ID SPAC2E1P5 standard; DNA; FUN; 10552 BP. XX AC AL163071; XX SV AL163071.1 XX DT 04-APR-2000 (Rel. 63, Created) DT 04-APR-2000 (Rel. 63, Last updated, Version 1) XX DE 5' end of S.pombe chromosome I cosmid c2E1. XX KW aspartic proteinase; cwg2; DNAJ domain protein; G-beta repeat; KW mannosyl-oligosaccharide 1,2-alpha-mannosidase; KW prenyltransferase and squalene domain (x4); sxa1; KW type i protein geranylgeranyltransferase beta subunit; KW u3 snornp associated WD repeat protein; WD domain; yeast YFR041C. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-10552 RA Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (03-APR-2000) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; P32434; P32434. DR GOA; P32834; P32834. DR GOA; Q9P7C1; Q9P7C1. DR GOA; Q9P7C3; Q9P7C3. DR SPTREMBL; Q9P7C0; Q9P7C0. DR SPTREMBL; Q9P7C1; Q9P7C1. DR SPTREMBL; Q9P7C2; Q9P7C2. DR SPTREMBL; Q9P7C3; Q9P7C3. DR SWISS-PROT; P32434; CWG2_SCHPO. DR SWISS-PROT; P32834; SXA1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c2E1 5' end overlaps cosmid SPAC26A3, EM:Z69240. XX FH Key Location/Qualifiers FH FT source 1..10552 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c2E1" FT /map="IL" FT CDS complement(1..820) FT /db_xref="GOA:Q9P7C3" FT /db_xref="SPTREMBL:Q9P7C3" FT /label=SPAC2E1P5.01c FT /note="SPAC2E1P5.01c, SIMILARITY:Glycine max, AAF16414, FT mannosyl-oligosaccharide 1,2-alpha-mannosidase, (578 aa), FT fasta scores: opt: 633, E():0, (47.1% identity in 227 aa)" FT /partial FT /gene="SPAC2E1P5.01c" FT /product="putative mannosyl-oligosaccharide FT 1,2-alpha-mannosidase" FT /protein_id="CAB86344.1" FT /translation="MVKRRTVKYFLRRILALFVLCVPIYYLYTTVQRPPGYTKLKGSTR FT RKALIKKTFIESWTDYETYGWGKDEYYPIIKRGRNYLRKGMGWMIIDSLDTMMIMGLDE FT QVLRAREWVNNSLTWNQDDEEVSVFETTIRILGGLLSSYHLSQDKLYLDRAVDLADRLL FT AAYNTSTGLPRSNVNLGTRKSRKRTREYFVSTAESGTVQMELRYLSYLTGDPKYWITAD FT KTMEVLLGDATWSHTGLVPITVNLITGAYVGRNIRLGSHGDSYYEYLLKQD" FT CDS complement(1989..2480) FT /db_xref="SPTREMBL:Q9P7C2" FT /label=SPAC2E1P5.02c FT /note="SPAC2E1P5.02c, len:163, SIMILARITY: LOW to FT Schizosaccharomyces pombe, CAB41650, hypothetical 18.8 kd FT protein., (171 aa), fasta scores: opt: 104, E():1.5, (21.5% FT identity in 107 aa)" FT /gene="SPAC2E1P5.02c" FT /product="hypothetical protein" FT /protein_id="CAB86345.1" FT /translation="MMKLENKLHRVLCSLHQNSISTHKTYVAVAAQDEYVRMGKVSLPR FT MYAVKPRIQKNFQDNYRFYGTLLCICWLYFFIWYPFALLALMVGVFLSFVMHGLGSLTI FT NQNIRLDPKYSIPGVCAVTLIVIMFLAPVGRLFWSFCIVSSFAGLHCLLTTYENPAGIL FT " FT CDS 3240..4151 FT /db_xref="GOA:Q9P7C1" FT /db_xref="SPTREMBL:Q9P7C1" FT /label=SPAC2E1P5.03 FT /note="SPAC2E1P5.03, len:303, SIMILARITY:Saccharomyces FT cerevisiae, YFL1_YEAST, hypothetical 34.2 kd protein in FT sap155-ymr31 intergenic regionprecursor., (295 aa), fasta FT scores: opt: 442, E():2e-21, (28.4% identity in 303 aa)" FT /gene="SPAC2E1P5.03" FT /product="DNAJ domain protein; similar to yeast YFR041C" FT /protein_id="CAB86346.1" FT /translation="MSRIFILLLLFGVCLAWTSSDLEIFRVVDSLKSILKNKATFYELL FT EVPTKASIKEINRAYRKKSILYHPDKNPKSKELYTLLGLIVNILRNTETRKRYDYFLKN FT GFPRWKGTGYLYSRYRPGLGAVLVLLFLLISIAHFVMLVISSKRQKKIMQDHIDIARQH FT ESYATSARGSKRIVQVPGGRRIYTVDSITGQVCILDPSSNIEYLVSPDSVASVKISDTF FT FYRLPRFIVWNAFGRWFARAPASSEDTDSDGQMEDEEKSDSVHKSSFSSPSKKEASIKA FT GKRRMKRRANRIPLSKNTNREN" FT misc_feature 3357..3545 FT /note="Match to PF00226 DnaJ, DnaJ domain Score 74.79" FT CDS complement(4282..5349) FT /db_xref="GOA:P32434" FT /db_xref="SWISS-PROT:P32434" FT /label=cwg2 FT /note="SPAC2E1P5.04c, len:355" FT /gene="cwg2" FT /gene="SPAC2E1P5.04c" FT /product="type i protein geranylgeranyltransferase beta FT subunit" FT /protein_id="CAB86347.1" FT /translation="MELTRAKHIAFFKRHLILFPTPYEEHDCERTVLAFFCLLGLDLLN FT ALNTIDDDDKKSWIEWIYKNYVTKESKGIKYSGFQAYRTGIQPISFEQEPQLAGTVFSI FT CCLLFLGDNLSRIDRDLIKNFVELCKTSQGHFRSIAVPSCSDQDMRQLYMATTIASLLD FT FSLSDPLCSIQYIKSCQRYEGGFSLLPYGEAHAGATFCALASWSLILKMIPNSSLNTSN FT QSYNLMDCVPKVERLIRWLASRQLSSGGLNGRTNKDVDTCYAYWVLSSLKLLDALPFID FT GGELEKYLLLHAQHALGGFSKTPGEFPDVLHSALGLYAMAYQDDKSFPKVNADIHMTSK FT YINICRDCIQAAKGK" FT misc_feature complement(4378..4512) FT /note="Match to PF00432 prenyltrans, Prenyltransferase and FT squalene oxidase repeat Score 27.48" FT misc_feature complement(4525..4656) FT /note="Match to PF00432 prenyltrans, Prenyltransferase and FT squalene oxidase repeat Score 59.74" FT misc_feature complement(4723..4833) FT /note="Match to PF00432 prenyltrans, Prenyltransferase and FT squalene oxidase repeat Score 53.14" FT misc_feature complement(4861..5001) FT /note="Match to PF00432 prenyltrans, Prenyltransferase and FT squalene oxidase repeat Score 23.29" FT CDS 5704..7278 FT /codon_start=1 FT /db_xref="SPTREMBL:Q9P7C0" FT /label=SPAC2E1P5.05 FT /note="SPAC2E1P5.05, len:524, SIMILARITY:Homo sapiens, FT O43818, u3 snornp associated 55 kda protein., (475 aa), FT fasta scores: opt: 457, E():6.3e-21, (37.0% identity in 508 FT aa)" FT /partial FT /gene="SPAC2E1P5.05" FT /product="putative u3 snornp associated WD repeat protein" FT /protein_id="CAB86348.1" FT /translation="MSDPFFTRPEHRKRKARSATSKREKENQKLERNGPANEDLASISS FT ESEFNGFEDEIDEENEDTYETAAEKRLRLAREYLDEVKNELVEDGGFDAKEVDRELLAS FT RLKEDVLEKKGQMYLDYTSKINPDVKIETAQLRGRHMRPLVGVVAYENFVYSADKSGLI FT QKWEALQEKDTENRENDDHEIGKAIKLHFRPIKFSRSRRGENDHVKEITCLAISNDGRW FT IVTGGLDHRIVIRDSVTLEPQHCWKHHRDAVMGLAMRRGTNEMFSCSADRSIKVWSLDQ FT MSYIETLFGHQDVIFGVDALARERCVSVGGRDRTSRLWKIVEESQLVFRSGGTSMKATA FT GYMEGSVDCVAMIDEDHFVTGSDNGVIALWSVQRKKPLFTYPLAHGLDPILAPGRHSAE FT TSPDPVTIPPQPRWITSLAAIPYSNLFASGSWDGNIRLWKIAEGLRSFEPLTIATPLSV FT YGCINSLSLSLQGKGKQSEVRVFAACGRETRVGRWKTLRGIPNSGFVFNIPLTVIPSVT FT DGDEIDE" FT misc_feature 6940..7020 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 31.38" FT misc_feature 8035..8146 FT /note="Small fragment with similarity to the active site of FT tf2 type transposon" FT CDS 9011..10552 FT /db_xref="GOA:P32834" FT /db_xref="SWISS-PROT:P32834" FT /label=sxa1 FT /note="SPAC2E1P5.06, len:513" FT /partial FT /gene="sxa1" FT /gene="SPAC2E1P5.06" FT /gene="SPAC26A3.01" FT /product="aspartic proteinase sxa1 precursor" FT /protein_id="CAB86349.1" FT /translation="MKASFFVFAISALQALQASVASAYSEVPGKRSVVLNLQHSQYDHV FT ARKLERTKVLNKRDSSGYPVLDLEYTDAGGYFANLTLGSNERVYSLTLDTGSPYTWVTA FT KNITALSASEIWSDTDGVDAGRSTSDIRTNACTNYTCFDYSSTTARRTNSSTIGFLASY FT GDNTTVLGYNMVDNAYFAGLTLPGFEFGLATREYDSSQISVTPGIIGLSVAMTITGISS FT DDKVVAFTPPTIVDQLVSANVIDTPAFGIYLNEDVGELIFGGYDKAKINGSVHWVNISS FT SDDSTFYSVNLESITVTNSTSSNNVQSSKRSSKDIEVNTTVTLDTGTVYIYLPEDTVES FT IADQYQGIVSEYGYVVIYCDSFSDSDYISFNFGSDADFHVSVNDLVIYRQESTSGDICY FT LALFEGDTSSYLLGQYFLQYVYSIYDWDAQKIGLAALNSNATSTANHQILNINSALRSV FT TSGQSVSATPTVSMSIAATSFGSSLVLTASASPSSTSVDGSSSSDSSEASGAASVG" FT misc_feature 9206..10318 FT /note="Match to PF00026 asp, Eukaryotic aspartyl protease FT Score 494.36" FT misc_feature 10449..10552 FT /note="Nominal overlap with SPAC26A3, EM:Z69240 S. pombe FT chromosome 1" XX SQ Sequence 10552 BP; 3361 A; 1927 C; 1994 G; 3270 T; 0 other; gatcttgttt cagtaaatac tcatagtagg aatcaccgtg agaacccagt cgaatatttc 60 gaccaacgta ggcgcctgta atcaaattta ccgtaatagg aaccaagcca gtatgagacc 120 aagtagcatc tcctagcaac acctccattg tcttgtcagc cgttatccaa tatttaggat 180 cgccagtaag ataggataaa taacgtagct ccatctgaac agttccggat tcagcagtgc 240 ttacgaaata ctctctagtt ctttttctag atttacgagt tcctaggttt acatttgatc 300 taggtaagcc cgtggaggta ttataagcag ctagcaaacg atcagctagg tccactgcgc 360 ggtctaggta tagtttgtct tgagacaagt gataagaaga aaggagtcct cccaatatac 420 gaatagtagt ttcaaaaaca ctaacttctt cgtcatcttg gttccaagta agagaattat 480 taacccattc acgagcacgt aaaacttgtt catcaaggcc cataatcatc attgtatcaa 540 gggaatcaat aatcatccag cccatgccct tcctaaggta attccgtcca cgtttaataa 600 taggatagta ttcatcttta ccccagccat aagtttcata gtctgtccag ctttctatga 660 atgttttctt aatcagcgct tttcttctcg tggagccttt aagtttggta taaccaggag 720 gtcgttggac agtcgtgtat aaataatata ttggaacgca taatacaaag agtgccaaaa 780 ttcgacgaag aaagtatttg acagtccttc gtttaaccat tattaaaaaa aatagaaaga 840 ataagaaatt taaaatcgat ataatataat aaaataacag gataagttaa ccacaatatt 900 taagcatcag aacttgtgaa ttaaatgact gcggtcaaga aaacaatcag ttttttctca 960 aattttcaaa agttttgaca aggggtaaat gataaaatcg aagttctttc aaatctacct 1020 gttttccgtc aaaatcgaag cttgcacaca aatataaaga taatcgttca caagaatgtt 1080 cagtcagaaa atgaacataa ttttacttaa tgaattagct atatttttac gtattcgctt 1140 atcaagatct aaaaaccgat cttgaattag caaagaagca gtagttggca gaggttagcg 1200 aatccatgcc agtaatacaa aagtgcattc ttgtgaatca accctaacca tcaaacaaaa 1260 catctaaatc gaagtttgta aaaatatcta aaattaaatt ttcttttttt acttattcgt 1320 acaataagag cttctcaacc tttggtctac gtatgtttgt ttgtctatgt agattcctca 1380 gatgtcaatc taaaaattcc caaatattct caatcctgaa cttctgggta gacattatat 1440 aacctatgaa ttaaacaaaa gtgcttgttg attttcaatt atgaccatcg cattctaaaa 1500 tctacaggtt cgaagctcga aataatcatt aaaacttaag cattttttaa agatgtactt 1560 attctataat ccatttagtg acttaaactt gaagcattgg tagaagaata aggctgctca 1620 cctacgtgtt tatgtgtaaa ttgatttaac tatgttgatt gcatgctcaa aacactcctt 1680 ctgaaaaaga actatttaca aatacgtata tatagtcctt gggaaaaaat ataacatttt 1740 tatcgtttct tccagcttac acctacaatg ttaagtaggg tatcagtgct gattaaaagc 1800 tgaaacctcg atacgtttta tcaacttctt gtttcccgta aagaaaatgc tcaaagttta 1860 agtagatgat cgtagaaaaa cttataaagg aatgagtgaa gaaaagcatc ctgtggattt 1920 gcacagcatt aagtctaacg gcttacagtg aattttgtat tcataaaaag taggcacttg 1980 gtggaaaatc acaatatacc cgctggattc tcataagtag tcaataaaca atgtaaccca 2040 gcaaagcttg acacgataca gaatgaccaa aacaaccgtc ctactggagc gagaaacata 2100 ataacgatca gagtgacagc acaaacacca gggatggaat acttgggatc taatcttata 2160 ttttgattaa tggtcaagct tcccaagcca tgcataacaa aacttagaaa aacaccaacc 2220 attagagcta acaaagcaaa tgggtaccag atgaagaaat aaagccagca aatacaaagc 2280 aaagttccat agaatctata attgtcttga aaattctttt gtattctggg tttaacagca 2340 tacatacgag gtaaagagac ctttcccatt cgtacatatt catcttgcgc tgctaccgca 2400 acatatgttt tatgagtgga tatggaattc tggtgcaatg aacatagcac tcggtgtaat 2460 ttattttcta acttcatcat caggaagatt gatgtgtgga aatgggaaac gttttggctc 2520 ctccagtaat ggcgcccatc gatggtttgt ttacattctc taatcgctac cgtaaacaac 2580 ttttcgtaga ttcaattcac attaatcaaa atcatatgaa aaaacataag gtaaatataa 2640 tagtatggtc gcaaacaaaa tttgttcaaa ataatttgaa accatttact cttcaaggat 2700 aactagtcca ccggtgccta attgcaggta ttcgaaatgc aaaacaaaaa ttagaaattt 2760 cagagaaata tgaacaaaaa aataattaag agagaattac aagctgtact ggcgtcgccg 2820 gatctggttc ctatttgccc atcaccacca acgctttcat agtctgtatc tagaaataaa 2880 acacgagaaa cgtgttagca taataatttt tctgttaaaa catagctacg ctagtgccat 2940 ttcccgtcaa tgttaagttc tttcaaaaaa tcgttccata aaatttcttg agcaactttg 3000 gttgtacctt tcctcacaca agagagcgta atttcataga cggaaataaa aaaaagaaaa 3060 aaaataataa aattataaat acccttaaaa tcgtaatttt tttcttaccc aaccttgttt 3120 taataccagc cttcgaaaga taaaaatact gatacttcgt tattcagcgt ttgtttaaat 3180 aggttagcga acgcgtatca cccaagaacc taaccttcgg gttgcaaaat agagcggaaa 3240 tgagcagaat ttttatttta ctgcttttat ttggagtctg cttagcgtgg acctcttccg 3300 accttgaaat ttttcgagtt gttgattctt taaagtcaat tttgaagaat aaggccacgt 3360 tttatgagct actcgaagtg cctacaaaag cctctattaa agaaatcaat agagcgtaca 3420 gaaagaagag catcctttat catccagata agaatccaaa aagtaaagaa ttgtatacgc 3480 ttttagggct gatcgtaaac attcttcgca acactgaaac gcgtaaacgt tatgactatt 3540 tccttaaaaa tggatttcca agatggaagg gaacgggtta tctttattca agatatcgcc 3600 ctggtttagg tgctgtgctc gtcttgttgt ttcttctcat ttccatcgca cacttcgtta 3660 tgctcgtaat cagttcaaag cggcaaaaga aaatcatgca ggatcatata gacattgcta 3720 gacaacacga gtcttatgca acttccgcca gaggttcaaa gcgtattgta caagtacccg 3780 gtggaaggcg tatatataca gtcgattcca taactggtca agtgtgtatt ttggatccca 3840 gttccaatat agaatatcta gtttcaccag attccgttgc aagcgttaaa atatctgaca 3900 cctttttcta ccgtcttccc cgatttatag tttggaacgc ctttggacgc tggtttgcaa 3960 gagcacctgc atcgtccgaa gatacggata gtgatggaca gatggaagat gaagagaaaa 4020 gtgatagtgt ccataaatct agcttctcca gtccttcgaa gaaagaggct tccataaaag 4080 ccggaaagcg acgaatgaaa agacgagcaa atcgaattcc actttctaaa aacacgaata 4140 gagaaaatta aagttactga gtcaaattta tattgttaga gtgtctttag gtttttatag 4200 tcaagtgatt gatcacgttg tttctaagtt aatagtctat tgtttagttt tcttcgacaa 4260 ttcatcatca taatatagtt atcatttccc cttggctgct tgaatacagt ctctacaaat 4320 gtttatatac ttggaagtca tatgtatatc tgcatttact ttaggaaaag acttatcatc 4380 ttgataagcc attgcatata gaccaagtgc agaatgtaaa acatcaggaa actcacctgg 4440 tgttttagaa aatccgccca aagcatgttg agcatgcaat aataaatatt tttccaactc 4500 acccccatcg ataaaaggca gagcatcaag gagttttaat gaactcaaaa cccaataagc 4560 ataacaggtg tcaacgtctt tattcgtcct tccgtttaat cctccagatg ataattgtct 4620 agaagctaac catctgataa ggcgttctac tttaggcaca caatccatta agttatatga 4680 ttgattagaa gtattcaaag aggaatttgg aatcattttc aatattaaag accatgatgc 4740 taacgcgcaa aatgtagctc cagcatgggc ttcgccgtat ggtaacaaag aaaatccgcc 4800 ttcatagcgt tgacagcttt taatatattg gatagaacat aaagggtcag acagagagaa 4860 atcaagaagc gaagcaatag tcgtagccat atataactgt cgcatgtctt ggtccgaaca 4920 tgatggcaca gcaatacttc taaaatgacc ctgcgaagtt ttgcacaact ccacaaaatt 4980 cttaattaaa tcgcggtcga tacgagaaag attatcgcca agaaataaaa ggcaacaaat 5040 tgaaaacaca gtcccagcta attgcggctc ctgttcgaat gagatgggtt gaatgccagt 5100 tctatacgcc tgaaaaccgg agtatttgat tcctttagat tctttcgtta catagttttt 5160 gtagatccac tcgatccaac tttttttatc gtcatcatct atggtgttca atgcatttag 5220 caagtctaat cctaataaac aaaagaatgc taacactgtt ctttcgcaat cgtgttcttc 5280 gtatggagta ggaaatagta taagatgtct cttaaagaaa gcaatatgtt tagctcttgt 5340 taattccatt ggaccataaa tagatgcgcc gatagcagaa ttctatagat gtcaatagaa 5400 tagtaagtct taaaaatcta tcgaacaaaa ttggtacaag aacgataatt attttaagct 5460 taaaaacaaa aaaacgcgac aaggtatttt gatttatagt aatgagcaga tatatttctg 5520 taatgatttg ttcatgaaaa gaaattcggt gaattagctc ggtaaacttc ggaaatttct 5580 tgtatggatc accggacttt ttgtggagta tgctcggaga ataaaattaa gtcaccggca 5640 gtataccata taggtgtttg aagatacaga aatttacgaa ccgttggtac ccttagagaa 5700 agcatgtctg atcctttctt tacacgtcca gagcatagaa agaggaaagc taggagtgct 5760 acttcaaaaa gagaaaaaga gaatcaaaaa ttggagagga atggacccgc taatgaagat 5820 ttagcatcta tatcatcaga atccgaattc aatggctttg aggacgaaat tgatgaggaa 5880 aatgaagata cttatgagac tgcagcagaa aaaaggcttc gattagcaag ggagtatcta 5940 gacgaggtca agaacgaact ggtcgaagat ggaggtttcg atgcgaaaga agtggatcgt 6000 gaattgcttg caagtcgatt gaaggaggac gtattagaaa agaagggaca aatgtattta 6060 gactatactt ctaaaattaa tcctgatgta aaaatcgaaa cagctcagct gcgaggccgt 6120 cacatgcgtc cgctagttgg agtggtagca tacgaaaatt ttgtttatag tgctgataaa 6180 tcgggtttga tccaaaaatg ggaagctttg caagaaaaag atactgaaaa tagggaaaat 6240 gacgatcatg aaattgggaa agctataaaa ttgcacttca gaccgatcaa attctctcgc 6300 agccgaagag gagagaacga tcatgtaaaa gaaatcactt gcctagcaat tagcaacgat 6360 ggtcgttgga tcgttactgg aggtttggac catcgaattg tcattcgtga tagtgtgaca 6420 cttgagcctc aacattgttg gaaacatcat cgggacgcag taatgggatt agccatgcga 6480 agaggaacca atgaaatgtt tagttgttcc gctgatcgat ccatcaaggt atggtctttg 6540 gatcaaatgt cttatattga aacgctattt ggacatcagg atgttatttt tggagtggat 6600 gcattagctc gggaaagatg tgtcagtgta ggtggtagag atcggacatc gcgtctgtgg 6660 aaaattgttg aggagtctca actggtattt cgtagtggag gtacttctat gaaagcaact 6720 gcaggctata tggaaggtag tgtggattgt gtggcaatga ttgatgaaga ccatttcgtt 6780 actggaagcg ataatggagt tattgcactt tggtctgttc aacgtaagaa gcctcttttt 6840 acatacccac ttgctcatgg actagatccc attctagctc ctgggcgtca ttccgctgag 6900 acgtctccag atcctgtcac tatacctcct caacctcgat ggatcactag tttggctgct 6960 atcccatact ccaatctatt tgcttctggt tcttgggacg gaaacatccg tttatggaag 7020 atagcggaag gccttcgttc ttttgaacct ttaacaatcg ctactccgtt gtcagtttat 7080 ggctgcatca attccctttc actttctttg caaggaaaag gtaaacaatc agaggtaaga 7140 gtattcgctg cttgcggaag agaaactcgc gttggtcgtt ggaaaacctt gcggggcatc 7200 cctaattcag gcttcgtgtt taatatccct ttaacggtta ttccttctgt tacagatggt 7260 gacgagattg atgagtagta aagttgcaaa ataaaagaac ttagcttttc attatttttc 7320 atataagcgg ttatgaagca gatgtgatgg atctcttatt actgtgttta tcttttcctg 7380 gtgtacaaaa aattttaatt catggaacgg aattttgggt tggatttaat ttaaaagttt 7440 agataaaata cggatttatt aggaaaaaat atacaaaaat gaaattgatt attaaaacga 7500 acaatgatga accatgtctt tcaattcggg cttttctatt tgggttcttt aaatgtttta 7560 taaattgaaa aaagaaaaag aaggatgaaa tagtttgtaa taaacgaatg aactttcttc 7620 ttcatcaaat gccgtgcatt gaaatggtgc ataatgaaat tattgaagca aaatgaaaat 7680 atcaaaatcg ttaaaccgaa gttttgttta tgagtattgt taaaatccta ttaagtttta 7740 ctagttcttg ctatcacttt gtttacctct tgccccaaat tgtcctcaat attacttgtc 7800 ttaataatgg taatcaaaag cccttttttt agtttttagt atcttataga ttctttaatg 7860 gagtatagac cttttaaaaa agtcgttctt tggaattctc ctagactcgt caaaaatgaa 7920 atacatgtat ctttgcatga aaagttgatg gacttagcaa aaagcgcata ttggcataat 7980 actctatttt ttaatttgga atgaattttc tttaacaaat gacagaacct agaatcgtaa 8040 atatttaaga ttcctaggtt gtttccactt tataacttcg actgtacttt cttgacaaac 8100 caaaaaacgg ttttttaata tactaatatc actaaatggt acttatttgc tcccgcaact 8160 acggttatct ttggttttcc aaatcccgtt accgtgacac tttgcagata tggtggtaat 8220 atattttaat aaagatataa acaccatgac tactatgaat cacgagatgc ggtagccgtt 8280 aaatcaatgt ttttatacag aaactttgtc aaacgaaact attgatccgt cgaacatgcg 8340 gtctttttgt gcagtattac ttaacacaac ttttcacagt agccgttatc tatctatgta 8400 gaattctcct aatataactt gacgttttta tctcaggcgc ttagataaca tgtgcttatt 8460 ttcttcatct ttgcagctag ctacactgta tatatatggg tcttcatcgg agtttcgaca 8520 gacattcaca taaatggaga ggcaaatcaa ttactagcaa gcgaacaaat taacagttta 8580 agtaatcaaa ttgtacaatg ttttcaagta atttccggta aaatgcttac attgattttt 8640 attttaatgg aaacactttg gaatacgtta tgtgcattaa gctactacgc tacaatacct 8700 ttataatgta taatgaattt ttaacgttgc aaaagggatt tcctttggat atgaaaggat 8760 tataacgaag tttgctgtta aaagaaaata cgaaaaagtc atttaacgag ttcggttcat 8820 gaatgcgtca actaagccgc gaatggctta aaccgcggat tacgttgatg tgaaattctg 8880 gggggcacat actttgacca gagcaaacta cattaaagca ggcggaaacg catacaccgt 8940 ctattagttt ggaagaaaac caaagcttgt tgttgctctg attaataaca tttctaatca 9000 atataataat atgaaggctt ctttctttgt atttgcaatt tctgctttgc aggcgttaca 9060 agcctcggta gcttctgctt atagcgaagt tccaggaaaa cgatcggtcg ttttaaatct 9120 gcaacatagc caatatgatc atgtggcgag gaaactggaa cgtaccaaag tactgaacaa 9180 gcgcgattct tcgggatatc cagtgttgga tcttgagtac actgatgctg gcggttattt 9240 cgctaacctt accttgggca gcaatgaaag agtctattct ctcactttgg atactggtag 9300 tccttatact tgggttactg ctaagaacat tacggcctta agtgcttccg agatttggag 9360 tgacaccgat ggggtggatg ctggtagatc tacctcggac attcgtacta atgcttgtac 9420 caactacacg tgttttgatt attccagcac taccgccagg cgtaccaact ccagcaccat 9480 tggatttttg gcttcctatg gcgacaacac caccgtcctt ggctacaata tggtggataa 9540 cgcttatttc gccggtctta ccctacctgg ctttgaattt ggattggcta cacgcgaata 9600 tgatagtagt caaatttccg taacgccggg aattatcggt ttgtcagttg ccatgactat 9660 tactggtatt agttctgatg acaaggtcgt tgcttttact ccccctacca ttgttgatca 9720 attggtaagc gcaaatgtga tcgacacccc cgcgtttgga atttatttga atgaagatgt 9780 tggtgaactt atttttggtg gttatgataa ggcaaaaatc aatggatctg ttcactgggt 9840 caacatctct tcctctgatg acagcacctt ttattccgtt aatctcgaaa gtatcactgt 9900 taccaattct acctccagta acaatgttca aagctccaaa cgctcctcta aagacattga 9960 ggtcaacacc actgtcactt tggatactgg tactgtttat atttatttac ctgaggatac 10020 tgttgagtcc atcgccgatc aataccaagg tattgtaagt gagtatggtt atgttgttat 10080 ttattgcgac tctttctcag attctgatta catttctttt aactttggca gcgatgccga 10140 ctttcatgtt tccgttaatg atttggtcat ttatcgtcaa gaatccactt ctggtgatat 10200 ttgctatctt gctttgtttg aaggtgacac ctcgagttac cttttgggtc aatacttctt 10260 acaatacgtt tattctattt atgattggga tgcacaaaag attggtcttg ctgctttaaa 10320 tagtaacgca accagtactg ccaatcatca aattttgaac attaactctg ctttgcgtag 10380 cgtcactagc ggtcagagcg tttctgctac tcctacagtt agcatgtcga tcgctgctac 10440 ttctttcgga tcttccctcg tacttactgc ttccgccagt ccttcctcca cttctgttga 10500 tggcagcagc tcttcggatt ctagtgaagc atctggagcc gctagtgttg gc 10552 //