtac tttatatagg tgcgtaaaat agttaaaatc ctttctcatg 300 gattttcttc cttagtttag ctaagaacaa aggagaatgg cttggggaaa acgcgttgtc 360 tccgccacgc gtaaatatta tatataaatg tttgatgcta catcgcgctt ttactatttt 420 cctcacacat cgcaattgta gcaaatggct aaggcgaaag aagtaaaagc gaaacctatt 480 aaaggagagg aaggtataat attgacaaaa ggcattggta ttcagctaat caatcgcagc 540 tgaaaaactt gtttacgagt atttacgaaa aacgaatcgt ccctattctg caagtaagaa 600 catacattaa aaaaatcgaa gctgacaatt ttgttaaaag ctgacgttag tgctaatttg 660 aaaaatgttg tcagtaaaca ggtcgcgcag aaagcattgg agcagctacg cgacactgga 720 ctaatccatg ggaaactata tggtactgaa aaattagtta aacagattac taacgattac 780 tgaggaaaac aaagtgtgtt cgtttgtctt caagatgact tggcagctgc tactcctgaa 840 gaattggctg aaatggagaa gcaaattcaa gaactaaaag atgaggtttc agttgttaaa 900 actctataca aagagaaatg cattggtcag taaataaatg ctattcttta aaatgtagaa 960 tgatacttca cataatatgc atgatttaaa acagatcaaa gttttattga tggtatcgtt 1020 catttgtttt gagcgtacac agcacttgtt ttatgctaac tctaaaagaa ttacaagctt 1080 taaataactc actcagtcca gccgaaattc gtgaaaaaat tcagagcatt gataaagaaa 1140 ttgaagaaac cagctcaaaa ctcgaatctc ttcgaaatgg taccgttaaa caaatttcca 1200 aggaagcaat gcaaaagact gataaaaact acgattttgc aaaaaaagga ttctcaaaca 1260 gaaagaaaat gttttatgat ttatggcatt taattactga ttccttggaa aaccctaagc 1320 agttatggga aaaactggga tttgaaacgg agggaccaat tgacttaaac taaaaactta 1380 actttaaatt tagctgatcc ctttttaaca ttttaatcat taaatttata tagctcaaag 1440 aaaagtcatt atccatagtt aaatataaat accttagcag acaactgctc taatatgtgc 1500 ttgcattgct gcacaacatt acctgtcctc ttgctatact gtgtggttat gactagtgct 1560 tcttacgtcg tgatagcttt gattttttgg ttaaagtaga aagcctagtg aaagcattag 1620 attttgcaat ttaagctaat gtctaatgca ccatcaaata cgccaacagg gtttaattat 1680 aaacctgggc atactttgta tattcgaaat ttcggaacgg atatgagagc ccggacacta 1740 ggccaggcct ttgaaaagta attgttattg aatgactgat tgtagattac aactttggtt 1800 ttcagtcaag tgatctctat ttttgtatcg catctgttct aattgatgat aatagatggg 1860 gtagaatagt tcggtgtgat attcccattt caagtaaccc tcaagctcat cggtatgctt 1920 tattaatttg caaattatta acacttctag gtatgctttc gtggaatttg aagagcgaga 1980 gaaagctgag ttggcgcacg aaaaaatgcg taatgccaaa attggaaacg atattatttt 2040 tgtagaatgg gcgaaaagta gagaaagata tcaccgagat gacaaaagga gattaagtaa 2100 ttacgcctga agaagagggt ttactacaag agtatgcaat atgctaagtt cgagtgcaat 2160 tgaccacgaa aataatgatc gatcgctttt ttagatttat gttttttttt attctttaaa 2220 attttgcttt ctataattag atgaatctgt aagctaagtt ttaactatca ctccaacacc 2280 tgcatcggtg agccataggt gtaagaattt cattaattga attttaagac ttgttgagaa 2340 tttggtatat ttccacaaac attattaatt ttataaccac ttttagagat tactaaatgt 2400 aattaatttt gtagctacgc gttgagcttt tttgccatta ttttagaata aataacggac 2460 ttcagtcgaa tggaagcttc aaagtttttc gatgcttcaa ttagttgctg acacaaatca 2520 gaatgcattt ctggcgaaac atcatccaaa gcattgaagg tcaaaaatat ttctccgttt 2580 gctactgtaa aatttgtttt gttgtcaaac ttctgaataa tttcttttgc aacatcttga 2640 gatattgcca gttgttttgc gatgtattcc aactttaagg aagaaaatgt ttttctccat 2700 tttttaagcc ggtgcatagg ataaacctcc aatgcaaaga gaataaaagc cgtagaattg 2760 tcctaattca agatggttag cattcatctt catttcgtaa atttaaactt tcattcgcct 2820 taaccaacct ttaaaaaacg cgaccagtgc tccttaataa cagtacgtaa agtattaaca 2880 tctttaagat aagcatctaa aaattcttcg taagggacca tatgtctttt taatggtaaa 2940 acattactgg atgtagcaga atccaactga aatttctgaa tcgaaagaat tagtacttgt 3000 gatttttcaa gggaaaaaag atacctttcc agttgttata atatataaca gcagaaaact 3060 ataataagcc tcctcatgga aggaggttaa agtagtggta ggaatataca ggatctaatt 3120 aacgcattag aaatgtatag gtcatttgaa tccaaaataa ttgacttaca gaaaaatacc 3180 aaacttttgc agaatccaag tcattatttc ccagacaatg gtatgctgca tacatgcagt 3240 actgcaataa aatggatcca ggtatatgct gaattggtta gcgtcacctc cactttgaag 3300 ttataagaga aaatattctg atatacttga aatttcgagt attaaaggta atagtacact 3360 tacttttgat acttcaagat cattaaaaga tttaagagat gtagcatatt gaccttgtct 3420 aagtaactcc tttaaatagc acacatgcat tactgatatg gcaggagaat gggcagcata 3480 ttcgaccgat tgaaaaacta tgttatattt cttttttagt tagcttattt cattaagcaa 3540 aaatagccgt cgagaatggg gcatctcgag tattaaccta cctcagggtg actaccgtag 3600 aacgcctctg ccaaagaatt tactgaggca ataactaaac aagttagatt ttaaaacgag 3660 cttgatctag ttaacatact atacatgctt agctgattgc attgttccac tgaatgttga 3720 tgtacgaaat ctgtgaactt caatagcaat gtttcaggat cctctaacgg atgaaatggt 3780 aaagttcctt gaaattccat attggcaacc attcatgaat catttatgga taagacaaat 3840 actctcaaaa atcgtttgta atgtttaggt atatgaattt ccttcctcta atgatttaat 3900 gattactacc gcgctcgctg tattgtgatg gtataatttc acattttggg tacttacgac 3960 cataaagttg tcgtgatgtt aatacagcat tagctttaaa cttttcgtaa taaaaagatt 4020 ttatctatcc agcgcatcat tctattctat ataataatca gtccctaacg aatagtagct 4080 tacaattgcg tccaagaagt atgagctagt aaatagtaaa caatttgaag atactgttta 4140 acaacgttac aaatgggtat aaaagcaatc aagtgctaat agtatgttgc ttgtcgtagt 4200 attacaaatt ctatatgcaa agggaagaaa aatcaatttc tacggtaact atgaataatt 4260 aataaattat atggaaagcc agcttttaaa caaaaattag caaaccgtac agtttaaaca 4320 ctgtaaaaac ccattttata attttaattt tttaactaca agataatcga cgcattaact 4380 atttatccga attagacgaa aaaaagatat agagcatata tacatagata tatacatata 4440 agggcaaaag agcgtatatg gattgggttg atgtaaaaac tggcttagta gcaaggaaga 4500 taaacgacga aaaaaatata acagcagaaa catttaatca aaaatgtgag aaattttgtg 4560 catcagcttt ttaaagaaac ctttagattt cttcttttct ggtttcacag ttttaataga 4620 atcaggctta actacgggct ttcgttcttg agtagtagtt tcatatggca aagcttgaaa 4680 actgggatta tcattcttaa tatgaagctt ttcgtagtaa aagcttgttg gacgaacagt 4740 attcgacctt ctcaaattcg attgtgaagc acttggagta ccttggcctg gaaactctga 4800 aaatgtacta taacgatttt tatcggataa gcgaggtttc gacaagtatt gatcgcgaac 4860 acgcctgtaa ctccgttctg aatcagaatc gtctgctata tacgagtcct gctgacgacc 4920 atgactggag gaagatccga caaattcctc ggcaggttgt gatgaaccaa catcggaaaa 4980 aaaaggacga cgagtagatg aactatgacc ttttgaaaca ccatacatcc cagtggcatt 5040 gcttgaagaa gaataaggac caataggaga accattcata acagtagagg tacctctgag 5100 aggagttgtt tttggcatat gattgtgttg ggtttcaaca ggttcagcga atgacagggc 5160 tggcgcgaca tattgctcgc gagccgttga aaatgaattt ttttgctcta ctggagccat 5220 ggaggaaatt agttgttgat tctccttggc ataaggttta gaggaagtac tagtcatgcg 5280 ggcattgatg ttaagattat tgttcctcga catcatttga tcaggggagg aagaacggcc 5340 tactcctgaa tcaggatcga aatcggaatc cacaaatcga ttagtaaagt ctgtgtgggg 5400 agtcaaatcg ctatcgtcca caaatctccc cgggtcagaa ggtggaagat cgcttgtttt 5460 gctgtatcga ctcgatcgcg atgcgggacg tcgaacgtcc aaacgttgag cagtacgagt 5520 tgagtagtaa cgccttaaag atttttgagg tactcgagga gagctacttt catactcccc 5580 acgtgtgcga tagctagctg actcatcggg catgcgatga tgcgaagcat gattagcagc 5640 gtttcgtttg ctcaaacgac gtccatctag agaagggagg gtagccttta attctgatga 5700 gacataataa cgactactgc gagacatcgc tccatctttc gaggaaatag ttgcgctttt 5760 cgttggtccg taacttaaat tcatagagga agccggtact gcgccaaaac tgttccctga 5820 atcgtttaaa ttactccaaa atcttcttcc tccaccactt ctagtgtcta tgtttgcttt 5880 tcgatcgccg taagtaagtg accgaccact gtgaagttga ctatttccaa ccgccgataa 5940 atcttccaca aagtatgaag attcaattgg attttggatt atagagctca ttcaagtaaa 6000 tacacgcaaa ctgttttcac ctgaacccta ttactctcta aagttcgata agcagcgttt 6060 gccgtttttg aaaaattccc ccttttattc cgaacaacct caaatttatg ttacaatacc 6120 tcttgagcta ttcgaatatg aacgtttttc gagtttcctt taaattctca aaaaacccca 6180 atttttcact caatccgctc tcaaattttc aatcttcgag ttcaaggaag agcaaaacaa 6240 cttagtgagt gaattcacct tgcgtactac ggtatactga gtgacatcat caatgcggat 6300 aaccgcatta aatatcgaac ggtgttgatc atgcttacct cttgttaatc cgcaaaaagc 6360 tatactatgc tatttaacac tattgagctt aacccatttt accttaaaac tatcgttaaa 6420 aaagttaggc aagtcatgta aaattaaaga tatgcaaatt gatttaatgc aatgcatcaa 6480 actcttcaat aaaaatttac agagctttag gtaaactaaa gtaaatccat caacactgtg 6540 aagtgtgatg gatatgtgaa aaaacaacgg taacaaggca acgtagtaaa taaagattta 6600 ttcaatcaat caaactatca tttcagcagg ggagagatat ttaaaaaaaa aaataaaaaa 6660 aaacattttc ccatgctgta caactcatac cagtgctttg ttcgcactca cattaatggg 6720 ttgatgattc actcctgtgc aggctttcga cagagtatgt aaaaacccgt tgcttaaaat 6780 caatggcata agatttattc ccatgacaag gagcatctca aggagatcta atcaattgca 6840 aaaaaaagtt atgtaaataa acgtgatgaa atccaaactt cttagcaaac tcaataactg 6900 aaaagcgatt agtgttcatc tcgtaagact tgctagtatt tttcctagct caaaatgtac 6960 catatagtag gtaaattctt tgtgtttttt ttaatttttg gcgttttctc attttttaaa 7020 ccaaatcaga atttaaacaa aatatgttct gacaacacta ttcaagccat caatggcggg 7080 taaaatgtaa agacaacgaa aactgagtac gaagttttgt tgtaggtaga ggaaggggaa 7140 acacggtcaa aatgattaaa gggatagggg gtacttgtaa gttattaaac ttataagagt 7200 gaagagtaaa agcaatctag acagaagata tagttcctaa aaagactgat agttcgtgaa 7260 tgctaatatg caaaaccacc aagatatcaa cctttacaaa tgctaatgtt tccactgaac 7320 ttaagaacac aatttaggct tttaaataat tctcgcgata aacagtacgc aaagaaaacg 7380 cacattcaac aaaatttttc gtatgtgcaa tagaagggaa aaatagtttt ataaatagta 7440 aaacgatata attgagccga aaactccaca cataaccaga aaaccaatag taaatagtaa 7500 aaattgcaaa taataaaatg aaaaaacttt cctaagtcat tttatcatta aatataacgg 7560 aagaaaggaa aaagaaaaga agaagtaaag tggacaacaa agataaacga aagcgggcaa 7620 gcgaataagg ctcaagtatt ggcgaaatca atatgcaaaa ataatgtaaa aagtatgaat 7680 tagaaaaatt aagatagaaa gatagctact aacgaaccat cagcgaacgt caccaaacct 7740 tcagcatcaa ctcttgaatg cttgtactgt ggataatacc ggctcactgt gtaagctaac 7800 tggcgatact acttcagaag aagaggaatt tgaaggaggt gaattgttat ccgtaggagt 7860 aaaagagaag gcatcaggat agtactggaa tggacccgaa gattgcttct ttttgtgaaa 7920 cttattgcga gaatatcgcc gagaattaga caaatttttt tcgtgacgat ccccgccatg 7980 cctctcatca aaatggtgtg aagatttggg gtagggagaa ttataccatg tataaaagtc 8040 catgtatgag ggtggaagat agctattatt attaatatag catgcatagg tgtaagggtc 8100 aacaaaggta taagggacat tgggagggat tgcagggacg tcgtttgagt atatagaaga 8160 gtagtcaatg gatgaattaa tattctgatt ataataggga gaagcggttg cattataagg 8220 atcaaaggcc caagcaaaat gtgatggctc aggaggggat tctgtacagc tggtgtccga 8280 agagtcacga ccatgggaga aaccaggaac tatttccaat tgtagttcat ttacataatc 8340 gtccataaag cttgtgtcag ttagagaggg aaaagtaaat tgcgaacaag catcgtcgac 8400 attgcaatta tacgctaaaa gacggaaaac acgtcgaaat tccaattgta ttcctttcat 8460 ggtaatctca tctgcagtat tagctagatt tcgagatgta tggaaaggct cttcaacaca 8520 cagaaaattg ttaagctgaa attgccatcc ttttgctcgt ttcgaaagaa aggtaccgtg 8580 tctaatggat aaaacaaaat gctcgtaatc aaataaataa ccaaaaaatc gaaaaaactc 8640 tacgaacagg ataccaagag actcctcgtt tttgtcacca aaaccatgaa caagatctgg 8700 atcgtcgaaa aacgacacat ccagcccgtc agtcatagta gacgaatctt gtaaatgagg 8760 aagcatttgc aagctgggaa gaatcggtgg atcgcgcttt tgtaaaaagt ttataaccat 8820 acagcttatg gtgtaagaag tgagtgtacc gccctcggca gcgtcattca agcatcgtct 8880 ttttgcccaa tatttaatca taacaatcaa gggccgaact cggggatcac aaagaacgta 8940 agagcgcatc aaacgcgtgt ttaaggtaga tatagtttta ttgatattgc aatcgcatga 9000 tagttgtaat tctgagtccc aaacctttac aattggcact ttagctgttg aaatgcaaac 9060 gaccttttta agtccgttcc tagcaaaggc agctgacacc tcgcaggtcg ttggagcaca 9120 ttgaggcgga tcagtaatga tacacaaatc aatgtctgat gcattgctgg caagaagaga 9180 ttgggttgac ccaaaaaggg aggttttgat atttttatag gggaattctt ttttcaatat 9240 ttgttcgagt ttctgcacaa atgcatatcg acgttctaaa cccgagtcgt tcagtataat 9300 agagtcatac aactcgtaca gttgagaaga aattagatca gtatcaatat caactaaatt 9360 ctttaatgat agaggatgta ctggcggaag tggatccgca ccgaggctat aaggaatacg 9420 ccttctatat tgaaagctgc gagtttcaaa tttgcaaccg ccaacgcaat tagcgttgtc 9480 catagtatta agagggtaag aagcttctaa ggtttaataa gttgcaaatt ctctatggat 9540 tccgacgtta tcctaccttg tcagctagta aaggcgtgag ttctttgtaa tatgatcagc 9600 tttgatctga aacgatccag caagaacagt tcaaatgtac gagccctatc gacaagaaaa 9660 gacaatttag aagtacttct aagtttcaag atcgtattga tgaattaata tgaagttggt 9720 aatgtttgta gctattctta ggaagaggtg tgggataaaa gaaccgccta acagcaatac 9780 gtacgtacat aggtatcagc tttcctacac aaggaacaag tacggcatca acataggatc 9840 ggtaaataag taacaaatga atatacaacg ccgttataaa gtaaccttaa tatattcacg 9900 taagacacct ttaaagcaac gttcagctaa tgatattttt acaatcttca actgaaaaca 9960 ataaacaaag taatcatcaa agaaaaaacg caaacaatga cgttggcatg acaacgagca 10020 taattgacac ctttcttgac gttttgacgt taaatagcgt gattccgtaa tctgcgttat 10080 tctataaaca aactagcaat acataaacat acatgatcaa tgttgctccc acaaagcatg 10140 gacttgactt tccaattgag tggaaacgtt cgtgtaatac tttactacta acgaatgtac 10200 agcagacaat attaaataaa aaacgccgcc aagtaagcta tccatctaac tccaaatacc 10260 atacaattga ctcctttaat aagaaacata aatcaaacaa tctaacggaa tttgaaatcg 10320 tttcatttat tcactaaaat ctacgctaaa acatgacaca acttcatcta gaaattacat 10380 ctatgtcatc aaacgacacc acagttgtaa tataatagat gaaattaaac acgtcagaaa 10440 acaccagctg ccctacataa tacgaccaaa aggaaacata tcatgtaaga gatcatcgca 10500 tagaaagaca gcaaaacaat taggtaaaaa acctaatcga aaagcatgcc ttcaaagaat 10560 taaaagtcct cactctgagg gcaacggtgc ctcctatcat catccgtgtt gagttctgtg 10620 gctaggttag gaaacccaag ccggacgtat actatagaaa tgatcctatg gagtatcgtc 10680 gatagtgttt tgttgaggat aatgacccgt atatatagta aatataacgg aaaagcagtc 10740 acattcattt ccaatcaacg aataatgttg aactttcaag tataatgcag tgtcaattac 10800 actatattaa aaagactttg caaggcggtg aagctgctct taaattacaa taagcatgaa 10860 aatcatattt cggtaaatta gtaaaagaag tcatgaaaat agagcttaag gccgagaaaa 10920 caaaaaaaaa atttacaaat tttttaacta gttagaaaag gtttaataaa actggtaggc 10980 tcctctattc tataacttgt aatcgccgac agccatggct ttaaaaagtt gctacttgtt 11040 gttacttgtc attaaactgg tgaacactaa ctcctttaga agttcgtaca gcaatttgca 11100 cttcaaccaa ctacttggca gacttaaaaa acatgtctga tacaacttca ttgaatgtgt 11160 aagaatgact aagatatata aataactaat tcagtagtcc agaattggag tctcccccta 11220 ttgagcgggt ggaattagaa tctttacttg taatgaatat catcaagcac tgccgtgatt 11280 cttttcctaa tatgggaaca attggtaagt gtagtcattg gagaataagt tttccctatt 11340 tttcgaaatg ataaaacttg caatttttct gcatcaaaga tgcagctatg catttgtcag 11400 ctcagtaatg ctctacttag tgaaatttct tatcaaccac agtttctctc ttgaaataat 11460 atttttaact aactttcgtt caggtcagct tgttggtatt gacattgatg gtgttttaca 11520 agtcagtagc agcttcgagt ctccgtctgt tcttgaaaat gaagagtctg ctgttaacaa 11580 gtctgtttcc ggtaaagcac gccaagctca tactgaggcg atgcttaatc gtcttcagta 11640 cattggtgct gttactggtc acgttggttg gtatttggga gcctatgtta gttcattctt 11700 aagtagcccc ttttttgtag aaacgcaata tgcttatcaa aaggcaaacc ccaacagtat 11760 cgcttttctt tatgatttgt ctcaatcttc taatggaact ttgtacatgc gtgcttatca 11820 gttaactcca gagtttatgg ctgcccatga ggaaaaaact tggaccgcct cctccctcaa 11880 tagccacaac ttgactcctt ccaatgttat ccgtgaactt cctattgtta ttcacaactc 11940 tcatttggct acctgtttgc tccactctct tagtgagcct cctactccag cttctaccct 12000 aaccgccgaa gctgctcttg aagattgtga aagcaactta cccttgactg aaacgttcag 12060 taactttgag gttagtttgg gtaccagata tagaaagaat attgagttat tattggagtc 12120 tactgatgag tttcattatg agcaaggaaa tcttggattt catcaacgtc aactcgcaag 12180 agagcaagct aaaattcaac agtggattgc taagcgtaag gccgaaaatg caaatcgtgc 12240 tgccgaaaat ttacaacctt tacctttaga cgattggaag cgaatcttca agctccctgc 12300 ggagcctcga cttcttgact ctctattgat tagctctcaa attatgaagt ctactcaaat 12360 agatgaacaa agttctgctt tcttgtctaa gcttgccggt gtacgaaacg cttatgcttc 12420 ttaagctact gattggtaat aatcgcttaa atttagcgct aattatttgt gaatctggtt 12480 gaaaattttt aaggactttg atctctgtga agcggttgca tgtatttgtt tataaaaaat 12540 ggagcattct tcttcactct cactagttat acctcgtagc attaaaataa aaggatctac 12600 ttaattataa aagttgtttt ggttttcttg atacagcata ttggtttgtt gaaatacaat 12660 gtgcaaaaat ataccatgat tgtaattata agaaacagtt taatcttcaa tagtgcattc 12720 agttgctggt aatctacttg tttatcgtat tcgagtttta ggttacattg ctaatttaat 12780 atattttcgg gcccttatac aacatcgaaa cacttttcta ttaataaaat atattgttaa 12840 attttgtttt ctctctgtta gattatttaa aaaaaaaatc gtaaatattg ccgagacctt 12900 tttgtttgtt ttgacttgct tcacgttaca atgttgactt ggccaaaacc aacaaattcc 12960 aaattcattc aattcgcaac ttgcaatgga agttccttct gcagttaccc taaataatta 13020 tgtgggtatg aaaacaaaag aatgttgata aagagtcaaa actaatgttt atagggttcg 13080 attctatcac ttcgcaaatt aaccgcaagt taattcgtcg tggttttcaa tttaatgtaa 13140 tggtggttgg tacgtattat ttttattaca gattttcaat tataatgatg ttaacagttt 13200 caaataggac cgtcaggtag cggaaaaagc actttgatta atactttatt ctctgcgcac 13260 ttgatggaca gtaagggtcg tctggattac caagctcctt atcgccagac aactgaaatc 13320 catgttacaa gccaaggtat gttgattttt ttatagttag gttttcatct ttgattgaac 13380 tcattgagct ggcttcaatg agtcagcaat ccttatattt attatggtta cattgctaac 13440 cacatagtcg ttcgcgagaa ccgtgttcaa ttacaattaa atttaatcga cactcctgga 13500 tatggagatc aaattaataa cgataaatgg taagtttgat cagtggaaat ggaaatttct 13560 attcctgcac agcaatttct aactataata gctgggagcc tataattaag tacattaggg 13620 accaacactc ttcctatctt cgtcgtgaat taaattcaca tcgcgagaaa cgtctacaag 13680 acacaagagt acattgttgt ttattcttta ttcgcccaac tggacattct ttgcgcccta 13740 ttgatattgc tgtcctcaaa cgcttaacag aagtcgtaaa tgttgtgcct gttatcgcta 13800 agtctgattc attgactctt gaagaaagag cagcatttaa gcagcaaatc cgtgaagaat 13860 ttgttaaaca cgacatcaat ttgtatcctt atgattctga tgacgccgat gaggaggaaa 13920 ttaatctaaa tgctgccgtc cgaaatctta ttccttttgc cgtggtcggt tccgaaaaag 13980 ccattatcgt agatggaagg cctattcgtg gtcgtcaaaa cagatggggg gttgtcaatg 14040 tggatgatga aaaccactgc gagtttgttt ttcttcgtaa ctttttgatg cgaactcatc 14100 ttcaagattt aattgaaacg acctcatact atcattacga gaaattccgc tttaagcaat 14160 tgagcagctt aaaagaacag tcttccctcg caactagaat gggaagtccc gcacctgtgt 14220 acccttctga accacatctc catacagcca ccgctcaata gtcttcttcc taaggtaata 14280 tatagtatgt ttagaacaaa gactaaacca tttgtatgac tgtcgtaccg taattcgtaa 14340 atttcggctc tttttacact atgcgaatct tacaaatgaa gtgtttatct tattaacgag 14400 agattatatg tttgatgcgt gattttgtct agctattata cagttctata tcaatattta 14460 ttgaaaagca tcaaaatgat tttaaaatta aagtactggt cgatttaaga cattgcaatc 14520 cataaaatgt tctagcatca atcttccgaa atgagattcg atttgtgccc gaagtttaaa 14580 ttctttagag tttgatgcaa aaacattttg tagagataat acgcataaat aggaagtgcg 14640 taatactgca atatctgtgc attcttcttg cattaattgc tgtaagccag aaagaacgtc 14700 attattgttt ttggtaacgg catgtcctac acaatctata actttagtaa gaggacttct 14760 tgatgctgaa tacaagtgca catgatattc atctcgccaa gcaaccattc gttctcgatg 14820 caaatcatca gacaaggttg gttgagagag aatgtccaat ccaatagtaa acaaagaatc 14880 cgaaacaggt gcatgacttc gagaaacaga aacttccgat aaaggctttc cattaaaccc 14940 ccagatacac ccacgaggaa gaattgcaaa aactagttca cgaacgacca tagcaatcaa 15000 taagctgaca taatttgatt tggtagacga agaccaactt aactttctaa taaaattatt 15060 acaaaaattg agatcatagg ctgggagatt gagctgagtg agagtcaaaa atgcagaaac 15120 caacaggtat tcaaaagaat tgggaccagg cattggacag cgaagagctc tggtcaaatg 15180 actgtaagca ccaaaaacgt cgagcttctt aatagacgca aaagccatta aagaattagc 15240 aatacaaggc atcgattgag caaactgggg aacagtgact gaccaaaaat gcaaggctat 15300 gttattatca aattcaaatg cacaaataga aggtacgaca tcgtgaaaat aaaacggaaa 15360 cagttcggaa ttaaagtttg aagggaaatt ggaaactgat gaaagaaaag ggtaagaggc 15420 ctgacccacc gattgtacag agggttttgt agacgaagta gcgctagaag aattatttgt 15480 aggaacgtta tgattggatt gaaggtattg atgctgttga taagcacttg gaaatccttg 15540 taaattcata ggtttttgat gatcctgttt gattggggta acggtggata aattggagga 15600 ggaggtcatc tgattaagat catttgtatt aaaattggat tgtgaagagc cggaaaaagt 15660 gtctccggtt tgagcgctac ttgaagcaat tgaagtaggt atcaatggct gttgagcaga 15720 atgaacgctt agctcaggag gcgatacact ccccatggct tgcatttgag cagctgaatt 15780 tggataacct tcacattccc tatttgtctt tgtgcagttc aaacaaaaag gtttggtttc 15840 gtcgcacttg atcctgcgac ggcgacatgt taaacatcca gttttcgttc ttctttttgt 15900 gggcttgggc gtaggctcga cgtttgggtt gggaatatat agcggatttg aattaatact 15960 acccgttcta ttccgtttca tatgaatttc gggataagaa acatacgggt tcataactgc 16020 aagggaaaca atagatagaa aaaaaaagaa taacaagata ataggaacta aacaaatcaa 16080 aagtaaagaa agcccgattt gaaaacgcta cgctgcttga gaaaagcgcg caaagaaaaa 16140 acgcaagcac agaacatgaa attggaagcc gatttataca aaatttaagc tccaatttaa 16200 caaggaaact aagcaccttt ttcgtaaagg ccaagaaact ctttgtagtc ttttttttaa 16260 aaaaggtagc gttactaact ctataattat atatatatga atacaataaa ttatttcaga 16320 ataaccggac ggccaaactg ttcgtaataa caaaagaaaa agccctaaaa aaacaaaaga 16380 aggtgaaaat caatggtcgt ctagcaattt gctagcaact cttgcacaat caataggttt 16440 ataggaagtg acttgaaaac aaaactagca aaagcgacaa gctcacccaa tttacaaatg 16500 caaatttggg tgaataaagg acttagaaaa aatgttggaa caactttcaa gtaggaacct 16560 cgacattagc gagtgataag gcggcaaatt tgataagccc aaaggcaaca acaatactaa 16620 gagcttttta tttagacgtt agtaaagtag cttgcttgat acgcattagt acaaaaatcc 16680 aaagaattga gaaaatcacg agccaagcaa aaacagtata agaacgatta acttgtttaa 16740 cctctaatgt tcttttaaaa ataaaaaaaa aacacagatg tttcgttaat tttttgatac 16800 ttagattatg ccctcatgtg tttcataaat agcattcctt gcttttcgtt tttttctgtt 16860 ttttttcttt ttctttcaga caatttataa aaaaaattct ttgcatgtac ctaaatatag 16920 tttgcattct catttaggtt gatcaagttg gttaataacc acgtggcttc gaatatctgt 16980 catgttcagg agccacatgt ctctccattg ttacagcgat ttggttgatc tttacatggc 17040 ttacgcatac gaagatgctt cctgcatttt ttttttattt caaatcgttc attcactctg 17100 cactagcgaa aatcttcatt catatgcaaa cttgtcactc ttttatatta acaaaatata 17160 aacttaagct tgaatacaac tgttagcttt gaacgctaca cctaccctag taccctagta 17220 gcttgataac catagcgaag atccgtggcc tattgtcgat ctctgggaaa ctgtcactgg 17280 atcaaaagca tcatgtttct tcgctcggta agaaaactat actccagatt tatgagaaag 17340 gcacaaaaag catcaaaacc tatgccaatg caagtctcac aaaaccaaat tatccacccc 17400 taaaggtgga attgttcgtt gttcgtgatg cgattattgc tttatcagga tgattgtact 17460 taatctcaat cagatcaccc caaggttagt cggctttgtc aaaggtctta ccttttattg 17520 aaatccatat cctcctgtaa caatagggga ttcactattc atacctagtt cacccatttt 17580 tctcatttca cttcttaaag caaataacgt ataataacag tatttgttta ctgatgagat 17640 taacattacc cgatgaagaa aaccaactat ggtacagcaa taggtagtta agaaaataca 17700 tgagatcgta aataccaaat gtttgccaat tatgagcgtg aattagcatt agtttttttt 17760 tttcttaatt catctgtgtt tcaataatac gaattagatt gataagtttt tttttttttt 17820 tttttttttt ataactacct agtactcttc catgatgcga acattataac aacaatgaga 17880 ccaaaatatc tttagcgatt ggaacaacaa ggtcacattt cggaaaaatg atttgccagg 17940 ctgaagattt atattaacca acttgttctc attaaaagcc aaactattga atttacaaat 18000 ttgttatacg agcatcaatc ctattataat aaaatcgact caagttgaat tgtagcacat 18060 attatttatt cacgagtcat taaaatatta gtttaaacgt gtcaattatc ttcccattag 18120 cgccaaatcc aaataaataa atagtgagta actgatgcaa catagtgatt cgacgagcta 18180 aacgttgaaa tctaaaagaa actggtgttg ttcaacggat tgttatgctg ctggacgggg 18240 ttttggtaat tggaatgggc cttttaacgt ggtccccatc ataaactcgc caaaatttca 18300 gattctcatc actggctgca gttgaaagaa ttcttccatc aggcgataaa gctgaataca 18360 aaactcgggt atcatgtgca ggaatatcaa cttgtttggt taatccgctg ctactataag 18420 accatataga caaattgtta tctggaaagc catgagtaga catgatttct ttagaatgag 18480 ggctccaaat cagtgaagtg acctgactac ccgcatccac ggtgttaact cttgcaccag 18540 tggcagcatt ccaaaagtga atctgtttat ccattgtgcc accgcctgtc gccaatagat 18600 tactttgcca agggcaccaa gcaactgcct ttacagcagc gttatggttg gttttggtaa 18660 atttgggaat cgaagatctg gcatcccaaa tttgaacaac gttgtcatta ccgccagagg 18720 ccaactgaag accgtctgaa cgccacgcca aaccacagac ttcactagag tgtccctgaa 18780 gagtcccaat ctgatgatta gcgatacgca catcatgatg atgaatagcg ccagaacggc 18840 taccactcga cagaacgtga cgattccagg agagacaacc aactctagct tgatggcctg 18900 ccattgttcg aagttttgtc tgtgattcaa catcatatat atcaacgagc ccgtttccaa 18960 gaccgacgga taaaaatgaa ccatcgtgag accattttac actagcaaca taggttgatt 19020 catcggtttc tgccaaagcg ctaaccgaac cactatcagc attccaaaca tacacattgc 19080 gctccaaagc aacagcaacg acgtttaagt ttgaccaatc cagcaaattc aagtagtaat 19140 catcaatgat accaggagca tctaaaactc gttcaggagt agtgttaaag cgtcgtttag 19200 ccggtgtaac cacaggtctt tgaggccgat tgtgttgagt gcgcaagtct acaggctttt 19260 tggcctcagg agcatccaat ttaaaggcga gaacacgcgt gtttaaatca aaaccgcatg 19320 cttcagcaac tgattcacta taatcaaaag gaacgtcact gctgatagaa tttacaaaag 19380 cattagcagt gtttggacga gaaggaataa agcggtcact tcgactggca ggacgacttt 19440 tgtttcgtgg tgatccgcat agtggaatag accaatctgt atttactaca tcgatttttg 19500 gtgagtttct gataaaagaa gatttagggg agcaacgctt ggaagaacga ccgttacggc 19560 ctaaaagtgc ctgctgatgc aggggagtta tagggctgtt agggaagact aagttccttt 19620 tctttgtggg tgttgaaaat gtaggcgata tggttgaaga attacctgct atctccattt 19680 tgattaactc gctcaaaata tatatgtaaa agaaaaataa tgcaagaagc gaatatcaaa 19740 ggacagaaac gtatccaaaa ctttgaataa aacttctaat gaattagaaa taaagtggat 19800 ttcaatttct ttttgttgta gaaaagatga aagagaaaaa gaaaagcgaa gaaagaaaag 19860 actttttaaa aattcaatag gtaagctata taataatgta acgttagtag caaaaagaat 19920 tcaacttttt tgaaagcctt tattaatttt ttaagctttg ttgttgctgt tttttttttt 19980 agagaaaaga aagtgcgcta acaaataaag gactattagg tttcgtaaac aaatcgtaga 20040 aggagaaacg aacgtcttca agaattaatc gattttaagc aaatgaatga ctttatgatg 20100 accggcacca cagcgcatta attaatattt ttgaataatt ggataaaaga atgagtcgag 20160 tgctaatata gcaagcaatg caatgcaatg aaataatatg tgaaggagaa cctgctcaaa 20220 gaaataatct attaactgta taaggaagag ataccagtct tttccttaag acaaacaata 20280 taggaccagc ctaatatatc aaagaaaaag gatccgaaga tactaaaact ttgtaacgtt 20340 gaaattcaaa gtgtttagat gatttgttta caataaattc aggaccacag cgtttagtat 20400 ataaatgctc tgaataccct aacccttggt tactatggct accacgtgta aataaacaag 20460 agtgaacaat atttacagct tatggtaatg ctgcgcgtac agttgaggta aatataacaa 20520 caaactcttg ataaacaatg tattttctac ttttatacta aatatattta aattctactg 20580 catgtttgtt ttcatttctc atcaaccccc cagtttaaat ctgctaaaat ttgtaacgca 20640 tttcaacaat ctatcccgta ttccaaccac ccatctttag caaagcgagt gttttgtgtt 20700 gttgctttgc tacacgctac cttactaaac aactggacac tttccaaaca atatgttgcc 20760 tgtacctatt tttgtaaaat ttctgtattt agcaatctat tgaaaagtga ttttttacta 20820 tttggttatt taataggtat cctgaaccct cacgaatcac caagcatttt tcaattcaaa 20880 ttacataaat atatttactc ccatgttcca ctgtcaagaa attaaatttt cgcgagcgcg 20940 tttttaataa gtagctcttg gcgaaatgct tgtatttgga aaatctactg atacttacta 21000 ctcctgaata ttatttcaag tactatctag ataccaattg ttttatccca cgcgtttcta 21060 cttttcgaaa gccaccggac gccaaaatat ttaactacct agctacttaa cgtcattttg 21120 aagagtatca tacaatcaaa taacgccaaa gtaatgtttc aagttgtgtt gtttacattt 21180 gcttatgtat aaacagtttt tcttaaaaag ggctggctgt taagacatcc agatttccgc 21240 cgaccaccca catttgtcct ctttatggta aatatggctg gacatgctaa gaaaaaggac 21300 atgatggctg tccaagtttc caaatttgga ataatataaa gtatcaaggt tcgcttttct 21360 aattactata acctaagtaa gacacaacct ccttattgat tgtaaacaat cgggaaatct 21420 tgaaacccaa gtgataccta atctggaaaa cttaagaatt tactaatcca tatccactta 21480 actatcataa taacattgga tattggagtc taataaatcc ttaagcagct tcttcttaat 21540 tattgtatta cctttttgat ttcctcattc tttgtttcat ttttttttgt tactttagca 21600 attttagttt aaatctttta ttttctctgt ctttcctttt agtcattttt ggtttgctat 21660 cttttcactt actttattgt taggaactat gagttcctat ttacgttctt ttatatttgg 21720 tcttttgacc ataagtttgg cacaatgctc gccaatcctt aaggatacca aggataccaa 21780 attttccaca ggctctaata ttagcttaaa aaaacgtgat accaatgttt tcgactctgt 21840 tgttgatact atcaacccag ccagttattt cggcaccgtt tcgcacccag ttactcctgc 21900 cggcgtcagt actgacagct tgagctcccc tattgaaact aacaaatttt ttgataataa 21960 tttacttggt tctcgtacta atttcatgta tgctgatccc ttcagatatt ggtggcagtc 22020 ttcagacacg atgggtggca tttgtattgc tcataccgat gacaatcaac gtgtaatgga 22080 tacggacgat acaatccctt cctattatta tgaacccatc ggtatttgtt cgctcggatt 22140 tggtgcttct ggtattacct ctaatactga cccaattgtc gacgagattg atcagatgtc 22200 tgctcgcttt actttctctt gggactcttc gtctatgcaa cttactttga ctgagggtat 22260 ggccgttact actgctgtct acactaatgc tattcctcaa attttttcat ccactcttta 22320 tatcaatgac tttgtcgaag tgccgggtac ttctgctgtt caaaagtatc gtgtcacgat 22380 gtctgataac cacgtttggc ttatttacat ttatggggat agccttacgt tgactgaatc 22440 cacatctcaa atgcttgttg gaagcaacac tttcaatggt tacattcaaa tcgcgaaaat 22500 tcctcttgga gatggcaccg ctgaagctct ttatgacact tatgcgggtg tctatattac 22560 cggtattagt atttccggat atgttgagga tgctgttggt tattactcgt ttgattttac 22620 gactgctggg gatacttcag tagagcctct atttttctta ttgcctcatc aagtggatac 22680 agctgtcagt ggtaccaaag ttacatccat tgttttggct tctctagtaa gtggtgatat 22740 gaatgccgca gctggaaact ctataacatt cgccgaagct attcctcagg acattggttt 22800 tcttccatgg tcgccgacag gtggtcagat tggttattcg gaagaagcat tagagatcat 22860 cgctgaggtt gctggtactg aattgggcga agacttctct gccaactcta atttgaattc 22920 aatgtactat tctggcaaag ttttggctaa gtatgcaatg ctgtgtgtta caattaatga 22980 tattcttggt gatgagacca gcagcgaaca atgtattcaa aaactagagg ctgcttttgc 23040 ccgttttgtt gacaatcagc aaatttaccc tctgacttat gataacactt ggaaaggagt 23100 tgtcagtgta gctggtctat ctggtgattc cttggctgat tttggtaaca gctactataa 23160 tgatcaccat ttccattatg gttattttgt tttcactgct gctgtaattg gtcatattga 23220 tcctgactgg attaacactg ggaacaataa ggaatgggtt aactttctag ttcgtgatgt 23280 tgccaatcca tcatcaaatg atccttactt tccaaagcac cgaatgattg atatttatca 23340 tggtcatggt tgggcatctg gtttgtttga gtctaatgat ggcaaggatg aagaatcaac 23400 gtccgaagat tataacttct ttttcggtat gaaactttgg ggtcaagtaa ttggcgattc 23460 tgatatggag gatcgcgcaa acattatttt gggcattgaa agaaatgctt tgaataagta 23520 catgctgtat gctgatggaa acgtccagcc cacttctatg caacctaatt atgttgccgg 23580 tattacattc atgaacaaaa ttactcacac tacctatttt ggtactaata ttgagtacat 23640 ccaaggaatt catatgttgc ctatcactcc aatttcagct tttatccgtg gtcctagctt 23700 tgtactagct gaatggaatg ccttacttgc tagtgtcatt gactatgtag atagcggttg 23760 gagaagtctt ttatatgcta atctagctat tgctgaacct gaagaaagtt atgaatattt 23820 ctccagttct gattttaata ccgattactt agatgacggg gcctctcgtg cctggtattt 23880 ggcttatgcc gctggcttat gggctaatga tgccgtttat tatcctgtta gctcttcttc 23940 taccaccacg acctctacga gtaccggaag tgttacgaca acctctacta ctgcaactgc 24000 cagttgtaca ctacctatat cctatacttc gactcctact actacaagca tctctggtac 24060 ttgtaatggt gctacgtttg atgcaagttt gtatgtatgc gacggaactg tactctgccc 24120 tattgttaat ggtgtatcat atcaaaactg caacggagct tgctataacc cttcgcaata 24180 tggctgcgac aatggagctt tgggccctgt tcaatcttca tcgaccactt cctccattac 24240 gcctactccc acaactactt cctcaataac acccacacct actacaactt caacaactac 24300 taccgcacag tcaactggca tgcaactatg tggctctaac tactacgacg catcctctta 24360 ttattgtgac aatgatcagt tatgtcctat aatagacgga gtggattact tgagttgtaa 24420 tggtgcatgc tataatcctt cccaatatgt ttgttctgat ggttctttgt ctccaaacac 24480 tgttacaaca acaaaagcta ctacaacttt cacacctaca cctaccacaa ctactacacc 24540 tacacctact actacatctg ctacatccac taatgtgata gcccaatgtg gatcagcttg 24600 gtatgattca caaagttata tttgttatgg caatatactg tgtcccatta taaatgggtc 24660 tccattgtta gcttgtggta atgcgtgcta tgactcctct atatacggtt gctccaatgg 24720 tgcacttgtt gctgcttaag catgaccaaa gtccggaatt gtattgcgag gtgctttttt 24780 ggatttcttc agatgtacta tacttattgc ttgtatgttt tcaaactatt taaaaaacta 24840 cattttgttc ataatacacg tctggaacgt gaactactct caacttgaaa ccctttttgg 24900 atatcgtcta ggccggctta gagatcaatt tattaaaatt attcttgctg agtttttctt 24960 ttttgcatct ttttgaatta gttggttatt atttaaccac ttattttatt aattgttcac 25020 actggatgtg aacctttaga cttatagaat aaaatttatt ttaaaataca acttgtgcag 25080 atgttttcag tttacacaaa cttgcctgtc gttattgttt agttgaaatt agttcgtaaa 25140 aattcattga tacgtaaaag taataacaaa atcaacaaag atgaaacgat ggtattatga 25200 ttaataaaaa aaaaggcttc acccattaga attttaacaa gatgtgttga tattgctact 25260 atgtgtgtat ctattaatca acattctata tatctttttt taaacaatac gaaaagcact 25320 ttctatcatc tttatgcacg aactcaacga tgcaaaacaa agttttctga ctaaaagatc 25380 aaaaattgtt gctgcttttg cttcttcatt atcaataccg aaacaaagtt acaacaattc 25440 cttctaatta actgaatttt atgtaaactc gaacgcagag tcttaaggac aaaaatacat 25500 cactacattt ttttacacat ataacataat agtaacaaac agcttccaca aagctacagt 25560 acttatcatc atcaattaaa ttaagttttt taatacagaa cctatagaag cataatatac 25620 ggaacttttc ataaaaaaaa agaaatttga gatcactcaa ctaaatgata acaatactaa 25680 ccaacaccta aacccacagc catttgaaca aaaagacgta aaaactcaat aaatttagac 25740 ggcaatacca atgacaccac aagcgttacg tgcaccagcg ttaccagtct tcaaagactc 25800 ttcactagta cccttaccaa gatcatcctc accggcatga atgacaatgg tacggccaat 25860 gatgctgttg gcaccaaaca atgagataac agaatcagag aaagtagtct tgatgttgcc 25920 ctgagcatcg ctttccaagt taccaagatc accaacgtga cgaacagcgg cggtacggtc 25980 accgtgagtc ttaccctctg ggttaaagtg aggaccagca gaggtacaac cgttggtatt 26040 atcaccgaat tggtgaatat ggaaaccacg cttggcatta gcgtcattgc caacgagatc 26100 cacaatcaca gaaacttgag agttttgatc gacttgttca aaagtaacga caccactgac 26160 cttagagtca ccacgaagaa ctgctacagc tctaaccatt ttgtatgacg ataatttact 26220 ttaaaaaaat acaacaagag aaggggtgtt ttgagtaatt aagtgttttg aaggaaaatc 26280 aataagattt taaccacact tcaaagttgg agatttcgaa aattttgttt ggaattggaa 26340 gaggataggg cggcgtgtca tcgcttatat agtaaatagc tccacgcgga atatacatga 26400 aattttaacg atatcaactc aaatcaattt ttcgatatga ccaatgtttt tttatattct 26460 aaaaacgaag aaattgtctt tatacttatc gatttaacaa atttgcttta caaagcattg 26520 tctagtccgt gccttcgagc ctccaaaata ggccaataag ctacgccgag catcacctca 26580 gcttggcgtt ggcttactcc accagtattc gtaatcatat tacgtgctcc ttcgcggaat 26640 tgaaattccg ctaaagatga taacgcgcca ctcgaagaat aaataacgat atctaaagtt 26700 gcggtaatag caatcgtcgt tctcgttttc gtagacgtta aaacatttag cgtaaggtaa 26760 gaatgaccac gttgaagtaa ggtcgctaat gggggtaaag atcttcaaag aaagggaaac 26820 ttgagtagac aaacattgca tagagattca aatgcataga ctagctaaaa tatcaaaccc 26880 ccatttggtt cagtaaatcc cactagagtt cgcagaataa aagtcctaca tgtatataga 26940 ttagcgtttt gagtctaggt gtgaagagcc taaggccggt cggtagactt gcaaagcccg 27000 ttcgttcacg gaagttgtta ggagcaatcg cttgtaacag tcaaattgtt atgaagcttc 27060 aatcgacgtg aggaggataa taaaattcgc tctagaaaga aatattcgtg aactcataat 27120 tttcccataa tgaacaaacc tctcagtatg catttttgag aaagaatcgc aagtacaact 27180 gctgataata tcattgagct tttaaaaaat aaaataacat aaccatagta atgctttgta 27240 ctaggaagcg agtgacacta tggttatttt ggagttaaaa aaaatcctga tgatctgttt 27300 tgcaaatacg ttaatcgctt ctatccatcg atctacctac atattatttt ggtagaaaac 27360 agaaaaagtt ctctgagggg gacgctgttt atataagaaa tttgccaaga tgtataaagt 27420 attatgccga aaacagtaat taccttgagc tacttatttt atatgactta tttttgctat 27480 tcgtgaagta gcaatatgag actattttgc tagtgcgcga aagaaatggc tcattacaaa 27540 aaatagcgtt tcgcataata ctaaaggcgg tatattccta aatacaattc tcttaatcat 27600 tctaccgtaa ttgggtacat tacgatatgt cagcaatact acactacgct atgatacact 27660 acgttgcgta tcactatatg tcatatgttg gaatactagc taagatccgt ttattgataa 27720 tcacgggtaa ctatccgtct atatacatag atacccgttg ataacaacta tttagaaata 27780 ttataaatag cgttacaact gaacctcgtt cctcagttca gttatgagct atattagtga 27840 taggtaacat tatagcccag ttaatacaat acctatactc agttgctact tatacaacct 27900 gtgtattgta atataataga ccacaaggaa aactcaccgc agttcttcgt atccttaaat 27960 cagataccaa actgcgtagc ttacacgata cacttaataa cgcatatcct caaaatactt 28020 taactcttgg caatgggatt gatgagtaga atgtgtgcga tttatgctca tgatttgtac 28080 aacttgactt tggagaggta gtcaagaatt ttctgttagt gtatggaaaa accttgatgt 28140 gattcactgc tgtacaatca agcatagcta cagagcctta aatatgttgt tattgaaagt 28200 aaacaaatga aatactatac acccagatta ataatttatc gatttttttt gaagcaaagt 28260 atttctttct gattctataa attgtcgact tgggggacaa ttgtgaaact gtaaggcaag 28320 atgaactttg caaatatgga attaaattca aagtaattgc gttcaaatta aaaaaaaagt 28380 actatattaa tgaacagttt gatcagccat tgtaaacaat tcaattacaa ccgttagcga 28440 tactctatat tgaaggatgt tttcccgaaa agatgaacaa acaattttgt ttgttgagct 28500 gtgcatttca actagaagca tctttaattt gaattaaaaa caactagatc aaattgattc 28560 agtaataact ggacaccatg ctaataaatg tttttgcttt tacgatatga ctataattta 28620 ttcatgagaa atacgaagtg tgtaataatc caaattctct atggaatata caaagcacac 28680 tttaaaatta gtatctttgt atttcttaac cgaagatacc cagttgctca ttttttagtc 28740 ttttgtttac aagcataatt cttgcactac gtgaaaagtg aaaagtaagg ctactatata 28800 tagtaacgga aaaacaaaaa ctgaaaatat aacactaact gttcttgagg ttgcaaaata 28860 tttttagtta actgcagaag tactctcact ttccatgatt tcgtatcttt cagaaatctt 28920 agttatgctt aatgtaaagt aacaatgctt gattttgtta cttgaagggt gttaaataaa 28980 tcacgaactt gcattattca tacattagaa aaaacaacca aaatactaca aaaagtagtc 29040 tttttgagct agccattcta agaataagaa ttcgcttgat ttaaatctcc caattgcctc 29100 tactcaaagt tgtataagta ttgtttagca tgtctcttga agagaatgta aaggaagcga 29160 aaaacgcttt taacatttta cagacattat cagtggaaga ccgtgatgat gcattggata 29220 aaatagttga agaactgcgc ataaaaaagt cagaggttct agctgcaaat gctgaagata 29280 tgaaagcagc taagctcttg gctgaatcag gaaaactaag ttcatcgatg gttaaaagat 29340 tggatctgtc ttcatctgat aaatacgatt ccatggtaca gggtgtttta gatgttaaaa 29400 gtttgcctga tccccttggt cgtgttactt atgctcgtag tcttgacgat ggtttggacc 29460 tttataaagt ctcttgccct gtaggtttat tgctagtcat ttttgaagct agacctgaag 29520 taatcattaa tattacttcc ctggctatca aatctggtaa tgctgttgta cttaaaggag 29580 gcacggaatc agcaaagtct ttcgctgcac tttctaatgt tgttcgctct gccttgggca 29640 aaagtaaggt tccacaggct gctgtgcagc ttgttcagag tcgcgaggag gtatcacaat 29700 tattaaaatt ggatgagtac atagatttgg ttattccccg cggcagcact aatcttgtac 29760 gccatataaa agataacaca aaaattcctg ttttaggtca tgctgcagga ctatgctcca 29820 tgtacgtcca tgaggatgct gatatggaat tggctagtaa acttgttctg gatggaaaaa 29880 ctgattatcc agcagcatgt aatgcaattg aaactttgtt aattaacgaa gctgttttat 29940 cttctcatct tcctaaaatt gctgaaactt taactgaagc aaaagttaca ttaaaatgtg 30000 atcccgcttc tcttaaggtt ttaaaggata tgccaaaagt tagtgctcta gttgaaccat 30060 ctgtcgatca agattacaac actgaattct ctgatttgat tcttgctatt aagactgtac 30120 cttccttaca gtccgcaatg cagcatataa atacacatgg ttctaaacac acggattgca 30180 ttatcacttc tagtgaagca gctgctaaca gattcatggc tggaattgat gcttctggtg 30240 tgtattggaa tgcttcaacc agatttgccg atggttttcg ttatggttac ggtaccgaag 30300 ttggcatcag caccaacaaa attcatgctc gaggaccaat gggtcttgat gggttaacta 30360 tttacaagta ccaacttaga ggaaatggtc aagttgcaag tagttatgga gttggacctg 30420 gcaaacgcgc atttaaacat acccctatta atatagacaa tatttctcag gtttcgaaaa 30480 aataaacaca aaaaagattt gaaaattatg tgaaattgtc aacgttttgg ctagctgcat 30540 tttggataca aatcggttag gctttttttg tttacttgtt tgtctataat atttaaatgg 30600 gagtttcaat aatgtgaagt tattaaatga agagtaaaca ccaaattaaa tagataacta 30660 ttcctgtaga gttcgatcca ccacctttag tttttattac acaaatattt ttatggtgaa 30720 gaacgaattg atgtctccgt ccgtcttttt tgactattca tttcaattca gattctaaaa 30780 tcttcgtaag ctaagattct tggcttcagt tagtagcgtc gtaatattga acagggaggg 30840 ttaggaaatg cgcggagctt atcgcaagcg atcgttgaag ttatataaca aactgcagaa 30900 gtacttgctt ttccagtatc gcagtttaac atatttttat cggattatac cttagctggc 30960 agtagtccta taattaaaaa agcataatag gacttgtcat ttaccatatc cgatttatca 31020 ctgtctcatt tctgttttgc atgtcttgtt aattcatgtt ttaagcgatt gaatttcaat 31080 cttttaacaa tttctttttg ttaattaatt cgttgacctt gtagttgatt ctaattagtg 31140 taaaaattcc atttattgca acatttcttt caatatggat aagaatgatt acttacactt 31200 tgaacggaac ccttcattat ttccgaaatc aactttagac aaagtccaaa agacaaagaa 31260 atatattgaa cattattaca aggtggcagt tgatcatgct gtagagcgca accaaaggta 31320 cgagtagcat tactattcag ggttctagca ttgtttcaca ttcctcaatt agtattccca 31380 tcttatacgt tgatcggata agtatcaaag acgatgcttt tattaattct ttctccgttc 31440 tcaacttcgc gtgttgcagt aaatgcataa tctcgaatgt ttataaaatc ttagacagct 31500 tactcatctt gtttcgaaaa tgttaattaa taatgctagc ttccgtttaa tttactttta 31560 ggtataaata ctaattctct ttagacgtat caatttggag caacgattag caaccgaaag 31620 gggttctgag gagagaaaga ataggcagtt aagagcatct ggtgaaaaag agtctcaatt 31680 tcttcgattt cgtcgtacac ggctttcttt agaagatttt tctaccatca aagttattgg 31740 gaaaggtgca tttggcgagg tacgtttgca taattgttta tgtttttggt atctaattaa 31800 ataggttcgg ttggttcaga aactcgatac gggtaaaatc tatgccatga aatctttgct 31860 taaaactgaa atgttcaaac gtgaccagct ggctcatgtc aaagcagaac gcgacttatt 31920 agttgaatct gactccccat gggtggtgtc attgtattat gcttttcaag attcactgta 31980 tctttacttg attatggagt ttttaccagg cggtgatttg atgaccatgc taataaatta 32040 tgatactttt tcagaagacg ttactcgctt ctacatggct gagtgcgttt tggctatagc 32100 tgatgttcat cgaatgggtt atattcatcg ggatataaaa ccggataaca tactgattga 32160 ccgggatggc catataaaac tttctgattt cggactttcc actggttttt acaagcaaga 32220 tcagagtgcc tcttacatga aacctcgcac aggaaatact gtcaaacgtg gtcaaatggt 32280 agatgctatc tggcttacaa tgtcttccaa ggacaaaatg gctacttgga aaaagaaccg 32340 tagggtgatg gcctatagca ctgtgggtac tcctgattat atcgctccag aaattttctt 32400 gcaacaaggg tatggtcaag attgtgattg gtggagttta ggcgctatca tgttcgagtg 32460 cttaattgga tggcctccct tttgcagtga aaactctcat gaaacttatc gaaaaatcat 32520 caattggcgt gagactctga ctttcccaaa tgatatacat ttaagcatag aagctcgtga 32580 tttgatggac cgacttatga cagattcaga acacagatta ggtcgtggcg gtgctattga 32640 aataatgcaa catcctttct ttactggaat cgattgggat catatacgag aaactgcagc 32700 tccatttatt ccgaatttga aatctattac cgatacacat tatttccctg ttgatgagct 32760 tgaacaagtt cctgaacaac ctgtcacaca acaacctgct tctgttgacc ctcagacgtt 32820 ggaacaaacc aatctggcat tccttgggta cacttacaaa aaattcaatt atttaacgat 32880 gaaaggagca ttgtaagact tctgcaagaa actccatagc tactttgttc attgtccttt 32940 gagcatctaa ctattgttat cgaatttttt ttatcgttaa ttcatgttta ccttctttta 33000 cattatttta gcataactaa taatattacc aattactttt ttttaatgtt gtccctactg 33060 ataaaatctt acatgcactt ctgtaaatat taaattcgtt gcataagaat tccaaattaa 33120 tgcatagatt ttattaggga aaagataaaa aagagtgagt aaaaaacatg tattaataag 33180 tacaacagga tgttaacgcc aagaaaacca accaaaatag taaacaataa ttatgaaatg 33240 cggatcatga cccataacta atagacaatt tctaattgaa cagtgggaac cccagaattt 33300 taacatttta ccagtaaact gactatcgtc taaagaaagt ttcatatact agaattggat 33360 taatgaatta aatgcctaat ctcggctttt taaatattgt tcaatttcat cgacagatgg 33420 tgcattggct tgtaaaaact caccgctctc ttgctcaaac cgagagcgga caaaggcatc 33480 gttttccatt tccacaaata tgtcggtgtc cgtaggacgt aaagtccttc gtaacatttg 33540 ggcaacaata tcaattgtta aagcacaaac cattacaaaa agcatagtaa gccaccatga 33600 aggatttttg ccaaaatgat ggagaaactg tgatctagca agatataaat tcttgtccgg 33660 ataatgctcg cttataaaga tattaaataa aaaccaagcc aaggacgtta aaacaagtac 33720 tattatagaa atgatgttta tgtattgcat ctctataaag accaatttga aattcatgat 33780 aaaaatagca gcagtaaaaa tgagttgacc ataagcgaag atattgttgt cattaagttc 33840 cttcattcca aataaactat acgtaacata gaaaactaag aaagcttgaa tgaaggctat 33900 tgaacaccac ccaaaataca ctcgccaatt gaatgcttca ttgttgattc ccttttgata 33960 aagctccggg acagcgatta cggtactagc acttaagtct ttttcaaaaa tacccagccc 34020 aataacacat aacgaagaaa atagtgtatt aaagcaagta agtccccagc tttcgtaaag 34080 gctctgccct gtgtagccaa caaaaggttg catgatagct tgcatcaaaa agaaaaactg 34140 ttctttatag aaggtaccga gaatatactt tgataatcta acatagctcc atcggccatg 34200 acagaataat aacttaatta ggaatttaaa tcgacctatc gaaaaatccg atgatctagc 34260 agcttgaaga ccctcacgac cagcaattcc aataccaaca tgggcttctt gaatcatagc 34320 aatgtcatta gcaccatcgc caatagctaa agtgacagcc ttttcgagag tattacgcac 34380 tttttgaacc attaacgcct tttgcatggg acttgaccga caacaaataa cagagtccgc 34440 ttcaacggca gtatttatga ataataaaaa cagttcagga tcattctcta tatcggcaag 34500 agtactgcca tctatcacaa taaccagatg agctaaggag ttactgtgaa tagcattcat 34560 gcaagatata agctgatgaa tcatcaaaga agctggatca ttagtaggag gtcgatctaa 34620 tgacagcctt tgaccaccac tgacagtttc atcacttcct tcgactccat ccagagagcc 34680 catgacaaca acagttgaat attcttttat tacgccacaa gaatgaccaa tattgattgc 34740 tgtttccttt ttatcaccag ttagcatcca gaatttgatg cccgctcgga aaagtgaatt 34800 gattgattct ggaacaccaa cttgcaattt atcttcaatt gccgtagctc ccgcaaattc 34860 taaatctttt tcaataaggt ctgcagcttc atctaaaagt tgttgcctgt tggatagact 34920 gtttaacgcc gcatcattca ccaacttcca agactgatac tcgctttcgt caatgaaacg 34980 atgggcatac ataagggttc gtagaccatc agttgcaaat gcatgaacat gctcgaaagt 35040 gttttcaaaa agtttggcat cattgtggtt taaggattca tatattgatc cctcagcttc 35100 ttcttgtttt gatagatact ttttatcttc catcagacgt tcaccgcctg ctaatgaatg 35160 acgtccaaca gctggtcgac gccgggtttc aagaatactg gtgctagcac ggggacgaac 35220 tacacccatt ttctcacgcc tttcatcgag ccaagaagtg acgttgttaa tataatcatt 35280 tctgcgccga gacaaactag gtcttgaagc cgttaaactt ggcctcgaag tgctctggct 35340 attccgaata atcgccttgt ctatttcaat gcttttacga gcctgttcag ctttggttac 35400 tgatttgtcc ttccgtttgg cgaggttgga aagacgaagt cgctttatga tc 35452 //