ID SPAC57A10 standard; DNA; FUN; 26600 BP. XX AC Z94864; XX SV Z94864.1 XX DT 28-APR-1997 (Rel. 51, Created) DT 19-DEC-2001 (Rel. 70, Last updated, Version 7) XX DE S.pombe chromosome I cosmid c57A10. XX KW beta-transducin; cdc17; cyclophilin-related; KW dihydroorotate dehydrogenase precursor; dnaligase; high mobility group; KW HMG_box; KW peptidyl-prolyl cis-trans isomerase nonhistone chromosomal protein; KW protein kinase; rna binding; serine/threonine-protein kinase; sla1; KW Trp-Asp repeat; ura3; WD domain, G-beta repeat; WD-repeat. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26600 RA Badcock K., Churcher C.M., Wood V., Barrell B.G., Rajandream M.A.; RT ; RL Submitted (21-APR-1997) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; P12000; P12000. DR GOA; P32747; P32747. DR GOA; P87049; P87049. DR GOA; P87050; P87050. DR GOA; P87051; P87051. DR GOA; P87055; P87055. DR GOA; P87056; P87056. DR GOA; P87057; P87057. DR GOA; P87058; P87058. DR SPTREMBL; P87056; P87056. DR SPTREMBL; P87057; P87057. DR SWISS-PROT; P12000; DNLI_SCHPO. DR SWISS-PROT; P32747; PYRD_SCHPO. DR SWISS-PROT; P87049; CGP1_SCHPO. DR SWISS-PROT; P87050; CDR2_SCHPO. DR SWISS-PROT; P87051; CYP2_SCHPO. DR SWISS-PROT; P87052; YDJ4_SCHPO. DR SWISS-PROT; P87053; POF1_SCHPO. DR SWISS-PROT; P87054; YDJ6_SCHPO. DR SWISS-PROT; P87055; YDJ7_SCHPO. DR SWISS-PROT; P87058; LAH1_SCHPO. DR SWISS-PROT; P87059; YDJB_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c57A10 overlapped at the 5' by cosmid SPAC19E9, CC EM:Z98975 and at the 3' end by cosmid SPAC20G8, EM:Z95334. XX FH Key Location/Qualifiers FH FT source 1..26600 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c57A10" FT /map="IL" FT misc_feature 1..202 FT /note="nominal overlap with cosmid SPAC19E9, EM:Z98975 S. FT pombe chromosome 1" FT CDS 1..939 FT /codon_start=1 FT /db_xref="GOA:P87049" FT /db_xref="SWISS-PROT:P87049" FT /note="SPAC57A10.01, len:312" FT /partial FT /gene="SPAC57A10.01" FT /gene="SPAC19E9.03" FT /gene="pas1" FT /product="Pcl-like cyclin" FT /protein_id="CAB08164.1" FT /translation="DRSFSNRAWSRLSGLPVDKLLVLEYMFYQCIDYRLVVPKHIFARW FT SLLVGECCAHATARYDSTDPNVASFGSVAQYWVSLFSNVQSSLDDLFSIACLTKIAHRR FT MNANAALKNQATRKPSSSPQTTQDSSPILTMAPSTPVSVGSTPPSTPSVLPIAKQLAPM FT NVCKAHIQASNQSRTLTTASPPEQIPLMEPQVYVNPQVLPGRLSSLSKPVSLPPTPSSP FT KVGVYRPMTSKSNGGVAYCYNAQKLNNATGPVTFNMPFASVLPLAVSVSCDLGTASAYV FT ASLPQPCSQKRHLEEDYSCLTEHSAKRRSYF" FT CDS 1979..4306 FT /db_xref="GOA:P87050" FT /db_xref="SWISS-PROT:P87050" FT /note="SPAC57A10.02, len:775" FT /gene="SPAC57A10.02" FT /gene="cdr2" FT /product="serine/threonine protein kinase; regulation of FT cell cycle progression; nim1 family" FT /protein_id="CAB08165.1" FT /translation="MSTISEVGPWELGLSLGSGGPNSSRLAKHRETGQLAVVKPIVGWS FT ELTSSQQARIEGELVLLRLIEHPNVLQLIDVISAQEQLFVVVEYMPGGELFDCMLRKGS FT FTEQDTAKFLWQILCGLEYCHKLHICHRDLKPENLYLDAHGSIKIGEFGMASIQQPGKL FT LQTSCGSPHYASPEIIMGRSYDGCASDIWSCGIIFFALLTGKLPFDDDNIRSLLLKVCQ FT GQFEMPSNISPQAQHLLYRMLDVDSSTRITMEQIREHPFLSCFVHPNISIPIISAPIQP FT IDPLIVQHLSLVFRCSDDPMPLYEKLASQSPLVEKTLYTLLSRHLHPPSSAAVDRNRAV FT VDDLLGTAASNGQQMDEEEIEQAINIPTLAPYPISYAAESVPRPATSASPFLTPVTTSG FT TFNYSFNATNPQSILQRPATTSSAVPQLPKSVTPGLAYPHDSSMLSSNYRPPSALSPRN FT FNVSINDPEVQLSRRATSLDMSNDFRMNENDPSIVGNLAASNFPTGMGPPRKRVTSRMS FT EHTGNRVVSFPRGSAFNPRVTRFNVGNEQFSNNIDNNNYNQPYANATMNNSRRLRTPSG FT ERSMRADLSQSPASYDSLNVPKHRRRQSLFSPSSTKKKLSGSPFQPKRSFLRRLFSSEP FT SCKCVYASLVASELEHEILEVLRRWQLLGIGIADIIYDSVSASISARIKRQNSLNLKPV FT RFRISVLAEFFGSQAVFVLESGSSTTFDHLATEFQLIFEDKGFLDNLELSYFQASASRP FT VSRMSVSSSPFAVFRQRQSVQS" FT misc_feature 2006..2764 FT /note="Pfam match to entry pkinase PF00069, Eukaryotic prot FT ein kinase domain" FT misc_feature 2363..2401 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT CDS join(5344..5373,5414..5455,5521..5574,5779..5858, FT 5941..6037,6078..6242) FT /db_xref="GOA:P87051" FT /db_xref="SWISS-PROT:P87051" FT /note="SPAC57A10.03, len:155, SIMILARITY:Homo sapiens, FT Q9Y3C6, cgi-124 protein, (166 aa), fasta scores: opt: 732, FT E():0, (67.3% identity in 150 aa)" FT /gene="SPAC57A10.03" FT /gene="cyp1" FT /product="cyclophilin-1; peptidyl-prolyl cis-trans FT isomerase" FT /protein_id="CAB08166.1" FT /translation="MANVELQTSLGKILIELYTEHAPKTCQNFYTLAKEGYYDGVIFHR FT VIPDFVIQGGDPTGTGRGGTSIYGDKFDDEIHSDLHHTGAGILSMANAGPNTNSSQFFI FT TLAPTPWLDGKHTIFGRVVSGLSVCKRMGLIRTDSSDRPIEPLKIIKAVAL" FT misc_feature 5374..5379 FT /note="gtaaga, splice donor sequence" FT misc_feature 5400..5413 FT /note="ttaacattttttag, splice branch and acceptor" FT misc_feature 5456..5461 FT /note="gtacgc, splice donor sequence" FT misc_feature 5510..5520 FT /note="ctaacttatag, splice branch and acceptor" FT misc_feature 5575..5580 FT /note="gtaagt, splice donor sequence" FT misc_feature 5766..5778 FT /note="ctaattaaattag, splice branch and acceptor" FT misc_feature join(5779..5858,5941..6037,6078..6239) FT /note="Match to PF00160 pro_isomerase, Cyclophilin type FT peptidyl-prolyl cis-trans isomerase Score 156.06" FT misc_feature 5859..5864 FT /note="gtaggc, splice donor sequence" FT misc_feature 5929..5940 FT /note="ttaattgattag, splice branch and acceptor" FT misc_feature 6038..6043 FT /note="gtatga, splice donor sequence" FT misc_feature 6064..6077 FT /note="ttaaccatcttcag, splice branch and acceptor" FT CDS join(7330..7527,7591..8409) FT /db_xref="SWISS-PROT:P87052" FT /note="SPAC57A10.04, len:338" FT /gene="SPAC57A10.04" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAB08167.2" FT /translation="MPIIRSLTRGKSIRLLQKQSTKRTNPCVYLEAKAVEQTPATEFNS FT ILQEIISTEYNYSVDLKKTLNEIIMPIEGQSMEREAIGICTCFKTLNQLHTKLYQQMIS FT SGSPVYSLSQSLPAFRDVYHMYTINLSGISAIEKIISDPSSCNSQLLIPLQHLLRYPIH FT LARVCKMLRKYPFLNGDFRMAVKTLDDFRELCSYIDQEKAREESYQVLSALCGNQGVAV FT DIPRHIKFKGSVIPATSFIYDFNACVFCDDGLVVWTRYVKKIEMKAVSIEQCLRVDELS FT NSILVCTLNMKGKLLNRHLAPQTMAASVFLKWYHERAGISNGKENKLNRLKVVNAKT" FT misc_feature 7528..7533 FT /note="gtaacg, splice donor sequence" FT misc_feature 7579..7590 FT /note="cttacattttag, splice branch and acceptor" FT CDS complement(10199..12016) FT /db_xref="SWISS-PROT:P87053" FT /note="SPAC57A10.05c, len:605" FT /gene="SPAC57A10.05c" FT /gene="pof1" FT /product="F-box protein" FT /protein_id="CAB08168.1" FT /translation="MTTGYESVPTSEPSDNLAPRAELWQRHLLEKKEGDQSISVSAFNI FT SSMHNELSGLSEKSRQRVEAVWAAFSEASCSERKLALQGILNNCSSSLLSFASSTLDSL FT VRLDFLSLLPVEISFRILSFLDARSLCQAAQVSKHWKELADDDVIWHRMCEQHINRKCE FT KCGWGLPLLERNTLYAAKASIQKRYERLTKRGVDQAHESSPVKKAKLDDYPTSSNEETI FT SSVKPPSPNSDSKFFLPFKTRPWKEVYAERCRVECNWRHGRCRQVVLSGHSDGVMCLQL FT VRNILASGSYDATIRLWNLATFQQVALLEGHSSGVTCLQFDQCKLISGSMDKTIRIWNY FT RTSECISILHGHTDSVLCLTFDSTLLVSGSADCTVKLWHFSGGKRITLRGHTGPVNSVR FT IIRDRGLVLSGSDDSTIKIWSLETNTCLHTFSAHIGPVQSLALADSRLFSCSLDGTIKQ FT WDIEKKKCVHTLFGHIEGVWEIAADHLRLISGAHDGVVKVWEACECVHTLKNHSEPVTS FT VALGDCEVVSGSEDGKIYLWLFNNAPNESPVSTQSVPISSLNGQRSNSSVQRALSSVPN FT YSSSLSNISTRNLNIPPSNANNDDVSIQS" FT misc_feature complement(10406..10513) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 28.29" FT misc_feature complement(10520..10627) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 26.37" FT misc_feature complement(10637..10744) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 34.80" FT misc_feature complement(10757..10873) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 44.81" FT misc_feature complement(10883..10987) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 35.32" FT misc_feature complement(11000..11107) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 42.99" FT misc_feature complement(11117..11161) FT /note="PS00678 Beta-transducin family Trp-Asp repeats signa FT ture" FT misc_feature complement(11120..11227) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 44.37" FT misc_feature complement(11558..11695) FT /note="Match to PF00646 F-box, F-box domain. Score 50.36" FT CDS join(13720..14080,14165..14205) FT /db_xref="SWISS-PROT:P87054" FT /note="SPAC57A10.06, len:133" FT /gene="SPAC57A10.06" FT /product="hypothetical protein; sequence orphan; has FT transcript on microarray" FT /protein_id="CAB08169.2" FT /translation="MNVGDLKSANDLYESVRSIEGVTGVHLFRIRDAGILKSTMIPELD FT ALTTISLDELNKSPTVFTKNLLQGCGGTDLDVPAELKRLVIFVCNILESCNEFTDLGSA FT RLLRLTFDSCQLVIMYDSLFVVAITKDET" FT misc_feature 14081..14086 FT /note="gtatgc, splice donor sequence" FT misc_feature 14148..14164 FT /note="ttaactagaaaatttag, splice branch and acceptor" FT CDS 14438..15373 FT /db_xref="GOA:P87055" FT /db_xref="SWISS-PROT:P87055" FT /note="SPAC57A10.07, len:311, SIMILARITY:Saccharomyces FT cerevisiae, Q08634, chromosome xv reading frame orf FT yor238w., (306 aa), fasta scores: opt: 283, E():4e-12, FT (33.3% identity in 294 aa)" FT /gene="SPAC57A10.07" FT /product="hypothetical protein; similar to S. cerevisiae FT YOR238W; contains Pfam-B_32809" FT /protein_id="CAB08170.1" FT /translation="MLNKRLTIQLPFYATQTASSSRFWRVLSPKSRTGIALYASLILLC FT IFFTIFSTMSHPSLQCFSPTSLVGAQPLKNLTHLIIVAGHAVWLGGSTNGEDDSEWILE FT PYQKGEGKVFAQHVRSGLDLLSQDDSSLLVFSGGQTRNGAGPSSEAQSYYSLSMQINSD FT EGLAARRTTEEFARDSLENVLFSVARFYEVTSRYPQKITVVSFDFKRDRFLNLHRKAIK FT FPEHKFHFVGIDPEGGVSDATREAERKNAIIPFTEDPYACSNPLLVKKRMERNPFRRQH FT SYLITCPELIPLLQYCPSDPSKFFNGKLPW" FT CDS join(complement(15956..16879),complement(15796..15906), FT complement(15694..15753)) FT /db_xref="GOA:P87056" FT /db_xref="SPTREMBL:P87056" FT /note="SPAC57A10.08c, len:364, NOTE: C-term exons may not FT be real, LOW SIMILARITY:Mycoplasma pneumoniae., ESL2_MYCPN, FT putative esterase/lipase 2, (268 aa), fasta scores: opt: FT 169, E():0.00031, (27.0% identity in 267 aa)" FT /gene="SPAC57A10.08c" FT /product="putative/esterase lipase" FT /protein_id="CAB08171.2" FT /translation="MYFFTISRLTSFISYGILGALGILTFLYLYDAYLAKSFQRLVIER FT RSKRESLSKNLSPNDNSHNSKIDISSDYQLLNEYKVAYYLRPGIIPLNHNLAKQEVFVF FT LHGLGGQMSQFQKVMSYFPPTACLFSFDYWGCGLSRQAFPNQRIGSVDQLTTKGLSKLT FT YKVLEKLFPENTQFILIGHSMGATIASRVSKMLQTRCTALLLLNPKIRFTSKEISMIVR FT LRKTPNAFISLYRLLDRFHGLRSSSVTRSLSKNIKGDGDAVRAQLWLWNRQSNTKIWKT FT MLMGLEELLEPGFHFPKCPILILFGEFDPVSSLKDKVFFQDYPGNYTFKEIDTGHCSML FT EQPSEVYNCIDSFLDKFSTTDHNI" FT misc_feature complement(15907..15922) FT /note="ctgacttttatcatag, splice branch and acceptor" FT misc_feature complement(15950..15955) FT /note="gtacgt, splice donor sequence" FT CDS join(complement(18540..18669),complement(18401..18459), FT complement(17971..18108)) FT /db_xref="GOA:P87057" FT /db_xref="SPTREMBL:P87057" FT /note="SPAC57A10.09c, len:108, SIMILARITY:Saccharomyces FT cerevisiae, NHPB_YEAST, nonhistone chromosomal protein 6b., FT (99 aa), fasta scores: opt: 354, E():3.2e-17, (54.0% FT identity in 87 aa)" FT /gene="SPAC57A10.09c" FT /product="nonhistone chromosomal protein; contains HMG box; FT involved in establishment or maintenence of chromatin FT architecture; involved in transcriptional regulation from FT PolII promoter;FT similar to S. FT cerevisiae NHP6B" FT /protein_id="CAB08172.1" FT /translation="MPRAAKSSRKKDPNTPKRNMSAFMFFSIENREKMKTDNPDATFGQ FT LGSLLGKRWKELTSTEREPYEEKARQDKERYERERKEYDTKLANGEKTGKASAPAAAAA FT AKEE" FT misc_feature join(complement(18540..18624),complement(18401..18459), FT complement(18049..18108)) FT /note="Match to PF00505 HMG_box, HMG (high mobility group) FT box Score 61.38" FT misc_feature complement(18109..18123) FT /note="ctaacccaattttag, splice branch and acceptor" FT intron complement(18109..18400) FT /note="confirmed intron" FT misc_feature complement(18395..18400) FT /note="gtaaga, splice donor and acceptor" FT misc_feature complement(18460..18472) FT /note="ctaacgcgttag, splice branch and acceptor" FT intron complement(18460..18539) FT /note="confirmed intron" FT misc_feature complement(18534..18539) FT /note="gtatgt, splice donor sequence" FT CDS join(complement(20433..20646),complement(19675..20357)) FT /db_xref="GOA:P87058" FT /db_xref="SWISS-PROT:P87058" FT /note="SPAC57A10.10c, len:299aa" FT /gene="sla1" FT /gene="SPAC57A10.10c" FT /product="la protein homolog; RNA binding protein; similar FT to S. cerevisiae LHP1" FT /protein_id="CAB08173.1" FT /translation="MSTEEQKEEIKDISSKQENSSEVPKAEEAGKVVESQKDTTSEEKK FT EETTEKKEDDGKKDLSFDEAEVLKQVEFYFSDTNLPHDKFLWTTSQKNDGWVPIQTIAN FT FKRMRRFQPLEAIVNALRKSPELLEVDEAGEKVRRMIPLVRVDNKSVMERSVYCKGFGD FT EKDDTQIALEKFFEENAGPISAVRMRRDDDKKFKGSVFVEFKEPDVANKFLEKVKTAPL FT KWGEDELTIMSKKEYVDMKAELHKNDPPKFSSKRRRFDAFKEMDRQRPGKYSNRGRKFK FT KQRSSNASEEKPSAASE" FT misc_feature complement(19903..20061) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 39.24" FT misc_feature complement(20358..20373) FT /note="ctaacagtatgaatag, splice branch and acceptor" FT intron complement(20358..20432) FT /note="confirmed intron" FT misc_feature complement(20427..20432) FT /note="gtatgt, splice donor sequence" FT CDS join(complement(21925..22219),complement(21210..21856)) FT /db_xref="SWISS-PROT:P87059" FT /note="SPAC57A10.11c, len:313, SIMILARITY:Saccharomyces FT cerevisiae, YKT5_YEAST, hypothetical 47.4 kD protein in FT pas1-mst1 intergenic region., (427 aa), fasta scores: opt: FT 531, E():4.2e-24, (38.7% identity in 238 aa)" FT /gene="SPAC57A10.11c" FT /product="hypothetical protein" FT /protein_id="CAB08174.1" FT /translation="MFAKNLLFRFPKCIRINGYNNMRRSLLQRNGFQAGICRKFGTATK FT TDVWKGRFLPIVSGVAAASLTAGYLLGKNTSNASSSQDNDHPVVGEHVHTETQSYNEPY FT MQRHRIEDAIEKKMTSETQPSTDEKGRKVSATENSAPKKTDKEKSSGETAGNILREQIA FT TGKDDDEYARKFEEVEEESSEESAFNPDTGEINWDCPCLGGMAHGPCGEEFKAAFSCFV FT YSKSEPKGMECLDKFQAMQACFQKHPEIYQDMVGESEEEDAETNEKPSTTSDENNQPQS FT PPSDNASNPEEDVMNMEKEIVNLTPMSVIKEI" FT misc_feature complement(21857..21868) FT /note="ctaacaatatag, splice branch and acceptor sequence" FT misc_feature complement(21919..21924) FT /note="gtaagt, splice donor sequence" FT CDS complement(22643..23974) FT /db_xref="GOA:P32747" FT /db_xref="SWISS-PROT:P32747" FT /note="SPAC57A10.12c, len:443" FT /gene="ura3" FT /gene="SPAC57A10.12c" FT /product="dihydroorotate dehydrogenase" FT /protein_id="CAB08175.1" FT /translation="MYQRSLFRGVAQGLKRSSVRFQSTSSGSSNGNFFLRHWKLLSVIG FT SFTAGVAIYDMSDVRSFIHGRIEMPLFHAFTTPEFSHRVAILAASWGITPKDRVADDPS FT LAVEVWGKKFCNPIGLAAGFDKQADAISGLLNFGFSYLEIGSVTPKPQPGNPKPRYFRL FT KPDLSVINRYGFNSIGHDAILAKIQKRVRKYIAKTSPQLLKQFDANPASCTDPAVLGVP FT RSLIPNKFLGINLGKNKNGNEIEDYVEGVRTFGNFADILVINVSSPNTPGLRNLQKKSA FT LSTLLTAVVSERNKLNSPHPPVLVKIAPDLNEEELTDIADVLKKCKIDGVIVGNTTVQR FT PKTLKSTSHVEETGGLSGPPLKPIALNTLRTLRKHLSSDIPIIGCGGISSGKDAIEYAR FT AGATMVQVYTALGYDGPVIAHKIKQEILAELKGKRWVDIIGKEE" FT misc_feature complement(22715..23659) FT /note="Match to PF01180 DHOdehase, Dihydroorotate FT dehydrogenase Score 579.96" FT misc_feature complement(22769..22831) FT /note="PS00912 Dihydroorotate dehydrogenase signature 2" FT misc_feature complement(23495..23539) FT /note="PS00911 Dihydroorotate dehydrogenase signature 1" FT CDS join(25077..25159,25200..25707,25770..26600) FT /db_xref="GOA:P12000" FT /db_xref="SWISS-PROT:P12000" FT /note="SPAC57A10.13, len:473" FT /partial FT /gene="cdc17" FT /gene="SPAC57A10.13c" FT /gene="SPAC20G8.01" FT /product="DNA ligase; DNA replication" FT /protein_id="CAB08176.1" FT /translation="MRTVFSQIPRFKQVNQYIRMSTRQSDISNFFISSASHKSEHVEVS FT QSSSDSKNVDGRSTSEKRKVESVKLVDESKHNNHDDTGTQNVERENNIVSEAKKQKTLG FT SSSSSSDAVSSNNDSGASTPIPLPIKEPPLESNARNDKLKGHATFAEMVKAFTKIENTS FT KRLEIIDIMGTYFFGILRDHPSDLLACVYLSINKLGPDYSGLELGIGESIIMKAIGEST FT GQTLQQIKLSFHKVGDLGLVAQTSRQNQPTMFKPAALTIPFLFDSLKKIAQMSGNQSQN FT RKIGVIKRLLSSCEGAEPKYLIRALEGKLRLQLAEKTILVALANATAQYHADKNGEKLS FT QQDRIEGEQILRDVYCQLPSYDLIVPHLIEHGLGTLRETCKLTPGIPTKPMLAKPTKQI FT SEVLNTFDQAAFTCEYKYDGERAQVHFTEDGKFYVFSRNSENMSVRYPDISVSVSKWKK FT PDARSFILDCEAVGWD" FT misc_feature 25160..25165 FT /note="gtttgt, splice donor sequence" FT misc_feature 25187..25199 FT /note="ctaacccatatag, splice branch and acceptor" FT misc_feature 25708..25713 FT /note="gtatga, splice donor sequence" FT misc_feature 25748..25769 FT /note="ctaacgtctttttttacattag, splice branch and acceptor" FT misc_feature 26397..26600 FT /note="nominal overlap with cosmid SPAC20G8, EM:Z95334 S. FT pombe chromosome 1" XX SQ Sequence 26600 BP; 8520 A; 4786 C; 4714 G; 8580 T; 0 other; gatcgtagtt ttagcaatcg tgcttggtct cgcctatcag gacttccagt tgacaaatta 60 cttgttttgg aatatatgtt ttaccaatgc atcgattatc gtcttgtcgt tcctaaacat 120 atttttgcta gatggtctct tttagttggt gaatgttgtg ctcacgcgac tgcacgttat 180 gattccaccg atcctaatgt tgcctcattt ggcagcgtcg cacaatattg ggtctctttg 240 ttttctaatg ttcaatcttc tctagatgat cttttttcca ttgcctgttt aacgaagata 300 gcacatcgca gaatgaatgc taatgctgct ttgaagaatc aggctacgag gaagccctcc 360 tcttctcctc aaacaactca agactcatca cctattctta cgatggcacc ttctactcca 420 gtatctgttg gcagtacccc tccatccact ccatctgttt tacccattgc caaacaactg 480 gctcctatga atgtctgtaa agcacatatt caggcttcaa atcagtcccg cactttgact 540 actgcttcgc cacccgaaca aataccgctt atggaaccgc aagtttatgt aaatcctcaa 600 gtattaccgg gtcggttgtc aagcctttct aagccagtta gtctaccacc aactccttct 660 tcaccaaagg ttggagtata tcggccaatg acttctaagt ccaatggagg tgttgcttac 720 tgctataatg ctcaaaaatt gaacaatgct actggtccag ttacatttaa tatgcctttt 780 gcaagcgtct taccacttgc cgtatctgtg agttgtgatc tgggtacagc gtctgcatat 840 gtcgcgtccc tccctcaacc ttgttctcaa aaaaggcatt tagaagaaga ctactcatgt 900 ttaacggaac acagtgctaa gcgtcgcagt tacttttaat tatcaagccc aatctgcgct 960 gtcttcgccg cttctttcaa aaactataat atttaatgaa taatttcata atactgatgc 1020 cattttaaca gcggatgtca ataaataccg ataatgtttt ctttctattg atttatctat 1080 tcaaattgtg tggaagataa tcatgatatg ggaaacttga ttaggtttat attactacct 1140 tcttttcata tctagacttg tcaatgtttt gattaaaaat caaatattgt tgtcgtttct 1200 atgaatcttt ttttaacatt ctaatagcaa aacgatgtat atatggtatg aatgaattaa 1260 cgattggcaa ctatatttac ttatgcatct tgtaaattga tatcagtaga gcaaggtatt 1320 caaaaaagat aattttgttg atttcttatg gccataaact tgtcaaatag tcaaactatt 1380 tagagattat gtatgtgctc attaagatag ttatatattt taggcaggtg aatgtagcca 1440 tttgaaatct actactgagc tccaatccta tttgaaggct ctaagagtcc tttcaatcat 1500 tttttaacag agttgtctaa gtaatatttt ttcaacgatt aaactgtgaa acattgaact 1560 aaaatatctt gatcatttac aaaagcagta attgctacac cgtactacta gtagagccaa 1620 ttttgattac ggtctttaaa acaatgttga atacactaat tgtaagcgat ttttgtaaaa 1680 actaataatt atacgtatct tcttgaacat cacgaaaatt aactgatatt tccctaaagt 1740 acagttgcaa gtaggaagga ttaagacaaa acaacaaatt atatactaaa aattttacaa 1800 atgttaaaat caatttcaca tatatatttt gttgtaatta aatgcactca aatactatag 1860 cttacaagtt tagggagcat tacggagaac atcccacata tgctgttcta tgaatggggt 1920 ttggatttgg ccatcaccac ttcaccgatt tactggttct tttgaatagt tgaagtgtat 1980 gagtacaatt tcagaagttg gaccttggga gcttggtctt tccttaggat caggaggacc 2040 aaattcatca cgtttagcca aacatcgtga aactgggcaa ttagccgtag taaaaccgat 2100 tgtaggatgg tccgagctta cttcgagcca acaggctagg atagagggtg aattagtttt 2160 gcttcgattg atcgagcatc ctaatgtttt gcagctcata gatgtgattt cagcccagga 2220 gcaactcttt gtcgtagtcg aatatatgcc aggtggtgag ctttttgact gcatgcttcg 2280 taaaggaagt tttactgagc aagatacggc aaagtttcta tggcagattt tgtgtggatt 2340 ggagtattgt cataaacttc atatctgcca ccgggattta aagccagaga acttatactt 2400 ggatgcccat ggttctatca aaatcggtga attcggtatg gcgtctattc aacagccagg 2460 aaagcttttg cagacttcct gcgggtctcc ccattacgca tccccagaaa ttattatggg 2520 gcgttcatat gatggttgtg ctagcgatat ttggtcatgt ggaattatat tttttgcttt 2580 gttaacaggg aaattaccgt ttgatgatga caacattcgt tctttgttgc taaaagtctg 2640 tcagggtcaa tttgaaatgc catcaaatat ctctcctcaa gcccaacatc tgttgtaccg 2700 catgcttgat gttgattcat ctactcgaat taccatggaa caaattcgtg aacacccgtt 2760 tcttagttgc tttgttcatc ccaatatttc tattccaatc atatcagccc ctatacaacc 2820 cattgatcca ttaatagtgc agcatctctc tttagttttc agatgttccg atgatcctat 2880 gcccttgtat gaaaaattgg catctcaatc acccttggtt gaaaaaactc tatatactct 2940 actgagcaga cacttgcatc cgccttccag cgctgcagtt gatcgcaacc gcgctgtggt 3000 cgatgatctc cttggtacag cagcatccaa cgggcagcaa atggacgagg aagaaattga 3060 acaagctatc aatattccta ctttagcgcc ttatccaatt tcttatgctg cagagtctgt 3120 tcctcgacct gctacttctg catcgccatt tcttacacct gttaccactt ctggcacttt 3180 taattactct tttaatgcta ccaaccccca atccatactt caacgaccag ccactacatc 3240 ttctgctgtt cctcaactcc caaaatcagt taccccagga cttgcatatc cccacgatag 3300 ttcaatgctg tcatcaaatt accgacctcc ttctgcatta tctcctcgca actttaacgt 3360 ttctataaac gatccggaag ttcaactaag tcgtcgcgct acttcactgg atatgtcaaa 3420 tgattttcgt atgaatgaga atgaccctag tattgttggt aatttagcag cttccaattt 3480 cccgacaggt atgggacctc caagaaagcg tgtcacttct agaatgtccg aacacactgg 3540 taatcgagtc gtaagcttcc cgcgcggcag tgcttttaat ccaagagtta ctcgcttcaa 3600 cgtaggaaat gaacaattct ctaataatat tgataataat aactataatc aaccatacgc 3660 aaatgcaacc atgaacaact ctcgtcgtct tcgtacccct agtggggaga gatcaatgcg 3720 tgctgatctc tctcaatcac cagcctctta tgattcgttg aatgttccca aacatagaag 3780 aagacaatcg ttattctctc cttcttctac aaagaaaaag ctttccggct caccttttca 3840 accaaaacga tcatttttaa ggagattatt tagtagtgag ccttcttgta aatgcgtcta 3900 tgccagcttg gttgcttcag aattggaaca tgaaatttta gaagttctta gaagatggca 3960 gcttcttggt atcggcattg ctgatattat atatgattct gtgagtgctt cgatatctgc 4020 tcgtattaaa cgacaaaatt cacttaatct taaaccggtt cggtttagaa tatcggtact 4080 ggctgagttt tttggttcac aagctgtctt tgtgttggaa agcggttctt ctacaacttt 4140 tgaccatttg gctacagaat tccagctgat ttttgaagat aaggggtttt tggataattt 4200 ggaactctct tattttcaag cttcggcatc cagacctgtt tctcgaatga gtgtaagtag 4260 tagtcctttt gctgtatttc gtcaacgaca atccgtccaa agttaaattc ttttattatt 4320 attattatca tttttttttg attctccaaa acctttgcaa acttcatttt tctcgtgatg 4380 ctttggaaaa aaaaggatta tcaaaaaagc taatcgtttg ataattgaac ataatgtata 4440 ctcgtggaag tattggaact ttttgaatta agctttcatt ttgtcccata ttggaactct 4500 ttttatacac caacaatatc tttatagacc tccattcttt ttctgatgtt tttcttttac 4560 ttgttcaact tgctatatgg aaccacggtt atccgggaag caataaatgc atttaatgat 4620 taaattatat tttgctgctc tgctacaatg tttctcttgg aacctgttga gttttgtaca 4680 tgtgatgttg tacttggaac ttactccaat gataataact tgcatgtctg aagcaaggta 4740 atttttgtat ttagtatgac cggctattgc tggcatcttt tttgaaatac atttttctta 4800 tttaatttag gtataaaatt ttttatctta atcaatcttt tcttttggct ttctaactct 4860 tcgttctaaa tcacaatctt tttagtctcg tttatttcaa tcgatttgac tttttcttca 4920 tcttatttat cacaatcaac tagcactagc ggatacaatt tcaatgaact gcagcatagg 4980 tcgtattatg tttagaaatt tatgaccctt ctgcttgttc tgtataaatt aaatttattc 5040 caattaagta tttggtcgct caatgctaat tagtatgata ttaaatttga gtggaattca 5100 atatgtaacc tgcttacttc gatagttgaa gaaatacatt tgaagttgta ggatatctag 5160 gttatctgca ttgtacaaag agtctgtttt tttggaatga agtacgtgac atattattaa 5220 gcacttttaa aattgtctgt gcaattgcct tttcagtatt tttagcgagg ttgcaacttc 5280 aacttattac ttgaacaagc agcgaaaaac tgcaagaaaa tcgtgtaaaa actagtaaat 5340 accatggcta atgtagagtt acaaacaagt ttggtaagat cttttccaag ctcaagcatt 5400 taacattttt tagggaaaaa ttcttattga attgtataca gaacatgctc ctaaagtacg 5460 catcaagaat aaaggacgaa cagtgttgtt tgctttgaaa gtagaatcgc taacttatag 5520 acatgtcaaa atttctatac tttagcaaaa gaaggatact atgatggtgt tattgtaagt 5580 ttttttcgca ctgtttgcat cgtgcaaata agcatgttga aatatgagtc tacaatttaa 5640 tatttcaagt gtgttatttt attgatttaa ctgttcacat ttacatgatg gactcagtca 5700 gtcatataaa tatgtgtcct ataattcatt caatatcgta tttgatttaa ttcgtgaaat 5760 tggtactaat taaattagtt tcacagagtt attccagact ttgtaattca aggaggggat 5820 cccacaggta caggtcgagg tggaacttct atatatgggt aggcaaagct ttataaatcg 5880 gcattcaccg attgtttgca tctttattac gaagttttca cattcttatt aattgattag 5940 ggataaattt gacgatgaga ttcattccga tttacatcac actggagctg gcattttatc 6000 aatggccaat gctggaccta acacaaattc atcacaggta tgatgacttt gtttacacta 6060 actttaacca tcttcagttt tttatcactc tagcacctac tccttggtta gacggaaaac 6120 atacaatttt tggtcgtgtt gttagcgggc tttctgtgtg caagcgtatg ggtcttatcc 6180 gaacggattc atctgaccgc ccaattgaac ctttaaaaat cattaaagct gttgcacttt 6240 aaattattct ttaaaggata ttcaaaggtt ttaatctata agtctttttt cgatttttca 6300 acacatcctg aagatattga ctaaagttat ttgtcacgga tattaaaagc taaattaata 6360 gttgataaag agaagcattt ccttacaaaa ggtggacttt ttaattgaag tcaaatttta 6420 caagtcaagt ggaataacat aagcttctaa gaaggaatta actagttttc tagcttaaga 6480 aattggagat ggattttgtt acgcatatca acctagttgt ttgaccataa acgattgaac 6540 aaaaaccttt tacaacgtta gcattgcttc cggtactttt ctccttatca aaaattttac 6600 aattgtattt ttttcttaat tagaagatta aagctcgggc caaatataca actacaagag 6660 tttattggac tagattactc aaatactatt gcttcagttt ttttgttaca acgtgggatg 6720 ttattttaaa aaaaattcag aatcaaaata aagtccaatg cataaaaacg gcatgaatcc 6780 ttctcttttt tatttaattc ttcttttaat tgtttacgcc aatttgtgtg atccataatt 6840 agcaaattat tttacgtgtt ttaacgtatt acgttataat tgtaattaag caaataaatg 6900 atatttgtca attgaaggtt cgaatgtagt ggtcacggaa tactcacaag catgataata 6960 atgtttttta aggtcctaat atatctaatt gacctttcac agctagacat atcaacatat 7020 gaccaaaact tagcttcatt cctcaagcgg gaaacattca ttaactgaaa ttgtccatga 7080 gaaagacttt ttctattgaa agataagttt gaaaaggcta caaactttaa atacttttaa 7140 taaagtaatt ttattaacta actattcctt tgcttactta tagatttaag atactaagcc 7200 acagttacgc aaaattggat aatgaacttt agtgacatag gttttacact gagtagttga 7260 ctttggagcg tgttatttac atgcaatttc ctaacacgtt tcgcctggag catggcactt 7320 ttaaaaacga tgccaatcat aaggtctcta acgcgtggaa aatcgattag attacttcaa 7380 aaacaatcaa cgaaaagaac taatccgtgc gtctatttag aagcaaaagc tgttgaacaa 7440 acaccggcta ctgagtttaa cagtatactt caggaaataa tttcgacaga atacaattac 7500 tctgttgatt taaagaaaac attaaatgta acgattacta tagcaaatat tatgctcgtg 7560 tttactagtt tgtgattact tacattttag gaaattataa tgccaatcga aggccaaagt 7620 atggaaaggg aggcgattgg aatttgcacg tgctttaaga ctttaaatca gttacacacg 7680 aagttatatc aacaaatgat ttccagtggc tctccagtat attcattgtc gcaatcttta 7740 cccgcttttc gtgatgttta ccacatgtat accatcaatt taagtggaat atctgccatt 7800 gaaaaaataa tttctgatcc ttcttcgtgc aacagtcagc ttttaattcc attgcaacac 7860 ttgttgagat atcctataca tttagcacgt gtttgtaaaa tgttacggaa atatccattt 7920 ttgaatggag attttcggat ggcggtcaaa acacttgacg attttcgaga gttatgttct 7980 tatatagacc aagaaaaagc ccgcgaggaa agttatcaag tacttagtgc actgtgtgga 8040 aaccagggtg ttgcggtgga cattccaagg catataaaat ttaaagggtc agttattcca 8100 gctacttcat ttatttatga ttttaatgcc tgcgtctttt gcgacgatgg attggttgtt 8160 tggacgaggt atgttaaaaa aatcgaaatg aaggccgttt cgatagaaca atgtcttcga 8220 gtagatgaac tttcaaactc tattttagtt tgtactttaa atatgaaggg gaagctttta 8280 aaccgtcatt tggcacctca aactatggct gcttctgttt ttcttaagtg gtatcatgaa 8340 agagctggta tctcaaatgg caaagaaaat aaattaaacc gattgaaagt tgtcaatgct 8400 aaaacataaa ctaatttctt tctttttctt tttttaatat taaacgatat tttttttcta 8460 ttattcactc gttacctaaa atttgctgaa cataatgaca aatatgttaa accaaaattt 8520 attgtcaact tacttcttca ttcttgttat ccttgtctta ccaactttga aagatatttt 8580 cctcaattaa aaatttactt ctcaccttcg ttaccttaat atgggcatta ttattaacca 8640 aatagtttaa ataatatctt tatcctttaa taatatttat tggtaattct tgtttacaat 8700 tcctcgtctt tttattgaag tgagagtcta ctatatatga gtttaataac tagctacaca 8760 agttagcaaa ataatattgt agttcgtctt actgggaaag acatacatgt gcataatgag 8820 aataaacctt aaaacaagca acaaataaaa ctagtcctct tcgtctgcat tgtcatcttc 8880 gaaaagagtt gagtacgagg tagcgtttga aagtgacctg cctttacatt tctctaaatg 8940 tgcagcatat cgagacgcag ctatttcacg cttgcacatt aaacaagaat aataagggac 9000 atttgaagga gtttggacgc tattaccata tatatcgtag cctggcttgg tacaatactg 9060 ccgacaatgc ttgttacagg ccggacattt ttgaagagat aatttagcat tcttgtggac 9120 tgtttgggtc aattcatggg tgtagtcttt caacaaattc tcaaatatag tgcaagactg 9180 attgaaattt gaagttagtg aaaaagttgt acaagtgtta aattcagcca cctattgaca 9240 attgtttttc tattaatctt ccttttgtct ttaaagtact acaatttgac atgttaaata 9300 aaccgcgatc gattaaatga tacatgcttt cataaacaag caaatctttt tttggcgagg 9360 aagtttaatt ttgaaaggaa aaacaattac acatagagaa atcaggtact tacaataccg 9420 gcaagagaag caggctgcat ctttaaacca ttctttggga atcaaaagtt gagtattcca 9480 agcaagttag tattgttaca aagccggtga ttccaaaatt tcaaacaatg aggaaaaaga 9540 tgcaactgat ccgtatggga aattgagatt tacagaacgg aagtgcttca aattgatgtc 9600 tttattataa aaattattag gctcaaatac ttggtgttac atctttagct tgcgtaggag 9660 ctgactttat ttgctaatag tgagtgttga tataatttgc taatttcata cttctctgac 9720 tccaagagca atgcaaaata cacacgctca tgaaataaaa tatcagtaat ccacttgcgc 9780 aattggaaaa aacaacgcct acaacatagt acctaagttt ctccctttta caattcatca 9840 aatcatacat tcttcagctc gactaaggat aaattgtatt cattaaatac ataaaatgtt 9900 aaaagtcata aaataattcg ctagtaaatt aagcaaaagg ctaaactgta tgccgggatg 9960 ccatcaatct caaatgattt aaataataca atacaggcaa ggatattaga agtagttttt 10020 gattatagac aaagtgtttg ttaccaaaaa agagccaaat ttagatatgg cattttggca 10080 acccgagcaa taaataaaga catagcttcg aatgatgaaa aatgaaggat atacaagcga 10140 aatgccgaag aaaaaaagaa atagacacaa acaaaaaggc gatgcgatgt tggggtaact 10200 acgattgaat cgacacatcg tcattattgg cattagaggg tgggatattt aaatttctgg 10260 ttgagatatt ggataacgag gatgagtagt tgggtactga agaaagagct cgttgcacac 10320 ttgaatttga cctttgacca ttaagggaag atatcggaac agattgtgta gatactggag 10380 attcatttgg agcattattg aaaagccaca aatatatttt cccatcttca gacccactga 10440 ctacctcaca gtctccaaga gcaaccgagg ttacaggctc cgagtgattc ttcaacgtgt 10500 gaacacattc acaagcctcc caaactttaa caacaccatc atgagctccc gagattaaac 10560 gaaggtgatc tgccgcaatt tcccatacac cttcaatgtg tccaaacaat gtatgaacac 10620 attttttctt ctcgatgtcc cattgcttta ttgtgccgtc caatgagcaa gaaaacaatc 10680 gcgaatcagc aagagctaaa ctctggacag ggccaatatg agcactgaaa gtatgaagac 10740 acgtgtttgt ttccaaagac caaatcttga tggtggaatc gtcggaaccg gaaagaacaa 10800 gtccacgatc tctaattatg cggacagaat tgacaggtcc tgtgtgaccg cgtaaagtga 10860 tacgcttacc gccagaaaag tgccacagct taactgtaca atctgcgctt ccagaaacaa 10920 gtagcgtaga gtcaaacgtt aagcataaaa cactatccgt atgaccatgt aaaatagaaa 10980 tgcattcaga ggttctgtag ttccatatac gaatagtttt gtccattgaa ccgctgataa 11040 gtttacactg atcgaattga aggcacgtaa caccactgct atgaccttct aatagagcaa 11100 cttgttgaaa ggtagcaaga ttccataatc gtatagtggc atcataactg ccgctagcaa 11160 gaatgttcct tacaagttgt agacacataa caccgtcaga gtggccactg agaacaacct 11220 ggcgacaacg accatgccgc cagttgcatt caactctaca acgttcagca tatacttctt 11280 tccatggtct ggttttaaag ggaagaaaga atttggaatc ggagttcgga gaaggtggtt 11340 tgacagaaga aatagtctct tcattactcg acgtcggata atcgtccagc tttgcttttt 11400 tgacgggtga agattcatga gcctgatcga cgcctctttt tgtaagtcgt tcataacgtt 11460 tttgtatgga agcctttgct gcgtataagg tatttctttc gagtaacgga agtccccagc 11520 cgcatttttc acattttcga ttaatatgtt gttcacacat ccgatgccat ataacatcat 11580 catcagcaag ttctttccaa tgtttactga cttgtgcagc ttggcaaagg cttctagcat 11640 ccaaaaaaga taaaatgcga aacgaaattt caacagggag caaagagaga aaatctaagc 11700 gtactagaga atctaatgtg ctggaggcaa aagagagaag agaggacgaa cagttgttta 11760 aaatgccttg caaagcgagt ttacgttcgc tgcaagaagc ctctgaaaaa gcagcccata 11820 cagcttcgac acgttgacga cttttttcgc ttaaaccaga caattcatta tgcattgaag 11880 aaatattaaa agccgaaacg gagatggatt gatcaccttc ttttttttcc agtaaatggc 11940 gttgccatag ctctgctcgt ggtgcaagat tatcagaggg ttcggaagtg ggaacagatt 12000 cataacctgt agtcattttt tttataaagg ttaaatatta agtatgaaaa gaaagaaggg 12060 acaatgcaaa ggttgatttt agggtaaaaa aaaatagagt ggataatagc acaaaaaaat 12120 gttatcacgg atgatgcggg tagatgttaa cagaatgaaa ccagaaatga tttggataag 12180 atgatagtag tataaaagac tatagtaata caaaaaaaaa ggagaaaact atatgaagat 12240 tgtaataatt atgataagcg gggaaagtca actatcgaac cttacaaagt aatttgtaag 12300 taaatcgaaa atttaaagtg ctagctgata gaaatatatg gaaacaagaa aaaaaattta 12360 aaaagagaca caaactatgt aaaagataaa cgaaaaagaa actagaagat caaatataaa 12420 atacacacaa actcgttgct ttggcaacct tcagtaaaaa gatgaagagt tgaggtagaa 12480 ccaagatttt aatgattcaa aaaactccaa taatactctt tatccaacca cttgattatt 12540 ccaaatatgt gtattttctt gaggtggctt tcgatgaggt taaggaggag aggatataat 12600 atagagagga ttgtgaggcc taaagactaa taatcaccta atgaatttga gattttgagt 12660 agaattgcga gatgttaagc gaatctcaaa attacgaatc cgaagataat gtggataaaa 12720 caaattgcaa agatgtcgtt ctattcgtct cagtatatat atgtgcgtag atcattaaaa 12780 atctgtccac ttctcagtta atgcaattga tttcgattaa ccaactattg cgcaatctgc 12840 cactcatatt gaaaattttt actgatctgc aaacgtttaa cagctatttt ccactagatt 12900 aataaaaaat agccaatcct cacaagtcgc acctttttcg gggatcgggg gaaatgtcgc 12960 tgaaggtgtg aaaatgcaaa ttttctcgga tgtcaacagt ttaatcagtc gcttcaaagt 13020 ttgtatattt cttaattttg gtgaatttcc tccatatttc ttcactttgt atggcggcaa 13080 tggagccgta atgctaagca aatcgtaatt gagtttgtaa tagctagcat cagtttaaac 13140 tcgaatgaat taagtaaccg cttatatatt cataaaaact tctaagtaat tgagctaggt 13200 gcgtttatag ggatgattat tcgctcagaa aatgattaaa acactgctca acttgttcac 13260 ctatatatag ttgtcgtaaa caaagctaaa tcgatgattt attacaagaa gaaagaatac 13320 atgattttcg gttaatcaca taacatgaac aatattgaag aaggaaatag cgatttattg 13380 agccgctgtt tttttcatga ataccggtta acatagattt ttaagtataa ataaaaggat 13440 aatgactagc ggtttcattg ttcatctttg attgaatatt gttaatgtca cgtacgcgtg 13500 aaatatataa agtcgccgag gaatatgcat atagtctgca tatacattat tttgagaaca 13560 tatattaatt taaattgttt ttgtcacaaa ttcaatataa tattctatgc ataattaatt 13620 catcaaaacg actgttgacc tatgatttgc ccttaatgtt gactgattac aagtgatgga 13680 catatattaa ccaaatattt tttacacaac taaataaata tgaacgttgg tgatttgaaa 13740 agtgccaatg acttgtatga atctgtacgc tcaatagaag gagtgactgg tgtccattta 13800 tttcgaataa gagatgcagg cattttgaag agtactatga taccagagtt agacgcgtta 13860 accacaatta gcttggatga attaaacaag tctcctaccg ttttcactaa aaatttactt 13920 caaggttgcg gtggaactga tcttgatgtg ccagcggaat tgaagagatt ggtgattttc 13980 gtatgcaaca ttttggaatc ctgcaacgag ttcaccgatt taggctcagc aaggttgtta 14040 cgattgactt tcgattcttg ccaactggtg attatgtatg gtatgctaaa cgcccgaatt 14100 ttattttatc ttatttttta aataaaaagc gtaaataaag caataaatta actagaaaat 14160 ttagattctt tgttcgttgt tgcaattaca aaggatgaaa cataaaactt ttttttgccg 14220 ttcttatcaa taaaattaat tttattaatg tttgaatcta tggtaaatta atttttataa 14280 aagttttagc tcgtttaagc aatgagaagc ttcgcgtgct ttgtttgggt atcctgggta 14340 tcactgataa tacgctaccg cgctacagca actttttatt ttcatatttg tcttgccaaa 14400 gaccttcacc caggttggga ttctactggg tctttaaatg ttaaataaac gcttaactat 14460 tcaattgcct ttttatgcta cccaaaccgc ctcatcgtct agattttggc gagttctttc 14520 cccaaagtct cgaactggaa tagcacttta tgcttctcta atattgcttt gcatattttt 14580 tactatattt tctactatga gccatcccag tcttcaatgc tttagtccta cttccttggt 14640 aggagcacaa cctttgaaaa acctcacaca cttgattatt gttgccggtc atgcggtttg 14700 gttaggcggg tctactaatg gggaagacga ttcagaatgg attcttgagc cctaccaaaa 14760 gggggaagga aaagtatttg cacaacatgt acgatcgggt ttagacttgt tatctcaaga 14820 tgattcctct ttgttggttt tttccggagg tcaaactaga aacggtgctg gtccttcttc 14880 agaagcccaa tcttattatt ctttatctat gcaaattaat agtgatgaag gtttggctgc 14940 cagacggact accgaagaat tcgcccggga tagcttagaa aatgttctat tttctgtcgc 15000 tcgtttttat gaagttacat ctagatatcc acaaaaaatc actgttgtat cgtttgattt 15060 taaaagggac cgatttttga atctgcatag aaaggccatc aaatttcccg aacataaatt 15120 tcattttgtc ggtatagatc cggaaggtgg ggtttccgat gctactcgtg aagctgaaag 15180 aaagaacgct atcattcctt ttacggaaga cccatacgct tgtagtaatc cactactggt 15240 taagaaaaga atggagcgca atcctttcag gagacagcat tcgtatttaa tcacttgtcc 15300 tgaacttatt cccctgttac agtattgtcc atcagatcca tcaaaattct ttaatggaaa 15360 actgccttgg taacactctt tgtgatctat atcagtcttt ttctatacat tctttataac 15420 ctatcatatg atcctgaagc tacattggat ctatgcgata aaagtaaggc gttcttttca 15480 ttctttcact atgaccttga gatgcgagtc atgcaatttt ttttattttt cattctgctc 15540 tctaggctaa ttgtacacct aatgcaacta attttgtcaa aaaaattgaa caaagaaatc 15600 tctaaatgta atcattaagt gtaaaattat aaaaattcat aaaaatttat cattattcaa 15660 tgtttctaat gcatgagtaa ccagtagcaa tgatcaaata ttatgatcag ttgtcgaaaa 15720 tttgtcaaga aaagagtcga tgcaattata gaccttgaaa tgttagtttt gatcataaat 15780 atttagaaat aatacctctg aaggctgttc aagcatcgaa caatgtccag tatcaatttc 15840 tttaaaagtg taatttccag gataatcctg aaaaaaaact ttatccttca aagatgaaac 15900 agggtcctat gataaaagtc agtctttacc aattaaattt tgaatttaaa cgtacaaatt 15960 ctccaaacaa aataaggata ggacatttag gaaagtggaa ccctggttct agcaattctt 16020 caagacccat gagcattgtt ttccaaatct ttgtattgct ctgtctattc caaagccata 16080 actgtgctcg tacagcatca ccgtcacctt taatgttttt tgatagtgac ctggtgactg 16140 agctgctgcg tagtccatga aaacgatcaa gcaatctata taagctaatg aaagcatttg 16200 gtgttttcct caaacgaact atcatggaaa tctctttgct tgtgaagcga atcttaggat 16260 tgagcaacaa caatgcggta cagcgagttt ggagcatttt agacactctt gaagcaatgg 16320 ttgctcccat tgaatggcca atcaatatga attgtgtatt ttcaggaaat aatttctcaa 16380 ggaccttgta cgtgagtttc gatagtcctt ttgttgttaa ttgatcgact gaaccgatac 16440 gctgatttgg aaaagcttgt cgtgacagac cgcaacccca ataatcgaag gaaaagagac 16500 aagcagtagg tggaaaatag ctcatcactt tttggaattg agacatctgt cccccaagtc 16560 catgaaggaa aacaaacact tcctgcttag caagattatg atttaatggt ataatgcctg 16620 gacgcaagta gtaggccacc ttgtattcat ttaataattg atagtcacta gatatatcaa 16680 tcttggagtt gtgggaattg tcgtttggag ataggttttt agagagactc tctctctttg 16740 accttctttc aatcactaaa cgttgaaaag acttagctaa atatgcatca tatagataaa 16800 gaaacgtaag tatcccaagc gctcctaaaa tcccataact tataaatgag gtaagtctgg 16860 agattgtaaa gaaatacata tgtatgtatc ttactgcaaa agtatattgg aaatgaagga 16920 attactttat cacgtttttt taacaatttt ttggaaattg cccgccaata atgatagtaa 16980 acagatgtat tacagacttg ggagaattcc gttgagattt attgtatcac tgcgacaccc 17040 aacgccaggt gactatacca agttactcaa tatgaaattc gataattaat ttgttgtcgc 17100 gaatattact ttaaatatct atcaattgtg atttaaaaaa aaagctctaa tatgtactca 17160 aattgattaa caatgtcttt gttcttaaat ttgtttcatt agtaactaga aaatcagttc 17220 aataaaatat taccctctcg tacaaggcta cgaataaaaa cgactatagg tatagtctta 17280 ttctctgaaa cttagaatca tttaatgtgt gattccttgt acattgcgat acgaaggcaa 17340 atgaacagca attccagtgt ccctgactga ctgcacgaaa acagatatat gccagctata 17400 catattcgta caattaaaac acaaggtata ataaaatcat gatagactta tatattgata 17460 gcaaagtaat gcaaatcaag cctatttatt tagtttaaag caaatagagg ctggaatttc 17520 aaaaataaaa tattttaacc catctggtgc atacttagaa agagcgacaa agaaagcaat 17580 aggtatacgc ttcataccct aacaatattg tatatacaca aacatctcaa gacaaccgag 17640 cgaatgttta gtagtcctac aaaaaggccc cacactgtag ctcttccttt gaactcacga 17700 ttttcagaga cgtattctat caagatacag actatttata tggaaaagtt atcaggaata 17760 gcattaataa aatggaaaat ggacaaagtc atagggaaag aagacgtgtc tagaagatag 17820 tccagcatat aaatacgtat cacttgtcaa atacgagcat tactttgaag agaaaatgca 17880 gtattataat atcgatgaat caacaaggac aagatgacga caagcaaata aatcgaaaat 17940 atgagtattt aaaaagtacg aaattttaat ttattcctct ttggcggcag cagcagcagc 18000 aggagctgaa gctttaccag ttttttcacc attagctagt ttagtgtcgt actcttttct 18060 ctcacgttca taacgttctt tgtcctgacg agctttttcc tcgtatggct aaaattgggt 18120 tagtgataaa cgagaacaaa acaaatcaaa gtattagaac aaacacccag acgccttata 18180 taattcagat acaaacacat ttgcatttga cacgaaaaaa aaataagagc cctaaaatgc 18240 gtgcgtctcc aagtaattta ttattgaatt tttaacttta aacaaaaaat ttggtactca 18300 ttgcaaacgt aataaccaat actcaacttt tcaagtggag gtagccataa tcacttgtgt 18360 ataacgcgta gatgctgcca taactacaaa aacatcttac ctcacgttct gtgcttgtaa 18420 gctctttcca tcttttgccc aacaaagatc ctagctggcc taaacgcgtt agcttttgac 18480 tcttttaaca tcaacacaag aatgatagaa taattaattt ttactccaat gaaacatacc 18540 aaaggtggca tcagggttgt ctgttttcat cttttcgcgg ttctcaatgg aaaaaaacat 18600 aaacgccgac atattgcgtt taggagtatt tggatctttt ttacggctgg attttgcggc 18660 tctaggcatg attgtatgcg tgttttgttt aggtgcttat aatattattg atggtagtat 18720 gtggaatgtg tatgtgtgcg ctcccttagt atgtaacgag ttagtacatg acatcataaa 18780 tggctatgta agtaccagca ctaaaatgcg taccatagaa aacaaccaca ataagttatc 18840 tgtaacatga tgtaacgtgg tgagcttata gcatatgacg aagaacagca cagtgcataa 18900 aaaacaataa ctttgtcagt tagatgttta ttttcgaaat aacgatactt tctactacgg 18960 tttgattata tatagtaata aaatcagtca tagcccaaaa atgagtataa aacaaagatt 19020 caatttaatt ctgtttcaag tagcttaagc aatgtctcag ttataattaa gctataggaa 19080 ggtcaactat ttttgcttca ctatattttg tattctgaag aacatattga tgtgtaggat 19140 cgatagcgta gcccagtcaa gcaatcgaga actgtaaacc tatgttgact gtgcagtcgg 19200 aaatatgtga aagacgcatg gttctaaggt tgatattttt ttatttttac tgttaaagtt 19260 gattcttgta tggttgatat ccaccagaaa tatacaagtt cttaattcag tcaattctga 19320 tcattgcaaa ttccactgag aacttctgaa atgcaagctt ggtcgtactg gtaaagaaat 19380 aggacttaat attaactcat gtgaaattta aaatattcag tacgatacat tataagtgat 19440 gaagcaaaaa actattgcta ttattcaaaa cctttaaaat tcgtatagca aaacttatag 19500 ccgaatattg ttacgattta agcattaaat tacgaggtca tattgtacaa aataactgca 19560 tgaaacgact atttattcat ccaaaattcc taatataacc aatccgaaaa agtttatttg 19620 tccagtgtct ttgaagtatt tgtaaaacaa acaaacaaac aaaattaatc cattttactc 19680 cgaagcggcc gaaggcttct cttcagaagc gttagatgac ctttgcttct taaattttct 19740 tcctctgtta ctatatttac caggacgctg acgatccatc tctttaaaag cgtcaaaacg 19800 tctgcgtttg ctgctaaact ttggtggatc gtttttatgt aattcagctt tcatgtcaac 19860 atactccttt ttgctcatta tagtgagctc gtcctcgccc catttcaaag gtgcagtttt 19920 gactttctca agaaatttat tagcaacatc gggttccttg aattcaacaa atacgcttcc 19980 cttaaatttt ttatcgtcat cccttctcat acggacagca ctaatgggac cagcattttc 20040 ttcaaagaat ttttccaaag caatttgagt gtcatctttt tcatcaccga aacctttgca 20100 gtagacactt ctttccatga cgctcttgtt gtctacacga actagaggaa tcatacgacg 20160 tactttttcg ccagcttcat cgacttcaag aagttcagga ctcttgcgaa gagcatttac 20220 aatggcttcc aaaggctgaa aacgacgcat acgtttgaaa ttagcaattg tttgaatggg 20280 aacccatcca tcattttttt gagaagtagt ccataaaaat ttatcatggg gtaagttggt 20340 gtccgaaaaa taaaattcta ttcatactgt tagtaacgac cactcaacac aaaaaaggtt 20400 ttaatccaac gtaaacaaag tgtgtaacat accaacttgc tttaaaactt cagcttcatc 20460 aaaagataaa tctttttttc catcatcttc cttcttttca gtagtttcct cctttttttc 20520 ttcactagta gtatcttttt gactttctac tacttttcca gcttcctcgg ccttgggaac 20580 ctctgaagaa ttctcctgct tagatgagat gtccttaatt tcttccttct gttcttcagt 20640 tgacatgatg ttaattattc gtagagagac aggcaaaggg caaatttcat aagaagttgg 20700 attcctctcc tagaagcatt tctaacccta ccctattatc gaactgacat tattttccta 20760 ctcatgaaga caatgttaaa agttggcact taaaaaagaa gtagtttatt cataatagat 20820 ttataataga tagaataatc ccatgaattt ccattgtttt tttttttgaa aagattaaca 20880 gagattgctc cttacaatgt agctctggat acaatttaac cataatgaca agcagtagct 20940 tttagttttc ctatttatga ttctttaccg acaattgcaa tataacctat aatatcaaga 21000 ttccccattc gaattatcat ttaatatcca ctttattgta gaaccgctaa ctattaaaac 21060 cgatgtaaga cattaatact ttaaacttac tccatttgtt ggagtcatta tatgttcgtt 21120 acgagatcac tatcaaatgc tttaattgaa taatttcaat ttcatattgt tgaaggattt 21180 taaatagtaa acggagcgcc tcgaaaattt taaatttcct ttataactga cataggtgta 21240 agattaacaa tttctttctc catgttcata acgtcttctt caggattaga tgcattatcg 21300 gagggtggag attgtggttg attattttcg tcagatgtag tcgatggttt ctcattagtt 21360 tcggcgtctt cctcttcaga ctcccctacc atatcttgat aaatttcggg gtgtttttga 21420 aaacaagcct gcatagcttg aaatttgtca agacattcca taccttttgg ttcactcttg 21480 gaataaacga agcaactaaa agctgctttg aattcttctc cacatggacc atgagccata 21540 cctccaagac agggacaatc ccagttaatc tctccagtat ccggattaaa tgctgactcc 21600 tcgctgctct cctcctccac ttcctcaaat ttcctagcat attcatcatc atctttacca 21660 gtggctattt gttctcgaag tatatttcca gctgtctccc cgctggattt ttccttatca 21720 gttttcttcg gtgcactatt ctcagtagcg ctgaccttgc ggcctttctc gtcagtcgaa 21780 ggttgtgttt cacttgtcat tttcttctca atggcatctt caattcggtg tcgctgcata 21840 tatggttcat tatacgctat attgttagtt aaattcatat aatcgtacag aaaaagatag 21900 ccatttcaaa catatgatac ttacattgtg tttccgtatg gacatgttcg cctacaacag 21960 gatggtcatt atcttgactc gatgatgcat ttgaagtgtt ttttccaagt aaatatccag 22020 cagtcaaaga agcagctgca acgccagata caataggcaa aaaacggcct ttccatacat 22080 cagttttggt tgcagtacca aattttcgac aaatgcctgc ttgaaatcca tttctctgca 22140 gtagagacct tctcatatta ttgtaaccgt taatccttat acattttgga aatctgaaaa 22200 gtaagttttt agcaaacatg gtttttttga tttatgggaa gttgagctct gaacttctaa 22260 tgtctgcgta atggtcagaa agcggcgacg atcttacaag aacgtaactt tgtcattcat 22320 tctaagttta tataagtttg catgtttttt aaatcagatt taagtaaata ggtattcaca 22380 aatgtaagac aagcaagact ggcaggattt acgagattac taagaaatgc ctgaatgact 22440 aatttcataa tagaattaaa ctagcgacat aatagtttca caagcaaact taggtatgca 22500 aaacaaaagg taattcattt ataatattta attagaagaa cgtgagtatt attttctata 22560 atatgttaaa tttttactat aataatgtac cagtaaacga cactgaattt tttctttaaa 22620 agaaatatac tgacatccca atctattctt ccttgccaat tatgtcaacc caacgtttgc 22680 ccttaagctc ggcaagaatc tcttgcttaa tcttgtgagc aattacagga ccatcatatc 22740 ccaaagcagt ataaacttga accatagttg caccagcacg agcatactca atagcatctt 22800 tgccagaaga aataccacca cagccgatga tgggaatatc ggaagaaaga tgcttacgaa 22860 gtgtgcgaag agtatttaat gcgataggtt tgagaggagg tccagaaaga ccacccgtct 22920 cttcaacatg gctagttgat ttgagggtct tagggcgttg aacggtagta ttaccaacga 22980 tcacaccgtc aatcttgcac tttttgagga catcggcaat gtccgtgagt tcttcttcgt 23040 tcaaatcagg tgcaattttt acaagtacgg gaggatgagg agagttcaat ttattgcgct 23100 cactgacaac agcagtcaat aaagttgaga gggcagattt cttttgtagg ttacgaagac 23160 caggggtatt aggagaggaa acgttaatga caagaatgtc agcgaagtta ccaaaggtac 23220 gaacaccttc aacataatcc tcaatctcgt taccgttctt attcttgcct aaattgatac 23280 caaggaactt gttaggaatt aaactacgag gtacgccaag gacagcggga tcagtgcaag 23340 aagcgggatt tgcatcaaac tgttttaata gttgaggaga tgtcttagca atgtatttgc 23400 gaacgcgctt ttgaatctta gcaaggatgg catcatggcc gatagaatta aaaccgtaac 23460 gattgattac agacaaatca ggcttaaggc ggaaatagcg tggtttagga ttaccaggtt 23520 gaggtttagg tgtgaccgag ccaatttcaa gataggaaaa cccgaagttc aacaaacctg 23580 agatagcatc ggcttgttta tcgaaaccag cagctagacc aatgggattg caaaatttct 23640 taccccaaac ttcaacggca agagatggat catcagctac acgatccttc ggtgttatac 23700 cccaagaggc agcgagaatg gcgacacgat gagaaaactc aggagtggtg aaagcatgaa 23760 agagaggcat ttcaatgcgg ccatggataa aactacgaac atcggacatg tcgtaaatgg 23820 caacgccggc agtaaaacta ccaataacac tcaaaagctt ccaatgacgg agaaagaaat 23880 tgccatttga agagccagag ctggtagatt gaaaacgtac agaggagcgc tttaaaccct 23940 gagcgacacc gcgaaacaaa gatcgttgat acattttagt atttttaata gaattcggct 24000 taaataaaaa attttcaaaa cgaaattgaa aaaaatatga atgataaaat aataaaatga 24060 agttttataa tagtttatgc ttaatatatt taaacaccag tttttttcca aacacaacaa 24120 acccaagaaa aaataaacag aaccaaaaaa taaaaatatg gatttaagga tcagaacaga 24180 atcgtcaatc cgtttcttta tccacctaga gacaagaagt gttaatttat ataaaatgga 24240 gaacttggtt ctaataagat ttcaacgaaa acaaagattt cagaaccgaa aaaatttctc 24300 caagtgctag cagaggtata ttctctgaga aagaacaaaa atcaaaaatt gaatgtttat 24360 attgaatgtt acctgtaaca ggtaacatgt ttttttagta atgccgggct gtcgaaattt 24420 gactatgagt tttgtaaata aagcgatggt tataaacaat tttatgatag tttttgcttt 24480 cgaattaaca tttcataaaa aatttgaaaa agaaaaattt taaaaattta aggacaaaat 24540 ccacttgaaa aacaagtgcg aacagctttt tgcaaaaaaa ctacaaacca ctacacatta 24600 gcgaataagc ctattaggaa tttattttaa tttttgttga tttaaatttc tttttttttt 24660 aaatggttag aatctagttg ataaacttct agcaatgtat ttccaaattg tttctattac 24720 gttcgttgat acaggcaatt gttcatttct ggtatgacta aagcatttct atacaattca 24780 acttctcatt ttttctagct gtatttatga tgtacagagc gttgggagag agttgattaa 24840 gtcaatagta tttatgaatg agacaaggaa cactcatact atatcaatga taaatagctt 24900 ttatattatc ctgttataat cataaaaatt aatttcatct atatagactt agaaaaaaat 24960 ggtttcgttt tcactgtcct taaactacaa atatcgtaca cgtgttactt gttcttcagg 25020 tgtaccctca ctattgtcaa atcttatgaa attctttact cgttgacttg attgttatgc 25080 gaacagtatt ttcgcaaatt cctcgtttta aacaagtcaa tcagtacata cggatgtcga 25140 caaggcagtc agacattagg tttgttagat agaagacaga cgttgactaa cccatatagc 25200 aacttcttca tttcttctgc ttcgcacaaa agcgagcacg tggaggtttc tcaatcgtct 25260 tctgattcca aaaatgttga tgggagaagc acaagcgaaa agagaaaggt cgaatcagtg 25320 aaattagtcg acgagtcgaa acacaacaac cacgacgaca ctggaactca aaatgttgag 25380 cgtgaaaata atattgtgtc tgaggcaaaa aagcaaaaga ctttaggttc atcctcctct 25440 tcttcagatg ccgtatctag taacaacgat tctggggcat ctactccaat acctttgcca 25500 atcaaagaac caccgttaga gtccaatgct cgcaatgata agttaaaagg tcatgcaaca 25560 tttgctgaaa tggtaaaagc attcacaaaa atagagaata ctagcaaacg gttggaaatc 25620 attgatataa tggggactta cttttttgga attcttcgcg accatcccag cgatttactg 25680 gcctgtgtgt atttaagtat caataaggta tgaacgtttg gttttaaagg atttctcctt 25740 ctcagtacta acgtcttttt ttacattagt tgggcccaga ttactcggga ctagagctag 25800 gaattggcga aagcattata atgaaggcta ttggagagtc tacagggcaa acgcttcaac 25860 agattaaact atcgtttcac aaagttggtg atcttggtct tgtagctcaa acatcccgtc 25920 aaaatcaacc cactatgttt aaacctgcag cgctgacaat tccattttta tttgactcat 25980 taaaaaaaat tgctcaaatg agcggaaacc aatcccaaaa tagaaaaatt ggagtgatca 26040 agcggctatt gagttcctgt gaaggtgcag aacctaaata tttgattcga gctttggaag 26100 gcaagctacg cctccaactt gccgaaaaaa ccattttagt agcattagca aatgccaccg 26160 ctcaatatca tgctgataag aatggagaaa aactttcgca acaagacagg attgaaggag 26220 agcagattct tcgagatgtt tactgtcaac tgccttcata cgaccttatc gttcctcact 26280 tgattgagca tggacttggt actttgcgtg aaacttgtaa attaacacct ggaatcccaa 26340 caaaacccat gctggctaag ccgacgaaac aaatttcaga agttttgaat acgtttgatc 26400 aagccgcatt tacatgtgaa tacaaatacg atggcgagcg cgcccaagtt cattttaccg 26460 aagatgggaa gttttatgta ttttctagga attctgaaaa catgtctgtt cgctatccgg 26520 acatctctgt ttctgtatcg aagtggaaaa aaccagatgc tcgttctttt attctcgatt 26580 gcgaagctgt cggttgggac 26600 //