ID SPAC23E2 standard; DNA; FUN; 14000 BP. XX AC Z68887; XX SV Z68887.1 XX DT 26-JAN-1996 (Rel. 46, Created) DT 08-JAN-2001 (Rel. 66, Last updated, Version 5) XX DE S.pombe chromosome I cosmid c23E2. XX KW gaf2; GATA zinc finger; serine rich protein; transfer-RNA Val; KW tRNA Val anticodon CAC. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-14000 RA Skelton J., Churcher C.M., Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (22-JAN-1996) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; Q10134; Q10134. DR GOA; Q10135; Q10135. DR GOA; Q10136; Q10136. DR SWISS-PROT; Q10134; FEP1_SCHPO. DR SWISS-PROT; Q10135; YAR2_SCHPO. DR SWISS-PROT; Q10136; STE7_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c23E2 overlapped at the 5' by SPAC13C5 (Z50112) and at the CC 3' by SPAC24H6 (Z54142). XX FH Key Location/Qualifiers FH FT source 1..14000 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c23E2" FT /map="IL" FT misc_feature 1..659 FT /note="overlap with cosmid SPAC13C5, EM:Z50112 S.pombe FT chromosome 1" FT CDS 3586..5280 FT /db_xref="GOA:Q10134" FT /db_xref="SWISS-PROT:Q10134" FT /label=gaf2 FT /note="SPAC23E2.01, len:564" FT /gene="gaf2" FT /gene="SPAC23E2.01" FT /product="GATA-type transcription factor family protein FT Gaf2p" FT /protein_id="CAA93113.1" FT /translation="MAAKPAPFGQSCSNCHKTTTSLWRRGPDNSLLCNACGLYQKHRKH FT ARPVKSEDLKDISPLIQQVCKNGTCAGDGFCNGTGGSASCTGCPALNNRIRSLNASKSQ FT SGRKSLSPNPSSVPSSTETKASPTPLESKPQIVSDTTTETSNGTSRRRSSHNQHEDSSP FT PHEPSVTFCQNCATTNTPLWRRDESGNPICNACGLYYKIHGVHRPVTMKKAIIKRRKRL FT VFNGNANESQHNLKRMSSGDSGSSVKQQSTRDGPFSKSFPNGNGHASGNSGEGLAEHGM FT NTGVLPPASTFPSYNSNFTGFLPSSFNPSPLMTLSRLAAGEPDNNGKVYYSYGPTQEQS FT ILPLPENKHEGLPPYQNEYVPNGIRANQVVYPGQLVAVGNDSSKQLSESTTSNTDNNGV FT ATANQSNPLGMKFHLPPILPVGESVCLPPRTSAKPRIAEGIASLLNPEEPPSNSDKQPS FT MSNGPKSEVSPSQSQQAPLIQSSTSPVSLQFPPEVQGSNVDKRNYALNVLSQLRSQHDL FT MIQELHNLNQHIQQIDEWLRSSDNENMASEHIKSSTPAVVASGALQT" FT misc_feature 3610..3726 FT /note="Match to PF00320 GATA, GATA zinc finger Score 59.81" FT misc_feature 4099..4206 FT /note="Match to PF00320 GATA, GATA zinc finger Score 73.55" FT tRNA 6017..6088 FT /note="tRNA Val anticodon CAC, Cove score 73.06" FT LTR 6092..6359 FT /note="Tf1-type LTR" FT CDS join(6508..6530,6696..9258,9312..10547) FT /db_xref="GOA:Q10135" FT /db_xref="SWISS-PROT:Q10135" FT /label=SPAC23E2.02 FT /note="SPAC23E2.02, len:1273, may use internal Met at codon FT 39, SIMILARITY:Schizosaccharomyces pombe, CAB46762, FT hypothetical 112.8 kd protein., (1000 aa), fasta scores: FT opt: 687, E():5.5e-32, (31.4% identity in 1016 aa)" FT /gene="SPAC23E2.02" FT /product="hypothetical protein" FT /protein_id="CAA93114.1" FT /translation="MPLGRSSWICCAKYFVNTKSRFNEILPPRFTLIVSFYSMNTSEND FT PDGHYDFPEMTEHHSDRASSYANANNVNSTQPQLVSSEQALLAILGGGLQSITPNSVNQ FT NAYSRSTYRTDGGLNSQPVSSLNNQWGNYNPAFLPSRYDSSFHPYTISQAANQPFPQHL FT LGNSNAGVAQQSGMRTIGLPPTVGSSFPQQKSSTYENFFDANSPSSQQFPSTYPSRSQN FT PLSSSGDGSTAIHAGPIQHQNSNAFSNYPYPLDASHLSSQQLLSMYRDQVSHGVTPSTF FT RNHESFMPTQLVSATELSKSVDNAVLPIPPTTAPAVVSPPASSFPLMSSAATSGNISSP FT ALFDSELGARPEGSVAIEPSRVLLQWSSQSSSHTIPSAGASIPTSSLKSFFEHAAEAAR FT KCNLDPRALESFEQHMLSDRLHDPVVLFHYFQIRNSICWLWIKNPTHAISRVEAQGVCV FT DRCLFQLASLAYEFLVRYGYINYGCLSFDSSFTNETNTGTTSSSASKQKTIAVVGAGLT FT GLICARQLTGLFSQYSSSFLSKNELPPKVIILEAKERTGGRIYSRALPVSHTSATQINH FT HTSNSNSISSNSTSLNPKDVTDPSHIPSAIDLGFQFLFSPMDDILLNLLNKQLGIEVTE FT MTGSDLVYDETDTKVLDMVEVKKLNILWEKLLEYVSVCFFINVEESVRISWISQFQLFI FT DEMFPDHLSKSLSLNASHEFSFKKTMLILIDEVSSYAKLGNSQKKFLIWCFKVAELDDT FT LYPLNTVDTDFSKDILIPKVARRGLSQLPWALQSYPSPLNIHYEKFVSKVTIENDKCTL FT DCKDNSSYEVDQVVIACSPSHFSSNIEFSPGLPNFVTENIKSIDFKPGKKVILRYAAAF FT WRKNIRSFGIIPKSLSQEMNNDENDGKSCFVLRIWNMLPETGVPILVADINPQMTSSSS FT NETSHLIQELHSLIVDHFQNDSNSSADLLDAWVTNWSRNGVYDGLNSYPNFANDKQQYE FT KRFRQSQLSYNLGRLHIAGDYIFSCVGCRTLQRSFLSGLSVCTGIIDSLAPISLTIPII FT GETSRKELDQFLRNSKVNNFDPNAEAQRHLSYQARYRLKKQERLDEHKEEQEQLVTELL FT GYLPEPPSKPNANPFLLYQKMQWHVCRALADEDKRRLTGDSTAKATINETRAKLGKTWR FT QLDDLGKKPWIDEIAAQREAYAGKILRYQRLTKEYEMRAEQIRNDYAAKCQDEPIPDDE FT ARLFMQAQREEEQRKQTQDDNISKSREASDEEYHDDGSSDSGYNGTRY" FT misc_feature 6531..6536 FT /note="possible splice donor site, gtattc" FT misc_feature 6680..6695 FT /note="possible splice branch and acceptor sequence, ttaacg FT aatcgttaag" FT misc_feature 8097..8102 FT /note="possible splice donor sequence, gtatgg" FT misc_feature 8097..8174 FT /note="possible intron in SPAC23E2.02" FT misc_feature 8153..8174 FT /note="possible splice branch and acceptor sequence, ctaata FT ctggcacaacatccag" FT misc_feature 9259..9264 FT /note="splice donor sequence, gtaggt" FT misc_feature 9298..9311 FT /note="splice branch and acceptor sequence, ttaacattgagcag" FT misc_feature complement(11018..11035) FT /note="ttaactatttcgttgtag, splice branch and acceptor" FT intron complement(11018..11278) FT /note="splice junction removed from prediction, evidence: FT No intron was detected in cDNA: The ste7 gene mutated at FT the splicing donar site predicted in SPAC23E2.03c shows FT no deffect in conjugation process; GFP fluorescence was FT detected in cells transformed with a plasmid comprising the FT ste7-GFP fusion gene(w/o intron)- splice removed" FT CDS complement(11227..12936) FT /db_xref="GOA:Q10136" FT /db_xref="SWISS-PROT:Q10136" FT /label=ste7 FT /note="SPAC23E2.03c, len:576, splicing at C-term may not be FT real, SIMILARITY:Saccharomyces diastaticus, AAC49609, FT glucoamylase., (1367 aa), fasta scores: opt: 297, FT E():1.2e-07, (24.1% identity in 518 aa)" FT /gene="SPAC23E2.03c" FT /product="required for mating and meiosis" FT /gene="ste7" FT /protein_id="CAA93115.3" FT /translation="MFLEIILDSATYSFDRVITGKICFETNAATSPRSFQIQLRIKGYA FT VYHHGFLSSPSHKHPTTASASDSDEATEIFTHSQPLPIPAGPSSKSHAIDFKFKFPSKS FT ASSLPCSKSNDSMVNICYMLKATISKRYAFLGSSQSAKAELIMVPPNLAGKPLSANSSF FT GSSAKTFQLPEFDSVTPSASLYKQPSFNSNPAPITTSSATHTSQFSTSSSSSVNSVHTP FT VMVPNPYFQYNSSMTAPSSSSSSVAPFVPRRQFSVSSASDPPQTPISMSPPIPPTPSQF FT SAFMYQNQQSYLSPQSHYENPLSISSRPSPCCPSTPSSAVTLSNGFDSQSNAYNNSGTG FT PPMLYKFPQRSYTAPNTSFNSQRRMSSITSLPTASFCPVKHGVSPPSLAGNQPSPLSSP FT LTNSNVSPSTICSPDNNVTFVNLAPGEKLTFKIEPNDLMDEEEVVENSNMYSIPGKTVA FT TTVCHSSSSSGDFSALSCHRNLSFSESLPTAEDQVHNNHCAVSPSRRSSSNALYLATLP FT MGYERSNSVSYCSDSSLSSPLPDDNMLQDPHALNMAYAKEFDVLINEVLQSL" FT misc_feature complement(11273..11278) FT /note="gtatgc, splice donor sequence" FT misc_feature 14000 FT /note="single base overlap with cosmid SPAC24H6, EM:Z54142 FT S.pombe chromosome 1 true right end (will be left end when FT this is turned round) is at 18 008 in c24H6" XX SQ Sequence 14000 BP; 4464 A; 2528 C; 2526 G; 4482 T; 0 other; gtgacagttt gacggatcca tgcatcgaga agatgaagac ttattacata aagttatgat 60 gaaattgacg gatttcataa actgtgcaag ttagcttttt taaaaaaaaa aaaaaaaaaa 120 aaaaatatta ttattgcgcg tatatttgaa attgtttttg gtcagcaatg tagtagaatt 180 catcgtgaga aagaaactta aattctatat ttattttcta attaactgaa tttaattaat 240 gaattaattg attaagtgtc aaccaatgcg taggctagaa ataaaaaatt gaaactaaaa 300 aatcgataaa ataaaataat aaaaaatatg cgacagatga atgaaataat actttaaaaa 360 tataaaaaca aatgaaatca ataaaactaa ataaaataaa taataaatta cattcaatga 420 aataaggtaa agttaactcg actcaaaaaa gtaaataagt tcataccatg atattctacg 480 tacaatcaat agacatcagt aaagactata tccatgagac tagttcgtga acaatatggg 540 aatatcaaat tcagatatga aaagaacagt ctttacaagt taagttaata agccatatgt 600 aatgaactct acctaatttc aaaacaacca aagcatacgt tgaaatatta aataagatcc 660 attatcaaaa atccatttat ttaaaaaaac agtacgatgt ttaagaaaac acaaaatttt 720 tgtatattcg gttttttaat gctcttacta atacattttc cattctcacc gcttcataca 780 tggttttttg catactgttt tttatttttt tctatatttt attttcccat ctactctttc 840 tcctctataa gatgatttcc atatttccga ggaatttcaa tagctaagat gcgtgggttt 900 tcctttggta tccagcaacc taaccaggtc gataaacgct cacccccatt ttctcctttc 960 ctcttgcaat ctatccatca cattgctatt tgccgagaaa aattcatttc atatctccgt 1020 cgataaatat aggctttatc gcacgtggtt ttgaaatcat tatcgttctt tatgtaattg 1080 gccaaaatcg atctacacca tcttgtcgag actcgagctc agtgatttac gatttttaca 1140 aatctcagct actttatctg catggagtat aaaaattaaa gtggaaatat attttgataa 1200 agttggtatt gctgaactga atatatgatt atctcttttc caaacatatt ctctcaacat 1260 caaacaaaag cattcagcaa ctacaacagg caattcaatc tccctcacca tcactaaata 1320 gtaaaagttg gtaaaaccat tgcaacccgc tcgcccacca ctgttgatag tttctcttcc 1380 ttgaacatcc gttttaacgc tcttctaaac gctttctctg caatcaattc tcctttttgt 1440 tcgttttggt ttagcactat ttaatatcct aattgctctc gtttgatcct tgattgtcat 1500 ttaccgtgtt ggttcttatc ccctatctat cgtcgattat ttcttacaaa attgaacact 1560 tacaccgttt atagtgttgc tcatataccc ttatatagat ataattatat atttagatat 1620 ctgggaagtt cttttttttt tttttttttt ggtcacacca aaatctagtt tcattaaatt 1680 tggtcatcct ttttctgcaa gttggattaa tctttttatc cgcttcaggc aaccataatc 1740 acatctttct ttttttaacc ctgaggccgc aaaaatttgt cgattttggc catcagcttt 1800 tgtttacgta aaactgagaa accacttaca tttgttaagt ctcttttgtc ttgctccaag 1860 tccatagtta cactcttgcc gggttcttcg ccataacaca aataccggtt gttttactac 1920 ataaatttac cttatcgtag ttttatcatt tatttcgaat ccggttatcc ttttcttcct 1980 agaagaaaat actctactta ttgcacctaa ggctcgttct gctggactgg ttgactgttc 2040 agtccatcgt tttaacgcag tcttccgcgc tctttgtaaa actgcctccc ttttggtctc 2100 gctttttcgg tgcctgattg ttaccccttc gttacttgat aatttcattt ctgctgattg 2160 ggccatatta cctgaaccac caccaccgca attggatttt caatataatt acccgatctc 2220 cttccctatc taagctcaca catatctgca taaacaaaat ttgcccacaa ccattcttct 2280 tctacaagta ttaaaagaca gcttatagat aaagttactt gtattgtttt tgatcgttat 2340 cttttactat ttaatagtac tgttgtcgat aaagtttaag tgctcttcct ttttctcgga 2400 gtctgagcga ctttgccttg aaaattcatt tatttctcgt tttttccttc tcttttctac 2460 gcaaagttag tttttgactt atctttttca caactactat cgccgtatga gttatttgca 2520 aggatcttct tctaataaag attttttgct ctcatcacga tttttttact tttcatctca 2580 gttcttttga tctgttggtg tgataaagac tcttttcatt agttcactct catcttactg 2640 gatttggtga atattctcca tcaaaaagct tcttcacttc tttgaatttg ctttatgata 2700 attgactttt tggtatctat ttctccgctc aattcatagg ttgcatcttg gtttatttaa 2760 ccaccattgg aaactgttcg aattctccaa ggtttcttta ctcttttttt tttttacatt 2820 ttttgctttg ccattccttt tcataggata ggctctttgt tttctgcgag tcggttttct 2880 atttattgta tctttaactt tttaactttg ttgaaaagtt tcctttaaca ctctgttaaa 2940 actttcacgt tcttattttt gttcttatta tcccatccgt agtatctctc gtactacctt 3000 tgaaatttgg tgccttggta ctttaaggct tttatttttt gttggtttta ctgaacagta 3060 ttacctttcc tatttctttc ctttttttgt cctatgcttg ttgtgtttcc gttaaaattc 3120 cggaaaataa atcattcacg aagttctgtc accttttaac atattctctg ttaatagtga 3180 tttttgaatt cacttttgga gatttatgct tttttgcatc tctctctgac tcctttattc 3240 cctttttata tttatcataa ttggaacgtg cgcattcctt tctctccatt ttaatatttt 3300 acacatattt ttgttgtttt ttttttatca aggaagaata atttattatt tataatttct 3360 tgtcaatcca ttacggaaat ctcaaaattt tttgaatcca atccatcggt tctcatctgg 3420 gttcaatcaa ttttgcaatt tgtacatatc gatacaatcg ttttcttgtt tttttttatt 3480 ttccattgtg aataagcttg gatcatttcg ttcagtacaa ctcacttaaa gctagcattt 3540 actttgattc gttcgtaatt aactttttta catatcacca aaaaaatggc tgcgaaacct 3600 gctccttttg gccaaagttg ttccaactgc cacaaaacta ctacttcttt atggcgtcgt 3660 ggccccgata attccctttt gtgcaatgct tgtggcttat atcaaaaaca tcgcaagcat 3720 gcccgtcctg tcaaatctga agatttaaaa gacatttctc cactgataca gcaagtttgt 3780 aaaaacggaa cctgtgctgg agatggattc tgtaacggta cgggtggcag tgcttcatgt 3840 actggttgtc ctgctttaaa taatcgtata agaagtctca atgcttctaa gtctcagagc 3900 ggacgcaaaa gtctatctcc caatcctagc agtgtaccct ctagcactga aaccaaagct 3960 tcgcctacac ctctagaatc gaaacctcaa atcgtttcag ataccacgac tgaaactagc 4020 aatggcacta gtagacgacg ttctagtcat aaccagcatg aagactcatc tcctcctcat 4080 gaaccaagtg ttactttttg ccaaaactgt gctaccacaa atactccttt gtggcgccgc 4140 gacgagtcgg gtaatccgat ctgtaatgct tgtggtttgt attacaaaat tcatggggta 4200 catcgtcccg ttaccatgaa gaaggcaatc attaaacgtc gaaaaaggct ggtttttaac 4260 ggtaatgcga atgagtcgca acacaactta aaaagaatgt caagtgggga ttccggatct 4320 tccgttaagc aacagtctac aagggatggt cctttttcta aatcttttcc caatggtaat 4380 ggccatgctt ctggaaattc tggtgaaggt ctggctgagc atggaatgaa tactggagta 4440 ttacctccgg ctagtacatt tccttcatac aacagcaatt ttaccgggtt cttgccttct 4500 tcgttcaatc cttcaccatt gatgacattg tcacggttag cggctggtga acctgataat 4560 aatgggaaag tttattactc atatggtcct actcaggaac aatcaatatt gcctcttcct 4620 gagaacaagc atgaaggatt gcctccttac caaaatgagt atgttcccaa tggtatacga 4680 gctaatcaag tagtataccc tggtcagctt gtagcagttg gcaatgattc tagtaagcaa 4740 ttatcggaat ctacaacatc gaacacggat aataatggcg ttgcaactgc caaccaatcc 4800 aaccccttag gcatgaagtt tcatttacct cctatccttc ctgttggcga gtcagtctgt 4860 ttgcctcctc gaacttctgc aaagccaagg attgctgaag gaattgcttc cttacttaac 4920 cccgaagagc caccctcaaa ttccgacaag cagccatcaa tgtcaaatgg accgaaatca 4980 gaagtttcac cttcgcaatc tcagcaagct cctttaatcc aatcctctac ctcgccggtt 5040 tctttgcagt ttcctcctga agttcaggga tcaaatgtag ataaacgcaa ttatgctttg 5100 aatgttcttt cgcaattgcg ttctcagcat gatttaatga ttcaggagtt gcacaattta 5160 aatcagcaca ttcaacaaat agatgaatgg ctgaggtcct ctgacaatga aaatatggct 5220 tctgaacata ttaaatcctc aacccctgct gttgttgcat ctggagctct tcaaacataa 5280 acttgattgg catgtttgtc gtgcggcata tttatttatg gtaaacaaat tagatattat 5340 cccgtttagc tgtctattac ttacaagcat gacattgtat actatgagtt tagggtaaaa 5400 tacttcacat gattcttatt ggtcttttgt tttgcgttag ttttggtatt ggccaagtcc 5460 gtctgcggtg ttatattcgt taagagctgg aaaataatat tcagtcctta gcgatttacc 5520 gttaaattta gagttaacat atatgttttt aatgaaatcc tatgtggagc attttttatg 5580 atattaatac gcatcgaaaa agcagatatt gagaaaaaat aatactaccg gatttatatg 5640 gtatgtagat agttaatata ttaaatatat ttaaactgcc cgagtgcaaa ctcatttgga 5700 aattgtcaat tcattaatat atttttacaa tttttcgggg gaaaaaacat ttgtatacaa 5760 ctatttaaaa cggaaaatgg agttgcttgt aaaaagcagt atccatggtt aattagttca 5820 ttcgcaaaaa gtcattgctt gacttttaaa actatatgat taggctgaaa ttttaattgt 5880 tcattacagc acatatataa aaaacttaca cttaattttc agctcaaata acttcgctat 5940 tcattattta atctatttaa atcaataata atgtaattat gatatatatc atttagtttt 6000 tctgttaaca accaacagtc ccgtgttcta gtggtatgat ttctccttca cacggagaag 6060 gtcccgggtt cgatccccgg cgggactaga ctttttgtaa aattcaacaa tagcgaactt 6120 gaaccataat gagatgtttt agtataatat tgataaacag ttaatctaca ctactactct 6180 aaacatccta agcttttctg aatcttaaca gcaatgtaac atatttttgg attgttataa 6240 taatttactc catttgttct attctccgct gactatactt tcaagtgtat tgtaatattg 6300 ttttctgcaa gttgaaatca acgagtttag gtagtagtct ttagcatgaa agagctaaca 6360 cattaatgca ataatttgga aaatgaatac aaattaatga acttcacatt tttcgttcat 6420 catttccaaa gtgttaagcc tgtagaagag agcaaatgcg atcgtagaat aatactcgca 6480 atatgaatca gataaatagg caattgaatg cctctcgggc gttcttcatg gtattcaaat 6540 aattaaagac acatgtatta tctaaaagaa aaatataaat tctggatagt ctgatagatg 6600 attgattgga cttgacataa aaatgcttat aatatttgtc gttatcccat tatgctataa 6660 tatttagaac gatatttttt taacgaatcg ttaaggatat gttgcgcaaa gtactttgta 6720 aacaccaaat cgagattcaa tgagatttta ccacctcggt tcactttgat tgtatctttt 6780 tactctatga acacgagcga gaatgatcca gatggtcatt atgactttcc agaaatgaca 6840 gagcatcatt ctgaccgggc ttcatcatat gctaacgcca acaacgttaa ttcaactcaa 6900 cctcaattgg tgagtagtga acaagcgctt ttagctattt taggaggtgg attacagtct 6960 atcacaccta attctgttaa tcagaacgcg tattcaaggt caacttatcg tacagatggc 7020 ggcttaaatt cacagccagt tagctcactg aacaatcaat ggggaaacta taatccagca 7080 tttttacctt ctagatatga ttcctctttt cacccttaca caatttcgca agcggctaat 7140 caaccatttc ctcagcatct tttaggcaat tcaaatgcag gtgtcgctca gcagtctgga 7200 atgagaacaa ttggattacc tccaactgta ggttcctctt ttcctcaaca aaagtcatcc 7260 acatacgaaa acttttttga tgcaaactct ccgtcttctc agcaatttcc atctacatat 7320 ccttcacgat cacaaaaccc gctttcttcc agtggagatg gttcaacggc aattcatgca 7380 ggccccattc aacaccaaaa ctcaaatgcc ttttccaatt atccgtatcc attagacgct 7440 tctcatttat cttctcagca acttttgtcg atgtatcggg atcaagtttc tcatggagtt 7500 accccatcta cattccgcaa tcatgaaagt tttatgccta cacagttggt atcagcaaca 7560 gaattatcta aaagtgttga taacgcagtt ttgccaatac cacctactac tgcaccggca 7620 gttgtatcgc ctcctgcttc atctttccct ttaatgtctt cagctgctac atctggtaat 7680 attagtagtc ctgcactttt tgattcagag ttaggtgcta ggcctgaagg ttctgttgca 7740 attgagccgt ctagagtact gctacaatgg tctagtcaat catcatctca tactatacca 7800 tctgcaggag ccagtatccc tacatcttct ttaaagtcgt tttttgagca tgccgctgaa 7860 gcagctcgta aatgcaatct cgatccgagg gccttagaaa gttttgaaca acacatgctt 7920 tctgatcgtt tacacgatcc cgttgtatta tttcattatt tccaaattcg taacagcatt 7980 tgttggcttt ggattaaaaa tcctacgcat gccatatcca gagttgaagc tcagggcgta 8040 tgtgtcgatc gatgtttgtt ccaattagcc tctttagctt atgaattcct tgtaaggtat 8100 ggatatataa actatggatg cttgtccttt gattcatcct ttacgaatga aactaatact 8160 ggcacaacat ccagttctgc atcgaagcag aagactattg ctgtagtagg cgctggtctt 8220 actggtttga tatgtgctag acaacttact ggcttatttt ctcagtattc ttcatctttt 8280 ttgtcaaaga atgagcttcc tcctaaagtt attatacttg aagctaaaga aaggacagga 8340 ggtcgtattt actctcgagc attgcctgtt tctcatactt cggctaccca aattaaccat 8400 catacatcta attcgaattc tatttctagt aattccactt ctttaaaccc caaggatgtt 8460 actgacccgt cccatattcc ttcagcaatt gatttgggat ttcaattttt attttcgcct 8520 atggacgata ttttgcttaa ccttttaaat aaacaattgg gtattgaagt tacagagatg 8580 actggctcag atttagttta cgatgagacc gatactaaag tattagacat ggttgaggtg 8640 aaaaaattaa acattttatg ggaaaaactt ttggaatatg tttctgtttg cttttttatt 8700 aacgttgagg aatctgttcg tatttcttgg atatcccaat ttcagttgtt tatagatgaa 8760 atgttccctg atcatttgtc caaatcactc tcattaaatg cgtcacatga attttccttc 8820 aaaaaaacaa tgctaatact aattgatgaa gtttcttctt atgccaaact cgggaacagt 8880 caaaagaaat ttctgatatg gtgttttaag gtcgcggaat tggacgatac tttgtaccct 8940 cttaacacag ttgatacaga cttctccaaa gatattttga ttccaaaagt tgctagaaga 9000 ggtctatctc aactgccatg ggcattacaa tcttatccat ctcccttaaa tattcattat 9060 gagaagtttg tatctaaggt aactattgaa aatgataaat gtacccttga ttgtaaggac 9120 aactcttctt atgaggttga ccaagttgta attgcttgct ctccttctca tttttcttca 9180 aatatagagt tttcaccagg tcttcctaat ttcgtgactg aaaacataaa aagtatagat 9240 ttcaaacccg gaaaaaaggt aggtttttat ttatttattt ttttttcaat tataaagtta 9300 acattgagca ggttattctt cgttatgcag ctgctttttg gcgaaagaac attagatcat 9360 ttggtattat accaaaatca ttaagtcaag aaatgaacaa tgatgagaat gatggtaaat 9420 cttgttttgt tttgagaata tggaatatgc ttcctgaaac tggtgtccca atattagtag 9480 cggatatcaa tccacaaatg acaagttctt cttctaacga gacctcccac ttaattcaag 9540 aattacacag tctaatagta gatcattttc aaaatgattc aaacagctca gctgatttat 9600 tagatgcttg ggtcacaaac tggtcgagaa atggtgtcta tgacggctta aattcttatc 9660 caaattttgc caatgataag cagcaatatg aaaaaagatt taggcaaagt cagttatcgt 9720 ataatttggg tcgcttgcat attgctggag actatatatt cagttgcgta ggctgtagga 9780 cattacaaag atccttttta tctggccttt ccgtatgtac agggattatt gattcattgg 9840 ctccaatttc cttaaccata cctatcattg gagaaacctc tcgcaaagaa ttggatcagt 9900 ttttgcgaaa ctctaaagtt aataattttg atcccaatgc tgaagcacag cgtcaccttt 9960 cttatcaggc aagatatagg ttgaaaaagc aggaaagact tgacgagcat aaggaagaac 10020 aggaacagct tgtaactgaa cttcttggtt atttacctga acctccttcc aagccgaatg 10080 caaatccctt tttactttac caaaaaatgc agtggcatgt atgccgtgca cttgctgatg 10140 aagacaagcg aaggttaaca ggagatagta cagcgaaggc tactattaat gaaacacgtg 10200 ccaaactagg gaaaacttgg cgccagcttg atgatttagg taaaaaacct tggattgatg 10260 aaattgcagc acaaagagaa gcttatgctg gaaaaattct tcgttatcag cgcctaacta 10320 aagaatatga aatgagagcc gagcaaatac gaaatgatta tgcggccaaa tgccaagatg 10380 aacctattcc cgatgatgaa gcaagattgt ttatgcaagc tcaacgagaa gaagagcaaa 10440 gaaaacaaac tcaggatgac aacatttcca aaagtcgaga ggctagcgac gaagagtatc 10500 atgacgatgg atcttctgat tcgggttata atggaacacg atattaaaag aaaaaaaatc 10560 aaatcacata ttgtttttta aaagtttagt tacttcgcat cattacaaat acccttaaaa 10620 ttttatgtac atatatattc tcgtcatgcc ctaaatgaag cattttatca aattgctaat 10680 ttcagcaaat tgtttaagga aaatctaaaa tacatgtaca cttctcgtta gccagtagcc 10740 aacctgattt aatgccgaag atgtaagaga taaaagatga tatcgtaaac acagctacta 10800 ctctcactct ttaggatgta atgcatgtta ccattttgcc attaacataa tattcaagca 10860 acaaatgata ttactagtac gcttgtgaaa taaataaaaa aataagttat tagaaaaaaa 10920 gtaattaaaa ttaactaaga atcattaaat taagccaaaa cagatgcggt tgtatttgtt 10980 gcagacacca tggacactat gtatctcaaa gcaagtacta caacgaaata gttaaaaaaa 11040 aaacataaga tgcatatgat attaaaataa aataatataa aaatgccgag ttattgactc 11100 cagtccatat ttggacatgt ataattaaaa gcattatcca aaagttaata ggagatggca 11160 tctcaattgt caaaaaaaaa gtggttgtta taaagactcg taattcagga agtctgttat 11220 aaataattaa agagactgta agacttcatt gataagaaca tcgaattctt tagcatacgc 11280 catgttcaaa gcgtgtggat cttgtagcat attgtcgtca ggcaaagggg agctaagact 11340 tgaatctgaa cagtatgata cggaattaga tcgttcataa cccattggca aagtagctag 11400 atacagagca ttggatgaac ttcttctgga aggcgatacg gcacagtgat tattatgaac 11460 ttgatcttca gcagtaggca agctttcaga aaatgataga tttctatgac atgaaagagc 11520 tgaaaagtca ccggaagaag atgacgaatg acaaactgtt gtagcaacag tcttaccagg 11580 aatactgtac atattggaat tctcaaccac ctcttcttca tccataaggt cgtttggttc 11640 aatcttaaag gtcaacttct caccaggtgc taaattgaca aaggtgacgt tgttgtctgg 11700 tgaacaaatg gtagaaggag aaacattaga attggtgagt ggagaagata aaggactagg 11760 ttgatttcct gccaaagatg gaggtgaaac gccgtgttta acaggacaaa acgaggcagt 11820 cggaagtgag gtaatgcttg acattcgacg ttgagaattg aaagaggtat tcggggcagt 11880 gtaagaacgc tgagggaatt tataaagcat cggaggaccg gtacccgaat tattataagc 11940 attggattgc gagtcaaaac cgttggatag ggttacagcg ctactaggcg tactagggca 12000 gcaaggcgat ggacgtgacg atatggaaag aggattctca taatgtgact gaggactgag 12060 gtatgactgc tgattttgat acataaaagc agaaaactga gaaggagtag gtggaatggg 12120 gggtgacatg gaaatgggag tttgaggtgg atctgaggct gaagaaacag aaaattgacg 12180 gcggggaacg aaaggagcta ctgaggaaga ggatgaagat ggagctgtca tggatgaatt 12240 atactggaag tagggattag gaaccataac gggggtatga acggaattca cggaagaaga 12300 agaagatgta gaaaattgag aagtatgagt agcagaagag gtggtaatgg gagcggggtt 12360 ggaattgaag gaaggttgtt tatagagaga tgcagaagga gtaacggaat caaattccgg 12420 aagttggaat gtcttagcag aagaaccgaa cgatgaatta gcactcaaag gtttaccggc 12480 caaatttgga ggaaccatga tgagttcagc ctttgcactt tgagaagagc caagaaaggc 12540 ataacgctta ctgatagtgg ctttgagcat gtagcaaatg ttgaccatgg aatcattgga 12600 cttggaacaa ggaagagacg aggcggattt agaaggaaat ttaaatttga agtcaatggc 12660 atgagacttt gaagagggac ctgctggtat aggaagaggc tgagaatgag taaaaatttc 12720 tgtagcttca tcggaatcgg aggcagaagc agttgttgga tgtttatggg aaggagaaga 12780 caagaaacca tgatgataaa cagcataacc cttgatgcga agttgaattt gaaaggaacg 12840 aggagaggta gcggcatttg tttcaaagca aatttttccg gtgattacac ggtcaaagct 12900 atacgtcgca gaatctagga ttatttccaa aaacatgatg ggtacggaag tacagaaatt 12960 ggtaagtaag ggactggtaa aaatgagaag agagaaacgg aattgctctg ataagaagag 13020 gagaggggaa aggataaaga aaatgagaga tgttgagaag gaatagtcaa atcaacgtga 13080 acgtgaaaga agaaagagag attttaaaga aataaaaaac acactaaaca ctaaatcttg 13140 gaataaaaaa tttaataaca agaactcgat tttctttttg taaacaagaa gaacgacaac 13200 aaaaaggtaa agtatataat gtctaaaagc tggaaattga agaaacagct aaaacaaaaa 13260 tcagaaaacg aaacgcacaa acagatagag atagttagac tgcggagtag atagacatgt 13320 aatcttctga attgagctag atgaggagag aagagatagc aaaagaaaaa gaagaagaag 13380 agagagaaaa aaaaaaaaaa aaaaaaaaac aaattacaaa ataagccttt atatcttaac 13440 ttatcgaagc ttttgcttta ttccaagtat attcagagat agatatacta agaaagaaag 13500 aaagaaagaa ggaaggaaaa aattaaaaat actgctgctg tgcctgacac aacttaaatg 13560 taaatactaa tgatttatgc gactccaatt ttggggctaa cacgatttat ataaagtaag 13620 tgatgcgaga ggggtatacc tgggctttgc tccattttca aacaaagaaa atcaacaata 13680 caaccagcga ttggattgag tcatgctaat cccagcatgg ctagcactca aacaagcaag 13740 caaacaagca acaaagggta acgatgactc cttgataaac cctgtaaatc aatgtgacaa 13800 cgatcctcct agggtgtatg gagtaacggt aaatgggaaa gatttgaagt agaggaggta 13860 ccagggataa agagtacaaa gcatcgagta aagtgatagc ttatcatgtg ctacacgaat 13920 ggaagcgatg cacacttcaa cggtcaaagt aacaagagcg gagtttggag attacgaaca 13980 aagaaagcga gttttgcgag 14000 //