ID SPAC2E1P3 standard; DNA; FUN; 13297 BP. XX AC AL162531; XX SV AL162531.1 XX DT 28-MAR-2000 (Rel. 63, Created) DT 28-MAR-2000 (Rel. 63, Last updated, Version 1) XX DE 3' end of S.pombe chromosome I cosmid c2E1. XX KW ammonium transporter; Ammonium Transporter Family domain; KW cellulose binding beta glucosidase; peroxisomal copper amine oxidase; KW putative dehydrogenase; repeat (at)12; retrotransposble element; KW tf2 type transposon; tf2-10. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-13297 RA Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (28-MAR-2000) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; Q05654; Q05654. DR GOA; Q9P7F1; Q9P7F1. DR GOA; Q9P7F2; Q9P7F2. DR GOA; Q9P7F3; Q9P7F3. DR GOA; Q9P7F4; Q9P7F4. DR SPTREMBL; Q9P7F1; Q9P7F1. DR SPTREMBL; Q9P7F2; Q9P7F2. DR SPTREMBL; Q9P7F3; Q9P7F3. DR SPTREMBL; Q9P7F4; Q9P7F4. DR SWISS-PROT; Q05654; RT21_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c2E1P3' is overlapped at its 3' end by cosmid SPAC513, CC EM:AL122032. XX FH Key Location/Qualifiers FH FT source 1..13297 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c2E1" FT /map="IL" FT misc_feature 1..104 FT /note="nominal overlap with cosmid SPAC513, EM:AL122032 S. FT pombe chromosome 1" FT CDS 183..1229 FT /db_xref="GOA:Q9P7F4" FT /db_xref="SPTREMBL:Q9P7F4" FT /label=SPAC2E1P3.01 FT /note="SPAC2E1P3.01, len:349, SIMILARITY:Cochliobolus FT carbonum, TOXD_COCCA, toxd protein., (297 aa), fasta FT scores: opt: 444, E():5.5e-21, (32.0% identity in 244 aa)" FT /gene="SPAC2E1P3.01" FT /product="putative dehydrogenase by similarity" FT /protein_id="CAB83005.1" FT /translation="MKAVIADGQNGVEVISDAPKPTPEKGEFLGRVIRVAFNPIDWKTL FT YNASIEKGTVGGTDFVAVVEDVGEGVDRSKYIGATVSGWAPGPLDGSNAAWREYITLDV FT NLVYFVPKNITPSQAATLPLTFTTASQGLNQYLGLPLPPTDGSKNSAQQKWVLVWSGSS FT SVGQYVVQLAHHAGYKVIATCSPHNFDWIKKLGADFTVDYHDPNVVEIIKKATDDSVFY FT GFDAASFPETSTLAVKAFSSKVKDGKLINILSSPPSPRSEVKIIGIIDYSLFNREFNFF FT GNKIEPIQASYDHAVEVYKKLTGWLQEGVIIPNRVKEFDGGLQAIPKALREFASGKHSA FT VKFVVRID" FT CDS complement(1754..3307) FT /db_xref="GOA:Q9P7F3" FT /db_xref="SPTREMBL:Q9P7F3" FT /label=SPAC2E1P3.02c FT /note="SPAC2E1P3.02c, len:482, SIMILARITY:Saccharomyces FT cerevisiae, MEP2_YEAST, ammonium transporter mep2., (499 FT aa), fasta scores: opt: 1121, E():0, (39.6% identity in 432 FT aa)" FT /note="possible splice 2531,2640 but inframe and no FT consensus branch" FT /gene="SPAC2E1P3.02c" FT /product="ammonium transporter" FT /protein_id="CAB83006.1" FT /translation="MLNEPNALLRRDANSTIATVTELFPNEYSNADIAYVLLSTVVVFT FT VTPGIALYYAGMVRKNSALSILTQSFLVTAVVFIQWYLFGYSLACSSGSSFYGTLWQGG FT MNHLWLEPYIPGSTIPAIVYFPFGGLFAVATAQLFAGAMAERGRLIPSLVISFLYITLV FT YCPQAYWTWAPNGWLYTLGALDFAGGGPVHISSGFAALAYSLCLGRRIVVDEPDRPDSI FT RSTDNADLPSSSQNNCKANWKRWFGFKSVSWKNSFGRGKIAHNPPHDAGMVYIGVVLIW FT FAWLCFNSGTLLTVNIRTAYIMTNTLISSSFGALTWAIIDYIRYRKFSTIGICEGAIAG FT LVGITPACGFVFPWGAAAGGIVPALVCNFLHDLNEWIGVDETLRVFNLHGIGGIVGSIV FT LGVVAHPDVAASDGATVIDGGWAVHHWKQMGYQFAGFTSVAAWSFVITAIICLLVDLVP FT GLHIRASFEEELRGMDFVELEEQLPGQTLESKPMIIYAQEMDEPVTQGSNIKQEKQDEF FT " FT misc_feature join(complement(2640..3205),complement(1868..2531)) FT /note="Match to PF00909 Ammonium_transp, Ammonium FT Transporter Family Score 427.67" FT misc_feature complement(2081..2110) FT /note="PS00758 ArgE / dapE / ACY1 / CPG2 / yscS family FT signature 1" FT LTR complement(3666..4014) FT /note="Tf2-type LTR" FT CDS complement(4065..8066) FT /db_xref="GOA:Q05654" FT /db_xref="SWISS-PROT:Q05654" FT /label=tf2-10 FT /note="SPAC2E1P3.03c, len:1334" FT /gene="tf2-10" FT /gene="SPAC2E1P3.03c" FT /product="retrotransposble element; tf2 type transposon" FT /protein_id="CAB83007.1" FT /translation="MSYANYRYMKARAKRWRPENLDGIQTSDEHLINLFAKILSKHVPE FT IGKFDPNKDVESYISKLDQHFTEYPSLFPNEHTKRQYTLNHLEELEQQFAERMFSENGS FT LTWQELLRQTGKVQGSNKGDRLTKTFEGFRNQLDKVQFIRKLMSKANVDDFHTRLFILW FT MLPYSLRKLKERNYWKSEISEIYDFLEDKRTASYGKTHKRFQPQNKNLGKESLSKKNNT FT TNSRNLRKTNVSRIEYSSNKFLNHTRKRYEMVLQAELPDFKCSIPCLIDTGAQANIITE FT ETVRAHKLPTRPWSKSVIYGGVYPNKINRKTIKLNISLNGISIKTEFLVVKKFSHPAAI FT SFTTLYDNNIEISSSKHTLSQMNKVSNIVKEPELPDIYKEFKDITAETNTEKLPKPIKG FT LEFEVELTQENYRLPIRNYPLPPGKMQAMNDEINQGLKSGIIRESKAINACPVMFVPKK FT EGTLRMVVDYKPLNKYVKPNIYPLPLIEQLLAKIQGSTIFTKLDLKSAYHLIRVRKGDE FT HKLAFRCPRGVFEYLVMPYGISTAPAHFQYFINTILGEAKESHVVCYMDDILIHSKSES FT EHVKHVKDVLQKLKNANLIINQAKCEFHQSQVKFIGYHISEKGFTPCQENIDKVLQWKQ FT PKNRKELRQFLGSVNYLRKFIPKTSQLTHPLNNLLKKDVRWKWTPTQTQAIENIKQCLV FT SPPVLRHFDFSKKILLETDASDVAVGAVLSQKHDDDKYYPVGYYSAKMSKAQLNYSVSD FT KEMLAIIKSLKHWRHYLESTIEPFKILTDHRNLIGRITNESEPENKRLARWQLFLQDFN FT FEINYRPGSANHIADALSRIVDETEPIPKDSEDNSINFVNQISITDDFKNQVVTEYTND FT TKLLNLLNNEDKRVEENIQLKDGLLINSKDQILLPNDTQLTRTIIKKYHEEGKLIHPGI FT ELLTNIILRRFTWKGIRKQIQEYVQNCHTCQINKSRNHKPYGPLQPIPPSERPWESLSM FT DFITALPESSGYNALFVVVDRFSKMAILVPCTKSITAEQTARMFDQRVIAYFGNPKEII FT ADNDHIFTSQTWKDFAHKYNFVMKFSLPYRPQTDGQTERTNQTVEKLLRCVCSTHPNTW FT VDHISLVQQSYNNAIHSATQMTPFEIVHRYSPALSPLELPSFSDKTDENSQETIQVFQT FT VKEHLNTNNIKMKKYFDMKIQEIEEFQPGDLVMVKRTKTGFLHKSNKLAPSFAGPFYVL FT QKSGPNNYELDLPDSIKHMFSSTFHVSHLEKYRHNSELNYATIDESDIGTILHILEHKN FT REQVLYLNVKYISNLNPSTIMSGWTTLATALQADKAIVNDYIKNNNLNI" FT misc_feature complement(6222..6761) FT /note="Match to PF00078 rvt, Reverse transcriptase FT (RNA-dependent DNA polymerase) Score 154.96" FT LTR complement(8233..8581) FT /note="Tf2-type LTR" FT repeat_region 9603..9626 FT /label={at}12 FT /note="(at)12" FT CDS 9658..11796 FT /db_xref="GOA:Q9P7F2" FT /db_xref="SPTREMBL:Q9P7F2" FT /label=SPAC2E1P3.04 FT /note="SPAC2E1P3.04, len:713, SIMILARITY:Pichia angusta, FT AMO_PICAN, peroxisomal copper amine oxidase, (692 aa), FT fasta scores: opt: 2852, E():0, (58.5% identity in 691 aa)" FT /gene="SPAC2E1P3.04" FT /product="peroxisomal copper amine oxidase" FT /protein_id="CAB83008.1" FT /translation="MAYYPHLPYHHHHHTSVPGERLSDPLDPLSADELKLAVEIIRHEY FT PSKHFAFNVVTLEEPPKAKYLHWKYSKEDAHKPERIALAVLLEKGVPGILEARVNLTKA FT EVIQIEHITGVCPILTADMLVNTEQIVRKDPAVIEQCILSGVPPDQMDHVYCDPWTIGY FT DERYGNTRRMQQAMMYYRSNEDDSQYSHPLDFCPIIDTEDQKVVAIDIPPVRRPLSKHK FT HSNFNKKDIEAELGKMREVKPISVTQPEGVNFRMKGRYIEWQNFRMHIGFNYREGIVLS FT DISYNDNGHIRPLFYRMSIAEMVVPYGNPEHPHQRKHAFDLGEYGAGYLTNPLALGCDC FT KGVIHYLDAHFVNNTGEVETVKNAICIHEEDDGVLFKHSDFRDKFRTTISARGIRLVIS FT QIFTAANYEYMVYWIFHMDGVIECELKLTGILNTYAMNEGEDLKGWGTQVYPQVNAHNH FT QHLFCLRLNPMLDGYSNSVAVVDGVSGPGEPGSKENYYGNAFTTERTVPKTVKEAICDY FT NSDTSRTWDICNPNKLHPYSGKPVSYKLVSRETPRLMARPGSLVSNRAGFARHHIHVTP FT YKDGQIYPAGDYVPQTSGEPTKGLPEWIAEEPDASVDNTDIVVWHTFGITHFPAPEDFP FT LMPAEPIRLLLRPRNFFLRNPALDVPPSKNVTTSEVKQAHHHGNLHMMDMMKSLTDATS FT EFAFGEKFCEKHKGDHFF" FT misc_feature 9691..11652 FT /note="Match to PF01179 Cu_amine_oxid, Copper amine oxidase FT Score 867.50" FT misc_feature 10843..10884 FT /note="PS01164 Copper amine oxidase topaquinone signature" FT misc_feature 11521..11562 FT /note="PS01165 Copper amine oxidase copper-binding site FT signature" FT CDS complement(12371..12964) FT /db_xref="GOA:Q9P7F1" FT /db_xref="SPTREMBL:Q9P7F1" FT /label=SPAC2E1P3.05c FT /note="SPAC2E1P3.05c, len:198, SIMILARITY:Porphyra FT purpurea., PSBP_PORPU, putative polysaccharide binding FT protein precursor., (210 aa), fasta scores: opt: 301, FT E():9.5e-09, (39.1% identity in 115 aa)" FT /gene="SPAC2E1P3.05c" FT /product="putative cellulose binding beta glucosidase" FT /protein_id="CAB83009.1" FT /translation="MLTQSLFLTVLTLALSLVSKTSASQCSPRYGTCGGIYYDGPTCCV FT VGSSCIYSNPWYSQCIPVDYTGPCAKLYQQCGGINYNGPTCCEPGSECIYNGPYYSQCI FT PVDIDPSSSSSSAASSTTSTTSSSSLVSSTTLTSSSPSAVSSTTSIPSISSTISSSVST FT SSFTSLSSSGFSTVLSSTNTTSALPSSGWNVTGY" FT misc_feature complement(12665..12748) FT /note="Match to PF00734 CBD_1, Fungal cellulose binding FT domain Score 54.95" FT misc_feature complement(12794..12880) FT /note="Match to PF00734 CBD_1, Fungal cellulose binding FT domain Score 52.86" XX SQ Sequence 13297 BP; 3999 A; 2402 C; 2538 G; 4358 T; 0 other; ttacataatg ccctcgtaaa tgaaatatat attcggcctc gaactcttct ataatctttt 60 aattttcttg gtctaccttt ttgtcaaaat tcgaagtact gatcgggaaa gttggtaact 120 ctcttttttt atttctacta agtctaaaaa tttaacgaat ttaaattaaa atcgtataaa 180 acatgaaggc agtgatagca gatggtcaaa acggcgtaga ggttatatca gatgccccta 240 aaccaactcc tgaaaagggc gagtttttag gtcgagttat tcgtgtcgcg ttcaatccta 300 tcgattggaa aacactctac aatgcgtcga ttgaaaaagg caccgttggc ggaaccgact 360 tcgtggctgt tgtggaagat gttggagaag gcgtcgacag atcgaaatat atcggtgcca 420 ctgttagtgg gtgggctcct ggtcctttag acggttctaa tgctgcttgg cgtgaataca 480 tcactcttga tgtaaatttg gtgtactttg ttcccaagaa tattacacct tcacaagccg 540 ctacgcttcc tctaacgttt actactgctt cgcaaggact taatcagtac cttggtcttc 600 ccttgcctcc cacggatgga tccaagaatt ccgctcaaca aaaatgggtt ttagtatgga 660 gcgggtcatc tagcgtaggg caatacgtgg ttcaacttgc gcatcacgct ggttataagg 720 taattgctac ttgttcgcct cataactttg actggattaa gaagctaggt gccgatttca 780 cggttgatta ccatgatcct aacgtggtgg agattattaa aaaagcaact gatgactctg 840 tcttttatgg atttgatgcc gccagcttcc ctgaaactag tacattagcg gttaaggcat 900 ttagctcaaa ggtaaaagat ggtaaactca tcaacatttt atcttcaccc ccttcaccta 960 ggtctgaagt aaaaatcatt ggaatcattg attattcact tttcaaccgg gagttcaact 1020 tctttggtaa caagatagaa ccaattcaag ctagctatga tcatgctgtt gaagtataca 1080 agaaattgac tggctggctc caggaaggag taatcatccc taatcgtgta aaagaatttg 1140 atggtggatt gcaagctatt cctaaggctt tacgtgagtt tgcctcaggg aagcacagtg 1200 ccgtaaagtt tgtggttcgc attgactaaa acggcacttt tgtaaatttt gaaatgactt 1260 atgttataac ttgaccttgg caagagatag aacaggcaca tactcttaca tgttttattt 1320 gttgattgac gttacttaag gaacaagctt ttcgtggtat tatttttttt tatgcaacct 1380 gcctatacaa ataacacttc gataagcaaa gatgaatttt ttttataatg ttttacgaat 1440 actaattgtt ttatctctac atcctttaga tataaacaat gattgtacta tattctgaaa 1500 tgctacactg ctcaaatcaa tgtattttga taaattcatc aatttatact ttagacataa 1560 aactagcttg taaagcaatc ctgtacatgt tataaccaac gtaatcttta ttgtgaaaaa 1620 ttgaaaattt cagcaagata cttgtcataa ccaaaaaaaa taaaaaaaaa ccaaattatt 1680 aaacagaaat aatgaagcta taaataaata tgatcaatta tgtattctct tctaagtaac 1740 cttattattg ttttcaaaac tcatcctgct tttcctgttt tatatttgaa ccctgagtta 1800 caggttcgtc catttcctga gcgtatataa tcataggttt tgactctaaa gtttggcctg 1860 gaagttgctc ttctaactca acaaaatcca ttcctcgtaa ctcttcttca aaagatgcac 1920 gaatatgaag gcccggtact agatctacta acagacatat gatagctgtt atgacgaaag 1980 accatgcagc aacagaggta aaacctgcaa attgataacc catttgtttc cagtgatgaa 2040 cggcccagcc cccgtctata actgtagcgc catctgaggc agcgacatcg ggatgcgcta 2100 ctacaccgag cacgatggag ccaacaatgc cgccgatacc gtgtaagtta aagacacgaa 2160 gcgtttcatc aacgccaatc cattcattga ggtcatgaag aaagttacat accaatgccg 2220 gtacgatacc cccagcagcg gctccccatg gaaatacaaa tccacaggct ggtgtgatac 2280 ccactaaccc tgcaatggca ccttcgcaaa tacctatagt ggaaaacttt ctataacgga 2340 tgtaatcaat aatcgcccat gtcaaagcac caaatgacga ggaaatgagc gtgttggtca 2400 tgatataagc tgtacgaata ttaacagtca atagagtacc agaattgaag cagagccatg 2460 caaaccaaat caaaacaacg ccaatgtaaa ccataccagc atcatgcgga ggattatgag 2520 ctatctttcc tctgccgaag gaattcttcc aggaaacaga tttgaaccca aaccaccgct 2580 tccaattagc tttgcagttg ttttgggaag acgacggtaa atctgcatta tcggtcgacc 2640 gaattgaatc gggtctgtct ggctcgtcga caacaatgcg acgacctaaa cataaggaat 2700 aagcgagcgc agcaaaacca gatgaaatat gtacgggacc gccgcctgca aagtcaaggg 2760 cacccaatgt gtagagccag ccattgggtg cccatgtcca gtatgcctgt ggacaataaa 2820 ccagcgtaat gtataaaaaa gatattacga gagagggaat tagcctaccg cgctcagcca 2880 ttgccccggc aaacaattga gctgtcgcta cagcaaagag accaccaaat ggaaagtaaa 2940 caattgctgg aattgtggac cctggtatat atggttctaa ccaaagatgg ttcatccctc 3000 cttgccacaa cgttccataa aaagaggacc ccgatgagca agcaagagag tatccaaaca 3060 gataccattg aataaacacc actgctgtaa ccaaaaacga ctgagtcaat attgagagag 3120 ccgaattctt tctaaccatc ccagcataat aaagagctat accgggggtt acggtaaata 3180 ctaccactgt actcaaaagt acgtacgcta tatcagcatt tgagtattcg ttgggaaaca 3240 gttctgttac agtcgcgata gtggagtttg cgtcgcgacg taatagcgca ttcggctcgt 3300 taagcatctt ttcgtacacg acaaataaat cgtaaatcag tcgtaaatta taccgtacgt 3360 cacagtatcg tacgtaaaca gagagataaa tagaggataa gtaaagaaag tctgtgaatt 3420 tcttaattga tctgtaaact aatatgtaga gaagttctta tctctttacc aaaaaatcac 3480 ctaaagttat caatagtaaa agtaattttc actctttctc aattgaatcc gattcacaga 3540 tttattattt aacgatatag aaccactttc ggtaaaccaa cgttatttgg cgccttaaaa 3600 cgtcttattg tattctaaga atgagatgct gtatatttta gtgtagtatg ctatcttaaa 3660 aaacatgtaa gctacgcagt ttggtatctg atttaaggat acgtagaact gcggtgagtt 3720 ttccttgtga tctattatat tacgatacac aggttgtata agtagcaact gagtataggt 3780 attgtattaa ctgggttata atgttaccta tcactaatat agctcataac tgaactgagg 3840 aacgaggttc agcagtagct ctatttatag tattcagata atattgatct taatagatta 3900 tcattaagat caatctccat atcgtatcat acatggtacg atatataatt agaacatgtg 3960 acatatagtg atactcaacg tagtgtatta tagcgtagtg tagtattgct gacattgccc 4020 tccccaagat tttctatgta aatctgagga taagtcatat gttctcagat atttagatta 4080 ttgtttttaa tataatcatt gacaattgct ttgtccgctt gtagcgctgt agctaatgta 4140 gtccatcctg acataatagt actcggattt agattcgaaa tgtacttgac atttaagtag 4200 agtacttgtt ctctgttttt atgttctagg atatgaagaa ttgttccaat atcagactca 4260 tcaatggtag cgtaattgag ttctgaatta tgtcgatact tttctaggtg agaaacatga 4320 aaagtagatg aaaacatgtg cttgattgaa tctggaagat ccaattcata gttgtttgga 4380 cccgacttct gtaacacata gaacggtcct gcaaaactag gtgctaattt attggattta 4440 tgaagaaaac ctgttttcgt tcttttgacc ataactaggt ctccaggttg aaattcttca 4500 atttcttgta ttttcatatc gaaatacttt ttcatcttta tgttgtttgt attcaagtgt 4560 tctttaactg tttgaaatac ttggatcgtt tcctgagagt tttcgtcagt tttgtcacta 4620 aagctaggta actctaaagg tgataaagct ggtgaatagc gatgtactat ctcaaaaggt 4680 gtcatttgag ttgctgaatg tatcgcattg ttgtaagatt gttgcactag ggatatatga 4740 tctacccatg tatttggatg tgtgctacat acacatctta gtaatttctc cacagtttgg 4800 tttgtacgct cagtttgtcc atcagtttgt ggtctgtatg gtaacgaaaa tttcataacg 4860 aaattatatt tatgtgcgaa atctttccac gtttgggaag taaaaatatg atcattatct 4920 gcaatgattt cttttggatt gccgaaataa gcaataactc gttgatcaaa cattcgagct 4980 gtttgctctg ctgtaatgga tttcgtacaa ggtactaaga ttgccatttt tgaaaatcgg 5040 tcaactacca cgaaaagtgc attataacca gatgattctg gtaaagctgt aataaaatcc 5100 attgataaag attcccaagg tctttctgat gggggaattg gttgtaaagg tccataaggt 5160 ttatgattcc tagatttgtt tatttgacat gtatggcagt tctgtacata ttcttgtatt 5220 tgttttctta ttcctttcca cgtaaatcta cgtaatataa tgtttgtaag aagttcaatg 5280 cctggatgaa tcaatttacc ttcttcatga tactttttaa taattgtcct agtcagctga 5340 gtatcattag gtaataagat ttggtcttta ctgttaatta gtaagccatc tttgagttgg 5400 atattctctt ccactcgttt gtcttcattg tttagtaaat tcaacaattt tgtatcattc 5460 gtatattctg taaccacttg gtttttaaaa tcatcggtta tcgagatttg attaacaaag 5520 ttgatactat tgtcttctga atcttttgga attggttctg tttcgtcaac aattctggat 5580 aaggcatcag ctatgtgatt tgctgatcca ggtctgtagt taatttcaaa gttgaagtct 5640 tgtaaaaata attgccaacg agctaaacgt ttgttttcag gctcggattc gttagtaatg 5700 cgaccaatta agtttcgatg gtctgttaaa attttgaaag gttcgatagt ggattctaaa 5760 tagtgtctcc aatgtttgag agacttaatg attgcaagca tttctttgtc cgatacgcta 5820 taatttaatt gtgctttaga catctttgct gaatagtatc caacaggata gtatttatca 5880 tcatcatgtt tttgagacaa tacggctcct acagcgacat ctgaagcatc agtttccagt 5940 agaatctttt tactgaaatc aaagtgtcgt agcaccggag gagaaactaa acattgttta 6000 atgttttcta tcgcttgggt ttgtgttggt gtccatttcc agcgtacatc ctttttcaaa 6060 agattattga gtggatgtgt taattgtgat gtctttggaa tgaatttcct aagataattg 6120 acagaaccta gaaattgtcg taattcttta cgattcttag gttgcttcca ttgtaagact 6180 ttgtctatat tttcttgaca aggcgtaaat cctttttccg aaatgtgata ccctataaat 6240 tttacttgtg attggtgaaa ttcacatttt gcttgattga taattaagtt cgcatttttc 6300 aatttctgta gaacgtcttt aacatgtttt acatgttcag attccgattt tgaatgaatt 6360 aaaatatcat ccatataaca tactacatgt gattctttgg cttcaccaag tattgtattg 6420 ataaagtatt gaaaatgtgc tggagctgta gatatgccat aaggcattac tagatattca 6480 aaaactccac gaggacagcg aaaagcaagt ttatgttcat ctccttttct tactcgtatc 6540 aagtgatagg cacttttgag gtcaagttta gtaaaaattg tagaaccttg tattttagca 6600 agtaattgtt caataagtgg taacggatat atattgggtt tgacatactt atttaaaggt 6660 ttgtagtcaa ccaccattct caaggtgcct tcctttttcg gaacgaacat tactggacag 6720 gcgttaatgg ctttagattc tcgtataatt ccacttttta atccttgatt aatttcatca 6780 ttcatagctt gcatttttcc cggtggtagc gggtaatttc tgataggtaa tctgtagttt 6840 tcttgagtta gttcaacttc aaattctaac ccttttattg gctttggtag cttttccgta 6900 ttggtttctg cagtaatgtc tttgaattct ttatagatat ctggtaactc aggttccttg 6960 acaatatttg aaactttgtt catttgagag agcgtgtgtt tactgctaga tatttcaatg 7020 ttattgtcat ataatgttgt gaaggagata gcagctggat gcgaaaattt ctttacaacc 7080 aagaattctg ttttgattga tattccattt agacttatgt taagttttat tgttttgcga 7140 ttaatcttat ttggataaac tccaccatat atcacacttt ttgaccaggg tctggtaggc 7200 agtttatgtg ctcgaacagt ttcttctgtt ataatatttg cttgagcgcc cgtatcgatt 7260 agacagggta ttgagcactt gaagtctgga agttcagctt gtaataccat ttcgtaacgt 7320 ttcctagtat gatttaggaa tttgttagat gagtattcta ttctcgaaac atttgtcttc 7380 ctcaggtttc tgctattagt ggtgttattt ttctttgaaa gggactcttt tcctagattt 7440 ttattttgcg gttgaaaacg cttgtgagtt ttaccatacg aggctgttct tttgtcctct 7500 aaaaagtcat aaatttcact gatttctgat ttccagtaat ttctttcctt taatttcctt 7560 aaggaatatg gcagcatcca taatataaac aagcgagtat ggaaatcatc aacatttgct 7620 tttgacatga gtttccttat aaattgaact ttgtccaatt gatttctaaa accttcaaat 7680 gttttagtta aacgatcacc tttgttggat ccttgtactt tccctgtttg tctgagtaat 7740 tcttgccatg taagacttcc attctcagaa aacatgcgtt cagcgaattg ttgctctaat 7800 tcttctaggt gattcaatgt atactgtctt ttagtatgct catttgggaa taatgaaggg 7860 tattcagtaa agtgttgatc aagttttgaa atgtaacttt caacatcctt atttggatcg 7920 aatttcccta tctctggtac atgcttcgat aatatttttg caaaaaggtt tattaaatgt 7980 tcgtctgatg tttgaattcc atccaaattc tctggtctcc atcgttttgc tcttgctttc 8040 atataacgat aatttgcgta ggacattgta tatgtttccc tttgggagat ttcaaaaggg 8100 ataacagtcc ttccaaagtt ccttctcctt tgaacccaga aggagagaaa tatatatatt 8160 tatgatatat atttattcaa taattccttt ttcctaaaag gagttaattg tagatcacaa 8220 gagttcagtt attgtaagct acgcagtttg gtatctgatt taaggatacg tagaactgcg 8280 gtgagttttc cttgtgatct attatattac gatacacagg ttgtataagt agcaactgag 8340 tataggtatt gtattaactg ggttataatg ttacctatca ctaatatagc tcataactga 8400 actgaggaac gaggttcagc agtagctcta tttatagtat tcagataata ttgatcttaa 8460 tagattatca ttaagatcaa tctccatatc gtatcataca tggtacgata tataattaga 8520 acatgtgaca tatagtgata ctcaacgtag tgtattatag cgtagtgtag tattgctgac 8580 aaaacaaaga cagacgcgtt tcaaaataag atgtaaacaa tgttttgcac ttgcactttg 8640 cctaaactat tttcaaggag agattgcttt agaagactct tctgcaagtc ctggtattaa 8700 tttctaatgc gtgtacctcg tattttagta tcttagaatg gtttaatata ctaatttgac 8760 attttttttt atctaagtta ctaggagcct tatactgact gatattttct tatttaattc 8820 atcaaccaac aaatgacttg aatgaatacg tttgcctccg ttttcaatat cgataggtct 8880 catcccttct gtaaggggcg tgcactatag tgaacaatcc tgttaagtag gattatcgaa 8940 cccgacagat aaagtgtata tcggtgatta aaaagcatta tgcccaatga ggctggaaac 9000 cgatttgtga acggcgcaag ctggtatcga gtattttctc ttacattata gatagggaag 9060 tgtattagat gctgaataac atcaggaatt atctaagaga catgcaagat aaacatgaga 9120 aaccggctaa tatgggatat ttacaacgaa tcaatgtatc attgatcctt aagggtttga 9180 ttaatcggct aaacgaagtt atttgactga atagataaag tgtcgagcat gttgacattg 9240 agatcattgt tataaataaa atagatggga acgtcaatta gtgttattgt ttttcaaatt 9300 caagcataag ttgatttctt tgaatctagg ctcgtaaaga tttgtaaagt cacatacatc 9360 cctcgatccg atcgaaatca tacttaacca tataaaccct tattattgaa agcgatttct 9420 gcatatttgg ctatcactct cagtttcaca gccgaaaaaa agtctaagag ataaggcgat 9480 aatttgttaa tattttaagt tgcttttttt ttttttaatt tcttcttttc tctagtttcg 9540 catcgtgttg ctttctgtct tgtttattta taatcttagt tatctaaaat ttatatattt 9600 tcatatatat atatatatat atatatacat acgatatccc ttagctagct gttgaatatg 9660 gcttattatc ctcaccttcc ctatcatcat catcaccata cttccgttcc cggtgaacgc 9720 cttagcgatc ctttggatcc gctgtctgca gacgagctaa aactcgctgt tgaaattatc 9780 cgtcatgagt atccttccaa gcacttcgcg ttcaatgtag ttactctgga ggaacccccg 9840 aaagcgaagt acttgcattg gaaatactcc aaggaagacg ctcacaagcc cgagcgaatt 9900 gcgttggctg tcctactcga aaagggcgtg ccaggtattt tggaagcgcg ggtcaacttg 9960 actaaagcag aggttattca aattgagcat attactggag tttgcccgat ccttacagct 10020 gacatgcttg taaatactga acaaattgta cgtaaggatc ctgctgttat tgagcaatgt 10080 attttgtcgg gggtgcctcc tgatcaaatg gatcatgttt attgcgatcc atggactatt 10140 ggatatgatg agcgctatgg aaatacacga cgcatgcaac aagctatgat gtactaccgt 10200 tctaatgaag acgattctca gtattcgcac cccttggact tttgtcccat catcgatact 10260 gaagatcaga aagtcgttgc tatcgacatc ccacccgttc gtcgtcctct atctaagcac 10320 aagcattcca atttcaataa gaaggatatt gaggccgagt tgggtaagat gcgtgaagtg 10380 aaaccaatct ccgttaccca gcctgagggc gtcaatttcc gcatgaaggg tcgttacatt 10440 gaatggcaaa acttccgtat gcatattgga tttaattatc gcgaaggtat tgtgttatcg 10500 gatatatctt ataatgacaa tggccacatt cgtcctctct tctatcgtat gtcaatcgct 10560 gagatggtgg ttccttatgg taatcctgag caccctcatc agcgaaaaca cgcctttgac 10620 ttaggtgaat acggtgctgg ttacttgact aatccccttg ctcttggatg cgactgtaag 10680 ggtgttattc attatttaga tgctcacttt gtgaacaata ctggtgaggt ggaaaccgtt 10740 aaaaatgcta tttgcattca tgaagaggat gatggtgttt tgtttaagca ttccgacttt 10800 cgtgacaaat tccgtactac tatttctgca cgcggcatta gattggtaat ttcccaaatc 10860 tttactgctg ctaactatga gtatatggta tactggattt tccatatgga tggtgttatc 10920 gaatgcgagc ttaagttaac cggtatattg aacacgtatg ctatgaatga aggggaggat 10980 ctaaaaggtt ggggtaccca agtttatcct caggttaatg cacacaacca tcaacatttg 11040 ttttgtctcc gtcttaatcc aatgttagat ggatacagca attcggttgc tgttgtagac 11100 ggtgtaagtg gtcctggtga gcctggatcc aaagagaatt attatggaaa tgctttcacc 11160 actgagcgta cggtacctaa aactgttaaa gaagccatct gtgattacaa tagtgataca 11220 agcagaacgt gggatatatg taacccaaat aagttgcacc catattcagg caagccagtt 11280 tcatataagc ttgtatctcg agaaactcca cgcttgatgg cccgtccagg atctttggta 11340 tcaaatcgtg caggttttgc tcgtcaccac atccatgtta cgccatacaa agatgggcaa 11400 atttatcctg ccggtgacta tgtccctcaa acatctggcg aaccaactaa aggtttgcct 11460 gaatggattg ctgaagagcc agacgcttcg gttgataaca cggatatcgt tgtttggcac 11520 acttttggaa ttactcactt ccctgctcct gaagatttcc cattgatgcc tgcagaaccc 11580 attcgtcttt tattacgtcc tcgtaatttc ttccttcgca acccagctct tgacgtaccc 11640 ccttcgaaga atgttactac ctctgaggtg aagcaggcac accatcatgg taatttacac 11700 atgatggata tgatgaagag tctaacagat gccacttctg aatttgcatt tggagagaaa 11760 ttttgcgaaa aacataaagg tgatcacttc ttttagagat tcagatattg attgaatgac 11820 ccgaaaccat tttggaacgt agatgtacat ataatgagaa agccatgaat cagcttttta 11880 ttggaataag aagtgatgtt tagtttttgg ttaatcagtg tattaaatac tagctaactg 11940 tcaaatccaa caatacatat atcattattc cttaaatttt cttcttagta tttattattg 12000 acgaagtatt gaatgtgctt aatctttacg aaattgatta tacttaaaac gttttattaa 12060 tatcttctac taaggcaagc ataatctatc cgcattgaac ttagtcaagg ataatgcctt 12120 tcccaaccga atttaaaaat caatgagaat aacaaatatt gaaatttcaa ttgatattga 12180 caatagtaat tacagttgtc ttctttttct aatatccatt ttcctaaagc caaaaaaaaa 12240 ataaaataaa ataaagttaa tttattcata tccatcaaac gcgaaacata atacacatcg 12300 taaaattcaa taaaatagct ccaaacgatt ggtatgttga atcgtttaca gttattctat 12360 ggctgtcaaa ttaatagccg gtaacattcc agccagatga tggcaaagca gaagttgtat 12420 tggtactaga tagtacagtg gaaaaaccgc tgctagagag actagtgaaa ctgcttgtcg 12480 acacactgga agaaatagtg ctagaaatag aagggattga ggtagtggag gatacagcgc 12540 tagggctgga tgaagtcaaa gtagtagacg acacaaggct ggagctggat gtagtcgatg 12600 tggtggaaga agcagcacta gagctagatg aagaaggatc gatatcaact ggaatacatt 12660 gagaataata tggaccattg taaatacatt cggatcctgg ctcacagcaa gttgggccat 12720 tgtaattgat gccgccgcac tgttgatata actttgcaca gggtcctgta taatcaactg 12780 ggatacattg cgaataccag ggatttgaat agatacaaga actacctact acacaacacg 12840 tggggccatc atagtaaata cctccgcaag tcccatatct gggtgaacac tggcttgcgc 12900 ttgttttgga gaccagagac aaagctaatg tcaatactgt caaaaacaaa ctttgagtaa 12960 gcattttaaa cgagaaaaac acaatactaa tagactcgga gagagtaaat ttctaagaaa 13020 agaataagtt caagggttac tttaaagttg cagagagata tgtttctatt tctgaatacc 13080 acgacaaaac agacttatag caacagtcga tcctgacaga gtcgccttgc ccatgacttt 13140 ttatacatca cagaagtaag actttcacaa acgtagcaat actgcaaggc agaaatgtag 13200 acgtgatcac atggtgggcc accagtgtgc gaatgaaaag acactaaaac cttctaacgt 13260 tcccataaaa cgatccaata ttctttcaaa taagatc 13297 //