ID SPAC806 standard; DNA; FUN; 22870 BP. XX AC AL117212; XX SV AL117212.1 XX DT 06-SEP-1999 (Rel. 61, Created) DT 24-NOV-1999 (Rel. 61, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c806. XX KW 40s ribosomal protein s26; conserved hypothetical protein; G-beta repeat; KW glycosyltransferase; low complexity gene-free region; ndk1; KW nucleoside diphosphate kinase; porphobilinogen deaminase; rps26; KW SUR4 family protein; WD domian; WD40. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-22870 RA Wedler H., Duesterhoeft A., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (06-SEP-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and QIAGEN GmbH, Max-Volmer-Str 4, D-40724 Hilden, RL Germany. XX DR GOA; P49740; P49740. DR GOA; Q09899; Q09899. DR GOA; Q9UR34; Q9UR34. DR GOA; Q9UT56; Q9UT56. DR GOA; Q9UT57; Q9UT57. DR SPTREMBL; Q9UR21; Q9UR21. DR SPTREMBL; Q9UR34; Q9UR34. DR SPTREMBL; Q9UT52; Q9UT52. DR SPTREMBL; Q9UT53; Q9UT53. DR SPTREMBL; Q9UT54; Q9UT54. DR SPTREMBL; Q9UT55; Q9UT55. DR SPTREMBL; Q9UT57; Q9UT57. DR SWISS-PROT; P49740; NDK_SCHPO. DR SWISS-PROT; Q09899; HEM3_SCHPO. DR SWISS-PROT; Q9UT56; R26A_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c806 is overlapped by cosmid c24B11, EMBL entry SPAC24B11, CC accession number Z67757 at the 5' end and by cosmid c1639 at the CC 3' end. XX FH Key Location/Qualifiers FH FT source 1..22870 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c806" FT /map="IL" FT misc_feature 1..1756 FT /note="nominal overlap with cosmid SPAC24B11, EM:Z67757 S. FT pombe chromosome 1" FT CDS join(271..407,469..525,556..862) FT /db_xref="SPTREMBL:Q9UR21" FT /note="SPAC806.10, len:166" FT /note="added 3-9-99" FT /gene="SPAC806.10" FT /gene="SPAC24B11.14" FT /product="hypothetical protein" FT /protein_id="CAB61651.1" FT /translation="MFAYNHKTLHVCLRLISLRNCSNTWTFVPYANSNRGLNINQQLKL FT FNRRSKIALSSFIIPTSVDILVKVAGFQRYIVNVEFSNVQSYFRYYNYISLYFVTHSKV FT PLNRLPNSMIPYTVFAHFDIVPYTTYSILTKYRCAQDKEREIVGLINASQSKLRYKFCG FT LRN" FT CDS 1381..2391 FT /db_xref="GOA:Q09899" FT /db_xref="SWISS-PROT:Q09899" FT /label=SPAC806.01 FT /note="SPAC806.01, len:336, SIMILARITY:Candida albicans, FT O94048, porphobilinogen deaminase., (340 aa), fasta scores: FT opt: 898, E():0, (43.9% identity in 319 aa)" FT /gene="SPAC806.01" FT /product="porphobilinogen deaminase." FT /gene="SPAC24B11.13" FT /protein_id="CAB55280.1" FT /translation="MPSCTSFPIGTRKSKLAVIQSEIIREELEKHYPHLEFPIISRDTI FT GDEILSKALFEFKRQLAKSLWTRELEALLVTNQCRILVHSLKDLPSEMPDGMVIACIPK FT RSCPLDAIVFKAGSHYKTVADLPPGSVVGTSSIRRRALLARNFPHLRFVDIRGNVGTRL FT AKLDAPDSQFDCLVLAAAGLFRLGLKDRIAQMLTAPFVYYAVGQGALAVEVRADDKEMI FT EMLKPLQHQETLYACLAERALMKRLQGGCAIPIGVQTDVLAISNSSYRISLLGTVLSAD FT GLRAAFGNAEAVVSSEEEAEELGITVALALLKNGAGPILEEHQRSSDSEESLKNY" FT misc_feature 1399..2319 FT /note="Match to PF01379 Porphobil_deam, Porphobilinogen FT deaminase Score 606.68" FT CDS join(complement(4829..4832),complement(2957..4779)) FT /db_xref="GOA:Q9UT57" FT /db_xref="SPTREMBL:Q9UT57" FT /label=SPAC806.02c FT /note="SPAC806.02c, len:608, SIMILARITY:Saccharomyces FT cerevisiae, YIA3_YEAST, hypothetical 31.9 kd protein in FT bet1-pan1 intergenic region., (293 aa), fasta scores: opt: FT 926, E():0, (55.9% identity in 286 aa)" FT /gene="SPAC806.02c" FT /product="WD domian, G-beta repeat protein" FT /protein_id="CAB55281.1" FT /translation="MDKVQHVILVLSGKGGVGKSSVTTQLALSLHDSKVYSRPLKTGIL FT DIDLTGPSIPRMFGKDAERNRIHQSSAGWVPVYTDETKEIGLMSLGFLLTSKNDSVVWR FT GPKKAAMIRQFISDVSWGELDFLIIDTPPGTGDEHLTIVESLLSETSTVRDVPIDGAVI FT VTTPQGIATLDVQKEIDFCKKASIKILGIVENMSGYICPHCADCTNIFSSGGGLTLSEK FT YKLPFLGSVPIDPKFGEMIENLTPDSNIVHLYSKTEMSKKFSFITNEFLNQLYGPRKLD FT TITTISGHTGRLWSVAAHPMLPLFATSSQDKSVRIYNSNTYNLVHVIDGFHTRSIRRVA FT WRPIERPVLAVASFDSVVSINEKIDDDWECTAALEGHENEVKCIAWSCNGNYLATCSRD FT KSVWIWEATEDDEFDCLAVLQEHTQDVKVVTWHPTEDLLVSGSYDNSICFWRDDGDDWA FT LTCQLQGHTNTVWALAFSPNGNTLASADNDGNVFLWIKISSNEDVATIDSTNILRPALQ FT EEWKQQTSLPHIHKGAVYTISWMNDATLCSAGGDGKIVVYQREKHDEALWHVAYEQDHA FT HGVYEINSLEYLRDDRLLSGGDDGECRVWSFK" FT misc_feature complement(2966..3040) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 20.31" FT misc_feature complement(3302..3397) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 40.01" FT misc_feature complement(3434..3544) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 30.42" FT misc_feature complement(3569..3679) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 47.84" FT misc_feature complement(3830..3943) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 36.97" FT misc_feature complement(4780..4794) FT /note="ttaactttataatag, splice branch and acceptor" FT misc_feature complement(4823..4828) FT /note="gtaaat, splice donor sequence" FT CDS complement(5379..5741) FT /db_xref="GOA:Q9UT56" FT /db_xref="SWISS-PROT:Q9UT56" FT /label=SPAC806.03c FT /note="SPAC806.03c, len:120, SIMILARITY:Neurospora crassa., FT RS26_NEUCR, 40s ribosomal protein s26e, (119 aa), fasta FT scores: opt: 614, E():0, (71.4% identity in 119 aa)" FT /gene="rps26" FT /gene="SPAC806.03c" FT /product="40s ribosomal protein s26" FT /protein_id="CAB55282.1" FT /translation="MTQKRRNCGRNKHGRGHTKFVRCINCSRAVPKDKAIKRWNIRNMV FT ETAAIRDLSEASVYSEYAIPKIYVKLQYCVSCAIHARVVRVRSREGRRIRTPPPRVRYN FT RDGKRVNPAAIAKTAL" FT misc_feature complement(5403..5741) FT /note="Match to PF01283 Ribosomal_S26e, Ribosomal protein FT S26e Score 246.59" FT misc_RNA complement(6775..7574) FT /note="misc RNA associated with spc02611 spc02031, FT possiible celllular RNA as no obvious open reading frame or FT spliced gene in this region" FT CDS join(complement(12643..12667),complement(11461..12541), FT complement(11315..11419),complement(11152..11263)) FT /db_xref="SPTREMBL:Q9UT55" FT /label=SPAC806.04c FT /note="SPAC806.04c, len:429, SIMILARITY:Schizosaccharomyces FT pombe, O94725, hypothetical 50.1 kd protein., (442 aa), FT fasta scores: opt: 1822, E():0, (60.5% identity in 441 aa)" FT /gene="SPAC806.04c" FT /product="conserved hypothetical protein" FT /protein_id="CAB55283.2" FT /translation="MKFLNPPFPYSMTSDPESFGHECFTRRWGIILTGIEKDVSERLSK FT LASTSKDSEVVAQGKPLLNDLEAFKSDIKNDRPLVPLEGEGQDIVEYNEELKQLDNASW FT GNAPWLYSECYYYRRISLIFARYSEWKAYDPFFQQKDSTLKSSRAAVEELAGRYCLLEE FT ELNSIAKKGDSHIAYMVFVEMAQISLWGNATDLSLLTNLSYEELQNLQGQKVVEESQKN FT ILVNDFPTVWSKLKDVHNGRIDFVLDNAGFELYVDLIFAAYLLKAGIAKEIVLHPKDFP FT WFVSDVLPYDIEYLLTNLDTIFPTESVTKFATDLRSFSAKGQLRLRTDPFWTTAHYFGR FT MPDFAAGLLTELEKSDMIFFKGKNILLYLKLTGDCLWPRTTPFGKTLGPIANAINACAL FT RTCKADVVVGLPDGLYEKIAKDLPHWERTGKYAVVEFCPKA" FT misc_feature complement(11264..11277) FT /note="ctaacaggaaatag, splice branch and acceptor" FT misc_feature complement(11309..11314) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(11420..11430) FT /note="ctaaactacag, splice branch and acceptor" FT misc_feature complement(11455..11460) FT /note="gtgctt, splice donor sequence" FT misc_feature complement(12542..12561) FT /note="ttaatgctttgttaacctag, splice branch and acceptor" FT misc_feature complement(12637..12642) FT /note="gtatgt, splice donor sequence" FT misc_feature 13391..13394 FT /note="True l.h end of c1639 S. pombe chromosome 1" FT CDS 14457..14834 FT /db_xref="SPTREMBL:Q9UT54" FT /label=SPAC806.05 FT /note="SPAC806.05, len:125" FT /gene="SPAC806.05" FT /product="very hypothetical protein" FT /protein_id="CAB55284.1" FT /translation="MKKEHASAFRQLWRAGMAAAISTRFPGHRFVIRDLLRNGFRQNNC FT SFYSKEKVENTVIFLEMAASRKSVEHLILKNRLHIQMFRRKAGQRLAHYSTAKERPYFL FT SAYDTYEWCLQRVGTIYNLYL" FT CDS complement(15030..16127) FT /db_xref="SPTREMBL:Q9UT53" FT /label=SPAC806.06c FT /note="SPAC806.06c, len:365, SIMILARITY:Saccharomyces FT cerevisiae, Q06178, chromosome xii cosmid 8543., (401 aa), FT fasta scores: opt: 1344, E():0, (72.1% identity in 272 aa)" FT /gene="SPAC806.06c" FT /product="hypothetical protein" FT /protein_id="CAB55285.1" FT /translation="MNGDNFANSFPKNPLLSRNSSSSNVIQYSDEFSPDEDWLNEHAAK FT EHEERIRRPSVNRAWQKNSTSGGPSVSLEKREADVASLGEVMDLEEVPRGITRQARQLN FT EYIFPKHRFRNHLVDEGKIPLVLVACGSFSPITYLHLRMFEMATDTIQEQTNMELVAGY FT FSPVNDHYKKEGLAPAYHRVRMCELACERTSSWLMVDAWESLQPSYTCTARVLDHFDEE FT INQKRGGITLSDGTKRPCKIMLLAGGDLIASMGEPGVWSDKDLHHILGKFGCCIVERTG FT SDVWAFLLAHDIMFAYRGNILVIKQLIYNDISSTKVRLFIRRGMSIRYLLPNSVIQYIE FT RYALYRDAEPVKTIFYQSPFVRMEP" FT CDS 17654..18109 FT /db_xref="GOA:P49740" FT /db_xref="SWISS-PROT:P49740" FT /label=ndk1 FT /note="SPAC806.07, len:151" FT /gene="ndk1" FT /gene="SPAC806.07" FT /product="nucleoside diphosphate kinase" FT /protein_id="CAB55286.1" FT /translation="MSTEQTFIAVKPDAVQRGLIGYIISKFELKGYKLRALKFLVPSRD FT LVEEHYAEHKGKPFYEKLVGFMASGPVCAMIWEGKQAVKTGRLMLGASNPLDSAPGTIR FT GDYGIDLGRNVCHGSDSIESANREIKLWFQPSEIQVYDRTIEPWIYE" FT misc_feature 17663..18106 FT /note="Match to PF00334 NDK, Nucleoside diphosphate kinases FT Score 335.35" FT CDS complement(18406..20262) FT /db_xref="SPTREMBL:Q9UT52" FT /label=SPAC806.08c FT /note="SPAC806.08c, len:618, SIMILARITY:Neisseria FT meningitidis., Q51281, alpha-2,8-polysialyltransferase, FT (495 aa), fasta scores: opt: 125, E():0.91, (20.5% identity FT in 298 aa)" FT /gene="SPAC806.08c" FT /product="hypothetical protein; possible FT glycosyltransferase" FT /protein_id="CAB55287.1" FT /translation="MGIQGREDLEMPLRNACEVLNRQTVSVKQSILHAQILKLFLELSK FT PPSDIHVPQIPVYKDCNKNEQEAIIQLLTSCEGDHWLMPDWSSMPDDETITEDSEEETF FT NGNANEITIPANIHIPIIEESDNASNNKLCTLFKKSKQPNLDFLQIKPFMFWDSSLNET FT VRISERSIIRDSIYMLIGYPSFFFLKNGSKIETRLSLLPKLHHMSEEILRSIMTELADY FT GSNLEFFRQKLTSPSDSFFKSDDQSTKNEPFLSVVFIYPQIKPHLLSCLKNTHQELIKL FT ETEVYNATKNCTLFQFFQHVKKFVDPLLCFRFAYEKSATNMWDFVKTLEFIYSTRNYSS FT QMFKLYKASAIAMLLWMVNQASQITSSMTIARPLYNILILCKDFPNNFLEKDNIALQLG FT SIVFDQSPTLNNLLVEMEILIRSKILKLGKSLDLSFDFQSLMGEFENLIKQQEEAKKSL FT WSKRFSRFYYGHYVFVNTCHNFFLTLYQSFTEVDENSIFNGVFETLNNDVDDESVIGEK FT EKLILKQKQKCLSEFFVDDIKKLLNEELLNCQKQELPDVMENTYQISTVSGIKNDPLFT FT LDQTCNIIAKLADNLIHPSVPIGSSAYRCRRNLADLLFLIMP" FT misc_feature 20589..22870 FT /note="nominal overlap with cosmid SPAC1639, EM:AL117213 S. FT pombe chromosome 1" FT CDS join(complement(22671..22684),complement(22118..22478), FT complement(21452..22063)) FT /db_xref="GOA:Q9UR34" FT /db_xref="SPTREMBL:Q9UR34" FT /label=SPAC806.09c FT /note="possible incorrect N terminal" FT /note="SPAC806.09c, len:316, SIMILARITY:Saccharomyces FT italicus, AAB87766, v-snare bypass mutant., (347 aa), fasta FT scores: opt: 590, E():0, (46.3% identity in 307 aa)" FT /gene="SPAC806.09c" FT /product="SUR4 family protein" FT /protein_id="CAB55288.1" FT /translation="MLDCWSWLNSLADATFGKRPSSFEFIVNKTRFSSAPVVATIIISY FT YLLILVGGRIMRNRQPIRLQKIFQYYNLTFSIASAILALLIFEQVAPAIYKHGFFFSIC FT NEKAWTQPLVFLYYCAYISKFLELTDTFFLVLRKKPLQFLHCYHHGATAVLVYTQIVGR FT TSISWLIIEINLLVHVTMYYYYYLVAKGIRVPWKKWVTRFQIVQFFADLGFIYFAVYTE FT VAYRLKFYKACMGHCSGHPLAAFCGLATISSYLVLFIVFYHNTYKKNAALKMKAKAAAA FT TKGNSSESSKNADLKRLSKSNASIAEVKCNNIVTNLYPISSGLNNEK" FT misc_feature join(complement(22118..22478),complement(21635..22063)) FT /note="Match to PF01151 GNS1_SUR4, GNS1/SUR4 family Score FT 315.69" FT misc_feature complement(22064..22079) FT /note="ctaacatacgttttag, splice branch and acceptor" FT misc_feature complement(22112..22117) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(22479..22492) FT /note="ctaacaatttttag, splice branch and acceptor" FT misc_feature complement(22665..22670) FT /note="gtatta, splice donor sequence" XX SQ Sequence 22870 BP; 7567 A; 4093 C; 4048 G; 7162 T; 0 other; aaaagcgcga aaattattca gtcaaaccgt gactattcaa gccactcttt tcccagttgt 60 cgcggtgact tgtccatcta gtactggctg tgcagttcct tctcgggaaa agagagttgc 120 taacatatgg gttcaataaa tcaatgaaat ttattagaaa actgtcattt cacactggca 180 ataaaaaaat tgtgacgata agcaattttc ctagtactag agaataattt tcgcgactaa 240 cgcgtaaaca attccaaagg cataacgaca atgtttgcat acaatcacaa aacattgcat 300 gtatgtctgc gtctcatttc gttgaggaat tgctccaaca catggacatt tgtaccatat 360 gcgaactcaa atagggggtt aaatatcaat cagcaattaa agcttttgta tttaaaaatt 420 tggttcaaag attttattag aaaatacaat gactaatcta gtttgcagca atcgccgttc 480 caaaattgct ttgagttctt ttataattcc cacctctgtt gacatgtagt taacaaacat 540 actctaaact tatagcttgg ttaaagttgc tggattccaa cgatacatcg taaatgttga 600 atttagcaac gtgcaatcct actttaggta ttataattat atttcactat attttgttac 660 acattcgaaa gtcccgttaa ataggttacc gaattcaatg ataccttata cagtttttgc 720 acattttgac attgtcccgt atactactta tagtatttta acgaaatatc gttgtgcaca 780 agataaggaa cgtgagatag ttgggcttat caacgcaagt caaagcaaac ttcgctacaa 840 attttgcggg ctgcgcaatt agcgctcttc ttactggtgg aagagtgaaa aaaaaaccgg 900 cgcctttttt taattgagcg aattcttgac aaacgcatcc cgttctctag caacctaaaa 960 atttcttctt gaaggttttc aattctctct ttctaattcc ttttaatctt atgttttaga 1020 aagcctttag ttgtatattt tacttttttt tttctttcaa aacactgaat tttcagcatt 1080 ctcaagtttg ttgagaatat tatactttgg tttctcggta tccgcgttgc gccaaaggct 1140 atttcttcgt ccaaccaagt tgcttccttt ttgatttatt tcatcgagtc tttacacatt 1200 tatatttggc gggtttctca ctccttctgc tcacgcaccc ttgttttttg gtaacatcgt 1260 ttgctttcaa aagtttttgt ttttaaaagt tctgtacatt tgcatctccc ttttccctcg 1320 ttaaaaaaag agatttatta gtttgagcat tgttttgtac attctctaat taattgtaat 1380 atgccatcct gtacttcatt ccccattgga actcgcaagt caaaacttgc tgtaattcaa 1440 tcagaaatta ttcgtgaaga gctcgaaaaa cactaccccc atcttgagtt tccaatcatt 1500 agcagagata ctattggcga tgaaattctc tcaaaggctt tgtttgaatt taagcgtcaa 1560 ctagcaaaat ctttgtggac gcgagaactt gaagctttgc tcgtcactaa ccaatgtcgt 1620 attctcgtac attctttgaa agatttgccc tctgaaatgc cagatggtat ggtgatagcc 1680 tgtataccca aacgtagctg tcctttggat gccatcgtct tcaaggctgg ctcccactat 1740 aaaactgtag ccgatctccc tcctggtagt gttgttggaa ccagcagcat tagacgtcgt 1800 gctcttctcg ctagaaattt ccctcatctt cgtttcgttg acattcgtgg aaacgttgga 1860 accagacttg ctaaacttga tgctcccgac tctcaattcg attgtttagt ccttgctgcc 1920 gctggtctat ttcgtttggg tttaaaagac cgtattgctc aaatgcttac tgctcctttt 1980 gtgtattatg ccgttggaca gggtgctttg gctgttgaag ttcgtgctga tgataaagag 2040 atgattgaga tgttgaagcc gttgcagcat caagaaactt tatatgcttg tttggctgaa 2100 cgtgctttga tgaagcgctt acaaggtggt tgtgctatcc caatcggcgt acaaactgac 2160 gttctcgcta tttccaattc atcatatcgc atctcattac ttggtacggt cctttctgct 2220 gatggtctta gagccgcttt tggcaatgct gaagctgtcg tttcgtcaga agaggaagcc 2280 gaggaactgg gaattacggt tgcgctcgca cttctcaaaa atggcgctgg tcccatttta 2340 gaagagcatc aacggagcag tgatagtgaa gaatctttaa aaaattatta gctttattcc 2400 ttttttattt ttttaaaaaa aaaaaaaaaa aaaaaaaaaa ttgctcactt gaacttttcc 2460 ttactgatta atcaggctgg cttgattgat caaaatatcc ctccttatct ttagttcaaa 2520 aaaggctgaa tcacataccc ctttttctcc gtacattttt gcctccgtcc actgaacaaa 2580 actaccggtt ttaaaaattg tgtgaaattt atccgattta aagatttaat tatttatgaa 2640 aatttattga tatggaccct tcttgaattt tttgccctta actttttgcc gtttctaatt 2700 acttactgga atttagggtt ttatcctaat tcacaaccaa aatagcaatt tttacgacac 2760 tgctttatat tcatttatct ttcgtctcaa gaaattgaga tgctaaatct atataatttg 2820 atgtgtttcg atagttacta taacgtttgt atactatttt attagtaaac ataattttta 2880 taatatgtac ataatacgtg tctgaataat aatccgtact attttaacgt tttgccaaaa 2940 ttttttagtc agccggttac ttaaagctcc aaacgcgaca ttctccgtca tcaccacctg 3000 ataatagtct atcatctctc agatactcga gtgagttgat ttcataaact ccatgggcat 3060 ggtcttgttc ataagcaaca tgccagagtg cttcatcatg tttttcacgc tgatacacaa 3120 cgatctttcc atctccccca gcagaacaaa gagtagcatc attcatccaa ctaatagtat 3180 agactgcacc tttgtgaata tgcggtaatg atgtttgttg tttccattct tcttgtagtg 3240 ctggacgtaa aatatttgtt gaatcaatcg tagcaacatc ttcgttacta gaaattttta 3300 tccataagaa tacattacca tcattatcgg cagaagctaa agtatttcca ttagggctaa 3360 atgccaatgc ccaaaccgtg ttggtatgtc cctgcaattg gcacgttaaa gcccaatcat 3420 ccccatcatc tctccaaaag catatagagt tatcgtagct tccacttact aataggtctt 3480 ctgtaggatg ccatgtgact actttgacat cttgagtgtg ttcttgcaaa actgccaagc 3540 aatcaaactc gtcatcttca gtagcttccc atatccaaac tgatttatca cgagaacagg 3600 tcgcaaggta gtttccattg catgaccatg caatgcattt aacttcattt tcatgacctt 3660 ctaaagctgc ggtacactcc cagtcatcat caattttctc attaatgcta acaacagagt 3720 caaaggaagc gactgctaaa accgggcgct caatcggacg ccaggcaacc ctacgaatgc 3780 tacgcgtgtg aaacccatca attacatgaa caagattata agtgtttgaa ttgtaaatcc 3840 tcacactctt atcctgagag cttgtggcga aaagaggaag catagggtga gccgcaacag 3900 accataacct tccagtgtga ccagatatag ttgttatcgt gtctaattta cgaggaccat 3960 aaagttggtt taaaaattca tttgtaatga aagaaaactt tttagacatc tccgtctttg 4020 aatataaatg aacgatatta gagtcagggg tgagattttc tatcatttca ccaaactttg 4080 gatctatggg gacagaaccc aaaaaaggaa gtttatactt ttcagaaagt gtcaatcctc 4140 ccccacttga gaaaatattt gtacaatcgg cgcaatgagg gcaaatataa ccgctcatat 4200 tttcgacgat accaaggatt ttaatgctag cttttttaca aaagtcaatt tccttctgaa 4260 catccaacgt agcaattccc tgaggagtag ttacaatgac ggcgccatcg atcggtacat 4320 cacgaaccgt tgaagtctca gaaagaagtg attcaactat cgtaagatgc tcatcacctg 4380 tcccaggagg ggtgtcaatg attaagaagt ctaattcacc ccagctgaca tcgctaataa 4440 attgcctaat catagcagct tttttgggtc cccgccatac tacgctatca tttttagaag 4500 tgagtaaaaa accgagggac attaagccaa tttctttagt ttcatctgta tatacgggta 4560 cccatcctgc gctggattga tgaatacgat tccgctcagc atccttgcca aacattctag 4620 gtatggatgg tccggtcaaa tcaatatcaa gaatgcctgt ttttaaagga cgggagtaaa 4680 ctttggagtc atgaagagat aatgcaagtt gagttgtcac tgaagacttg ccaactcctc 4740 cttttcccga taacaccaaa attacatgtt gaactttatc tattataaag ttaattaaat 4800 gaaaaaaaaa cttctcaata tcatttaccc ataacaagca attgtagttt aaaatggaaa 4860 aaggtaaaaa ctctgtgttt acttagtaat acaaaattac tgcagttaag gcggttaaac 4920 gttagaacga ttgagcacct tagttttcgt taaaattata gagtaaaata cattcaatag 4980 agaaagtaag ttggttacat tatcagattt ttttagcaaa actctgaatt tcattttaaa 5040 aaatgatgtg tcctgccaag tgtcaagctt aacaataaat ggcataatga ttcttactaa 5100 tggtttatcg catttcccta atacctggaa actacgttca taaggattga gtaggaaaga 5160 cataaatgca tttccaggac agctaaattg ttttaggaat aatgtgaaat gaatagacta 5220 tgctcttagt atctgttact actgataatg aagagcttat taccacaaaa cgaaatataa 5280 aagagctacg attaaaaata aaaaaactta aaatagtcaa agttcaataa tcttccattg 5340 aatcccatac acacaaagtc tatgaacaac catcaaattt aaagagctgt tttggcaata 5400 gcagcagggt taactctctt gccatcacgg ttatagcgga cacgaggggg aggagtacga 5460 atgcggcgtc cttcacggga acggacacga acaacgcgag cgtgaatagc acatgagaca 5520 cagtattgaa gcttgacata tatcttggga atagcatatt cactataaac agaggcttca 5580 gacaaatcac gaattgcagc agtttcaacc atattacgga tgttccagcg cttgatggcc 5640 ttgtccttgg ggacggcacg gctgcagtta atacatctca caaatttggt atgaccacgg 5700 ccatgcttgt tacgaccaca atttcttctt ttttgagtca tactgttttt tgtagataat 5760 aagcatgtac aatttgttag tttcgactga gagtttgggc cgtgactgtt ttgaaaataa 5820 cgatggaagc tagtacagcg gaatattgtt tagtgtaatg cacagcattc tcaaaaacat 5880 tcgctttaag tcgttaaacg attctatggt tggtgaaaag agagagcgat ttaaaaacag 5940 taataaaccc gaaaattgtt ttgcggttca aagagcaaag gtgtgaatcc tgcatgcttt 6000 gaaaaaattt ggatttactt gctttaagag gaaatatgac tgaattgatg gagttttaaa 6060 ttaccaataa atttcgaaat ttggtagtga tgaaagatta tcttggaatg aaatcagcat 6120 accccagcag tgtagcttta gaatatagtg ggagacatta gaacaggtgc atgagtgcca 6180 aattggcgtt gttggaaagt agaaacctat aaagcgtttt ctaacgacat tttttatagc 6240 ctaaacattc cgtcgttgcg ttctataaat aatctgaacg atgaagtcta ttcaagtaag 6300 cgaaaaatgg ctacgctgaa cgagttgttg tagttaagtg agttaaccga aaactttgca 6360 cgttgaatac tcgtttactt aatttttctt aaaacatgtt gatcgaatag agcctaattc 6420 gcaactatta tgctttgagc gagttaaata aaattatgta tcgtggcacc ggaatgatcg 6480 ggccgaaaga tagagatcaa aatatgtctt gtacaaaaat aatctagcgt aagtactgaa 6540 acaaaataat gctggttaac caagcaaccc atttcatatg tcacggttat gtagtgctac 6600 taccatcaag cgaaaaaaga attgattgct gtttcagaat attgaattat atactccatt 6660 tatgaaagga gcagttctat actaagtttt actcactatt ttatatacag cggattactt 6720 tcacccgacg gactctacgt tcgaaagctt tactttgcaa aaaaatatgt agcatttaaa 6780 aggcgataca aaaagtaaac tgaggatttc atcaaaacgt tatataattc cattactcat 6840 cgcattcaac gatgcaagcg aattcactta atttggctaa acaaacttgg cgaattagcc 6900 ctcgtttaga aggcaatctg attagcatta gaaaatttta gcctaatcct aataagagaa 6960 tttcggatag cgaattacgg aagagtagtt ggtaatggat aaaatcaaac atagcaccaa 7020 aaaacaattt ccagtatgta gttgcgttaa aaaaacagag aaggatagta gttataagta 7080 gattagtaat gcacttttct acgactgtgc aagaatgagg attccatgta gtgggaccat 7140 gagtcggaca gagcatgtaa acaaaccgaa tatagatcaa aaaaaaataa ggattagaaa 7200 actaagaaaa gggaaattaa tgaaatgcgt ttcagaaagc aacatcactt ctttcaacct 7260 tgagggagga aagaaaaagc cagccatcaa atgcgtaaaa tgtaagaatg cacttcacaa 7320 gcaaacatca atgacaagaa gcgatttcaa cgaaagtgta cccgtttatt cgcttagtaa 7380 actggagagc tagtgctctt caccgagaac aaaacccttc ttacagattc cttgagttgg 7440 caccaaatct taggccataa agctaaggtc atatggaaga tgaagatgga tactaagaag 7500 cgaagttggt cttgggtcat aagcatcttg tcaaaaatgt tcgcaattcg tccgtttaca 7560 ctaataaaaa aaaatattcg aggaatataa ccgagacttt atgtgcgatg ctggggtata 7620 tataacccaa taatgtcaag tacaatatcg acttgctgac aatgtgataa aaatgttcca 7680 aaaaataaca cgtaaagaga caaagggtaa gttatcaatc gtttccgtca ccccttaaaa 7740 tttatgtaat ctaagatgta ataagaatag gcgaacatgt aacggaacat tagtttgtgt 7800 gcacaacttg tactggaggg ttttaaagag gaaggccaga tcaaaagatc aaggttaaca 7860 atagtagttt gttcgttaca cgaagagctg gacggctagc aaaacagccg tgaggcgggg 7920 aaacattctt cttgtgcatt ttgcggtatt gtatagcgat gttgtatgaa agtgcgaaaa 7980 aagaaatttg tacaaggaac aaggtacaac tcaaaaatgg agagcgcagt taagttaggc 8040 tgtcaccatg aattaaaaat aatgacacat tcaagtttat ctgaaaagct ataaagcaat 8100 tttctcctta tcaattactc aagtttcaag cgaactaaac aattttctca aaatttttta 8160 attttttttt ttatttcttt taaatttttt tctctttttt ttttaattcc ctttttttcg 8220 tttttcatct tgtaccttcc gtccatttgc tcccttctcc tcctcctttt actttcccct 8280 tgtgctgttc tcatacacta ggcatatttt aaaaatattt acacccctga cttacttggt 8340 cagtaagagt tacaatggta gtactaagag ggaaagaaag taaagtcccg attcgataaa 8400 aaacctgatt tttcatgaga caacatcccc agtttcagcg tttagtagat agcgaatggg 8460 atggttgaaa gttgagggta attgtttgct aaacatgatc gctaaaagga gcacggtatg 8520 cgtgtttcca caattcatga agttcccctg actgtagcgg tttcccttgt ttttaccaat 8580 atctatttct ggtaactatg atttcgcaaa aatgatttca caagatgtat cgtatgcatg 8640 caaaatatag cgccaacgta aagccacgca ctagaacagt tgtgtagttc aacaaaaaac 8700 actataggaa tggatagtta gtagtttaac acatgctgta gggtagttga tactctgccc 8760 attgatgcat agtaataagc agcagcattg taaggttgta acaaaacact gcaaagaccg 8820 aatcgatttc ttatgcttca tggattaaag gtacagtgat gtattagatt tgtttgtaaa 8880 atgtttggcg attgtttgat ttgtttgttt tctaatttaa tttggtttta acatttccat 8940 ttgttctttt ttttttcttt ttgttaatgg tttttctttc tttatgttta tgtttctttt 9000 cttttcattg ctatcgttct tttcggcgtt tcccaaccag aatggttcaa aatgcataca 9060 taattaggtc acgatactcg gcagcttctt ttaaaaaaat cctgctcttc gccattggtg 9120 tcaatatgcc atttctactt gatactattt tagagctacc ggtgttgttt tataccagat 9180 cccgacctac acataacctg attttgcttt cggcttctcc ctgtgtcata gcagcccctt 9240 tgtagaccca acgctcttga caattttgta ttgtacatca agtttgactc cattgcaata 9300 cgtgaatgat aacaaatact tccgataatg gtcacttgca ctgactaata aaccaatgcc 9360 ttaccctaca tagcaagaag gaacaagtgg gcatcgcact ttagcaaatt cttcgtattc 9420 gctacagtag cgtaaagcta agaaaacgac gaaaaaaaat acaaattacg gtaagaaaga 9480 cgaaaaatta aagaaataaa aaaaataaag gaagaaatac gaaaaagaag aacgtaaaga 9540 ataaaagctc ctttgaccgt tccttgtatg cattttttac aaattgtttg atgtattttt 9600 aaacaaaaag aaacgaaaaa atgcctgata aaatgatata aaataaaata aaatagacga 9660 aaaaaaaaat ttaaagcagc aataccctgt tcgctcgtat cttctctttc gctaaatcgt 9720 attgaatttg tattacaagt tacacgcaac tactcgtttt tttattacga caacgatttt 9780 cggtaaataa cttaaatgag tgataacatg tcttttgggg tacaagtagt aaattctaca 9840 ttaggggttt ttttttatcc ttcatttttc aacgactata aaaaggaaat aaagcgggat 9900 ttaaatctct tttttttctc taatttttta ctcatgaatt ttccttcttt cccttcttcc 9960 atgctctctt cttgtaaata gaaaccactc catcccccgt ccaaagaatc aaccaagccg 10020 ctgtatcgcg atttcgaaag taatataggg tccagaattt aaaaaagaac accgcttaca 10080 ctgtcaacct taatagatta gtactcgaac ttttaccgat cgtccccctt gtttcaaaca 10140 aaaaattatc aaatactcgg taacagtgtt cgttaatgtc tttaaatttg caaggtttcg 10200 ttaaagcgct ggttcatttt gcaatgcaag ttcattatac aaaatacatt gtaaatattg 10260 taatgtagct taaaaagttt ttagaacaat caattttttt attctgctaa taccgcataa 10320 cggaatttct tgtattacag aatagattga gcttgcacgt tagctggcac ttttcgaata 10380 aacaaatttc ctattttatt atacgagtgt aacgtaaagt tggatgtatg gtgatataag 10440 ctgttttgtg gttaacaccc ttactctcac tatatgcata caccacagtc cctcattttc 10500 aaaagtaaat cgtacttagc gtagctgaca atttgatagg aagtgctgat taggtagtat 10560 aattcccaat tgcaagcaac caaaattggt agtcaaatat gaatgtgttg caaacattga 10620 gattacaagt gtatgttatt ttttagctaa ctttattttt ttacactact tcactaccag 10680 ggtgttgctt cctagcgtta actgtagctg tacatttctc acaagcaaaa tgtaaacaat 10740 cttaaacatc ttatttaccc gctgcaaata cactccatca ggttgtatgt aaaatgaaaa 10800 ctcgaattat aaccttggta ccaacttata tacgactgta aaaataaaag cttgttgtac 10860 atctgctttt tattttcgta ctcaaaagat attcgttcat tcttgatatc taagtacatt 10920 caattcaaac tattctcaca tggtctctta aaaacattac caatgcctca attgtcgttc 10980 cacataaaat ccgactttat gtacatagcg agtgaactaa acataaaaag tattcaaaaa 11040 gaaatgttag ggtatgatat ttcaaataat agtatgtctt tatactaaag aatgttacaa 11100 taggtttaaa aagataccag gttcttggta aaaagatgaa cgtaaacggt ttcatgcctt 11160 gggacaaaat tcaacgaccg catacttgcc agttcgttcc caatgaggta agtcttttgc 11220 aatcttttca taaagtccat caggaagtcc aacaacaaca tcactatttc ctgttagaaa 11280 ttattcaaat caatatacaa tcaattttac atacgctttg catgtgcgaa gtgcgcaagc 11340 atttatggca tttgcaatgg gtccgagggt ttttccaaat ggtgtagtcc ttggccaaag 11400 gcaatccccg gtcaatttcc tgtagtttag gtcacctatt cgctcattag taaaaagcac 11460 agatatagta aaatgttctt acccttgaaa aaaatcatgt cagacttttc cagttcggta 11520 agcagaccag ctgcaaaatc tggcatacga ccaaaatagt gagcagttgt ccaaaaagga 11580 tcagtacgaa gacgtagttg tcccttcgca gaaaaagagc gaagatctgt agcaaacttt 11640 gttaccgatt cagtaggaaa gattgtgtca aggtttgtga gtaagtactc gatgtcgtag 11700 ggaagcacat cggaaacaaa ccacggaaag tcttttggat gcagtacgat ttccttggca 11760 attcctgctt tcaacaagta ggcggcaaaa ataagatcta cgtaaagttc gaaccccgcg 11820 ttgtccaaaa caaaatcaat acgcccattg tgcacgtctt ttagttttga ccatacggtt 11880 ggaaagtcat taaccagtat attcttctga gattcctcaa caaccttttg gccttgaaga 11940 ttctgcaact cttcataact aagattggtc aaaaggctga gatcggtggc attaccccaa 12000 agagaaattt gtgccatttc aacaaagacc atatacgcaa tgtgcgaatc ccctttctta 12060 gcaatggaat taagttcttc ttctaaaaga cagtatctgc ctgctaattc ctctacagca 12120 gccctacttg atttgagagt cgaatctttc tgttgaaaaa acggatcgta agctttccat 12180 tcagaataac gagcaaatat taaactgata cgacggtaat aataacattc tgagtataac 12240 caaggagcgt ttccccagct cgcattgtca agctgtttta actcttcatt gtactcaaca 12300 atgtcttgac cttcaccttc aagggggact aaaggacgat catttttgat atctgacttg 12360 aacgcttcca agtcgttaag aagaggcttc ccttgtgcaa ccacctcaga atccttagaa 12420 gtcgaagcca atttggatag gcgttcagat acatcttttt caatgccagt taaaataata 12480 ccccatcgac gagtaaagca ttcgtgacca aatgattcag gatcactagt catagaatac 12540 gctaggttaa caaagcatta atatgaggaa tctcaaaaca ataataattt agcaagaaat 12600 ctttattccc taataaagat aaactaatta atttttacat acggaacggt ggatttagaa 12660 acttcatttg gacgattcaa aagagataca aacaatcacc gtggtgttaa gtgaactact 12720 taatatattg aaggatgcaa gcgccaatgc tgagatcgct tgccgatggt gacataatat 12780 tataaaatat aagtaagaat aagatctcgg agaaaactat tactactact tctaatttaa 12840 atctgacatt agttttacgg taagattggg atttgttcga gtcaatatat atatagtata 12900 caaattctac gacggatgaa catagatgaa atcttcaaac gaatatatat ttattattga 12960 atgtactaag aattattaaa tgcattgact agtacaactt ttaagccgac ttccctctga 13020 aattttgtca accatgatta cgacgctacc atcgatttca tcaaacgttt gtagagtagt 13080 ttaatttggg cttattctgt acttagcttt agcagacgat cactcgatgt ctacataaaa 13140 aacgaattga agtaggtttc tccctttttg atatatgact gactatactg aaactgctca 13200 gtactgtctt ggggggttac tcagaacttt tactacatag tagtatcgag ttatatcacg 13260 gattgcgtag caggtacctg cgttgtcgtc ggaagctgcg ttataaaaaa atgtatttta 13320 cttcaaagat taaacatgta tgttatctca cagctaagta cataaatatt ttatttattg 13380 attgattgtt gatcctaaat ttagcgtact aacagaatgg cggcatcgag ttaaatgttt 13440 gaagataata gtaatgtaaa atcaacaaaa tagtataatt gaaaagttcc ttctgttaca 13500 ccgattccat tcagttcagt gctaaaaaaa taaaaaacca aacaatgcta atctgagaaa 13560 attcttttat aaactaatgc aaatgataag ctatggattt aaaagttaac gataaataat 13620 caattgtaaa agtctgaaga aaattcaaaa aaattacaag tgatgagtgt gatgtcaata 13680 tcaataaatc gtaaaaacac gtaaacgcat aaagtaaaaa ctgtaaaata ataaataaaa 13740 ttattaaaaa tgattttata attgatttgc gcacttgcaa tatgtcgaag gtatctaaaa 13800 ttcttttagt ctatcatcac atacgatact attttttaaa atacattttg aagattttta 13860 gagcaaaaat actattaaac atcgaccatt tgcacattcg aaatagttag tgtttatgac 13920 gtttaaaaaa attactacta gcaaaacaaa agtattctat taaaatgctg gtactaagaa 13980 aatgataaga caaaacatat agaaagtaaa ttttttatat aaacacttga tcgtttcatt 14040 aataggctca gttttgaggt gtaaagattt ttacctctta atactccaag cactgacatt 14100 ccaaggtcag tagtaacaaa acagtaaccc aggttactgt tgtttacagt actgaccacc 14160 caaactacgt agtttttcca acttcctgtt gcaactacta atacatcgtg gaagacaaac 14220 actctcaatt ttttttacga gcattttgtt ttcaaaaaaa aaatatagag attatgaatc 14280 accaaaaaag acgcgcataa acgtcagtac cttcagaagt taatcttttt tctaaggatt 14340 aattaaccgc gtccttctat cgctcttacc aacttgcctt gtctattcta tttcacgctg 14400 ctatcataat taaagcctcc ttcaatcgaa gaataaataa aaggtttaat ttaggaatga 14460 agaaagaaca tgcatcagca tttcgacaac tttggagagc aggtatggcc gcggctattt 14520 caactagatt tcctggccat cgatttgtaa tccgggattt gcttcgtaac ggatttcgcc 14580 aaaacaattg ctccttttat tcaaaggaaa aagttgaaaa tacagttata tttttggaaa 14640 tggccgcgag caggaaatct gtagaacact taatactaaa aaatcggttg catattcaaa 14700 tgtttcgtcg taaagctggt caacgccttg cacattattc gacggctaag gaaaggccat 14760 acttcttatc agcgtatgac acctatgaat ggtgtcttca aagggttgga acaatatata 14820 atttatattt ataaaacatt tctattagaa aataatgttc cattggcttt attagaatcc 14880 gaattcttgt caggtataag aaaataaaac tacagagcac agaaatcgtg aaacaagcca 14940 ttcaactaat gtataataga agaacagaaa ataaacactg gattacacaa aattacttat 15000 ggcagaccaa gaaaagtgtc tcataagatt tatggttcca tacgcacaaa cggcgactga 15060 taaaaaatag ttttcacagg ttcagcgtca cgataaaggg cgtatctttc tatgtactgg 15120 ataacggaat tgggtaataa atatcgaatt gacatgccac gacgaataaa caaccgaacc 15180 ttggtagatg agatatcgtt ataaataagt tgctttatga cgaggatatt tccacgatat 15240 gcaaacataa tatcgtgagc taataagaaa gcccagacgt cacttcctgt acgttctacg 15300 atgcagcaac caaatttacc caaaatatga tgaagatctt tgtcggacca cactccaggt 15360 tcacccatgc tcgcaatcaa atcacctcct gccaataaca taattttaca aggtcgttta 15420 gtaccatccg ataatgttat accacctcgt ttctgattta tttcttcatc aaaatgatcc 15480 agtactcgtg ctgtacaagt ataactaggt tgtagacttt cccatgcatc caccataagc 15540 caactagacg tacgttcgca tgccaattcg cacatacgta cacgatgata agctggtgca 15600 aggccttctt ttttgtagtg gtcattaacc ggagaaaagt aaccagcaac taattccata 15660 ttagtctgct cctgaatagt atctgtagcc atttcaaaca ttcgcaagtg tagataggta 15720 ataggagaga aagaaccgca agcgactaat accaaaggga tttttccttc atcaactaaa 15780 tgattccgaa agcgatgttt tggaaatata tactcattta gttgtcgggc ttgtctagtg 15840 attccacgcg gtacttcttc aagatccatc acctctccta aactagcaac gtcagcttca 15900 cgcttctcta aactcacgct ggggcctcca gaggtagagt tcttttgcca tgcacgattg 15960 acgctgggcc tacgaatacg ctcttcgtgc tctttggcag catgttcatt caaccagtct 16020 tcatctggac taaattcgtc tgaatattga ataacgttac tggacgaaga attacgagac 16080 aacaggggat tcttcggaaa tgaatttgca aaattatccc cattcatggt gtgcatatta 16140 aaaaggaatt atgacgagga atggtagaca atcacaatcg ggtcaataaa gaaacagaat 16200 cggtaataat aatacaaaaa tcgatcaaaa ccgcgtataa taagaaaacc ctctttttcc 16260 aaataatgac agacaacaag cgaacaaata ggatcaaaaa tttaaaggct gcgggagaaa 16320 gaggatacta aattctaaag aaaaatgaat agcaaagtag gatatgggaa acgaaggaaa 16380 aaaattaaaa ttacccttta ggtatggaaa aacgataatg tataaccagc gtctaaattt 16440 ggttggaatt acttgtgatt tcttagtgca actctcgaat aacagttgta gaaaaagaat 16500 gaaggataac ctataaaaag aattgaaata aaaaagaaaa gaaaagagga aatttgacga 16560 cgaatcgcaa aagaaacgtt tcccgatcta agcactttta tgtcctcaaa gttggctcaa 16620 aactgatatt cagtgcctct tgtcactaat atcaataata aatattaaag gtaaaccttt 16680 ttgaaaggaa aacggttctt tttaacaacc tacagcttaa actgatattt tttgcgtttt 16740 tggtggtata atggttatgc gtacaatggt gacttaatgt gcagataaac agcgctcgaa 16800 aagaatgtaa ataaaaagtg atgatactac aactgaattg ttaagaaaaa caacttatcc 16860 ctcgtccgtt tatgagtaaa attgtgagac ggctgtcatg ctcattagat agacatataa 16920 tgatttaagc ttatctaaat cccggatttt cgagtatatg ccattacgaa tatacataaa 16980 ttcgcaaaca aggataaaac tctaggaata atcataaaag ccttattcgt atatcaagac 17040 aatgttaaca attatatgta tagggataac taatatatgt acggaaaaaa ccgtttgcat 17100 gaagtgatgt agatgtactt ggaattgtat ctattatcaa ctggttgata atcaaatttt 17160 gcaggtatcc caatactaag ttggtatcaa ttacaagttc ttctaacttt tattagtggt 17220 ttcattcgtt acatggtcct aaaacagtaa gaagttggcg attgggataa taacaaatcc 17280 attatatagt atacaataag ccttacaatc ttttgatttg tggagagttt ttacgtatgt 17340 aaaaaaacaa aactggctta ccgtctacgg gtacgctttg aatgctttgt aatgtgtttg 17400 taaatatgca ttttttgtaa acaataattt acgaccatta agatatctga ggcttggtgc 17460 tctaaaaata taagaaggtg tactataacg attcttatca ttttttatta tttacatctg 17520 tttccgcttt gtttatgcaa tcatattgtg agtgttattt gtccttgctc cgtaatcctt 17580 tatatgggat agtagacggg acagctccca tctactcaac cacctcatat caccgagtat 17640 aagcattttt gatatgtcga cagaacaaac ttttatcgct gtgaaaccgg acgcagttca 17700 gcgaggactg attggataca tcatctcaaa atttgagttg aagggctaca aactacgtgc 17760 tctaaaattt ttagttccta gtcgtgatct tgtggaagaa cattatgccg aacataaagg 17820 aaagcctttt tatgagaaac tcgttggttt catggcatca ggccctgtat gtgccatgat 17880 atgggaaggt aaacaagccg tgaaaactgg tcgcttaatg ttgggcgcca gtaaccctct 17940 ggattctgcc cctggcacta ttcgcggtga ttatggtatc gaccttggta gaaacgtttg 18000 ccatggttct gattccatag aaagcgctaa tcgtgaaatt aaactttggt tccagccttc 18060 ggaaatccaa gtttacgatc gtacaattga accttggatt tacgaatgaa taagaagaag 18120 ttaaagagcc tcttcaaaag gactcgtgtt tgttatgggt gatgcaaact atcagcaaca 18180 cccaaagcaa ataaatatga ctaatgattt tctaccttca ttaaagcaca ctatcatttt 18240 ttttaataga tataggtctt tttcaaatat cattcgttag taaacgacat gaaactagag 18300 aaatcgcatg taagtcagta tggttttact catccaaaag gttactttta tgaaatctat 18360 tgattctata cacgtaatgg taaatattat ggcattttat cgtaatcatg gcattataag 18420 gaataataag tcagccaaat ttcgtctaca tcgataggca gaactaccaa tgggaacaga 18480 aggatgtatg agattgtccg ctagtttcgc tattatatta caggtttggt ccaacgtaaa 18540 taacggatca tttttaattc ctgaaacggt cgaaatttga tatgtatttt ccatgacatc 18600 tggtagctct tgcttttgac aattgagcag ctcttcattt aagagcttct ttatgtcatc 18660 aacaaaaaat tcagataaac atttctgctt ttgctttaaa ataagtttct ctttttcccc 18720 tattacagat tcatcatcaa catcattatt aagcgtttca aaaacgccgt tgaatataga 18780 attttcatca acttcagtaa aagattgata tagtgttagg aaaaaattat gacaggtgtt 18840 gacgaataca taatgcccat aatagaaacg actaaatctt tttgaccata acgacttttt 18900 agcttcttct tgttgtttta ttaaattttc aaactccccc attaaacttt gaaagtcaaa 18960 agataaatcc aaagatttac caagctttaa aattttgctt ctaattaata tttccatttc 19020 cacaagtaaa ttgtttagag ttggagattg gtcaaaaaca atactaccca attggagagc 19080 aatattgtct ttctcaagga aattgttagg aaaatcctta caaaggatta aaatgttata 19140 tagaggcctg gctatagtca tagaactggt aatttgtgag gcttgattaa ccatccacaa 19200 taacattgca atagcagaag ctttatagag cttgaacatt tgtgaagagt aattccttgt 19260 tgaatatatg aactccaatg ttttaacaaa atcccacata ttcgttgctg atttttcgta 19320 agcgaaacga aagcacaata gtggatcaac gaattttttt acatgttgaa aaaattgaaa 19380 aagagtacag ttctttgtag cgttataaac ttctgtttcg agtttaataa gctcttggtg 19440 tgtgtttttt aaacaactta agagatgtgg ttttatttga ggataaatga agacaacaga 19500 gagaaacggc tcattcttgg tactttggtc atcactttta aaaaacgaat cgctaggaga 19560 tgttagtttt tgtcgaaaaa attccaagtt agaaccgtaa tcggcaagtt ctgtcattat 19620 actgcgaaga atctcttcgc tcatgtgatg aagctttggt aataaagaaa gtcgtgtttc 19680 aatttttgaa ccatttttta agaagaaaaa acttggataa cctatcaaca tatatataga 19740 gtcgcgaata atacttcttt cagatattcg gacagtttcg ttcaaactag aatcccaaaa 19800 cataaagggt tttatctgta aaaaatctaa attcggttgc ttgctttttt taaataaagt 19860 acatagctta ttgttagacg cgttgtcaga ctcctcgatg atagggatgt ggatgttggc 19920 tggtatcgta atttcattag catttccatt gaaagtttct tcctcagagt cttctgttat 19980 ggtttcatca tcaggcattg aagaccagtc aggcatcaac cagtggtctc cttcacaact 20040 agttaataac tggattatag cttcttgttc attcttgttg caatctttgt agacgggaat 20100 ttgtgggaca tgtatatctg agggtggttt agataattca aggaaaagtt ttaatatttg 20160 ggcatgcaat atactttgct tgacactaac ggtttgacga ttgagaactt cacaagcgtt 20220 tcgtaaaggc atttctaaat cttcccgacc ttgtataccc attttgtcac agatgctaga 20280 tcaagttagt cttaacattc caacaacaat cggcagatct gctttacgtt acccttttat 20340 atgttctatc atttcatgaa ataccaatgt cgaactaggg acattttgaa tgattttctt 20400 tgaatgtttt aaccattcac tagcaactaa tgaatcatta tgtattagtt cccttaagag 20460 atgctgtagg atttgatccg cacgagacat tgtcatttac agttcttgat aaaacattta 20520 ttaagctttg cctgtattct catatgttct ttattatgtg ctgatattgc taaaatgccg 20580 attaaggagt gtatatttcg tatactatcg cgaatgaagg aaaatttttg tttgacatga 20640 gagaaatgag ttgagtcaat ttatgactga agggggttaa tcattatttg ccgttaagct 20700 gtgtaagtca tttataatag taataaaaaa aaaactaata tattttgttt taaacgtatt 20760 tactgttatt agattaaccg gcgccgctcc ctaactgaaa tagtaagaaa acttcaaaat 20820 aaataatgaa ttccgtatgc tcacttgcaa tgactacaag ttatacagag aaatttacca 20880 accttacaca actgtagtac tgttattaga acgtatattt tcttactaat ttatacccat 20940 ttttcataag ttgtgcatta gtattaccat ggttttttaa tataaaatat taaacaaatg 21000 gacttttaat ctttggaaaa aaagattcag aacattatat tgaagaaaag attttggctc 21060 tgattttttt aattatatta tcacaccatc aagtttgacc ttaagatacc acgaagttaa 21120 caaatctata cttagtagag gtttagctaa aaagtttaga acatgtaaag acgtcgataa 21180 atcttgatta aggaatggga aaaaggattc actggataaa aggtagtaat cgaatataga 21240 caaggatgta aagctaacgg acaattaagt actttcaaaa ttcacaaaat cgtcgcccgt 21300 aagtcactcc aactattaat tggtaattct aaatgcaacg ttaagcagaa caaagaaaaa 21360 aaaggcactt gtagacttta gggctcaata tcaagttata agtaagagca aaatcgggta 21420 attaaaaacc ataagaggta ccacgaaaac attatttttc attgtttaaa cctgaagaaa 21480 taggatacag attagtaact atattattgc atttaacctc ggcaatagaa gcgttacttt 21540 ttgagagacg ctttaagtcc gcatttttag aagattctga tgagttacct tttgttgcag 21600 ctgcagcctt agctttcatt ttgagagcag catttttctt gtaagtgtta tggtaaaaga 21660 cgataaacaa aacaaggtat gaagagattg ttgcgagacc acagaacgcc gctaaaggat 21720 gtcctgagca atggcccata caggctttgt aaaacttcaa ccgatacgca acctccgtgt 21780 atactgcgaa ataaataaaa cctaaatcag caaagaactg aacgatctga aagcgggtga 21840 cccatttctt ccaaggaacc cgaatacctt tggctacaag atagtagtaa taatacatag 21900 taacatgaac caataaattg atttcaatga tcaaccaact gatggaagtt ctgccaacaa 21960 tttgagtata tacaagaacg gcagtggcac catgatggta gcaatgaagg aattgaaggg 22020 gttttttgcg gaggacaagg aaaaaagtat ctgtcaattc aagctaaaac gtatgttaga 22080 atgaaaaaag tatggtcaaa aaacgatgga gacgtacgaa ttttgaaata taagcacagt 22140 agtataaaaa taccagcggt tgagtccatg ctttctcatt gcagatagaa aagaaaaaac 22200 cgtgcttgta aatagcaggg gctacttgtt caaaaatcaa aagtgcaagg atagctgaag 22260 cgatggaaaa agtcaaatta taatattgga aaatcttttg aagacggata ggttgcctat 22320 tacgcataat tctacctccg acaagaatta aaagatagta agatatgatg atggttgcaa 22380 cgaccggggc ggacgaaaag cgggttttgt ttacgataaa ttcaaaggaa gatggccgct 22440 ttccgaatgt ggcatctgcc agggaattta accatgacct aaaaattgtt agtaaaaatc 22500 aacatgaaag cctctcaatc gcattaaaac tagtgaaatt tctattgttc tttcagacgc 22560 ttgctttcat gtttggtagt acttaacgac tacacacaaa agtaacacat gatgtgcctc 22620 aaaaaaagac acaccccaga gatgaacatt ccacaatcaa tcagtaatac cagcaatcca 22680 acatcagcta aaaagtcaca gagtttaact tgagatgaaa aagttttgga tgaaaaaaat 22740 ttcagtaaac ctaacgaaat tttcaccctt gttgattcca cctactctgc cgagtctatc 22800 gggccgtcag cgaaaatgat tggctaagag ctcgctttac gaaccgttaa gcatccacat 22860 ggtggagatc 22870 //