ID SPAC630 standard; DNA; FUN; 32000 BP. XX AC AL109832; XX SV AL109832.1 XX DT 12-AUG-1999 (Rel. 60, Created) DT 25-MAR-2001 (Rel. 67, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c630. XX KW act2; actin-like protein 3; c-4 methyl sterol oxidase; KW conserved hypothetical; gtpase activating protein; protein; KW similar to yeast cell division control protein CDC1; TBC domain; KW tRNA Pro anticodon TGG; Trp-Asp repeat; tuberin; tup1; WD domain; KW WD40 domain. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-32000 RA McDougall R.C., Rajandream M.A., Barrell B.G., Zimmermann W., Wambutt R.; RT ; RL Submitted (12-AUG-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Agowa GmbH, Glienickerweg 185, D-12489 Berlin, RL Germany XX DR GOA; P32390; P32390. DR GOA; Q9UUG8; Q9UUG8. DR GOA; Q9UUG9; Q9UUG9. DR GOA; Q9UUH0; Q9UUH0. DR GOA; Q9UUH3; Q9UUH3. DR GOA; Q9UUH4; Q9UUH4. DR SPTREMBL; Q9C110; Q9C110. DR SPTREMBL; Q9UUG9; Q9UUG9. DR SPTREMBL; Q9UUH0; Q9UUH0. DR SPTREMBL; Q9UUH1; Q9UUH1. DR SPTREMBL; Q9UUH2; Q9UUH2. DR SPTREMBL; Q9UUH3; Q9UUH3. DR SPTREMBL; Q9UUH4; Q9UUH4. DR SPTREMBL; Q9UUH5; Q9UUH5. DR SPTREMBL; Q9UUH6; Q9UUH6. DR SPTREMBL; Q9UUH7; Q9UUH7. DR SPTREMBL; Q9UUH8; Q9UUH8. DR SWISS-PROT; P32390; ARP3_SCHPO. DR SWISS-PROT; Q09866; YAG1_SCHPO. DR SWISS-PROT; Q09867; YAG2_SCHPO. DR SWISS-PROT; Q9UUG8; TU12_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c630 is overlapped at the 5' end by cosmid c12G12 and at CC the 3' end by cosmid c1751. XX FH Key Location/Qualifiers FH FT source 1..32000 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c630" FT /map="IL" FT misc_feature complement(1..3443) FT /note="nominal overlap with cosmid SPAC12G12, EM:Z66568 S. FT pombe chromosome 1" FT CDS join(complement(926..1000),complement(689..821), FT complement(496..626),complement(221..433)) FT /db_xref="SWISS-PROT:Q09867" FT /label=SPAC630.01c FT /note="SPAC630.01c, len:183, SIMILARITY:Saccharomyces FT cerevisiae, YG5P_YEAST, hypothetical 17.9 kd protein in FT yta7-taf145 intergenic region., (152 aa), fasta scores: FT opt: 284, E():4.7e-11, (36.6% identity in 131 aa)" FT /gene="SPAC630.01c" FT /gene="SPAC12G12.02" FT /product="hypothetical protein; similar to yeast YGR272C" FT /protein_id="CAB52723.1" FT /translation="MPKFKGPGLSVLKKKIRDNERLLKKENLPANIRVEHERALLGLQE FT QLSMAQLEHKKQKIFERYKKVRFFERKKAERRIKQLEKSLKDETMDDEKRKQCEKSMRK FT CQIDLMYIKEYPPLTKYVSLYAEGTSEQTEETRNRIWAEMEERFNSGRKHKIPSSGSNR FT VPVQEKSSTGGDLEDEFLQR" FT CDS 1577..4294 FT /db_xref="SWISS-PROT:Q09866" FT /label=SPAC630.02 FT /note="SPAC630.02, len:905, SIMILARITY:Saccharomyces FT cerevisiae, YBK4_YEAST, hypothetical 104.7 kd protein in FT pkc1-rtg3 intergenic region., (925 aa), fasta scores: opt: FT 833, E():0, (26.8% identity in 883 aa)" FT /gene="SPAC630.02" FT /gene="SPAC12G12.01c" FT /product="putative Protein involved in cell shape and cell FT surface morphology by similarity to yeast YBL104C" FT /protein_id="CAB52724.1" FT /translation="MLNRSKKRNGCYFWVNGSSDEIRYVAVKASPKVNWKTHIIWRSLK FT NVKCIDSFHGNNEILGAGSSTGNISLLSVKHPEFQAVVTPGYARPCNSLAFSETEHLVA FT GFAKSRNESSLKLWDLNSLLSDPKSSPLMQSSTLDGVSSVCYKKDTPLLLTGSTSRSVH FT IIDTRQQLDSVSSVNTQYYSNIVVDPFSPNYFAANSYDGDIAIFDTRYFKSDNYLQIIL FT RNENKKPKNPQLFALKYSEWKPGQLAVLSNNSITLRQLLPCVNGNEGSANNSVFVNYEK FT KYPVKPNSQCSGIDFFTPSTAFPTHVQILGVINEQPKLFSVHDEVIPFSFNPYNDLIFS FT FKEKLYPLNSSPFNTLSDVPQFDVSEFVDENSFDSSSSCSSKVFLTTRNNSINSEDSAH FT EVLLSYNRVLGSDIQGTILDRVKKGYQFDSQKNSELVSDLYLKDLWSWIHLSHRQSEES FT LFGDTGDTDFSYQGALGIWFMDTELTSMSDVFEAKESKFLEKKILRLARDVIERLDLDI FT FTSIQTKRPLRQLALLACGLGMSNDDLLLEIRRLIRKNEHVKAAGLALFHGKIENVVRI FT LSSGNELEKTISTAVAGYITSQGLSNFGSDSLWKEMSRNLSTELEDPYLRAIFAYVSNS FT DWRDVLDEVSLSLKDRLGIALRFLPDDDLSNYLCDLCHTTVQSGDPEGLLLTGLTPLGM FT ELLQNYIDHTSDVQTAALIAAFVVPKKFLDKRAEDWTESYRELLNRWKLYRERAKFDIF FT RTELSKNHTGEITRKATEPSIRIICNFCRKPIFPFSNRNECNNLPTPIQRGVSKAGPAK FT HLGKSCPHCGQPLPKCSVCGFSLGDEDVPQKDDFSQKPQNYVKEVNLQKSRFGLWFSFC FT LNCGHGAHASHASEWFSTHTICPVPNCDCECKLK" FT CDS join(4859..4893,4957..4980,5053..5581,5677..6276, FT 6342..6437) FT /db_xref="GOA:P32390" FT /db_xref="SWISS-PROT:P32390" FT /label=act2 FT /note="SPAC630.03, len:427" FT /gene="act2" FT /gene="SPAC630.03" FT /product="actin-like protein 3" FT /protein_id="CAB52725.1" FT /translation="MASFNVPIIMDNGTGYSKLGYAGNDAPSYVFPTVIATRSAGASSG FT PAVSSKPSYMASKGSGHLSSKRATEDLDFFIGNDALKKASAGYSLDYPIRHGQIENWDH FT MERFWQQSLFKYLRCEPEDHYFLLTEPPLNPPENRENTAEIMFESFNCAGLYIAVQAVL FT ALAASWTSSKVTDRSLTGTVVDSGDGVTHIIPVAEGYVIGSSIKTMPLAGRDVTYFVQS FT LLRDRNEPDSSLKTAERIKEECCYVCPDIVKEFSRFDREPDRYLKYASESITGHSTTID FT VGFERFLAPEIFFNPEIASSDFLTPLPELVDNVVQSSPIDVRKGLYKNIVLSGGSTLFK FT NFGNRLQRDLKRIVDERIHRSEMLSGAKSGGVDVNVISHKRQRNAVWFGGSLLAQTPEF FT GSYCHTKADYEEYGASIARRYQIFGNSL" FT misc_feature 5210..5581 FT /note="Match to PF00022 actin, Actin Score 125.95" FT misc_feature 5680..6315 FT /note="Match to PF00022 actin, Actin Score 86.49" FT CDS complement(6809..7309) FT /db_xref="SPTREMBL:Q9UUH8" FT /label=SPAC630.04c FT /note="SPAC630.04c, len:166," FT /gene="SPAC630.04c" FT /product="very hypothetical protein" FT /protein_id="CAB52726.1" FT /translation="MGEEISAIDLVMANDQLVSTSDASDIPYDPYSQFWGKVLVLTFGI FT ICVVFVIFMLHHERIKACRTIISAREQQRTQHSIHRRERSSSGASQQFEHHVRQTDCLP FT LYEPITALNQQYLKTLPTTSTPPPPAIFDENGEFVGDVPSVAGAIERPPSYESLPAPQN FT DEV" FT CDS 8282..10513 FT /db_xref="SPTREMBL:Q9UUH7" FT /label=SPAC630.05 FT /note="SPAC630.05, len:743, SIMILARITY:Yarrowia lipolytica, FT O14440, gtpase activating protein., (730 aa), fasta scores: FT opt: 1191, E():0, (36.7% identity in 735 aa)" FT /gene="SPAC630.05" FT /product="TBC domain protein; putative GTPase activating FT protein of Rab-like GTPase" FT /protein_id="CAB52727.1" FT /translation="MTTLESLDMPEMTEVEDDTVDIHIDNSKVALLFSKSKVFVHPTSK FT MKDNISGYLSLSKSKALGNSSVAGSDILLSWVPDSFLKNRPRDLSVFQNAETLSNGSIR FT EWVEIPQHLDYSFSVRLCSIYSIIFRPPRYGWNYGSIVINLRDSGESLPPLFFHDDECI FT STIEYGKQITRDRFDPFDESGNMFWGGTHLLMQLKKYASLEQSSHESQLYLVNPSPEDT FT VAFQSVELQKVISNNRLNSSSTPPTPRSSSSIFNPFRRALHDLSFTVLERFSRVTNYGK FT SEVDRLMEHKVTKSILPHLPRELQVLLESKRVQKLTEEYDPARMFLARWAEGIVEQSES FT NNSQPVNNAGVWTDAQREEDSSLGPFELVYIEERVKRDDPLSVEQWNSMFNAHGKLQVD FT VHRVLGIIFHGGIQPSLRKEVWPFLLSVYPWDSTSEERRVIYLSLQEEYCTLKRKWYED FT IHKQFNDRWFIEQRNRIEKDVHRTDRQHEYFQIEDLPHPDPQSTFTGTNMNMEMMKDIL FT LTYNEYDTELGYVQGMSDLLAPIYVTFNDNALTFWGMVGLMKRLHFNFLRDQSGMHRQL FT DTLRLLIEFMDPELFAHLEKTDSSNLFCFFRMLLIYFKREFDWEVLLKLWDVLFTNYLS FT YDYHIFVAYAIAERHREVLLNQTSAFDEVLKYFNELSGKLALEPTLICAEQCFYQFKNK FT LALIDRKQMEETNSDEDGSKETDLPTIAPYLRNLLKTSQPQYTPSGKQE" FT misc_feature 9509..10252 FT /note="Match to PF00566 TBC, TBC domain Score 189.56" FT CDS join(complement(11366..11379),complement(11017..11286), FT complement(10893..10974),complement(10615..10815)) FT /db_xref="SPTREMBL:Q9UUH6" FT /label=SPAC630.06c FT /note="SPAC630.06c, len:188," FT /gene="SPAC630.06c" FT /product="hypothetical protein" FT /protein_id="CAB52728.1" FT /translation="METVKVTRKDLLLSPENKEIDSLDDVSALLSQRLSNVFEFSIASE FT EVQSDEVFEDTYPNDDQATFNLFSDVNTVVTKVTEPSIKNSRPLNYYILEDSPERQRQL FT QASVFTYDQLMKAKEEKWPACQKLHKVVSIKKEESKHRRRPSKKRRIRMKLLREKEEQL FT KRQAMAAKRNRFRKNVRKLPNKKKH" FT CDS complement(11975..13267) FT /db_xref="SPTREMBL:Q9UUH5" FT /label=SPAC630.07c FT /note="SPAC630.07c, len:430," FT /gene="SPAC630.07c" FT /product="hypothetical protein" FT /protein_id="CAB52729.1" FT /translation="MDQYRDLPKEDPDTAIEYESGVDEESSLKIEKFRVLIFGKDNSQD FT DLVKSVFNLSKLSEKEKMPFGIKCESEENPNFESYHSKVGKKSCKRFMRWLKANAFAEE FT RDIDCIWYQLNLLDISDEDILCLQYLQGCLIPIVSIIYDFNEFLSPFTKSFLSKIGESN FT TITVKGMPLADVLVFRKKVLKLVSQLSFMTDRKELVYTTCLALEDDDAYTNFVSAQQED FT SSCKFYGGILIGVSHCKYAAAGASYPLPIPASGLLAQKLAIGLLCKDIIKLWNLCPESS FT ILTKEILLELPKASDVAKSIGKMILTSMFVPLWLLKGIWEAPATAKIIIGSIADVTLPV FT QRMYYFIKAGGKLDVPTIHAFYQHYKEFVRPKCLEHIAEITTFNVVTAFSSEAVYQEAI FT RLLDRFRYVSKSSEEDLIVPSFVVNDLITYD" FT CDS complement(14442..15344) FT /db_xref="GOA:Q9UUH4" FT /db_xref="SPTREMBL:Q9UUH4" FT /label=SPAC630.08c FT /note="SPAC630.08c, len:300, SIMILARITY:Saccharomyces FT cerevisiae, ER25_YEAST, c-4 methyl sterol oxidase, (309 FT aa), fasta scores: opt: 1283, E():0, (57.0% identity in 298 FT aa)" FT /gene="SPAC630.08c" FT /product="putative c-4 methyl sterol oxidase" FT /protein_id="CAB52730.1" FT /translation="MNTTSEVIVGTGFQAIRQQLAQMHPELNFVEQLWLAYYKWFDNDV FT VATGLMSFLLHELIYFGRCIPWMIIDAMPYFRRWKIQPKKVPTLAEQWECTRLVLLSHF FT TVELPQIWLFDPMCATFGLSTSVPFPPVTKMIWQITLFFFLEDTWHYWAHRLFHYGIFY FT RFIHKVHHRYSAPFGLSAEYAHPLEIILLGAGTVFVPLMWCYFTHDLHLVTMYIWITLR FT LFQAVDSHAGYDFPWSLNKFLPIWAGADHHDYHHMAFKDNFSSSFRWWDAVLKTDQNYH FT QFKARRLAAKYEAESKKAK" FT CDS 15939..16256 FT /db_xref="SPTREMBL:Q9C110" FT /label=SPAC630.15 FT /note="SPAC630.15 len:110aa" FT /gene="SPAC630.15" FT /product="very hypothetical protein" FT /protein_id="CAC35074.1" FT /translation="MYPKIVARCMIVITKNRESERNVLICYRNVTNVYFSLRILLNRQN FT EGNNCKYKLVFSLYRVSFRRMRLNDRQLSCVESVTNGIGLLCLKQADQVCLFTPTVDSH FT L" FT CDS complement(17151..17984) FT /db_xref="GOA:Q9UUH3" FT /db_xref="SPTREMBL:Q9UUH3" FT /label=SPAC630.09c FT /note="SPAC630.09c, len:277, SIMILARITY:Saccharomyces FT cerevisiae, YG4F_YEAST, hypothetical 33.3 kd protein in FT ade3-ser2 intergenic region., (290 aa), fasta scores: opt: FT 516, E():7e-26, (37.5% identity in 283 aa)" FT /gene="SPAC630.09c" FT /product="Protein with similarity to E. coli putrescine FT transport protein" FT /protein_id="CAB52731.1" FT /translation="MSSLEIIVDKILKFLEKQPKPEGRPFILGISGPQGSGKSTLASAL FT DTELTRKNESVVKFSLDDFYLTHAEQVELAKNNPNNPLVQHRGLAGTHDVTFLNNVLNA FT FVKGSDEEVSIPFYDKSKFGGYGDRGDESQWKKANPKTTTYVIFEGWMVGFEPLDSCML FT SVRARSTRWQNIEGSLLWVNRKLADYQPIFQKIDSLVELEAQEINYVYRWRLQQEHALK FT ARIHKGMSDEEVIEFVNHYMPQYVFYLGTLSNKVHLNPHCLEIILDENRYPVVMH" FT tRNA 19537..19608 FT /note="tRNA Pro anticodon TGG, Cove score 71.02" FT CDS 19932..20744 FT /db_xref="SPTREMBL:Q9UUH2" FT /label=SPAC630.10 FT /note="SPAC630.10, len:270, SIMILARITY:Saccharomyces FT cerevisiae, YBZ1_YEAST, hypothetical 38.5 kd protein in FT ira1-mak5 intergenic region., (337 aa), fasta scores: opt: FT 428, E():5.5e-22, (36.8% identity in 253 aa)" FT /gene="SPAC630.10" FT /product="hypothetical protein; similar to yeast YBR141C;" FT /protein_id="CAB52732.1" FT /translation="MRPIPVKNRIGKNNIDNAKGLKGNKLIRHYHNLLKEKSRLIASSA FT PIEKIKNVESELENIGIDAYQRASRSGQAEGKGGDSSKILIKWIRTTPCFSYCARLKEP FT KDLLEIGSVSVDNKCSTCGLFRVSRIDLHSVHPLIKQQDFLERTPEEGLFTGISCSLVL FT NFAPPELRAKMLLHCTGLLMPPNKEQPPWLFLVLPSPCITNSRYMDEKTLHSIMIQFGF FT ICRQKSISKKIAYYLYSYECFPMKEIDWKKKIVNDGATRNNFFIPCIL" FT CDS join(21183..21199,21255..21273,21350..21422,21505..21571, FT 21675..21730,21777..21913) FT /db_xref="SPTREMBL:Q9UUH1" FT /label=SPAC630.11 FT /note="SPAC630.11, len:122, SIMILARITY:Saccharomyces FT cerevisiae, YJ14_YEAST, hypothetical 15.7 kd protein in FT nup85-ssc1 intergenic region (140 aa), fasta scores: opt: FT 299, E():1.2e-14, (42.3% identity in 130 aa)" FT /gene="SPAC630.11" FT /product="Protein with similarity to Drosophila yakuba NADH FT dehydrogenase chain 5" FT /protein_id="CAB52733.1" FT /translation="MSDLRKIIGLSSVLAVGFMLVILSCALFKNWYPLLIAPLPNLLTK FT KYSTSHDFLQEEDRNLLDFGRFTFGATICTGFALPIVFVNVGLIGTAAATMSCVGGSII FT FLVITLYSQAFVQHEEEF" FT CDS 22954..24222 FT /db_xref="GOA:Q9UUH0" FT /db_xref="SPTREMBL:Q9UUH0" FT /label=SPAC630.12 FT /note="SPAC630.12, len:422, SIMILARITY:Saccharomyces FT cerevisiae, CC1_YEAST, cell division control protein 1., FT (491 aa), fasta scores: opt: 881, E():0, (39.2% identity in FT 352 aa)" FT /gene="SPAC630.12" FT /product="similar to S. cerevisiae cell division control FT protein 1, CC1_YEAST" FT /protein_id="CAB52734.1" FT /translation="MKVGRFLVIIAFCFYVLYLEKIIHTRPHKKCDWRSWEQWESTGNP FT VRIALVADPQLVDDLTYDYPRPLIGIVKWISDQFLRRHWRYLHKSLKPDITFIMGDLMD FT TGREFATEEFKKDYFRMMNVLDPKFTNKLEIYPGNHDIGFGNHAIVKDIQRFESLFGPT FT SRSIDVGNHTLVIVDGIRLSNNVNPQVYQPARDFLKSFETNKDNSRPRILLSHVPLFRP FT AINSCGELREKDDVIKYGLGYQYQNLLLPELSESILKAVEPIAAFAGDDHDYCEVVHNY FT QVDTREAATTEYNVKAFSMTSGILYPGYQLLSLNYPYDNPKADQKSSYQTKLCILPNQI FT QIYVWYGASISIFFALILLRTAIFFFGTDRYSLPLYKTHARRFSLSTTIHLFKKIVRIT FT LSTFISYTWIPFLLFIFLNIFII" FT CDS complement(24327..28346) FT /db_xref="GOA:Q9UUG9" FT /db_xref="SPTREMBL:Q9UUG9" FT /label=SPAC630.13c FT /note="SPAC630.13c, len:1339, FT SIMILARITY:Schizosaccharomyces pombe, YA3B_SCHPO, FT hypothetical 149.2 kd protein c18b11.11 in chromosome i., FT (1294 aa), fasta scores: opt: 620, E():0, (21.2% identity FT in 1289 aa). C-terminal similarity to eg. rat, TSC2_RAT, FT tuberin (tuberous sclerosis 2 homolog protein), (1809 aa), FT fasta scores: opt: 576, E(): 6.2e-31, (34.9% identity in FT 347 aa)" FT /gene="SPAC630.13c" FT /product="putative GTPase activating protein; Rap_GAp FT domain" FT /protein_id="CAB52735.1" FT /translation="MNNKSLLDLSSEPAIKDTDILSYFDANLPFKKRHQIVRSIYHGLK FT YYIYSSTSIIQVWQNIQDFISTKNDNAAFRELVYNLMMRYVSTQKHLSIIERHTFFQTI FT EKDPFQDIAELQLRLKSLSVLTDEGHKISGIENRVGPLLSAWFNQYLQWQSQATELQGK FT DADSKLVHLLFFKSLFKFSTNLVKFQWFLVPEPQMLQLVNSVVQICNHARLEDVVTEVL FT MFFDSMIRYSVIPKASLYDTVLILCSTYISTYSYSKLAQSVIFNLISSPVSNLAFENVF FT NILQYNRSNVNAVRGAVRLMRFLMLQEVKNDAIASITLSSSIEFTEFPLGFNENVDFEI FT LGTVYLFLRTPSILNRLNFLDWHRILNILMYCSQYLPLKASTSKEAFSKTAAFANIYDR FT VLDFLDFEALIPLLQQFQVKLVFFLKDVLPVLKPKIRKKLLRLFETYNLIFPCNQYWVF FT NLEFLLGIYQCKTFDLEDRALLFKLVEDACSVADENSAPILCSKFLFPVIESFSKESDD FT CVVSPVYNMLFFLSVNFQNPGLKDCIDHIFQQLISDTSSVTVRRLATSTLIRLFYYYYD FT LRDAVPIQETLAKMLEILETPSFPFVSRMLCLQFFLRFRANGTSIYICENIDLNEPFKV FT LNVDSELIPAVYPISDSFVNSATVEKHIWERKENDLIKISNHSTEYGKDFVTFPTSSLL FT RFYRKSMATESNWTILMFMITHLADQISNRSMFIGALEEIYNLLDFMCDIVFERVSISA FT EIPSNIRKANIMIPILQNVQMLFVYHDQFSRAQEDELVSVFFAGLQKWNEACHVSIHSL FT MLCCYELPVSIRKQLPAILVTLSRLITKPDLSVHILEFLCSLARLPDLIANFTDADYRQ FT IFAIALKYIQHRDFTKESKDSNDTESILKNSYSSYVLALAYSVLQIWFLSLRLTERKKF FT VPWILRGLKLASEGKPLEDLCLVQYDMMQQFCYSNSDINNQTSTFVDSDVESETWIRGN FT SLFTINVSVNSGFLEAVIRRPTGTTQYTFRNEASLQKFLWEENLTSSKALTRGLLCTPS FT SFVSHFLDPHGISLYNQPLLLPSNDDSVRRAISVFDRIPVIESLKAGLVYVGYQQRREA FT DILANTNPSEDFLTFLNGLGTLFELKTDQKVFAGGLDRENDIDGAFAYCWKDKVTQMVF FT HCTTMMPTNIEHDPGCTLKKRHIGNDFVTIIFNESGLEYDFDTIPSQFNFVNIVITPES FT ESIRRTGRQIKFYKVKALTKYDIDFSLFRRYKIVSSDALPAIVRDVTLNAAVFSHIYHR FT SAGDYVHIWAERLRQLKRLREKFQASVLPEDYNLDEQTKTKLQNGTNFSDFTSYL" FT CDS join(complement(31375..31546),complement(31226..31313), FT complement(30476..30828),complement(29065..30212)) FT /db_xref="GOA:Q9UUG8" FT /db_xref="SWISS-PROT:Q9UUG8" FT /label=tup1 FT /note="SPAC630.14c, len:586. identicle to FT schizosaccharomyces pombe, O14432, TUP1, except we predict FT a different met due to homology. the O14432, TUP1 cDNA is FT truncated." FT /gene="tup1" FT /gene="SPAC630.14c" FT /product="general transcriptional repressor tup1" FT /protein_id="CAB52736.1" FT /translation="MITVRQFTFTIFKFQFMATSNVSSRVNELLEAVKKEFEDICQKTK FT TVEAQKDDFEYKAMISAQINEMALMKQTVMDLEMQQSKVKDRYEEEITSLKAQLEARRK FT EIASGVVPQSSKTKHGRNSVSFGKYGNAGPFNSDNSSKPLILNNGSSGGTPKNLRSPAI FT DSDGTVLAPIQTSNVDLGSQYYSSPHVRPAVGATMAGSAMRTFPSNLPLGHPPPPSDSA FT NSSVTPIAAPLVVNGKVSGNPPYPAEIIPTSNVPNREEKDWTVTSNVPNKEPPISVQLL FT HTLEHTSVICYVRFSADGKFLATGCNRAAMVFNVETGKLITLLQEESSKREGDLYVRSV FT AFSPDGKYLATGVEDQQIRIWDIAQKRVYRLLTGHEQEIYSLDFSKDGKTLVSGSGDRT FT VCLWDVEAGEQKLILHTDDGVTTVMFSPDGQFIAAGSLDKVIRIWTSSGTLVEQLHGHE FT ESVYSVAFSPDGKYLVSGSLDNTIKLWELQCVSNVAPSMYKEGGICKQTFTGHKDFILS FT VTVSPDGKWIISGSKDRTIQFWSPDSPHSQLTLQGHNNSVISVAVSPNGHCFATGSGDL FT RARIWSYEDL" FT misc_feature complement(29080..29181) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 40.28" FT misc_feature complement(29206..29322) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 42.93" FT misc_feature complement(29371..29484) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 54.77" FT misc_feature complement(29494..29598) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 33.14" FT misc_feature complement(29614..29718) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 50.23" FT misc_feature complement(29740..29820) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 34.00" FT intron complement(30213..30475) FT /note="confirmed intron" FT misc_feature 30610..32000 FT /note="nominal overlap with cosmid SPAC1751, EM:AL133154 S. FT pombe chromosome 1" FT intron complement(30829..31225) FT /note="confirmed intron" FT intron complement(31314..31374) FT /note="confirmed intron" XX SQ Sequence 32000 BP; 10411 A; 5588 C; 5801 G; 10200 T; 0 other; gatccaaaag cttctctccc acaagttcta tttttggtac cctagcaaat cccattgcaa 60 tatgacatag aaaaaattta aataaacttg cataaaaaga ataccttgct cgataactca 120 tatggaaact tcacaacctt tattaaaaag aatgaatcat attattacag tttcgtctat 180 ttaatccctt tatttccaaa acctcaatcc aagttttcat ttatctttgc aaaaattcat 240 cttccaaatc accaccagtt gaactttttt cctgtacagg aaccctgttg gaacctgaag 300 atggtatttt gtgttttctg ccactattaa agcgttcttc catctcggcc caaatgcgat 360 ttcgagtttc ttcggtctgt tcagatgtgc cttctgcgta gagtgaaaca tactttgtta 420 aaggggggta ttcctaaata ggttagtatc ttagccaagt tgatagttga aatgaagtcg 480 aaaatacaaa catactttaa tatacataag atcaatttga catttacgca tcgatttctc 540 acactgcttg cgtttctcat catccatagt ttcatccttc aaagattttt ccaattgttt 600 aatacgtcgt tctgcttttt tacgttctga gaaaatcagt aagcaagttc actgaacaaa 660 aaatgctgtt tttatatatg tttcatacca aaaaatcgaa cttttttgta tctttcaaaa 720 atcttttgct ttttatgctc taactgtgcc atagacaact gctcttgtag acccaaaaga 780 gctcgttcat gttcaacacg aatgtttgca ggcaaattct ccttaaagga agttagtttt 840 cttattcatt aacataaaaa ggaaggtaat atttattaca cactgaaacc gcagatgttt 900 ttaaaccagc aaaaaaatta cacacctttt tcaataatct ctcattgtcg cgaatttttt 960 tcttcagcac agaaagtcca gggcccttaa attttggcat gctaaaacgc tcaataaaat 1020 agataaatag aaattcaaac cataaacaat tagttctggt gaagaacagt agtaaactta 1080 aaggactgca atttttacag ctgctaggtt ctcaagtgac acgttacttt tatatataag 1140 tttaagctgg taattatgat taaaatattt gattcactca cacttattca aggtagattt 1200 atatgttgta cttgtggagt gatttaaaag cttagacttt caacagtaca tcaaagaatc 1260 gcttgttcga caccgaagtc accctagaga ttaaaaagta tgcaaaagat agttaatcta 1320 gcaaccggtc tgtattttaa tactactatt gttaagagaa tcatcaatag caaaaagaaa 1380 acctttgaat ttgacagcct cttttcagtc cgttgttaag gcatttctgt tagctatcgt 1440 taagcaaatt agtgctaaac gttatgtttg acgagtggtt gagattgaag aacgcttcga 1500 tcaagctctg tttaatgttt atgcagtatt ttgggcgttt ctggtaaagc ctaattgtca 1560 aatttctctt tagagaatgt taaatagaag taaaaagagg aatggctgtt atttttgggt 1620 taacggctcc tcagatgaga ttcgatatgt cgccgtcaaa gcttccccta aagtaaattg 1680 gaaaactcac attatttgga gatcattgaa aaatgttaaa tgtatagact cttttcacgg 1740 aaacaatgaa atattgggtg ctggttcttc taccggaaat atatcattgc tttctgttaa 1800 gcatccagaa tttcaagcag tagtaacacc tggatatgct cgcccttgca atagtttggc 1860 attttctgaa actgaacatc ttgttgctgg atttgcaaaa tctcgaaacg agtcttcctt 1920 gaagttatgg gacttgaatt cattactgtc tgacccgaag agtagtccct taatgcagtc 1980 ttctactcta gacggagttt cttccgtttg ttataagaaa gacactcctc ttttgcttac 2040 cggatcaact tcgcgttctg tccatataat tgatactagg cagcaactag actcagtttc 2100 ttccgtcaat acgcaatatt atagtaatat agttgttgat ccattttctc ctaactattt 2160 tgccgcaaat tcttatgatg gtgacattgc gatttttgat actcgatact tcaaatccga 2220 taattattta caaattattt tacggaacga aaataaaaag cccaaaaatc cacaattatt 2280 tgcactgaaa tattctgaat ggaaacctgg acaattggct gttttgtcaa acaattcgat 2340 tacacttcgt caattattgc cttgtgtcaa tggaaatgaa ggatccgcaa ataattctgt 2400 ctttgtaaat tatgagaaga aatatcctgt taaaccaaat tcacaatgtt ctggcattga 2460 tttttttact ccttctacag cctttccaac tcatgttcaa attttgggtg tcataaacga 2520 acaaccgaaa cttttttctg tccatgatga ggtcattccc ttttcattta acccttataa 2580 tgatttgata ttttccttca aagaaaaact gtatccttta aactcttcac catttaacac 2640 actttctgat gtcccacaat ttgatgtcag cgaatttgtc gatgaaaact ctttcgattc 2700 ctcgtcttct tgttcctcca aagtctttct aacgacaaga aacaactcaa tcaattcaga 2760 ggattccgct catgaagtat tgctttccta taaccgcgtc cttggatctg atattcaagg 2820 gacaatacta gatcgcgtca aaaagggcta ccaatttgat tcccaaaaaa actcagaatt 2880 agtttctgat ttatacttaa aagatctatg gtcttggatt cacttaagcc atagacaatc 2940 agaagaatca ctgtttggag acacaggaga tacagatttc agctatcaag gtgcactagg 3000 tatttggttt atggatactg aattgactag catgtccgat gtttttgaag caaaagaaag 3060 caaattttta gaaaaaaaaa ttttaagact tgctagagat gttattgaga gacttgattt 3120 agatatattt acgtctatcc aaactaaaag gcctttacgc caactcgctt tacttgcctg 3180 tggattagga atgtcaaatg atgacttgtt gttggaaatt agaagactga ttcgcaagaa 3240 tgagcatgta aaagccgctg ggttagcact tttccacgga aaaattgaaa acgtagtccg 3300 tatattatca agtgggaatg agctggagaa gaccatatcc acagcagttg ccggatacat 3360 tacatcgcaa ggcttaagta actttggaag tgactcattg tggaaagaaa tgtctcgtaa 3420 cttaagtaca gaattggaag atccatactt acgtgcaata tttgcgtatg tttccaactc 3480 cgattggaga gatgtattag atgaagtttc tctctcatta aaagatcgtc ttggaattgc 3540 tcttcgcttt ttaccagatg acgatttgag taattatttg tgcgatttat gtcacactac 3600 agtgcaatca ggcgacccag aaggcctgtt acttacaggt ttaactcctt tgggaatgga 3660 acttctgcag aactacattg atcatacaag cgatgttcaa actgctgcat tgattgctgc 3720 atttgtggta cctaagaaat ttctggataa acgtgcagag gattggactg aaagttatag 3780 agagcttcta aaccgctgga aactttaccg tgagcgtgca aagtttgata tctttcggac 3840 agaactctca aaaaatcaca caggagaaat aaccagaaag gctacagagc catctatacg 3900 cattatctgc aatttttgta gaaaaccaat ttttcctttc tccaatagga atgaatgtaa 3960 taatttacca acgccaattc aacgaggtgt cagtaaagca ggcccagcaa aacacttggg 4020 aaaaagttgt cctcattgcg gacagcctct tccaaagtgc tctgtatgtg ggttttcttt 4080 aggagatgaa gatgttcctc agaaagatga cttttctcaa aaacctcaaa actatgtcaa 4140 agaagttaat cttcagaaat ctagatttgg gttatggttt agcttttgtc taaattgtgg 4200 ccatggagct cacgcatctc atgcttcaga atggttttca actcatacaa tatgtccggt 4260 tcctaactgt gattgtgaat gcaaactgaa atagaaattg caaatgagag cattaattaa 4320 tagcattaaa ataacagttt atggtttggt tcacaagtaa taattgctac atgagtgaat 4380 ataaaatcca tgattacagc ttaaaaatgt ttaaggctaa gaggtttaaa gcataaggtc 4440 tttaatacta tgatttgttt aaaaattcga catagctatc tacatttgta attgtttgat 4500 aataccaacg tggttagttt tattactgaa aagggattaa cgcaagatcg ttaatattta 4560 attttctagt agcaagaagc gtcttctagc ttagcaactt ggtaatttta accggtggta 4620 ctggtattga agaaatacat atttaatttt ttgtgtaaat taatttggcc ttagtaaaga 4680 tatccaaagt gggttgtata cgggcattcg catttaacgt aatcggctca tctcgtaaat 4740 taccatatgt ttcccgttaa cccacgtaat tcgacatcgg tgaccgttgc gagacgatat 4800 taagagtttc aactggaacc aacttctctt tcgcttacct tttcataaaa taatagcaat 4860 ggcttcgttt aatgttccca ttataatgga caagtaagta ttgatgtagc gaagttaaat 4920 tgttcgtgaa tatcagttac taactttatt tgttagcggt accggctata gcaagcttgg 4980 gtatgtgtaa tagtcgtttt aggatgttat tatctctctt ttgagcattt attaacagta 5040 atttaatttc agctatgctg ggaacgatgc tccttcttat gtattcccca ctgttattgc 5100 gacgcgttct gcgggtgctt cttcagggcc ggctgtttca tcaaagcctt cttacatggc 5160 ctcgaaaggc agtgggcatc tctcaagcaa aagggcaact gaggacttgg acttttttat 5220 tggaaacgat gcattgaaaa aggcgtctgc tggatattct ttggactatc ctatccgtca 5280 tggacaaata gaaaattggg accatatgga gcgtttttgg caacagtctc tctttaaata 5340 tttacgttgt gaaccagagg accattattt tcttttgacc gaacctcctt tgaatccacc 5400 tgaaaaccgt gaaaatactg cagagattat gtttgagtcg ttcaactgtg caggactcta 5460 cattgctgtt caagcggttt tggctcttgc cgcctcttgg acatcttcaa aagttactga 5520 tcgttcgttg accggtactg ttgttgactc tggtgatggc gttactcata ttattcctgt 5580 tgtatgtata aaaaatctaa tacgagctta gataaacagt tttgaacatt aaatgcatat 5640 atatatgccc gaattttact aactgataaa ccttaggccg aaggatatgt tatcggctct 5700 tccattaaga caatgccact tgctggtcgt gatgttacgt actttgttca atccttatta 5760 cgtgaccgca atgaacctga ttcaagtctc aaaactgctg aaagaattaa agaggaatgt 5820 tgctacgttt gtccggacat tgttaaggag tttagtagat ttgatcgtga gcccgaccgt 5880 tatttaaaat atgcatctga atcaattact ggacactcta ctactattga tgtaggattt 5940 gaacgcttcc tcgcacctga aatatttttt aatcctgaga ttgcttcttc cgattttttg 6000 acccctcttc cggaacttgt ggacaacgtc gtacagagct cacccattga cgttcgtaaa 6060 ggcctttata aaaacattgt cctttctggt ggtagtactt tgtttaagaa ctttggcaac 6120 cgcttacaaa gagatctcaa gcggattgtt gacgagcgta ttcaccgcag tgaaatgctc 6180 tccggtgcta aaagtggtgg tgtagacgtt aatgttatct cccataaacg tcaacgaaat 6240 gcggtttggt ttggcggcag tttactagca caaacggtat gtcattatct tatgtttgta 6300 tattttttag tttacccgta gagatttact gacatgttta gcctgaattc ggatcctatt 6360 gccataccaa agcagattac gaagaatatg gtgcttccat tgctcgtagg taccaaattt 6420 ttggaaattc tctttaatga aatatatcat gagttttgcg tctataggat ttactgatta 6480 aaatgaaaag tttaatggag caggcattag ccttagaaga aatagacttg aggtttgcta 6540 tgtttccagg ctttttcatt gagcaatatc aaataagatg tatataatta acttgtccaa 6600 ataataatga tgagaaccat gagaataata atatagtgat tactaataac gtaaaaggag 6660 aaaaaaaaag aaaacggatg aaaccgatgg gttccgcctg ataaatactt tattattcaa 6720 gaacgatgga taaaatggaa agtgtacaag tactcaacga atttgttgag agaaagcaga 6780 agcaatcaag tagtcatcat aaaaaaaact aaacttcatc attttgcgga gcaggtaatg 6840 attcataaga aggtgggcgt tcaattgcac cggcaacaga tggaacgtcg ccgacaaatt 6900 caccattttc atcaaatatt gcgggcgggg gaggtgtgct tgtggtgggt aaagttttca 6960 agtactgctg gttaagagca gtaataggtt cataaagagg gaggcaatca gtctgtcgaa 7020 catgatgttc gaattgttgt gatgctccgg aagaagagcg ctctctcctg tgaattgagt 7080 gttgtgttct ctgctgttcc cgtgcagaaa ttatggttcg acacgcttta attctttcat 7140 gatgcaacat aaatatgaca aacacaacgc agattatccc aaacgttaat accaacactt 7200 ttccccagaa ctgggagtaa gggtcatacg ggatatctga agcatctgat gttgaaacca 7260 attgatcatt agccatcaca aggtctatgg ctgatatttc ttcccccatt tttgtttgat 7320 tataattttg aacgtgtagt gttcccagta gaatttcaat tgccacggct caattaagac 7380 tgaacgtcag aaatttacaa caatccagtg aactcactga tatagcaagg caattattat 7440 tcttccaatt taattttact caattacttt gaggtttgta aaagtgaggt taaaactgtt 7500 gtaaaaaaca aagataagcc ataaagcttc ccgtctcctt ccccagagtc tggatttttt 7560 tgcgatattt acggtacgat acggcagtca ccggaagcat ccaaaagctg accatgtata 7620 attatatgct ttgatttcag atcatccgtg cgcctatgta ttaactgtgt tgtataaatt 7680 tatttcacaa tcggcaaatt agttatgaat taattacttt tggtatttct gctcttggtt 7740 atgcagcgta agtgaatttg acgatctccg tttaaataat gagctactac gaggtgatcg 7800 ttaaattgta aacaaaagat tggtttagta tgtcgcttga atggaaactg caaagttttt 7860 aattagagat tcatctgttt catctaaatc taaagcaatt aatttttcat ctcttcagtt 7920 gttcttttta atagagtagt tgaggtggat aaatgtttat tcaaattttt gttattcgga 7980 ttatttcgta caggagaagc tatcacaaag gtcaaagcca taatatattt aataatttat 8040 tgtaaagaga aaaataatta tcagaaaatt caacatattc aatttaaggt caagcacact 8100 ggtgtccgct aatgcgttta ctatactaag ccctctgctt gcttacgtgc atcgccacta 8160 cctagctata ggtgcttgtt gcaagacaac aaagtctcgt acctttgcag cgttaaacga 8220 tttttagcaa tttcctcttt ctttaaaatt tggaattaac tgattgtttt ctattcctgt 8280 aatgacaacg ctggaatctc tggatatgcc agagatgaca gaggtcgaag atgatacagt 8340 cgacatacac atcgacaatt cgaaggtcgc tctccttttc tctaaaagca aggtgtttgt 8400 tcatcccaca tcgaaaatga aggataacat atctggctat ttgtccttgt ctaagtcaaa 8460 ggcgctagga aattcatcag tggccggaag cgatattttg ttatcatggg ttcctgattc 8520 gtttttaaaa aatcgtccca gggatctttc cgtatttcaa aatgcggaaa ccctttcaaa 8580 cggttctatt agagaatggg tagagattcc tcagcatttg gactactctt tttctgtacg 8640 attgtgcagc atttattcaa ttatatttcg acctcctaga tatggatgga attatggtag 8700 tatagtgatt aatttgagag acagtggtga gagcctccct cctctttttt ttcatgatga 8760 tgaatgtatt agtactattg agtatggcaa gcaaattacc agagatcgtt ttgatccctt 8820 cgatgaatca ggaaatatgt tctggggtgg aacgcatttg ttgatgcaat taaagaaata 8880 cgcttctctt gaacagtcct cacatgaatc acaactgtac cttgttaatc cttctcctga 8940 ggatactgtg gcatttcaat cagttgaact tcaaaaagtc atttctaata atcgacttaa 9000 ctccagttct acccctccta cgcctaggag ctcatcatct atctttaatc cttttcgccg 9060 tgcccttcat gatttgtcat tcactgtgct tgagcggttt agtcgggtca ctaactacgg 9120 caaatcagaa gttgacagac tcatggagca taaagttacc aagtctatat tgccacacct 9180 tccacgtgag cttcaagtgc ttcttgagtc aaagagagtt caaaaattaa ctgaagaata 9240 tgatccagcc cgaatgtttt tggctcgttg ggctgagggt attgtagagc aatctgagag 9300 taacaattct caacctgtca ataatgcggg tgtttggact gatgcacagc gtgaagaaga 9360 ttcgtcgctg ggtccatttg aactagtgta catagaagag agggtgaagc gtgatgatcc 9420 attgtctgtt gagcaatgga attcaatgtt taatgctcat gggaaattac aggttgacgt 9480 tcatagagtt cttggaataa tttttcatgg gggtatacaa ccctctcttc gtaaggaagt 9540 ttggcctttt ttgctctctg tttacccttg ggattcaact agtgaagaaa gacgcgttat 9600 ttatttgagc cttcaagaag aatattgcac tttgaagaga aagtggtatg aagatattca 9660 taaacaattt aacgatcgtt ggtttattga gcaacgaaat cgaattgaga aagacgtaca 9720 tcgtacagat agacaacatg aatacttcca aattgaggat cttcctcatc ctgaccctca 9780 atcaacgttt accggaacca atatgaatat ggaaatgatg aaagatatcc ttctgactta 9840 taacgaatat gatacggagc tggggtatgt ccaaggaatg tccgatttac ttgctcctat 9900 ttatgtcact tttaatgata atgccttaac tttttgggga atggttggtt taatgaaacg 9960 tcttcatttt aattttttgc gtgatcaatc cggaatgcat cgacaacttg atactttacg 10020 acttcttatt gaatttatgg atcctgaact atttgctcac ctcgaaaaaa ctgactcctc 10080 taatttgttt tgctttttta gaatgctgct aatatatttt aaacgagagt ttgattggga 10140 agttttgttg aagctttggg atgtcttatt tacaaattat ctatcttatg actatcatat 10200 cttcgtggca tatgcgattg ctgagagaca tcgtgaggtg cttttgaatc aaactagcgc 10260 ttttgacgaa gtattaaaat atttcaacga actttcagga aaactagctt tagagcctac 10320 actaatctgt gcagagcaat gcttttatca atttaagaat aaattagctt taattgatag 10380 aaaacaaatg gaggaaacca actcggatga agatggcagt aaagaaactg atttacccac 10440 aattgcacca taccttcgca atctattaaa aacaagccag ccacaataca cgccgagtgg 10500 taagcaagaa tgaatagcat attgattatc aatgattatc atgctagtgt tggttgactg 10560 catttaatac atttatgtga attttagacg atagaagtat acttattttc gattctaatg 10620 ctttttctta tttggcagtt tccggacatt ttttctgaaa cgatttcttt ttgcagccat 10680 tgcttgtcgc tttagctgct cttccttttc gcgtaacaat ttcattctta ttcttctttt 10740 cttactgggt cgcctgcgat gtttactctc ttcttttttt atagatacga ctttatgaag 10800 cttctggcat gccggcttat tgcacgaatg attagcattt tttcttttga atatttaaga 10860 ttttaattgc aaaatataat aacattacat acccattttt cctctttagc tttcattaac 10920 tgatcataag tgaaaacact cgcttgtaat tgcctttgtc tttcaggaga atctctttat 10980 aagttagaaa atagcagtgt atagctcttt acatactcga gtatataata gttaagcggc 11040 ctagagttct ttatagaagg ctctgtaact ttggtgacaa ctgtgtttac atcggaaaag 11100 agattgaatg tagcttgatc atcatttgga tatgtatctt caaaaacttc gtcagattga 11160 acttcctcag atgcgattga aaattcgaat acgtttgaca agcgttgtga tagcaaggct 11220 gatacgtcgt caagtgaatc tatttcttta ttttccggtg aaagaagcaa gtcttttctg 11280 gtaactctaa attacattaa taaataaata atttatttgc aacagtaatg ttgcgcaagg 11340 tctatgtaaa gtaataattg cttactttac ggtttccatg atcgcttaac catataatta 11400 agcaaattga cagaaactct gtctacgtta tgtaaataga taaaaacttt aatgaaataa 11460 aagaatataa tgaaatcagt aagatacaaa tgtttactta caccattcaa gctaaaactt 11520 ttttccgtca gtgaacctat ttatcagcag taagttgtat agcgatacaa tttttttatg 11580 atcgctataa tgaaaatgca gatgataatt taatttattc aaaagaaata aagctaacgt 11640 ctaaatataa atcaatgaaa gcattaagca aagatcacgc ttatattcta attgtatatt 11700 aagagttcac gctgttttgt agtagaaata gttaattaat ttttttacta gattattcaa 11760 tatcaaatct tattatatcg attatcggat ggttgaagat cataaagaaa cggcaatttt 11820 attaaagcaa aaagaaaaca tagattttac agtcaccaaa atctgcgagg aatagggtaa 11880 ggaaaccaat ttagtatcca tcaatatcaa taattgagtt catatattca tttcataagt 11940 tgtgcaaagc aaagttaatt cgtaaaaatc caaattaatc gtatgtaatt aggtcattaa 12000 caacaaaact gggtactatt aaatcttctt ctgatgattt cgatacataa cgaaaccggt 12060 ctaataaacg aatagcctcc tgatatacag cttccgatga aaaagctgta acgacattga 12120 aagttgtgat ttctgctata tgctcaagac attttggtct aacaaattct ttgtaatgtt 12180 ggtaaaaagc gtgaatagta ggcacatcaa gcttgcctcc tgctttaata aaataataca 12240 tcctttgaac aggtaatgta acatcagcaa tgcttcctat aattatttta gcagtagctg 12300 gagcctccca aatacccttc aaaagccaaa gaggtacaaa catggaggta agaatcattt 12360 tcccaattga tttggcaaca tctgaagcct tggggagctc taataggatt tctttagtaa 12420 ggatagaaga ttccggacat aaattccata gtttgatgat atctttgcac agaaggccaa 12480 tagcaagctt ctgagcaagc aggccagacg ccggtatggg taagggatat gaagcacctg 12540 cagcagcata cttgcaatga gatacgccaa tgagtattcc tccataaaac ttacagctcg 12600 aatcctcttg ctgagccgaa acgaagttgg tataagcatc gtcgtcctcg agtgccaaac 12660 atgtcgtgta gaccagttct tttctatcgg tcataaagga taattgggat actaatttaa 12720 gaactttttt gcgaaatact agtacatctg ctaaaggcat acctttaacg gtaatagtgt 12780 tggattcacc gattttgctt agaaaagatt tggtgaatgg ggagaggaat tcattgaaat 12840 cataaattat acttacgata gggatcaaac agccctggag gtactgtaaa cacaaaatgt 12900 cttcatctga aatatcaagc aagtttagtt gataccatat gcaatcaatg tcgcgttctt 12960 ctgcaaacgc attcgctttc aaccaacgca tgaacctttt gcatgatttc ttcccgactt 13020 tagaatgata actttcaaaa ttagggtttt cttcgctttc acactttata ccgaatggca 13080 ttttttcttt ttcagataat tttgagaggt taaagacaga ttttaccaga tcatcttggc 13140 tattgtcttt tccaaaaatt aaaacccgaa atttttcaat ttttaaactt gattcttcat 13200 cgacaccgct ctcgtactct atagcagtat cgggatcttc tttgggcaaa tcacgatatt 13260 gatccattgg tctcgtaatg tattagcatc aagtcgtcag taaactgtga atctaactag 13320 caaacagtgc gaaaaggtat ctattaaaat atatgtttaa aatgaaagta catccttctc 13380 taaattaggt ggttaaagaa tggagtttaa tcaatttctt tctggtgtga tcattaagca 13440 aaatgaagac actcactata aaggcttaaa aaagtttgga attgacaaaa tgttatgact 13500 gggcttacta gtttgctttg ttaaatagct ttattttaac tatgatggca tcgaatgcaa 13560 tagtgtagat agataggtgc ttatacatta ttttggataa tgaaattttg atgattgtaa 13620 gtattgcaag tcggtaactc aacaattacg aaatgtttta gactgtttga agaaagttga 13680 aagatggatt taattcaaag atcataaaga tttaatggca gaggtattat ctttatgatc 13740 ttaaaagcgc tgtagcacaa catcctaaac aatcgaaaat cattctacaa aagcgactct 13800 gaacattatt tgttaagaac aaaaaatttt tttacgactt tgcgtcacaa aaaaacgtag 13860 ctttcttctt ttatcatatg gtgaaaagaa tgcaaaatac aaattatctg gactgatcaa 13920 agtgcttaaa gcaaaagata gcaccgacgt atttgcaaca tatggaaatc ttcaacaaga 13980 atgtcgaaag tgaaaacgac tacaggatta tgctacataa caaaagtacg aaatgacaac 14040 tcatacctat acaactaatc aaatgaaaat agtctaacat tgtaaaagaa aaagaacgac 14100 aaaatttttt gatattaaag aataaagggt aggaaaggat agaattgacg cgatatctag 14160 accattgtaa aaccttacaa tagctaaaat cttagtatgc aaataaacca agagattgaa 14220 atcaaagata ataaaaaacc acataaattc gttatgacca agagggggat ttcaaaagca 14280 agaaacaata tagcgtaatg tcaagcagcg aaagttaaaa aaaaccaaat gaaaaagcat 14340 tcaaagagag aacgttcaaa gacataaaat caacaaaccg agtctgtata gataaatgct 14400 accacagaaa ccgaaaccaa ttttgatgaa agcgcaccaa tttatttagc ctttttgctt 14460 tcagcctcat atttggcagc aagacgacgg gctttgaatt gatggtagtt ctgatcagtc 14520 ttaaggacag catcccacca gcggaaagag ctagagaagt tatccttgaa agccatatgg 14580 tgataatcgt ggtgatcagc acctgcccaa atgggaagga atttgttcaa agaccaaggg 14640 aagtcgtagc cagcatgaga atcgactgct tggaatagac gaagggtgat ccaaatatac 14700 atggtgacca agtgcaaatc atgggtgaag taacaccaca tcaaaggaac aaagacggta 14760 ccggcaccca aaaggatgat ctccaatgga tgagcatatt cagcagaaag accaaaaggt 14820 gcactgtagc ggtggtgaac tttgtgaatg aaacgataga aaataccata gtggaaaagg 14880 cgatgagccc agtaatgcca agtgtcttcg aggaagaaga acagggtaat ttgccaaatc 14940 attttagtga caggagggaa gggaacagag gtagaaagac caaaggtagc gcacataggg 15000 tcaaagagcc agatttgagg aagctccacg gtaaaatgag aaagaagaac caagcgtgtg 15060 cactcccatt gttcagcaag ggtgggaact ttcttgggtt ggattttcca gcggcggaag 15120 tagggcatgg catcgataat catccaagga atgcaacgac cgaagtagat aagttcgtga 15180 agaaggaagg acataaggcc agtagcaaca acatcgttgt caaaccactt atagtaagcg 15240 agccataatt gctcgacaaa atttagttcg ggatgcattt gagcaagttg ttggcggatg 15300 gcttgaaagc ctgtgccaac aataacttca gaagtagtat tcataatgac aggtctaaag 15360 gggaaggaat aaaaagacta caaaaacgtg aacgtaaaaa taaacgaggc cgagaaaaat 15420 aaaagataaa caaaacaaca actagatgaa aatagacgta gaaacactct tcctttgata 15480 aatgaaagag ctaatcaatt caactgagtg cgcagataca ctcacttcta ctgtagacgg 15540 ggcgcaaaga cagatatagc gccaacaaaa aaagccgaca ataacaagga caaaaaaatt 15600 ctacttgtcc gtatactgtg cagttactat tcttagcttg caattaaaga atgcaaggta 15660 ctagtacgat cgttcaccta aagggttact ttatgtgata gttgtaaagg aaacgatatc 15720 ttggcttata tatcgctggt gatttaccaa acagcgaaaa aatcatctga ggtaaactca 15780 cgccattttt tggcatacaa attttatcag cggattagcc atttacagtt caaagattac 15840 gatttatata ttttaaatgg ctctcaaaac tctttagata tttggacttc ttttcacata 15900 tacctatttt cgtttgtcca tagaggcaag gcttggaaat gtacccaaag atagtggcga 15960 ggtgcatgat agtgataact aaaaataggg aatcagaacg caatgtgtta atttgttatc 16020 gaaatgtaac gaatgtttat ttttcgctcc gaattctcct aaatcggcaa aatgaaggga 16080 ataattgcaa gtataagctt gtattttctc tgtatcgagt atctttcaga cggatgaggc 16140 tgaatgatcg gcaactctct tgcgtagaaa gcgttactaa cgggatcggt ttactgtgcc 16200 ttaaacaagc cgaccaagtt tgtctattta ctccgacggt tgattcccat ctgtgattgc 16260 atcttttatc cttcatattg agtcatcctg aatggtccgc tcaaagggaa cttcgtctat 16320 ctcggtgcgc ttaataaacg cttgttttcg tgatgaacaa accctttgca gtgaacccat 16380 gaccttaatc gtttcaactt gacatacggc caatgagcgt agtgacatta aataagagta 16440 tcgagttttt tcttcttttt ccacttttca aattaagcta aattcaatgt ttcgttgagt 16500 ttctgtatgt aacagcatat gaatggcatg tggtattgga aacaatgtga aagcggatat 16560 caatattgca ttcgtttaaa ttactggttt ttatgacctc acatacaatc attaaaacgg 16620 ctttcgacta catgcgacca acaggctttc accattgttt tgtttttatt catttccttt 16680 tacctactgc tattttatta ctcgctggta tcattatttc atgactactg gcaataagca 16740 tatcaacaac cgcccaccga atatcacatt attaaaaatg cttgatattt ctagttaaca 16800 aacttgtact taaagcgtca caaccgaagc aaaccaataa atagcgaaaa aggctattcg 16860 ccatgggagc atttattaga aacggtgaat tgtcgaacgt gatagcagcg cattgttaag 16920 ttttacaaag atggtttaca tcgtctaaaa gcagcttgct agaaaaagca tacaacaata 16980 tcataaaaag cttttgtcgg tcaaaccttg atgggttact tcaaaagaaa gttggaatta 17040 aagaaaaagt agaggtaaaa actttgttca aggaaagggg ggagcgtaaa aagtattcca 17100 aagtacagga acgctataca atcatgggat ttaaatctta gacaaataca tcaatgcata 17160 acaacaggat atcggttctc atcaagtatg atttccaaac agtgtggatt cagatgtact 17220 ttattagata aggtaccaag ataaaagaca tattggggca tataatgatt aacaaattca 17280 atgacttctt catcactcat acccttgtgg atccgagctt tcaaagcatg ctcttgctgc 17340 agtctccatc tgtaaacata gtttatctct tgtgcctcta gttccaccaa agagtcaatt 17400 ttttgaaaga taggctgata atctgcaagc tttctgttta cccacagtaa acttccttca 17460 atattttgcc aacgtgttga tcgtgctcgg acagacagca tgcaagaatc gagcggctca 17520 aacccaacca tccatccttc aaaaattaca taggtagttg ttttaggatt tgcctttttc 17580 cattgggatt catctcccct atctccgtag ccaccaaact tggatttatc gtaaaaaggg 17640 atagatacct cctcatcgct tcccttaaca aatgcattta aaacattatt taaaaatgtg 17700 acatcatggg ttccagctaa accacgatgt tgaacaagag gattattggg attatttttg 17760 gccaattcaa cttgttctgc gtgcgtgagg taaaagtcgt caagtgagaa cttcacaact 17820 gattcgttct tccttgttaa ttcggtatct aaagcacttg ccagtgtgct tttaccagat 17880 ccttgagggc cggaaattcc aagaataaaa ggacgacctt caggttttgg ctgcttttcc 17940 aggaatttta aaattttgtc gacaatgatt tccaacgaac tcatattcca cttctatata 18000 aaatttttaa attaaataca aaacctagct tccccttaaa aacgacttaa taacataagt 18060 ataggaaaga cgtaggacta atactcgaaa tgtgaaagaa agcgaggtgc tgtagctata 18120 tgaaaattca atgttaagta ccacagtgac tagatacttt cgtaacgact accagtaaag 18180 gactacaaac acaaaaagct ttttaaaagg ctaaagtcgt tatgcaatgg ttggatttta 18240 ccaacaaagt tttgttacgg gatgttgtat cactaacatt ccgttacgtc tcatttgtgc 18300 caatatactg aatgcttgcg taaactctgt aatacttgga aacggcttca ctgcgcctca 18360 ctatttggaa agttgtaacg ctgtaaatgt tttgttttta cctataagta aatagaagat 18420 acataataaa atttggtgat gctctggatt ttcagggata atagaatttc tgtagttata 18480 ttttctacaa tgacggctaa cttttaaatt gtttaatctt gatgccatgc agtatagctc 18540 aaatgctgaa gaatttaggt aatatgcatt ttatactttg tctttaaatt gtcatacttg 18600 tctcttgcga cttttatagc taaataataa tattccagtg ctaacgtatg tgttttttct 18660 atagtaatcc aaaaaaaaca cgcaatttat tgtgtcagta aataaagtaa cttgtaaaaa 18720 taagtttagc tgaaatgtac aacaatcagt cccccatcca atgcgatagc agccgcagtt 18780 acaaatatta tttatattta attattacat tttgtttaca ggtacataat gtttgttaac 18840 actttttgta cgtttaatta aactaaaagt atttattttt ttaacatata ctctaaaaaa 18900 ttaatttact caagtttgag ttatcaagaa aatttaatct acaataatta tttttgaagc 18960 acttatttgt tttaatagta tatagtctgg tgaaacaatt agaattcgtc tgtaagtagt 19020 aaaaatacaa aaatgtttct atggttttca tatcataaat acttacactt cacccgttta 19080 acttaaaaac ttaaggtaat ccgtagtaca ccaaattctt ttcttttctt tttttatttt 19140 tttttatttt ttaaaatgta ttttatttaa gaaataataa ataaagtccc ttatccaatt 19200 ccactagata taaatcgtta gtttagaatt taccaaaata cttttcaata gctgtcgtat 19260 atacatattt atacacattt attactttct tttaaaaata acttatatca attatatcgt 19320 aacgtaactg atgagtggaa tcatttaaaa caatttaaga gagaagttga tattggctgt 19380 ttatttatcc gaattttttt atgttatagt tctaccatat ttggcggttg ttttctttat 19440 tttgattatt ttttaaaaac aattgaaaaa gtttagttaa taatcaagta aatctaataa 19500 ctatatatac agttttcaaa gcacaatatc aactgaggct tcgtggtgta gtggtagcat 19560 acttcgtttg ggtcgaagtg gtcaggggtt cgatccccct cgaagcccaa agcctttaaa 19620 tttttgtttc aaatataaaa aaagttgatt tgtgcttgta aagtacaaac cgtataaaaa 19680 aaggaaaccc gtttaatatt ctgtgtaatg gttaaagggt tgcataaatt accgctcttt 19740 aattacatat taagaattta tcatacattg tccaagctct tcttgtgctg aatttttata 19800 agtaacgcga cactacttct ttcatcgtaa aaacttttca agtaattagg aaactacatt 19860 tatgaaccat ttactgtaaa tacaattata ttttcatctg ggagattaac aaatatttta 19920 tcactatttg aatgcgtccc attccagtga agaatcgcat tggaaaaaac aacattgata 19980 atgcaaaggg actgaagggg aataagctta ttcgtcatta tcataacctg ttaaaagaga 20040 aatctcgact tattgcgtca agtgctccga ttgaaaaaat aaaaaatgtg gaaagtgaac 20100 tcgaaaatat aggtattgat gcttaccaac gagctagtcg atccggtcaa gcggaaggaa 20160 aaggagggga ttcaagtaaa atattgataa aatggattcg gacaactccc tgtttttcgt 20220 attgcgcacg tcttaaggag ccgaaagatt tgttggaaat tggcagtgtt tctgttgaca 20280 acaaatgttc aacttgtgga cttttccgag tttcaaggat tgatttgcat tctgttcatc 20340 ccttgattaa acaacaggac tttcttgaaa gaactcctga agaaggactt tttactggga 20400 taagttgttc acttgtgctg aattttgcac ctccagaact ccgagctaaa atgttattac 20460 attgtacagg attgttaatg cctcctaata aagaacagcc tccttggtta tttttggttt 20520 tgccttcgcc ttgcataaca aattctcggt acatggatga aaaaacatta cactcaatta 20580 tgatacagtt tggatttatc tgtcgtcaaa agtctatatc gaaaaaaata gcctactatt 20640 tatattctta cgagtgtttt cctatgaaag aaatagactg gaaaaagaag atcgttaatg 20700 atggggcaac taggaataat ttcttcattc cctgtatact ctaattaaga tatttgtcaa 20760 tacaaaattt attttactag tatctcaaag ttaaattaat gaaatgaatg ctttttgtcg 20820 gttatcctct tgcttttttt taattgtatt gttaatgtca attactagcc tttacttacg 20880 tagctacaaa gtacgttttt cagagtttgt tcgtatgcga tactttacta atgagccgaa 20940 agctcgatca ttggtgtaaa aaatagtaac aagtcatttt cgttatatgt ctttttaaac 21000 ttatttgcca agtttacaaa tcttgtgcac cgctctgtgt tctatgcata cagaacacat 21060 ctgtataacg taatggagcg tacccttttt aggtgaagta gctggtaatc atcgaagtct 21120 ctcttctcaa aagcagtaaa ctttagcttg cagtatatat tcgtgaacga tagtaattaa 21180 atatgtccga cctcaggaag taagtaattt ttgttaatat gaaaaagcaa aggttaacgt 21240 ttgtcaccaa ttagaattat cggtctttct tcggtatgca tcgctcaatg actcctactc 21300 gagctagaca tcaattccat tttaaacgag tctaacttat attattaagg tcctggcagt 21360 aggatttatg ctggtgatcc tgtcttgtgc tttattcaag aattggtatc cactgctaat 21420 tggtatgatt ttgtcaaccg ttgagaacta tttcatttac attgcttacg aattactaat 21480 gaatagtcat tccattcatt ttagctcctc ttcctaatct ccttacgaaa aaatactcga 21540 caagccatga ctttttacaa gaggaagaca ggtatggaaa tataataatg ttggttgttc 21600 tggggaaatt atttcaacca taattgttat ttttcattat tatttgtaag gagctctact 21660 aacgtttact aaagaaatct tcttgacttt ggtcgattta cattcggtgc aaccatctgt 21720 accgggtttg gtatgtattt ataactgaat gagaccttta tgctaattta taatagcttt 21780 acccatagta tttgttaatg tcggattaat tggtactgct gctgctacaa tgagttgcgt 21840 tggtggatct attatatttc ttgttattac tttatattct caagcttttg ttcaacacga 21900 agaagaattt taatatttat ttacttgatt attaattgct cgtttaatgc ttgtcttttc 21960 tcatactttg ctctcccctt agtatttctt agtgtctgaa gagttataag gattcgtgtt 22020 aatattaaca gttttcttga atttttcaga tgttcaattt cacggagcat tgctttcaag 22080 tcttgattct tgaagtatgt taacgaaata tcttactcat tggcttttga ctatagttaa 22140 cctgtttctc tcgtttttgg gtgcttttta ctataagaga aatactggaa tttttcagtt 22200 tcttggaatt tttatattga ttaaatatct agtcattgtc aaaatagata ttacgttaca 22260 tatttaaact agtaattagt aaggccgaag tatcacgaaa agtcactttt atgataaaat 22320 taaactatag aatgtattcg tctatatgaa ttctggacct taatagtttt ctatatgagt 22380 aatttaaaat aagattgtac ctttctctga ttaggcgaca tttagaactt atcctctcta 22440 gctacgtgct tctgaagatt gttcaatatc gacctaaata caaagcaatt aatgagtcag 22500 tttataaatt aaatcaatta gaaggtgaat attacttgtt gagtgaaaat agtgggtatt 22560 caatcaagaa attgagcacc gcaaagcttc atattaagat tctctacatg aggccagtcg 22620 cttcttgagc caaaggtcct tcagttttcc aaacttcaca atttttgaag tctttactaa 22680 caaggtttat ctagaagaaa aatacacctg tttcaaagtc atactaagaa caggaataat 22740 aaatttaact aatcattagg gtctagtgtc atttctccaa catttcggtt ttattgtaaa 22800 cgtggagttt cattagattg ctttgaaatt actcgacctt tattctgcat cgataaatta 22860 gaacgtagtg tatatacttg gcatactatc tcgatttact attcttactt tcttagagcg 22920 tgcattttta atagaagaaa agaataactg aagatgaaag taggtcgttt tttagtcata 22980 attgcttttt gtttttatgt tctttatctc gagaaaatta ttcatacaag gccacataaa 23040 aagtgcgatt ggcggtcttg ggagcaatgg gagagtactg ggaatccagt aaggattgca 23100 ttggttgcgg atcctcaatt agttgacgat ttgacttatg attatcctcg acctttaatt 23160 ggaatcgtta aatggatttc cgaccagttt cttcgtcggc attggcgtta tcttcataaa 23220 tcactgaagc cagatattac tttcataatg ggcgatttga tggacacagg tagagaattc 23280 gcaactgaag aatttaaaaa agattatttc agaatgatga acgtccttga cccaaaattc 23340 accaataaat tggaaatcta ccctggcaat catgatattg gatttggtaa tcacgctatt 23400 gttaaggata ttcaaagatt tgaatctctt tttggtccaa catctcgatc aatagacgtt 23460 ggcaatcata cactggttat tgtagatgga attcgtttat caaacaacgt caatccccaa 23520 gtttatcaac cggctagaga cttcttaaaa agctttgaaa caaataagga caactcgaga 23580 cctaggatcc ttctatctca cgttcctttg tttcgccctg ccatcaattc ttgcggggag 23640 cttcgtgaaa aagatgatgt tatcaaatat ggtttgggat atcagtatca aaacttgctt 23700 ttgccagaac tttccgagtc tattttaaaa gctgttgaac caattgccgc atttgctgga 23760 gacgatcacg attattgcga agttgtgcat aattaccagg tggatactcg agaagcagcc 23820 accacggaat ataatgtgaa ggcattttct atgaccagcg gcatactata tccgggatat 23880 caacttctct cattgaacta tccttatgac aaccctaaag ccgatcaaaa aagttcttat 23940 cagacaaagt tatgcattct tcctaaccaa attcaaattt atgtttggta tggtgcttct 24000 atatccatct tttttgctct tatattattg aggactgcta tctttttttt tggaactgac 24060 cgttatagcc tcccacttta caaaactcat gcacgccgat tttcattgtc aacaacaatt 24120 catttgttta aaaaaattgt gcgcataacc ctttctacat tcatctcata tacatggata 24180 ccgtttcttt tattcatctt ccttaacatc ttcattatct gatctataaa taatatttaa 24240 gattaaataa aaaaaattaa ttaatgatgg caaggcacaa tcgtaatcaa tcttttaatt 24300 taggactttt tatatgccct tatggctcat aaataactag taaagtccga aaaattcgtg 24360 ccattttgaa gcttggtctt tgtttgctcg tcgagattgt agtcttctgg taaaactgaa 24420 gcttgaaatt tttcgcgtaa tctttttaac tgtcgtaatc tttcagccca tatatgaaca 24480 taatcaccag cactgcgatg atatatatgt gaaaaaacgg cagcgttcag agttacatca 24540 cgaacaattg ccggtaatgc atcgcttgaa acaattttgt aacgacggaa taagctaaag 24600 tcaatatcat atttggtcaa cgctttaact ttataaaatt taatttgacg ccctgttctt 24660 ctgatagatt cggattcagg ggtaataaca atgttcacaa agttgaactg actaggaatt 24720 gtatcaaagt cgtactctaa accagattcg ttgaatataa tagtaacaaa gtcatttcca 24780 atatgacgct tctttaatgt gcacccaggg tcatgttcta tattagttgg catcattgta 24840 gtgcaatgga acaccatttg ggtaacttta tctttccaac aatacgcaaa cgcaccgtct 24900 atatcatttt ccctatctaa accaccagcg aaaacttttt gatctgtttt taattcgaat 24960 aatgtgccca gaccgttaag aaaagtaagg aaatcttcag aaggatttgt atttgccaat 25020 atgtctgctt ctcgacgctg ttggtaccca acgtacacaa gaccagcctt cagtgattca 25080 attacaggaa tacggtcaaa aacacttata gccctacgca cagaatcatc attagaggga 25140 agcagaagag gctgattgta taaagaaata ccatgtggat ccaagaaatg agagacaaag 25200 ctgctaggag tacacaaaag ccccctcgta agagcctttg aacttgtgag attttcctcc 25260 cataaaaact tttgcagact tgcttcattt cgaaaagtat actgcgtagt acctgtcggg 25320 cgacgaatga cagcttctaa gaatccagag tttaccgaca cgtttatcgt aaagagtgaa 25380 ttaccacgaa tccaagtttc actttccacg tctgagtcaa caaaagtaga tgtttggtta 25440 ttgatgtcgg aattagaata gcaaaattgt tgcatcatgt catattgaac aagacataaa 25500 tcttccaatg gtttaccttc agaagcaagc ttcagtccac gcaatatcca aggtacgaat 25560 tttttacgct cagttaatct taacgaaaga aaccatattt gtaacacgct ataggctaga 25620 gctagaacgt atgatgagta agagtttttt aatatgctct ccgtatcatt tgaatctttc 25680 gactccttag tgaaatctct gtgctgaatg tatttcaaag caattgcaaa aatttgtcta 25740 tagtcagcat ccgtaaagtt tgcaataaga tcaggtaatc ttgctaaact gcataaaaat 25800 tctaaaatgt gaacgctcaa atcaggtttg gtgattaacc ttgacaaagt gactaaaatt 25860 gcaggtaact gctttcgaat tgaaacgggt aattcataac agcataacat aagtgaatga 25920 atagaaacat gacatgcttc gttccatttt tgcaaccctg caaaaaaaac gctgactaat 25980 tcatcttcct gagccctgct gaattgatca tgataaacaa aaagcatttg tacgttttgc 26040 aagattggta tcatgatgtt ggccttacga atattagaag gaatttcagc agatatagaa 26100 actctttcaa aaacgatatc acacataaaa tcaagtaaat tatagatttc ttctaatgcg 26160 ccgataaaca tactcctatt acttatttga tcagcaaggt gggtaatcat gaacataagg 26220 atagtccagt tagactctgt agccatggat tttcgataaa accttaacaa ggaagacgtt 26280 gggaacgtta caaagtcctt gccatattct gtagaatgat ttgaaatttt aatcaaatcg 26340 ttttcttttc gttcccaaat atgcttttct actgttgctg agttaacaaa agaatcagaa 26400 atgggataaa ctgcaggaat cagttctgaa tcaacgttta agactttgaa gggttcattc 26460 aaatctatat tctcacatat ataaatagac gtcccatttg ctcgaaatcg aagaaagaat 26520 tgtaaacaca acattcgaga aacaaaaggg aaagatggag tctccaagat ttctaacatt 26580 ttagccagtg tttcttgaat aggcacagca tcccttaagt cataataata ataaaaaaga 26640 cgaattaatg tactcgtggc aagtctgcga acagtaacag agctcgtgtc ggaaattagc 26700 tgttgaaaaa tatgatcgat acaatcctta agtcccgggt tttgaaaatt gacagacaag 26760 aaaaacaaca tattatatac aggagaaaca acacaatcat cagattcctt agaaaagctt 26820 tcaattactg gaaaaaggaa tttcgaacac aaaatggggg ccgaattttc atcagcaaca 26880 gagcaagcat cttccacaag cttaaataaa agagctcgat cttcaagatc aaatgttttg 26940 cattggtaaa taccaagtaa aaattcaagg ttgaataccc aatattgatt gcaaggaaat 27000 ataagattgt aagtctcaaa aagacgtaaa agtttttttc gaattttcgg ctttaacact 27060 ggaagaacat ccttcaaaaa gaataccagc ttaacctgaa attgttgcag cagtggaatc 27120 aaggcttcga aatccaaaaa atccaaaaca cgatcatata tattagcaaa tgctgcagtc 27180 ttcgaaaatg cttccttcga tgtactagct ttcaaaggta gatattgtga acaatacatt 27240 aaaatattaa gaatccgatg ccaatccaaa aaattaaggc gatttaatat agaaggtgta 27300 cgtaaaaaaa gatacacagt accaaggatc tcaaaatcaa cattctcatt aaatcctaat 27360 ggaaactcag taaattcaat acttgaactt aaagttatag aagctattgc atcatttttc 27420 acttcttgca gcatgagaaa acgcattaaa cgcacagcgc cccgtacagc attaacattc 27480 gagcgattgt attgaagtat attaaatacg ttttcaaaag ccagatttga cacgggacta 27540 ctaataagat taaatataac agattgtgca agtttcgaat atgagtaggt gctgatgtat 27600 gtgctacaca aaataagaac agtatcatac agtgaagctt ttggaataac cgagtagcga 27660 atcatggaat caaaaaacat cagaacctca gtaaccacat cttctaagcg agcgtgatta 27720 catatttgta ccacggaatt aacaagctgt agcatttgag gttcaggcac taggaaccac 27780 tgaaatttta ctaagttggt agaaaactta aaaaggcttt taaaaaaaag caaatgtacg 27840 agctttgaat ctgcgtcttt gccttgcaat tcagttgctt gagattgcca ttgaagatac 27900 tggttaaacc atgcactcaa caaaggacca accctattct caataccgga gattttgtgc 27960 ccttcatccg ttaaaacact caaactctta agccgaagct gtaattcagc aatatcttga 28020 aaaggatctt tctcaatagt ttgaaaaaaa gtgtggcgct ctataatcga gagatgcttt 28080 tgtgtagaaa catatctcat cataagattg tatacaagct cccgaaaagc agcattatcg 28140 tttttggtgg agataaaatc ctgaatattt tgccatactt gaatgataga agtcgatgaa 28200 tatatatagt attttaagcc atggtaaata ctccttacaa tctgatgcct ttttttaaaa 28260 ggaaggttag catcaaaata tgatagaatg tctgtatctt tgatagcagg ctcactagaa 28320 agatccaaaa gtgatttatt gttcatctat gtggccttta tttttcaacg tcaataaatt 28380 aggaccttca gcagaataac cacataaagc aaatctgaac tcttaactta atggaatatt 28440 caagatcata aactatgagc atggaagttg atttcaagta ttagctacac tggtaggggt 28500 ggggaggaga gctgacaggc tgctatgaat taggggaagc attaccttat ctaagaggaa 28560 taggttgaaa cgacattaaa actaataaat agaaacttag tattcgacat tcaaaattca 28620 aaaaatatat gaagttattt aaccgtaaaa accaattgct aagtagctag gtcgcgcaaa 28680 catatacata acttgaaggg tctattaaat atatacaaaa gttgggattt aatagttaat 28740 gaaatactat ggataaaatc agagtttcgg ttgtcgggga ttgtatggaa gtatcaaaaa 28800 ttaaaaaaag ggaattgaaa tgattcaaga attagcaaaa acatctggtc ggcttgactt 28860 gatagaaaaa ttccgaccaa aataagccgc aagtttgaag ggttacaaaa tcggttatga 28920 atttttataa aataaaggaa aaaagacttg ccaagaagcg agtctcacaa tggtcaatgg 28980 gcattattgg caaatgaaga attaaaaaat taagtaggtt tcggacattg tcattcaatg 29040 ctataaatga aacatcgcta gttcttacag atcctcataa gaccaaattc ttgctcgtaa 29100 gtcaccacta ccagtagcaa agcaatggcc attcgggcta acagcaaccg atattactga 29160 gttattgtgt ccctggagag ttaactgaga atgaggagaa tcgggggacc aaaattggat 29220 ggttcggtct ttcgagccgc taataatcca ttttccatcc ggagagacag tgacacttag 29280 aataaaatct ttatgtccag taaaagtttg cttgcaaata ccgccttcct tatacatgct 29340 gggtgcaacg ttggagacgc attgcaactc ccataactta attgtgttat ccaaacttcc 29400 actaaccagg tattttccgt caggagagaa ggcaacgctg taaacactct cttcatgacc 29460 atgaagctgc tctactaaag ttccggacga tgtccaaatc ctaattacct tatctaaaga 29520 acctgcagca ataaattgac cgtcgggaga aaacattact gtagtaacac catcatcggt 29580 atgcaaaatt agtttttgct cgccagcttc aacatcccaa agacaaacag ttctatctcc 29640 actaccagaa accaatgttt ttccatcttt gctaaaatca agggaataaa tttcttgctc 29700 atgcccagtc agtagacgat aaacacgttt ttgagcgatg tcccatattc tgatttgttg 29760 atcttcgaca ccagtagcaa ggtatttacc atcaggacta aatgctacac tgcgaacata 29820 taaatcacct tcacgcttcg aagattcctc ctgcagaagc gtaattaatt taccggtctc 29880 cacattaaaa accatagctg ctctgttaca acccgtagcc aaaaattttc catcggcact 29940 aaaccttaca taacaaataa cgcttgtgtg ttccagtgta tgaagtagtt gaacagagat 30000 cgggggttct ttgttaggta cattgctagt gacagtccaa tctttctcct ctctattagg 30060 cacattggat gtcggaataa tttcagcagg ataaggagga ttacctgaga cttttccgtt 30120 tacaaccaaa ggagcagcga taggtgtgac ggaagaatta gctgagtcag atggaggtgg 30180 aggatgtccg agcggtaaat tggaaggaaa tgctgtgaat ggtaagtaag aaaatccaaa 30240 ttaaaacgag gaagcaaaat agtttcggca atagtatttt gttttacaaa aaatgaacaa 30300 aagccgcaag gaattcaaac gaattaatga cagcattaaa aaattgtctg ggaacatacg 30360 gtgtacaaca taccagatgc aaacaataaa gtgaaagaca aaaagtatct ataaacttga 30420 tcaagtcaaa aaacaaatgc tgttgccaaa agctacaatg caagcttgaa cttacttcgc 30480 atagcagatc cagccatggt tgcacccaca gcagggcgta catgaggact ggaataatat 30540 tgtgaaccaa gatctacgtt cgaggtctga ataggagcta aaacagtacc atctgaatca 30600 atggcaggtg atcgaagatt tttaggagtt cctccagaag aaccgttatt aagtatcaaa 30660 ggtttcgagg agttgtccga gttaaaaggg cccgcatttc catattttcc aaaagaaacg 30720 ctattgcgcc cgtgtttagt tttcgaagac tgtgggacga cgccagaagc aatttctttg 30780 cgtctagctt ccagttgagc ttttaaggag gtgatttctt cttcgtaact agagagagtt 30840 agtaacaaga aagatagctt tcgagaaaat ataatataaa attgagaata aatgttcaca 30900 tagcagaagg catgctggtg ctgacaaaag tgtgaaaagg acagagaatc ttcgaacagt 30960 gataaacatc caaatactga gtaaaaaacg aaataccctt catcggagta aaaatatgaa 31020 aagattactt aatagaattt actcccatca aaggagccac cattatttag catctttaaa 31080 gatttatcgt caacgaccgt aaattgtata aatatttaga gaggaatcgc ttttgtaaga 31140 ctctacaaca ctcacaataa ttgcataacc ttgtactaat ataacaaacc ttctcgccaa 31200 gcgtgtatta ggaaaattga cataccgatc cttcacttta gactgctgca tctccaaatc 31260 cataacggtt tgtttcatga gcgccatttc attaatttgt gcagatatca ttgctaattt 31320 aagaagtgtt agatttgtac cgcaaatttg tcagcaaatt cttgtataag atacctttat 31380 attcaaaatc atccttttga gcttcaacgg ttttagtttt ttgacaaata tcttcaaatt 31440 cctttttaac cgcttctaaa agctcattta cacgtgatga tacattggac gtcgccataa 31500 attgaaactt gaagatggta aaagtgaatt ggcggacagt aatcatgaat gatgttgttt 31560 gagaaataac gagaaataac attcgttaat ttcggtaaaa ccttctcggc ttcgaagcta 31620 aagtaagcaa actatgttga gattaacatg tcaggaaaga caatttcact tatgcttagc 31680 gagacaatat tgttgaatta gtaatttggc tgttcattca acttgccgca gttggaaaat 31740 gtaaaatcat taatttgtga tgaaacctcg taaaacatat tttttaacgt taatcgattg 31800 aaaccctttt tgaattagtt cgtgaaatat cttaactcta aaaccttgaa aatctttaga 31860 tagaagatcc tttttttttt tttttgggaa gaatatgaag cgttttgata caattggtaa 31920 taaaacatta tttggtattg gtttttattg gaagtttagt tttacaaaag tgtagatgtc 31980 ataatcctaa tatgaattct 32000 //