ID SPAC23C11 standard; DNA; FUN; 38391 BP. XX AC Z98559; XX SV Z98559.1 XX DT 14-AUG-1997 (Rel. 52, Created) DT 19-JUN-2002 (Rel. 72, Last updated, Version 6) XX DE S.pombe chromosome I cosmid c23C11. XX KW 40s ribosomal protein; alanyl-trna synthetase; casein kinase ii; cka1; KW component of the U3 small nucleolar ribonucleoprotein; dna mismatch repair; KW Homol D box; Homol E box; inorganic pyrophosphatase; KW mitochondrial dna repair; muts family; paired amphipathic helix; KW phosphatase; php3; plo1; polo box; ppa1; ribosomal protein s12; KW ribosomal protein s23; rps23; serine/threonine-protein kinase; KW transcriptional activator; zinc binding; zinc cadmium resistance protein; KW zinc metallopeptidases; zinc/cadmium resistance. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-38391 RA Brown D., Churcher C.M., Barrell B.G., Rajandream M.A., Wood V.; RT ; RL Submitted (13-AUG-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; O13909; O13909. DR GOA; O13911; O13911. DR GOA; O13912; O13912. DR GOA; O13914; O13914. DR GOA; O13918; O13918. DR GOA; O13919; O13919. DR GOA; O13921; O13921. DR GOA; P19117; P19117. DR GOA; P36611; P36611. DR GOA; P40231; P40231. DR GOA; P50528; P50528. DR GOA; P79057; P79057. DR SPTREMBL; O13918; O13918. DR SPTREMBL; O13920; O13920. DR SWISS-PROT; O13909; YDW1_SCHPO. DR SWISS-PROT; O13910; YDW3_SCHPO. DR SWISS-PROT; O13911; PNK1_SCHPO. DR SWISS-PROT; O13912; YDW6_SCHPO. DR SWISS-PROT; O13913; YDW7_SCHPO. DR SWISS-PROT; O13914; SYAC_SCHPO. DR SWISS-PROT; O13915; YDWA_SCHPO. DR SWISS-PROT; O13916; YDWC_SCHPO. DR SWISS-PROT; O13917; YDWD_SCHPO. DR SWISS-PROT; O13919; PST2_SCHPO. DR SWISS-PROT; O13921; MSH1_SCHPO. DR SWISS-PROT; P19117; IPYR_SCHPO. DR SWISS-PROT; P36611; PHP3_SCHPO. DR SWISS-PROT; P40231; KC21_SCHPO. DR SWISS-PROT; P50528; PLO1_SCHPO. DR SWISS-PROT; P79057; RS23_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c23C11 overlapped at the 3' end by cosmid c13F5. XX FH Key Location/Qualifiers FH FT source 1..38391 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c23C11" FT /map="IL" FT CDS join(217..480,560..874,928..1113,1154..1266,1352..1799) FT /db_xref="GOA:O13909" FT /db_xref="SWISS-PROT:O13909" FT /note="SPAC23C11.01, len:441, SIMILARITY:Saccharomyces FT cerevisiae, YIJ0_YEAST, hypothetical 56.3 kD protein, (491 FT aa), fasta scores: opt: 175, E():0.00024, (26.5% identity FT in 480 aa)" FT /gene="SPAC23C11.01" FT /product="hypothetical protein; similar to S. cerevisiae FT YIL090W; 10 predicted transmembrane helices" FT /protein_id="CAB11154.1" FT /translation="MDQEIRSNNYDISVSTVEDTSFEAMDDSILEIIDDEAPEIQGKPK FT ANISTHFRNMLAMFGNFLSLGFFLVIIVLVGIAFEIGGRFCGLILTLALEVYFFSTALL FT KLFGLRKIALTLHFFEPLLVFILLIIALNASPSIEQNKYASFLASAWNTALLHFTPLFN FT LLEGMASLLVVQALGHLSRWLVHNKSENWMFFILLNASSAISMSLYLLYRVSSFSISNP FT NALMIGFSLATVIVISIYGVASGRANLSEASLMFLYIAYTVYMVCTDFGNPNTSSLEKP FT KFDYLPPNILQSVHYLISTISATLPRTLYNIVLFMVAAAKTVAPSVFATFAFRISVMYA FT VTRILPAIQNNIIFLEYSRTSKQGMWSILSPCILIAVYTNLLLQHLYPTPSFTSPVNQI FT LCSAEIWRWVSAILTLLLYAIELAYSKESDTGQALASHFKLD" FT misc_feature 481..486 FT /note="gtaagt, splice donor sequence" FT misc_feature 540..559 FT /note="ctaacataaatttaaaatag, splice branch and acceptor" FT misc_feature 875..880 FT /note="gtacgt, splice donor sequence" FT misc_feature 913..927 FT /note="ttaacttaaacgcag, splice branch and acceptor" FT misc_feature 1114..1119 FT /note="gtaatt, splice donor sequence" FT misc_feature 1141..1153 FT /note="ttaacatatttag, splice branch and acceptor" FT misc_feature 1267..1272 FT /note="gtaagt, splice donor sequence" FT misc_feature 1335..1351 FT /note="ttaacattttttaacag, splice branch and acceptor" FT misc_feature complement(2103) FT /note="poly A attachment site" FT CDS complement(2135..2566) FT /db_xref="GOA:P79057" FT /db_xref="SWISS-PROT:P79057" FT /note="SPAC23C11.02c, len:143" FT /gene="rps23" FT /gene="SPAC23C11.02c" FT /product="40S ribosomal protein S23; similar to S. FT cerevisiae RPS23A and RPS23B" FT /protein_id="CAB11155.1" FT /translation="MGKPAGLNAARKLRNHRREERWADAHYKKRLLGTAYKSSPFGGSS FT HAKGIVVEKIGVEAKQPNSAIRKCVRVQLIKNGKKVTAFVPHDGCLNFVDENDEVLLSG FT FGRKGKAKGDIPGVRFKVVKVAGVGLSALFHEKKEKPRA" FT misc_feature complement(2141..2548) FT /note="Match to PF00164 Ribosomal_S12, Ribosomal protein FT S12 Score 262.42" FT promoter complement(2633..2640) FT /note="Homol D box" FT promoter complement(2642..2651) FT /note="Homol E box" FT 5'UTR 2729..2922 FT /note="mRNA from spc01712" FT CDS 2923..4719 FT /db_xref="SWISS-PROT:O13910" FT /note="SPAC23C11.03, len:598, SIMILARITY:Saccharomyces FT cerevisiae, YJX2_YEAST, hypothetical 67.0 kD protein in FT pre3-sag1 intergenic region., (593 aa), fasta scores: opt: FT 855, E():0, (33.0% identity in 610 aa)" FT /gene="SPAC23C11.03" FT /product="putative U3 snoRNP component; required for FT pre-18S rRNA processing; similar to S. cerevisiae MPP10" FT /protein_id="CAB11156.1" FT /translation="MTELINSEPTLFLFPNKEDSKQLVEKAIEVFSNIKIPSTSPIQTI FT VTKGLDNWQIYNQLALAAKYALDDLPQVDVENEDEEEDSITSFQDEDDETSHQELSDNS FT EMNNRDDADDEFLGFSGPENLEDVDESSAEDVSGDEAEIMNEEGQQIEQKKDAFGLNDG FT FFDIDNFNKQTLALEEEAVEEGVLGDEDDGIDLLMDPDENMEDSEDESNGPQADSIMYE FT DFFGPKTAAGRRELKKKKAESKRKRTSKPDFKNDVQQNVIEENNESSDNEYATFDRVKK FT DLFASDEEDDVSADQLSSYERDKARLTQQIRELEAENVAKKSWTMMGEATSKGRPSNSL FT LDVDLEFETGAKPVPVQTEETTETLEDLIKNRIISKTFDDVPKRAPVAVTEFRPSELFE FT LNENKSQRSLAEEYEEEFLKKSNADTYKSEADKKKEKEHEEIKALFSEVSRTLDSLASW FT HYVPPPPESTVEIVSNAPTLAMEDVQPTAASDTMALAPQEVYKPSNENREGETITRSGI FT AISSTEMDHQQKQARRRRVRRKHAEKRKQMAEKRRNSGTEQVVRQLSKSNVEVIGKGGE FT RKKVASNSNKYHPIVSSNQLKL" FT CDS join(complement(5676..6216),complement(5045..5622), FT complement(4842..4988)) FT /db_xref="GOA:O13911" FT /db_xref="SWISS-PROT:O13911" FT /note="SPAC23C11.04c, len:421, SIMILARITY:Homo sapiens, FT AAD51135, polynucleotide kinase-3'-phosphatase., (521 aa), FT fasta scores: opt: 493, E():3.4e-24, (34.3% identity in 376 FT aa)" FT /gene="SPAC23C11.04c" FT /gene="pnk1" FT /product="DNA kinase/phosphatase (PMID 11729194); DNA FT 3'-phosphatase (PMID 12056900); required for Normal FT Response to DNA Damage by gamma radiation or camptothecin FT (PMID 11729194); localization of GFP fusion nuclear (PMID FT 11729194); similar to S. cerevisiae TPP1; putative DNA FT repair protein" FT /protein_id="CAB11157.1" FT /translation="MSSKKRKSPPQESLTSYFEKSSKSSKKYGSQNKDSDSSSTCLQQK FT IEIQWSITDSLYIAKYGKLKKTKKFIAFDLDGTLIKTKSGRVFSKDAADWTWWHPSVVP FT KLKALYQDNYSLVIFSNQNGIPRKPSAGHTFQMKIRAIFESLDLPIVLYAAILKDKFRK FT PLTGMWNSFLKDVNRSIDLSFIKYVGDAAGRPGDHNSTDLKFAENIGIKFETPEQFFLG FT HSFVPPNFESFHPKNYLVRNSSSHPYHFKKSEHQEIVVLVGFPSSGKSTLAESQIVTQG FT YERVNQDILKTKSKCIKAAIEALKKEKSVVIGMYSIISTTYAISDNTNPTIESRKMWID FT IAQEFEIPIRCIHLQSSEELARHNNVFRYIHHNQKQLPEIAFNSFKSRFQMPTVEEGFT FT NVEEVPFKCLKDYEDTWNYWYE" FT misc_feature complement(4989..5002) FT /note="ctaaccaattctag, splice branch and acceptor" FT misc_feature complement(5039..5044) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(5354..5377) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT misc_feature complement(5623..5643) FT /note="ttaacatttttcaccctttag, splice branch and acceptor" FT misc_feature complement(5670..5675) FT /note="gtgagt, splice donor sequence" FT 5'UTR 7157..7306 FT /note="mRNA from SPPPAG X54301" FT misc_feature 7198..7203 FT /note="putative TATA box" FT CDS 7307..8176 FT /db_xref="GOA:P19117" FT /db_xref="SWISS-PROT:P19117" FT /note="SPAC23C11.05, len:289" FT /gene="ppa1" FT /gene="SPAC23C11.05" FT /gene="ppa" FT /EC_number="3.6.1.1" FT /product="inorganic pyrophosphatase; similar to S. FT cerevisiae IPP1" FT /protein_id="CAB11158.1" FT /translation="MSEYTTREVGALNTLDYQVYVEKNGTPISSWHDIPLYANAEKTIL FT NMVVEIPRWTQAKLEITKEATLNPIKQDTKKGKLRFVRNCFPHHGYIWNYGAFPQTYED FT PNVVHPETKAKGDSDPLDVCEIGEARGYTGQVKQVKVLGVMALLDEGETDWKVIVIDVN FT DPLAPKLNDIEDVERHMPGLIRATNEWFRIYKIPDGKPENSFAFSGECKNRKYAEEVVR FT ECNEAWERLITGKTDAKSDFSLVNVSVTGSVANDPSVSSTIPPAQELAPAPVDPSVHKW FT FYISGSPL" FT misc_feature 7442..7996 FT /note="Pfam match to entry PF00719 Pyrophosphatase, Inorgan FT ic pyrophosphatase" FT misc_feature 7655..7675 FT /note="PS00387 Inorganic pyrophosphatase signature" FT 3'UTR 8177..8476 FT /note="mRNA from SPPPAG X54301" FT CDS complement(8462..10069) FT /db_xref="GOA:O13912" FT /db_xref="SWISS-PROT:O13912" FT /note="SPAC23C11.06c, len:535" FT /gene="SPAC23C11.06c" FT /product="hypothetical protein; similar to S. cerevisiae FT YNL115C; 5 predicted transmembrane helices" FT /protein_id="CAB11159.1" FT /translation="MNTSQDVNAEAANERSALLPRFLGSHRGNVPENTDTYALTPLFYW FT IRSTSVGLLLITIICHLFLLLNIFISIPIISHLSPGFMPVGFTALAAILLAMQIMFVYS FT PNAPERVTQRIICFLLAIDVLVVFLSPILRHREGWRSNAFVLWAFLMSLWIVITDLMLF FT RQYKEEHPDYDAIAHRGYYWSWSPSTWPWRQVGSLTASTILSVILTILTIHTLVTLIMR FT AYDGALSAPGQLYTVTDSKARVHLECFGSSSSNNKTTVLVEGGEVSVHPFKEWLLNLQH FT TSPDLYEESKDFEGYENDVKPYLSPDTRVCVWDRPGMGWSDNIGSPSSVGIVMDLLTEA FT LAQADVSGPYVLVAHGIGGVYSNVFAARHLSEVKGIVFVDAGSVQTLKDSGQFLSRFLL FT FVRGWLSPLGINRIFGSIFMGKTRQDRVYGMYSWTSDRWVKSKIEESLTGPSFSRYELQ FT SAQSVLPKDLPVSVISAGKSMKRFKKWPDEQRQLSKLTQRTVWDIVNNAPHDVWLSDDG FT GDLIMKRLGEIIYGGWPN" FT misc_feature complement(8804..8827) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop)" FT 5'UTR complement(10070..10376) FT /note="mRNA from spc01094" FT CDS 11672..12004 FT /db_xref="SWISS-PROT:O13913" FT /note="SPAC23C11.07, len:110)" FT /gene="SPAC23C11.07" FT /product="hypothetical protein; sequence orphan; has FT transcript profile on microarray" FT /protein_id="CAB11160.1" FT /translation="MASHFLFTGKPWLQEKTPRLHLHPTWDLKASKSLARFPYTPLESL FT LAPISAFHPTYLNSAAPSKAQSHPVLLAAGVGGIVVRCPSRKPIYRTTRIQYLLLISHF FT TTALFK" FT 5'UTR 12050..12458 FT /note="mRNA from SPRNAPHP3" FT CDS join(12459..12557,12705..12765,12821..12948,13104..13166) FT /db_xref="GOA:P36611" FT /db_xref="SWISS-PROT:P36611" FT /note="SPAC23C11.08, len:116" FT /gene="php3" FT /gene="SPAC23C11.08" FT /product="putative CCAAT-box binding factor; required for FT growth on non-fermentable carbon sources; similar to S. FT cerevisiae HAP3" FT /protein_id="CAB11161.1" FT /translation="MSADGLDYTNLLPIANVARIMKSALPENAKISKEAKDCVQDCVSE FT FISFVTGEASEQCTQEKRKTITGEDVLLALNTLGFENYAEVLKISLTKYREQQARSASM FT KETKQSRSEEPQ" FT misc_feature join(12492..12557,12705..12765,12821..12894) FT /note="Match to PF00808 CBFD_NFYB_HMF, Histone-like FT transcription factors (CBF/NF-Y) and archaeal histones. FT Score 46.59" FT misc_feature 12558..12563 FT /note="gtatgc, splice donor sequence" FT intron 12558..12704 FT /note="intron confirmed from EST" FT misc_feature 12686..12704 FT /note="ctaatgtctgactttttag, splice branch and acceptor" FT misc_feature 12766..12771 FT /note="gtatgg, splice donor sequence" FT intron 12766..12820 FT /note="intron confirmed from EST" FT misc_feature 12806..12820 FT /note="ctgaccatataatag, splice branch and acceptor" FT misc_feature 12949..12954 FT /note="gtaagg, splice donor sequence" FT intron 12949..13103 FT /note="intron confirmed from EST" FT misc_feature 13088..13103 FT /note="ctaacatctactctag, splice branch and acceptor" FT 3'UTR 13167..13556 FT /note="mRNA from SPRNAPHP3 X75072" FT mRNA 13524..13562 FT /note="mRNA from SPRNAPHP3 1164 1202" FT misc_feature 13556 FT /note="poly A attachment site" FT CDS 13980..16859 FT /db_xref="GOA:O13914" FT /db_xref="SWISS-PROT:O13914" FT /note="SPAC23C11.09, len:959, SIMILARITY:Saccharomyces FT cerevisiae, SYAC_YEAST, alanyl-tRNA synthetase, FT cytoplasmic, (958 aa), fasta scores: opt: 3840, E():0, FT (59.4% identity in 955 aa)" FT /gene="SPAC23C11.09" FT /EC_number="6.1.1.7" FT /product="putative alanyl-tRNA synthetase, cytoplasmic; FT similar to S. cerevisiae ALA1" FT /protein_id="CAB11162.1" FT /translation="MTAESEVVNWPANEIRRTFLKYFEDHGHTIVPSSSVIPYDDPTLL FT FANAGMNQFKPIFLGTVDPSSDFAKLKRACDSQKCIRAGGKHNDLEDVGKDNYHHTMFE FT MLGNWSFGDYFKKEAIAMAWDLLTNVYGLKKDQLYVTYFGGHEESGLEPDLEARQLWLD FT IGIDESRVIPGSLKDNFWEMGDQGPCGPCSEIHYDRIGNRTVPELVNMDDPNVLEIWNI FT VFIQFNREKDGSLRPLPNRHVDTGMGFERLVSVIQNKTSNYDTDVFSPIFAKIQELTNA FT RPYTGKMGDEDVDGIDTAYRVVADHVRTLTFAISDGGVPNNEGRGYVLRRILRRGARYV FT RKKFGVPIGNFFSRLSLTVVEQMGDFFPELKRKVDDVRELLDEEEESFSRTLDRGEKMF FT EQYAAAAKKTPSKTLQGNDVWRLYETYGFPVDLTHLMAEEAGIKIDEPGFEAAQARSKE FT ISKQASKGGSSGDDLLVLDVHALGALSKMDDIPETDDVFKHNSVSLKSVIKGIYHKGGF FT QKSTEGFNSGEQLGLLLDRTNFYAEQGGQEYDTGHIVIDGVADFRVTNVQVYAGYVLHT FT GFLEYGNLTVNDSVVCEYDEIRRWHLMNNHTVTHILNLALRNTLGDGIDQRGSLVSQEK FT LRFDFSYKSSIPIDKLLLVENYCNNVIQDNLSVYSKEVALSKAKEINGLRAVFGEVYPD FT PVRVVCIGVDIDTLLQEPKKPDWTKYSIEFCGGTHCDKSGEIKDFVILEENGIAKGIRR FT IVAVTSTEANRVSRLANEFDARIAKLEKMPFSPAKEAELKKISVDLSKLVVAAVRKHAM FT KERIAKITKQVQEHVKAINAAEQKEVVNVVTEYFKENPDMSFVVAKVPISANPKALSFA FT LTYAKKNLKDKSIYLLASDDTKVAHACLVSPEAMKKLTPQEWSQKVCHSIGGRSGGKGD FT TCQGVGDKPLSIDVAVEEAIEFFQGKLTI" FT misc_feature 14019..16817 FT /note="Match to PF01411 tRNA-synt_2c, tRNA synthetases FT class II (A) Score 1947.94" FT misc_feature 14715..14744 FT /note="PS00339 Aminoacyl-transfer RNA synthetases class-II FT signature 2" FT 3'UTR 16860..16968 FT /note="mRNA from spc10297" FT CDS join(17402..17522,17562..17660,17708..17906,17958..18120, FT 18164..18379) FT /db_xref="SWISS-PROT:O13915" FT /note="18/6/2002 found 3 additional C-terminal exons by FT eye; val" FT /gene="SPAC23C11.10" FT /product="conserved hypothetical protein; similar to D. FT meanogasta CG16790; similar to Mus. musculus Q91W78; FT similar to human Q9BQ65; no apparent S. cerevisiae FT ortholog" FT /protein_id="CAB11163.2" FT /translation="MSLVCYESSSSGEDDDETISDNPRMLKVPKLQESFHELYKKKPKT FT FDSPEFHEGRIRGQKHIEGLWFVQTYLEVDLSKKVKKGIREFLNSQSRFQSLLCSEHNV FT PRRLHLSISENYRINYSTKNQLVHKWEQYTNNLNYRTLKFRLGKMCLLFNDEKTRMFLA FT FECKFSDENYKDLISHASDCMKEFTNRNLREDFLLHISFASSLTNEDEYQNWVSQDRES FT HFFKTMNEIINTKIQKDQFSESFIVDSLKLSIGHLIFTFPFCK" FT misc_feature 17523..17528 FT /note="gtaaga, splice donor sequence" FT misc_feature 17542..17561 FT /note="ttgataactcatattcttag, splice branch and acceptor" FT 5'UTR 18815..18931 FT /note="mRNA from SPCKICAAA L29508" FT CDS join(18932..18977,19038..19318,19477..19789,19851..20152, FT 20246..20302) FT /db_xref="GOA:P40231" FT /db_xref="SWISS-PROT:P40231" FT /note="SPAC23C11.11, len:332" FT /gene="cka1" FT /gene="SPAC23C11.11" FT /gene="orb5" FT /EC_number="2.7.1.37" FT /product="serine/threonine protein kinase; casein kinase FT ii, alpha chain; involved in cell growth regulation" FT /protein_id="CAB11164.1" FT /translation="MNQTEAAPVVSVSRVYAHVNEEMPREYWDYENMQEVFGYQDNYEI FT IRKVGRGKYSEVFEGLNVLNNSKCIIKVLKPVKYKKIKREIKILQNLAGGPNIISLLDI FT VRDPESKTPSLIFEFVDNIDFRTLYPTLSDYDIRYYSYELLKALDFCHSRGIMHRDVKP FT HNVMIDHKKRKLRLIDWGLAEFYHAGMEYNVRVASRYFKGPELLVDFREYDYSLDIWSF FT GVMFAALIFKKDTFFRGRDNYDQLVKIAKVLGTDELFAYVQKYQIVLDRQYDNILGQYP FT KRDWYSFVNRDNRSLANDEAIDLLNRLLRYDHQERLTCQEAMAHPYFQVLK" FT misc_feature 18978..18983 FT /note="gtacgt, splice donor sequence" FT intron 18978..19037 FT /note="intron confirmed from EST" FT misc_feature 19024..19037 FT /note="ctaattagatttag, splice branch and acceptor" FT misc_feature 19118..19318 FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 56.38" FT misc_feature 19319..19324 FT /note="gtaaga, splice donor sequence" FT intron 19319..19476 FT /note="intron confirmed from EST" FT misc_feature 19463..19476 FT /note="ctaatattttatag, splice branch and acceptor" FT misc_feature join(19543..19789,19851..20152,20246..20287) FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 126.24" FT misc_feature 19790..19795 FT /note="gtaagt, splice donor sequence" FT intron 19790..19850 FT /note="intron confirmed from EST" FT misc_feature 19836..19850 FT /note="ctaaccaaactttag, splice branch and acceptor" FT misc_feature 20153..20158 FT /note="gtaagt, splice donor sequence" FT intron 20153..20245 FT /note="intron confirmed from EST" FT misc_feature 20232..20245 FT /note="ctaacttagcatag, splice branch and acceptor" FT 3'UTR 20304..21001 FT /note="mRNA from spc08605" FT CDS 21573..21815 FT /db_xref="SWISS-PROT:O13916" FT /note="SPAC23C11.12, len:80" FT /gene="SPAC23C11.12" FT /gene="hcn1" FT /product="anaphase-promoting complex (APC); high copy FT supressor of cut9; similar to S. cerevisiae CDC26" FT /protein_id="CAB11170.1" FT /translation="MLRRNPTAIQITAEDVLAYDEEKLRQTLDSESTTEEALQKNEEST FT RLSPEKKKIIRERRIGITQIFDSSMHPSQGGAAQS" FT CDS join(complement(23101..23234),complement(22340..22826)) FT /db_xref="SWISS-PROT:O13917" FT /note="SPAC23C11.13c, len:206, SIMILARITY:Saccharomyces FT cerevisiae, YJ9B_YEAST, hypothetical 23.7 kD protein in FT nmd5-hom6 intergenic region., (209 aa), fasta scores: opt: FT 737, E():0, (59.0% identity in 200 aa)" FT /gene="SPAC23C11.13c" FT /product="putative xanthine phosphoribosyltransferase; FT similar to S. cerevisiae XPT1" FT /protein_id="CAB11165.1" FT /translation="MDPVRLYYSYNDIHKMCAQQAEKILETFRPDVIIAIGGGGFIPAR FT ILRTFLKKKGSKNIPIQAIGLSLYEELVSDSPEEVPGLEVKRTQWLDFSTLGMVDLVGK FT NILIVDEVDDTRTTLHYALRELQRDVAEQAKKLNREGEKTTFGIFVVHNKVKPKNAQLD FT KEILDKYYFTGCNTPDCWIMYPWEAQDIEEHDSHVAKMGDLKP" FT misc_feature complement(22827..22838) FT /note="ctaatataacag, splice branch and acceptor" FT misc_feature complement(23095..23100) FT /note="gtaagt, splice donor sequence" FT 5'UTR 25437..25589 FT /note="mRNA from SPD236" FT CDS 25590..26753 FT /db_xref="GOA:O13918" FT /db_xref="SPTREMBL:O13918" FT /note="SPAC23C11.14, len:387, SIMILARITY:Saccharomyces FT cerevisiae, Q06808, oxidative stress resistance., (429 aa), FT fasta scores: opt: 1084, E():0, (46.8% identity in 376 aa)" FT /gene="SPAC23C11.14" FT /gene="zhf1" FT /product="CDF metal cation transporter; involved in metal FT homeostasis (PMID 11886869); involved in zinc homeostasis FT (PMID 11886869); involved in cadmium homeostasis FT (independent of the phytochelatin detoxification pathway) FT (PMID 11886869); involved in cobalt homeostasis (PMID FT 11886869); localization endplasmic reticulum (IDA) (PMID FT 11886869); similar to S. cerevisiae ZRC1; histidine rich FT cytoplasmic loop (PMID 11886869); 6 predicted transmembrane FT helices" FT /protein_id="CAB11166.1" FT /translation="MFDLARQTRIILLLGIDVTFFFIEIITGYAIDSLALIADSFHMLN FT DIVSLLVALWATRLAHSTSHEPKYTYGWQRAEILGALSNGVFLIALCMFIFMEAIERFI FT EPPSVSNPTLMFFVGSLGLLSNFVGIFLFHDHGHDHPHTHTAQNYDFPEEDDIESVLPS FT TIVHRCNTSQQEVSHTHTQVADSATESSPLLSYTGNHNGAGTSKPVNNHGSIEQDAPKQ FT TKKRNLNMHGVFLHVLGDALGNIGVISAALFIKYTDYSWRFLFDPCISILLTFIILFSA FT IPLCKSAALILLQVAPQSIKLDDVSNLINHLDGVESVHELHIWQLSDVKLIATVHVCVT FT LPDDKGESYTKLTTDIRNVLQSFGIYDVTIQPEFANHPLLCDQGSSS" FT misc_feature 25779..26717 FT /note="Pfam match to entry PF01545 Cation_efflux, Cation FT efflux family," FT 3'UTR 26752..26864 FT /note="mRNA from SPD236 1 1428" FT CDS join(27350..27380,27427..27607,27686..30701) FT /db_xref="GOA:O13919" FT /db_xref="SWISS-PROT:O13919" FT /note="SPAC23C11.15, len:1075, FT SIMILARITY:Schizosaccharomyces pombe, YB6A_SCHPO, FT hypothetical 171.5 kD protein c12c2.10c in chromosome ii., FT (1522 aa), fasta scores: opt: 1282, E():0, (27.8% identity FT in 1170 aa), also some similar to, Saccharomyces FT cerevisiae, SIN3_YEAST, paired amphipathic helix protein, FT (1536 aa), fasta scores: opt: 785, E(): 0, (25.9% identity FT in 1036 aa)" FT /gene="SPAC23C11.15" FT /function="essential for cell viability and required for FT retroelement propagation in fission yeast" FT /gene="pst2" FT /product="sin3 family corepressor; similar to S. pombe pst1 FT (paralog); similar to S. cerevisiae SIN3" FT /protein_id="CAB11171.1" FT /translation="MEQTLAILKNDNSTLVAEMQNQLVHDFSPNGTALPELDIKAFVQK FT LGQRLCHRPYVYSAFMDVVKALHNEIVDFPGFIERISVILRDYPDLLEYLNIFLPSSYK FT YLLSNSGANFTLQFTTPSGPVSTPSTYVATYNDLPCTYHRAIGFVSRVRRALLSNPEQF FT FKLQDSLRKFKNSECSLSELQTIVTSLLAEHPSLAHEFHNFLPSSIFFGSKPPLGSFPL FT RGIQSSQFTLSNISDLLSQSRPDNLSPFSHLSNESSDFFKNVKNVLTDVETYHEFLKLL FT NLYVQGIIDRNILVSRGFGFLKSNSGLWRSFLSLTSLSPEEFLSVYNSACSDFPECGPS FT YRLLPVEERNISCSGRDDFAWGILNDDWVSHPTWASEESGFIVQRKTPYEEAMTKLEEE FT RYEFDRHIEATSWTIKSLKKIQNRINELPEEERETYTLEEGLGLPSKSIYKKTIKLVYT FT SEHAEEMFKALERMPCLTLPLVISRLEEKNEEWKSVKRSLQPGWRSIEFKNYDKSLDSQ FT CVYFKARDKKNVSSKFLLAEADILRSQAKLHFPLRSRSAFEFSFVYDNEIVLFDTCYMV FT CTYIVCNSPSGLKKVEHFFKNILPLHFGLEKDKFSIFLDQVFRGPDYDVNAPNIVGNKP FT VRRKRSNSITQLTEFVKQPKINGQRESRSAAAARKKEESGNKSQSNSQNSLSDESGNVT FT PVSKKQLSQPAAAIKASLKYPSHPDSLLEHQDHAGDTENEMHDDVDKEQFGYSSMYVFF FT RLFNLLYERLYELQRLEDQVSIIQQRIIPNPVSQKQKIWRDRWNDLSDVPDEKTHYENT FT YVMILRLIYGIVDQSAFEDYLRFYYGNKAYKIYTIDKLVWSAAKQVHHIVSDGKYKFVT FT SLVEQNSSASPKKNYDDFLYRLEIEKLLNPDEILFRFCWINKFKSFGIKIMKRANLIVD FT QSLDTQRRVWKKYVQNYRIQKLTEEISYKNYRCPFLCRNIEKERTVEQLVSRLQTKLLR FT SAELVSGLQAKLCLDSFKLLYLPRTEDSYIDASYLRLRDTDFLDCQNKRKQRWRNRWES FT LLKSVRGTSDNTAEVNFDADINALFIP" FT misc_feature 27381..27386 FT /note="gtacgt, splice donor sequence" FT misc_feature 27410..27426 FT /note="ttaaccaatgttgttag, splice branch and acceptor" FT misc_feature 27608..27613 FT /note="gtatat, splice donor sequence" FT misc_feature 27670..27685 FT /note="ttaacatgaacattag, splice branch and acceptor" FT CDS 31018..33069 FT /db_xref="GOA:P50528" FT /db_xref="SWISS-PROT:P50528" FT /note="SPAC23C11.16, len:683" FT /gene="plo1" FT /gene="SPAC23C11.16" FT /product="serine/threonine protein kinase; Polo family ; FT involved in bipolar spindle formation; involved in FT cytokinesis; similar to S. cerevisiae CDC5" FT /protein_id="CAB11167.1" FT /translation="MASVAIKEPKTAITPKKKSKASRLCFTPPTNLHNNKKNIFYTRYD FT CIGEGGFARCFRVKDNYGNIYAAKVIAKRSLQNDKTKLKLFGEIKVHQSMSHPNIVGFI FT DCFEDSTNIYLILELCEHKSLMELLRKRKQLTEPEVRYLMMQILGALKYMHKKRVIHRD FT LKLGNIMLDESNNVKIGDFGLAALLMDDEERKMTICGTPNYIAPEILFNSKEGHSFEVD FT LWSAGVVMYALLIGKPPFQDKEVKTIYRKIKANSYSFPSNVDISAEAKDLISSLLTHDP FT SIRPSIDDIVDHEFFHTGYMASTLPDEILHSMPIWPSSQSKSSFQRNLDFVASASGVGF FT GNSAGVEKNKPYALRTDEVDNDRILPSVLSPRDRVNPVMKIGPETKPVPSKLSTALHAA FT RKSTDGSLGSRVKVLREESQSFVPTKSAVTEQVEPIQLIRSLSANTVSRLSKVGNMKSD FT IWISVKKTALKIGMALEAHTHALTSEDADSEPVLFITKWVDYSNKYGLGYQLSDESVGV FT HFNDDTSLLFSADEEVVEYALHPKDTEIKPYIYPASKVPESIRSKLQLLKHFKSYMGQN FT LSKAVQDESFEKPKNSTSNTMLFMQHYLRTRQAIMFRLSNGIFQFNFLDHRKVVISSTA FT RKIIVLDKERERVELPLQEASAFSEDLRSRLKYIRETLESWASKMEVS" FT misc_feature 31138..31905 FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic prot FT ein kinase domain" FT misc_feature 31156..31236 FT /note="PS00107 protein kinases ATP-binding region FT signature" FT misc_feature 31492..31530 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature 31885..31914 FT /note="PS00142 Neutral zinc metallopeptidases, zinc binding FT region signature" FT misc_feature 32515..32718 FT /note="Pfam match to entry PF00659 POLO_box, POLO box dupli FT cated region" FT misc_feature 32827..33027 FT /note="Pfam match to entry PF00659 POLO_box, POLO box dupli FT cated region." FT CDS join(33948..34023,34080..35461) FT /db_xref="SPTREMBL:O13920" FT /note="SPAC23C11.17, len:485, SIMILARITY:Saccharomyces FT cerevisiae, Q06493, chromosome xvi cosmid 9642., (454 aa), FT fasta scores: opt: 1063, E():0, (43.5% identity in 418 aa)" FT /gene="SPAC23C11.17" FT /product="hypothetical protein; similar to S. cerevisiae FT YPR125W;" FT /protein_id="CAB11168.1" FT /translation="MKYPRTHIQFPSMLRNRLFKTPHQTGFQWRLGAPATGITIRNQPI FT RSYSGLRGNFLIDKRLSPVKFNKYSPSDIVFYNIGSSRLYSTETPTPSKVKEAPKQVAA FT EETKPTTVVKKPSIWQRVKGGVLHFWDGTKLLGVEIKISSKLVYKMAVGYELTRRESRQ FT LTRTLKDIGRLVPFSVFVVVPFAELLLPIAVKLFPNLLPSTFEDAKDKEAKKAQLRKTR FT NEVSNMLRSTLKSGKFTFSNETRESKEFRDFFQKVRTSGQSPSREELIEVCKYFKDDIT FT LDNLSRAQLVAMCRYMNLNAFGTDPLLRYNIRHRMRQIRRDDRAIYIEGINSLSIPELF FT NACNSRGIRTQGLSPAKLKEELSVWLDMRIKHGIPSVILMLSNAFSYGYNEGTYDSRWD FT ALQDTLASIPDELYHETVVDMPTKQVSNKERLEILREQEELIEEEAEHVAEHPDLAKKQ FT TEENKATSKPAVSAKSPESNIPKNERK" FT misc_feature 34024..34029 FT /note="gtaagg, splice donor sequence" FT intron 34024..34079 FT /note="intron confirmed from EST" FT misc_feature 34066..34079 FT /note="ctaacgttttgtag, splice branch and acceptor" FT 3'UTR 35462..35765 FT /note="from SPD117 D89117" FT misc_feature 35765 FT /note="putative polyA site" FT CDS join(complement(36216..>38391),complement(36086..36170), FT complement(35963..36045)) FT /codon_start=2 FT /db_xref="GOA:O13921" FT /db_xref="SWISS-PROT:O13921" FT /note="SPAC23C11.18c, len:780, SIMILARITY:Saccharomyces FT cerevisiae, MSH1_YEAST, muts protein homolog 1., (959 aa), FT fasta scores: opt: 1246, E():0, (36.6% identity in 806 aa)" FT /gene="SPAC23C11.18c" FT /gene="msh1" FT /gene="SPAC13F5.01c" FT /product="MutS family; DNA mismatch repair protein; FT similar to S. cerevisiae MSH1" FT /protein_id="CAB11169.1" FT /translation="SVTRVITPGTLIDENFMNPYESNYILTVVFDPNFFSSDISNQGTA FT EDKDCFADCKIGLSWLDLSTGEFFTQDSNLQRLAGDLTRISPREIVLDESLKSFTTHPI FT YSFIQERKYFLSYVENRYQSLDCWNKFLEKEIDPSFIKYCTKLEVTAGCTLISYIADRL FT QNSHPNIQPPIRVSLNEYMIIGESAMKGLEIRSSLYQNRYTGSLLHAINKTVTKSGSRL FT LTRRLCAPSTNIVEINNRLDLVEKFKLLPELCSKVINLLKKSNDTHRILQHLLMGRGNS FT YDLLKMADNFSITKEIHSLLSPLESSSAFRLLLLNMHPHDELKQLINNAVDENALMKQK FT INEEEETEVIAQEAEEILQDENAQVEIVKKSLSSEFDIRQSFKENWVVKSNFNNNLRKL FT HEKLQSLFASYDKLQEDLSKRLGKKATLRKSPAKLYYVHLKLSGNETIERFIKKFTQAV FT LFQSTKSTASFQLPGWTSLGMDLENTKLHIHQEEQRVLKSITDEIVSHHKTLRSLANAL FT DELDISTSLATLAQEQDFVRPVVDDSHAHTVIQGRHPIVEKGLSHKLIPFTPNDCFVGN FT GNVNIWLITGPNMAGKSTFLRQNAIISILAQIGSFVPASNARIGIVDQIFSRIGSADNL FT YQQKSTFMVEMMETSFILKNATRRSFVIMDEIGRGTTASDGIAIAYGCLKYLSTINHSR FT TLFATHAHQLTNLTKSFKNVECYCTNLSIDRDDHTFSFDYKLKKGVNYQSHGLKVAEMA FT GIPKNVLLAAEEVLTLLPNTSKPTSMK" FT misc_feature complement(36046..36057) FT /note="ctgacgctacag, splice branch and acceptor" FT misc_feature complement(36080..36085) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(36084..36176) FT /note="Match to PF00488 mutS, DNA mismatch repair proteins, FT mutS family Score 31.39" FT misc_feature complement(36171..36186) FT /note="ttaactcgatacacag, splice branch and acceptor" FT misc_feature complement(36210..36215) FT /note="gtaaga, splice donor sequence" FT misc_feature complement(36240..36836) FT /note="Match to PF00488 mutS, DNA mismatch repair proteins, FT mutS family Score 350.93" FT misc_feature complement(36612..36635) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop), [AG]. FT {4}GK[ST], info count = 13.8" FT misc_feature complement(37197..38390) FT /note="Pfam match to entry PF01624 MutS, MutS family, FT N-terminal putative DNA-binding domain," FT misc_feature complement(37410..37436) FT /note="PS00215 Mitochondrial energy transfer proteins signa FT ture" FT misc_feature 38266..38391 FT /note="nominal overlap with cosmid SPAC13F5, EM:Z99091 S. FT pombe chromosome 1" XX SQ Sequence 38391 BP; 12011 A; 6896 C; 6897 G; 12587 T; 0 other; gatcagtgct acttcatgaa cgattaaaac agcactgaat gtaaaaatta gtgtttatag 60 tttacctgtg aaggatttaa aattatagaa gaaaaaatag agtgaagtag ttttcagttt 120 gggttctact gtgttaaaaa gatagtaatt gtacaaaaat tgaaaaatca acgtcttgca 180 tttacgaatt tgaccaattt ttaataattt ttggcaatgg accaggaaat taggtcgaat 240 aattatgata tttcggtttc gacagtggag gacacgagtt ttgaagcaat ggatgattct 300 atattggaaa ttattgatga tgaagcacca gagattcagg gaaaacctaa agcaaatata 360 tcaacacatt tccgcaacat gctagcaatg tttgggaatt tcctttccct ggggtttttt 420 ttagtcataa tagttttagt aggaatcgcc tttgagattg gcggtcggtt ttgcggtttg 480 gtaagtttag gaatgaagtt atttcaacat ttctttcttt ctctttctta aaaaataaac 540 taacataaat ttaaaataga tacttacact tgcactagaa gtatactttt tctctactgc 600 tttgttgaag ctgtttgggc ttcgaaaaat tgctttaaca ttacatttct ttgaacctct 660 tttagttttt attctattaa taatagccct taatgcatca ccaagcatag agcagaataa 720 atatgcctct tttcttgctt ctgcttggaa cactgctcta ctacacttta ctcccctatt 780 taatttgcta gaaggaatgg cgtcgctttt agttgtacaa gctcttggcc atctaagccg 840 ttggttggtc cataataagt ccgaaaactg gatggtacgt atattttata cttttattta 900 tgcctacgtt tgttaactta aacgcagttc tttattttgc ttaatgctag tagtgccata 960 tcaatgagcc tctatctcct ctatcgtgta tcttcttttt ctatctccaa tcctaatgca 1020 ttaatgatcg gattttccct tgcaactgtg attgtaattt ctatttatgg tgttgcttct 1080 ggacgtgcaa atttatctga agcatcgcta atggtaattg ttatttcctt atttctgatt 1140 ttaacatatt tagtttttgt atattgcata caccgtatat atggtttgta ctgattttgg 1200 caatccaaac actagttctc ttgagaaacc aaagtttgat tatcttcctc ctaatatact 1260 tcaaaggtaa gttccaacat gttttactta ttcactatta ccaatttctt gctttttttt 1320 cgagcagtcg aattttaaca ttttttaaca gtgttcacta tctaatctcc actatatctg 1380 ctactttacc aaggacgctt tataatattg tactttttat ggtagcggct gctaagaccg 1440 tagcgccgag tgttttcgct acatttgctt ttcgcatatc agttatgtat gccgtaacaa 1500 gaattttacc tgcaatacaa aataacatca tctttctcga gtacagtcga acttctaaac 1560 agggtatgtg gagtattctt tctccatgta tacttattgc agtctataca aaccttctat 1620 tacagcactt atacccaaca ccctctttca cttctccagt gaatcaaata ttgtgttccg 1680 ctgaaatttg gcgttgggta agtgctattt taactctcct cttatacgcc attgaactag 1740 cttatagcaa agagtctgac acaggccagg ctcttgctag ccatttcaaa cttgactaat 1800 ctgcaattga ttttcctaag gttatttaat tcactcgttt ctcctttcat tttttacatc 1860 taattctagt ctacactgtt aatttttcat tacttgataa ttgaatataa acggcttagt 1920 ttacaagttt agaatttctg gttacatccc tgaatatact aggaagtcac taagaggtat 1980 ttgtcccaag tatatgtaag ttagacccat aaaagacaga agtatatccc ctgtcacatg 2040 attctaattt actacggaaa aactacttag actactaaaa ctaatatcat tttacgacgc 2100 agtaatgaga caaacaactt tttattaagt tcgtttaagc tctaggcttt tccttcttct 2160 catggaaaag agcagaaaga ccaacaccgg caaccttgac gaccttgaaa cggacaccgg 2220 gaatatcacc cttagccttg cccttacgac cgaaaccaga aagaagaact tcgtcgtttt 2280 catcaacgaa gttgagacaa ccatcgtggg gaacgaaagc ggtaactttc ttaccattct 2340 tgatcaactg aacacgaaca catttacgaa tagcagagtt aggttgctta gcttctacac 2400 caatcttttc gacaacgata cccttagcat gagacgatcc accgaaaggt gatgacttgt 2460 aagcggttcc caataagcgc ttcttgtaat gagcatcggc ccaacgctcc tcacggcgat 2520 gattgcgaag cttacgagcg gcgttcaatc ctgcgggttt tcccattttg tagtatagag 2580 gttgcggcga actgtgtgtt ggatttaggt gaacttagct ttatgtccaa aacagtcaca 2640 aaccctaccc ttcttatata atatagtacg caacgcttca ctaagtaaat tgttgatgcc 2700 catacttact aaaattttac tacattacaa aaaagaaaaa acatctaaaa caaaaaacat 2760 acgtcttttt gattattttg gaaaaaggag ttgcaagtac tttgcaaaag gtttggtgtg 2820 taatatttaa gctcaattgg tatttatttg tttcgtactt ggaatacttc caagatattt 2880 agtcaaagtt ttgtgagatt taaaaaaaaa aaaagatttg atatgactga acttataaat 2940 tccgagccaa cactcttttt gttcccgaat aaagaggatt caaagcaatt ggttgaaaaa 3000 gctattgagg ttttctcaaa tataaaaatc ccatctacaa gtcccatcca aacaattgtc 3060 acaaaaggat tagataattg gcaaatatat aaccaactag cattagctgc caagtatgca 3120 ttagatgatc tccctcaagt tgatgttgaa aacgaagacg aagaagaaga tagcattact 3180 tctttccagg atgaggatga tgaaacaagt catcaggaac tctctgacaa tagtgaaatg 3240 aacaatcggg atgatgctga tgatgaattt ttagggttct ctggtccaga aaatctagaa 3300 gatgtcgacg aaagttctgc cgaagatgtt tcaggagatg aagctgaaat tatgaatgaa 3360 gaaggacaac aaatcgaaca gaaaaaagac gcatttggac ttaatgatgg tttttttgat 3420 attgataatt ttaacaagca aaccttagct ttagaagagg aagcagtcga agagggtgtc 3480 ctcggcgatg aagatgacgg tattgacttg ttaatggatc ccgatgagaa tatggaagac 3540 tctgaagatg aatcaaatgg tcctcaggct gactccatta tgtacgaaga tttttttggt 3600 ccaaaaacag cggccggtcg ccgtgaacta aaaaagaaaa aggccgaatc caaaagaaaa 3660 agaacaagta aaccggattt caaaaatgat gtgcaacaaa atgttattga agaaaataat 3720 gagagctctg acaatgagta tgctaccttt gatcgagtga agaaagattt atttgctagt 3780 gacgaagaag acgatgtttc agctgatcaa ttatcttctt atgagcgcga taaagcccgt 3840 ttgactcagc aaattcgtga gctcgaggct gaaaacgttg ccaagaagtc ctggaccatg 3900 atgggggagg caacgtctaa aggacgacct tctaattcac tgttagacgt tgatttggaa 3960 tttgaaactg gtgctaaacc tgtccctgta caaacggaag agactactga gacattagaa 4020 gatttaatta aaaaccgaat tatttccaaa acatttgatg atgtacctaa acgcgcgcca 4080 gttgctgtta ctgaatttcg accaagcgaa ttattcgagt taaacgaaaa taagtctcag 4140 cgttctttag cagaagaata tgaagaagaa ttccttaaaa agagcaacgc cgacacatat 4200 aagagtgaag ctgataaaaa gaaagaaaaa gaacatgaag aaatcaaggc attgttttcg 4260 gaagtcagcc gcactttaga ttctcttgct tcttggcatt atgttccccc tcctcctgag 4320 tctactgttg aaattgtttc taatgcaccc actttagcaa tggaggacgt tcagccaact 4380 gctgcctctg acactatggc attggctcct caagaagttt ataaaccgtc taatgagaat 4440 cgtgaaggtg aaactattac tcggtcaggt atcgccattt catcgactga aatggaccac 4500 caacaaaagc aagcacgccg caggcgggtg cgtagaaaac atgctgagaa acgtaagcaa 4560 atggctgaga aaagaaggaa ttccggtact gaacaagtcg ttcgtcaatt atcaaaatcg 4620 aatgttgagg tcattggtaa aggaggtgag cgcaaaaagg ttgcaagtaa ttcaaacaaa 4680 tatcatccga ttgtttcttc aaatcagcta aagctttgaa gataaatttc ggtgttaagt 4740 gtgctagtca taatttttat aaacgtttgg ttttagtggg atcaataact atatattttt 4800 gaaattaatg caatttaata atttcttaga tatcattcgt attattcgta ccaataattc 4860 catgtatctt catagtcttt aaggcattta aaaggaactt cttcaacatt tgtaaaacct 4920 tcttctactg ttggcatttg aaaacgagat ttgaaagaat taaacgctat ctcgggaagt 4980 tgtttttgct agaattggtt aggaattctt ctaagtcttt ctaatgctcc aacaggtaac 5040 ttacgttatg gtgaatgtaa cggaaaacgt tgttgtgtct ggcaagttcc tcagatgact 5100 gaagatgaat gcagcgtata gggatctcaa attcttgggc tatgtcaatc cacatttttc 5160 gtgattctat tgtagggttt gtgttgtctg aaatcgcgta agtcgttgaa atgatcgagt 5220 acatacctat gacaaccgat ttttcttttt taagtgcctc tatggcagcc ttgatgcatt 5280 ttgatttcgt ttttaagatg tcttgattta ccctttcgta tccttgagtg acaatctgag 5340 attcagctaa agtactcttc ccagaagaag gaaacccaac taaaacaaca atttcttgat 5400 gctcggattt tttaaaatgg tatggatgtg aagaagaatt tcttacaagg taattctttg 5460 gatgaaatga ttcaaagttt ggaggcacaa atgaatgccc caagaaaaat tgctcgggcg 5520 tctcaaattt aatcccaatg ttttcagcaa actttaaatc agttgaatta tgatcacccg 5580 gacggcctgc agcatcacct acgtatttga tgaaagataa atctaaaggg tgaaaaatgt 5640 taataggcct tgataaatta caagcgtcaa ctcaccaatt gaacggttca cgtcttttaa 5700 aaaggaattc cacattcctg tcaatggttt tctaaactta tctttcaaga tggcagcata 5760 caatacaata ggtagatcta atgactcaaa aatagcacga atcttcatct gaaaggtatg 5820 tccggcagaa ggttttcttg gaattccgtt ttgattactg aaaataacaa gagaataatt 5880 gtcttggtat aaagccttca attttgggac aacgcttgga tgccaccagg tccagtcagc 5940 tgcatctttt gaaaatactc taccagattt agtttttatg agcgttccat ctaaatcaaa 6000 tgcaataaat tttttagtct tttttagttt tccatacttt gctatgtata atgaatcggt 6060 gatgctccat tgaatttcta ttttctgttg aaggcatgtc gaggatgaat cagaatcttt 6120 gttttgagag ccgtactttt ttgaggattt agacgatttt tcaaaatatg aagttaaaga 6180 ttcctggggg ggagactttc tttttttcga cgacatcgcg attgacgaaa tactaaatgg 6240 gacttggtaa ttgagttagc tatattataa ttgcatagca atgaaaatgg gtggtttcaa 6300 taacatactt aaaaatggat aacagatgaa aattttattt ttcgctctat tgaattttca 6360 attgtttttg atcaattaca taaaatgcct catatacaac aattagtgag aagatatatt 6420 atatcatata gtccttaatc gaagatttaa tatgtttact gacttgaaaa taattcttat 6480 tcgaagaaat ttagacaata aataacaaga aaattcttta atttattcgt ctaatttatt 6540 atttggcaac cattcaaaga tttcacaaat aacatatttg agacctacat cttattcatt 6600 aacaattgca tatctcgtta tttacgaaca ttagtttttt ttttttggta tcgtttaaaa 6660 ttaaaccgtt tatttttaaa caaaaaatga aggacatcgg caatattttg tttttatgta 6720 tgagcttttt tttgcattat tttttcgttt gtcatttatc ttttttagta gctgatctgg 6780 aatttaaaaa caaaaatttc cataattaat taatttaaat atttcgtata tttttatata 6840 aacattatgg cttctactgc atcagccaag aatttactga tcgcaaaatc agtattccac 6900 aagatccata tcgacagaaa agaaacctgc atacaaggct aataaatatc tttgattgtg 6960 tttaatataa aaaattgata aattctcgta aaacaattta attttaataa tttatttgtg 7020 ctaaattttt atcatgttgt ggaaatctcc tttactatca atcatttaat aaagtattgc 7080 taaagaaagt aactttataa cagtattacc ctatgtaaga ttcacaaatc catctttatg 7140 ctgtataaaa taaaaacatg cgatattaaa aatataaacc tgttccttag aaaattttat 7200 aaattaatat aagatttttt gtatacattg agttacaaat tttgtagcag atgttgcgaa 7260 ttagtgcaca ttgcaacctg tacttaacca aaaacacttt tcagtcatga gtgaatacac 7320 tacccgtgaa gttggcgctt tgaacacatt ggactaccaa gtctatgttg agaaaaatgg 7380 tactcctatc tcttcttggc acgatatccc cttgtatgcc aatgctgaga agaccatctt 7440 gaacatggtc gttgagatcc ctcgttggac tcaggctaag cttgaaatta ccaaggaagc 7500 taccttgaac cctatcaagc aagatactaa gaagggtaag cttcgtttcg ttcgtaactg 7560 ctttcctcac cacggttaca tttggaacta cggtgctttt cctcaaacct atgaggatcc 7620 taatgttgtt catcctgaaa ccaaggccaa gggtgatagc gatcctctcg atgtttgtga 7680 gatcggtgaa gctcgtggct acaccggcca agtcaagcaa gttaaggtct tgggtgttat 7740 ggcccttctt gacgagggtg agactgactg gaaggttatt gtcatcgacg ttaatgaccc 7800 tttagctcct aagcttaatg atattgagga tgttgaacgt catatgcctg gcttaatccg 7860 tgctactaac gagtggttcc gcatttacaa gatccccgat ggcaagcctg aaaattcctt 7920 tgctttcagt ggtgaatgca agaaccgtaa gtatgctgaa gaagttgttc gtgagtgcaa 7980 tgaagcttgg gagcgcctta ttaccggtaa gactgatgcc aagtctgact tttctttggt 8040 caatgtttca gtcactggat ctgttgccaa tgacccttcc gtttccagca ctattcctcc 8100 tgctcaagag ctcgctcctg ctcctgttga tcccagcgtt cacaaatggt tctacatttc 8160 tggctctcct ctttaagtag tagtatcaca ctataatata gaatatagac tatatctgcg 8220 acactacatt tttgaccgaa acaggactat atgcgattat cgtagtcagt aaatatgtga 8280 ataatgctac attttcaaat aaatggtaaa gcgacgtaac ataaatcaag cagtaaaacc 8340 tcatggcata cttaaataac ctacaatcgt tacacacata aatatacaaa ttaccaggtc 8400 cttaaacaat cgacataaaa caaaaatatc atttaactaa gcattaaaag gtcattcgct 8460 cctaattggg ccacccaccg tatataatct ctcccaaacg tttcataatt aaatcaccac 8520 catcatcact caaccacaca tcatggggag cattgttaac aatatcccaa actgtgcgct 8580 gagttaactt acttagctgt cgctgttcat ctggccactt tttgaaacgc ttcatgcttt 8640 ttcctgcact aataacgcta acaggaagat ctttgggtaa cacagattga gccgactgta 8700 actcatatct agagaaacta gggccggtaa gcgattcttc aattttactc ttaacccaac 8760 gatccgaggt ccatgaatac atgccgtaca ctcggtcttg acgagttttg cccataaaga 8820 ttgaaccaaa aatacggttg atccccaaag gtgaaagcca accgcgaaca aaaagaagaa 8880 agcgggatag gaactgaccg gaatccttca aggtctgaac agacccagca tcaacgaaca 8940 ctattccttt cacctcagat agatggcgag cggcaaatac attggagtaa acaccgccga 9000 ttccatgagc gacaagcaca tacggaccgc tgacatctgc ttgagcaagt gcttccgtta 9060 gcaaatccat gacaattcca acggaggatg gagaaccaat attgtcggac catcccattc 9120 ctgggcgatc ccaaacacaa acacgtgtat caggtgaaag gtaaggctta acatcatttt 9180 cataaccttc gaaatcctta ctttcctcat aaagatcagg agaggtatgt tgaagattta 9240 agagccattc tttgaaagga tgaactgaaa cctcaccacc ctctactaaa acagttgttt 9300 tgttgttgga agaagaactt ccaaagcatt ccaaatggac tcttgcttta ctatcggtaa 9360 cggtatacaa ctgaccagga gcagaaaggg ctccatcgta agcacgcata atgagtgtga 9420 cgagagtgtg gatggtcagg atggtcaaaa tgacggataa tatcgtagag gcagtaagac 9480 tgccaacttg tctccaaggc cacgttgatg gggaccaaga ccaataatac ccacggtgtg 9540 caattgcatc gtagtccgga tgttcctcct tgtattggcg gaaaagcata agatcagtaa 9600 tcacaatcca taggctcatt aagaaagccc aaagaacgaa agcgttgctt cgccatcctt 9660 ctctatgacg aagaattggg ctaagaaaaa cgactaaaac atcgatggct aaaaggaaac 9720 aaatgattcg ttgtgtaact ctttcgggcg catttggtga gtatacaaac ataatttgca 9780 tggctagtaa aatggcagct agcgcggtga agccaacggg cataaaaccc ggagataaat 9840 ggctaataat cgggatggag atgaaaatat taagaagtaa aaatagatgg catattatag 9900 taattaacag taatccaacc gaggtgctac gaatccaata aaagagaggt gtcaaagcat 9960 acgtatcagt gttttcagga acattgcctc tatgcgatcc cagaaacctg ggcagcagag 10020 ccgatctttc gttagcagct tctgcgttca cgtcttgaga agtattcatg gttctctacg 10080 ttaatttttc tttactcggt aaccaaatgg ggatggttct gaagtaagat ggttcttttt 10140 aaagataaat agaaaggaaa gaaaagaaaa agaaacgttc ttcactagaa acagtggatc 10200 acgggaattt gagtagaagg gaataaagaa acgaaacgaa acgaaaacta tatggattta 10260 taattagagt aacggcgtaa acaagatgga ctgttgtttt taaatcccag caaaaatata 10320 tataatcaca acagagaaat cgattttgtc acaactagat gtgacaataa aacaatttta 10380 ggtaaaaatc aaatgtttct gtttatgcag tagacaatta ccacaaaaaa aaatagaaat 10440 tgacttgata attgttgaaa aagtattatt tgcaatgaat acaagtcttt gcaatacttt 10500 tgaattttct tttaacaata gcttgactac caaactattg taggcaaatg aatttattat 10560 gtaaagaaat cttggttaag ttctatcctt ttgcggaccc ttcaccatca ctggctactt 10620 gccatatata ttataaactg ccattatgtt ctacgtaaat tagcctgcgt cgaggaaacg 10680 taatgaatgg gcggctcagc gttgtatgga aataagacta gttaagtgtc ctttagtaat 10740 gcactcgatt actctatgtg acgtcgagag gacggaagag taggaatgat ggtaaaggca 10800 aaaaacatat tcgttctttt gacaacacac agctcgcatc gccttcaatt acccttgcca 10860 atgttgcaag tgatgatggg tgagatggga tagaaagagg agcaaacttt taatctgata 10920 tatcattgat gtataggaaa tgagaaataa aaatacaact aggtttatag tgcattccac 10980 tgtataatat aaagattagg atagatacac atgacttttg aagtgcagaa gtatagtcaa 11040 gtagggaata tagttgagta gatgcgagtt gtagaacaaa acaattcagt atacgcaatt 11100 ttcccctacg ggaacatatt taggtatgcg tgcgaatgga gagtgaagat gaatgaaatg 11160 tagaaaaaaa aaacactgga ttgtcagttt tgccataaga tacatttact ttcttgttat 11220 tccatttttc tacgaatctt ctttgctagg ttatttttat taactttttc gcaaacacga 11280 ttttaataac attgaattcc tcttcagtta tcagatgtga acggtaaata ccaattgtga 11340 actatttcaa acgaacttaa tatttgctct gtaagttgta aaataaatgt ctcataatta 11400 tttcgctgtc agtttccaca atcgcttcta ctcttttttt atatttatat ttatattttt 11460 tttttgaatt aaattaattc atattattat ttatttttct tggttttcta atgatatgtt 11520 tatgatattt ataaaaggat ttatttattt gctttttgta tgaaggatcg tcgcttgaat 11580 gacaaaacac ttcttttgct agtctctcct ttcctcttgt ttaacgtata tcacgattat 11640 tttgtcagcg taaaagtgac atagggatta gatggcatcc cactttcttt ttactgggaa 11700 accttggctt caagagaaga cgcctcgcct tcaccttcat cccacttggg accttaaagc 11760 ttccaaaagt cttgctcgtt tcccttatac gccacttgaa agtcttttgg cccccatttc 11820 ggcctttcac cccacttacc taaatagcgc agccccgtcg aaggctcaga gccatccagt 11880 attgctcgcc gctggagtag gtggaatagt agttagatgc cccagtcgga aaccgatata 11940 tcgtaccact cgaattcagt atctcttgtt aatctcccac tttacaactg cactatttaa 12000 ataatattat aggccgatac agtcagtctg cgaattgctt gcaacctgta gaaacaaatt 12060 gctgtttctt ttgcaataac atagtgtttc tttatcgcaa taaccaacta ctgatttctt 12120 tccctattgg aagtagatag acgtttactt tcttttgtga agaagcagaa agttaacgtt 12180 aagccattac cctcgttcat tgctcaaaag gaggtcattt ctttttattt gatttgttcg 12240 tcttttagga tcttcatctc ctgctgaatt attggatttc tttttagttc cctccacaaa 12300 ggctcgagaa taggttatca gctgtcgatt tttgtcaagg atcgtgcttg ctagtagtca 12360 aaccaatttt agcggggttt gtgtacttat tttcgttatt tgaggtttct ctgctcgcca 12420 aaattaaatt atacaagtaa aagatacatt taattatcat gagcgcagac gggttggatt 12480 acaccaatct cctaccaatt gcaaatgtcg cgcgtatcat gaaatcggca cttcccgaaa 12540 acgccaagat ttccaaggta tgcatgattt gttgaattga gaaaaatcgc attgtcagtc 12600 tcttcgattg attgattgct agtgacggag taggtcgctg tgagtgcgtt cttctctttt 12660 gttttgtaat tttcatgttg cagtgctaat gtctgacttt ttaggaagct aaagactgcg 12720 tccaagattg cgttagtgag tttatttcct ttgttactgg tgaaggtatg gaatcaatag 12780 caaaagcctc atgtatagtt atttactgac catataatag catctgaaca atgcactcaa 12840 gaaaagagaa agacaattac tggtgaagat gttttattgg ctttaaatac ccttgggttc 12900 gaaaattatg ccgaagtttt aaagatttct ctcaccaaat acagagaggt aaggaaaaat 12960 tctttatttg aatggtgata cgtgtacttc tacttccttg ttggcttaga gatttaaatt 13020 gtctcaagca atgaaggcgc aacaattcat tcactcatac caaaatttca ttctcatagt 13080 cacttttcta acatctactc tagcaacaag caagatctgc tagcatgaaa gaaactaaac 13140 aaagccggtc cgaagagcct cagtaatttc cttatatatt ttgcattagc ggggttttcc 13200 ctgaaatatt tcctgacttt tgcagcgatc gtcgatcgcc ttatttgtta ttcctctctc 13260 tttttgtact ctcctgtttt atctctgttt atcttacaaa tgatgctaat ttacgaacta 13320 tgttaatttc tactttaacc aagtttcaaa gataagcact atattgccaa aatggcctgt 13380 tcatatttaa aacttcctta atgtcgtcag tataaattta gcaattacta ttgcctgttt 13440 acttaaagtg tattattgtg attatccctc attcgctttt gcttactttt tcattttgtt 13500 aatcctgcta ctgttaacct atatattatt ttgaaaaaaa tagcatttca tttttatttt 13560 tactcatttc gtctatttca ccgaaatcag cataagacac atatagtcat tcggttcatg 13620 gaaggattag ccgatgtttc cgtagtcata tacgtatcaa tcaataaatt ttcttattgt 13680 caggaaagtg tttaatcctg ctgtagctag tatgtaaatt accttctcag cgtacggcta 13740 tataatacca gggtcatttt ccgtccaccg attctaatag attccaccaa cttcgtatgt 13800 tagggattcg tgcctcgttt cccatctgtt tatctaaaat aactaattta aattgccgta 13860 ataagtttcg attaacacat caaagcgtta tcaatactaa gtcttcattg tttgcgcgct 13920 taaaaatttc aacccacact ccttcttatc ctttacctac actacaccgc agagacctca 13980 tgaccgccga atcagaggta gttaattggc ctgccaatga gatcaggcgt acgtttttga 14040 agtactttga agatcacgga catactattg ttcctagctc ttctgtaatt ccttacgatg 14100 accctacctt actttttgcg aacgctggta tgaaccagtt taaacccatt ttcctgggaa 14160 ctgttgatcc ttctagtgat ttcgctaaat taaaacgcgc ttgtgattct caaaaatgca 14220 ttcgtgctgg tggaaaacac aatgatttgg aggacgttgg taaagacaac tatcatcata 14280 ctatgtttga aatgttgggt aattggtctt tcggcgatta ctttaaaaaa gaagctatcg 14340 caatggcctg ggacctactt accaacgttt acggtcttaa gaaagatcag ttgtatgtta 14400 catactttgg tggccatgag gaatctggtt tggagcctga tttggaggct cgtcaactat 14460 ggcttgacat tggtatcgat gaatcccgcg tgattcctgg aagtttgaaa gacaactttt 14520 gggaaatggg tgatcaaggt ccatgtggcc cttgttcgga aatccattat gacagaattg 14580 gaaatcggac tgtcccagag cttgtcaaca tggatgatcc gaatgtttta gaaatttgga 14640 atattgtttt catccaattt aaccgtgaaa aggatggttc acttcgtccc cttcccaatc 14700 gccacgttga tactggtatg ggatttgaac gtcttgtgtc ggttattcaa aataaaacct 14760 ccaattatga tactgatgtc ttttcaccta tttttgctaa aattcaagag ctcaccaatg 14820 cccgacctta taccggcaaa atgggtgatg aagatgtaga tggtatcgat actgcatacc 14880 gtgttgtggc cgatcatgtt cgtaccctaa cttttgctat tagtgatggt ggtgtgccga 14940 acaatgaagg ccgaggctat gttttgcgtc gtattttacg ccgtggtgcc cgttatgtac 15000 gtaaaaaatt cggcgtgcca attggaaatt tcttttctag actttcttta actgtagttg 15060 aacaaatggg ggatttcttc cctgaactta agagaaaggt agacgacgtc cgggaactac 15120 ttgatgagga agaagagtct ttctctagaa ctttggatcg tggtgagaag atgtttgagc 15180 aatatgctgc cgccgctaaa aagactcctt caaaaacact acaaggtaat gacgtatgga 15240 ggctttatga aacctatggg tttcctgttg atttaactca tttaatggct gaggaggcag 15300 gtatcaaaat cgatgaaccc ggttttgaag ctgctcaagc tcgatctaag gaaatcagca 15360 agcaagcttc caaaggtggt tcttcaggag atgatcttct ggtgctggat gttcatgcac 15420 tcggtgcact ttctaaaatg gatgatatcc cagagactga tgatgttttt aagcataact 15480 ctgtatcatt gaagtcagtt ataaaaggca tatatcacaa gggcggattt caaaaaagta 15540 ctgaggggtt caactctggt gagcagctcg ggttgttgct tgatcgaact aatttttatg 15600 ccgagcaagg tggtcaagaa tatgatactg gtcacattgt tatagatggt gttgctgact 15660 ttagagtcac caatgtgcaa gtctacgctg gatatgtact tcatactgga tttctagaat 15720 atgggaatct cacggttaat gattcggttg tttgcgaata tgatgaaatt cgtcgctggc 15780 atttgatgaa caatcatacc gttactcata ttcttaatct tgctcttcgt aacacccttg 15840 gtgacggtat tgaccaacgt ggttctttgg tttcacaaga aaagctgcga tttgattttt 15900 cgtacaagtc ctcaattcct attgataagc ttctcttagt tgagaattat tgtaacaacg 15960 taattcaaga caacttgtcc gtgtattcaa aggaagttgc tttgagcaaa gccaaagaaa 16020 ttaatggatt gcgtgctgtt tttggtgaag tttatcccga tcctgttcgt gtcgtttgta 16080 ttggtgttga tatagataca cttttgcaag aaccaaagaa acctgattgg actaaatata 16140 gtattgaatt ttgcggtggt actcattgtg ataaaagtgg tgagattaaa gactttgtca 16200 ttttagaaga aaatggtatt gcaaagggta ttcgtcgtat tgtcgctgta acatcaactg 16260 aagccaatcg cgtttctcgt cttgctaacg aatttgatgc tcgcattgcc aaattagaga 16320 aaatgccttt tagtcccgca aaagaggctg aacttaagaa gatctctgtc gatctgtcaa 16380 aattggttgt cgctgctgtc cggaagcatg caatgaagga acgtatcgcg aagatcacca 16440 agcaagtcca agaacatgtt aaagctatca acgctgctga gcagaaagaa gttgttaacg 16500 tcgtcactga atattttaaa gaaaatcccg atatgtcatt tgttgtcgct aaggtcccta 16560 tttctgctaa tcccaaagcc ttaagttttg cccttactta tgctaagaaa aatttgaagg 16620 ataaaagtat ttacttgtta gcatctgacg atactaaagt tgctcatgca tgtcttgttt 16680 cacctgaggc catgaagaag ttaactccac aggagtggtc tcaaaaagtt tgtcacagta 16740 ttggcggtcg cagtggagga aaaggtgata cttgccaagg tgtaggtgat aaacctcttt 16800 ccatcgacgt tgcagtggag gaagcgattg agttttttca agggaagttg acgatttaag 16860 tttctacgtt attttgtact ctatctttca ttatcttcta cataggctca actttttgtt 16920 tgttttatag tccgagcatt ttaaaattgc tcaacaattt caatcattat acataaactc 16980 atcgtaggct taaacgtcga gtgtttactc aatgaacact tcttaatttt aagcgatagt 17040 ttgaaaatta caatttccca gccgcgtgtt attgtattat taagattatg tgtaaagcct 17100 gaagatcacg atttcctatt atttactgct agtctgtcac gctaatacag catacttata 17160 tgtacaagtc tgaacaaacc taccactgac ttcaagagtg aaaggatagg tttattgcag 17220 ttcatatgaa atcgggattc taagcaaaag cttatgtcta ttcgaataca tactaataac 17280 caaactatta caaaaatttt tgcatgaata tctattacta ttacaggcca tttctacacc 17340 attccttgag aaaagaaagt agccatcttt attatattaa taaaaaaaaa tagaagaata 17400 aatgtcttta gtatgttatg agagttcgag ctccggagaa gacgatgacg agacaatatc 17460 tgataatccc cgaatgttaa aagtccctaa gctccaagaa tcatttcacg aactttataa 17520 gagtaagaag gttttaatgt tttgataact catattctta gaaaagccaa aaacttttga 17580 tagtcctgag tttcatgagg gtcgaattcg tggacaaaag catattgaag gattgtggtt 17640 tgttcaaaca tatttggagg gtaataaatc aatttttatt taacaaaaag ttgacaatta 17700 tcaatagtgg atttgagcaa gaaagttaaa aaaggcattc gtgagttttt gaattcacaa 17760 agtcggtttc aatcgcttct ttgctctgag cataatgtac caagaagatt acatttaagc 17820 atatctgaaa actaccgcat aaattattcc actaagaacc aattagtgca caaatgggaa 17880 caatatacaa acaatttgaa ttacaggtat actcaggaca aataatccat actgttgaga 17940 ctgacatatt aaaaaagaac tttaaaattt cgactgggaa agatgtgtct actatttaat 18000 gacgaaaaaa caagaatgtt cctagctttc gaatgtaaat tcagtgacga aaactacaaa 18060 gacttaataa gtcatgctag tgactgtatg aaagagttta caaataggaa tttgagagag 18120 gtaagtaaag gttcaaataa gcgacaattt taacgccttc caggactttt tacttcacat 18180 atcctttgct tcatcgttga caaatgaaga cgaatatcaa aattgggtca gtcaagacag 18240 agagtcccat ttttttaaaa cgatgaatga aattattaat acaaagattc aaaaagatca 18300 attttctgaa agttttatcg ttgatagctt aaagttgtca attggacatc taatatttac 18360 ctttccattt tgtaaataat ttattaattg gggcgataat aatattatta caatactcgt 18420 ttacgaaaga atatgctcag cttcaaatca attggtctta ggaacacaaa aagtgatcat 18480 tagcaattgc attcagtttt gttacaaagc atgcggacta aaacgtatga aggaagaata 18540 atttcaaaaa aattccttat tagaagcttt agtatactca ttttcgtctt ctgtgatcgg 18600 attttgattg caacgtttat cagttttttg ttacatttct tctcactaga aaacaatatc 18660 ataactatat tttcacttgt ttggtttata aacttaagcc atatagcgca ttaacttgtt 18720 tatattgcta tattgcttgt aacggagctt aaaacacttt gttaattttc actaagcact 18780 ctctttgcac ttgcatacac aagacctgcc cttcaccagc tagcttgcta aacaaatttt 18840 ttgggttccg tttcatataa aggattttgc attaacatag agggagcact ctaagaaaaa 18900 aaaacgtgaa agctgaaagg tgctacttac aatgaaccag actgaagcgg ctccagtcgt 18960 ctcagtttcc cgggtttgta cgtattgtga agttcaaatt tataaaaaaa ggataacaaa 19020 tgactaatta gatttagatg ctcatgttaa tgaggagatg ccccgtgaat actgggacta 19080 cgagaacatg caggaggtat ttggatatca ggacaattat gaaattattc ggaaagtagg 19140 aagaggaaaa tatagtgaag ttttcgaagg attaaatgtc ttgaacaaca gcaaatgcat 19200 catcaaagtc ctaaagcctg taaagtacaa gaaaatcaag cgtgaaataa agattctaca 19260 gaacttggcc ggaggtccta acattatctc actgcttgac attgtccgcg atccagaggt 19320 aagaataaaa aaaaaaagct ttttgtattg aatcgtcttg aaacttgaag gagaagaaat 19380 tttgtgcttt tccgtctatt gagtttatac gactctggct tttgaacgtt tgatatccat 19440 caaactattg tatttgtcga tactaatatt ttatagagta aaacaccatc tttaattttt 19500 gaatttgttg acaatattga tttccgtaca ttgtacccta ctctttctga ttatgatatt 19560 cgttattact cttacgagtt gctaaaagct ttggatttct gtcattctcg tggtataatg 19620 catcgtgacg ttaagcctca taatgttatg atcgatcaca aaaaaaggaa gttacggcta 19680 attgattggg gtctggccga gttttatcat gctggcatgg aatacaatgt tcgtgtagcc 19740 agtagatact ttaagggtcc agaactgtta gtagattttc gagaatatgg taagttgcat 19800 ccacttttgt taaatatatt tacgtttctt ttttcctaac caaactttag attactcctt 19860 ggatatttgg tcgtttggtg tcatgtttgc tgctttgata tttaaaaaag atactttttt 19920 ccgtgggcgg gacaattatg atcagctagt taaaattgcc aaagttctgg gaactgatga 19980 acttttcgct tacgtacaaa aataccagat tgtgctggac cgacaatacg ataatattct 20040 tggtcagtat cccaagcggg actggtattc ttttgtcaac cgtgacaaca gatcgcttgc 20100 caatgatgaa gcaatcgatc tgttaaatcg tttattacgt tatgatcatc aagtaagtta 20160 ccgaacctga aggtttttac aggatcttat acaatcactt atttttttaa gtggtatata 20220 ctgtatagtt actaacttag cataggagcg tttaacttgt caagaagcta tggcccatcc 20280 gtactttcaa gtactcaaat aagaactgag ggaagggact ataactcaat tatctctacg 20340 gacagccttt tcattactag ttcccttcat tttcataaaa atgaaccaaa tccaattcta 20400 gttttaattc tggttcatgt tttattattc ttttcttatt attagacttg agtattcctc 20460 ttcatttacg tcggtgataa tttaagctaa tatttcttgc ccaaacgtta tcatctccca 20520 cacgattcct cgaaacggtt cttgcataag tacatcctac tataatattg ctttcacgtg 20580 gcggagcctt cccactactt tttccccgta cctactcgtt agacacttgg tctacatagt 20640 gtctgtgtct attgctttcc cttactcaaa ttagagtttt ttttattttt aaatgctatc 20700 gggcttacta aacaggttcc aattctatag ttttctttaa tactttaaac gagtttttac 20760 ctctttaggt acctaacagc tttattaata gtaagtaact ctgcgtatta tgcataatga 20820 atgcaatcta aagaagcgat ggaaatgaat atgcgatatt tcatgaatga aaagtaaagc 20880 cttaattaga gagcaacctt acaaaacctc ttattctgta gcgttaatct tgcgcagctg 20940 ctcatcctga acttgttgaa gttcaatgct caaaacaatt gccttttgta aattcatttt 21000 actgtattta acacatatta gaattcatca tattaaaaaa aatgataatg tcataaacta 21060 gggatgaact tacaggaatt cgcatttatt caacactgat tccaaatgaa acagtatttg 21120 cttttgaacc tcagtcagca tgccaaaatt tgcaccaaaa tctaattcaa aagaatgtgt 21180 tgtgatcttt gaattcggaa aaaacaactt tacttatctt acttggtaaa gtatattgtt 21240 taaccaggca aatttgttaa aaaaggagta gtttacctct cgctttatgc gtatttatgg 21300 taaaacaagt ataaaacact ataacgcggt agctcaatct ctcgctttta gaaaatactt 21360 tacgctacga tccaaataaa tgggttaact tgtgtatcgt ctaccaaaac aacacctaaa 21420 acagcgtgtt ttatcattgc attgcaacta aggtgagttt ctttcttcct ctcttgcttt 21480 ttcatccttg aatgtaaata aaattcaatc aagctgaata taaatttaat aacagaccac 21540 atttgtgtac tacgtttgtt agtatctcca acatgttacg aagaaatcct acggcaatac 21600 aaattactgc tgaagatgtt cttgcatatg acgaagaaaa gctaagacaa acgcttgatt 21660 ccgagtcaac aacagaagaa gcattgcaga aaaacgaaga gtcaacacgt ttatcgcctg 21720 aaaagaagaa aattattcgt gaaagaagga ttggaattac tcaaatattt gattcttcaa 21780 tgcatccttc ccaaggtgga gccgctcaat catagaccgt gaaactaaat cataattaaa 21840 tcatcaaata atcgttagcc cacatttttt cgatttgcac tgttttgtta gcatttcaca 21900 cctgcctcca tactgctgat ctttacatat aactatttta atcggccatc ataatatgga 21960 ctacactgtc tatgttaatt taattagtaa gatatacatc gattgataga acagtgaagt 22020 tttcgttaaa caatgaccag tctcattaac tttaatcttg catacattta tcctaatgct 22080 tcactccatc aattattcaa cttaaattct tacccatatc aaattgtcaa gctatttcat 22140 ttctattgtt accaagagta tttataaagg ttattcgcaa aatttatcaa atctatatat 22200 gtatatgcat gtcgacaaaa aaaaaagtgg gctttaggaa agaggtgaag gcgtgtggat 22260 caaatagata gtttgcgaat taataattaa gagtaaattc gaaaagctca ctatagttta 22320 caaaacacga gactccaatc tatggcttca aatcccccat ttttgcaaca tgactgtcat 22380 gctcctcaat gtcttgagct tcccaaggat acatgatcca gcagtcggga gtattgcaac 22440 cagtaaagta atatttatcc aaaatctcct tatccaattg agcatttttt ggtttaacct 22500 tattatggac aacaaaaata ccaaatgtgg tcttctctcc ttcacggtta agcttcttag 22560 cttgctcggc aacatctctt tgaagctcgc gaagagcata atggagagtg gtacgagtat 22620 catctacctc gtcaacaatt agaatgttct tgccaacgag atcaaccatt ccaagagtac 22680 taaaatcaag ccattgagtt cgcttaactt caagcccagg aacttcttca ggggaatcag 22740 aaacaagctc ttcatacagg ctgagaccaa tggcttgaat gggaatattt ttgcttcctt 22800 ttttcttaag gaaagtacga aggattctgt tatattagca aatgttaacc atatgaagat 22860 aagaagagca aggaatttga atgcaccacg atggattctt gggctcaatt gaaaatgcag 22920 gtaaacgatg cgtccttttg aaaagatcat acataaaagc cttaaaatcc ttatcgtgga 22980 taagcattgt taaaatcaat catttgtgaa atcacaaaga tgctgccatt caaattttaa 23040 cgcagtaggc cgttatagga agcgcttctt cctgttatct tctttatttg ttcaacttac 23100 ctagccggaa tgaatccacc acctccaatg gctataatca catcaggacg aaaggtttcc 23160 aaaatttttt ctgcctgttg agcacacatc ttatgaatgt cattgtagct gtaataaaga 23220 cgaacgggat ccataataac ttaagaacaa aatgaaacaa ccaaaaaatg aagggaacga 23280 taaaggtgta aacgtgaacg ggggaaatac gttcttttga tatttatgta cttttgacaa 23340 tttaagcgtt ccttaaggta atctcgttaa attactgata ggaaaaagtc actaacccta 23400 ccctctatgg tggttagtta gggatattct aacaccgacc agacggtgtc tagcaaagaa 23460 tatgatgttt aaaacgattt cagttatcta tgaaggccat tacatatgta aatgttcttt 23520 atattgattt tctagatgtt taatactttt caaaacccat catttcgttg ttaaaaatat 23580 attaaaaggt atatcagcta gcatgtctga taagatttat tatatgtata taatgcttta 23640 ggtttcaatt ttactgttta ctttttgtat aattatagca aaattaatat agctcaattt 23700 ttgcctgggc aattaactgc ggtacattac tcaaatgtac tcgtaacaag aaaggttttg 23760 gattattcag tgccgtttga agaaccgatg cagtcagtca tcacataggt gtctcatccg 23820 aagcctcgta gttctgggaa ggattagacg cattacctaa aaaacggtac aagggggatt 23880 gtacaagtag atagtgcagc gaatttgtaa atatctaatc acttgtaacc agccaaaaag 23940 tagataacgc agcatacgta gtaaatatcg agacacatgc ttacttcaat cttacactaa 24000 ctggtgattt ttagatatgg tggagaccat gagttattga taaatgaact atttatttgt 24060 catttgagaa tgaaaagaag gaaatataat gaacaggatg attgagaatg ttcttattct 24120 ttttgtttta ttaataatca tgtatatata tatatatata tataaaaatt tttttaaaag 24180 aaaaccctct gacatcaggc tttcattcaa aacattaaca atgctgctat gttgacagta 24240 taattatgaa aagctcttca acatcactag attttccttt tagaaagagt tttattttcg 24300 aagcatttct tttttgtatg cattcactca taatattaaa attacttgat atatttagct 24360 tattactagc gaaatctggg gagagagaat gctcgtttat gaacgaagat cataaaacat 24420 tgtaagtttt gagaacaaac cactgctata aacaacaaat agaaagacct ttttaatata 24480 ttttatggcg tttaatcaaa ttattaagca aacccagtaa tagctaaaaa tagttgaaac 24540 atctaggatc attttcaatt ccttatttat ttacttctaa acagccgttc ggccaagttt 24600 ctgtgagcta caagaaatga tggtatcttt caataaacaa tgattggcgt tgcataaagc 24660 aagcgtatga atggaatatt gagctattaa aaataatata aatatgcaat ttcaaacgtt 24720 ttcggctttt aaaagtggaa cgtggcacat ttaatcaacg taaatcattt tttttttacc 24780 tatagaagtt tacccaaaaa ttgataccaa gtattagctt tattaactaa ttacttttgg 24840 taaagcggta gaacctattc gacgaaatat caatcaaatt accaagtacg atcttgtcgc 24900 tcactcatta cccaaaaaat catagaaagg acgatccaaa tatgtgtgca tattgcttat 24960 aattaactcg tttattactg cgatactctg taattcgttg tatctgatta cgaataataa 25020 tagtcacttt tacgatatca attattatca gataaatatt ttcgatcgca aaatttgatc 25080 ttctaactat tttgactaat ttgtgcgttt attcttaaca ccgaattgaa agaaaatttc 25140 aaaaggtagt ctttgttagt tccttttgtg gtaaacgcga ttagtggcca gtcacttaca 25200 aaactttgtt aaagcagact aatagtagtc aacgtgtgat tttatttttt cttcaccgct 25260 tacttctcaa aagcctcctt tttaatttac tatcaaaaac ggcagttttg gcagtttttt 25320 gaaggtttat tggtttaatt aatttattct gtaaaaacaa ggaaagcaaa attacagata 25380 tttgattctt tagattttct taaaccctct cgcatcttcg tcttattttg gctttttttt 25440 ttgttaaata tagcaagttt gcgcctcttt tatttaaatt catttttaaa aagccacctt 25500 tcattctaaa tttaccttat tcctttttct ccctgtgaaa ttcaaccctt accatttttt 25560 tgaaattggt gacttttcgt tttcaaacta tgttcgacct cgcaagacaa actcggatta 25620 tccttttatt aggtattgat gttacttttt tcttcatcga aattattact ggttatgcga 25680 tcgattcact tgccctaatt gctgattcat ttcatatgtt aaatgacatt gtcagtttac 25740 tggtcgctct ctgggctact cgtctagcac attcaacatc tcacgaacca aaatacacat 25800 atggctggca acgtgcagag attttaggtg ctttgtcgaa cggtgtattt ctcattgccc 25860 tttgcatgtt catttttatg gaagccatag agcgcttcat tgagcctcct tctgtcagca 25920 atcccaccct tatgttcttt gttggttctt taggtctgct aagcaatttc gttggtatct 25980 ttttatttca tgaccatggt catgatcatc ctcacaccca taccgctcaa aattacgatt 26040 ttcctgaaga agatgatatt gaatccgttt taccttcgac tatcgttcat cgttgtaata 26100 ccagtcaaca agaagtcagc catacacaca ctcaagtcgc agactctgct accgaatctt 26160 ctcctttatt gagttacact ggtaatcata atggtgctgg tacttcaaag ccagtcaaca 26220 accatggcag tattgaacaa gatgcaccaa aacaaacgaa gaaacgaaat ttgaatatgc 26280 atggtgtctt tcttcatgtc ttgggtgatg ctctcggtaa tattggtgtt attagtgctg 26340 ctttattcat caagtatact gactattctt ggcgtttcct ctttgaccca tgcattagta 26400 tccttcttac tttcattatt ctttttagcg caattcctct ctgtaaatcc gctgctctca 26460 tcttattaca agttgctcct caaagcatca aactggatga tgtttccaac ctaattaatc 26520 atctagacgg cgtggaatct gttcatgaac tccacatctg gcagctttcg gacgttaaat 26580 taattgccac tgttcatgtc tgcgttacac ttcctgatga taagggagag tcttatacaa 26640 agcttactac ggatatccgt aatgtccttc aatcttttgg tatatatgat gttaccattc 26700 aaccagaatt cgccaatcat ccgcttttat gtgaccaagg ttcctcgtct tagtttgcga 26760 acattataaa tttaacgtgg ttaatctatt gtgtcacatc ttttgattta ttcttgaggt 26820 aaaattttat attgaatgtt tactttgttt catttttaaa gcgtaatttc ttctgccatt 26880 cctgttcgta tttaaaaact ttatttcacc atcttggttg tttgttttgc gaatgcactt 26940 aagtaaagta gtcgacaact taactttgaa agtagatagt tttcgatttc ttattcttga 27000 tgaagacgat gcatagtttc ggttttatta aatctctatt attcttagaa aataatgttt 27060 agatgtagtg tttaattatt taaaaggaat attttttaac aattatattg ggtttgattc 27120 ttctcgttag tattttttct aaagtattcg ttgtaagtgt aaaacaccat ccaatgtggt 27180 atttgtgttc atgtcttgat aaatcatttg aactttggct atcagcgtca gttcatgtaa 27240 tgcgttgacg agtttgtgcg cttagttgca tttgccgttt cccaaatcat cacctccaaa 27300 ataaacgaga tcgtattcct agtcatttga tggttaaaga tcaaaataca tggaacaaac 27360 actagcgata ttaaaaaatg gtacgtatca atttaataca taactcattt taaccaatgt 27420 tgttagacaa ctcaacgtta gtggccgaga tgcagaatca attagtccat gatttttccc 27480 ctaatggtac cgcactcccc gagcttgata taaaggcatt cgttcaaaag ttgggtcaaa 27540 gactgtgtca tcgtccttat gtttatagcg ctttcatgga tgttgtgaag gctttacaca 27600 atgaaatgta tatatggctt atttactgag ttgctttgag atagctcttt ttttattact 27660 attcacttat taacatgaac attagtgtcg attttcccgg gtttattgaa agaatatctg 27720 taatcttaag agattaccca gatcttttag aatatttgaa catctttttg ccctcgtctt 27780 ataaatacct tttatcgaat agcggtgcca acttcacatt gcaatttacc accccatctg 27840 gtccagtttc tacaccgtct acttatgtag ctacttacaa cgacttacct tgtacctatc 27900 atagagctat aggatttgtt tcacgagttc gacgagcatt attgagcaat cccgaacagt 27960 tctttaaatt acaggatagt cttcgtaagt ttaaaaactc tgagtgttcg ctttctgagc 28020 ttcagactat tgtaacgtct ttgctagcgg agcatccatc tttagcccac gagtttcaca 28080 actttttacc aagctccatc ttttttggga gtaaacctcc tctaggatcg tttccattaa 28140 gaggaattca gagttcccaa tttacgttga gtaatatttc tgatttgctt agtcaatcaa 28200 ggccggacaa cctctcacca ttttcacatt tatcaaatga gagcagtgac tttttcaaaa 28260 atgtgaaaaa tgtacttacc gatgtagaaa cttaccacga atttttaaaa ctcctgaatt 28320 tgtacgttca agggataatt gatagaaata ttctggtgag tcgtgggttt gggtttctta 28380 aatcgaattc gggactttgg agaagctttt taagccttac tagtttgagt ccggaagagt 28440 ttttatctgt atacaattcc gcttgctcag acttcccgga atgtggcccg agttaccgat 28500 tgcttcctgt cgaagaacgc aatatttctt gcagcggtag agatgatttt gcatggggta 28560 tacttaatga tgactgggtc agtcatccaa cttgggcatc tgaagaaagc ggtttcattg 28620 ttcagaggaa aacgccttat gaagaggcaa tgacaaagtt ggaagaggaa cgttatgaat 28680 ttgatcggca tattgaagct acttcctgga caatcaagtc tcttaaaaaa attcagaacc 28740 gtataaatga attgccggaa gaggaaagag aaacatatac tctcgaggaa gggctaggtt 28800 taccatcaaa aagtatatac aagaaaacta ttaagcttgt ttataccagt gagcatgcag 28860 aggaaatgtt taaggccttg gaaagaatgc cttgcctcac attaccattg gtaatcagca 28920 gattagaaga aaaaaacgaa gagtggaagt ctgttaaaag aagtcttcaa cctggatggc 28980 gaagtattga gtttaaaaat tacgataaga gcttagattc acaatgcgtt tattttaagg 29040 caagagataa gaagaatgta tcttcaaagt ttctcttagc agaagccgac attctacgat 29100 cgcaagcgaa gctccatttt cctttgcgaa gtagatcagc tttcgaattt tcttttgtat 29160 atgacaacga aatagtactt tttgatactt gttatatggt atgcacatac attgtatgta 29220 actctccctc tggtttaaag aaagttgagc attttttcaa gaatatattg cctttacatt 29280 ttggtcttga aaaggataaa ttttcgatat tcctggatca agtttttcgt ggtcctgatt 29340 acgatgtgaa tgccccgaat atagttggta acaagcctgt acgtcggaaa agatctaatt 29400 ctataaccca gttgacggaa tttgtaaaac aacctaaaat caatggtcaa cgcgaaagtc 29460 gttcagctgc agctgctcgc aaaaaagaag aatccggtaa caaatcacaa tctaactctc 29520 aaaactcttt aagtgatgaa tctggaaacg taacgccggt ttctaagaaa cagctttcac 29580 aacctgctgc agccattaaa gccagtctca aatatccaag tcatccagat agtcttttgg 29640 aacatcaaga tcatgctggt gatacggaga atgaaatgca tgacgacgtc gataaagaac 29700 agtttggata ttcttctatg tacgtatttt ttagactttt taacttatta tacgaaaggc 29760 tttatgagct tcagcgtttg gaggatcaag tgtccattat ccaacagcgt ataataccaa 29820 acccagtatc tcaaaaacaa aagatttggc gcgataggtg gaatgatctt tcagatgtcc 29880 ctgatgaaaa aactcattac gaaaatactt atgtgatgat tcttcgatta atatatggga 29940 tagttgatca aagtgccttc gaggactatc tgcggtttta ttatggcaat aaagcctata 30000 aaatatatac tattgataaa ctcgtttggt ctgctgctaa acaagtccac cacatcgttt 30060 ccgatggaaa atacaaattc gttactagtt tagtcgaaca aaatagttct gcttcgccta 30120 agaagaatta tgatgacttt ctttatcgct tggaaattga aaagcttttg aatcctgatg 30180 aaattttgtt tcgattttgt tggataaaca aatttaaatc atttggaatc aaaataatga 30240 agcgagcgaa tcttattgtg gatcaaagtt tggatacaca gagacgagtt tggaaaaaat 30300 atgttcaaaa ttatcgtata caaaaactta ctgaagaaat atcttataaa aattatcgtt 30360 gtccctttct ttgcagaaat atagagaaag aaagaacagt tgagcaattg gtttcacgcc 30420 ttcaaacaaa gttattaaga tctgcagaat tggtttccgg attgcaagca aaattatgtt 30480 tagactcgtt taaattgctc tacttaccac gcacagaaga ttcttacata gatgcatctt 30540 acctgcgcct tagagatacc gacttccttg attgccagaa taaaagaaaa cagcgttgga 30600 gaaatcgatg ggaatcgtta ttaaaatcgg ttaggggaac ttctgacaac acggcagagg 30660 tgaattttga tgctgacatt aatgcactat ttatcccata atgattttaa tgcagtcgac 30720 ctacctattg atcatattta cttaaataca atttgacttt aatagtttta tattactttg 30780 ttaacataac ttatctttct aggtatttta taatttcaag gatttatgta tagtacgaat 30840 ttactgaaat ttttgcacat aagctttgta ttaaattttc taaagccgta cttctgtaat 30900 tactacataa aatattacaa tgcacagatt tttatttaca aacaagcggt tgtcgtagca 30960 accactttgt ttaccctcaa aagttaccac ctgcgttttg ttagaaacaa ataccaaatg 31020 gcgagtgttg caattaaaga gcccaaaact gctataaccc cgaagaagaa gtccaaagcc 31080 tctcgtcttt gctttactcc gccaactaat cttcataata ataaaaaaaa tatattctac 31140 actcgctacg attgcattgg tgaaggcggc tttgcgagat gttttcgagt caaagataat 31200 tatggaaata tttacgctgc taaagttatt gctaaaaggt cactacaaaa tgataaaaca 31260 aagctgaagc tctttggaga aataaaggtg caccaatcca tgagtcatcc aaacatcgta 31320 ggatttatag attgttttga agattcgacg aatatttact taattttgga gctttgtgaa 31380 cataaatctt taatggaact tttacgtaag cgaaaacaat taactgagcc agaggttcgg 31440 tatttaatga tgcaaatttt gggagctttg aaatatatgc ataaaaagag agtcattcat 31500 agagatttaa agcttggaaa tattatgctt gatgagagta acaatgtaaa aattggtgat 31560 tttgggcttg ccgcgctttt aatggatgac gaagaacgta aaatgactat ctgtggtaca 31620 ccgaactaca tcgcacctga aattttgttc aattcaaaag aaggacattc atttgaagtt 31680 gatctttgga gtgctggagt agtcatgtat gccctcttga ttggaaagcc acccttccag 31740 gataaagagg taaagacaat ttataggaag ataaaagcca actcatatag ttttccttca 31800 aatgtcgaca tatctgcaga agcaaaagat ttaatttctt ctcttctgac acatgatcca 31860 agcattcgtc ccagtattga cgatattgtt gaccatgaat tctttcacac tggctatatg 31920 gcttctacac ttccagatga aattttacat tcaatgccta tatggccttc ttcccaatca 31980 aaatcaagct ttcagagaaa cctggacttc gttgcctctg cttccggagt aggctttgga 32040 aattcagcag gtgtagaaaa gaataaacct tatgcacttc gaacagatga agttgataat 32100 gatcgaatat taccaagtgt tttaagtcca agggaccgtg tcaaccctgt tatgaaaata 32160 ggaccggaaa ccaaacctgt accatcaaag ctctctacag ccctccatgc agctcgtaaa 32220 tccactgatg gaagtttagg ctcaagagtt aaagttttga gagaagaatc acaatcattt 32280 gttccaacta agagcgctgt cactgaacaa gttgaaccta ttcaattaat tcggtcttta 32340 tctgcaaata cagtttcaag actttctaag gttggaaata tgaaatcaga catttggatc 32400 agcgtaaaga agacagctct taaaatcggg atggcattgg aagcacatac acacgcttta 32460 acttcagagg atgctgactc tgagcccgtt ctttttatta caaagtgggt tgattattcc 32520 aacaaatatg gtttaggata ccagctatcc gatgaatcgg ttggcgtaca ctttaatgat 32580 gatacatcct tgcttttttc agctgatgag gaggttgtcg agtatgcttt acatcctaaa 32640 gatacagaaa ttaagccata tatttatcct gcttccaaag ttcctgaatc tataagaagt 32700 aaacttcagc ttttaaagca ctttaaaagc tatatgggac aaaatctttc gaaggctgtg 32760 caggatgaga gttttgaaaa acccaaaaac tcaacttcca ataccatgct tttcatgcag 32820 cattatcttc gtacgcgtca agctataatg tttagattaa gtaacggaat ttttcagttc 32880 aatttcctgg atcatcgaaa agttgttatt tcctctaccg cacggaagat cattgtatta 32940 gataaagagc gagagagagt ggaattgcct ttgcaagaag catccgcatt ttcagaagac 33000 ttgagatctc gcttaaagta tattcgcgag acgttggaat cgtgggcgtc gaaaatggaa 33060 gtgagttaat aataccgtta atctatactt gggcgttaag ttactatgct gtctattttt 33120 ccatatttca catcctcatt tttgtactat tcatccattc aattcagttt tatgttaatg 33180 ttttactaat tcttttttta ttatttcttt ccctcagata catcttttaa acgcaggagc 33240 tcttgacgaa taagttataa acttaaatta tagctgcaaa tatcagctta atcccttttc 33300 aaaatttttt attttttgct tttaaattga tcgctgcaaa ttctgtctta aggcgacact 33360 tatttatcta atcaaaagga ttcacaaatc tcaatgttcc aagtgttatc caaaatgtta 33420 gactagtcac agctatgtta attgattttt attctctcgc tgtaactgaa atccttttca 33480 cagattagat acatgttttg ctaattatgt cagtaaaatg tgtacagttg agttcaatct 33540 gctgcatatt aagaatcaca gactttgtaa caccaaatta aattaattaa tagtagcatt 33600 atttattgtt tacaaggcat taatttatac ttcactaagt atatcaaaag agcaatagta 33660 ctggttttta ctagcaactg tcacgttgaa tccaaatagc aggaacattt ttataataaa 33720 taggctgatg cgataaaaga actgtttgct tttaaagtac ttataaacta attccagcaa 33780 tacataatta gtaaataaaa tgctttctct acctacgcta tgctatgtta atagcgattg 33840 aggaaattac ctaacggaca atacactaat tagtttaacg aatatgaagc tttgcgtagc 33900 atgcgttaaa tctctttact atttcataaa caagccgagt caaattgatg aagtatccaa 33960 gaacgcatat ccaattcccc agtatgcttc ggaatcgttt gtttaaaacc ccacatcaga 34020 ctggtaagga tattaatgct ttttcaaatt gctcttcaat ttgtactaac gttttgtagg 34080 ctttcaatgg aggttaggcg ctccggcgac gggaattaca atcaggaacc aacctattag 34140 aagctattca ggtctgcgag gaaatttttt gattgataaa agactctctc ctgtcaaatt 34200 taataaatat agtccatcag atatagtatt ctataatatc ggctcttcaa gactttactc 34260 tacagaaact cctactcctt ctaaagttaa ggaagccccg aaacaggttg ctgcggaaga 34320 gactaagcca actactgtgg ttaaaaaacc gtcaatatgg caaagggtta aaggcggtgt 34380 attacatttc tgggatggta ctaaacttct tggtgtcgag attaagattt cttcaaaact 34440 ggtttataag atggctgtcg gttacgaact tactcgtcgt gaaagtcgtc aacttaccag 34500 aactttaaag gatattggaa gacttgttcc attctcagtg tttgttgttg tgccgtttgc 34560 cgaattattg ttgcccattg cagtcaagct gtttcccaat ttgcttccta gtacatttga 34620 agatgcaaag gataaggagg ctaagaaagc acaacttcga aagactagaa atgaagtatc 34680 caacatgcta cgaagcacct taaaatcggg aaaatttact ttctccaacg agactcgtga 34740 atctaaagag ttcagagatt tttttcaaaa ggtgcgtact agtggtcaat ccccatctag 34800 agaagaatta attgaggttt gcaaatactt taaggatgac ataactcttg ataacttgtc 34860 gcgtgcacaa ttagtagcta tgtgtcgcta catgaatcta aatgcattcg gaactgatcc 34920 tctattgcgt tataatatcc gtcatcgaat gcgtcaaatt cgtcgtgacg atcgtgctat 34980 ttacattgaa ggaatcaact cactttcaat tcccgagctt ttcaatgcct gtaattctcg 35040 tggtattcgg actcagggcc tctctcctgc taagttgaaa gaagaattaa gtgtctggct 35100 tgatatgcgt atcaaacatg gaattccttc tgttattttg atgctttcaa acgcattctc 35160 ttatggatat aacgagggta cttatgattc acgctgggat gcactgcaag atactcttgc 35220 ttctatccct gacgagcttt atcatgagac tgttgttgat atgccaacaa aacaagtatc 35280 aaacaaggaa aggctcgaaa ttttacgcga gcaagaggag cttattgagg aagaagctga 35340 acacgtcgcg gaacatccag atttggctaa gaaacaaacg gaagaaaaca aagctacttc 35400 caagcctgca gtctctgcga agtcaccgga atctaacatt ccaaagaatg aaagaaaata 35460 atttctgtga ttttccaatc aactcttgtt ttgcaacttt tccttttaga attttgttta 35520 attatgtctc acaatccgtc atatctgttt atttttcaat ccatttaact tatttctacc 35580 attctttttt aagtttttcc tttacgcttt taggttagaa cttgaacgcc tgcatcctag 35640 gactgctttt attctagact acctcttttt tgtggtgcgt atttgttttt gccgctaaat 35700 atcaaaatca tagctgccat aacaaatatc ttaaaagttt gatttttgtt tacgagaatg 35760 atatgaaaaa ttcaaacaat atttttggct taattcgttt tgtttctttt tttctcaata 35820 catttcacca acattgcatg gttattagta aatttcgaaa taaatatata tagctttgtt 35880 tcagtattta tttaaagaga tttaaagaaa agaaagaaag aaatcctttt atgatatgaa 35940 tagtttttta tttttatttg ttttatttca tggaagtcgg tttagaggta ttaggaagca 36000 atgtaagcac ttcttccgct gccagtagga cattttttgg aatacctgta gcgtcagttt 36060 agttgtattg caaacaaaaa cttacctgcc atttcagcga ctttgagccc gtgtgattga 36120 tagttaacgc ctttttttag tttgtaatcg aaactgaaag tgtgatcatc ctgtgtatcg 36180 agttaaaaaa aatttcatct aaaacttaat cttactctgt caatgcttaa attagtgcaa 36240 taacactcta catttttaaa agatttcgtc aagttagtaa gttgatgagc gtgggttgca 36300 aatagagttc tagaatggtt aattgtagaa agatatttta gacaaccgta agcaattgca 36360 ataccatcgc ttgctgtggt gccacgtcca atttcatcca tgattacgaa agaccttctt 36420 gtagcatttt ttaaaataaa agaagtctcc atcatttcaa ccatgaaagt agatttttgc 36480 tgatacaaat tatccgcaga tcctattctg ctaaaaattt ggtcaacaat ccctattctg 36540 gcattactag ctggaacaaa gcttccaatt tgcgctagaa tagaaataat tgcgttttgt 36600 ctcaaaaatg tactttttcc ggccatgttt ggcccagtaa tcaaccaaat attaacgttc 36660 ccatttccaa caaaacagtc atttggagta aagggaataa gtttatgact caatcccttt 36720 tccacaatcg gatgtcgtcc ctgtattaca gtatgagcat gtgaatcatc aaccactgga 36780 cggacaaaat cctgttcctg tgctaaagtc gctaaagaag tagaaatatc taattcatcc 36840 agggcattag ctaatgaacg caatgttttg tgatggctaa ctatctcatc agtgatactt 36900 ttcaagactc tctgctcctc ttgatgtata tgcaatttag tattctcaag atccattcca 36960 agcgaagtcc agcccggtag ttgaaagctt gccgtactct ttgttgattg aaagagaact 37020 gcttgagtaa attttttgat aaatcgctca atggtttcgt tgcctgacaa ttttaaatgt 37080 acataataaa gctttgcagg actttttcgt aaagtggctt tcttccctaa gcgtttactc 37140 aaatcctctt gaagtttatc gtaagaagca aacaaacttt gaagcttctc atgcagtttt 37200 cgaagattat tattaaaatt ggatttgaca acccaatttt ccttgaaact ttgtctaata 37260 tcaaattcag aagatagtga tttctttaca atctctactt gagcattttc atcttgaagt 37320 atttcttcag cttcttgagc aattacttcg gtttcttctt cttcgtttat tttctgcttc 37380 atcaaagcat tttcatccac ggcattattt attagttgtt tcagctcatc atgcggatgc 37440 atatttaata aaagtaacct aaaagcagat gaagattcaa ggggagatag taaagaatga 37500 atttccttag taatagagaa attatcagcc atttttaata aatcataaga gttaccccta 37560 cccatcaata aatgttgaag aatccgatgc gtatcattcg atttcttcaa caagtttatt 37620 accttcgaac acaactccgg aagcaactta aatttttcaa ctaagtccaa cctattgttt 37680 atttcaacaa tgttagtaga aggtgcacaa agtctccggg ttaataggcg ggatccagat 37740 ttagtaaccg ttttattaat ggcatgaaga agggaacccg tgtagcggtt ctggtataag 37800 gatgatctga tttcaagacc tttcattgct gactctccaa taatcatgta ttcgtttaac 37860 gaaactcgaa tgggtggttg aatatttgga tgcgaatttt gaagccgatc agcgatatat 37920 gatattaatg tacagccagc tgtaacctcc aattttgtac aatattttat aaaggaaggg 37980 tcaatttcct tttctaaaaa cttattccaa caatccagag attggtatcg attttcgacg 38040 taggatagga aatactttct ttcttgaata aaggaataaa taggatgagt agtaaaactt 38100 ttcaaacttt cgtctaaaac aatttctcta ggagaaattc tagtcaaatc ccctgctaaa 38160 cgctgcaagt tggaatcttg tgtgaagaac tcaccagttg acaagtcgag ccatgataat 38220 ccaattttac aatcagcgaa acaatcctta tcttcagcag ttccttgatt agaaatatcg 38280 gaactaaaaa aattgggatc gaagacgaca gttaggatat agttgctttc ataaggattc 38340 ataaaatttt cgtcaattag agttcctgga gttatgactc gggtgacaga t 38391 //