ID   SPAC5H10   standard; DNA; FUN; 24845 BP.
XX
AC   Z49811;
XX
SV   Z49811.1
XX
DT   05-JUN-1995 (Rel. 44, Created)
DT   12-DEC-1999 (Rel. 62, Last updated, Version 7)
XX
DE   S.pombe chromosome I cosmid c5H10.
XX
KW   5S rRNA; alcohol dehydrogenase; methyl transferase;
KW   modulator of drug activity B homologue; NADHPH dehydrogenase;
KW   PANB homologue; PANC homologue; pantoate beta-alanine ligase;
KW   pantothenate biosynthesis; rad8; SNF2 helicase.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-24845
RA   Connor R., Churcher C.M.;
RT   ;
RL   Unpublished.
XX
RN   [2]
RP   1-24845
RA   Barrell B.G., Rajandream M.A., Walsh S.V.;
RT   ;
RL   Submitted (23-MAY-1995) to the EMBL/GenBank/DDBJ databases.
RL   Annotation update submitted 18-JUL-1995 Schizosaccharomyces pombe
RL   chromosome I sequencing project, Sanger Centre, Hinxton Hall, Hinxton,
RL   Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk
XX
DR   GOA; P36607; P36607.
DR   GOA; Q09669; Q09669.
DR   GOA; Q09670; Q09670.
DR   GOA; Q09671; Q09671.
DR   GOA; Q09672; Q09672.
DR   GOA; Q09673; Q09673.
DR   GOA; Q09674; Q09674.
DR   GOA; Q09676; Q09676.
DR   GOA; Q09677; Q09677.
DR   GOA; Q09679; Q09679.
DR   GOA; Q09680; Q09680.
DR   GOA; Q09681; Q09681.
DR   SWISS-PROT; P36607; RAD8_SCHPO.
DR   SWISS-PROT; Q09669; ADHF_SCHPO.
DR   SWISS-PROT; Q09670; OYEA_SCHPO.
DR   SWISS-PROT; Q09671; OYEB_SCHPO.
DR   SWISS-PROT; Q09672; PANB_SCHPO.
DR   SWISS-PROT; Q09673; PANC_SCHPO.
DR   SWISS-PROT; Q09674; YA01_SCHPO.
DR   SWISS-PROT; Q09675; YA02_SCHPO.
DR   SWISS-PROT; Q09676; YA03_SCHPO.
DR   SWISS-PROT; Q09677; YA05_SCHPO.
DR   SWISS-PROT; Q09678; YA07_SCHPO.
DR   SWISS-PROT; Q09679; YA0B_SCHPO.
DR   SWISS-PROT; Q09680; YA0C_SCHPO.
DR   SWISS-PROT; Q09681; YA0D_SCHPO.
XX
CC   Notes:
CC   Annotation update 18-JUL-1995
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPAC5H10.01c.
CC   SP (S. pombe), A (chromosome 1), c5H10 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c5H10 is overlapped at the 5' end by c11D3 and at
CC   the 3' end by c13G6.
CC   NOTE: There are 14 predicted CDS in this sequence and one
CC   5S rRNA gene.  We do not predict any splicing in the 14 CDS.
CC   c5H10 is located towards the left telomere.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..24845
FT                   /chromosome="I"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c5H10"
FT                   /map="1L"
FT   misc_feature    1..6
FT                   /note="nominal overlap with cosmid SPAC11D3, EM:Z68166
FT                   S.pombe chromosome 1"
FT   CDS             533..1438
FT                   /db_xref="GOA:Q09674"
FT                   /db_xref="SWISS-PROT:Q09674"
FT                   /note="SPAC5H10.01, len:301, SIMILARITY:Bacillus subtilis.,
FT                   YCSI_BACSU, hypothetical 28.1 kd protein, (257 aa), fasta
FT                   scores: opt: 723, E():0, (45.1% identity in 253 aa)"
FT                   /gene="SPAC5H10.01"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAA89951.1"
FT                   /translation="MTTTSIDPPVYATVDVIREPKAYDGMPKKDECRLPSYSERAITKP
FT                   VEARKLIRNRLMTKSTTGWCEGYIQANLLVLPAKYRDDFVNLCVRNPVPCPLLGETEIG
FT                   KPTEFKPEALAKQSNVATDIPFYCEYINGKFSRELENISKEWTEDYVGFLIGCSFSFEA
FT                   ALVAENFIPRHLPTGDAPPMFITNIPLCASGVFTGTFVVSMRPYPEKDLERIRKITSAY
FT                   TNCHGEPVAWGWDGAKKIGVKDCGKPDFGVPVEFKEGEIPIFWGCGVTPQNVVMMSKLP
FT                   EPVYSHKPGYMYLTDLTHNC"
FT   CDS             complement(1772..2494)
FT                   /db_xref="SWISS-PROT:Q09675"
FT                   /note="SPAC5H10.02c, len:240,
FT                   SIMILARITY:Schizosaccharomyces pombe, O74914, conserved
FT                   hypothetical protein., (244 aa), fasta scores: opt: 986,
FT                   E():0, (60.7% identity in 234 aa)"
FT                   /gene="SPAC5H10.02c"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAA89952.1"
FT                   /translation="MSIAKGKNALLVASSYYGPFYPDGKNTGVHFSELLIPYNVFKKAG
FT                   FNVQFVSENGSYKFDDHSIEESKLGDFERKVFNDKNDDFWTNLNNMKKASDIVGKDYQL
FT                   LFVAGGHAAMFDLPKATNLQAVAREVFTNGGVLSAVCHGPVLLANVKNPQSVEGKTVVY
FT                   HKHVTAFNKAGEEKMGVMDELKKRGMKSLNEIFAEAGATFIDPPNPNVNFTQIDGKIVT
FT                   GVNPQSAKSTAEAAVSAL"
FT   rRNA            3217..3335
FT                   /note="5S rRNA gene"
FT                   /gene="5SrRNA"
FT                   /product="5SrRNA"
FT   CDS             5472..6131
FT                   /db_xref="GOA:Q09676"
FT                   /db_xref="SWISS-PROT:Q09676"
FT                   /note="SPAC5H10.03, len:219, SIMILARITY:Schizosaccharomyces
FT                   pombe, CAB58725, hypothetical 25.2 kd protein., (216 aa),
FT                   fasta scores: opt: 479, E():4.5e-25, (35.6% identity in 205
FT                   aa)"
FT                   /gene="SPAC5H10.03"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAA89953.1"
FT                   /translation="MTNNLKKTVYLIRHGQAQHNVGPDEDHNIRDPVLTSEGIEQCEAL
FT                   AKELESKQIPIDGIVCSPMRRTLQTMEIALKKYLAEGGPDKVPVYISPFFQEVGHLPCD
FT                   IGLELDKLNKLYPKYNFQSCQDGIYPEKRDIYASDVTISAIRSKEALEYLAALPQQQIA
FT                   VITHSAFIRFLLKKMVKAADIDFLPPQLSFKNCEFRIYDLVQTTTGELKLVESSSA"
FT   misc_feature    5502..5531
FT                   /note="PS00175 Phosphoglycerate mutase family
FT                   phosphohistidine signature"
FT   CDS             6946..8094
FT                   /db_xref="GOA:Q09670"
FT                   /db_xref="SWISS-PROT:Q09670"
FT                   /note="SPAC5H10.04, len:382, SIMILARITY:Schizosaccharomyces
FT                   pombe, OYEB_SCHPO, putative nadph dehydrogenase c5h10.10,
FT                   (392 aa), fasta scores: opt: 1542, E():0, (57.5% identity
FT                   in 381 aa)"
FT                   /gene="SPAC5H10.04"
FT                   /product="putative NADPH dehydrogenase"
FT                   /protein_id="CAA89954.1"
FT                   /translation="MNDRGELFKPIKVGNMLLQHRIVHAPMTRLRATDYGKITGLMVEY
FT                   YSQRSMIPGTLLIADATFVGEKSGGFPNNPRCFTKEQAESWIPLVEAVHKNKSFLFIQF
FT                   WPLPGDLKDEYRNDLEKMQKITYSDCPQDPGGLPAGIHSFDAVQGVEVYKKKYMSKRDI
FT                   QEHIQDFVNAADLAVNIAKADGVEIHQVNGFLLDRFVLGGFGDQCDPEYRGSIENRCRF
FT                   PLEVLEAVTRKIGQERVGYRISPFSGWMQKIDFMEVNIYLMSEIAKRFPKLAYIHAIEP
FT                   RKYWSGHKLVSSEQNTSFLQKYWKGPFITAGGYDPETAVQAANERGVLVAFGRNFIANP
FT                   DLVFRIKHHIPLNKWDRSSFYLPKTEKGYTDYPFSKEFLQSK"
FT   misc_feature    6961..8004
FT                   /note="Match to oxidored_FMN ,  Score 649.99"
FT   CDS             complement(8366..8956)
FT                   /db_xref="GOA:Q09677"
FT                   /db_xref="SWISS-PROT:Q09677"
FT                   /note="SPAC5H10.05c, len:196, SIMILARITY:Escherichia coli.,
FT                   MDAB_ECOLI, modulator of drug activity b., (193 aa), fasta
FT                   scores: opt: 778, E():0, (56.8% identity in 190 aa)"
FT                   /gene="SPAC5H10.05c"
FT                   /product="modulator of drug activity homolog"
FT                   /protein_id="CAA89955.1"
FT                   /translation="MKILLINGAQEFAHSQGKFNKTLHNVAKDTLIQLGHTVQETVVDE
FT                   GYDENTEVEKILWANVIIYQWPGWWMGTPWKLKRYMDEVFTAGYGQLYANDGRSSKNPT
FT                   QNYGKGGLLHEHRYMISCTWNAPAAAFEEVGNFFDGRGVDGTLLTFHKANQFLGMKPLP
FT                   TFMVNDVIKNPKVDIAVCAYKDHLNDVFGSANA"
FT   CDS             complement(10107..11375)
FT                   /db_xref="GOA:Q09669"
FT                   /db_xref="SWISS-PROT:Q09669"
FT                   /note="SPAC5H10.06c, len:422, SIMILARITY:Saccharomyces
FT                   cerevisiae, ADH4_YEAST, alcohol dehydrogenase iv, (465 aa),
FT                   fasta scores: opt: 1511, E():0, (55.7% identity in 415 aa)"
FT                   /gene="SPAC5H10.06c"
FT                   /product="iron containing alcohol dehydrogenase"
FT                   /protein_id="CAA89956.1"
FT                   /translation="MSILRSPFRLIRSPARFFPSLFHSSCNQSFTNGLKHQSTSSKAMP
FT                   VSAFYIPSFNLFGKGCLAEAAKQIKMSGFKNTLIVTDPGIIKVGLYDKVKALLEEQSIT
FT                   VHLYDGVQPNPTVGNVNQGLEIVKKENCDSMVSIGGGSAHDCAKGIALLATNGGKIADY
FT                   EGVDKSSKPQLPLIAINTTAGTASEMTRFAIITEETRHIKMAIIDKHTMPILSVNDPET
FT                   MYGLPPSLTAATGMDALTHAVEAYVSTAANPITDACAVKCIELVNKYLKRAVDNGKDEE
FT                   ARDNMAYAEFLGGMAFNNASLGYVHAMAHQLGGFYGIPHGVCNAVLLAHVQKFNSRDPR
FT                   ANARLGDIAFHLGCEEHTAEAALDRISQLVLEVKIRPHLVDLGVKEKDFDVLVDHAMKD
FT                   ACGATNPIQPTHDEVKAIFKSAM"
FT   misc_feature    complement(10134..11222)
FT                   /note="Pfam match to entry Fe-ADH PF00465, Iron-containing
FT                   alcohol dehydrogenases"
FT   misc_feature    complement(10413..10460)
FT                   /note="PS00060 Iron-containing alcohol dehydrogenases
FT                   signature 2"
FT   misc_feature    complement(10644..10739)
FT                   /note="PS00913 Iron-containing alcohol dehydrogenases
FT                   signature 1"
FT   CDS             12762..13031
FT                   /db_xref="SWISS-PROT:Q09678"
FT                   /note="SPAC5H10.07, len:89"
FT                   /note="possible est"
FT                   /gene="SPAC5H10.07"
FT                   /product="very hypothetical protein"
FT                   /protein_id="CAA89957.1"
FT                   /translation="MTVLTSYKLYCGPDFPAPLEKKEKREKGKIRNISFLIVLTKGPIW
FT                   KVSSMESTSYNGCIENLDCKFRKSFIEEIIAYEGFGKYIEVINF"
FT   CDS             complement(13653..14504)
FT                   /db_xref="GOA:Q09673"
FT                   /db_xref="SWISS-PROT:Q09673"
FT                   /note="SPAC5H10.08c, putative pantoate--beta-alanine ligase
FT                   len: 283, similar to SW:PANC_ECOLI P31663
FT                   pantoate--beta-alanine ligase, (59.6% identity in 277 aa
FT                   overlap)"
FT                   /note="SPAC5H10.08c, len:283, SIMILARITY:Escherichia coli.,
FT                   PANC_ECOLI, pantoate--beta-alanine ligase, (283 aa), fasta
FT                   scores: opt: 1105, E():0, (59.6% identity in 277 aa)"
FT                   /gene="SPAC5H10.08c"
FT                   /product="putative pantoate--beta-alanine ligase"
FT                   /protein_id="CAA89958.1"
FT                   /translation="MQVLKEKLLIHQQVDNWRKDGNRIAFVPTMGNLHEGHFSLVREAK
FT                   RHAEKVVVSIFVNPMQFNNPQDLLLYPRTMDQDCSQLQNLGVDLVYAPTVEELYPEGSQ
FT                   DITFVDVPKLSTMLEGASRPGHFRGVTTVVSKLFHIVNPDVACFGEKDFQQVAIIKKMV
FT                   RDLNFFIEIIQVPIVRADDGLALSSRNGYLTSEERKIAPNLYKILKKLAQELSNGNGDL
FT                   EKLIAETNTELSRCRFIPDQLEICDSTTLEPFTAGTKNVVILAAAWLGKARLIDNIQTT
FT                   IN"
FT   CDS             complement(14536..15339)
FT                   /db_xref="GOA:Q09672"
FT                   /db_xref="SWISS-PROT:Q09672"
FT                   /note="SPAC5H10.09c, putative 3-methyl-2-oxobutanoate
FT                   hydroxymethyltransferase, len: 267, similar to
FT                   SW:PANB_ECOLI, P31057, 3-methyl-2-oxobutanoate
FT                   hydroxymethyltransferase (67.9% identity in 265 aa
FT                   overlap)"
FT                   /note="SPAC5H10.09c, len:267, SIMILARITY:Escherichia coli.,
FT                   PANB_ECOLI, 3-methyl-2-oxobutanoate
FT                   hydroxymethyltransferase, (264 aa), fasta scores: opt:
FT                   1180, E():0, (67.9% identity in 265 aa)"
FT                   /gene="SPAC5H10.09c"
FT                   /product="3-methyl-2-oxobutanoate hydroxymethyltransferase"
FT                   /protein_id="CAA89959.1"
FT                   /translation="MSLKQITISTLRQWKLANKKFACITAYDASFSRLFAEQGMPVMLV
FT                   GDSLGMTAQGHSTTLPVSVEDIAYHTKSVRRGAPNRLLMADLPFMSYSTWEDACKNAAT
FT                   VMRAGANIVKIEGGGNWIFEIVQRLTERSVPVAGHLGLTPQSVNIFGGYKIQGREQSAA
FT                   ARLIENAQQLEKFGAQLLVLECIPESLAEQITKTISIPTIGIGAGKHTDGQILVMHDAL
FT                   GITGGRPPKFAKNFLSGAGDIRTAIQRYIYEVEQGLYPAEEHSFQ"
FT   CDS             16519..17697
FT                   /db_xref="GOA:Q09671"
FT                   /db_xref="SWISS-PROT:Q09671"
FT                   /note="SPAC5H10.10, len:392, SIMILARITY:Schizosaccharomyces
FT                   pombe, OYEA_SCHPO, putative nadph dehydrogenase c5h10.04,
FT                   (382 aa), fasta scores: opt: 1542, E():0, (57.5% identity
FT                   in 381 aa)"
FT                   /gene="SPAC5H10.10"
FT                   /product="putative NADPH dehydrogenase"
FT                   /protein_id="CAA89960.1"
FT                   /translation="MAVQKLYESQSKLFQPIKVGNMQLQHRMVHAPATRLRCLDNGLVM
FT                   TDLVKEYYKQRSSIPGTLLITESLFSGAKSGGFSNIPCLYNDEHVEAWKPIVQAIHDND
FT                   CFVFIQFWNLPGELKVDYLEDQERLEKVTQGECPMDPTGLPAALGSAYSICGEELYVDK
FT                   FMTKQDIQEHITTYTEAAKRAVFGCGADGVEVHQVNGFLLDKFVLNGYGDKCDPEYCGS
FT                   LENRARFCLELLESVVNAIGQERVGYRISPFSDIWKDKDSFEAHVFMIKKIKERFPNLA
FT                   YLHAIEPRQYWNGHVHITQEKNTLIYKNLWGDPFITAGGHDRDSAIQMAEQENTLVAFG
FT                   RYFLSNPDLPFRLKYNLPLNKWDRATFYTKMSPKGYIDYPFSKEFLDTKKVE"
FT   misc_feature    16552..17598
FT                   /note="Match to oxidored_FMN ,  Score 648.36"
FT   CDS             18287..19276
FT                   /db_xref="GOA:Q09679"
FT                   /db_xref="SWISS-PROT:Q09679"
FT                   /note="SPAC5H10.11, len:329, SIMILARITY:Schizosaccharomyces
FT                   pombe, YDB6_SCHPO, hypothetical 38.1 kd protein c22e12.06c
FT                   in chromosome i., (332 aa), fasta scores: opt: 1068, E():0,
FT                   (47.9% identity in 317 aa)"
FT                   /gene="SPAC5H10.11"
FT                   /product="putative galactosyltransferase"
FT                   /protein_id="CAA89961.1"
FT                   /translation="MLSFFTKNTLTKRKLIMLALAIVFTFFAFGLYFIPHDEISVFDFK
FT                   LPALQYETTVTSLDNFLIGGSTTLYTATVNHEDLNEPKSHEIVMLLASDGNVGSFESNL
FT                   LDDCFKNRIEYAKLQNYNFEFVNVSSLVVPPVWGKMPAILQTMRKYPSAKWIWWLDQDA
FT                   LIMNKNLSLQELFLSPAMLQKSLLREQPIINSFGEDNFRITPAAYSKEMIEQIQFLISQ
FT                   DHNGLNAGSFLVRNSRSIALLMDLLTDPSLADAGVVRHEQDLIGYFIQKHSQVASMVGI
FT                   LPQRFINAFHEGPPTMQWQEGDLALHFAGCWVENKCAELWTKYKDKII"
FT   CDS             complement(19979..21094)
FT                   /db_xref="GOA:Q09680"
FT                   /db_xref="SWISS-PROT:Q09680"
FT                   /note="SPAC5H10.12c, len:371,
FT                   SIMILARITY:Schizosaccharomyces pombe, O43062, hypothetical
FT                   44.1 kd protein., (376 aa), fasta scores: opt: 1288, E():0,
FT                   (49.1% identity in 373 aa)"
FT                   /gene="SPAC5H10.12c"
FT                   /product="putative galactosyltransferase"
FT                   /protein_id="CAA89962.1"
FT                   /translation="MSRISLSNFLSLPRYKFLLFSVVLIIVMTTLVFNGHDYKQTLNDR
FT                   LTSLKNNFVEENDNAVLKEEPGKYTYMSLFTMPSTEEDYYFNATRVLIHRLKYHPTTKS
FT                   KYPIHILALRGVDEWKIERFRKDGASVIVIDPIASSDIVYDTSSFSQEISARYEQMFSK
FT                   LRIFEQIQFDKICVIDSDILIMKNIDDIFDTPYMYQQINTLNYTRLPSYTKPDDDTVYH
FT                   FNEDFKEYGASRSEFYPYLLAAVSDRGEHHSIPPEDTPYFNAGLMLIRPSELHFNRILK
FT                   IGRFPYMYENAKMMEQSLLNLAFSLDGWFPWTRLDPYYNGVWPSIDERPLLKTAHGKFW
FT                   NIGSSEFAPVYLADWYAAYGEMLSFHKYETH"
FT   CDS             complement(22369..23409)
FT                   /db_xref="GOA:Q09681"
FT                   /db_xref="SWISS-PROT:Q09681"
FT                   /note="SPAC5H10.13c, len:346,
FT                   SIMILARITY:Schizosaccharomyces pombe, YA0B_SCHPO, putative
FT                   galactosyltransferase, (329 aa), fasta scores: opt: 1016,
FT                   E():0, (47.3% identity in 332 aa)"
FT                   /gene="SPAC5H10.13c"
FT                   /product="putative galactosyltransferase"
FT                   /protein_id="CAA89963.1"
FT                   /translation="MALMLSRIPRRFFFLFLTVGLIAGAFLYSLIYFVDVDLVSKVNQL
FT                   YDQQIAPMLSDAIGTPSVNHSFELAPLDSHLVATSTTFHEASYESEPQQNPASQNIVLL
FT                   LVSDGHTSYNNGANTFEEAIQNRVDYSTKQNYNFEYVNVTGLPIPAVWSKMPAVLQTMK
FT                   KYPKAEWIWLLDQDAIITNTHLSLQDSFLKPENLQKTLITNTILTKRPINANGDLRYTP
FT                   SNYSLKDIENLMVIISQDHNGLNAGSILFRNSPATALFLDIWTDPVVAECAKANNEQDM
FT                   LGYLISKHSQLASLVGLIPQRKINAFHEGPENMEWQKGDLVIHFAGCWVENRCDELWQK
FT                   FYALID"
FT   CDS             complement(24531..24845)
FT                   /codon_start=1
FT                   /db_xref="GOA:P36607"
FT                   /db_xref="SWISS-PROT:P36607"
FT                   /note="SPAC5H10.14c, len:104"
FT                   /partial
FT                   /gene="rad8"
FT                   /gene="SPAC5H10.14c"
FT                   /gene="SPAC13G6.01c"
FT                   /product="dna repair protein rad8, helicase"
FT                   /protein_id="CAA89964.1"
FT                   /translation="DPDVNVLIISLKAGGVGLNLTCANHVFIMDPWWSWSVEAQAIDRI
FT                   HRLGQEKPVFVTRYIVRDTVEERMLKIQERKNFITGTLGMSEGKQQVQSIEDIKMLFEY
FT                   "
FT   misc_feature    complement(24699..24842)
FT                   /note="Match to helicase_C ,  Score 32.43"
FT   misc_feature    24721..24845
FT                   /note="nominal overlap with cosmid SPAC13G6, EM:Z54308
FT                   S.pombe chromosome 1"
XX
SQ   Sequence 24845 BP; 8060 A; 4516 C; 4440 G; 7829 T; 0 other;
     cagatccata tctaatttcc taatagttac aaaagagggg gttttttatc attgataaac        60
     gacgatgtag gttttcctat agtagttgta gtactagttc gtctagcaat cgtgtaattt       120
     attgatagac gctggattta ctggacgatg agcagagctc ctccagctta ttgactatca       180
     tgcttatatt ttctaatagc gaataaatgc gattgtatta aagaacgtgt tattatatca       240
     tcgagctccc aagcaacgat taatttcacg aatacactat cagttagctt aataggagga       300
     gctcccaatc aagtttgcaa aatgtaagct gaaacttcgt gcagtcaatt taggcataaa       360
     atcatgatat gtttaataga taaaagtatt tgcacacaaa tatatatata gttacgaaaa       420
     ggattaggct aaaaaattaa ttagaaacct tcttttggga aatacattac tataagaaaa       480
     tctaccacta ataatagaac tgtggatcaa ttgatttgaa attacaataa taatgactac       540
     tactagtatc gatccaccag tgtatgccac cgtcgatgta attcgcgaac cgaaagcata       600
     tgatggtatg cctaagaagg acgagtgtcg tctcccttcc tattcagagc gagcaattac       660
     gaagcccgta gaagctcgta aattaattcg aaacagatta atgaccaagt ccacgactgg       720
     atggtgcgag ggatatattc aagcaaacct tttggtcttg cctgccaaat atagagatga       780
     tttcgtaaat ttgtgcgttc gcaatcctgt tccttgtcct ttgttgggag aaacggaaat       840
     tggcaagcct actgaattca aaccagaagc tttggctaaa caaagcaacg tcgcaacaga       900
     tattcctttc tattgtgaat acatcaatgg caaattttca agggaattag aaaatatttc       960
     caaagagtgg actgaagact acgtcggctt cttgattgga tgctctttct cttttgaagc      1020
     tgcactagta gctgagaatt ttatcccaag gcatttacca actggtgatg cacctccaat      1080
     gtttattaca aatatccctc tttgcgcatc tggcgttttt actggtactt ttgtagtctc      1140
     catgcgtcca taccctgaaa aggaccttga aagaatcaga aaaattactt ctgcttatac      1200
     gaactgccat ggagaacctg ttgcatgggg ttgggatggt gctaagaaaa ttggagtcaa      1260
     agactgtgga aaacctgact ttggcgtgcc tgtcgaattc aaagaaggtg aaatccctat      1320
     tttctggggc tgtggtgtta ctccacaaaa cgtagtaatg atgagtaaac tacctgagcc      1380
     cgtttactct cataaacctg gctacatgta tttgactgat ttaacccata attgttaata      1440
     gaatatacca gctctttctt tttgtcattt acgagcgcta actgttacat taagcgatca      1500
     tttgcagcag cagcaaatta tatagttacc aatgaatatt tatctaccat aattgagacg      1560
     gcattcaatc tcaacaatac ttggtcatga ataatcgcaa aagttgtagt actaaattta      1620
     taatatttat aaaacagtat cgcaaattag caatgcttca cttgagcata agcatcactt      1680
     ttaatgaaca gcagatctgc gaaaaaatta tcttccaatg tttttctttt tatttatttc      1740
     gtataactca taacaacaaa caacataatt tttataatgc gctaacggcg gcttcagcag      1800
     tcgattttgc gctctgcgga tttacccctg ttacaatttt tccatcgatc tgagtaaagt      1860
     tgacattggg gtttggtgga tcaatgaaag ttgcccctgc ttcagcaaat atttcattta      1920
     aggatttcat ccctcgtttt ttcaattcat ccataacacc cattttttcc tctccagcct      1980
     tattaaaagc tgtaacatgc ttatgataca cgactgtttt gccttcaact gattgtggat      2040
     tctttacatt ggcaagcaaa acagggccat gacagactgc cgataaaaca ccaccatttg      2100
     taaacacttc tcttgctacc gcctgtaaat tcgtggcttt gggtaagtca aacatcgcag      2160
     catgcccacc tgccacaaat aaaagctgat agtcttttcc aactatgtcc gaagcctttt      2220
     tcatattgtt aagattagtc caaaaatcgt cgtttttatc attaaatact tttctttcaa      2280
     agtcccctaa ttttgactcc tcaatggaat gatcgtcaaa tttgtaagag ccattttctg      2340
     aaacgaattg cacgttaaaa cctgcttttt tgaaaacatt gtaagggatt aaaagctctg      2400
     aaaaatggac tccagtgttt ttaccatctg gataaaatgg gccataataa ctgctggcaa      2460
     caagcaatgc attttttcct tttgcaatag acattaggga aagatagtct gtagaaatag      2520
     atgaaagcca agcaaacaaa caaataatag aataaaaatg atcgatatta ttgatataaa      2580
     atcaattcaa cgtttcgtag atgtaaagat atatatatat atatacacta ttcaatcttt      2640
     aaatcaacac aaaaaatcat gctcctacca tattacaaaa tatgaagtca tgaaattcga      2700
     agctgttcta gggtcgattg ttgttgcatt caatagatgt cattctatat catatagcaa      2760
     tttctactat gtaaagattc ctgctgtacg gaagaacctt aagtactttt ctagatgaca      2820
     acaaggacta atgaggtttt tacacacttg tgtaacaaaa aacgaggctt taaatatatt      2880
     gtataaaaaa ctactttcta atcggttaaa accatgacta gacccttgat agactatgta      2940
     acgtcactag gaggctaata aatttgacag tgttttgttt gcgtttgtag ctagttcatt      3000
     aactctatta taaggatttc gggtaaaaca ttcctttact gaaaatgact tagcaaaaga      3060
     tatgtagttt taaatatcca taattgaaat caattcatga ctattgtata ccatttgcct      3120
     gatggtgttc aatgatccaa cacttaaaac aggctctgct ggtagacaat ataaaataca      3180
     ttttaagtat ttatagagct atttactgat ccaaatgtct acggccatac ctaggcgaaa      3240
     acaccagttc ccgtccgatc actgcagtta agcgtctgag ggcctcgtta gtactatggt      3300
     tggagacaac atgggaatcc ggggtgctgt aggctccttc ttttttgatt ttatatcatt      3360
     tttttgtgaa ctggttgttt aattagcaaa acttcaatag aagcattgtt ctaaagttgt      3420
     tgaagcagta aattattacg caaacctaat gaataaagct aggaaaggtg accccgtctt      3480
     tgaggtttac atcaggttaa cagacagacg agatttctcg ggttttcgtt tctacgttgc      3540
     tgagaataca gaaaaagatc tagtagtgtc taatagtaaa ttacaaaaag gttcaataca      3600
     gataagaaat ttgtttcctt gcaaacattg gattatcaat ataattagaa ggaattgatg      3660
     aacgttttaa ctgcgttttg ctgaagctca tttaaccttt tttttcatga aacggccaag      3720
     cttgttagta tgctctcacg cacagaacgc atttacaagt attttaatca tcctgcattt      3780
     aacggcatgt caaaacagaa aatgctaaag aacgatacct tctcgttcgg taaataatgt      3840
     ttctgtaaag aagtaataat agaagtgcgt aagtgtttac ctaatttacc gactttgacc      3900
     atgtgtacta cctactacta gtattgcgct atcagatcta aactagagct ccactcggct      3960
     tgtccatgaa cccggcaaaa tttacattat tttttagccg ttgatgttta taatcctttt      4020
     ctagtaaatg gctaactatc aatttgatat ttttattaga tattctttac atcattttgc      4080
     actagcagcc cagaggatat cgataataaa gatgtattac tatactatat tatgcttatg      4140
     cgatatcgca atactgaggc tttgagtttt ggatgaaact ggcataatgc aggtgattgg      4200
     tatatatatt gatattatat aaaatatgta ccaaatttac atatgcatat attgatgtgt      4260
     acgttgtagc aaaatgcgcc gaaggtttca tctccatttg ctatattcca tctaaacttg      4320
     cctagtattt tacttggctt taagagtgaa atttgacttt ttgagttgtt ttgtttttgg      4380
     cttttttttc attgcctgcg gaaaggacac gttttactat tctaattaag acacaacttt      4440
     ttaaatgtcc atttgaatta agcgttaaga ttatttattt aaaattcaaa tatgttgatt      4500
     ttcccaggtt catacttcta catattttta tggcagcgtc tatagaaaaa aatgcattaa      4560
     ctctactaac caatatcact agcgtgagca tgcacttcta taacggaatt cacccttcat      4620
     ctcgttattt tgacatcggc aaacttcaga ctatcgatac atttattctc tatcatgccg      4680
     gatattgtcg ttagtaaaag ataatacgga aaagaactaa ttcttattgg ttttttttat      4740
     gtacattcag ctgatattta tctttactcc attgcgcttt gtcaaagtgc ctgcttgaag      4800
     catagaacag caaaggcaaa cgattgagag tatatagtta attgctttaa gtacattata      4860
     ttcgttcggg tctttcgcaa aaatttttca ttgtctatgt agcaaacata tgagtgcaat      4920
     tcctaaattt ttaacatttt ttttatgttg agtatgaatt aatttacgac cgaccaactc      4980
     gtgcgacgcg ttgtttgatg agtgtacgga aagtgatttt taattaaatt atctaatagt      5040
     ccgttattcg tggcttatct tacttaaaaa gagaatatta tattctaata aaacgaatat      5100
     aagcacgttt tcgatatgac tatcagttgc catatcaacg atacaaaaaa aaataaaaaa      5160
     aataaatgcc gcgatttttt ttcaaagcaa ttttccatga ctgagagaac actgggataa      5220
     aatataaata tatatttttt taatctgtct gttgcatgtt tgcttttgtt ttcgtttttg      5280
     tctttgtttt ttcctttttc atgctacttg cacgttggtc ttttcttccg attatcgacc      5340
     gaccaacgaa ttggctgaat tgttatcggt tcggaaacga gatttttaaa atgatcccca      5400
     ctacacggaa gctgcagatc agatgaatat aaggcggaag cgacacacct cgtttcttgc      5460
     caacattcaa tatgacaaac aatttgaaaa aaacggttta cttgattaga cacggacaag      5520
     cccaacataa tgttggacct gatgaagacc acaacattcg tgatcccgtt ttaacttcgg      5580
     aaggtattga gcaatgtgaa gcccttgcta aggaactgga aagcaagcaa attcctatcg      5640
     acggaattgt ttgttcgccc atgcgtcgta cccttcaaac gatggagatc gctttgaaga      5700
     agtacttagc ggagggtggc cccgataagg ttcccgttta tatttcacct tttttccaag      5760
     aggttggaca tttaccttgt gatattggat tagaattgga caagcttaac aagctttacc      5820
     ccaaatacaa cttccaaagc tgccaagacg gtatttaccc tgagaagcgt gacatctatg      5880
     cttccgatgt taccattagc gccattcgct ccaaggaagc tttagaatac cttgctgccc      5940
     ttcctcagca gcaaatcgct gtaatcacac atagtgcctt catcagattc cttttgaaga      6000
     aaatggttaa ggccgctgac attgatttct tacctcccca gctctctttt aagaattgcg      6060
     agttccgtat ctacgatctc gttcagacta ccaccggaga gttgaaactt gtcgagagtt      6120
     cttctgctta agggaagtgc ttgcttcttc aagtacttct tgggtttaaa agaaatcgcc      6180
     tcaataagct cattttgggt attgtgtttt tactttaaat ggttccactc tattaggaac      6240
     tgtttccgcg acttttatcg ttatacttca aatgtgcttt atctcttggt tttagaatac      6300
     tcttattata gaattagaag ttttgcaaat attcttttgg ttagggaaaa atgatatttt      6360
     acaatttttc tttcgtataa agtccttgca cgaacaaatc tttcaaccat ttgcatccga      6420
     gtcaacttaa taaattttag ctttctcaac gaattgtatc aaactgctaa ttagtttcaa      6480
     agtattgaaa catgatttaa gttaattgct agtctatagc gagcaatcac tgttcaaaga      6540
     cctatctaac atatgaactt agaaaaatcg gatgtatttg attaaaacta ttttctacac      6600
     acaattgact aaattatgaa tttctaatgt gacgagtaaa ttgcatattc tcctattgaa      6660
     aggttgaaga tatttagcaa tggaacatgg acttacaata aaaaaaaatc gcctccaaaa      6720
     ttcgggtggc aaccgaagca ttatcgatgg aaatataact acttataaag gtctatatat      6780
     ctataatctt caatatcctg cctagaacac tcatttcttt actttcattt aactagttaa      6840
     agctgtcagt ttccgtattg atttagttgt tcaaacaaaa tctgtttaca gatacttggt      6900
     tgtatatgag tttgttaaaa gattcgcttt actagacttt cggatatgaa tgaccgaggt      6960
     gaattgttta aacccatcaa agtgggaaac atgcttttgc aacatcggat tgtgcatgct      7020
     cctatgacga gattgagagc tactgactat ggaaagatca ccggcctaat ggtagaatac      7080
     tattcccaaa gatctatgat accaggaaca ttgcttattg ctgatgccac atttgtcggt      7140
     gaaaaatccg ggggatttcc taataaccct cggtgcttta ccaaagagca agcagaatct      7200
     tggataccac ttgttgaggc tgttcataaa aataaatcct ttttgtttat tcaattttgg      7260
     cccctcccag gtgaccttaa agatgaatac agaaatgatt tggaaaaaat gcaaaaaata      7320
     acatattcgg attgtccaca agaccctggt ggcttaccag cggggatcca ctcatttgat      7380
     gctgttcaag gcgtggaggt atataagaaa aagtatatgt ctaaaagaga tatccaagag      7440
     cacatacagg actttgttaa tgctgcggat ctggccgtta acatcgctaa agcagacggc      7500
     gtagaaattc accaggtgaa tgggtttctt cttgacagat ttgtgttagg tggttttggt      7560
     gatcaatgtg atcctgaata tcgtggttca attgaaaacc gatgtcgatt tcctttagag      7620
     gttttagaag cagtaacaag aaagattgga caggagcggg ttggctatcg tatatctcca      7680
     ttttccggtt ggatgcaaaa aattgatttc atggaagtca atatttatct tatgagtgag      7740
     atcgctaaaa ggtttcctaa actagcatat attcatgcca tcgagccccg aaaatattgg      7800
     tcgggtcata agttagtctc ttcagaacaa aacaccagct ttttgcaaaa gtattggaag      7860
     ggaccgttta taacggcggg aggatacgat ccagaaacag ctgtgcaagc tgccaatgaa      7920
     cgtggcgtac ttgtcgcgtt cggacgaaat ttcattgcga atcccgattt agtttttcga      7980
     attaagcatc atattcctct taacaagtgg gatcggtcta gcttttattt gccaaaaaca      8040
     gagaaaggat atacagatta tccttttagc aaagagttcc ttcaatcaaa gtgaactttt      8100
     tcatcacaat ttgagtttaa ctggcactga gctattttcg tacatgttta ctaaatcagg      8160
     cgaacgtgtt gaacactagt gaaataagta tatctaatac aggaaattta gtgtatattt      8220
     cgtcagaata tcgtgcggct agctatttcc ataccacagt ttactttagc taaaaatgaa      8280
     cacgcacata cagcagtata cgaaacaagc attaatttag ccgtttattc agggattgta      8340
     tgaaactctg atgattgagt aaccgttaag cgttagctga accaaaaacg tcgtttaagt      8400
     ggtctttata cgcacataca gcgatgtcaa ctttgggatt tttaataaca tcgtttacca      8460
     taaaggttgg caatggcttc atacccagaa actgattcgc tttatggaac gtcagtaggg      8520
     ttccgtctac tcccctccca tcgaaaaaat ttccaacttc ttcaaaagcg gctgcaggag      8580
     cattccaagt gcaagatatc atatagcgat gctcatgaag taagccacct tttccataat      8640
     tttgagttgg atttttactc gaccttccat catttgcata aagttgaccg tatccagcag      8700
     tgaacacttc atccatataa cgctttaact tccatggtgt acccatccac cagccgggcc      8760
     attgataaat aataacattg gcccagagga ttttttcgac ttctgtgttc tcatcatacc      8820
     cttcatcaac gacagtttcc tgaacagtat ggcctagctg aattaatgtg tcttttgcta      8880
     cattgtggag ggttttatta aatttccctt gggaatgagc gaattcttga gcgccgttaa      8940
     ttagcagtat cttcatcagg gtcgtctaaa atttaccaaa aatgacaaat aaatgtatat      9000
     tgttctcgaa aaagaaggtt gttgagtaat ttctttgatg ttaggaatca atttacacag      9060
     taagaataac gaggtatatt aatattttct attgcttggt gttcatgaat caagttatta      9120
     ctaagcaaaa tcttgtgtta taacctttta cgctgattgt acgtttagaa atgtaggtaa      9180
     tcgtcaaatc atctaatgga tttagtcatt tgtaaaaact aataatattc atgcattttc      9240
     actataccgt gggccggttt ctgtgttgca gcttaaaaca atgtgcattt ccatcgtgtc      9300
     attaaatctt ttaaatgaaa aatatcggca aatttctaag agtaaaattg aaatgaggtt      9360
     ttgcatgtga tttttaaaca gcggtctttt aatagaagtc aaaatatatt ttacattaac      9420
     acttatagta gctattgtat ttcaaagtta gttactgacc aaaagttttt tactatgaaa      9480
     tatgtagaag cgtttagttt ctaactaggt atccatgtct ccccttctat tgggatttgc      9540
     aagtgcaatt gggaataaga tctaattctt cctctgatcc attagtttca ttatgttatc      9600
     tttgtaaggt attagcaaaa gatcatcaga acctaataat tggttctcta ttcagaattt      9660
     ggtagatcat tagtgcaaga tttcctccaa taagagaatt accgcgaaca aatctattaa      9720
     gcttcagtat aagctaattg tccaaaaaga ataagttctt taatcacttg aattttatag      9780
     catcgagttt tgaaggggac accatggcag gtttcacaaa aggcctcgag ttgtttggaa      9840
     ctacgttgga agcaaaaaga tagacatgat tacttttata caaacaagac tcattaaacg      9900
     acgtgcgtgt ctactagaaa aggctcactt atataattaa taaaaaaaat ccaaaatttg      9960
     atatattaaa ccgttgttta catattttcc aaatctaaaa aaggttcaag ccaaaaaaaa     10020
     tgctttagga tatgttgaag tgaacattca agccagtgaa atgtaaaagc tcataatttg     10080
     ttctaggtat cgagataacg ttctatttac atagccgatt tgaaaatagc ctttacctcg     10140
     tcatgtgtag gctgaatagg gttagtagca ccacaagcat ccttcatagc gtggtcaacc     10200
     aagacatcaa aatctttttc cttgacacct agatcaacta gatgaggacg aattttaact     10260
     tcaagaacaa gttgactgat gcggtcaaga gctgcttcgg cagtatgctc ttcacaaccc     10320
     aagtgaaaag caatatcacc aaggcgagca tttgctcttg gatccctaga attaaatttc     10380
     tgtacatggg caagaagaac agcgttacag acgccatgtg gaataccgta gaaaccacca     10440
     agttgatgag ccatagcatg aacataaccc aaagatgcgt tgttaaatgc cataccacca     10500
     aggaattcgg cataagccat attgtctcta gcctcttcgt ccttgccgtt gtcgacagca     10560
     cgcttcaaat acttattaac gagttcgatg catttgacag cacaagcatc ggtgatggga     10620
     ttagcagcag tagagacgta agcttcaaca gcatgagtca aagcgtccat accagtagca     10680
     gcggtcaagg aaggaggtaa tccatacatt gtttcaggat cgttaacgga aaggataggc     10740
     atagtatgct tatcgataat agccatttta atatgacggg tctcttcggt gataattgcg     10800
     aaacgagtca tttcagaagc agttcctgca gtcgtattga ttgcaatcaa gggaagttga     10860
     ggtttggagg atttatcaac accttcataa tccgcaattt taccgccatt agtagctaac     10920
     aaagcaatac ctttggcaca atcgtgagca gaaccaccac caattgatac catagaatca     10980
     cagttttcct tcttaacgat ttcgagacct tggttgacat ttccaacggt gggattaggt     11040
     tgaacaccat cgtaaaggtg aacagtgatg ctttgttctt ccaacagagc cttaactttg     11100
     tcatacaaac cgaccttaat aataccagga tcggtaacaa ttaaggtgtt tttgaagccg     11160
     ctcatcttaa tttgcttggc ggcttcagca agacaacctt taccgaaaag gttgaaagaa     11220
     ggtatgtaga atgcgctaac aggcatggct ttcgaagagg ttgattgatg ctttaagcca     11280
     ttagtaaaag attgattaca agaggaatga aagagtgacg gaaagaatcg agcaggcgat     11340
     cgaattaaac gaaatggaga acgaagaatg gacatgttaa aaagaaaatc gcatctaaag     11400
     cttaacctcc gatatttttt agaatcaata atatacaaag tatgaaaaaa aataaataat     11460
     tagccaaacg gaaaagaaat atgtaacaat cggtcaaaaa agtcaagggg gaatgagcct     11520
     taagtagtgt acgaaaattt ctccaatatc aatgtgtaat caattagtgt ctaaaatttc     11580
     gatacttcca ctccttatct cgcttaacga acacttatcg aacatcgatc tttttacaac     11640
     aatttcgcta aatagatctg cagccaactc caacgtcaaa taaatgctaa ggaattaaaa     11700
     gatcttcaaa tgattttcaa aacaaaattg cttgtcacca aaactctttt ccaaacgaca     11760
     tcaaatcacc tccaaactgt cattctttcc gccattatca taaattttac ttaccaaaaa     11820
     gtagaagatc aaatatttct ctacccaaaa ggaattggaa tattctgaag cgtcttgagt     11880
     atgaagagcg ccattatata caattgtctg agtaacaatt ccaagcaata tgaatggtca     11940
     cattccgttt cttttaccct caagttgata ggcagtaagt tcgtcgtaag acatatgtaa     12000
     catttttaga ttcctgggag aacttttcca aaacaaagca acccgaatta ctgcaaactt     12060
     tgtgattttg gcatgcatgc catccaaatg ccaaaaagtg cgttacctta acgttggaac     12120
     aattctcaaa aagggttttt ttcgttattt gacgtgatcg tcgtcgatgc tgattggcag     12180
     taaaacctca agatcttcta gaagatccac ggatttacca tgtttatgtg gatcactgcg     12240
     gctctgtctc caaggggaat atacggtcaa agcaatcgca ttatcgctgg ttcatcttcc     12300
     ggttcttctg gacaattttt ttgcttatcg taaaatcgga atgagaatga ctgctggcaa     12360
     cgtgcctccg gaatttttag cacacattgt ttggcatttg cggcgctgta aaaatttatg     12420
     ttattgtttg taagaggagc atcagagctt agttgaagtg ttgggatgaa tacaaaagtt     12480
     tctgaattgg tttgaaagcg acatctttaa agggatttta tactatttca ctaaaaatta     12540
     aaaatttctc tttgactcaa tgccctttaa aaaaaaatta aaactttttt atatatgaaa     12600
     acacttggga ataattacat gggccttttt tcatgatgat cgaacaaagg ggaagtatgt     12660
     ctaagcaatc ctaaataagt ttatcgtcaa gtaaaagaaa cacaacgttt tattaagaac     12720
     ttgtaaatta acaagctcga tcatatcgaa agtaaaacag catgacagtc ttaacttcat     12780
     acaaattgta ttgtgggccg gattttccag ccccacttga aaagaaggaa aaaagagaga     12840
     aaggaaaaat acggaatatt agttttttaa tagttttgac aaaagggcca atctggaagg     12900
     ttagttcaat ggaaagcacc agttataatg ggtgcatcga aaaccttgac tgtaaattta     12960
     gaaagtcatt cattgaagaa ataatagcct acgaaggttt tggcaaatat atagaggtaa     13020
     tcaattttta aatttttttt ttgtcaaaaa ggaaacatga ttgcaggtaa tcaacatgat     13080
     caaatgtacc tttttttttg gtaatcgaac ccccataacc caagtagtaa ttaaaatcaa     13140
     agaaagtagc aaatgatgga aatggtcaaa cttggatttg attgtttcat aaggtcaaaa     13200
     ttcatctcac aaatgttcgt ttttgtgtta tttaccaata catcattctc ctttaagagc     13260
     aaacaccatt ggatgaagta tttaaaaatc tattgacttt ttaaacccca ttctcctaaa     13320
     tatctgttaa tcgcccgatt gtataggaaa cgacagcata gtgaaggatt ggcgacataa     13380
     actttagtat tcgaatgggc aaacaagaaa acaaattcta acattaaact atttcgagtg     13440
     aaaactatgg ataatttcat tcaataaaac gatggtattg gaataagtgt attccttcaa     13500
     acaaactaaa aaggacagta aaagaaagtt aaaacataaa actttcacag cgtctctgtt     13560
     acataaaaat cagagttgtt agacactata ggtctgtggc taatggaaac atgacaagat     13620
     cacttgatcg tgatttgaaa acaatccatg actcagttga tggttgtttg gatattgtca     13680
     ataagacgag ctttgccaag ccaagcagct gccaaaatta cgacattttt tgtgccagca     13740
     gtaaaaggtt ctaaagtcgt agagtcacag atttccagtt gatcgggaat gaatctacaa     13800
     cgtgatagct cagtattagt ttctgcaatc aacttctcta agtcgccatt gccattactc     13860
     aactcttggg ctaatttttt caaaatttta tataaattgg gagcgatttt tctctcttcg     13920
     gaagttaagt agccatttcg agaactaagt gcaagtccat catctgcgcg cacaattggc     13980
     acttgaatta tttcaataaa gaaattcaaa tcgcggacca tttttttaat gatggctact     14040
     tgttgaaaat ccttttcacc aaagcaggct acgtccggat ttacgatgtg aaaaagcttg     14100
     ctaaccactg tagtaacgcc acgaaaatgg cctggtcgac tcgcaccttc aagcatggtg     14160
     gacagcttag ggacgtcgac aaaagtaatg tcttgagacc cttccggata taactcctca     14220
     acagttggag cataaaccag atcgactccc aggttttgca gctgagagca atcttggtcc     14280
     atggttcgag gatacaagag taggtcttgt ggattattga attgcattgg atttacgaaa     14340
     atactgacaa caaccttttc ggcatgtctt ttggcttcac gaactagaga aaaatgccct     14400
     tcatggagat ttcccatggt gggaacaaaa gcaattcgat ttccatcttt tcgccaatta     14460
     tctacttgct gatgaatcag gagcttctct ttaagaacct gcatgctcaa aatatccaga     14520
     aattttgtat tttatttatt ggaaactgtg ttcttcagca gggtatagac cttgttctac     14580
     ttcgtagatg taacgttgga tagccgtgcg aatgtcccca gccccggaca aaaaattctt     14640
     agcaaatttg ggtgggcggc ctccagtaat tcctaaagca tcatgcatga caagtatttg     14700
     gccatcagta tgctttccgg ctcctatccc gatagtgggt atggatatag ttttagtgat     14760
     ttgttcagct agtgactctg gaatacattc taagacgagc agctgcgcac caaacttttc     14820
     caactgttgt gcattttcaa ttaagcgtgc tgctgcagac tgttccctac cctgtatttt     14880
     ataacctcca aaaatgttta cagactgagg agtcaggcca aggtgtccag caacagggac     14940
     tgatcgttct gtaagtcttt gtacaatttc aaaaatccaa ttccctcctc cttctatttt     15000
     aactatattt gcacctgcac gcattacagt agccgcattt ttacaagcat cctcccatgt     15060
     actgtaactc ataaatggaa ggtcagccat caagaggcga ttaggggcac ctcttcgaac     15120
     actttttgta tgatatgcta tgtcttctac tgacactggt aatgtagtac tatgaccttg     15180
     agcagtcatt ccaagggagt caccgacgag cattacaggc atcccctgtt ctgcgaaaag     15240
     tcgtgaaaaa ctggcatcat atgctgtaat acaagcgaat tttttatttg ctagtttcca     15300
     ttgacgaaga gtggatatag ttatttgctt taatgacatt ttttgttatt ccttttcata     15360
     aggtggtacg tctgtaaaac aagtctagca caattcaacc cagatatttt ctaatatgtt     15420
     aaaaacaagt aatgcatatt aaaaaatgga ctctttactt taaaaataat aatacttata     15480
     agagaaattc ttgcttagga aacctcttgc tcacatactt tgaatatgtc tatgaaaaag     15540
     taaaaatcac tgtgatcctc cagttaaagc atttaacata catggttact ctggtttatt     15600
     tacatacgat tcatataacc tacaaagaat tacaaccttt gaaattcgtt tgtccaattg     15660
     caacggattt ttattcgcaa actaaaatag ctacctgttt aaaaacaact attttaatat     15720
     ttgaatagat atcccatttg atagtggtcg ttcctaaaac aaagtcatta ttttcgcaaa     15780
     ttttttaaga tatcaatgtt tagtaacaca agcaacttat tttactgctc tcttgttact     15840
     catattcatg tcgaatgtat aacattttta agtacaaaaa tcattgaaat tgctaatttt     15900
     ccgtttgtat accaaaaaac ggcttgaaac aactttggag tattttcgca tcaatccact     15960
     ttgcaataat ccctctattt gaattgtgct agtgtgtttc atagtcatac agaaatatgt     16020
     tgatcagctt catgtctgta aactcattat ttgaattctt atgatgaatc gtcagttggt     16080
     aaacacaact gcgaaatacc gatattggag atcattgaca aaaggctaag ctgacaagta     16140
     tctgtaaatg aaaaaattta ggcgcattct cgatttttct gtattccttc aaggtcaatc     16200
     aatccaattg ttttaatcat ttcccaatct cactcctgcg aataatatag tagtgctatt     16260
     ggtgcggctg catgcctatt gattgatcca cgcacgtggt aactctgcta cagggctaca     16320
     agtccgttca tctatttcaa ttcctcctaa acttcataca caaaaagatt tataagatct     16380
     tcacttcttt tgtgaagttt tcaattttat tattttcctt ttgatattca aggtattttc     16440
     gtctttagcg ctacctaata aatttttttt gatcaaaatt ctccatcagg tctgctcttt     16500
     tctttgatac acaccaggat ggctgttcaa aagttatatg aatcgcagag taaattgttt     16560
     cagcccatta aggttggtaa catgcaactt caacatcgaa tggttcacgc accggctacc     16620
     cgtctacgat gcttagataa tggccttgta atgacagatc ttgtgaagga atactacaag     16680
     caacgcagtt cgattcctgg cacattactc attacagaat cattattttc aggcgcaaag     16740
     tcgggaggct ttagtaatat cccttgcttg tacaacgatg aacatgtaga agcttggaaa     16800
     ccaattgtac aggcgatcca tgacaatgat tgctttgtgt ttatacagtt ttggaacctt     16860
     cctggagagc taaaggtcga ttatcttgaa gatcaggaaa ggttggaaaa agttacacaa     16920
     ggggaatgcc caatggatcc taccggattg cctgctgctc taggcagtgc ctactctatt     16980
     tgtggagagg agctgtatgt cgataaattt atgacaaaac aagatataca ggaacacatc     17040
     acaacgtata ctgaagcagc gaaacgagct gttttcggtt gtggtgcaga tggtgttgaa     17100
     gttcatcaag tgaatggatt tcttttggac aaatttgtac taaacggcta tggtgacaaa     17160
     tgtgatccgg aatattgtgg gtctttagaa aatcgtgcta gattttgcct tgaacttcta     17220
     gagtctgtcg tgaatgccat aggtcaagag cgcgttggat ataggatttc tccgttttca     17280
     gatatttgga aagacaagga ttcttttgag gcacacgtgt ttatgataaa aaaaataaag     17340
     gagaggtttc ctaatttggc ctatttacat gctatcgaac ctaggcaata ctggaatggg     17400
     catgtgcata taacgcaaga aaagaataca ttgatctaca aaaacctttg gggggatcca     17460
     tttatcactg caggtggaca tgaccgagac tcggccatac aaatggctga acaagaaaac     17520
     actttagtag cgttcgggag gtattttcta tcaaatccag atctcccatt ccgactcaag     17580
     tataaccttc ccttaaacaa atgggaccgc gcaacttttt atacaaagat gagtcctaag     17640
     ggttatatag actacccatt ttcgaaagaa tttttggata ccaagaaggt tgagtgaatg     17700
     acagcgggta atttcgctag acccttttta gtcatcaaac aacttgttac aggtgcgaag     17760
     taaagagcca gtactagacg actttttttt tccaataatt atttccaaca ttttaagaat     17820
     tacaatactg atactacctg aaaaatattt ggaagcttta ttgtacgttt taagacatat     17880
     tgtttcgcga aagtgtaata acggaacaaa taataaactt cttgtcggag attttcttat     17940
     gtattgctga aataattttt agtttgtttt aatcctgtaa gaatattcat cgttgagttt     18000
     acttttctag ttcaaagctc gcttaactca acctaaattt acaccacgga taaattgtga     18060
     tgtcaatatg caatgaagcc gcgttgataa ttattcagtc ataaatattc aatatgttca     18120
     agtccagata attacacatt atatcttcag aggcttcaat tttttacgaa caacatcaat     18180
     tttttaaaac ctgagcataa tctataattt tataaacgta gttttccgaa acaacgaatc     18240
     actcttttat taatttgcag atcaaatcac tctttcacaa aacaaaatgc tttccttttt     18300
     tacaaaaaat accttgacta aaaggaagct tattatgtta gctttggcta tagttttcac     18360
     cttttttgcc ttcgggctat attttattcc gcacgacgag atttctgttt ttgattttaa     18420
     acttcctgca cttcaatatg aaactacggt gacatctctc gataattttt tgatcggcgg     18480
     aagcacaact ttgtatacag caaccgttaa tcacgaagat ctcaatgaac caaaatcaca     18540
     tgaaatagta atgcttcttg ctagcgatgg aaacgttgga agttttgaat ctaacttact     18600
     agatgattgc tttaaaaatc gtatagagta tgcgaaactt caaaactaca attttgaatt     18660
     cgttaacgtt tccagtctgg tagtgccacc tgtatgggga aagatgcccg caattctaca     18720
     aacaatgcgc aagtatccat ccgcaaaatg gatctggtgg ctagatcagg atgctcttat     18780
     aatgaacaaa aatctgtcct tacaggaatt atttctctca cctgcaatgc tccaaaaatc     18840
     attgcttagg gagcaaccaa ttataaactc tttcggagaa gataatttca gaatcactcc     18900
     agcggcttac tccaaggaaa tgatagaaca aatacaattt ctaatttctc aggatcataa     18960
     cggattgaat gcaggaagct ttttagtacg aaattcaaga tccatcgctt tactaatgga     19020
     tttattgact gatccttctt tggcagatgc aggagtcgtg cgtcatgaac aagatttgat     19080
     cggctatttc attcaaaaac actcgcaggt agcttccatg gttggcattc ttcctcaaag     19140
     atttatcaat gcttttcatg aaggaccccc tacaatgcaa tggcaagaag gagatctagc     19200
     tcttcatttc gctggatgtt gggttgaaaa caaatgcgcc gagttatgga ctaaatacaa     19260
     agataaaata atttaaaagg ctaaatcaat gcccaagtgt cggcgcgtta tagcctctaa     19320
     cattttcaat tgcatttaca gttaatttat tattactatt tatcttttac ttcgttatat     19380
     taatgccgtc ttatttaaac ataaatgatt cgctccataa ataattatga agctgcacat     19440
     ttttacaaat ctaattaatt ttcttaaaaa agaataaatt ctataaaatg cttcaaaaac     19500
     aaccctctag acataaagta tctttttcta aaaaatatta atgtctaaca ctaattaaac     19560
     tatcctgttt ggacctcagg ctagtttaag catcaaaaat tgctaaacgc ttgtgataat     19620
     aattaaaatt ggggtttgtt cataaggtct aatgagtcca taatgaagga gagatgagag     19680
     gtatattaaa atcaaccgca agtccaaaat tatattctaa aaataggctg accgaaagca     19740
     aatcaccgct aacgggattt atagacagac gcaggtaata aagttgtata catagccagc     19800
     aatcaaagaa agctgaagag atctaaacaa tgtgcgttta gacaataagg atagcaagtc     19860
     taaaataaaa ttatggtaat aagttaaaga aattttcaaa tatataacat acaattagat     19920
     tttaacttct aattgtaaaa taaggtcaca atacagaaaa aagaaaggta ttcctccttt     19980
     aatgagtttc atacttatga aaagacagca tttcgccata agcagcatac cagtcagcta     20040
     aatatactgg tgcaaattct gagctaccaa tattccagaa ttttccgtgt gctgttttta     20100
     agagaggacg ttcgtcaatt gagggccaca cgccattgta ataaggatca agacgagtcc     20160
     agggaaacca tccgtccaag gaaaatgcaa gattcaacaa gctttgctcc atcattttgg     20220
     cattctcata catataagga aaccttccga ttttaagtat acggttaaaa tgaagctcgc     20280
     ttggacgtat aagcattaag ccagcattga aataaggagt atcttctgga ggtatactat     20340
     gatgctctcc tctatcagag acggctgcga gaagataagg gtaaaattcg cttcgactgg     20400
     caccatattc tttaaaatcc tcattgaagt gatagacggt atcatcatca ggcttcgtgt     20460
     aggaaggtag ccgtgtatag ttcaaggtat taatttgttg gtacatataa ggagtatcaa     20520
     atatatcatc aatgttcttc atgatcaata tatcactgtc aattacgcaa attttgtcaa     20580
     attgtatttg ttcgaaaatt cgcaacttcg aaaacatttg ttcatatcta gcagatattt     20640
     cttgactaaa tgaggatgta tcgtatacaa tatccgatga agcaatgggg tctataacaa     20700
     tcacagaagc accatccttt cgaaaacgtt caattttcca ctcatctact ccacggagtg     20760
     caaggatatg gatagggtat ttacttttgg tagtaggatg atatttcaat cggtgaatta     20820
     aaaccctagt agcgttgaag tagtaatcct cttcagtaga aggcatagta aacaaactca     20880
     tatacgtata tttgccaggc tcttctttta agacggcatt atcattttcc tcaacaaagt     20940
     tgttttttaa tgaagtaagc cggtcattaa gggtttgctt ataatcgtgt ccgttaaaca     21000
     ctaaggttgt catcacaata atcaaaacca cagaaaacaa caggaatttg taacgcggaa     21060
     gagataaaaa atttgaaagt gaaattcgag acatgataag agattaattc aacgaaccgc     21120
     tgaaacaata gaatttgaga cacgtgaaat tttcgaaagc cttaaaaaaa tgaaaaaagg     21180
     ctctaaagat gactcccttt atgaggatgt taccctctaa aatttattta tttcttttac     21240
     ccttaaacga cttgcgttaa caacccttta aagaaaaaat atccgagatt tatgtttcat     21300
     cacgcgggtt gctctgcatt tgtcaattta ttaccagcac gttgtttgta ccatgtgccg     21360
     cgctatattc agttacagta ttgtaattca aattgtggaa ttgcctttta caaatcctaa     21420
     cgctttgttt tttcacaatc atcttagttt gtgtgtaatg gtgtcaactt tcgagctatc     21480
     tggatgttga aaattatgag cttaagcatg taatagaaat tgacactaat gaattaattt     21540
     ggtgaagttg tttcaaacag tgaaaaatct gactgttagc tggaaaagta ttggaaatac     21600
     catttagctt attggtaaag taaatattgt gtaaatttaa cgaaatatat tttgtcgata     21660
     aatctattca aatattcttt ctccttgacc tgatagacct cattaatcgg aaaatgcttc     21720
     taggtttgta aagacacaag tgtaaacagt gggtgcacag acgtaatgga accaccgtta     21780
     aaaaatacat cttttagact tagcaactaa tctatatctt tataaggcca aaagccagtg     21840
     taatcaatat aaaataagga cataccaata ctttgtaggg ccaaaaaaca agataaataa     21900
     aaacttagta taatccgaca cgaatgattc aataaaactt ctatcagcat ttaacagaaa     21960
     atggcagctg cggtgaaatg caaattatta aaaagattta ttaacgccaa actgttattc     22020
     caatcttcaa tattgcattg gtaaattgcc aaagcaaatt agttgaacca acagaaacag     22080
     cttcaaagtc aatgtgaaat atatacaata tataacaatt attgatggac gattgtgtaa     22140
     aacaaaactc ccagatatct cgctataaaa aactaacctg aaactttgat tgctatggca     22200
     caaccgctat attaattagg tatgtaaaga ttaaaaaata gtaaacatta ttagagattc     22260
     agataaagaa aggaagattg acggaaaatt atacggcgct ttgtttatat atataaaatt     22320
     ttttaaaaca caaacaaatt aaacagacgg atataatgaa taagcaactt agtcaatcaa     22380
     ggcgtaaaac ttttgccata gttcatcgca gcggttttca acccaacatc cagcaaagtg     22440
     aattaccaaa tcaccttttt gccattccat attttccgga ccttcgtgaa aagcatttat     22500
     ttttctttga ggaataaggc caaccagcga agcaagttgt gaatgcttag aaatcaaata     22560
     tccaagcatg tcttgttcat tattggcttt cgcacattct gcaacaacag gatctgtcca     22620
     aatatccaaa aacaaggcag tagcaggtga attacggaac aagatactac ctgcgtttaa     22680
     tccattgtga tcctgtgaga ttatgaccat gagattttcg atatctttta aactataatt     22740
     acttggtgta taacgcaaat ccccgttagc atttataggc cgtttagtga ggatggtatt     22800
     agtaattaag gtcttttgca agttctcagg tttcaaaaag gagtcttgaa gggaaagatg     22860
     ggtattagta ataattgcat cctgatccaa caaccagatc cattccgctt tggggtattt     22920
     cttcatagtt tgtaagacgg cgggcatctt ggaccaaacg gcgggaatag ggaggccagt     22980
     aacattgaca tactcaaagt tgtagttttg tttggtacta tagtcaactc tgttctgtat     23040
     agcttcttca aacgtattag ctccattatt gtaagaagtg tgtccatcac taactagtaa     23100
     taagacaata ttttgactgg caggattttg ctgaggctct gactcgtatg acgcctcgtg     23160
     gaatgtagtg cttgtggcca ccaaatgaga gtctaacggc gccaactcaa acgagtgatt     23220
     aacggatgga gtgccaatag catcggagag catgggtgca atttgctgat catacaactg     23280
     gttaaccttc gacaccaaat caacgtccac aaaatatatc aacgagtata gaaacgcgcc     23340
     agcaatcaag ccgaccgtta aaaataagaa aaaaaaacga cgtggaatcc tggataacat     23400
     aagtgccatc tttaggttat aacaattctt cagtaaatca attagaaata atgaaacaat     23460
     aactggaaaa ctttttttga aaaaaaggct tttccgaaat cttaaacaac cactaaatca     23520
     gattgtatta aggtcttatc gaaacgacct ataaaataac gaacgaaatc tcgagatata     23580
     aaaataaatc aaagggttag aggtatatgc tgatggtaaa aaaaagcttc ctgattgtct     23640
     taatgaggct gaatacgcgt taagcttcct ttgactagct atcgttaatt ttttaaaggc     23700
     tttgttaaat attttattaa cgtcggctcc tttgccgatg gtagagacaa ccgtaacctt     23760
     gcctaaattt ttataaccca gcaaccggca cgttacttgc ttataaaact ttctacgggt     23820
     agctattaga aaaatgaaat ttatggaatg aaaacttagc taaaatattc ggatttaatt     23880
     ttgtgtcact gatttcatca aaatatcttg accttattaa acaactactt cgacttttca     23940
     acaaagagag aggctgacca atatagttga attatacaca tcgctttctt tctgtgaccg     24000
     gatttccatc acaatcgcta ctactattta acaaggttaa caataataaa aaaatcgaat     24060
     aaaagttaac aattatacct atctctaata tactgaacaa aacattagcc agcctttaca     24120
     ctgcagcagc taaaacttat attcccttgc ccatgatact cagcaacaac atcatgaata     24180
     caaaaaagta agtcatccaa ggaaatttat gagttcaaaa aatggaataa agtattacac     24240
     attcactact ttagattgta tagctccagg gtaaactgtc gttccttaat acttttgtta     24300
     cttatgcacc gaattcgact atttcgcatt cattagtgat agacgtgaat caacaaatcc     24360
     aaggggtgta gatagtttat aatttatctt gtaacgcagt ttgtttatca catactctct     24420
     tagaatttga cagtcatgac aacgaccacg gtagcaattg catttcatat gcataatatg     24480
     aaaatacttt ttttttacga tagcttttaa tcggcttggt gaaaccgttg ttaatattca     24540
     aacaacattt tgatgtcttc aattgactga acctgctgct ttccttccga catgcccagg     24600
     gtcccagtaa taaaattttt gcgttcttgt attttgagca tcctttcctc aacagtatca     24660
     cgtacaatat atctcgtcac aaatacaggc ttttcctgtc ctaaacgatg aatacgatcg     24720
     atggcctgtg cttccactga ccagctccac catggatcca taataaaaac atggttggca     24780
     caagtaaggt ttaaaccaac cccgcctgcc tttaaagaga taatcagcac gttaacatca     24840
     ggatc                                                                 24845
//