ID SPAC328 standard; DNA; FUN; 25985 BP. XX AC AL360054; XX SV AL360054.1 XX DT 30-JUN-2000 (Rel. 64, Created) DT 01-JUL-2000 (Rel. 64, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c328. XX KW AAA family ATPase; alpha,alpha-trehalose-phosphate synthase; KW Importin-beta family member; metal homeostatis protein; ribosomal protein; KW RNA binding; rps5-2; tps1; TRIAD composite zinc finger; KW ubiquitin carboxyl-terminal hydrolase; yeast msn5. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-25985 RA Saunders D., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (29-JUN-2000) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; P40387; P40387. DR GOA; Q9P3T6; Q9P3T6. DR GOA; Q9P3T7; Q9P3T7. DR GOA; Q9P3T8; Q9P3T8. DR GOA; Q9P3T9; Q9P3T9. DR GOA; Q9P3U0; Q9P3U0. DR GOA; Q9P3U1; Q9P3U1. DR GOA; Q9P3U2; Q9P3U2. DR SPTREMBL; Q9P3T7; Q9P3T7. DR SPTREMBL; Q9P3T8; Q9P3T8. DR SPTREMBL; Q9P3T9; Q9P3T9. DR SPTREMBL; Q9P3U1; Q9P3U1. DR SPTREMBL; Q9P3U2; Q9P3U2. DR SPTREMBL; Q9P3U4; Q9P3U4. DR SWISS-PROT; O14116; YKX1_SCHPO. DR SWISS-PROT; P40387; TPS1_SCHPO. DR SWISS-PROT; Q9P3T6; RS5B_SCHPO. DR SWISS-PROT; Q9P3U0; UBP2_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c328 is overlapped at the 5' end by cosmid c3A11, CC EMBL entry SPAC3A11, accesssion number Z99260 and at the 3' CC end by cosmid c16E8, EMBL entry SPAC16E8, accesssion number Z98529. XX FH Key Location/Qualifiers FH FT source 1..25985 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c328" FT /map="IL" FT misc_feature 1..98 FT /note="Nominal overlap with SPAC3A11 S. pombe chromosome 1" FT CDS join(complement(2945..3037),complement(1..2861)) FT /db_xref="SWISS-PROT:O14116" FT /label=SPAC328.01c FT /note="SPAC328.01c SIMILARITY: S cerevisiae, MSN5_YEAST , FT Importin-beta family member required for nuclear export of FT Pho4p and involved in pheromone response pathway, (1224 FT aa), fasta scores, opt: 879, E():0, (26.2% identity in FT 1028 aa overlap)" FT /partial FT /gene="SPAC328.01c" FT /product="putative Importin-beta family member; yeast msn5 FT homologue" FT /protein_id="CAB95996.1" FT /translation="MDEKGLSNILQALNVVHSPESSRETRFSAQQLLDELKDSYSSPSV FT AIQLLELNEQAFSSLGCKLDIHIVQHFSLSLFETSVGMNWKSFSNKEKESVTSFLCKIS FT LEDNNLLSVHFVRSKLASVFIEIAKRDWYNTWREEFDSFLQSLWSLSLQHRQLSSLILR FT GIMEDLYQYDDPVASLRSHILFNALISILSSSSTLHKLYPSGLPYSVTIPSNNEGWLIR FT WGNALESQDDALECLKCFKSCLSWVATDSIREANIVSHICQILVQGPIFLKTHAIDCIY FT ICVTRTMEIDDPLWEIVEEMLSPSSLYTLHQVYTATSESINIKTLSSTTPEYILLKKLS FT ETIVALGQYNYLDSNRRKCIKLTSLDTYSLLVLEIMKHPSLLISAISQHFWVLALRDPI FT ISKHEKFQIVYPELLSIASERLLRFEDAVVELIPESATAKYLQEDVEGVSAVHSFCGNF FT RRFMFDIVRLTVSITPIESLNWIQNRFQSTVLGNMEDIQSQTEFFSKTSPLYLTMDVGF FT STIEAFLHGVTRWNENTSDDPATYEIILQNLFLWCKQLVEINFKDPMLITRLISVLVLF FT TSILARENTTLLGVVLEKIISAVTYDNTSASYGFSDVQKINEMRSRCCFELVRLGELMP FT NPLMNIFDQLQSIIDQLDNATTLTGSEIVMLKTFLFVITQFSDVNIEVKNEYFEKLVGP FT VVKTWLDVQPPVNSPMEFLNHIGFPQMAEYLSAKYPYNADYTQFELDADAASYQSNLET FT GRKWLWPIKCLGRFCEATCSNKHIHPSEFEGQKNLWQVILPNVVPNLLKLVEQLHCCYE FT PSFISGLGMHNSSILQKSIVERFWLHGVSQISKNQFLEESYKMDVSANKLIHSFGHFLR FT RLREYCYYAIASFMRLGQAFFCVPGLSKQFLTAFFSHAAGLSLHQWTSMVNVVIKPYCV FT NCPAELRDECLLPLLPALLSELDHKLVSEWRRINDRGLLVEEDAEETGEDDDLS" FT misc_feature complement(2862..2878) FT /note="ctaattatcgtttttag, splice branch and acceptor" FT misc_feature complement(2939..2944) FT /note="gtaagt, splice donor sequence" FT CDS 3791..5305 FT /db_xref="SPTREMBL:Q9P3U4" FT /label=SPAC328.02 FT /note="SPAC328.02, len:504, SIMILARITY:Homo sapiens, FT Q9UEN0, ariadne protein, (463 aa), fasta scores: opt: 1427, FT E():0, (44.7% identity in 465 aa)" FT /gene="SPAC328.02" FT /product="protein of unknown function, has a TRIAD FT composite zinc finger domain" FT /protein_id="CAB95997.1" FT /translation="MSDLLDDEFYEEEFENDLLDASEFEDEFDEDAEIDDDGFTVERKR FT RRAHSVSYRVVSVRDLRASLNEKINQLTSIIDLTREQVLGLYRYFKWNRERLLERYIDA FT PEESLQKAGVGLSGSKQREVVHHEGTCEICYDEGCLPFFSAECDHEFCLACYRQYLDSR FT ISEGESVIQCPEESCTQIVSIQSITKVLDEKSLDRYHRLLDRSFVDDNDHLRWCPAPDC FT EFAIECHVTQASLSSVVPTVTCNCGKQFCFGCGHDNHQPTICPLVKIWLQKCQDDSETA FT NWIHANTKECPKCSTTIEKNGGCNHMTCKKCKYEFCWVCLGPWTEHGNNWYTCNRYEEK FT SSTSARDSQSKSRASLERYLHYYNRFANHEQSAKLDHELYEHTHKRMTQMQVDSNLSWV FT EVQFLKNAVDILFQCRQTLKWTYAFAYYLARNNQTEIFEDNQRDLELAVENLSELCERP FT CQDCSLSVFKQRVLDKTVYVRSRRDVLLDDTARGLAEGRWEYVVDV" FT misc_feature 4181..4315 FT /note="Match to PF00097 zf-C3HC4, Zinc finger, C3HC4 type FT (RING finger) Score 30.16" FT misc_feature 4379..4582 FT /note="Match to PF01485 IBR, IBR domain Score 69.80" FT misc_feature 4640..4762 FT /note="Match to PF01485 IBR, IBR domain Score 23.64" FT LTR complement(6344..6552) FT /note="Tf1-type LTR fragment" FT CDS 7544..9085 FT /db_xref="GOA:P40387" FT /db_xref="SWISS-PROT:P40387" FT /label=tps1 FT /note="SPAC328.03, len:513" FT /gene="tps1" FT /gene="SPAC328.03" FT /product="alpha,alpha-trehalose-phosphate synthase FT [udp-forming]" FT /protein_id="CAB95998.1" FT /translation="MSDAHDTIKSLTGDASNSRRLIVVSNRLPITIKRKDNGTYDFSMS FT SGGLVSALSGLKKLMTFQWLGWCGQEIPEDEKPMIIQRLQDECSAIPVFLDDETADRHY FT NGFSNSILWPLFHYHPGEINFDEENWEAYRAANYAFAEAIVKNLQDGDLIWVQDYHLMV FT LPQMLRELIGDKFKDIKIGFFLHTPFPSSEIYRVLPVRNEILEGVLNCDLVGFHTYDYA FT RHFLSACSRILNLSTLPNGVEYNGQMVSVGTFPIGIDPEKFSDALKSDVVKDRIASIER FT RLQGVKVIVGVDRLDYIKGVPQKFHAFEVFLEQYPEWVGKVVLVQVAVPSRQDVEEYQN FT LRAVVNELVGRINGRFGTVEYTPIHFLHKSVRFEELVALYNVSDVCLITSTRDGMNLVS FT YEYICTQQERHGALILSEFAGAAQSLNGSIVINPWNTEELANSIHDALTMPEKQREANE FT NKLFRYVNKYTSQFWGQSFVGELQRIQHYSHPHPRRTNPILRTKSAQVLSMNSSS" FT misc_feature 7598..8992 FT /note="Match to PF00982 TrehaloseP_syn, FT Trehalose-6-phosphate synthase domain Score 1040.06" FT CDS 10139..12364 FT /db_xref="GOA:Q9P3U2" FT /db_xref="SPTREMBL:Q9P3U2" FT /label=SPAC328.04 FT /note="SPAC328.04, len:741, SIMILARITY:Schizosaccharomyces FT pombe, O43078, putative proteome subunit., (660 aa), fasta FT scores: opt: 1435, E():0, (45.7% identity in 613 aa)" FT /gene="SPAC328.04" FT /product="AAA family ATPase with similarity to katanin; FT putative microtubule severing protein by similarity" FT /protein_id="CAB95999.1" FT /translation="MSLEDCYNVTQSYAAVAIHKEQTADYVEAIALFQKAKRNILMNPE FT FKYARERLHVMDYEDRHYVETLLCMLEQLTIRIEFLTKEIAQQEAAYKDIQNTQKSLVT FT QSSTGSANVAYISGNGPGDRSFIDDGNYSASSFERQNRTAPLQSKVTTASLKPNIPRTS FT MSSSPTASRTSLRKGAGELETHSAVKSAKKASVKSKSVLPPSKSLARTGLPAEVSTQNN FT ANRAALLAWGSLNSSKPKHALPPSYISSEAAQASRSSFQVERHRPTPDNSAVIEAARRT FT YSSISSSSSPFKKKTQSHLPNRTTEVPSISKQLSKSSTSIATVAPSLASVSSVTKSPSP FT TPQSAPRAQSASTETAQDLDFLTPPRLSVNNPFLSDLYPASEQGLSSCEEKDSPVDGDE FT FFNHTNEEEIIEKQFQSTSISAMTSEKQEQILRECPDIDEELGKSILREIVVSGDEVHW FT DDISGLEFAKHSLKEAVVYPFLRPDLFQGLREPARGMLLFGPPGTGKTMLARAVATESR FT SVFFSISASSLTSKFLGESEKLVRALFTLAKKLSPSIIFVDEIDSLLSARSSDGNEHET FT SRRIKTEFLIQWSSLARAAASRQTADHPRVLVLAATNLPWCIDDAARRRFVRRTYIPLP FT DETTRRLHLNNLLKYQKHSLSLEDIEAIVKATEYYSGSDLTALAKDAAMGPLRSLGESL FT LFTKMESIRPINLDDFKTSIKVIRPSVNLQGLERYSEWDKEFGSQGH" FT misc_feature 11618..12202 FT /note="Match to PF00004 AAA, ATPases associated with FT various cellular activities (AAA) Score 256.32" FT CDS join(12925..12928,12982..13295,13471..13572,13612..13758, FT 13812..14037,14140..14204,14286..14732) FT /db_xref="GOA:Q9P3U1" FT /db_xref="SPTREMBL:Q9P3U1" FT /label=SPAC328.05 FT /note="SPAC328.05, len:434, SIMILARITY:Zea mays, Q41834, FT nucleic acid-binding protein precursor., (303 aa), fasta FT scores: opt: 364, E():7e-15, (39.3% identity in 168 aa)" FT /gene="SPAC328.05" FT /product="Protein with 3 RNA binding domains; yeast hrb1 FT homologue" FT /protein_id="CAB96000.1" FT /translation="MGMGSKLDVSSSLNSSSSNMDRDRSESPKRHVNGSNSLKRGLHFD FT GEHTERDPHLGNGQKYTQQERRVYVGNLSYQVRWFELKEFMGQVGNVLNCEILNLPNGL FT SKGCAIIEYSTAEEARTAIKTLSNQKFMGRLVYIREDREQNARFGSSSVSPSASSNGKD FT SEPDRQLFVGNVSSISNPLYSFPRTLLPYNVRWQDLKDLFRQAGSVIRADIQMNQEGRS FT RGIGIVVMSSMKEAMHAIQMLHNTDFMGRTLEVRLDRFAHHKIEDLVYHAYPHGPCSDC FT IYVGNLPWATSDRNLLDLFTDIGSVIRARIAYEPTGRSKGFGVVQFENENDAASSIEKL FT NGYRYGGRPLQLSYAHYATPLPAVPTVLSGLPSVAYTPPVMHIPTTNSPLTPQSFTNSF FT LGYLPISMPVANMPAIAPISVALPENNIEHSLEPS" FT misc_feature 12929..12934 FT /note="gtatga, splice donor sequence" FT misc_feature 12954..12981 FT /note="ctgatcaaatagaatgaatttgattcag, splice branch and FT acceptor" FT misc_feature join(13179..13295,13471..13566) FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 41.07" FT misc_feature 13296..13301 FT /note="gtaagt, splice donor sequence" FT misc_feature 13459..13470 FT /note="ctaatatatcag, splice branch and acceptor" FT misc_feature 13573..13578 FT /note="gtaaga, splice donor sequence" FT misc_feature 13597..13611 FT /note="ttaaccttcgtaaag, splice branch and acceptor" FT misc_feature 13759..13764 FT /note="gtattt, splice donor sequence" FT misc_feature 13799..13811 FT /note="ctaacgagtatag, splice branch and acceptor" FT misc_feature 13812..14009 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 65.72" FT misc_feature 14038..14043 FT /note="gtaagc, splice donor sequence" FT misc_feature 14128..14139 FT /note="ctaatactcaag, splice branch and acceptor" FT misc_feature 14205..14210 FT /note="gtatgt, splice donor sequence" FT misc_feature 14272..14285 FT /note="ctgactgaatatag, splice branch and acceptor" FT misc_feature 14286..14477 FT /note="Match to PF00076 rrm, RNA recognition motif. (a.k.a. FT RRM, RBD, or RNP domain) Score 77.81" FT CDS join(15555..18914,18999..19064) FT /db_xref="GOA:Q9P3U0" FT /db_xref="SWISS-PROT:Q9P3U0" FT /label=SPAC328.06 FT /note="SPAC328.06, len:1141, SIMILARITY:Kluyveromyces FT lactis, UBP2_KLULA, ubiquitin carboxyl-terminal hydrolase FT 2, (1221 aa), fasta scores: opt: 847, E():0, (32.7% FT identity in 834 aa)" FT /gene="SPAC328.06" FT /product="ubiquitin carboxyl-terminal hydrolase" FT /protein_id="CAB96001.1" FT /translation="MATVKNLRIGKSPNRLIQDLDVFDSPSAGWNDPWSPHSSRYHWQL FT HSNLGESAVFDENDFWCVCQKTRKHLHVKVRRDRGKPLIEEPEENYGIKDRIPVYYEEE FT ELPEPHVTSPTKSEFATTSTCMKWSSKTTKSEIEVEWRDSYLDANCIKEIIDSRRPSFA FT SLLTKKSSSHQGSSHSSQPSLFTTFTSLELFLRNVLVHNDQRAISAAPEGTFERHVGKG FT RQIQSLMKSLLFEYHHENVNYVPTIADAPLTDEQKLNLYLARNELIVLANHFRDTKEDP FT AIVANPFPVRLARPALINAFGVPNYDSVVPMYTTVFRDNSASLPDDPAFIALGITNDYP FT DSFVRYFYEEQKKNDEANVRVYADALAHIYNLRKSSFLRDLIAADRKNGIVSSDVIQAA FT YSSLGLEAEVGPDYRYSQEKIFEAFHSALLRKPEFARAIRNDLETIGYARKSSEILNYV FT LSTEQAFYTVNEAYQWLGIKSNTEDAMVASVALVKFEDDSDKAIEAVKWIAEERNSSIL FT YDFLASQGRPSNKKPKEVPMDEDLAYNTLGVQDRALSDDVLINVYGFAVEDHPEQSDTL FT RAALKCIGEVRNSRLITHYLEHGNLDIPPEVSSLDTPIGLENTGNLCYLNSLIQYYFII FT KPLRNAILDIDENKDLNMIENKEAVKKVGGRIVTRIEFLRALQFTYELRKLFIELITSK FT SSSVHPSSVLTYLALIPLTLDQVKSGTSSVMDLSSSRELSNLNERSITIDPRAEEQAQG FT LEQEQGQDEAKSPAEQSSSVNLIDFPMANTNGESQTQPHYFEVSEEEINSSMDLGRQQD FT VLECIDHVLFQLEASLGRISNSEDRLGSDNDLIRRLFSGKLKQTLNDASQGVRSNYEIF FT SHLIVDLFEEKQTLYDALDGVFETVNIDMGSETAQRSLCITELPIILQLQIQRVQFDRT FT TGQPFKSNAFVEFGKELSMDRYVEDTDGKMAPLLQRYWDLKREIINLQKRQQLLLTTNS FT NLMSSVDTLSILSKWAAQQQDSRLPINPKLPDILQEEINNVVAEVDMLKKQEASLKEER FT THLFDNYISHSYDLLAVFVHRGQASFGHYWTYIHDFENNVYRKYNDEYVTVVDESEIFA FT DTTGNNANPYMLTYIRKEYRHIIECVHREHNLLL" FT intron 15928..16011 FT /note="Intron predicted by HMM_intron, Score=5.81" FT misc_feature 17397..17489 FT /note="Match to PF00442 UCH-1, Ubiquitin carboxyl-terminal FT hydrolases family 2 Score 50.18" FT misc_feature 18732..18911 FT /note="Match to PF00443 UCH-2, Ubiquitin carboxyl-terminal FT hydrolase family 2 Score 67.88" FT misc_feature 18915..18920 FT /note="gtaagt, splice donor sequence" FT misc_feature 18984..18998 FT /note="ctaacatttatctag, splice branch and acceptor" FT CDS join(complement(20697..20714),complement(19813..20628)) FT /db_xref="GOA:Q9P3T9" FT /db_xref="SPTREMBL:Q9P3T9" FT /label=SPAC328.07c FT /note="SPAC328.07c, len:277, SIMILARITY:Saccharomyces FT cerevisiae, BSD2_YEAST, metal homeostatis protein bsd2., FT (321 aa), fasta scores: opt: 335, E():1.4e-14, (42.7% FT identity in 124 aa)" FT /gene="SPAC328.07c" FT /product="putative metal homeostatis protein; yeast bsd2 FT homologue" FT /protein_id="CAB96002.1" FT /translation="MSTNSNQNSIHTPIPEFPENRSTNRSELAAAFEPPDDDVEYSETA FT PLYSSARASIEGEEAFYQHLSTPDPGNDSGHVRSSNDRIPSTSSNHADGHHVDSVFSNL FT SAKPTVESNTEELEEEPPSYEQAAADTAPPYWDTTMVIPDYGSNEIYIDGMSVGTGFSF FT VWSACVAILFPFVGFLVTYVLSTTHLGRYGAQIGLSLTLFQRGYIMISESGMENNDDQY FT NYDELPHQKLIGSILIIIGWCLVLVDTFGFIRIRRMKNAISRTDSPGETSPEEVV" FT misc_feature complement(20629..20646) FT /note="ctaacaaatctattttag, splice branch and acceptor" FT misc_feature complement(20691..20696) FT /note="gtaagg, splice donor sequence" FT CDS join(complement(22383..22413),complement(21736..22301), FT complement(21322..21504)) FT /db_xref="GOA:Q9P3T8" FT /db_xref="SPTREMBL:Q9P3T8" FT /label=SPAC328.08c FT /note="SPAC328.08c, len:259, SIMILARITY:Arabidopsis FT thaliana, CAB80655, hypothetical 38.3 kd protein., (345 FT aa), fasta scores: opt: 246, E():1.5e-08, (22.7% identity FT in 277 aa)" FT /gene="SPAC328.08c" FT /product="conserved hypothetical protein" FT /protein_id="CAB96003.1" FT /translation="MSEKFVELRKEFLTKLYKSTPSEQTSRSEKETWLEEKSKYLGEMT FT RELNEVQDQIAPYDRRVCMEQLVDLTRRLQQIRHDILPRQPFRFQRALHVKSSQKPVKN FT ITVNAEAPEVYFENDTLYLANLKNQNIGDNVIPYPNNKAVKVSAKSLRSCNISISNCSS FT VNLHNATKCNFTFPTIQGSIHLSDINDSTICVSCHQFRLHHSTNLRVHLRCKTSPVIEE FT SKEISFSYKDEHPILDFTWARSDPSPHFRITSDLFDA" FT misc_feature complement(21505..21518) FT /note="ctaacgccttctag, splice branch and acceptor" FT misc_feature complement(21730..21735) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(22302..22319) FT /note="ctaactacttttttgtag, splice branch and acceptor" FT misc_feature complement(22377..22382) FT /note="gtatgg, splice donor sequence" FT CDS join(22940..23005,23277..24107) FT /db_xref="GOA:Q9P3T7" FT /db_xref="SPTREMBL:Q9P3T7" FT /label=SPAC328.09 FT /note="SPAC328.09, len:298, SIMILARITY:Saccharomyces FT cerevisiae, YO7L_YEAST, putative mitochondrial carrier FT yor222w.putative mitochondrial carrier yor222w., (307 aa), FT fasta scores: opt: 1100, E():0, (56.1% identity in 294 aa)" FT /gene="SPAC328.09" FT /product="mitochondrial carrier protein; yeast yor222w FT homolog" FT /protein_id="CAB96004.1" FT /translation="MPHDNIPFPVTFAAGAVAGISEVLTLYPLDVVKTRMQLSVGKSDY FT NGTFDCLKKIVKNEGPHRLYRGILPPILMEAPKRALKFASNDTYSKLWRKVFKRKDSSP FT ALSILTGSCAGFTETFVVVPFELMKIRLQDVKNASKYNGTVDCFTKIVKQERILALYNG FT FEATMWRHVVWNAGYFGVIQKIRNSLTPASSRIGEIRNNLIAGTIGGIFGTFLSTPFDV FT IKSRIQTVPRIAGQVPKYNWAYPALVTVAREEGFTALYKGFVPKVLRLGPGGGILLVVF FT NSVIEFYKRCLVHNASA" FT misc_feature 23006..23011 FT /note="gtaagg, splice donor sequence" FT misc_feature 23258..23276 FT /note="ctaactctttctttttcag, splice branch and acceptor" FT misc_feature 23268..24074 FT /note="Match to PF00153 mito_carr, Mitochondrial carrier FT proteins Score 217.17" FT CDS join(complement(25507..25616),complement(24717..25218)) FT /db_xref="GOA:Q9P3T6" FT /db_xref="SWISS-PROT:Q9P3T6" FT /label=rps5-2 FT /note="SPAC328.10c, len:203" FT /gene="rps5-2" FT /gene="SPAC328.10c" FT /product="40s ribosomal protein s5" FT /protein_id="CAB96005.1" FT /translation="MAASIIPKEVSLDETGHIKLFNKFPFEGVEVKDISLVDYITIGNG FT QPLPHTAGRFQTKRFRKARCFIVERLTNSLMMNGRNNGKKLLATRIVKHAFEIIALLTD FT QNPLQVLVDAVAACGPREDSTRIGSAGTVRRQAVDVSPLRRVNQALALITIGAREAAFR FT NVKSISECLAEEIINAAKGSSNSYAIKKKDELERVAKSNR" FT misc_feature complement(24720..25181) FT /note="Match to PF00177 Ribosomal_S7, Ribosomal protein FT S7p/S5e Score 221.05" FT misc_feature complement(25219..25232) FT /note="ctaactttatttag, splice branch and acceptor" FT intron complement(25219..25506) FT /note="confirmed by mRNA" FT misc_feature complement(25501..25506) FT /note="gtatgt, splice donor sequence" FT misc_feature 25884..25985 FT /note="Nominal overlap with SPAC16E8 S. pombe chromosome 1" XX SQ Sequence 25985 BP; 7984 A; 4757 C; 4961 G; 8283 T; 0 other; tctgacaaat catcatcctc tcctgtctcc tcagcatctt cttcaacaag taatccgcga 60 tcgttaatcc gccgccactc actaactagt ttgtgatcta attcggacag caaagctggc 120 agtaaaggta aaagacattc atcgcgaagt tctgcaggac aattaacgca atacggtttg 180 attacaacat tcaccataga cgtccattga tgtaaactta acccagctgc atgagaaaag 240 aaagctgtca aaaactgctt agacaatccg ggtacacaaa aaaatgcttg acctagacgc 300 ataaatgaag ctatagcata ataacagtat tcccttaaac gccttaaaaa atgaccgaac 360 gaatgtatta acttgttagc tgagacgtcc atcttgtagg actcttccaa aaattgattt 420 ttagaaattt gacttacacc atgcaaccaa aatctttcaa caatactttt ttgaagtatc 480 gaagaattgt gcattcctag accacttata aatgaaggct cataacaaca atgcaactgt 540 tcaactaatt ttaacaaatt tggaacaaca tttggcaaga taacttgcca taggttcttt 600 tgcccttcaa attcagatgg atgtatgtgt ttattactac aggtggcttc acaaaatctc 660 cccaaacatt taatcggcca taaccattta cggccagttt caagatttga ttgatatgaa 720 gcagcatcag catccagttc aaactgtgtg taatcagcat tgtaaggata ctttgctgat 780 aagtattcag ccatttgagg aaacccaatg tgattcaaaa actccattgg actgttaaca 840 ggtggctgaa catcaagcca agtcttgaca accggtccaa ctaatttttc aaaatattca 900 tttttgactt caatattgac atcagaaaat tgagttatta caaacagaaa tgtttttaac 960 attacaattt cagagcccgt taatgttgta gcattgtcca attgatcgat gatagattgc 1020 aactgatcaa agatattcat caaagggttc ggcattagtt ctcctagtct cacaagctca 1080 aagcagcatc tactccgcat ctcattaatt ttttgaacat cggaaaatcc atacgatgcg 1140 gaagtgttat cgtatgtgac agcagatata attttttcaa ggacaacacc aagcagggta 1200 gtattttctc ttgcaagaat ggatgtaaat aacactaaga cactgatcaa acgagtaatc 1260 agcatagggt ctttgaagtt aatttcaaca agctgtttgc accacaaaaa cagattttgt 1320 aaaattattt cataagtagc gggatcatca gaagtgtttt cgttccaacg agtaacgccg 1380 tgcaaaaacg cttctatcgt tgaaaatcca acatccattg taagataaag aggactggtc 1440 tttgaaaaaa attcagtctg ggattgaata tcttccatat tgccaagaac agttgactga 1500 aaacgatttt gaatccagtt taaggactcg atgggagtga tggatacggt taatctaaca 1560 atgtcaaaca taaacctacg aaagttaccg caaaacgaat gcacagcaga aacaccttcc 1620 acatcctctt gaaggtattt agcagtagca gactccggta tgagttcaac aactgcatcc 1680 tcaaaacgaa gtaacctctc ggaggcaata cttaacaact cagggtaaac gatttgaaat 1740 ttttcatgtt tggaaataat gggatccctc aatgctaaaa cccaaaagtg ttgagatata 1800 gcactgatta ataaactagg atgtttcatg atttccaata ctagtaagga ataagtgtcc 1860 agggatgtga gtttaataca tttccgtcga ttagagtcaa ggtaattgta ttggcccaaa 1920 gcaactatgg tctcagacag tttttttaaa agaatatatt cgggagttgt agatgaaagt 1980 gttttaatat ttattgattc agatgtggca gtgtaaactt gatggagggt atagagacta 2040 gatggggaca gcatttcttc gactatttcc cacagaggat catcaatttc catggttctg 2100 gttacacaaa tataaatgca atcaatagcg tgtgttttta aaaagattgg cccttggact 2160 aaaatttgac aaatatgtga aacgatgttt gcctctcgaa tggaatcagt agctacccag 2220 gacaggcagc ttttgaaaca ctttaagcat tctaaagcat catcttgact ttctaaagcg 2280 ttgccccacc ggataagcca accctcattg ttagaaggga tagtaacgga ataaggaaga 2340 cctgaaggat ataatttgtg cagggtggaa gaagaggata ggatgctgat aagcgcatta 2400 aaaagaatat gagagcgtaa ggatgcaacg ggatcatcat actgatacaa gtcttccatt 2460 ataccacgca agatgaggga agatagttga cgatgctgaa ggcttaaaga ccaaagtgat 2520 tgtagaaagg agtcaaattc ttctctccat gtgttatacc agtctcgttt tgcaatttca 2580 ataaatacgg aggcgagttt actacgcaca aaatgtacgg acagcaggtt attgtcttcg 2640 agtgatattt tacataaaaa gctagtgaca gattcctttt ccttattcga gaaacttttc 2700 caattcattc caacactcgt ttcaaaaaga ctaagagaga aatgttgtac tatatgaatg 2760 tcaagtttac agccgagtga ggaaaaagcc tgctcattca actctaagag ttgaatggcg 2820 accgatggac tgctgtacga atctttaagt tcatctagta actaaaaacg ataattagca 2880 aatattcatg gaccgtttcc gcaaagcacc atggctatct ccattatgac tcatcgcgac 2940 ttacctgctg ggcagagaac cgagtttctc gcgagctttc aggcgaatgc accacattca 3000 gagcttgtaa aatatttgat aaaccttttt catccatcaa aaccagttta ttgaaatcga 3060 gtcactgaaa ctcaaaaact gtttacttca ggactccttt gtgatgcaaa gaaatttaca 3120 aagataatca agtaatcaca agtattccaa tacttaggta ataaataatg aattttcctt 3180 aataataatc ttgaaacgaa gcaagatcgt aactgcgtgt tgggtgtttc aagaaacaat 3240 caagccagca tacaccgcat gtgtttagcc tgccattcat cgataacgat acattgcagt 3300 gtgttatata catagtcaac tttcttttct cgtttcaacc cccacttggt attgcagatg 3360 gaggctaaat ttctaatatt ctttgaatgc agcagcatcc atctcccgta cacttcgtta 3420 aaacattttt gatttggaaa gcaggagggc aattgtcttg ctcatttcat aaaggccaaa 3480 gccgaagtat tttacctttt gcatacatct ggctcttatt tttcagtctt gttacaggtg 3540 gccatttcac gacaagcttt actaaagatt tcacgattta ctcgtttgtt ttgtttgagt 3600 ggattccatc tgctgtggca tctcgtttgc ggtttaaaca attactttcc tgctcggatt 3660 atttgtaggt tttttgctta tataaggcaa ttcggcaaaa aaacaagtgg ttttgctgat 3720 agacaagcat tcattgtata cctttcttga atatcggtta aataaatttc ggtgaataac 3780 taaagctaag atgtctgacc tattggacga tgaattttat gaggaagaat ttgaaaacga 3840 tcttttggat gcttctgaat tcgaggatga atttgatgaa gatgcagaaa tcgatgatga 3900 tgggttcact gtagagagga aacggcggag agctcacagc gtgagctata gagtggtcag 3960 cgttcgcgat cttagggcct ctctaaatga gaagattaat caacttacta gtatcattga 4020 tttgacgaga gagcaagtgc tagggttata tcgatatttc aaatggaacc gcgaaagact 4080 gctagagagg tatattgatg ctccagagga atcccttcaa aaagcaggtg tgggacttag 4140 tggttctaaa cagcgggaag ttgttcacca tgaagggact tgtgagattt gttacgatga 4200 aggttgtctc ccatttttca gtgctgaatg cgatcatgaa ttttgtttag cttgctatag 4260 acaatatctt gattcccgaa taagtgaagg tgaaagtgtc attcaatgcc ctgaagagag 4320 ctgtacgcaa attgtatcca ttcaatccat cacaaaagtg ttagacgaaa agtcacttga 4380 ccggtatcat cggcttctgg atcgctcatt cgttgacgat aatgatcatt taagatggtg 4440 tccagctccg gattgtgagt ttgctatcga gtgccatgtt acacaagcta gtttaagttc 4500 ggtggtgcct acagtaacct gtaattgtgg caagcagttc tgttttggct gtggacatga 4560 caaccatcaa ccgacaatat gtccactggt aaaaatatgg ctccagaaat gccaagacga 4620 ttctgagacg gccaactgga ttcatgccaa cacgaaagaa tgcccaaaat gttctaccac 4680 tattgagaaa aacggtggtt gtaatcatat gacttgtaag aaatgcaaat acgaattttg 4740 ctgggtttgt ctgggtcctt ggactgagca tgggaacaac tggtacacat gcaatcgata 4800 tgaagagaag agtagtacaa gcgctaggga ttcgcaatcg aaatctagag cctcattaga 4860 aagatactta cattactaca atcggtttgc caatcatgaa caatcggcta aattggacca 4920 tgagctatat gagcatacac acaaacgtat gactcaaatg caggtggatt ccaatttatc 4980 ttgggtagag gtgcagttcc ttaagaatgc ggtggatata ttattccaat gtagacaaac 5040 ccttaaatgg acatatgcat ttgcctatta ccttgcaaga aataaccaaa cagagatatt 5100 cgaggacaat cagcgcgatc ttgagctagc tgttgaaaat cttagtgagc tatgtgaacg 5160 tccttgtcaa gattgttctc ttagcgtttt taagcaaagg gttcttgata aaacagttta 5220 tgttcgtagt agacgcgacg tccttctgga cgacacggct cgtggtttgg cagaaggcag 5280 atgggaatat gttgttgatg tgtaaattaa gaaagaaatt tatgatgatt caacagcaac 5340 tgttccctaa tttattttta cttccttttt tttcgactgg aagacactaa ccaatcctac 5400 gaattgaaat gaattaatta tcattcatta tttaatttac gaatgcatta ataaagaaaa 5460 aaagaaagaa ggaaactaaa atatatctct acagtacgca actttttgag atctgcgttt 5520 gatcgtcatg tttatttatt tcctcatttc attcatataa tagaatttca ttttacttct 5580 tttttggttt ttgttttttt tttctctttt tcctataaca tcacacaaaa aaaaaaaaaa 5640 aagaaaagaa aagattgaga gaaaagtgca aagcaattac ttacttgtat tactatatca 5700 tatgacgagc ttgttaataa caaacaattc catttatatt cttcttcgca ggtagtgaaa 5760 tatcgagttg tgagaatgat tttcttatgc ttgttttatt gatttaaatg attccaattt 5820 gtctttaaat cctgggtgtt aatttacagt cgtttcctgg ccaggacaga atagcgaagg 5880 gtcgaagata aggaagaaag aacaatgcga atgatttatt gaagcgaaat ctatcaagaa 5940 aacaaagcta tcgaatatgt agttgcgtat tagaaagggt tctaaattac tattgttcag 6000 ttgtttgggc taatttgttt tttatttttt ttttctcttc tgtgcctctg tctctttcaa 6060 cccaagtatg tgtagactta caaattccta atcactactg ctactttcaa tctcattaca 6120 caatgcgagt gtagcgaagg tacatctctg catctcttaa acttctgcat aaagaaggta 6180 taaggaatgg tatagaacct tgcgattact aaaatatcta attgtcctaa catttcaaat 6240 ggtgtaagga taatcgatga attagttcta tctacaagat acccaaataa gatcatttga 6300 tttattggga tatgattctc cttttatttt gtaggttgat gcgaatgtgc ctttttgttg 6360 aaatagctta aaactgaatt tcatttctca gttcagttgc agctctatat gtattctttt 6420 ctaataggtg atatcactgc catcctcgtt tagacggaag tcttatgcac gtgtcaataa 6480 gcgaagctta ttttagtatt cgaaaatggg acatatagtg gtacgcaacg tattccaaca 6540 ttgtgctgtg tatagccgag agtatattaa cgttgtgttt cgtgtcattc tttttccagt 6600 ttcctttttg ctttcgtcat aatatcatca ggcttcgttc gcactttttt agatgatatc 6660 accaagtaac atgtgtcaat acgtcgtgat attacgtcgg atgtaaacaa agcagatgct 6720 aaggaatgta aacaaacata ttaagggata aacaaacagt tagggtcttt atttctcact 6780 acaaatatac tagattctat atatttgatt cgttgaaaaa gatttttttt ttttttatga 6840 tattcagatt tcgattcgaa tccctttttt ttgcgcttct ccggttaata tttggaaaac 6900 ttttcccact gctggaagga tcctttttat cgttttttcc taatacattt atttagaaaa 6960 attttgtctt tcagttaaga tgctggtgaa ttgcgcacct gaacccttga aaacactaga 7020 catcttagta gagccggggt ttgatcagtg ttttaatgaa caaaaggagc tcctaaagca 7080 tatggttcaa gttaaattat tacttacaat taagcactct attatgataa atttaatgag 7140 tcgtctttta tatattttct ttcttgtacc gagtattata gggaaaagcg caggccgatt 7200 ctttaattca tttgcaaaga taagaaataa ttttttacat gaggtttttt ttaaaatact 7260 aataaatgtt tttgtaattt tcaaatatgt acctcataga tttttccagt cgattccatt 7320 tgttgtttac ctcatagcat aatggggtta gttttctctc tagcatacat aaccaactat 7380 ccctctgcat atcacattct acaatacatt tgcaagcaaa acctttgcaa attctaaaag 7440 attcaatctt agaatacttt atcaagttta gacagttatt ccttgtgctt gtacttgtca 7500 agaatctttg ttttgctgaa aaaaaaaatc cagaaatctc aatatgtcgg atgctcatga 7560 taccataaaa tcactcacgg gtgatgcttc taactctcgg cgtttgatcg tcgtctccaa 7620 tcgtttacca attacaatta agcgaaagga taatggcaca tatgacttta gtatgtcttc 7680 gggtggtctg gtcagtgctt tgagcggtct caagaagctc atgacctttc aatggttggg 7740 ctggtgcggt caagagattc ctgaggatga aaaacccatg attatccagc gtttgcaaga 7800 tgagtgtagc gctattcccg tctttttgga tgatgagact gccgaccgcc attacaacgg 7860 atttagtaac agcattcttt ggcccttgtt ccactaccat cctggtgaaa ttaattttga 7920 cgaggaaaat tgggaggcct atcgtgcggc taactacgct tttgccgagg ccattgtcaa 7980 aaatctgcag gatggtgatt taatttgggt gcaggattat catttgatgg ttcttcctca 8040 aatgttgcgt gaattaatcg gtgataagtt taaggatatc aaaattggct tcttcttgca 8100 cactcctttc ccaagtagcg aaatctatcg tgttttaccc gttagaaacg aaatccttga 8160 aggtgtactc aactgtgatc tcgttggctt ccatacctac gactatgccc gtcacttttt 8220 gtctgcatgc tctcgtatcc ttaatcttag cacactacct aacggtgtgg aatacaatgg 8280 tcaaatggtc agcgtcggca ccttccccat cggtattgat cccgaaaagt tctctgatgc 8340 tctgaagtct gacgtggtaa aggatcgcat tgcaagcatc gaacgtagac tacaaggcgt 8400 taaggtgatt gtgggtgtcg atcgtttgga ctacattaag ggtgttcccc aaaaattcca 8460 tgcctttgaa gtgttcttag aacaataccc tgaatgggtt ggaaaggtcg tgttggttca 8520 agttgccgtt ccttctcgtc aagatgtcga agagtatcag aatcttagag ccgttgtcaa 8580 tgagcttgtt ggccgtatta acggtcgttt tggtactgtt gaatatacac ctattcattt 8640 cttacataaa agtgttcgct ttgaagagct ggttgctctg tataacgttt cagacgtttg 8700 tttaattacc tcaactcgtg atggtatgaa tcttgtttca tacgagtaca tttgcactca 8760 acaagagaga catggtgccc taattcttag tgaatttgcc ggtgctgccc agtcactcaa 8820 tggtagtatt gtaattaatc catggaacac ggaggaatta gcaaactcca ttcatgatgc 8880 cctcactatg ccggagaaac aacgtgaggc taatgagaat aaattattcc gatatgttaa 8940 taagtatacc agtcaattct ggggtcaaag ctttgtcggt gagttgcaac gcattcaaca 9000 ctacagccac cctcacccca gaagaacgaa tccgatttta cgaaccaagt ctgctcaagt 9060 gctgtcgatg aattctagct cgtaagagtg cattagcaac actattggtt tgttttccca 9120 ttaatcaagt tgttgcactt ttacactttt acttctataa tttcattctc aaagcaatta 9180 aatcatttgg tcatatatat tcgatgagtt agcagtttac gatacaaagg atgttgttta 9240 tactggcact ttttttattg agatgaattc acaatacatg atataatgca acgttcttta 9300 atgatttttt tatatgcaga aattccaatc agcttatggt ggtttgagta tttgctgatg 9360 atggaaattt gttagacaag tattcgacaa tttttttatg aagtgttgtt ctttgtaatt 9420 tcctttggtt ttatattgaa catgatggca aaaagaataa atgttttgtt atttaacctt 9480 aaaaatcctg taacattcaa ttaatattat ttttatacat tttttttggg atacacgtgg 9540 aagattgtga ctaatatatc ttataagtaa ggatgagaat atgctggact ggtgaacgga 9600 gttggaccaa gcaaatatta agattaatag tgaaatggtt ttaaaggtat tatttattgt 9660 aagtaaacta attttcaatt ctcatatagc aaaaagagtt tttttgtgta aatgatgaag 9720 atgcgtcatt tacccatcat tattcttcgc tacaccaaaa ccaaccgtaa agatttaaaa 9780 ctcaacaagc acagtgcgta tatcatagaa cttctattca cgcatataat tagtgctgtt 9840 gctagttttg tatttatttt tgtagacttt atcaagtttt ccgacaaaat cgtggtttta 9900 gtgagaaatt ttatctttaa ctttgtatca ctatatctac gatttgtatt tgcatgccgc 9960 attctgcttg tacgaaaaca atatttaata aggtaatagg atataaaagg agaagtgtag 10020 tttgtgcact tcagccaata tagaaagaga ataacgtttc caatcgagcc gatttaacct 10080 ctttccattg aaaggtaatt gtttttaatc agttgtagac gttaaagaat gcacaaaaat 10140 gagccttgaa gactgctata acgtcacaca gtcatatgcc gccgttgcaa ttcataaaga 10200 gcagactgct gactatgtgg aggctatcgc tttatttcaa aaggccaagc ggaacattct 10260 catgaatcca gagtttaagt atgcgaggga acgcttacac gtgatggatt atgaagatag 10320 acattatgtg gaaacattac tctgcatgtt ggagcagttg accattcgaa ttgagttcct 10380 taccaaagag attgcgcaac aagaagctgc ttataaggat attcaaaata cacaaaagtc 10440 acttgtaaca caatcttcta ctggtagcgc taatgttgct tatataagtg gaaatggtcc 10500 tggcgatcgc tcatttatcg atgatggtaa ctatagtgcg tcttcttttg agcgtcaaaa 10560 tagaacagct cctttacaat ctaaagtgac aacggcatcc ttaaaaccta atattccgcg 10620 aacatctatg tcctcttcac ctacagcttc gcggacttcg ttgcgtaaag gcgctggtga 10680 actagaaaca catagcgctg ttaaatctgc taaaaaggcc agtgtcaaga gtaaatcagt 10740 gcttcctcca agtaaatcgc ttgctaggac tggacttcca gctgaagtct ctacccagaa 10800 caatgccaat cgagcagctc tattggcttg gggatctttg aattcatcta agcctaagca 10860 tgctctcccg ccatcataca tatcatcgga agcagcgcag gcatctcgat catcgtttca 10920 ggttgagcgt catcgtccaa ctcccgataa ctccgccgtt attgaagctg cccgccgaac 10980 ttactcttct atttcctcct cttcctcacc cttcaaaaag aaaacgcaat cccatctccc 11040 taatcgtacc actgaagtac cttctatatc aaaacagtta tcaaagtcat ctacctcaat 11100 cgcaaccgtc gcgccatctc tcgcttctgt ttcgtcagtt acaaaatcgc catctcccac 11160 tcctcagtca gctccacgag ctcaatctgc ttccactgaa actgcgcaag atctggattt 11220 ccttacaccg ccacgtttat ctgtgaacaa cccttttctg agtgatctct atccagcttc 11280 cgaacagggg ctttcttcct gtgaagagaa agattcgccg gttgatggcg atgaattttt 11340 caaccacaca aacgaagaag agattattga aaagcagttt caatccacat ctatctctgc 11400 aatgacttct gaaaagcaag aacaaattct gcgtgaatgt ccagacatcg acgaagagct 11460 tggtaagagt atacttcgag aaatcgtggt ttcgggtgat gaagttcatt gggatgatat 11520 ttctgggtta gaatttgcta agcactcttt aaaagaggca gtggtgtatc cgttcttgcg 11580 tccagatttg ttccaaggct tgcgggaacc agctaggggg atgcttcttt ttgggcctcc 11640 aggaactggt aagacaatgc ttgcgcgagc tgttgctact gaatcccgtt ctgtcttttt 11700 ttctatttca gcttctagtt taacatccaa gtttttgggt gaatccgaaa aacttgttcg 11760 tgctctcttc actttagcaa aaaagctgtc tccaagcatc atttttgttg acgaaattga 11820 ttcactgctt tctgctagaa gcagtgatgg aaatgagcat gaaacatcga gaagaataaa 11880 aacagaattc ttaattcagt ggtcttcgct tgcaagagca gctgcatctc gacaaaccgc 11940 cgatcaccca agagttctag tgcttgccgc taccaatttg ccttggtgta tcgacgatgc 12000 tgctcgtaga cgatttgtcc gtcgtaccta cattcccctc cctgatgaga ccactcgtcg 12060 cttacattta aataaccttt taaaatatca gaagcattct ctttccttag aggatattga 12120 ggctattgtg aaagcaaccg aatattactc tggctctgat ttgacagcat tggcaaaaga 12180 cgcagctatg gggcctttgc gaagtttagg tgagtctttg ctattcacga aaatggagtc 12240 gattaggccg attaatttag atgactttaa aactagtatc aaggtaatcc ggcctagtgt 12300 gaacttgcaa gggctggaac gatattcaga atgggacaaa gagttcggat cccaagggca 12360 ttgagtctgt cttcttattt aaaattccta gcctgatacc gatttttttg gtaatcacgt 12420 tgaaaattta tttattgtct tttaatacat ggcttgtgca aacttatgat tataactaat 12480 aaggacaact tttgcctcaa ggaattattc atgatgataa taatggtgct gtaccaaaag 12540 cctttttgtt tactcctaat atattcgttt gtctcttttt tgttgataca atttatgcac 12600 agtctttgaa tttttcaaac acttaatatt aactgaggtt atctctaacc ctagttattg 12660 tttgagtttc catttttatt acgactcatt tacaaacaac taaaactcct tactatgatt 12720 aattagtcag tacatgtcaa tatttataat ttaaatgttt acagtttttt tattctattg 12780 ttcttttagc gaatctaaga gtttacagta tatcacttac gaaattatat tgcagttaca 12840 ctatagaagt caagttgttg ggatgcttta attatgtgaa gatgcacact cagcttatgc 12900 tcttgcgatg cctaaaccta tagaatgggt atgataacta ttgattgatt tagctgatca 12960 aatagaatga atttgattca ggaatgggta gtaagttgga tgtgtcaagt tccttgaatt 13020 catcgtcttc caatatggat cgtgacagat cggagtctcc gaagcgacat gtcaacggaa 13080 gcaattcatt gaaacgtggc ttgcattttg atggagagca cactgaaaga gaccctcact 13140 tgggaaatgg ccaaaagtac actcaacaag agcgtcgcgt gtatgttggt aatttgtcat 13200 atcaagttcg ttggtttgag ttgaaagagt ttatgggaca agttggcaat gttcttaatt 13260 gtgagatttt gaatcttccg aatggattat cgaaggtaag tttgcttcat agagggtggg 13320 tttcatgcga ctagtaaatc attgtctatt taaattgtaa cgttgaatcg atccaattga 13380 acgttacttt taaacgatta cttatggcct atagcttatc ctaaaatttg tcgtatactc 13440 agattgtgaa tagtctagct aatatatcag ggatgcgcga taattgagta ctctactgct 13500 gaagaagcgc gcacggcaat taaaactctg agcaaccaaa aatttatggg ccgtcttgtt 13560 tatatccgtg aagtaagatt ttttttatgt cgcttattaa ccttcgtaaa ggatcgagaa 13620 caaaatgcaa gatttggctc ctcttcagta tcgcctagcg cgtcgtcgaa tggcaaagat 13680 tctgagccag acaggcaatt gtttgttggt aacgtaagtt caatttctaa tcctctatat 13740 tcttttcctc gaactttggt attttaatga attgtggaat tgcaaataag aaatggtact 13800 aacgagtata gttaccgtat aacgttcgct ggcaagattt aaaggatttg tttagacaag 13860 ctggttctgt tatccgagct gatatccaaa tgaaccaaga aggccgatcc cgtggcattg 13920 ggattgttgt catgagttcg atgaaagaag ccatgcatgc cattcaaatg ttgcataaca 13980 ctgatttcat gggccgcact ttagaagttc gcctagatcg gtttgcacat cataaaagta 14040 agccgtattc cactcatgga aatggctata cgtttccagc ggaaatgcaa atgactacat 14100 catccaccta tctacccatg ttaggtgcta atactcaagt cgaggattta gtttatcatg 14160 cgtatcccca tggaccctgc tcggattgca tttacgttgg aaatgtatgt atataaggac 14220 gcttttgtgg gattagtttt ccgcatcatt ttaagttttt tttggagatt actgactgaa 14280 tatagttacc ttgggccacc tcagatcgca atttattgga cctattcaca gatattggct 14340 cagtcattcg tgcccgaatc gcctatgagc ccactggccg atctaaaggt ttcggtgtcg 14400 ttcaatttga gaatgaaaat gatgcagcat cctcaattga aaaattaaat ggttatcgtt 14460 atggcgggag acccttgcaa ttatcatacg ctcactatgc gactccacta cctgctgtcc 14520 ctactgtgct ctcgggtctt ccttcagtcg cttatacacc acctgttatg catatcccta 14580 caacgaattc accactaacg ccccaatctt ttacaaattc tttcttaggc tatctaccga 14640 tttcaatgcc cgttgcaaac atgcccgcta ttgctcctat ttctgtagct ttacccgaaa 14700 ataatattga acattctttg gagccttctt aaaaattcgc caatacatct gaacttcttt 14760 tctctttaca attaagcaca tttccgtagt gtgaatggct agctcagtga cgacatgcgc 14820 aatgttctaa ggcagttatc ctaatattgt ttgcttttct ctattttttc ttcaaatttt 14880 tgctttaatt cctaatcccc aaatattctt attttccatg tttatagatt tatctctttt 14940 gtttgatttc aattttttgc taagatctta ttcttttccg tgacacacca aagtatgctg 15000 atggcatata tattcgtctc tcgttcttct aattgaagtc tttttaattt tagctttact 15060 gtttttttac aggatgccta gtttccttct tttacaattg ctaaccattt catggtttta 15120 atgatatttt agatttttag acttccattc tgttaacttc cagttaacca agtttaatct 15180 ttattgatta actacattat ttttaaagta aggtgtattt aggttaaaaa tcttatttaa 15240 gcataatggt aaatttcgta tagcgaaatg taggtgttga ttgtttctta ccttctttag 15300 tagccttatc aatgaaatac aaacatttac ttctatctta ttccccacat tcataaaatt 15360 gatggtcgca tacctggctg gcatatgtaa gacgacaagc atcatacgca tgaagtctac 15420 ctaccgagtc ctttactcat gaaaaatcct tcaatctgta cgttctttcc gtttggacgt 15480 tttttcaagt atttttcata ataaaaaatt taaatttctt tattaaaatt atttacatca 15540 aactataaag aggaatggca actgtaaaga acttgcgaat tggcaaaagt cctaatcggt 15600 tgattcaaga tttagacgtc tttgatagtc catcagctgg atggaatgat ccttggagtc 15660 ctcatagctc aagatatcac tggcagcttc attcaaattt aggcgagtcc gctgtatttg 15720 acgagaatga cttttggtgt gtttgtcaaa aaactcgcaa acacttacat gtgaaagtcc 15780 gaagagacag ggggaagcca ttaattgaag agcctgaaga aaattatgga ataaaagata 15840 ggattcctgt ttactacgaa gaagaggaat tacctgaacc tcatgtgact agccctacga 15900 aaagtgaatt cgctactacc tctacttgta tgaaatggag tagcaaaaca acaaaaagtg 15960 aaattgaagt tgaatggaga gatagctatc ttgatgctaa ttgtatcaaa gagataattg 16020 attcccgacg tccatcattt gcttcccttt taactaaaaa atcgtcatct catcaagggt 16080 catcccattc atcccaacct tctcttttta ctacatttac ttctttggag ttgtttttac 16140 gaaacgtgtt ggtccataac gatcaacgtg ccattagcgc tgccccggaa ggaacttttg 16200 agagacatgt cggaaagggc cgccaaattc aatctttgat gaaatctctt ctgtttgaat 16260 atcaccacga aaatgtaaat tatgtcccta ccattgcgga cgctcccctt actgacgaac 16320 aaaaacttaa tctatacctt gctaggaatg aacttattgt tttggctaat cactttcgtg 16380 acactaaaga agatccggct attgttgcta acccttttcc cgttaggttg gctcgacctg 16440 ctttaattaa tgcctttggc gttcctaact atgatagcgt ggttcccatg tataccacag 16500 tttttcgcga caattcggcc tccttacctg atgatcctgc ttttatagcc ttgggtatca 16560 cgaatgatta tccagacagc tttgtccgtt atttctatga ggaacaaaaa aagaacgatg 16620 aagctaatgt tcgtgtttat gcggatgcgc ttgctcatat atacaattta cgtaaaagca 16680 gctttttgag agatctaatt gcggcagata ggaaaaatgg aatcgtgtcg agcgatgtaa 16740 tacaagccgc ttattcgagt ttaggacttg aagctgaggt aggcccggat tacaggtata 16800 gtcaagaaaa aatctttgag gcgtttcatt ctgccctcct aagaaaacct gaatttgcca 16860 gagctattag gaacgatttg gagactattg gctatgcaag aaagagttct gaaattttaa 16920 attatgtttt gtctacagaa caggcttttt atacggttaa tgaagcctac caatggttgg 16980 gcattaagtc taacaccgag gacgccatgg tagcttctgt ggccttagtg aaatttgaag 17040 atgatagcga caaagccatc gaggccgtca aatggatagc tgaagagaga aatagctcca 17100 ttttgtacga tttcttggct tcacaaggta gaccttccaa caagaagcct aaagaagtgc 17160 ctatggatga agatctagct tacaacacat taggtgttca agatcgtgca ctatcagatg 17220 acgttttaat caatgtatac ggctttgctg ttgaagacca cccagagcaa tcagacactt 17280 tgagagcagc tttgaaatgt ataggagaag ttaggaattc gcgtttaatc actcattatt 17340 tagaacatgg aaatctagat attccaccag aagtttcaag tttggatact ccgatcggtt 17400 tggaaaatac tggtaatctt tgttatttga attccctgat ccaatactac tttattataa 17460 aacctcttcg taatgcaatt ttggatattg atgaaaacaa agatcttaat atgattgaaa 17520 acaaggaagc tgtcaagaaa gttggtggac ggattgttac tcgaattgaa ttcttgaggg 17580 ctttacaatt cacttatgaa ctccgaaaat tatttattga actcattact tcaaagtcat 17640 cgtctgttca tccttcttca gtactgacat atcttgcttt aatacctctt acgttggacc 17700 aggtcaaatc tggaacatcc tcggttatgg atttgtcatc gtctcgagag ttgagcaatt 17760 tgaatgagag atctatcact attgacccca gagcagaaga gcaagctcaa gggcttgaac 17820 aagaacaagg acaggatgag gccaaaagtc cagcggaaca atcttcatca gttaatttaa 17880 ttgattttcc catggccaat actaacggag agtctcaaac acaacctcat tactttgaag 17940 tatctgaaga agaaataaac tcctccatgg atttaggtcg tcaacaagat gtcttggaat 18000 gtattgatca cgttttgttt caactggaag cttcacttgg tcgtatttcc aactcagaag 18060 atcgtcttgg ctctgataat gatcttatac gacgtttgtt ttctggcaaa ctaaaacaaa 18120 cactaaatga tgctagtcaa ggagtacggt ctaactatga gattttttct cacttgatcg 18180 ttgacctttt cgaggagaaa caaacattgt atgatgcatt ggatggtgtt tttgaaacag 18240 tcaatattga tatgggaagc gaaactgccc aacgatcctt gtgtattact gagctaccga 18300 taattttgca attacaaata cagcgtgtcc aatttgacag gactactgga cagcctttca 18360 agtctaatgc atttgttgaa tttggaaaag aactttccat ggacagatat gttgaagata 18420 ctgatgggaa aatggcacct ttactacaaa ggtactggga tctaaagcgt gaaattatca 18480 accttcaaaa acgacaacag ctattgttaa ctacaaattc gaatctaatg tcatctgttg 18540 atacattgtc tattctatct aaatgggctg cacagcagca ggattcgaga cttcctatta 18600 atccaaaact tcctgatatc cttcaagagg aaataaacaa tgttgtcgct gaagtggata 18660 tgcttaaaaa acaggaagcc agcttaaaag aagaaaggac gcatcttttc gataattaca 18720 tcagccatag ctacgacttg cttgctgtat ttgtgcatcg tggacaggct tcattcggtc 18780 attattggac ttacattcat gatttcgaaa acaatgtgta tcgaaaatat aatgatgaat 18840 atgttactgt ggtagatgaa agcgaaattt ttgctgatac tacgggcaac aatgctaacc 18900 cttacatgct tacggtaagt cgttattatt tcccatttga gggaaataat cattttctca 18960 aattttttcc agtttacata tagctaacat ttatctagta cattaggaaa gagtatcgac 19020 acataattga atgtgttcac cgtgaacaca atcttctgct ttaaaaacta tgtgaagggt 19080 aaaaactagg atggatcatc cgtgatcaat tgctatgaat ggaggttgga agttgtaacg 19140 tttttcacga tattaaagca tggaagctat gaattcatat ttcaaaaatc tatttataca 19200 taaaaattta gttatacttt atacatcggt acgggttaat aatctattag tctttactat 19260 aaagagaaaa tttttctatg acaaaattgc aaaaagtcta gcaaaaaaat tgaaatgtaa 19320 acaaacggct tttattatta aaatggcgat tatcgcaaat tttattataa gtagtaatct 19380 ttgacaaaaa atgtaattaa tagatgaaac tagtagaagt ttccaataaa taagtcaata 19440 aatcactata gaagtaccat ggaaaaaaca taaaagtagc tgtagaatca atagcaggtt 19500 ttaaggtaat ttgaacgagc tttgtacaaa aatacatcaa cagtgccgtg aatgtgccaa 19560 gttattcatc aaagagagcg aaaagtaaaa tgatgcgtcg taaaaaaaat caggtagggc 19620 aagattaact aataaactag gtatttaaaa caaggatcat ccgcccataa accgaaatag 19680 aaaaagagaa catgtttaaa gaaaaaatga aaactataag ggaaataaaa tcttaacaca 19740 taaacgaaaa agtaaggagc cgattatttt gtaaagtata cggccgcaac taaaagaacc 19800 tatagatcgt gactaaacca cttcttccgg agacgtttca ccaggtgagt ctgtccgact 19860 aatggcattc ttcatacggc gtattctgat gaacccaaag gtgtctacta gtaccaagca 19920 ccacccgatt ataatgagaa tagagcctat aagcttctga tgtggtaact cgtcgtaatt 19980 gtattgatcg tcgttattct ccatcccact ctccgaaatc attatgtagc cacgttgaaa 20040 aagagttaaa ctaagtccaa tttgagcacc ataacgaccc aaatgagtcg tcgataagac 20100 atatgtgaca agaaatccta caaaaggaaa gagaatagcg acacaagcac tccatacaaa 20160 ggagaaacca gttccaacgg acatcccatc aatgtaaatc tcgttagatc cgtaatctgg 20220 aattaccata gtggtatccc agtaaggagg ggcggtatcc gcagcagcct gttcataaga 20280 agggggctcc tcttccagtt cttcagtatt agattccact gtgggtttag cagataaatt 20340 agagaagaca ctatcaacgt gatggccatc tgcatgattt gatgaagtgc tgggaattcg 20400 atcattgcta ctacgtacat gcccagagtc gttgccagga tccggcgttg ataaatgttg 20460 gtaaaaagct tcttctcctt ctattgatgc tctggcagag ctatataaag gtgctgtttc 20520 actgtattcc acatcgtcgt ctggaggctc gaaagcagct gccaattccg atcgatttgt 20580 agaccggttt tccggaaatt caggtattgg agtatgaatt gaattttgct aaaatagatt 20640 tgttagactg atatatcagg gaatttaaac agtataaaaa gaaggcttat ccttacattt 20700 gaattagtac tcatgggaat tgtgatatct ttcaacccgt atataatgag gtaaagtgat 20760 taatgaacgt tcccaaaaat ttccgtattt ttgtttttta acccactaaa tgctctttga 20820 ttttaaatta acagagtggt ggaagagtac aggatggatc gaaaccatgg tattattaat 20880 gatcgttact tgcaagtaac aactatattc aaaatctgta gagaaatcag attaaaaaaa 20940 aaatatggga attgagtgtt ttaggtgaca tatcagaagc taaattcccg ttataaatta 21000 tttttgatat ctattctttt caataaacca aacaagccaa ttgaaatcaa tggcttgggt 21060 tataacaatt agtgatcaga tatgtattcc gacaagaagt ggtataaaaa gtcgaaaatg 21120 agaaacaagg aatctcaaag gatttactga tataatcgac ttggtggtaa gatggatgga 21180 tgacatgaat gattagaaag gcgtacgaaa gaatattaaa ttaaaaaaaa aaagcaccaa 21240 cgagtgtatg tcagtaaaag accaagctaa accgttacgt atttttacta atggatgatt 21300 ttggtgcata catatagaat tttaagcgtc aaaaaggtca ctagtgatac gaaaatgtgg 21360 agacgggtca gagcgtgccc aagtaaaatc caaaatagga tgctcatctt tataagaaaa 21420 ggatatctcc tttgattctt caatgacggg cgatgttttg catcgcaggt gcacacgaag 21480 gttggtagaa tggtgaagac gaaactagaa ggcgttagcg atataatcaa tcaaaagaag 21540 ggccagaagg caaagtaaaa tcaaacagta gaaagcatta tcaattttgt ttacacagca 21600 ttgttgtgat ccatactaag aatatgggat ctaaatattg acaacctaat ataatgatag 21660 cagtctctac gtctaactaa tagtttccat caaaaccatc gtctagatgc cttcaaattt 21720 atcaaaaaaa cttacttggt gacacgatac acagattgtt gagtcgttaa tatcagaaag 21780 atggatagaa ccctgaatgg ttgggaaagt aaagttgcat tttgtagcgt tatgtaagtt 21840 cacagatgag cagttggata tggaaatatt gcatgatcgt aaactttttg cggaaacttt 21900 gacagctttg ttgttaggat atggaatgac attatctcca atgttttggt ttttcaaatt 21960 tgccaagtac agggtgtcat tttcaaaata aacttctgga gcttcagcat taactgtaat 22020 attttttacc ggtttctggg acgatttgac gtgcagtgcc cgttgaaagc gaaatggctg 22080 tctgggcaaa atgtcgtgtc gaatttgctg aagccttcgt gtcaaatcta ctagttgttc 22140 catgcatact ctcctgtcat atggtgcaat ttggtcttga acttcattta gctccctcgt 22200 catttcacct aaatattttg acttttcttc aagccaagtc tctttttcgg agcgagaagt 22260 ctgctcacta ggagtggatt tatataattt ggtaagaaat tctacaaaaa agtagttagt 22320 aaatagcaca acaaacagac ctttcgatat gaacgaaatt gcagatgtaa ataaacccat 22380 accttttctc aattcgacga acttttcaga catttttcct tttaaattag aactaaaaca 22440 cccgttatat atgcaaaatt aaatcacagt acgttatgct gtgttcaatg atcattcaat 22500 aaacatatat tttttcaatt ttaacctgca ccaaaagtca ttcaaacagc tcgggaaaaa 22560 aaggattctt aaataaattc atcaaatcag tattagtttt aatcttaact tcgatacttc 22620 gggtgcaaaa attattatga atttttaaaa ttgaaaccaa aaatccaact cttcaaaggc 22680 gaagtacaga agacagtgcc ttgaaatgaa aattatcttc actcaactca aaatgacttt 22740 aagatttgga aataaacgaa gttttgtcga ttttatcgtt atgaatattt ttagcggctc 22800 ttatctttta tcattgagaa tcatcttaaa tttacctgta tgtgagctca acagatgttt 22860 gccttccatt ccttaacaac aacgcccagc agcatttgtt aagtgtgaaa attgaagttt 22920 aactactata ttatcgaaaa tgcctcatga taatattcca tttcctgtta catttgctgc 22980 cggcgcagtt gctggaatct cagaggtaag gttttttatt tggagcactt tatttcattg 23040 aaagatacgt ttgaaggctt tcggagaaga atgttattat cttcaaaatg ctcaatgaat 23100 tgcgtaaggt aaaagagctg tcttggagat gaaggaaagc aaacgtttga ttccgtagat 23160 gctgaacgaa ttacttcttt ataagtttta tcccatgttt tttaaatctc tctttacctc 23220 tcttttacca ttaaaacctt taacatggcc ttgtttacta actctttctt tttcaggtcc 23280 taactttgta tcctttggat gttgttaaaa ctcgtatgca actgtccgtt ggtaaatcag 23340 actacaatgg aacctttgat tgtctcaaaa agatcgtcaa gaatgagggt ccacatcgtt 23400 tgtatcgtgg aattttacct ccaatcttga tggaggctcc taagcgtgca ttaaaatttg 23460 cttccaacga tacttattca aagctgtggc gtaaagtctt caagagaaag gattcaagtc 23520 ctgcactttc tatcctcact ggatcatgtg caggatttac tgaaacgttc gtagtcgtac 23580 ctttcgaact gatgaaaatt cgtttgcaag acgttaagaa tgcttctaag tataacggaa 23640 ctgtcgactg ctttactaaa attgtaaagc aagagagaat tttagctctt tacaatgggt 23700 ttgaagccac tatgtggcgc catgtcgttt ggaatgctgg atattttggt gtaattcaaa 23760 agattcggaa ttcattgacg cctgcctcga gcagaattgg tgaaatccgt aataacctta 23820 ttgctggaac tatcggagga atatttggta cattcctcag cactcccttt gacgttatca 23880 agtcgcgtat tcagacagtt cctcgtattg ccggccaagt tccaaaatat aactgggcct 23940 atccagctct agttacagtc gcaagggaag agggttttac agccctgtat aaaggttttg 24000 tccctaaagt actccgtctg ggccctggtg gtggtattct tttggttgtt tttaattctg 24060 tcatagagtt ttacaagaga tgtcttgtac ataacgcctc tgcttagaga tcaaggtttt 24120 ttttgttttt ctctccccct ttttttggtt cctaaaaaaa tttttttcat tgccgggtct 24180 tcagtaaagg ttgaaagaaa aaagtttcct acgacttgaa ttcgtgggct cttttatcgt 24240 atttagcaat cgctaaatac gtgtatattt gttatcaaaa gttttttggc ttaattttct 24300 cttttttttg tttacattgc atgtatatat tttccatccc tgttaatcat ttcgatgctg 24360 tgttaatcgt taaatttagc aagtctttca tgattgaaga gtacatattg atttaaacat 24420 tgaccttcga aaaaccgttg tgtttttctc ttagatttgc gatcattagt ataagtaatt 24480 atacaacgca atctgtttca acacttttta gaatttttgt tatatgtctt cattccttca 24540 aatgaaaaaa ctcaatcaag catcccagcc atttcggtat atttataata ttatattcta 24600 cgtgattact acagtcgtta tttttaaggt gtgaaaaaca aaatcataga taatgaaata 24660 catttattaa atggactatc cagttgaaga cccagtagta ttttttcgta gctcttttaa 24720 cggttactct tggcaacacg ctcaagctca tccttcttct tgatggcgta agagttggaa 24780 gagcccttag cagcattgat gatttcttca gccaagcatt cagaaatgga cttgacgtta 24840 cggaaagcag cctcacgagc accgatggtg ataagagcaa gagcttggtt gacacgacga 24900 agaggagaaa catcaacggc ttgacgacga acagtaccag cactaccaat acgagtggag 24960 tcttcacgag gaccacaggc agcaacagca tcaaccaaaa cttggagagg gttttggtcg 25020 gtcaagagag caatgatctc aaaagcatgc ttgacaatgc gagtggccaa gagcttctta 25080 ccgttgttac ggccgttcat catcaaactg ttggtcaaac gttcgacaat gaagcagcgg 25140 gccttacgga acctcttggt ctggaaacga ccagcggtgt gagggagagg ttgaccattg 25200 ccaatggtaa tgtaatcact aaataaagtt agaaattctg aaataacatg aaaagttggt 25260 gtaaatgaaa acttttgtaa tttccagctg ctttttccac atttgctcca aggtttaggt 25320 caagtaaaac tagtgaattg actgaaaaaa aaaattacaa cagcatatcc aagtaacgta 25380 ttgtcagcag ttccctttca tgaaaccaag taactacaat tgaatttgta tatttcagac 25440 aattccaagc acaaaatctg gaaagtttac tagcagctag aaaacacaat cccaccttat 25500 acatacacca aagagatatc cttcacttca acaccttcaa aaggaaattt gttgaacaat 25560 ttgatatgtc cagtttcatc caaggaaact tctttaggga tgatagaggc tgccatttct 25620 gtggtggttc agacggtagc ttgtgcaatg tacctactaa acccacacga acatttgtga 25680 ccgttcaata atgaattagg gtagggttta tctgtcgata cttaataatg tttgttatgt 25740 tgaataaagt agtaactgtt gatttaactc aattgtaata aattgtataa ttttttacca 25800 tttaggattt ttagttttat atagaaggcg ctctatgtta tattatcttc acatttctac 25860 tctatatgct ggtatttttg gtcgatcgct gaagcatgca aatcgaggtt aacataatat 25920 tgttttgttt ttattaacta tttgaatact tgtagcatat aagtaatact tcatatacta 25980 gtttg 25985 //