ID   SPAC589    standard; DNA; FUN; 18342 BP.
XX
AC   AL512496;
XX
SV   AL512496.1
XX
DT   04-JAN-2001 (Rel. 66, Created)
DT   04-JAN-2001 (Rel. 66, Last updated, Version 1)
XX
DE   S.pombe chromosome I cosmid c589.
XX
KW   i norganic phosphate transporter; metaxin 2;
KW   mitochondrial outer membrane protein; phosphatidylinositol metablolism;
KW   spindle integrity WD domain; ubiquitin-like protein.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-18342
RA   Wood V., Rajandream M.A., Barrell B.G., Aert R., Robben J., Weltjens I.,
RA   Grymonprez B., Volckaert G.;
RT   ;
RL   Submitted (01-JAN-2001) to the EMBL/GenBank/DDBJ databases.
RL   European Schizosaccharomyces genome sequencing project, Sanger Centre, The
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail:
RL   barrell@sanger.ac.uk and Katholieke Universiteit Leuven, Laboratory of 
RL   Gene Technology, Kardinaal Mercierlaan, 9
XX
DR   GOA; Q9HDZ4; Q9HDZ4.
DR   SPTREMBL; Q9HDZ2; Q9HDZ2.
DR   SPTREMBL; Q9HDZ3; Q9HDZ3.
DR   SPTREMBL; Q9HDZ4; Q9HDZ4.
DR   SPTREMBL; Q9HDZ5; Q9HDZ5.
DR   SPTREMBL; Q9HDZ6; Q9HDZ6.
DR   SPTREMBL; Q9HDZ7; Q9HDZ7.
DR   SPTREMBL; Q9HDZ8; Q9HDZ8.
DR   SPTREMBL; Q9HDZ9; Q9HDZ9.
DR   SPTREMBL; Q9HE00; Q9HE00.
DR   SPTREMBL; Q9HE01; Q9HE01.
DR   SPTREMBL; Q9HE02; Q9HE02.
DR   SWISS-PROT; P87299; YDN8_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced
CC   by the Sanger Centre.  The sequencing of the S. pombe genome is now
CC   being continued with funding from The European Commission.
CC   Fourteen European sequencing laboratories, including the Sanger Centre,
CC   are participating in the project.
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPBC25H2.01c.
CC   SP (S. pombe), B (chromosome 2), c25H2 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c589 is overlapped at the 5' end by cosmid c16A10, EMBL entry
CC   SPAC16A10, accession number Z97185, and at the 3' end by cosmid c688,
CC   EMBL entry SPAC688, accession number AL355632.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..18342
FT                   /chromosome="I"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c589"
FT                   /map="IL"
FT   misc_feature    1..89
FT                   /note="nominal overlap with SPAC16A10 S. pombe chromosome
FT                   1"
FT   CDS             join(complement(121..777),complement(1..65))
FT                   /db_xref="SWISS-PROT:P87299"
FT                   /label=SPAC589.01c
FT                   /note="SPAC589.01c, very low SIMILARITY:Caenorhabditis
FT                   elegans., Q21148, k02f3.4 protein., (308 aa), fasta scores:
FT                   opt: 111, E():2.4, (23.3% identity in 193 aa)"
FT                   /partial
FT                   /gene="SPAC589.01c"
FT                   /gene="SPAC16A10.08c"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAC19758.1"
FT                   /translation="MKKHKSSIKCFKIDQISQQPETDLVFTKRSECKVKDELFSDKENS
FT                   ILCKQLKELDLVVSSNKEFLNEKTSDQISFLKPRETVVEKKLANGSIWPNETSHLDKSR
FT                   DLSSHSNGLDALAMTPYIVKENNKTHLSPRGNYPSEAEKSCDFYGQPLHFYRENTSPCL
FT                   YGSSLSNVFTEKSSDYRHGLGSPTSLVSSNTASKLHLGRKDIVKLSELRNCINSSKDSN
FT                   QIQELENLLRKEKQRNTE"
FT   misc_feature    complement(66..81)
FT                   /note="ctgaccaagcgaatag, splice branch and acceptor"
FT   misc_feature    complement(115..120)
FT                   /note="gtacgt, splice donor sequence"
FT   CDS             join(complement(4770..4775),complement(4518..4667),
FT                   complement(967..4482))
FT                   /db_xref="SPTREMBL:Q9HE02"
FT                   /label=SPAC589.02c
FT                   /note="SPAC589.02c, len:1224"
FT                   /gene="SPAC589.02c"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAC19759.1"
FT                   /translation="MSVCFKKYVKMRQWPHVLSLRVYASYFLLYNNLPLSSAMVHDGVH
FT                   LISIKTILTDQPCPNTIYYAKYQVQRKDNEDAASLLEDKEAYLRNQDCIVHAKNDLLFV
FT                   YDFQAIPSIPEESSSFMLLNSGAFSRLALFQKDELALLLDLYINFLQGLKKTVLYWLCK
FT                   EYNFVPIYGVLLPLKLHPSFDTQLWNIYGYPVVDLQLSVLSKGHIEFYLKPTRQTVYRL
FT                   SEVDNLVKKLDTVIRLAPTGCLATLTSVHANASAQTVDALKHRYGFSLTTTSKWVGVTL
FT                   ESSALEFSWPLELCFLETSALRMNDDSLSSNLTDLNNLVLPSNVVNNKKELTEFANEEA
FT                   EASDKRKEGFTEKEETADAVVTLVPSHSSSPVNYSINSAKSTPASIKVNEEILVADHNV
FT                   SDDILMEEIDDVGITEADFDYFDLPNVEEKVEMIEPNFANTMTTLDNEEINTSISQSNT
FT                   SPNLNTHENIPKQMEIQSDDRMVTEDLNPYNVEVDIPEISLNISDSKIPTSAYMPSYYS
FT                   AVIFPSSISSIFQKYNYGGKYWCPSPSLSTEDLFESFSVAESVTSTDEDICSTNFIQQD
FT                   FTMEYNHDFFSSSKTPTNISEQSNPDSNYDTLSLAHQVLMNESKSANFDFSFLKSLDLQ
FT                   PTITLGKNDLLNAILSQNLWFRSLPFWKSMTTSFMMSQDVLNFSSYMRKPIRDYLEKIL
FT                   LGESSAVFLSKSPENYLSSINNGHHALNDNPPSQVNFSETLVNFSQPPRVLLKYNEKKL
FT                   SLDSSAPENWISLCLQPYGESKDFEVFLLSSKSPDVSSKAISFFYDVQLAYENCKLGKL
FT                   NLSETSINERVMGFSTNINETDNYDDNETTQSDTATSYEQLASVCVNELSGKNVLFFYF
FT                   LEDDSEKLLKACQHFICVKDSIKRLGDNKFEDKSLRICTIPNSIFDSPNSHTTNSNSFF
FT                   TKVSLDIYNNDPLLMDGSLKRREPAFLLKKPLLSTLNYQLKDINPRSSALGEYALHVTY
FT                   TTVEEHLLICNWNDSYGEFETERRYFLQDLEIEDALQQILEVTFTFLNSMHMDWIVIVM
FT                   KIGEMSDAEYLFWDQAIIPENLQGNVSLTVGYCSAEHGPGSTSKVFSRIPYSASSTVIR
FT                   NNSSHELSLVAFIREMAMPVPNDEFKKISTILARGYLALDEDESYLPLLSIHLLISRNH
FT                   DPYLMLNLILKHYLSMIYLQFRTYVSFSSLPLHISTVLYQKQLLQFMASDITHPVTS"
FT   misc_feature    complement(4483..4502)
FT                   /note="ataacatgataaattaaaag, splice branch and acceptor"
FT   misc_feature    complement(4512..4517)
FT                   /note="gtaatt, splice donor sequence"
FT   misc_feature    complement(4668..4686)
FT                   /note="ttaacagtaaaagtatcag, splice branch and acceptor"
FT   misc_feature    complement(4764..4769)
FT                   /note="gtatat, splice donor sequence"
FT   CDS             join(complement(5375..5722),complement(5153..5311))
FT                   /db_xref="SPTREMBL:Q9HE01"
FT                   /label=SPAC589.03c
FT                   /note="SPAC589.03c, len:169, SIMILARITY:Plasmodium
FT                   falciparum., O96229, hypothetical 78.6 kda protein., (665
FT                   aa), fasta scores: opt: 182, E():0.00088, (28.0% identity
FT                   in 161 aa)"
FT                   /gene="SPAC589.03c"
FT                   /product="hypothetical protein"
FT                   /protein_id="CAC19760.1"
FT                   /translation="MDLSLFSDIKDVVERDMKKNSKVVENSSARSLKNKTEENKTIDKH
FT                   KSSVGPKEPKSSLEKPKANRKRKQSYGLLHDIKELGGTEEDLELIEDVESDEELEFEEP
FT                   NRKQPKKDGTDAFANELNLFAKKLGFSKNSFDARALDTESEDETEIEKSSSENSDSVDV
FT                   DSDDE"
FT   misc_feature    complement(5312..5330)
FT                   /note="ctaatatcctctgttttag, splice branch and acceptor"
FT   misc_feature    complement(5369..5374)
FT                   /note="gtaagt, splice donor sequence"
FT   CDS             join(5999..6559,6639..6893)
FT                   /db_xref="SPTREMBL:Q9HE00"
FT                   /label=SPAC589.04
FT                   /note="SPAC589.04, len:272, SIMILARITY:Homo sapiens,
FT                   O75431, metaxin 2., (263 aa), fasta scores: opt: 220,
FT                   E():2.1e-07, (29.2% identity in 216 aa)"
FT                   /gene="SPAC589.04"
FT                   /product="mammalian metaxin 2 homologuue; putative
FT                   mitochondrial outer membrane protein putative component of
FT                   a preprotein import complex"
FT                   /protein_id="CAC19761.1"
FT                   /translation="MGGLTKFSSYFHSIFSRFPLITFSNPYPGENEDYKTKTVMYLTMW
FT                   NSDLNSEALDVNSLQWQTWAKLNDPSIVFLNVSNHASPDEKVPFIQIESRKLVLNPSLL
FT                   QYFLKDESTLQQISPWMSLLINQVETAILLTMYLDNENFSEIQKKWLPNMSWPLNIIKS
FT                   IGLPSQIKRKICLQLNESTLDFDAILEDASKAFSALSELLGSDKWFFNNESPSFLDVSL
FT                   FAHAEIINHLPLKNDQLKVVLGTHKNLTDLTTRVRTLAGYTSAGPIALR"
FT   misc_feature    6560..6565
FT                   /note="gtacgt, splice donor sequence"
FT   misc_feature    6625..6638
FT                   /note="ctaacaaagcttag, splice branch and acceptor"
FT   CDS             join(complement(8370..8408),complement(8175..8323),
FT                   complement(7189..8041))
FT                   /db_xref="SPTREMBL:Q9HDZ9"
FT                   /label=SPAC589.05c
FT                   /note="SPAC589.05c, len:347, SIMILARITY:Neurospora crassa.,
FT                   CAB98246, conserved hypothetical protein., (372 aa), fasta
FT                   scores: opt: 997, E():0, (46.3% identity in 352 aa)"
FT                   /gene="SPAC589.05c"
FT                   /product="conserved hypothetical protein; putative
FT                   glycoprotein"
FT                   /protein_id="CAC19762.1"
FT                   /translation="MSRVLQDAEFISLNSNDVKVNKGGCAAVATWIKEKLDSLGPQFAE
FT                   WQNHELHPKTRDVSTLDWIFLVDILNFSFWSDVDVEDSGKHSKRFSIEYKGKLYTGYWS
FT                   LCAAINKALDAGIPITSPAFYADEKQCPDTLIASVFDSATVEKIPLLEERIRIMRASGR
FT                   VLVDSYHGSYCGLLKKCHNQAQRLIKLLLADFPDFRDVSVYKGRECYMLKRAQILVAET
FT                   WACFQGQNYGRFDDIDSITMFADYRVPQILWQLGCLSYSSDFKKRLLKNELIAHNDPME
FT                   IEMRGCSIWAVEKILQNINRKDVNAITIDFFLWDLAKEWQAKGYKPSTQVDEVTIPCIR
FT                   VRSIYY"
FT   misc_feature    complement(8042..8059)
FT                   /note="ttaacgtcaaatctttag, splice branch and acceptor"
FT   misc_feature    complement(8169..8174)
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    complement(8324..8343)
FT                   /note="ctaacatgaacgattgaaag, splice branch and acceptor"
FT   misc_feature    complement(8364..8369)
FT                   /note="gtaatt, splice donor sequence"
FT   CDS             join(complement(9600..9611),complement(8861..9457))
FT                   /db_xref="SPTREMBL:Q9HDZ8"
FT                   /label=SPAC589.06c
FT                   /note="SPAC589.06c, len:203, SIMILARITY:Saccharomyces
FT                   cerevisiae, PH88_YEAST, inorganic phosphate transporter
FT                   pho88., (188 aa), fasta scores: opt: 440, E():1.3e-21,
FT                   (40.0% identity in 190 aa)"
FT                   /gene="SPAC589.06c"
FT                   /product="probable inorganic phosphate transporter; yeast
FT                   pho88 homologue"
FT                   /protein_id="CAC19763.1"
FT                   /translation="MNAQVLNLVAALGVMQYSKKLDFTDPQIVYYARAAYVISNTIIFG
FT                   VYAIIQARINANNDETPLVYEEPAPPFSGQSNGKLVTTTVKEYDSEQLQKAKRSTMMGV
FT                   AIMAFMHLYMGYAQPLVIQSILPLISLFTNNLVSIYIFNKAAEGSLSRPFAPPAGLFGG
FT                   GNKPAAAVTGTSSNSNNASAKSDGPTITELNENETEKSS"
FT   misc_feature    complement(9458..9477)
FT                   /note="ctgacaaaatcgaaatttag, splice branch and acceptor"
FT   intron          complement(9458..9599)
FT                   /note="confirmed by mRNA"
FT   misc_feature    complement(9594..9599)
FT                   /note="gtaagt, splice donor sequence"
FT   CDS             join(complement(11763..11800),complement(11505..11578),
FT                   complement(11333..11439),complement(11111..11270),
FT                   complement(10325..11045),complement(10235..10256))
FT                   /db_xref="SPTREMBL:Q9HDZ7"
FT                   /label=SPAC589.07c
FT                   /note="SPAC589.07c, len:374, SIMILARITY:Neurospora crassa.,
FT                   CAB98219, conserved hypothetical protein., (421 aa), fasta
FT                   scores: opt: 836, E():0, (41.8% identity in 407 aa)"
FT                   /gene="SPAC589.07c"
FT                   /product="WD domain protein; conserved hypothetical
FT                   protein; highly similar to S. cerevisiae  YFR021W"
FT                   /protein_id="CAC19764.1"
FT                   /translation="MHFFVRKYRGKAALLSIGTFDGYKIYNCDPFGKCFHKIQGATSIV
FT                   EMLFSTSLVALVEKDDGNNRKLKLINTKKSTTICELTFPTPLLAVKLNRKRLLAVLEEQ
FT                   IYVYDISNMLLLHTIETTSNVFAVCALSPNSENCYLAYPDSRDHEPRTEGESSSPNVSN
FT                   SAVSGQVILWDVINCKQITKIEAHKDSLACLAFNSDGTMLATASDNGRIIRVFAIPSGQ
FT                   RLYQFRRGSLPAQIYSIAFHPDSSLLTVTSSTQTVHIFRLKEVYSNLERQGLLPSSPPP
FT                   KESLLRRSSRSLIGTVGGYLPQSVSGMLDPERDFAYAHIPGDKVTSIAAFGPDNTIVNV
FT                   ATYDGNLYSFRVNLRTGGECAMVNHFCVGLTAA"
FT   misc_feature    complement(10257..10272)
FT                   /note="ttaaccctttatctag, splice branch and acceptor"
FT   misc_feature    complement(10319..10324)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(10789..10884)
FT                   /note="Match to PF00400 WD40, WD domain, G-beta repeat
FT                   Score 23.42"
FT   misc_feature    complement(11046..11065)
FT                   /note="ctaattctttattgtaacag, splice branch and acceptor"
FT   misc_feature    complement(11105..11110)
FT                   /note="gtaagc, splice donor sequence"
FT   misc_feature    complement(11271..11283)
FT                   /note="ctaacgagtgtag, splice branch and acceptor"
FT   misc_feature    complement(11327..11332)
FT                   /note="gtaagc, splice donor sequence"
FT   misc_feature    complement(11440..11453)
FT                   /note="ctaacctaatttag, splice branch and acceptor"
FT   misc_feature    complement(11499..11504)
FT                   /note="gtaggt, splice donor sequence"
FT   misc_feature    complement(11579..11591)
FT                   /note="ctaatacttgtag, splice branch and acceptor"
FT   misc_feature    complement(11757..11762)
FT                   /note="gtatgt, splice donor sequence"
FT   CDS             complement(12266..12733)
FT                   /db_xref="SPTREMBL:Q9HDZ6"
FT                   /label=SPAC589.08c
FT                   /note="SPAC589.08c, len:156, very low to
FT                   SIMILARITY:Saccharomyces cerevisiae, YG2Y_YEAST, YGR113W
FT                   required for maintenance of spindle integrity during
FT                   mitosis, (335 aa), fasta scores: opt: 114, E():0.62, (29.9%
FT                   identity in 67 aa)"
FT                   /gene="SPAC589.08c"
FT                   /product="similarity to a region of yeast dam1 maintenance
FT                   of spindle integrity during mitosis"
FT                   /protein_id="CAC19765.1"
FT                   /translation="MEKYQKATQNPLENVDNVKIESENAIPSNLQAFTKSLAVLDDNVS
FT                   EFRKRMNHLSATKQILDNFNESFSSFLYGLQINAFCVDYENAPLSESFLLQAKKDQFKA
FT                   TLMTRTGHSISDPPYDGGVISHDPNFATADETFATNDTSFIERPETYSASR"
FT   CDS             12732..13898
FT                   /db_xref="SPTREMBL:Q9HDZ5"
FT                   /label=SPAC589.09
FT                   /note="SPAC589.09, len:375, SIMILARITY:Schizosaccharomyces
FT                   pombe, YAS2_SCHPO, hypothetical 51.5 kda protein c3h8.02 in
FT                   chromosome i., (444 aa), fasta scores: opt: 545,
FT                   E():6.2e-29, (33.6% identity in 321 aa)"
FT                   /gene="SPAC589.09"
FT                   /product="putative phosphatidylinositol metablolism"
FT                   /protein_id="CAC19766.1"
FT                   /translation="MFSRLWVRCRCSTALSAAAAGTFFFRRSQKQPEPETVDEKVSFES
FT                   YSPLKLMIQKTWPRFQEHKEYRESFIRLAKCDSPDAILVRFLASCNNDSHEASQKLINT
FT                   LQWRVDTGVERIVERGELYAKETNDDQFLEQLRTGKVTMLGRDLSDRPICYIQVHLHQP
FT                   SKLTQNSLREMTVWVMETMRLFLRPQKTLKDSMDSPQNVNVLFDLSNFSLHNMDYSFVK
FT                   YLASCLEYYYPQSLGVCILHKSPWIFRSVWNIIKGWIKPEIAAKIVFTQSANDLEKYID
FT                   YSVIPTSLGGGNKKIFQYIEPVEHENDAVIEDSAEKTAALARYYAYFSEWEQHSLNWAK
FT                   LDDDDAQNEKVRLCCDAAGTNFANCYWNVDKYIRARTVYDRLKWIGNV"
FT   misc_feature    13083..13604
FT                   /note="Match to PF00650 CRAL_TRIO, CRAL/TRIO domain. Score
FT                   105.11"
FT   misc_feature    13829..13992
FT                   /note="208 (+1) 29755 29918 AC018897 AC018897 Homo sapiens
FT                   clone RP11-575J11, complete sequence."
FT   CDS             complement(14320..14772)
FT                   /db_xref="GOA:Q9HDZ4"
FT                   /db_xref="SPTREMBL:Q9HDZ4"
FT                   /label=SPAC589.10c
FT                   /note="SPAC589.10c, len:151"
FT                   /gene="SPAC589.10c"
FT                   /product="ubiquitin-like protein identical to
FT                   spac6g10.11c."
FT                   /protein_id="CAC19767.1"
FT                   /translation="MQIFVKTLTGKTITLEVESSDTIDNVKSKIQDKEGIPPDQQRLIF
FT                   AGKQLEDGRTLSDYNIQKESTLHLVLRLRGGGKKRKKKTYTTPKKIKHKHKKVELAVLK
FT                   YYKVEDDGSVKRLRRECPNCGASTFMANHKDRLYCGRCHLTLKLEA"
FT   misc_feature    complement(14329..14472)
FT                   /note="Match to PF01599 Ribosomal_S27, Ribosomal protein
FT                   S27a Score 119.49"
FT   misc_feature    complement(14545..14772)
FT                   /note="Match to PF00240 ubiquitin, Ubiquitin family Score
FT                   194.12"
FT   CDS             join(15066..15204,15498..15907)
FT                   /db_xref="SPTREMBL:Q9HDZ3"
FT                   /label=SPAC589.11
FT                   /note="SPAC589.11, len:183, SIMILARITY:Homo sapiens,
FT                   DS1_HUMAN, ds-1 protein., (206 aa), fasta scores: opt: 232,
FT                   E():2.2e-08, (34.6% identity in 136 aa)"
FT                   /gene="SPAC589.11"
FT                   /product="similar to human ds-1 protein which shows
FT                   modulated expression during colon carcinoma cell
FT                   differentiation"
FT                   /protein_id="CAC19768.1"
FT                   /translation="MFANFRNCFKIKNSRLIYDNINKCLLTKEETNQLLKFIHLKWKPA
FT                   KDQVQISFSRSSGPGGQNVNKLNTKVIVNLPFKQLESCIPMFLINHFKTCEMLRNYRIQ
FT                   NGIKIYSQKTRSQHKNIEDALNKISDLLNKSAETLYVPDTPPEKIARISILKKESNEKR
FT                   LSEKKYKQKKKTQRRITMD"
FT   misc_feature    15205..15210
FT                   /note="gtatgt, splice donor sequence"
FT   misc_feature    15484..15497
FT                   /note="ttaactattgatag, splice branch and acceptor"
FT   CDS             join(16093..16215,16400..18342)
FT                   /db_xref="SPTREMBL:Q9HDZ2"
FT                   /label=SPAC589.12
FT                   /note="SPAC589.12, SIMILARITY:Saccharomyces cerevisiae,
FT                   YCQ7_YEAST, hypothetical 107.9 kda protein in pol4-srd1
FT                   intergenic region., (953 aa), fasta scores: opt: 1366,
FT                   E():0, (37.9% identity in 644 aa)"
FT                   /partial
FT                   /gene="SPAC589.12"
FT                   /gene="SPAC688.01"
FT                   /product="hypothetical protein similar to yeast YCR017C;
FT                   integral membrane protein involved in drug sensitivity"
FT                   /protein_id="CAC19769.1"
FT                   /translation="MTEKTSSLVFSAQYVALVHTICSFAAFFIPLALALYTHYYQVVKN
FT                   EFYGYPEEWFPSVSATIGDWYPERSVFQWLIALTATPRLLVLLLWFTLSGISRPSVIIT
FT                   TALGVLRTALCGGWVYVTSTDDHDWHDIFMIGYLISNAPWFILVSKCSPVNSMASRIRN
FT                   IGSALFVLTIFPLIYWYIQHKFKHIPGAYTVYAFFEWSLILWDILFDSALYWDFKPLVF
FT                   NLHTSKTYSNPSSFATRKKEKGEHLSYAEAAAVGTQAKNIKKDSNVKCSKKQILFSLLY
FT                   FSSEVYLSFVFWSVLTSLGLLVWYFPLWHMGISGYEACILFELSPFLLGIPLLRKFASK
FT                   VPVIFLFLNVIGIAAYKLEDPVHRLFVTAFSVCCECLAWTSLFSNISPENLAIERKIST
FT                   FLFGLLASSIAKYSFFSNNPIWPILNETNGGKQIPALIVGIIACLIFAIFHVQQTTANA
FT                   VEHFKLRKITALSAALSLGTVLFCLHTFLCDSTVLMTWSWDGYPIKGPQPYPHGAVSIV
FT                   VSICAVLVAPYLYQSGAFMLIGFVLACFGSYFMYINHGWCSYLGGLIFTSYVLIYSFAS
FT                   IRISSFYSPAKVWGGAFLVYILYSLAHVWVVAYEFVPGGPILRERTSYILIFIGWNLAA
FT                   LVPAYSGESKEPNKADSSVVDIKQSDSSYRRRSFKKSLLTGFCLALMALKFAI"
FT   misc_feature    16216..16221
FT                   /note="gtaaat, splice donor sequence"
FT   misc_feature    16382..16399
FT                   /note="ctaacattatatttgcag, splice branch and acceptor"
FT   misc_feature    17913..18342
FT                   /note="nominal overlap with SPAC688 S. pombe chromosome 1"
XX
SQ   Sequence 18342 BP; 5928 A; 3248 C; 3270 G; 5896 T; 0 other;
     tgttcagtat tccgttgctt ttcttttcgc agtaaatttt ctagttcctg aatttgatta        60
     gagtcctatt cgcttggtca gttatgatca tgattacatt ttttaaatac acccacgtac       120
     tttcgatgaa tttatacaat tccttaattc cgacaatttg acgatgtctt tgcgacccaa       180
     atgtagttta gatgcagtgt ttgacgacac tagagaggta ggtgatccta atccatgtct       240
     ataatcactc gatttttctg tgaaaacatt agatagtgaa gaaccataca agcaagggga       300
     cgtattttcc ctataaaaat gtaatggttg accatagaaa tcacaacttt tttcagcttc       360
     tgaaggatag ttcccccttg gcgataaatg agtcttgttg ttttccttga caatatacgg       420
     tgtcatcgcc agggcatcta gcccatttga atggctcgag aggtccctag atttatctaa       480
     atgggaagtt tcattaggcc aaatactccc atttgctaat tttttttcaa ctactgtttc       540
     tcttggtttc aaaaacgaaa tttgatccga tgtcttttcg tttagaaact ctttgtttga       600
     agaaacaact aaatctaatt ccttcaactg tttacataag attgagtttt ccttatctga       660
     aaatagctca tcttttactt tgcattccga ccttttagta aaaaccaaat cggtttcagg       720
     ttgttgagat atttggtcaa tcttaaaaca cttaattgag gacttatgtt tcttcattat       780
     gttttgcgtt ggctaatttc atggttaaaa atggcggaat atgaaatagt cgacagtaaa       840
     caaacactgt gttttcacta tgtcaacctt cccaatctag taaacaaaaa cgataacaag       900
     agtaaaccaa ttttggcaca agcgcattat aaacttatac tgtataaatt aataataccc       960
     caaaaactaa gaggtcacag gatgtgtaat gtctgatgcc ataaactgca atagttgctt      1020
     ctggtataaa acggtagaaa tgtgtaatgg gagtgaagaa aaagaaacat acgttcgaaa      1080
     ctgtaaataa atcatactta aataatgttt taaaataaga tttaacatta aataaggatc      1140
     atgatttcga gatatcaaaa gatgaatgct taacagtggt aaataagatt cgtcctcgtc      1200
     taatgctaag tatcctctag ctaagattgt agaaattttc ttaaattcat cgttcggcac      1260
     aggcattgcc atttctcgga taaacgcaac caaagagagc tcatgactac tattattacg      1320
     aataactgtg cttgaagccg aatatggaat ccttgaaaac actttcgaag ttgagccagg      1380
     tccgtgctct gctgagcagt aaccaactgt aagagaaaca ttgccttgta agttttcagg      1440
     tattattgct tgatcccaaa acagatactc tgcgtcagac atctcaccaa tcttcatgac      1500
     gattactatc caatccatgt gcattgagtt aaggaacgta aatgtgactt ctaaaatttg      1560
     ctgtaaagca tcttcaattt caaggtcttg gagaaaatag cgtctctcag tttcaaattc      1620
     tccataggaa tcattccaat tgcaaataag caagtgctct tcgacagttg tatacgttac      1680
     atgtagcgca tactctccca aagctgaaga tctgggatta atatctttaa gctgatagtt      1740
     aagagttgat aacaagggct ttttcaggag aaaagccggt tcacgtctct ttaatgaacc      1800
     atccatcaat aaaggatcat tattataaat gtcgagtgaa acttttgtaa aaaaagagtt      1860
     cgaatttgta gtatgcgagt tgggtgaatc aaaaatagaa ttcggaatcg tgcatattcg      1920
     taatgattta tcttcaaatt tattatcccc aagtctcttg attgagtcct ttacgcatat      1980
     aaaatgttga caagccttta aaagtttttc ggaatcatct tctaaaaaat aaaaaaaaag      2040
     tacgtttttt ccgcttaatt cattaacaca aacactcgct agttgttcat aagaggttgc      2100
     tgtatcgctt tgagttgttt cattatcatc ataattatct gtttcattaa tatttgtact      2160
     gaatcccatc actctttcgt taatagaagt ttcagataaa ttcagttttc caagtttgca      2220
     gttttcataa gccagctgaa catcataaaa aaagctgata gccttgctgc ttacgtcggg      2280
     agatttggaa gagagcaaaa aaacttcaaa atctttgctc tcaccatacg gttgaagaca      2340
     taaagatatc caattctctg gtgccgaaga atctaaagac aacttttttt cgttgtattt      2400
     gagcaaaaca cgaggaggtt gggagaagtt taccaacgtt tcagaaaagt taacttggga      2460
     tggaggattg tcatttaatg cgtgatgccc gttattaatc gaggacagat aattttctgg      2520
     gcttttgctc aagaaaacag ccgaactttc acctaacaat attttctcta aataatccct      2580
     aataggcttc cgcatgtacg aagaaaagtt taaaacatct tgagacatca tgaaactggt      2640
     agtcatgctt ttccaaaaag gtaacgatct aaaccataag ttttgagaca aaatagcgtt      2700
     taacaagtca ttttttccca aggtaatagt gggttgtaaa tctaacgatt ttaaaaaact      2760
     gaaatcaaaa tttgctgact tggattcatt cataagaacc tgatgtgcta acgatagcgt      2820
     atcataattt gaatcggggt tactttgttc tgagatatta gtgggtgttt tagaagatga      2880
     aaaaaaatcg tgattatact ccattgtaaa atcttgttgt ataaagtttg tagagcagat      2940
     gtcttcatct gtactagtta ccgattcagc gaccgaaaat gattcaaata aatcttcagt      3000
     tgacaaagaa ggagaagggc accaatattt accaccatag ttatacttct gaaaaatact      3060
     ggagatagac gagggaaaaa ttaccgcaga atagtatgaa ggcatatacg cagatgtagg      3120
     gattttagaa tctgaaatat ttaaagaaat ttcaggaata tcaacttcga cgttgtatgg      3180
     atttaaatct tcggttacca ttctatcatc cgattgaatt tccatttgct ttggaatatt      3240
     ttcgtgagta ttcaaatttg gactggtgtt tgattgagag atggaagtgt tgatttcctc      3300
     attatctaag gttgtcatag tatttgcaaa attaggctca atcatctcaa ctttttcttc      3360
     aacgttaggt aagtcaaagt aatcaaaatc agcctctgtt attccaacat cgtctatttc      3420
     ctccattagt atgtcatctg aaacattatg atcagcaaca agtatctctt catttacttt      3480
     tattgaagca ggtgtagatt ttgcagaatt tatcgaataa ttaacgggag aagaactatg      3540
     agaaggaacc aaggttacaa cggcatcagc agtctcttcc ttttctgtaa aaccttcttt      3600
     tcttttatct gaagcttccg cttcttcatt tgcgaactca gttaattcct ttttattgtt      3660
     tacgacgttt gaagggagga ctaggttatt caaatctgta aggttgctag ataatgaatc      3720
     atcattcatt cgaagggccg acgtttccaa aaagcaaagt tctaaaggcc aggaaaattc      3780
     taatgccgaa gattctaagg taacacccac ccactttgaa gtagtcgtaa gagagaatcc      3840
     atagcggtgt ttcaatgcat caacagtttg agcagatgcg ttggcatgca cagaggttaa      3900
     tgttgccaaa caaccagtcg gggctaaacg aatgacagtg tctaactttt taaccaaatt      3960
     atccacttcc gacaaacgat ataccgtctg ccttgtaggc tttaagtaaa attctatatg      4020
     gcctttcgat aagacagaaa gctgtaaatc cacaacagga tatccatata tgttccagag      4080
     ctgggtatcg aaagaagggt gtaattttaa aggaagaagg acaccataaa ttggaacaaa      4140
     gttgtattct ttgcacagcc aatacaacac cgtttttttc aatccttgaa gaaagtttat      4200
     atacaggtct aatagaagag ctaattcatc tttttgaaaa agagctaatc tggaaaatgc      4260
     acctgaatta agtagcataa aagaagatga ttcctcagga atagatggaa tggcttgaaa      4320
     atcatataca aaaagtaagt cattcttcgc gtgaacaatg caatcctgat ttcgtagata      4380
     agcttctttg tcttctaaga gggaagcagc atcctcattg tcctttcgct gaacctgata      4440
     cttcgcataa tatatagtgt tagggcaagg ctgatcagtt agcttttaat ttatcatgtt      4500
     ataatagaaa taattacaat tgttttaata ctaattagat gaactccatc atgtaccatg      4560
     gcagaggata atggcagatt attatataag aggaagtagc tagcgtacac gcgtaaagaa      4620
     agcacatgcg gccactgtct cattttaaca tatttcttaa aacacacctg atacttttac      4680
     tgttaataat aaaataaaca aacattaaac taacggttta gtatgcaaat aagcataaat      4740
     gcttcgaaat tgatgaagga aatatatact gacatataat gtttatatta atcccgtaat      4800
     gaccgctatt ttaataaaaa aagaatgctc cgccttaaat tcctatcctt actttacaaa      4860
     taattaaaat gaatgaaagt gtagcaataa aggtccaaca caattgcaac tccttcaggt      4920
     aatatgtatg aacctatccc tcagtataat gttagttaaa cattacattc ccttaagact      4980
     cctcttgaat gatggtttaa acaactcatg agtgatggca tctgaaaagt gaacgagaag      5040
     attacagaga aattgggatt ccccaatcag ttttaacaga tacactcatt gcttataaag      5100
     ttataataag aaggaaaatt tttaaataaa taaactagtt gtcaagcgtt ttttactcat      5160
     catccgaatc gacatcaact gaatcagaat tttcagacga acttttttcg atttcggttt      5220
     catcttctga ctcagtgtct agagcacgag catcaaagct gtttttagaa aagcccaatt      5280
     ttttggcgaa caaattcaac tcatttgcaa actaaaacag aggatattag aaccttttga      5340
     aagaagtaat taagaaacat cgatattgac ttacagcatc agtcccatcc ttcttgggtt      5400
     gtttacgatt gggttcttcg aattccaact cttcatcgct ttctacatct tcaatcagct      5460
     ccagatcctc ttcggtacct ccgagttctt taatatcatg gagtaaacca tacgattgct      5520
     ttcttttccg attcgcttta ggcttttcca atgatgattt gggttcctta ggaccaacgg      5580
     aacttttatg tttatcaata gttttgtttt cctctgtttt gttttttagt gatctagcag      5640
     aagaattttc cacaactttt gaattttttt tcatgtccct ctcgacgaca tccttgatat      5700
     ctgaaaataa agacaaatcc atattatgat ttatgtcaaa taaaataaat acaatctttt      5760
     gtcgagttta tcgattatta gaggatgtga aaatccaacg caaaatagaa aagtgtgtat      5820
     gcagaattaa tgcttggtat agtagaaaca acagaatatt ttctcctact acaatatagg      5880
     tagaaatttg aagaaattgc acgctttacc acttaatcta acaatttcgc taagcacact      5940
     attgatggta ttggtgtaaa ctctttagaa ttagcaaact tagtgacaag tgaaaaggat      6000
     gggcggtcta acaaaatttt cgagttattt tcattccatt ttctcccgct tccctttaat      6060
     aacgttttct aatccttacc cgggcgaaaa tgaagattac aaaacgaaaa cagtcatgta      6120
     tttgactatg tggaattccg acttgaactc agaggctctg gacgttaata gtcttcaatg      6180
     gcaaacctgg gcaaaattaa acgacccttc aattgttttt ttaaatgtgt ctaaccacgc      6240
     ctctccagat gagaaagtac cttttattca aattgaatct cgaaaattag tcctcaatcc      6300
     atctctttta caatattttt taaaggatga gtcaacactg cagcaaatct ctccttggat      6360
     gagtttgctg ataaatcaag tagaaacggc aattctctta actatgtatt tggacaacga      6420
     gaacttttct gaaattcaaa aaaaatggtt acctaacatg tcttggcctt taaatattat      6480
     taaatcaatc gggttacctt ctcaaattaa acgaaaaatt tgtcttcagt tgaacgaatc      6540
     aactcttgat tttgatgcgg tacgtttaat aatttttgat agcagttagt cttctagacc      6600
     gagcattttg aagcatgatt tgtactaaca aagcttagat tttagaggat gcttcgaagg      6660
     cgttttcagc tctttcagaa cttttaggat cggacaaatg gtttttcaat aacgaatcac      6720
     cttctttctt agatgtttct ttgtttgctc atgcagaaat tatcaatcat ttacctttaa      6780
     aaaacgatca attaaaggtt gttttgggga cacacaaaaa tttaactgat ctcacaacgc      6840
     gagttagaac tctcgctggt tatacatcgg ctggacccat tgctcttcgt taacatttta      6900
     attaattgag catagcccaa cgaaatttta tttctttgat tgctttgacc gaagttcccg      6960
     atattattat tttattttta aacgtggtta taatgtcaaa tgcattttct cattaatact      7020
     agctttcaca taatgctaac attaacttta ccatgttttt ccgttaattt atttcagctt      7080
     gtttttagta ctttctcact ctatgttaaa aagagaataa attaacaata ggtcaatatt      7140
     atataagtat attttttcaa atgccaccag cataagccta aatactttct aatagtatat      7200
     acttctcact ctaatacaag ggattgtaac ttcatcgacc tgagtacttg gtttataacc      7260
     cttagcttgc cactctttgg caagatccca tagaaaaaaa tcaattgtga tagcattaac      7320
     atcttttctg ttaatgtttt gaagaatctt ttcaacagcc caaatgctac atccacgcat      7380
     ctcgatttcc ataggatcat tatgagctat caattcattt tttagcaaac gctttttaaa      7440
     atcagaagaa tagctcagac atcctaattg ccacaatatc tggggaacgc gatagtcagc      7500
     aaacattgtg atagaatcga tatcgtcaaa tcgaccgtaa ttttgtccct gaaagcaagc      7560
     ccaagtttct gctaccaaaa tttgagcacg tttgagcata taacattctc ttcctttgta      7620
     aacagataca tctctaaaat cagggaaatc agccaacaat agctttatta gtctctgcgc      7680
     ttgattatga cattttttga gtaatccgca gtatgagcca tgataagaat ctaccagtac      7740
     acggccagaa gctcgcatga ttcttatacg ctcctctaaa agcggtattt tttcaacggt      7800
     agcactgtca aatacagaag caatgagggt atcaggacat tgtttttcat cagcataaaa      7860
     agcagggctt gtaatgggaa taccagcatc taatgctttg ttaatggctg cacatagact      7920
     ccaataacca gtgtaaagct tccctttgta ttcaatagaa aatctcttgg aatgttttcc      7980
     actgtcttca acgtcaacgt ctgaccaaaa tgaaaaattc aaaatgtcca ccaagaaaat      8040
     cctaaagatt tgacgttaat acattatgaa cagggtaaac ttgttgaaat gaagtattaa      8100
     aaaaatataa agtgtatatg ttcagcagct catctttatt taatctacga aaacattcaa      8160
     gcgtccacac ataccaatct aaggtagaga cgtctcgggt tttagggtga agttcgtgat      8220
     tctgccactc agcgaattgg ggtcccaacg aatctagctt ctctttaatc catgttgcca      8280
     ctgctgcaca accaccttta ttaactttca catcgtttga gttctttcaa tcgttcatgt      8340
     tagcagttat taataagtag taaaattacc aaagaaataa attcagcatc ttgaagcact      8400
     cgggacatta taagagtttt aagggaacgt ggatgatgcc agtttacact gagacctaga      8460
     aaggtaaaac acaagaaaaa taagagcacg aacgaatatt ttgtaagaca agcgtactaa      8520
     ggattcatta aaaagtaatg aaggaggaaa gtgtaaataa gtatttcatt tcatacatgt      8580
     atctataaat tattcgtact ttatcttact ataattatat tattctatag atagcccaat      8640
     tttacaatcc aagaactact ggtttgtgta acacttgagc tattagcaac ctaaaaatgc      8700
     aaaggaaatg aatttgaacc gattaaattg aaactaggaa aaaaaacatc gatctttaat      8760
     tctacaacta tcaaattaaa tcaaccagtg aaaggacgaa ataattaaac aagcatgatg      8820
     actttagaag tatcattgaa tgtccagcgt tcatagatac ttaagaagac ttttcagttt      8880
     cgttttcgtt caattcagtg attgtagggc catcagactt agctgaagca ttgttagaat      8940
     tggacgaagt gccagtaaca gcagctgcag gcttgtttcc tcccccaaag agaccagcag      9000
     ggggagcaaa tggacgagat aagctacctt cagcagcctt attaaagatg taaatggaaa      9060
     ccaagttgtt agtaaacaag gaaatcaaag ggagaatgga ctgaatcacc aatggttgag      9120
     cataacccat atacaaatgc atgaacgcca tgatagctac acccatcatg gtagagcgtt      9180
     tagccttttg taattgctca ctatcatact ccttgacagt ggtggtcact agcttgccat      9240
     tgctttgtcc agaaaaagga ggtgcaggct cttcataaac caaaggagtc tcatcattgt      9300
     tggcattaat acgagcttgg ataattgcat agacaccaaa aataatggtg tttgagatca      9360
     cataggcagc acgagcataa tagacaattt gagggtcggt gaagtcaagc ttcttagaat      9420
     attgcataac acccaatgcg gcgacaagat ttaataccta aatttcgatt ttgtcagaaa      9480
     agctgaacat actttatatt tcttctatag tgcgaaatct aataaagccc atgcaaaaga      9540
     atacctcgca tttgacaaat attctcagaa cactaaagtt taaatataat aaaacttacc      9600
     tgagcgttca ttttcagaat tttagaaata aaaaagaata acttagctta caactgcctc      9660
     ttttttaggt aatggtggag gacaacttag ataatggcac tacaacaata atatgcgaag      9720
     ccatcaggtt taaggagatc tatcacagtc tcggtcatac cattcctgga acataggcga      9780
     aaacgtgaga aattaaatat aaacattaag aaatgtttag aaattttgga acattagtgt      9840
     tcctttatac tgtagagcaa atttgtttgt ttactaatga gatgattatt gtgttaatat      9900
     atttgtatat tgtaaattag tcattaatta aataataata attctttaaa gtaaggtgtt      9960
     cattatccaa gaagcagtta tagcaatcta aatggcatgt cagaattata cgaaaaagga     10020
     ttcaacttaa taatcctaaa agaggataaa ataccaggtt aatggacctg ttcagtttaa     10080
     aaacgaatag ttggtatata aaccaaatgg taatgatgat tgaataatga aaagttgata     10140
     ggaaacgtaa atgcagagta acatacaaaa caacggtgga gcttttgaca gacaaaactt     10200
     tttaaaggga agattcgtta taaaaaattg tttttcatgc agcagtaaga cctacactag     10260
     ataaagggtt aataaataag agcaaattaa tgttttccaa actccattac gtttaggtac     10320
     ttaccaaaaa tgatttacca tagcgcattc tcctcctgtt cgcaaattaa cacgaaaaga     10380
     ataaaggttt ccgtcataag ttgcaacatt tacaatagta ttatctggac cgaaagcagc     10440
     gattgaggtg accttatcac caggtatatg agcgtatgca aaatctcttt ctgggtcgag     10500
     cattccagaa accgactgcg gaaggtatcc accaacagta cctatgagtg atcttgagga     10560
     acgacgaagt aagctttctt tgggaggggg agaagaagga agaagacctt gacgctctaa     10620
     attagaatat acctccttga gacggaaaat gtgaacggtt tgtgtactag atgttaccgt     10680
     caaaagacta gaatcgggat gaaaagcaat agaataaatc tgggcaggga gagaaccacg     10740
     acgaaactga tataatcgct ggcctgaagg tatagcgaaa actcgaataa ttcgaccatt     10800
     atcagaagca gttgcaagca ttgtgccgtc agagttaaat gccaaacagg caagtgaatc     10860
     tttatgggct tcaattttgg ttatttgctt acaattgatt acatcccaca aaatgacttg     10920
     accagaaaca gcagaattag atacattagg actggaggac tcaccttccg tcctaggctc     10980
     atgatcccga ctatcaggat acgccaaata gcaattttcg gaattcggtg aaagagcaca     11040
     aacagctgtt acaataaaga attagtgata ttgtagttgc gaaaagacaa gtgtttttga     11100
     tgttgcttac cgaacacatt actagttgtt tcgattgtgt gaagcaaaag catattgctt     11160
     atatcatata cataaatttg ttcctccaaa accgccagca agcgttttcg attcagcttg     11220
     acagctagta aaggagtcgg aaatgtcaac tcacatattg tagtgctttt ctacactcgt     11280
     tagtagagag gaaataaaaa aaggggcaaa gcattagaca ttttgagctt acctttgtgt     11340
     taattaactt cagctttcta ttatttccat cgtccttctc cacaagagcc accagagatg     11400
     tactgaacag catctctact attgaagtag caccttgaac taaattaggt tagaaaaatg     11460
     tttcaatgat gatggttttt attacaaaac actttattac ctacttttgt gaaaacattt     11520
     tccaaacgga tcacaattgt atatcttata tccatcgaat gttccaatgg agagcaaact     11580
     acaagtatta gtgatgttga tatcaaaaac aataaaataa gtactttgaa tcctggttaa     11640
     atccacaaaa tagtaagcga gacatattcg ataccatttt cagcacaatt ggccgatacg     11700
     tatattgttc taatgactgg cttgagacaa gtggaatgac ccgcggctat acacttacat     11760
     acgctgcttt gccgcggtac ttccgaacaa agaaatgcat tttgaagtaa aacgaaaact     11820
     agttgtatac ttgaaaacaa gtgtaattgc tccaatgttt aaaattacaa atatagaatg     11880
     tgaacaaatt tcgacacttc aaataggttc aattagtgtt acatatttga ggtattgaaa     11940
     gagccactga agttgtaaat gtgagtatcg aaaatagact acaaatacat attcatttta     12000
     ttggaaattg aagattggag aagctattac atatgagttt actgaacgct ttctagaact     12060
     tttaaagcaa ttgtctacag ttcacttcgc tgaagaaaaa tgtgcattaa aatgttaaaa     12120
     attgtatata aatcgtaaaa ttgaatgatc attatgattc cgttgtttca ttatccaacc     12180
     tgatatgcta ggttattccc ttcgactatt ataataataa atgaaaaaga aaaaacttca     12240
     accagtctcc cttgcttaaa taaatttatc tggaagcgga ataggtttct ggccgttcaa     12300
     tgaaagaagt gtcatttgta gcaaatgttt cgtctgcagt tgcaaaattg ggatcgtgag     12360
     aaataacacc accatcgtag ggagggtcag aaatcgaatg accagtacga gtcatcagcg     12420
     ttgccttaaa ttggtctttc ttagcttgga gtaaaaaact ttccgaaagc ggtgcatttt     12480
     cataatctac gcaaaaagca ttgatttgca atccataaag aaaagaagaa aacgattcgt     12540
     tgaaattgtc gagtatttgt ttggttgctg acaggtgatt cattcgttta cgaaattcac     12600
     tcacattatc atccaaaaca gccagtgact tagtaaaggc ttggagattc gaagggattg     12660
     cattctcact ttctattttc acattatcaa cattttctaa aggattttga gtagctttct     12720
     ggtatttctc catgttttcg cgactttggg tgagatgtag atgttctaca gcgctttcgg     12780
     cagcagcagc aggaacattt ttcttccgac gttctcaaaa acagcctgag cctgagactg     12840
     tagacgaaaa agtgagcttt gaaagttatt cacctttaaa gttgatgatt caaaagacat     12900
     ggcctaggtt tcaagagcat aaagaatatc gcgaatcgtt catacgatta gcaaaatgcg     12960
     actcacccga cgctatctta gtacgatttt tggcttcttg caataacgat tcacatgaag     13020
     caagtcaaaa gttaatcaat acgctacaat ggcgcgtaga tacaggtgtt gagcgtatcg     13080
     ttgagcgggg tgagctttat gccaaagaga caaatgatga tcagttcttg gaacaattga     13140
     gaactggaaa ggtaactatg ttgggaaggg acttatctga tcgccctatc tgctatattc     13200
     aagtccattt acatcaaccc tcaaaattga ctcagaattc tcttcgtgag atgaccgtgt     13260
     gggtaatgga aactatgcga ctttttctgc gaccacaaaa gactttgaag gactctatgg     13320
     actctcctca aaatgtgaat gttctgttcg accttagtaa cttttctcta cataatatgg     13380
     attattcttt cgttaagtat ttggcatcgt gtttggagta ttattaccca caatctcttg     13440
     gtgtttgtat tcttcataaa tctccttgga ttttcagaag tgtttggaac attattaagg     13500
     gatggattaa accagagatt gctgcgaaaa ttgtttttac tcagagcgca aacgacctcg     13560
     aaaaatacat agactattcg gtaattccta cttctttagg aggaggcaac aaaaagatat     13620
     tccaatacat agagccagta gagcatgaga atgatgcagt catcgaagat agcgctgaaa     13680
     agactgcagc acttgctcgc tattatgcgt atttcagtga atgggagcag cactctttaa     13740
     attgggccaa gctagatgat gatgatgctc aaaatgaaaa agtccgctta tgctgcgatg     13800
     ctgcaggtac caactttgcc aactgctatt ggaatgttga caaatatata cgagcgagaa     13860
     ccgtttacga ccgactgaaa tggattggta atgtttaaat ttactcaatc taaacgctat     13920
     gttttacgac tcaattcttt ttattctttt attaataaaa gaatgcatct tcctatattt     13980
     actacctttt actaaaaact tgagtttaga tctaatgtcc tcgaaatact catgattcct     14040
     caatggcgtt ttcaataatc gcgtttgcgc atataaaaac tgttgaaaat tccaccaatc     14100
     attcaaccgt agcttgcttg tttagtttgg cttatgttta gattatttat ttaaaaaaat     14160
     catcatggga ctactagaaa tataatacaa atgaaatgtt ttcataacca tttacaatat     14220
     aagtattttc aattcaatat agcacattac aatgagcaat atagatatat tacaaaatat     14280
     cacttaaaaa agtgttaatt tattttatcg caaactcatt taagcttcca atttgagggt     14340
     caagtggcat ctaccacagt aaaggcggtc cttgtggttg gccatgaagg tggatgcacc     14400
     acagttagga cactcacgac gaagacgctt aacgcttcca tcatcctcaa ccttgtagta     14460
     cttgaggacg gcgagctcaa ccttcttgtg cttgtgcttg atcttcttgg gagtagtgta     14520
     agtcttcttt ttacgcttct taccaccacc acgaagacgc aaaacgaggt gaagagtgga     14580
     ctccttttgg atgttgtaat cagacaaagt acgtccatct tctaactgct taccagcgaa     14640
     aataagacgt tgttgatcag gaggaattcc ttctttgtct tggattttgc tcttgacatt     14700
     atcaatagtg tcagaggact ccacctcaag ggtaatcgtc ttacccgtaa gggttttgac     14760
     gaaaatttgc attttggttg tgcttagaaa tgtttttcga aattcatatt tcttttgtta     14820
     agttgtgact gcttactact gctgtacttg gtaaggtatg actctaaaat tttaagaata     14880
     agaagccgag cgagaattca atattctaat ttagcggtca aattttcaac tcgttaaacc     14940
     ataggtgcac taattgagca atgataaatg cacattagaa aaggaaagtt attgtctcag     15000
     ttggtgcagt aaactgatga atgaatttta tagatgaaat acaccgtaac cattaagttt     15060
     agaaaatgtt tgctaatttc cggaattgct tcaaaatcaa gaatagtcgt ttaatttatg     15120
     acaatatcaa taaatgtctt ctcactaaag aagaaactaa tcaattgtta aaattcattc     15180
     atttaaaatg gaaaccagct aaaggtatgt attcagtaga aacgccaagg tacttaaaag     15240
     gcttactgtc tttcgtttga aagatgaact tgcattattt cggcaaaata tatgcgttta     15300
     ccaatttctt atggttcata aataaattgt caatttcctt gcagttgtta ttcaaagtat     15360
     tcgacaaatc ttattcttgc atcaatcgat ttgaaggtta aagatacaac ggattgatgg     15420
     tataaattct ttgtgaaggc taagggaatt cttgatattt ttccaaacca gttttttcaa     15480
     atattaacta ttgatagatc aagtccaaat atcgttttca cgtagtagtg gtcctggagg     15540
     tcaaaatgtc aacaagctta atacaaaggt gatagtaaat cttccattca aacaattgga     15600
     aagttgtata cctatgtttt taattaatca ttttaaaacg tgtgagatgt tgagaaacta     15660
     ccgtatacaa aatggaataa agatctactc tcagaaaact cgttcacaac acaaaaacat     15720
     tgaagatgct ttaaacaaga tatctgattt attgaacaaa tcagccgaaa ccctctatgt     15780
     tccagatact cctcctgaaa aaatagcacg gattagtatc ttaaaaaaag aatcgaatga     15840
     aaaacgattg tcggaaaaga aatataaaca aaagaaaaaa acgcaacgtc gtatcactat     15900
     ggattaaaat aattcattga ttaatattgt gactcactac ttgctttgtt tatccattta     15960
     atttgctgac atttttcgca ccacttttcg aatgtaaact atgttatgac tcgctatggc     16020
     atacatatac aatcacatat taataacact tgaactgaac cacaccttag tgcaggagca     16080
     attttgcttc aaatgacaga aaaaacaagc tctttagtgt tttcagccca atacgtggct     16140
     ttggtgcata ccatatgctc ttttgcagcc ttttttattc ctctagcatt agcattatac     16200
     acacactatt atcaggtaaa taaaccacaa atacagtcag aataatttcc ttcttgagta     16260
     atatccaata gttactattg atccccagtt tattagcgct gcaaacagtt catcgattgc     16320
     ttgcatgttt gcaagcactg agccacaaga cagacgtgac attcgcaaag tttacaattt     16380
     actaacatta tatttgcagg tggtgaagaa cgaattttat ggatatcctg aagaatggtt     16440
     tccttcggtc tctgctacta ttggtgattg gtatccagaa aggtcggtat tccagtggct     16500
     tattgctcta acagcaacac ctcgtcttct tgttctgttg ctttggttta cattaagcgg     16560
     aatttcaaga ccatcagtaa ttattactac agcgttgggt gttttacgaa ctgctctctg     16620
     tggtggatgg gtttatgtaa cttcgactga tgaccatgat tggcatgata ttttcatgat     16680
     tggatattta atttctaacg ctccttggtt tattttggtt tcaaaatgtt caccagttaa     16740
     ttccatggct tcacgtatta gaaatattgg atcagcattg ttcgttttga ctatatttcc     16800
     cttaatttac tggtatattc agcacaagtt taaacatatt cctggtgcct atactgttta     16860
     tgcattcttt gaatggtcat tgatattgtg ggacatactt tttgattctg cgttgtactg     16920
     ggattttaaa ccactcgtgt ttaatctgca tacatcaaaa acctactcta atccatcttc     16980
     ttttgctaca cgcaagaagg agaaaggaga acatttgtct tatgcagagg ctgcagctgt     17040
     tggcacgcaa gcaaagaata tcaaaaaaga tagtaacgtc aagtgttcca aaaagcaaat     17100
     cttgtttagc ttgctatact tttcatctga ggtgtatctt tcttttgtct tctggagcgt     17160
     tcttactagc ttagggttat tagtatggta ttttccctta tggcatatgg ggatttcggg     17220
     ctatgaagcg tgcattcttt tcgaactttc tccattctta cttggtattc cactattgcg     17280
     aaaatttgcc tcaaaagtac ctgttatatt tttattttta aatgttatag gtatagctgc     17340
     ctataagctt gaggacccgg tgcacagatt atttgttact gcgttttctg tctgttgtga     17400
     atgtctcgcc tggacttctt tattttcaaa tatttcgcct gaaaatttag caatagaacg     17460
     taaaattagc acatttttgt ttggattgct tgcgtcttca atcgccaagt actctttttt     17520
     ttctaacaat cctatatggc ctattttaaa tgaaacaaac ggtggaaaac aaatcccagc     17580
     gttaattgtc ggaataattg catgtctaat atttgccatt ttccatgtgc agcaaacaac     17640
     agcgaatgcc gtggaacatt ttaaactaag gaagataact gctctgtctg cagccctaag     17700
     cttgggcaca gtactttttt gtctgcatac ttttctttgt gactctacag ttcttatgac     17760
     atggtcgtgg gatgggtatc ctattaaggg accgcaacct tatccacacg gtgccgtttc     17820
     aatagttgtt tccatttgcg ctgttttggt agccccttat ttatatcaat caggtgcttt     17880
     tatgcttatt ggatttgttt tagcctgctt cggatcatat tttatgtata ttaaccatgg     17940
     atggtgtagt tatttgggtg ggttaatatt tacttcctac gttttaattt actcgttcgc     18000
     ttctatcaga atttcctcct tctattctcc tgcgaaggtt tggggtggcg cttttttggt     18060
     ttacatcctt tactcattag ctcatgtttg ggtcgtagcc tacgagtttg ttccaggtgg     18120
     acccattctt cgagagagaa cttcttacat tctaattttc attggttgga accttgcagc     18180
     tttagtacct gcgtattcgg gtgagtccaa agaacccaac aaagcagact catctgtagt     18240
     agatatcaaa caatcagatt cttcttatcg tagaagaagt ttcaaaaaat cactattgac     18300
     aggtttttgt ctggctctta tggccctaaa atttgccatt ca                        18342
//