ID   SPAC22A12  standard; DNA; FUN; 32814 BP.
XX
AC   Z99295;
XX
SV   Z99295.1
XX
DT   18-SEP-1997 (Rel. 52, Created)
DT   04-OCT-2001 (Rel. 69, Last updated, Version 5)
XX
DE   S.pombe chromosome I cosmid c22A12.
XX
KW   40s ribosomal protein s15a; aminoalcoholphosphotransferase;
KW   atp citrate lyase; bip; dihydrofolate reductase; dihydroxyacetone kinase;
KW   dolichyl-phosphate-mannose--protein mannosyl transferase;
KW   endoplasmic reticulum; glucose regulated protein;
KW   heat shock protein 70 family; Homol D box; oxidoreducatase;
KW   phosphatidyl synthase; pre-mrna splicing factor; rps15a-2;
KW   short chain dehydrogenase; sorbitol utilization;
KW   transcription elongation factor.
XX
OS   Schizosaccharomyces pombe (fission yeast)
OC   Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes;
OC   Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces.
XX
RN   [1]
RP   1-32814
RA   Pearson D., Churcher C.M., Barrell B.G., Rajandream M.A., Wood V.;
RT   ;
RL   Submitted (10-SEP-1997) to the EMBL/GenBank/DDBJ databases.
RL   Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre,
RL   Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail:
RL   barrell@sanger.ac.uk
XX
DR   GOA; O13896; O13896.
DR   GOA; O13898; O13898.
DR   GOA; O13899; O13899.
DR   GOA; O13900; O13900.
DR   GOA; O13901; O13901.
DR   GOA; O13902; O13902.
DR   GOA; O13903; O13903.
DR   GOA; O13907; O13907.
DR   GOA; O13908; O13908.
DR   GOA; O14469; O14469.
DR   GOA; P36604; P36604.
DR   SPTREMBL; O13894; O13894.
DR   SPTREMBL; O13895; O13895.
DR   SPTREMBL; O13897; O13897.
DR   SPTREMBL; O13899; O13899.
DR   SPTREMBL; O13900; O13900.
DR   SPTREMBL; O13901; O13901.
DR   SPTREMBL; O13903; O13903.
DR   SPTREMBL; O13904; O13904.
DR   SPTREMBL; O13905; O13905.
DR   SPTREMBL; O13907; O13907.
DR   SPTREMBL; O13908; O13908.
DR   SWISS-PROT; O13896; RPCZ_SCHPO.
DR   SWISS-PROT; O13898; PMTX_SCHPO.
DR   SWISS-PROT; O13902; DAK1_SCHPO.
DR   SWISS-PROT; O14469; RS22_SCHPO.
DR   SWISS-PROT; P36604; GR78_SCHPO.
DR   SWISS-PROT; Q10264; YF31_SCHPO.
XX
CC   Notes:
CC   Details of yeast sequencing at the Sanger Centre are available on
CC   the World Wide Web.
CC   (URL, http://www.sanger.ac.uk/Projects/S_pombe/)
CC   Protein coding regions (CDS) have been predicted with the help
CC   of computer analysis using the Genefinder program in PomBase
CC   (an ACEDB database) with additional predictions for the
CC   branch-acceptor sites supplied by the program Sp3splice.
CC   CAUTION: It is possible that for any individual CDS we may have
CC   underestimated or overestimated the number of introns/exons or
CC   we may not have chosen the correct splice donor/acceptor sites.
CC   CDS are numbered using the following system eg SPAC5H10.01c.
CC   SP (S. pombe), A (chromosome 1), c5H10 (cosmid name),
CC   .01 (first CDS), c (complementary strand).
CC   The more significant matches with motifs in the PROSITE
CC   database are also included but some of these may be fortuitous.
CC   The length in codons is given for each CDS.
CC   IMPORTANT: This sequence MAY NOT be the entire insert of
CC   the sequenced clone.  It may be shorter because we only
CC   sequence overlapping sections once, or longer, because we
CC   arrange for a small overlap between neighbouring submissions.
CC   Cosmid c22A12 is overlapped at the 5' end by cosmid SPAC56F8,
CC   EM:Z69728 and at the 3' end by cosmid SPAC4C5, EM:Z98560.
XX
FH   Key             Location/Qualifiers
FH
FT   source          1..32814
FT                   /chromosome="I"
FT                   /db_xref="taxon:4896"
FT                   /organism="Schizosaccharomyces pombe"
FT                   /strain="972h-"
FT                   /clone="cosmid c22A12"
FT                   /map="IL"
FT   misc_feature    1..218
FT                   /note="nominal overlap with cosmid SPAC56F8, EM:Z69728 S.
FT                   pombe chromosome 1"
FT   CDS             complement(1..317)
FT                   /db_xref="SWISS-PROT:Q10264"
FT                   /note="SPAC22A12.01c,"
FT                   /partial
FT                   /gene="SPAC22A12.01c"
FT                   /gene="SPAC56F8.17c"
FT                   /product="DNA repair protein for interstrand crosslinks; by
FT                   similarity to yeast pos2"
FT                   /protein_id="CAB16571.2"
FT                   /translation="MSKRKSSSILDFFKKSNNGKNMWGNEAVSVEKTDSTTKPSTVKNA
FT                   ISSSQIKNEKFSQEVLLQFNDPSFTSEVGESPQWQSFGDANILEPLKNELVKNEESTMS
FT                   E"
FT   CDS             complement(1151..1525)
FT                   /db_xref="SPTREMBL:O13894"
FT                   /note="SPAC22A12.02c, len:124aa"
FT                   /gene="SPAC22A12.02c"
FT                   /product="hypothetical protein; sequence orphan; has
FT                   transcript on microarray"
FT                   /protein_id="CAB16572.1"
FT                   /translation="MEQFEIIRESDADPYYFNKNLRLEECEIDGFTSIYKAPPPYSFVA
FT                   GLSKNTSSNSFVIHKCLPPLQRNNTIRKRKRNPFLADRPYCINSEDMPLSDDRDMLKER
FT                   HVKSRKLLLKEKGNRFYRRS"
FT   CDS             complement(1744..2877)
FT                   /db_xref="SPTREMBL:O13895"
FT                   /label=csn4
FT                   /note="SPAC22A12.03c, len:377aa; similarity: some to C. int
FT                   estinalis, P91586, COS41.8, (409aa), fasta scores, opt:240,
FT                   E():1.6e-05, (23.3% identity in 258 aa overlap)"
FT                   /gene="SPAC22A12.03c"
FT                   /gene="csn4"
FT                   /product="COP9/signalosome complex subunit 4; PCI domain"
FT                   /protein_id="CAB16573.1"
FT                   /translation="MEEVVHYFLEGNMPVAQFREALALHYTNEKELFEQAKRCLNICCG
FT                   SNNFAKRNDVLFSLLDVAVSISSLELRKELISELYVPVQSLEEAPSEYLVSCCLQLATI
FT                   YEAEQNFELLCSSLEAVEKHGHFENDLEQLLLLRIRLGDAYLKLGKAEKAILTVRTSIP
FT                   LAFKVSNDQLLMELQLCNARALDETGQFLEAAKCYYRVLQYKVPGNELIYRENLCSVAQ
FT                   CLLLAIPSPIVLQFLQEISLQPSVREIPFYSLVEKYLKRKFIGKEDGAFLLPFLLPHQV
FT                   IHMNRLIEDGRHFLETNILFLSEFFEVSSTSILAKHFKLSEEQVDTVVADMVIQERLNA
FT                   SIDQCEGYITFLPEYGKANNLPNYVNKIATVLQHYGS"
FT   misc_feature    complement(1795..2031)
FT                   /note="Match to PF01399 PCI, PCI domain Score 88.36"
FT   CDS             complement(3769..4161)
FT                   /db_xref="GOA:O14469"
FT                   /db_xref="SWISS-PROT:O14469"
FT                   /note="SPAC22A12.04c, len:130aa"
FT                   /gene="SPAC22A12.04c"
FT                   /gene="rps15a-1"
FT                   /gene="rps22-1"
FT                   /product="40s ribosomal protein S15A/S22A"
FT                   /protein_id="CAB16574.1"
FT                   /translation="MVRQSVLADCLNNIVNAERRGRRQVLIRPSSKVIVKFLTVMQKHG
FT                   YIDEFTEIDDHRSGKIVIQLNGRINKCGVISPRFNVKLKDIEKWVNQLLPSRQVGVIVL
FT                   TTSRGIMSHNEARAKDAGGKILGFFY"
FT   misc_feature    complement(3772..4149)
FT                   /note="Pfam match to entry PF00410 S8, Ribosomal protein
FT                   S8"
FT   misc_feature    complement(3811..3864)
FT                   /note="PS00053 Ribosomal protein S8 signature"
FT   promoter        complement(4232..4239)
FT                   /note="Homol D box"
FT   CDS             4648..4977
FT                   /db_xref="GOA:O13896"
FT                   /db_xref="SWISS-PROT:O13896"
FT                   /label=rpc11
FT                   /note="SPAC22A12.05, len:109"
FT                   /gene="SPAC22A12.05"
FT                   /gene="rpc11"
FT                   /product="dna-directed rna polymerase iii 12.5 kd
FT                   polypeptide"
FT                   /protein_id="CAB16575.1"
FT                   /translation="MQFCPTCGNHLIVAVDEEGRNAFDCRTCPYHFPISTFLYSRHEFA
FT                   QKEVDDVLGGEEAFESNQQTEVTCENTKCDNNRAYFFQLQIRSADEPMSTFYRCTKCKF
FT                   QWREN"
FT   CDS             complement(5461..6750)
FT                   /db_xref="SPTREMBL:O13897"
FT                   /note="SPAC22A12.06c, len:429, Low
FT                   SIMILARITY:Schizosaccharomyces pombe, DYR_SCHPO,
FT                   dihydrofolate reductase, (461 aa), fasta scores: opt: 438,
FT                   E():3.6e-22, (23.3% identity in 455 aa)"
FT                   /gene="SPAC22A12.06c"
FT                   /product="similar to S. pombe dihydrofolate reductase
FT                   Dfr1p"
FT                   /protein_id="CAB16576.1"
FT                   /translation="MKSATKSKILCIHGYAESGELFSVKLRALRERMADSVDFYFPTGP
FT                   IELDKAKDELNGSGFDALSTVFSSSPASHRRGWWRINEYADTKQLEPTKAFEYLASYIK
FT                   EHGPFDGILGFSQGTNLAANLAALVTIPKYQEYFSQPPFRFALFFSGYFRPLLMDGAVH
FT                   ATKLDLPTLHLLGKYDTVLSTETSTTLVRACKDAQVLFHPAAHQIPAPHAYVEPAADFI
FT                   DFFSREDWPIISKHISLIVPTKKVNTTSAQTSLNNVEHDLISKIMSRSFKGGINVVVSD
FT                   LQMFNEYKRIFGPKVLSLVVTDGQEPDTYSENVHYTPNFKGALAYLEAYQNSIGRIYVI
FT                   GDKKLLTLGMLCRCTKRIIAITDAEDKFISQSSAQQVSGSLPFLEHSKEWLKAKSSQIR
FT                   QWTGQSRLKHMSQDNSGEPVTMKLQMWERL"
FT   CDS             complement(8347..11028)
FT                   /db_xref="GOA:O13898"
FT                   /db_xref="SWISS-PROT:O13898"
FT                   /note="SPAC22A12.07c, len:893aa, similarity: to YDL095W, PM
FT                   T1_YEAST, P33775, dolichyl-phosphate-mannose--protein manno
FT                   syltransferase 1, (817aa), fasta scores, opt:1505, E():0, (
FT                   33.2% identity in 747 aa overlap)"
FT                   /note="SPAC22A12.07c, len:893, SIMILARITY:Candida albicans,
FT                   PMT1_CANAL, dolichyl-phosphate-mannose--protein
FT                   mannosyltransferase 1(ec 2.4.1.109)., (877 aa), fasta
FT                   scores: opt: 1558, E():0, (33.9% identity in 832 aa)"
FT                   /gene="SPAC22A12.07c"
FT                   /product="dolichyl-phosphate-mannose--protein
FT                   mannosyltransferase 1(ec 2.4.1.109)."
FT                   /protein_id="CAB16577.1"
FT                   /translation="MDKQSTFQDPKEKHRIQRDVKLSRPRKRFSFLDYVVVIFLTVVAF
FT                   CVRAQRLMNPAKVVFEELRYYNYAVDYVNNKLLMDVYPPLGKLLFSLVAALTGNKYELN
FT                   TLDEPGQQYPFTDVAYSMRLFTCLLGSLLVPLMYGTVYFPTKSKTAASLAALFVIFDNG
FT                   LITMSRYIMIEIPALYFMSLTAFYWSVYEAQQKRPFSLRWHTSLLSTGVALGLALSTKL
FT                   SAMFTFGWLLILAAFHLWNLLGDLSVPMYRIVKHLFSYIFYLIGVPITVYLAVFAVHSH
FT                   IAYKASVADAFLPPEHRHALAGNRFDDQFADVAYGSLVTIRNAIPEHGYLHSSELLYPE
FT                   GTEQQIISLVDEPNQNALWIIEHEHSQDNNRSNIELLKDGSVVRLRHVMTGRALHSHEH
FT                   KPIVSNNDWQLEASAYGGFGFEGDANDLFRIQILEKKSKHATSNGTVETLNTKFRLIHV
FT                   FANCELMSSHRRFPDWGDYQREVTCCRNCVERSTTWFIESNYHDGLPSDSRKITYRKPG
FT                   FLESFVEHNKLMWLKDRKMGDGHVYESSALTWPLLLGPLRFFYEQHLQVFFMGNPFVWY
FT                   SVISLVAFFVIVQIFCLARWNLGYNDFGPSAFHYNYNIGKFVVAWLLHWAPYILETDRV
FT                   FLYHYLPALYFGIAALGVSWSFLGNAVFGNRTAYKALSVIIMALMFLVYRLYSPFTYMT
FT                   TLTKSSCRALELKGSWNFHCNTYLDNLSDYKFSSDAGETYFEKAAPHPFVYSEDTAKKS
FT                   EGDTPLNKNLNDYYPSWDQRVEAGYKLAAQQKAEQEAREAAEKAASEAAERSSSEAAAS
FT                   SSSESVAAASVEAERLAMEADEFNGASETVDGASVEAERSAMEAAALNNAAESTEVVGS
FT                   SPESVASEQEENVAESAQARVE"
FT   CDS             join(complement(13524..13651),complement(13425..13481),
FT                   complement(12887..13381),complement(12029..12795),
FT                   complement(11721..11986))
FT                   /db_xref="GOA:O13899"
FT                   /db_xref="SPTREMBL:O13899"
FT                   /note="SPAC22A12.08c, len:570, SIMILARITY to N-term of
FT                   :Saccharomyces cerevisiae, YK50_YEAST, hypothetical 39.4 kd
FT                   protein in met1-sis2 intergenic region., (352 aa), fasta
FT                   scores: opt: 627, E():0, (37.4% identity in 358 aa)"
FT                   /gene="SPAC22A12.08c"
FT                   /product="CDP-alcohol phosphatidyltransferase"
FT                   /protein_id="CAB16578.1"
FT                   /translation="MLHTINYRSWHLAARQLGRSTFRKFTTESSTKSPIADVCFAFDSI
FT                   DGVLIRGGRGLKEGTKTLKFLQKNNIPFILLTNGGGMHESVRAQRLSKTLSVSLTEDDF
FT                   CQSHTPFRALADKYKHVLVLGGKDNSVRETAEKYGFKSVINELDVIAKLGTPFWPFTSF
FT                   NEEDIKDAKDFDVTRPIEAVFTYVDPVRLGLDLQLVMELGQSKNGVLGTVSKTANEGPD
FT                   IYFSNADLIWPNEYPLPRLGQGAFAICCESVFKELTGKDLRNTKYGKPHKLTYDYAKNI
FT                   LMKKHKTLGITNPPKEIFMVGDNPESDIRGANNYGWTSILVRTGIFQGDNSPKYSAKHV
FT                   SDNVWEGVRWALSKHVPAAKLNKSMGEVRGFHTSSRVLNTVTKSNNSKPIQRPLRENIF
FT                   TLPNLLTFSRLLSAPLIAYLYIYDYTKAAACFFLYAGFTDLVDGYIARKFDLGSIAGTV
FT                   LDPLADKTLMTCLTICLAVRETMPLTLASLIIGRDVLLVSAVSYLRYKSLPAPKTFRRF
FT                   FDFAIPTTELKPTRISKVCRNGLLSTDLCKQLVEYSFTTAVTRTFDYRAHTSF"
FT   misc_feature    join(complement(12029..12191),complement(11733..11986))
FT                   /note="Match to PF01066 CDP-OH_P_transf, CDP-alcohol
FT                   phosphatidyltransferase Score 138.96"
FT   misc_feature    complement(11987..12000)
FT                   /note="ctaaccttatctag, splice branch and acceptor"
FT   misc_feature    complement(12023..12028)
FT                   /note="gtatgc, splice donor sequence"
FT   misc_feature    complement(12796..12811)
FT                   /note="ctaacagcttttatag, splice branch and acceptor"
FT   misc_feature    complement(12881..12886)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(13382..13393)
FT                   /note="ctaacttgtaag, splice branch and acceptor"
FT   misc_feature    complement(13419..13424)
FT                   /note="gtaagc, splice donor sequence"
FT   misc_feature    complement(13482..13491)
FT                   /note="ctaaccaaag, splice branch and acceptor"
FT   misc_feature    complement(13518..13523)
FT                   /note="gtaata, splice donor sequence"
FT   CDS             join(complement(15554..15680),complement(15198..15504),
FT                   complement(14818..15134),complement(14358..14732),
FT                   complement(13995..14314))
FT                   /db_xref="GOA:O13900"
FT                   /db_xref="SPTREMBL:O13900"
FT                   /label=sap114
FT                   /note="SPAC22A12.09c, len:481, SIMILARITY:Caenorhabditis
FT                   elegans., Q10577, pre-mrna splicing factor prp21., (655
FT                   aa), fasta scores: opt: 636, E():7.5e-28, (30.9% identity
FT                   in 482 aa)"
FT                   /gene="SPAC22A12.09c"
FT                   /product="pre-mrna splicing factor"
FT                   /gene="sap114"
FT                   /protein_id="CAB16579.1"
FT                   /translation="MSSLMEFQDRNTTNNETEHQKSITDQSSSVPAGVILPPPAIREII
FT                   DKSASYVARNGPAFEEKIRQNEQANTKFAFLHANDPYHPYYQHKLTEAREGKLKSHATG
FT                   LSTQKTSTLARPIQKPIEATIPAPSPYLFSEPLPSISSLDLDVLRLTARYAAVRGSSFL
FT                   VSLSQKEWNNTQFDFLKPNNALYPYFMRIVQQYTSLIREPISSPEQELRENVRDPYSLL
FT                   SKIQPRVRWQSHMESQKKKQKEEAEKEKLEYAQIDWNDFVVVEVIQFTKSDEHAKLAKP
FT                   TNLADLQTATLEQKSAMFTMPDQNYTIEEAPPTAEPWEPISAPKKQEFGVSLPPSLASP
FT                   EKGGISSTTSVSPAAQASPVLSTTTQPKVQKPVPKAFQPKVPMEISPFSGELVPATELE
FT                   EHMRLKLLDPRWQEQRKVEESRKSTLNLENVNVAANMKRLVSQRTDLFDVQNGVEISQE
FT                   EIERRKRAATQSAWGATPTNKRR"
FT   misc_feature    complement(14315..14328)
FT                   /note="ctgaccctgtttag, splice branch and acceptor"
FT   misc_feature    complement(14352..14357)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(14733..14746)
FT                   /note="ctaacttgtcttag, splice branch and acceptor"
FT   misc_feature    complement(14812..14817)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(15135..15154)
FT                   /note="ctaattaaccgtgaatctag, splice branch and acceptor"
FT   misc_feature    complement(15192..15197)
FT                   /note="gtaagt, splice donor sequence"
FT   misc_feature    complement(15505..15518)
FT                   /note="ctaacgtagcttag, splice branch and acceptor"
FT   misc_feature    complement(15548..15553)
FT                   /note="gtgagt, splice donor sequence"
FT   CDS             join(16096..16232,16283..17306)
FT                   /db_xref="GOA:O13901"
FT                   /db_xref="SPTREMBL:O13901"
FT                   /note="SPAC22A12.10, len:386aa; similarity: to YHR123W, EPT
FT                   1_YEAST, P22140, ethanolaminephosphotransferase, (391aa), f
FT                   asta scores, opt:757, E():0, (35.8% identity in 386 aa over
FT                   lap)"
FT                   /note="SPAC22A12.10, len:386, SIMILARITY:Saccharomyces
FT                   cerevisiae, EPT1_YEAST, ethanolaminephosphotransferase,
FT                   (391 aa), fasta scores: opt: 757, E():0, (35.8% identity in
FT                   386 aa)"
FT                   /gene="SPAC22A12.10"
FT                   /product="aminoalcoholphosphotransferase"
FT                   /protein_id="CAB16580.1"
FT                   /translation="MQLNRKQLKNLHNYKYSAIDNSLLSKYILKPYWWNQLLKVIPMSM
FT                   APNLITLIGLGFVVINILTMLVYKYHYEMDAFPSWVYASWAIGLFLYQSFDAIDGSQAR
FT                   RTGTSSPLGQLFDHGVDAINTSFEVLLTIELLQLDMFSSILTQFASLLYFYISTWEEYH
FT                   TGTLYLSYFSGPVEGIVMVIGLFALTAIKGDSFWLKLHPTPESWGFVRSFLPYYTYGSC
FT                   LYNFMAFALLLNVLQSLRNALQAVQKNNGSVIKALSGILPYFLQWMAVFSLYAKYPAFF
FT                   EHHFLTIFCLNAFIFAYSVGVVIVSHITESPFPYWNVLILPFLVDAVDAYTFGVLKNVQ
FT                   TEYFFCYVGICIGVYGNFVAHVIAMITEEYGIKCLTIPSKPESKKN"
FT   misc_feature    16233..16238
FT                   /note="gtatga, splice donor sequence"
FT   misc_feature    16267..16282
FT                   /note="ctaactctttacttag, splice branch and acceptor"
FT   misc_feature    16440..16508
FT                   /note="PS00379 CDP-alcohol phosphatidyltransferases signatu
FT                   re"
FT   CDS             18590..20332
FT                   /db_xref="GOA:O13902"
FT                   /db_xref="SWISS-PROT:O13902"
FT                   /label=dak1
FT                   /note="SPAC22A12.11, len:580"
FT                   /gene="SPAC22A12.11"
FT                   /gene="dak1"
FT                   /product="dihydroxyacetone kinase; isoenzyme I; subcellular
FT                   localization of GFP fusion; Cytoplasmic dots and lines"
FT                   /protein_id="CAB16581.1"
FT                   /translation="MDKHFINDPEVLVLDGLKSLADMNKTLTVHEEGKFIYFHDYNKKN
FT                   VSVISGGGAGHEPTHSSFVGKGMLTAAVSGSIFASPSSKQIYTGIKQVESEAGTLVICK
FT                   NYTGDILHFGMALEKQRTAGKKAELIAVADDVSVGRKKSGKVGRRGLSGTVLVHKIAGA
FT                   AAARGLPLEAVTTIAKAAIDNLVSIGASLAHVHVPGHEPIAKEDEMKHDEMELGMGIHN
FT                   EPGCKRISPIPSIDDLIAQMLKQMLDQSDKDRAYVKIEGDDEVVLLMNNLGGLSMLEFS
FT                   AISHKVKEALAKEYKINPVRIFAGPFTTSLNGLGFGITLLRTTDRVKVEGEEYSLVDLI
FT                   DQPVEAIGWPLCQPSDLKSKNKIGNVSIEEGQKDVKSPVTVDKEKVRQAIVNSMENLIK
FT                   AEPKITKFDTMAGDGDCGTTLKRGAEGVLKFVKSDKFSDDPIRIVRDIADVIEDNMDGT
FT                   SGALYAIFFHGFAKGMKDTLEKSKDISSKTWAAGLKVALDTLFKYTPARPGDSTMCDAL
FT                   VPFVETFVKTNDLNAAVEEARKGADATADMQAKLGRAVYVGDDVKVPDAGALGVVAIVE
FT                   GFTK"
FT   CDS             complement(20734..21456)
FT                   /db_xref="GOA:O13903"
FT                   /db_xref="SPTREMBL:O13903"
FT                   /note="SPAC22A12.12c, len:240, SIMILARITY:Saccharomyces
FT                   cerevisiae, Q08285, chromosome xv reading frame orf
FT                   yol142w, (240 aa), fasta scores: opt: 517, E():4.4e-28,
FT                   (36.9% identity in 236 aa)"
FT                   /gene="SPAC22A12.12c"
FT                   /product="putative exosome 3'-5' exonuclease complex; rRNA
FT                   processing; by similarity to yeast RRP40"
FT                   /protein_id="CAB16582.1"
FT                   /translation="MAEVEEKGLLSYYFPGERIPDSIISQDGSIRLGPGLVFQKKDREE
FT                   EIVVSKAGRLHQTGKNAMLIDSRTKRYIPATNDQVIGQIISRFAEGYRVDIGSAHIAQL
FT                   NALAFENVTRKSRPNLNVGSLVYARVSLADRDMEPELECFDATTGKAAGYGELKNGYMI
FT                   TGLSLSHCRKLILPKNTLLQTLGSYIPFEIAVGMNGRVWVNSENLSTTVLICTAIRNCE
FT                   FMSDEEQIKYCKDLIKKL"
FT   CDS             22004..22366
FT                   /db_xref="SPTREMBL:O13904"
FT                   /note="SPAC22A12.13, len:157aa"
FT                   /gene="SPAC22A12.13"
FT                   /product="human downs syndrome critical region-like"
FT                   /protein_id="CAB16583.2"
FT                   /translation="MVKVPTYEYYGFVMYLVSMLGFGVYIVWALTPAPVLKFFEIHYYL
FT                   SRWWALAIPTWLFVLVIYIHVVLNAYNTEVLTKPFSSLECIVDQYALVGEEDGAAHGRV
FT                   VDLRLCDVNKQQLEET"
FT   CDS             join(complement(23798..23896),complement(23692..23742),
FT                   complement(22754..23647))
FT                   /db_xref="SPTREMBL:O13905"
FT                   /note="SPAC22A12.14c, len:347"
FT                   /gene="SPAC22A12.14c"
FT                   /product="conserved hypothetical protein; similar to S.
FT                   cereviisae DOS2"
FT                   /protein_id="CAB16584.1"
FT                   /translation="MDLYDYMAPTTTTEEDDEEGYEKLKEEMGSALNNLTNGKFGLFWN
FT                   SMKEKSENFLDDTKGKASSGMQQLKSQLEENIPVNSAMENLRKVEETAGSFWSGFGSTV
FT                   NGFLDQALQISPKEDDVSTPTHEASSSVFLNRHERQLLELVQNENTFTQIISEPSHGIT
FT                   FESWEKEISIDGKTEEISLLLEEYPDLRKQMESLVPSEVSYDDFWKRFFWHKEVVQPIK
FT                   AIQSGNDEEEIFSWGDERSDEEESDNEQVNDEKKQSSEEDTTENNSAAEVIDETVNDLE
FT                   SAVSKGLQIETQPASHDGEVDGEVKEEEENKVSSSSNIEASQSSLEVKDEANRKVDDDD
FT                   EDDDDWE"
FT   misc_feature    complement(23648..23661)
FT                   /note="ctaaccgttcaaag, splice branch and acceptor"
FT   misc_feature    complement(23686..23691)
FT                   /note="gtgtgt, splice donor sequence"
FT   misc_feature    complement(23743..23758)
FT                   /note="ctgacattttatacag, splice branch and acceptor"
FT   misc_feature    complement(23792..23797)
FT                   /note="gtaatt, splice donor sequence"
FT   CDS             complement(24837..26828)
FT                   /db_xref="GOA:P36604"
FT                   /db_xref="SWISS-PROT:P36604"
FT                   /label=bip
FT                   /note="SPAC22A12.15c, len:663aa"
FT                   /gene="bip"
FT                   /gene="SPAC22A12.15c"
FT                   /function="role in assembly of multimeric complexes inside
FT                   the ER"
FT                   /product="78 kd glucose regulated protein homolog
FT                   precursor; hsp70 family"
FT                   /protein_id="CAB16585.1"
FT                   /translation="MKKFQLFSILSYFVALFLLPMAFASGDDNSTESYGTVIGIDLGTT
FT                   YSCVAVMKNGRVEIIANDQGNRITPSYVAFTEDERLVGEAAKNQAPSNPENTIFDIKRL
FT                   IGRKFDEKTMAKDIKSFPFHIVNDKNRPLVEVNVGGKKKKFTPEEISAMILSKMKQTAE
FT                   AYLGKPVTHAVVTVPAYFNDAQRQATKDAGTIAGLNVIRIVNEPTAAAIAYGLDKTDTE
FT                   KHIVVYDLGGGTFDVSLLSIDNGVFEVLATSGDTHLGGEDFDNRVINYLARTYNRKNNV
FT                   DVTKDLKAMGKLKREVEKAKRTLSSQKSVRIEIESFFNGQDFSETLSRAKFEEINMDLF
FT                   KKTLKPVEQVLKDSNLKKSEIDDIVLVGGSTRIPKVQELLESFFGKKASKGINPDEAVA
FT                   YGAAVQAGVLSGEEGSDNIVLLDVIPLTLGIETTGGVMTKLIGRNTPIPTRKSQIFSTA
FT                   VDNQNTVLIQVYEGERTLTKDNNLLGKFDLRGIPPAPRGVPQIEVTFEVDANGVLTVSA
FT                   VDKSGKGKPEKLVIKNDKGRLSEEDIERMVKEAEEFAEEDKILKERIEARNTLENYAYS
FT                   LKGQFDDDEQLGGKVDPEDKQAVLDAVEDVAEWLEIHGEDASKEEFEDQRQKLDAVVHP
FT                   ITQKLYSEGAGDADEEDDDYFDDEADEL"
FT   misc_feature    complement(24903..26720)
FT                   /note="Pfam match to entry PF00012 HSP70, Heat shock hsp70
FT                   proteins"
FT   CDS             join(27839..27862,27922..29376)
FT                   /db_xref="GOA:O13907"
FT                   /db_xref="SPTREMBL:O13907"
FT                   /note="SPAC22A12.16, len:492, SIMILARITY:Caenorhabditis
FT                   elegans., P90731, b0365.1 protein., (1099 aa), fasta
FT                   scores: opt: 810, E():0, (49.6% identity in 423 aa)"
FT                   /gene="SPAC22A12.16"
FT                   /product="putative ATP-citrate (pro-S-) lyase (EC 4.1.3.8)"
FT                   /protein_id="CAB16586.1"
FT                   /translation="MSAKSIREYDGKAVLAYWLNRSPSISKEEYKTVSATPAVQLAQIQ
FT                   FPLPTLVIPAESTTYREVVEDVFAKVEQEHPWVKETKLVAKPDQLIKRRGKSGLLKLNA
FT                   TWDEAKEWIRERAGKNQKVQHAVGYLTTFLVEPFVPHPPNTEYYININSVREGDWILFC
FT                   NEGGVDVGDVDAKARKLLVPVRLSEFPSRATIASTLLSDIPVEQHESLVDFIIRLYSVY
FT                   VDCQFTYLEINPLVVIPTAKGADVFYLDLAAKLDQTAEFECGAKWAVARAPESLGIKTS
FT                   GEESGAINADHGPPMVFPAPFGRELSKEEAYVQGLDAKTGASLKLTILNAEGRVWNLVA
FT                   GGGASVVYADAVAVNGAADELANYGEYSGAPTDGQTYEYAKTVLDLMTRGEPRADGKVL
FT                   FIGGGIANFTSPAVTFRAIARALGDYKDKLHAHKVSIWVRRAGPNYQEGLRVIREAGKK
FT                   FDLPLKVYGPECHISGIVPMGLGKAPVEAEWQMA"
FT   misc_feature    27863..27868
FT                   /note="gtataa, splice donor sequence"
FT   intron          27863..27921
FT                   /note="confirmed intron"
FT   misc_feature    27908..27921
FT                   /note="ctaacggcatttag, splice branch and acceptor"
FT   CDS             complement(29850..30635)
FT                   /db_xref="GOA:O13908"
FT                   /db_xref="SPTREMBL:O13908"
FT                   /note="SPAC22A12.17c, len:261,
FT                   SIMILARITY:Schizosaccharomyces pombe, O74470, short chain
FT                   dehydrogenase., (261 aa), fasta scores: opt: 855, E():0,
FT                   (50.6% identity in 261 aa)"
FT                   /gene="SPAC22A12.17c"
FT                   /product="short chain dehydrogenase; possible sorbitol
FT                   utilization"
FT                   /protein_id="CAB16587.1"
FT                   /translation="MVAPAHNYESRNILDLLSLKGKNAVVFGGARGIGHAICSVFAEAG
FT                   ANAFIVYNTTPGEKAAKEIAQANGVKTYTCKCDVTIPKEVEHAFAEIQKVFDTIDIVVP
FT                   NNGICTGKSAIDMTYEEFANEINVNLLGVFNVAHNAGPIFQKQGHGSLVATASMSGVVV
FT                   NVPQQQCAYNTSKAGVIQLIKSLAVEWRKFARVNCVSPGYTTSDMTGGKFHKEWEPYTP
FT                   FERNGLAKEIASAYLYLASDAASYASGTNLIVDGGYTSI"
FT   misc_feature    complement(29874..29966)
FT                   /note="Pfam match to entry PF00678 adh_short_C2, Short chai
FT                   n dehydrogenase/reductase C-terminus"
FT   misc_feature    complement(30015..30572)
FT                   /note="Pfam match to entry PF00106 adh_short, Alcohol/other
FT                   dehydrogenases, short chain type"
FT   misc_feature    32694..32814
FT                   /note="nominal overlap with cosmid SPAC4C5, EM:Z98560
FT                   S.pombe chromosome 1"
XX
SQ   Sequence 32814 BP; 10360 A; 6118 C; 6176 G; 10160 T; 0 other;
     aattcagaca tggttgactc ctcgttttta accagctcat tttttaaagg ttctaagatg        60
     ttagcatccc caaaagattg ccattgagga gactcaccca cttcagaagt gaaacttgga       120
     tcattgaatt gtaataagac ttcctgtgag aatttctcat tttttatttg ggaacttgaa       180
     attgcatttt ttactgtaga gggcttggtg gtggaatcag ttttttcaac agaaacagct       240
     tcattacccc acatgttttt gccattatta gattttttaa aaaaatctaa aatagacgat       300
     gactttcgtt tactcatttc agtgaacgta aacaaaggca aaattattag ttttttgttt       360
     tttggtgtat aagcaacaac agtaagtgat tgaattcttt taaaggaagt tatttcaaaa       420
     gttgtaaagt ttcgtttagc ttaataatga aagctattat tcgaggaaag acacgataaa       480
     tccgcaagaa tcgcttaaaa gaagtcttga agttaaggaa acggcgagta gacgtcaaga       540
     gcgacttttt ctaatgtaca atgtgtatga gaagtcgtag aatattaggt atgcctttga       600
     aagatcaaaa cgaaaaaaca aaggaaacag atttagaaac tttacctcta actataaatt       660
     tcaaagtatt aaaaagtgtt atggatgaat tattatgtga cgctggatga tccaaaattg       720
     gtcggtcagg atctggtcta aaatgtaaaa aaaagaagta tacctaagga agggtaataa       780
     ctgaaaattg aagtaatgaa aaaaaaagaa aaaaacacct taaaaaaaaa gcatcgatta       840
     ttcacgaaaa tgcgttttat ttacaaaaaa cttcgatttg gagaagctag tgagaaatat       900
     actttcactg cagcttagcg ttccttaatg attttaattt tttttccttt tactttctta       960
     atggcctaca atggcaataa ggcctgttac tgaaaagcct tgcaattgca cagttcaagg      1020
     caaaacactt aaaaaaaacc ctcttggcaa gcataaagta gtcttcgctc aagctcctta      1080
     aaacaaatca tcaacatgcg aaggagtttt aagacaaaca gttagaaaca ggtggtaata      1140
     attataaaaa tcaacttcta cggtaaaaac gatttccttt ttcctttaat aaaagttttc      1200
     gcgatttgac gtgtcgttcc tttaacatat ctcggtcatc acttaaaggc atgtcctcac      1260
     tgttgataca ataaggtctg tcagctagaa aaggatttcg ctttcttttt ctaattgtat      1320
     tgttcctttg caaaggtgga agacatttgt ggattacaaa actgttagaa gaagtatttt      1380
     tacttagacc agcgacaaaa gaatatggag gtggagcttt ataaattgat gtaaacccgt      1440
     caatttcgca ttcttctagt cgaagatttt tattaaagta gtaaggatca gcatccgatt      1500
     ctctgattat ctcaaattgc tccattacca attggtactg cgaattggag ttacaagcac      1560
     atgtaaataa tataagaaca ggcagagagg gaagttactt ataatgtaaa caaacattag      1620
     cgaccacgag gtgaaaaaga tacaaataag aacgtcaata tttctatgac attatacaat      1680
     aaatattatt ttaaatgaat aaaatagatg aactataaaa cagttttttt tttcacattt      1740
     ggtctaagaa ccgtaatgtt gaagaacggt tgcaatttta ttaacataat taggaagatt      1800
     gtttgctttt ccatactctg gcaaaaaagt aatgtatcct tcacattgat cgattgaagc      1860
     attcaatcgt tcttgtatca ccatatcagc aacaactgta tcaacctgtt cctcagaaag      1920
     tttaaagtgt tttgcaagta tagatgtaga agaaacttca aaaaactctg aaagaaaaag      1980
     gatattcgtt tccaaaaaat gtcgaccatc ctctatcaat ctattcatat gaattacttg      2040
     gtgaggaagt agaaaaggca acagaaaggc tccgtcctct tttccgataa actttctttt      2100
     aaggtacttt tcgactagag aataaaacgg gatttctcgg acggatggtt ggagagagat      2160
     ttcttggagg aactgcaaaa caataggaga aggaatcgct agaagtaaac attgagctac      2220
     tgaacacaag ttctctctat aaattagttc atttccaggt actttatatt gaagtacccg      2280
     atagtaacat ttcgcagctt ctaggaattg tcctgtttca tcgagagcgc gagcattgca      2340
     aagttgaagt tccattagca attgatcatt actaacttta aatgccaatg gtatacttgt      2400
     ccttacggtt aaaattgctt tttcagcttt tcctaacttt aaataagcat ctcctaaacg      2460
     aattcttaat aacaagagtt gctctaggtc gttttcaaaa tgaccatgtt tttcgacagc      2520
     ttccaatgaa gaacataaaa gctcaaaatt ttgctcagct tcataaatag tggctaattg      2580
     taaacaacag gaaaccaaat attctgaagg tgcctcctct aacgactgta ctggaacata      2640
     taattcagat attaactctt tccgtaactc aagagacgaa atgctaactg caacatcaag      2700
     taaagaaaac aaaacgtcgt tccgttttgc aaagttgttg ctgccgcaac aaatatttaa      2760
     acatctcttc gcttgctcaa atagctcttt ttcatttgta taatgcaaag ctaatgcttc      2820
     tcgaaactgt gccaccggca tattcccttc caggaaataa tgaactactt cttccatttt      2880
     gatggtttat tgggagaaat aattcagtgg tgggagtgaa tggcttttct tcattgaatg      2940
     tgagtttggt aagagtagca aaatcaaagt ttcgcacctc tagcttaatg gcaatcaact      3000
     aattaaagta tcgtaattta ataattggaa gaagaatatg atttaaatac attattcttt      3060
     caaatttacg caaacataaa tttaaagagt taagaaatgc gtaaagtaac tttgccgcca      3120
     tttttctcta gaattgtaca tattatacat ctcgatttgt ttataaataa aaaagttgac      3180
     gatgtcaact gtattcatta atgatgtttt aattaattta aatgctagaa ttataccgac      3240
     attatttact tttgctttct tcagctgtcg tgtttgttaa gttttaaaat tgatgttgat      3300
     aatgggaaca gtagaaaagt gcacatttat gaaataggtt caactatttt aaaataatct      3360
     aattaggggt cttctctgca atacgggaag atgtcttacc tctcaggatc aactatgtag      3420
     atatgcatac tttttcttca tatctaagat cgattatatt acggaaatta tgagatacat      3480
     aaaaattgaa tataaaagtt tacatttatt gaaacgtaaa agtaacagct tctgttagca      3540
     aattagtcag tacaacaaga aagtttaccc tacattcgat ttccaactct gaaagcaaaa      3600
     atattcaagt ggctttaagc accattttta ctaattcctc tactaccttt tttacactct      3660
     ttaatggaat gttaaaaaat acgaacagtc ttacagtaac tacagcgcaa attgaaataa      3720
     caaagaaggg cttatttatt tttcagttga aaggaaagat aactgagttt aatagaagaa      3780
     accaagaatc tttccaccag cgtccttagc acgagcttcg ttgtgggaca tgataccgcg      3840
     agaggtggtc aaaacaatga caccgacttg acgagagggc aaaagttggt tgacccactt      3900
     ctcaatatcc ttaagcttaa cgttgaaacg gggagagata acaccgcact tgttaatacg      3960
     accattcaac tggataacaa ttttgccaga acggtggtcg tcaatttccg tgaattcgtc      4020
     aatgtagcca tgcttttgca tgacagtcaa aaacttgacg ataaccttag aggaaggacg      4080
     gatgagcact tggcgacgtc cacggcgctc agcgttgacg atattgttta aacaatcagc      4140
     gagaacagat tgacgaacca tttctgcaaa ttgctgctgg tatgagagaa gttttgtttc      4200
     ggcataggag catgtttgtt ctcaaaaaaa gcagtcacat gtctacgaac ataacgtact      4260
     ttagggcata atatgtatat ttccttatat tttgaatggt cattagataa aattcggtca      4320
     agaaaaatac aatttgatgt aattaaatga atgaaagaag aaaacaaaaa ttttcttcgt      4380
     ctttttattc tgtgagcgat ttactttctt gaaatgcaaa actaatgaag agttacagct      4440
     acatccttac gtttatattt taacaaatat attgacattt tcgtaaaatt tcacaaaaca      4500
     aaaatagcgt agattatgaa gttgtcggtt aataatttac ttttaaagtc atgacattgt      4560
     aaacaaccaa tttagtttgc aaaattataa catatggagt aaaccactaa gagggctcat      4620
     cactttatta ttacttgagc tttcataatg cagttttgtc ctacttgtgg aaatcactta      4680
     attgtcgcgg ttgacgagga aggaaggaat gcgttcgact gtagaacatg tccttatcat      4740
     tttccaattt ctacttttct ctacagtcgt cacgaatttg cccaaaagga agttgacgat      4800
     gtattaggtg gagaagaagc ttttgaatct aatcagcaaa ccgaagtcac ttgtgaaaac      4860
     acaaaatgtg acaataatcg tgcttacttc ttccaacttc aaattcgtag tgcagatgaa      4920
     cctatgagta ccttttatcg ttgtaccaaa tgcaaatttc aatggcgtga gaattagttt      4980
     atctattttt tggtttgtta gattttttgc tatcgatggt ggacagtgaa taaactgctt      5040
     gtgtttatcc ttgtgtcttc aatgtttcgt gtaaatatat cttattttta ctttattgtt      5100
     catcacttta taatatgggt tttgcttgga acgtcagact tagttcacaa cttgggtata      5160
     ggtattaggg tcaatatgat ttatttaacc accattattt tttaagtaga ctttcgttga      5220
     tgtttttaat tgattaaact attttctatc tttactctaa ctagttcgta tcgtaagaaa      5280
     aatcataaag taaatgcatt atcaactata agtaattaaa caataacaga tttaaaacca      5340
     aagccctatt tcgtcgaaat taagaccaat tctattacga ggtgcaaacc aaacagacaa      5400
     tattaattat taaagatgta cccgcatctc aaccattaag gaaaatttta caaaaccgtt      5460
     ttacaaccgt tcccacattt gaagcttcat ggttactggt tcgccagagt tatcttggct      5520
     catatgcttt aatcgacttt gaccagtcca ttggcgaatc tgggaggatt tggctttcaa      5580
     ccactccttg ctgtgctcta gaaaaggaag agaaccacta acttgttgag ccgatgattg      5640
     agaaatgaac ttgtcctccg catcagtaat tgcaataata cgtttggtgc aacgacaaag      5700
     cattcccaag gtcagcaatt ttttatcacc gataacgtaa atacgtccaa tggaattttg      5760
     atatgcctct aaatatgcca aagctccttt aaaattagga gtgtaatgaa cgttttcaga      5820
     ataggtatcg ggttcttgtc catcagtaac gaccaaagac aaaaccttag gcccaaatat      5880
     tcttttgtat tcattgaaca tttgcaagtc actgactaca acattaattc ctcccttgaa      5940
     agagcgagac atgatttttg agataagatc gtgctctacg ttattaagag acgtttgagc      6000
     agatgttgta ttcaccttct tggtgggaac gatgagggaa atatgtttgg agataattgg      6060
     ccaatcctct ctcgagaaaa agtcaataaa gtctgcagca ggctcgacat aggcatgagg      6120
     agcaggaatt tggtgggctg ctggatgaaa caatacctgt gcatctttac atgcacgaac      6180
     caacgtggta gaggtttcag tagataaaac tgtgtcgtac tttcccaaaa ggtgaagagt      6240
     gggaagatca agtttggtag catgaacagc accatccatg agaagaggac ggaagtatcc      6300
     actaaagaac aatgcaaacc ggaaaggcgg ttgtgagaaa tattcctggt atttgggtat      6360
     agtaactaaa gcggccaagt tagcagccaa attcgtaccc tgagagaagc caagaatgcc      6420
     atcaaaggga ccgtgctctt taatgtaact ggccaagtac tcaaaagctt tggtaggctc      6480
     aagttgtttg gtatcagcat attcgttaat tctccaccat ccgcgacgat gagatgccgg      6540
     actactagaa aaaacggtag aaagggcgtc aaagccagag ccgttcaatt catctttagc      6600
     tttatctaat tcaataggac cagttgggaa gtagaagtct acactatcag ccatacgctc      6660
     gcgaagagca cgaagcttca cagaaaaaag ttcaccagac tcggcgtaac cgtgaataca      6720
     aagaatcttg gattttgtag cagacttcat tttgagaatg ttgaggagtg agagtgtatc      6780
     tagtcaatga aacagagaat taagaaaaaa ctgtaacgag acttgttaga aggtaagaaa      6840
     atggcaaaag ttgatttata aaacgctttt cagtagatct ttcagcgaaa caaacgaatc      6900
     cacccaatct atttcttcta tactccttat tagagcgcgt tttcttccta tatatagtag      6960
     taggcaaaag aaatctattg aattctaaaa gacaaagaaa acaaagccct tttataatca      7020
     aatcttccac tgaataagcg aacaaatggt tcgatcccac ccaacaaaaa actaggagga      7080
     ggacaacaat caactgatag cctttgtact ataatttctc ttagtgcaat taacgataaa      7140
     aataatgcac tagaacgaaa actaacgaaa cgagttgagt gcttaaactg ttgatcttaa      7200
     ctggcatatc ccccttaaaa aggagttgct gaacaaaacc aggcaaggaa tacttaaatt      7260
     agcgaaatct tttactcatt caaataactc ttcaactgtc atcgcagcag ttaaagcatt      7320
     caaatctcat agtctttgaa ggcaacttag tagtgtatca cgctataaag taattacagc      7380
     ttagtaaata cgagattctt tggaatacaa aggcgtgggt tgtcgacttt tgcaagtagc      7440
     ggtagtatca tatgaatcgc aatagcaaca aaacctagaa caagcaagcg gaagaaatgt      7500
     caaaaactgt gttagcaatg gaaagacggt tttgaacaag gctagcgaat ggtcaaaaaa      7560
     tgtccttcat gagaccaaaa taaaatttct tttgtaccca agtaagaacg acaaaattag      7620
     taccaatttg agactttgta aatattgaac atgcgcactt gcaaatcctt cccacgctca      7680
     gtggctgtct ttttccattt tgaaagaatt aatgtcgatc ttatcaagag cagtcaattc      7740
     atctcgttaa gcaaccgatt atggtatggc caggcttaga caattgggcc gttgcttctg      7800
     ttgcaatgtt caacccgata ttgctgattg tgataataaa tgcaacatta aaagttgcct      7860
     acggtaataa gctgcttata tttcgcccct tattaattga ctcctatgtt ttccctcttt      7920
     tttcttttct ctttcttacg tccatattac attgattaaa actttggcac cgtatctgac      7980
     aataaaagtg catcgttaat agattactaa ctatgataga gctttttagc atcttattaa      8040
     gccattggtt tactttttgc ttagtgcctc tttactttag tggctttctg tttactgact      8100
     gcgtatatag ccataaagtt catttattag tttttagata aataaaaaaa tcaaacttat      8160
     accagtgtac tcaaccgata caaaagtgaa taattagaga aaaagtttca atgaaaaatt      8220
     tttgaaactt ttgaccacaa aagattgaag cgcagaaaat gcgttaggac aacatgttca      8280
     cacattatcc agttaattag aaattgtaat tcttcacgat tgatgggaag ataactctca      8340
     catgttttac tccacacgag cttgagcaga ttcggcaacg ttttcctctt gctcactagc      8400
     aacagattcc ggtgaagaac ctactacttc agtagattca gcggcattat tcaatgcagc      8460
     agcttccatt gccgaacgtt cagcttctac cgatgcacca tcaacagttt cggatgcgcc      8520
     gttgaattca tcagcttcca ttgccaagcg ttcagcttcc actgaagcag ctgcaacact      8580
     ttcagaactg cttgaggcag cagcttccga tgatgagcgt tcggctgcct cagaagcggc      8640
     tttctcagca gcttcgcgtg cctcttgttc cgctttttgc tgggcagcca atttatatcc      8700
     agcctctacc cgttggtccc aagagggata atagtcattc aaatttttgt taagaggagt      8760
     atcaccttcc gacttttttg cggtgtcttc ggagtaaaca aatgggtgag gtgcagcttt      8820
     ttcgaaatat gtttcacccg cgtcagagga aaacttgtaa tcggataaat tgtcaagata      8880
     agtattgcaa tggaagttcc aagatccctt taattctaaa gcacgacaag atgattttgt      8940
     caacgttgtc atatacgtaa atgggctgta aagacggtaa accaagaaca tcaatgccat      9000
     gattatcaca ctcaatgctt tgtaagcagt gcgatttcca aatactgcat taccaaggaa      9060
     agaccaagat acacctagag cagctattcc aaaatacaaa gcaggaagat aatggtaaag      9120
     gaaaacacga tcagtttcca aaatgtaagg agcccaatgc agtaaccatg ctacaacaaa      9180
     tttcccaatg ttgtaattat aatgaaaagc agaaggccca aaatcgttat agcccaaatt      9240
     ccaacgtgct aaacaaaaaa tttgaacgat gacaaagaat gcaactaaag aaattaccga      9300
     ataccaaaca aatgggttac ccataaaaaa gacttgaaga tgctgctcgt agaaaaagcg      9360
     aagaggacca agcaaaagtg gccaagttaa agcgctgctt tcataaacat gtccgtcacc      9420
     catttttcgg tccttcaacc acataagctt gttatgctca acaaagcttt ccaaaaaacc      9480
     gggcttacga taagtaattt ttctagaatc actgggaagc ccatcatgat aattgctttc      9540
     gataaaccac gtggtactgc gctcgacgca gttgcgacaa catgtaacct cacgttgata      9600
     atctccccag tctggaaagc gacgatgaga ggacattaat tcacagttag cgaaaacatg      9660
     gattaatcta aactttgtgt tcaatgtctc aaccgttcca ttgctagtgg catgtttaga      9720
     cttcttctca agaatctgaa tacggaacaa atcatttgcg tccccttcaa atccgaatcc      9780
     accataggcg gaggcctcaa gttgccaatc gttgttgcta actatgggct tgtgttcatg      9840
     agagtgtaaa gcccttccag tcataacatg acgcaagcgt acaacacttc cgtcttttaa      9900
     aagttcaatg ttagaacggt tattgtcctg agaatgttca tgttcaatga tccataaagc      9960
     attttgattt ggttcatcca ccagggatat aatttgttgc tccgtacctt ctggataaag     10020
     gagttcacta gaatgcaaat acccgtgctc agggatggca tttcttattg taaccaaaga     10080
     tccgtaagcc acgtcagcaa attggtcatc aaatctattg ccagccaaag catgtctgtg     10140
     ctcgggtggt aagaaagcat cagcaacgct ggctttatag gcaatatgtg aatggacagc     10200
     aaatacagca agataaaccg taataggaac accaattaaa tagaaaatat acgagaacaa     10260
     gtgtttcaca atacgataca tgggaacgct aagatcacca agcaaattcc aaaggtgaaa     10320
     ggctgcaagt atcaacaacc aaccaaacgt aaacatggca gagagttttg tacttaaagc     10380
     aagaccaaga gcaactcccg tggagagtaa actagtgtgc catctaagac taaaagggcg     10440
     tttttgctgt gcctcataaa cagaccagta aaacgcagtc aaagacatga aatacaatgc     10500
     aggaatttca atcataatgt atctactcat cgtgatcaaa ccattatcaa agataacaaa     10560
     taatgcggca agcgaagccg ctgttttaga ctttgttgga aaataaactg ttccgtacat     10620
     taagggtaca aggagagatc caagtaaaca tgtgaataga cgcatagagt aagcaacatc     10680
     tgtaaaagga tattgctgac caggctcatc caatgtgttc agttcatatt tgttcccagt     10740
     tagagcagca accaaactga agagaagttt acctaaagga gggtagacat ccatcagcag     10800
     tttattgttc acatagtcaa cggcataatt gtaatatctt aactcctcga aaacgacctt     10860
     tgccgggttc atcagtcgtt gagcacgaac acaaaaagcc acaacggtta agaaaataac     10920
     tacaacataa tccaaaaatg aaaatcgctt acgagggcga gaaagcttta catcacgttg     10980
     gattctatgc ttctccttgg gatcctgaaa agtggattgt ttatccatcg cagcctcaaa     11040
     cgatcttgta cagaaaaaag tacctttata gttaaatact aggtaagaat ttctataatt     11100
     gaagaaggat caaagatact gaatttaagg caatacgaag gtttcgtgaa gttgagaaag     11160
     tgttcgcagc aatgtgtaaa ccaagtccat tttcaagtaa cacgataaca tttgcgaccc     11220
     agttttacca aaatgcttat gctctattat tatcatcaat gtaaacctct cttctctttc     11280
     gtcgacaaat tccttttttt ttcctctatc tgtgttgggg actaaaaaat ttcattgatt     11340
     tcaatcaaac gtctaatcat tcatgtaatt gtgcttttca tataaactac ccattttggc     11400
     ttgtcccatc tataaaataa ttcaaagcat tataaaattt attatttttt acttttttaa     11460
     tcattgtagc tttgatttgc ctatatttcg aaacgtattc cgtgaaatgc aataggaagc     11520
     accactagca attgtagtac atccaacaat gtaactaata cagttagtaa aaataatgca     11580
     cttgaaacgc cagtcaagag gaagagatgg gaagaaaaca tgtctttaga ttggggctaa     11640
     aaggtcaacg taaagatatt tactttctta aagttcaggg agactagact tacaataaag     11700
     ggcttttggc aaaagaggca tcaaaaggaa gtatgggctc tgtaatcaaa agtccgagta     11760
     acagcagttg taaagctgta ttccactaat tgtttacaca agtcagtaga taataaacca     11820
     ttacgacata ccttgcttat tctggtaggt tttaattcag tagttggtat cgcaaaatcg     11880
     aaaaatcgtc taaaagtttt aggtgctggc aacgatttat aacgaagata tgagacagcc     11940
     gagacgagca acacatccct tccaataatc aagctagcaa gagttactag ataaggttag     12000
     atattactaa taaacacaaa aagcatacat ggcatagtct cacgcaccgc taaacatatt     12060
     gtcaaacaag tcattaacgt tttatcggct aacggatcaa gtactgtccc agcaatgctg     12120
     cctaaatcaa actttcgagc tatataccca tcaaccaaat ccgtaaatcc agcatataaa     12180
     aaaaagcaag cagcagcttt agtataatca taaatgtaaa gataagcaat taatggagct     12240
     gaaaggagcc ttgagaatgt cagcaagttt ggcaaggtaa aaatattctc acgcaaaggc     12300
     ctttgaatag gcttactgtt attacttttt gtcacagtgt ttaaaacacg agaagaggtg     12360
     tgaaatccac gaacctcgcc cattgacttg ttcaatttgg cagcaggaac gtgtttggat     12420
     agagcccagc gcacaccttc ccatacatta tcagaaacgt gcttcgcaga atatttaggg     12480
     ctattgtctc cttggaagat accagtacgt actaaaatac tagtccaacc gtaattattc     12540
     gcaccacgaa tatcactttc ggggttatca ccaaccatga aaatttcctt gggaggattg     12600
     gtgattccta aagttttatg cttcttcatt aaaatgtttt tagcataatc ataagtcagc     12660
     ttatgaggtt ttccatattt cgtatttctt aagtcctttc cagtaagttc tttaaaaaca     12720
     ctttcacagc aaattgcaaa agctccttga cctaagcggg gaagaggata ctcattaggc     12780
     caaattaaat ccgcactata aaagctgtta gcattcactc atagtattcg agtacagctt     12840
     gcaaaaatat ttttacacaa aagatacttt ccaagaaata acttacttag aaaagtaaat     12900
     atcgggacct tcatttgctg tcttcgaaac tgttcctaaa acaccattct tcgactggcc     12960
     caattccatc accaattgaa gatccaaacc aagtcggaca ggatcgacat aagtgaaaac     13020
     tgcttcaatg ggtctagtaa cgtcaaagtc ttttgcatct ttaatatctt cttcgttaaa     13080
     agatgtgaaa ggccaaaatg gagttcctaa ctttgcgatg acatcgagtt cattgataac     13140
     acttttaaac ccatactttt cagcagtttc acggacgctg ttgtcttttc ctccaagaac     13200
     caagacgtgc ttatacttat ccgcaagagc gcgaaagggg gtatgtgatt gacaaaaatc     13260
     atcctctgtt aaacttacgc tcaatgtctt ggaaagacgc tgagctctaa cactctcatg     13320
     cataccacct ccattcgtta acagaataaa aggtatatta tttttttgca aaaatttcaa     13380
     acttacaagt tagtttgaaa atggtagttc atagttaagc ttacgtcttc gttccttctt     13440
     tcaaacctct tcctcctcta attaaaactc catcaatact gctttggtta gtttcaaaaa     13500
     tcgatcatta attactgtat tactcaaatg cgaaacaaac atctgcaata gggcttttag     13560
     tagacgattc ggtcgtaaac tttcgaaacg ttgaacgccc taactgcctg gcagccaaat     13620
     gccaagatct ataattgata gtatgtagca tttattaaag ccgataaatg aagaatcaac     13680
     aatgtaagaa gtaaaaaatt aagaggtttg tgcggttacg tggtatgaca acttaaggat     13740
     gacggtgggc gggtatgaaa accagacccg catttcctaa gttaaaatcc agctttgttt     13800
     agtgtattgg actttttata ataaagaata tttgtattct caattagttg gagaaagtct     13860
     acaacacctg gtttatttac atcttattta tttcacgagt tgtagaagca aattaactaa     13920
     tagatttcgg cgtcctacga agcttaaata aaataaagta aaaattaaca aaattaaaaa     13980
     aagttctatg aaatctaccg gcgtttattt gtgggagttg ctccccaagc gctctgagta     14040
     gcagcacgtt ttcttcgttc gatttcctct tgagagattt ctaccccgtt ttggacgtca     14100
     aacaaatcag tccgttgact aaccaatctt ttcatatttg cagcaacgtt cacgttctct     14160
     aaatttaaag ttgatttcct agattcttca actttgcgct gttcctgcca gcgagggtca     14220
     agtaatttta gacgcatatg ctcttctagt tctgtagcgg gaaccaattc acctgagaaa     14280
     ggcgatatct ccatcggaac tttgggctgg aaagctaaac agggtcagta aagttacaat     14340
     aaggaatata aacttaccct ttggtactgg cttttgtacc ttcggctgag tagtggtaga     14400
     caaaacggga gaagcttgtg cggcaggaga aactgaagta gttgaagaaa tacctccttt     14460
     ttctggagaa gcaagtgatg gaggaagaga aacaccaaat tcttgttttt taggcgcact     14520
     tatgggctcc caaggctccg ctgtaggagg agcttcctca atagtgtaat tttggtcagg     14580
     catggtaaac atggcagact tttgttctaa agtagcagtt tgtaaatccg ctaaattcgt     14640
     aggtttagct aattttgcat gttcatcgga ctttgtgaat tgaatcactt caacaacgac     14700
     aaaatcgttc caatcaattt gtgcatattc cactaagaca agttagttcc aattcaaatg     14760
     gtaaatgaag aatattggac ttcctgaacc agtttttgca tctcaatata cacttacact     14820
     tctctttttc ggcttcttcc ttttgttttt tcttttggct ctccatatgc gattgccacc     14880
     ttacacgcgg ctgaatttta gaaagtaagc tataagggtc tctcacattt tcacgaagct     14940
     cctgttctgg cgaagaaatg ggctctctaa ttagagaagt atattgttga actatacgca     15000
     taaagtaagg gtacaatgca ttatttggct ttaaaaaatc aaattgagtg ttattccact     15060
     ctttttgaga aagactcact aagaaagaag aaccacgaac tgccgcatat cgcgcagtta     15120
     aacggagcac gtctctagat tcacggttaa ttagcaactt caaagaagaa ggaaataata     15180
     gttgagatga tacttacaaa tctagtgatg aaatagaagg aagtggttct gaaaacaagt     15240
     acggtgaggg agcaggaata gttgcctcta taggtttttg aatgggacga gccaaagtgg     15300
     atgttttttg ggttgacaag cctgtggcat gactcttcaa ttttccctcc ctcgcttcag     15360
     ttaatttgtg ctgataatat gggtggtagg ggtcattagc atgcaagaaa gcaaacttag     15420
     tatttgcctg ttcattctgg cgaatttttt cttcaaaagc tgggccattt ctggcaacgt     15480
     aactagcaga tttatcaatt atttctaagc tacgttagca ggcgcgtcta ttgtactaat     15540
     tactatgact cacctcgaat tgctggagga ggtaaaatta cccctgcagg gaccgatgaa     15600
     ctttgatcag tgatgctttt ttggtgttct gtttcattat ttgtcgtatt tctgtcttgg     15660
     aattccatta aagaactcat atgtgagact tatgcagaaa aaggtagtgg tggaaggaca     15720
     cttgtcgcac aaggcagatg aagcgatgga caagcgaaaa gaaaggacta ttgaaattca     15780
     atagaagttt ataaaagttt agggcgacct tgctgctcta aacagttgtt gcctagggca     15840
     tccgtaatcc actgcggatg gacaaataac atcaaaacgg ttgatagcaa caattatcct     15900
     tacaatttag aatttaaaag atagttatag tgcaagtttt tttgcaagct acattataca     15960
     tttatttatc ggtagaaggt ttatctgcat tcgttgcttt gcctttattt ctacacacta     16020
     agacgcgtaa catgtttacc ctctaccagt actttatcgg agaataagga aaggatatcc     16080
     aggtagtttc tcaagatgca gttaaaccgg aagcagttaa agaatcttca taactataaa     16140
     tatagtgcga ttgataactc acttctttca aaatatattt tgaagccgta ctggtggaat     16200
     caacttttga aggtgattcc catgtctatg gcgtatgatc tacacccgtt tgcttgctta     16260
     ttcttactaa ctctttactt agacctaatt tgattacttt gatcgggctt ggattcgttg     16320
     ttatcaatat ccttactatg cttgtgtaca agtatcatta tgagatggat gctttcccat     16380
     catgggtgta tgcttcttgg gcgattggcc tttttcttta ccaaagtttt gacgctattg     16440
     atggctcgca agcgcgtcgt actggcacat catctccatt aggtcaatta tttgaccatg     16500
     gagtagacgc catcaatacg agctttgaag ttttactgac gattgaactg ctgcaactag     16560
     atatgtttag ctcaatcctt actcaatttg ccagcttatt atacttttac atctctactt     16620
     gggaagaata ccatacgggt actttgtacc tttcatactt ctcgggtcct gtcgaaggaa     16680
     ttgtaatggt tattggacta tttgccctta cagctattaa gggtgattct ttctggctca     16740
     agctacatcc cactcccgag tcatggggat ttgtacgttc ctttctgcca tactacacat     16800
     atggatcatg cttgtacaac tttatggcat ttgccctgct attgaatgtc ttacaaagtt     16860
     tacgaaatgc tcttcaagcc gtccaaaaga acaacggaag tgtgattaaa gcattgagtg     16920
     gtatccttcc ctatttcctc caatggatgg ctgtcttttc actctatgcc aagtatcctg     16980
     ctttctttga acatcatttc ctcactattt tttgcttgaa cgcttttatc tttgcttatt     17040
     cggttggagt ggtaattgtt tctcacatta ccgaatctcc cttcccatac tggaatgtgc     17100
     ttattcttcc attcttggtg gatgccgtgg acgcctatac ttttggcgta ttaaaaaacg     17160
     ttcagacgga atactttttt tgctacgttg gaatttgcat tggtgtttac ggcaactttg     17220
     ttgcacatgt cattgccatg attacggaag agtacggcat taaatgtttg actattccat     17280
     ccaaaccaga gtccaagaag aattgaacta gatgatgatg gtttggacag aatagagatg     17340
     agaacaaaag ggtccagaga gattttgtca ttgataacct ttcggtcgat cttttgttct     17400
     gcaatgtatc taacggatca gaagtatcaa aatgatccat ttcctagtag acaggttttt     17460
     ttcggttgtg tgttttctgc caacaatatg ttacttttgt ttgttttcct gctgtagtaa     17520
     taaaagttgg tttttttacc agaacataat aatgaacaag tatttcactt gcgacttcgt     17580
     tcactaaatg atccagcctt tcgtatcctt ttaactaact gtatatactg atgaacaaat     17640
     ggtccatttg tcttctacac tgcaaacttg cttttcaccg tggaataccg gggctgcact     17700
     aactaagatg actggttcca catgtgcaga ccggagcact tttcgacaac cttcttttaa     17760
     ttaaggttct tatggcagtt cgtaacgatt taacaatttc aataaatagc catcgtcctg     17820
     tcccattgct tctttgggca ttggtagagt ttgccctttt aaggcaatct tttgctacat     17880
     aaaggtgact caagtttacg ctgcgatttt actacttttc tagcatatga tctacaaaag     17940
     gtcagcgaaa tttttctttg actaggaaaa tggattgagg tcatcttcgg caaggcaagc     18000
     tgatatttaa tttaattgtt catatcggca acatttcgta attagttgaa gggtatgaaa     18060
     aacggttcta cggttatcta gatgtgttta ttcactgttt cagcataata tcacttccgt     18120
     tacgtgcggg gcacttcgtc atgcaaattg gtggttatat agtatatata gagagacaag     18180
     gccagcatta ttaaatcgtc ttcaagctcc ctttttccgc tacactcata acttttacga     18240
     aatagcgaaa cgaaaacgag acataacgta acgaaacgaa acgtttacta gtatattctt     18300
     ggtttattta ttttgtattt aaaccagttg aagcatagta gcgtataaag tgttaatttt     18360
     ttcgcattga agggaatttt gatattaata ttttgagatt ttagagacac atagatttat     18420
     ttctttaatc ctttactcac acttgcactt ccccaccacc taaaacaagt cattttatat     18480
     tcttagatca taaatttcgg gaatatttga tttaactatc caacttatat ttaattttat     18540
     tttaaggctt tattctcttt tttttacctt tttcttatta ttctaaaata tggataagca     18600
     ctttatcaac gatcctgaag tcctcgtcct tgatggcctt aaatccttgg ccgacatgaa     18660
     caaaacttta actgttcatg aagagggaaa attcatctat ttccatgact acaacaaaaa     18720
     gaatgtcagt gtcatttccg gcggtggtgc tggtcatgaa cccactcatt cttcgttcgt     18780
     gggcaagggt atgcttactg ccgccgtctc aggctccatt tttgcttctc cttcgtcaaa     18840
     gcaaatttat accggtatta agcaagtcga atctgaggct ggcaccttgg taatttgcaa     18900
     aaactacacc ggtgacatcc ttcactttgg tatggccttg gagaagcaaa gaacggctgg     18960
     taagaaggct gaacttattg ccgttgcaga tgacgtatca gtaggtcgta agaagagcgg     19020
     taaggtcgga cgtcgtggtt tgtctggtac tgttcttgtt cacaaaatcg ctggtgcagc     19080
     tgccgccaga gggttacctt tggaagccgt tacgaccatt gctaaggctg ctattgacaa     19140
     tttggttagt atcggtgctt cactcgctca cgttcacgtc cctggtcatg agccaattgc     19200
     aaaagaagat gaaatgaaac atgatgaaat ggaacttgga atgggtattc acaatgaacc     19260
     tggatgcaag cgtatttccc ctattccctc tattgatgac ctaatcgctc agatgcttaa     19320
     gcaaatgttg gatcaatccg acaaggaccg tgcctatgta aagattgagg gtgacgatga     19380
     agtagtctta cttatgaata accttggtgg tctttccatg cttgaattca gtgccattag     19440
     ccacaaggtg aaggaagcat tggctaaaga atacaaaatc aaccccgttc gcatctttgc     19500
     cggtccattt accaccagtt tgaatggctt gggtttcggt atcactttgc tccgtaccac     19560
     tgaccgcgtc aaagtcgagg gcgaagaata ctctttggtt gatttgattg accaacctgt     19620
     tgaagctatc ggatggcctt tgtgtcaacc ctctgacttg aagtccaaaa acaagattgg     19680
     caatgtcagc atcgaggagg gtcagaagga tgtcaagtct cccgttactg tcgataagga     19740
     gaaggttcgt caggcgattg tcaattcgat ggagaatctc atcaaagcag agcctaaaat     19800
     tacaaagttc gatacgatgg ctggtgatgg tgactgtggt actactttga agcgtggtgc     19860
     tgaaggtgtt ttgaagtttg ttaaatccga caaattctct gacgatccta ttcgtattgt     19920
     tcgtgatatc gcagatgtta ttgaagacaa tatggatggt acatctggtg ctttgtacgc     19980
     cattttcttc catggctttg cgaagggcat gaaagacacc ttggagaaga gcaaggacat     20040
     ttcatctaag acatgggctg ctggtttgaa ggttgctctt gatactcttt tcaagtatac     20100
     tcccgctcgt cctggtgaca gcactatgtg tgatgctctt gttccatttg tcgaaacatt     20160
     tgttaaaact aatgatctta atgctgccgt agaggaggct cgtaaaggtg ctgatgctac     20220
     tgcagatatg caagccaaac ttggacgtgc tgtctacgtt ggtgatgatg ttaaagttcc     20280
     cgatgccggc gctcttggtg tcgttgcaat tgtcgaagga tttacgaaat aattggatac     20340
     gaaatttttt tgggattgta gaattggtat gatcttaaaa actatttacg agcacgaata     20400
     acaattatat tttcattatg catgcattaa ttattgctta cttatctttg catctgtatt     20460
     tgtatattca tgcattataa taagtaattt tttaattaaa acagttgaga aaggacgagt     20520
     gtagatattg tatgaacacg ctgctgtaat aaataaaaga acgacagaaa ttgtatggga     20580
     atattagaca caggcattaa agaagaaaca atacacttta ttcagaaatg gtccctccta     20640
     gataagggca aaccattttt gaattaaacc caattggaca agaattgtta aatagactgt     20700
     gcatattatt caaatttttt tttctgaatc tcgttagagc tttttaataa ggtctttaca     20760
     gtactttatt tgctcttcat cagacatgaa ttcgcaattt ctgatagctg tacaaatgag     20820
     gaccgtagta gaaagatttt cagaattgac ccaaacgcga ccattcattc caacagcaat     20880
     ttcgaaagga atgtagcttc ctagggtctg taaaagtgta tttttaggaa ggatcaactt     20940
     cctacaatga gataaagata aacctgttat catataaccg tttttaagtt caccatatcc     21000
     tgcagctttc cctgtggtag catcgaaaca ttctaactcc ggttccatat cacgatcagc     21060
     gagtgatact cgagcataca caaggcttcc aacatttaaa ttgggcctac ttttacgagt     21120
     cacattttca aaagccaatg cattcaattg agcaatatga gctgacccaa tatctactcg     21180
     ataaccttcc gcaaatctag aaataatttg cccaataact tgatcatttg tagcaggaat     21240
     atatcttttt gtccgtgagt ctatcaacat agcatttttt ccagtttgat gcaacctccc     21300
     agcttttgag accactattt cttcttcacg gtctttcttt tgaaagacta aaccaggacc     21360
     taaacgaatt gatccatcct gactaattat ggagtctggt atccgctcac caggaaagta     21420
     ataagataac agaccttttt cttcaacttc agccatttgg ttaacagaag aaaattagct     21480
     atttggggtt tgatttttcg cgagttatac actataattc gaggattaat gtcttggacg     21540
     gtaagtgtgt ctaaactaat actgtaaatc tcgttaattt tataaatcac attagcccag     21600
     actgtgaaaa ataacgcaaa cgtacattgt gctataatgc tgtttacgag gattttctgt     21660
     atgtatgtcg ttaataggga tatcgaattt aatcacatcg taagcagacg tagttgtatt     21720
     tgtatcatct cagtacgcgc tctcatctaa caaatgcaca tagtaaacac atgtttggat     21780
     gacacttact catcattcca cgttcataaa agggatagag ggttctgctg aaggagagat     21840
     agaagatgta aggcaaacta ctgtttttga tcctccgttt tacggacatc cgatgttggt     21900
     tccaccgtcg ccatctttga ctacgatgtt tcgaacgagg tctacaacgc ctgatgaaga     21960
     gggaactgcc attgcagaaa ttgatcaaca agattgggat ataatggtaa aagttcctac     22020
     ttatgagtat tacgggttcg tgatgtattt ggtgtcaatg ttggggttcg gcgtgtatat     22080
     tgtttgggct ctgacgcctg cgcctgttct caaatttttt gagattcatt attatctatc     22140
     tcgttggtgg gctctagcta ttcctacttg gttatttgtt cttgttattt acattcacgt     22200
     tgtgctaaac gcttacaata ccgaagtatt gactaagcca tttagcagct tagaatgtat     22260
     cgttgatcaa tacgcactcg ttggtgaaga agatggtgct gctcatggtc gagttgttga     22320
     tcttcgccta tgtgatgtga ataaacaaca actggaagaa acttaaaaaa gactaaaagc     22380
     agctaagtga tatcagaatt cattttctcc ttaaaaatct tcattattta agggacttat     22440
     tatctattga tgtcgtcgac ccatacagat ttacttttaa atcctggttt ccttaagttt     22500
     cacaatcaaa aagtatatgt aaatgtataa tattataaga aggttgatta atgctctagt     22560
     cctactactc caacctgcat actcaagatt agatgttttt tatattccgc taataatata     22620
     cctaagagtt gttcgtaaac aaaatgtttt cagacaaata attagctata cgaacaaaac     22680
     acaccaaaac aagtaaatga atagaagaga agtaaaaaca gtatatctct ttttaatagt     22740
     ttgacgagag tcgttattcc cagtcatcat cgtcttcatc atcgtcatca acttttctat     22800
     ttgcttcatc cttcacctca agagaacttt gagaagcttc tatattactg gaagatgata     22860
     ctttattttc ctcttcttct ttaacttctc catcaacctc tccatcatgg cttgcgggtt     22920
     gagtttcaat ttgtaagcct tttgaaactg ctgactccaa atcattgacg gtttcatcta     22980
     tcacttcagc tgctgaatta ttctcagtag tatcttcttc acttgattgc tttttttcat     23040
     cattaacctg ttcattgtca ctttcttctt catcacttct ttcatctccc caactaaaaa     23100
     tttcttcttc atcgtttcct gattgaattg cctttatcgg ctgtacaacc tctttatgcc     23160
     aaaaaaatcg tttccaaaaa tcatcataag aaacttcaga aggtactaaa gattccatct     23220
     gtttccttaa atcaggatat tcttccaaaa gtaaagagat ctcttcagtt ttcccatcaa     23280
     tggaaatttc tttttcccag ctttcaaacg tgatcccatg agagggttca gagataattt     23340
     gggtaaaagt attttcgttt tgaacaagtt ccaacaactg tctctcgtgg cgatttaaga     23400
     aaacagacga agaggcttcg tgtgtaggag tcgatacatc gtcttctttg ggtgatatct     23460
     gcaatgcttg atccaaaaaa ccattcactg tagatccgaa gccactccag aaacttcctg     23520
     ctgtttcttc tacttttcgc aagttttcca tagcagaatt aacaggtata ttttcttcaa     23580
     gctgtgattt taattgctgc attccacttg aggcttttcc ctttgtatca tcaagaaagt     23640
     tttcactctt tgaacggtta gtaacaatgc cattattcgc aatcaacaca ccttttcttt     23700
     cattgagttc caaaacaaac caaactttcc attcgtcaga ttctgtataa aatgtcagta     23760
     aattccgcgc cgtaaatcat cataaaggat aaattacatt tagagccgaa cccatttctt     23820
     ctttcagttt ttcgtatccc tcttcatcat cttcttctgt agtggttgta ggtgccatat     23880
     aatcgtacaa atccattttg aatagtttaa aagaaaactt atgtacttag ttgttagaat     23940
     aagctcacat gtgtttggta gcaaacaagc tatatatgtt gtacttggca gcaagtgaag     24000
     atattgtata gcctaccgaa tagtgacacg attatgctcg tattctgact atggacactt     24060
     atactaactt agtatacttc caataatact ttttaatgaa aaaggcatta cacaatccac     24120
     tacagcttat tttcgtccaa aaaacaaatt ctaagttttt gaagtaaagc aattttaaaa     24180
     tatacacaac accataaaat ttcaccactt tgcacttcga cttaatcaaa tgagatgttt     24240
     taataaatag aatactttta aaactatata taaaaaagct gctactcaca aactcaggta     24300
     agtataaaca ctaagataaa agaacgattg tatttataat aaaaggaatt agtacccaat     24360
     gctataaaat ttgataaaca tacagggtct ttatgattaa ctaccaatta ttgtcagttc     24420
     cacaaagcca ttagcagaag taagcaatac aaagataaca aagcaccagt taactaggtg     24480
     ttgacataca actttgttaa tggctataga gtcacgattc tggtagataa agtaaaatgc     24540
     actttatatc aggtctattt tggagacata ataccatttt aatcatactc aagacgttca     24600
     acaatgaaag agaaacactc atttcaagat agcagaaaca gctcgagaag ctatcaaaat     24660
     gataacgcca tcagaccaca ttaataatca tgagaaaaca ttttgggttt ccaaataacc     24720
     ctttagatta aggtcatgaa acaatgagag catcgagtca gacttgcgta tacttcgaca     24780
     taaataaaat actaagtaaa gcttaaaaat gaaagtacag gcaattttaa aacactttaa     24840
     agttcatcgg cctcatcatc gaagtaatca tcatcctctt catcagcatc accagctcct     24900
     tcggaataca acttttgggt aataggatga acaacggcat cgagtttttg acgctgatct     24960
     tcaaattctt ccttgctggc atcttctccg tggatttcaa gccattcagc aacatcttcg     25020
     acagcgtcca aaacagcttg cttatcttcg ggatcaacct taccacctaa ttgctcatca     25080
     tcgtcaaatt gacctttcaa agaataggcg tagttttcaa gagtattacg agcttcaata     25140
     cgctccttca aaatcttatc ttcttcagcg aattcttcgg cctccttaac catgcgctcg     25200
     atatcttcct cagacaaacg acctttgtca ttcttgataa caagcttctc aggcttaccc     25260
     ttaccagact tgtcgacggc tgaaacagtc aaaacaccat tggcatcgac ttcaaacgtg     25320
     acttcaattt ggggaacacc acgaggggca ggaggaatac cacgaaggtc aaattttcca     25380
     agaaggttgt tgtccttagt aagagtacgt tcaccttcat agacttgaat taaaacagta     25440
     ttttgattgt caaccgcagt agagaaaatt tgcgacttac gagtaggaat aggagtgtta     25500
     cgaccgataa gtttagtcat aacaccaccg gtagtctcaa tacctaaagt aagagggata     25560
     acgtccaaga ggacaatgtt atcacttcct tcctcgccag ataaaacgcc ggcttgaaca     25620
     gcagcaccat aggcaacagc ctcatcggga ttgataccct tagaagcctt cttaccaaag     25680
     aagctctcca aaagttcttg aaccttaggg atacgagtag aaccaccgac aagaacgata     25740
     tcatcaatct cggatttctt gaggttggag tcctttaata cttgctcaac aggcttcaaa     25800
     gtcttcttga agagatccat gttaatctcc tcgaacttag cacgggataa agtttcagaa     25860
     aagtcttgac cgttaaagaa agattcaatc tcgatacgaa cagacttttg ggaggacaaa     25920
     gtacgcttgg ctttttcaac ttcacgcttg agttttccca tagccttaag atccttagta     25980
     acatcgacat tgttcttgcg gttgtaagta cgggctaagt agttgataac acggttgtca     26040
     aagtcctcac caccgagatg ggtatcacct gaagtagcca aaacttcgaa aacaccattg     26100
     tcaatagaca aaagagaaac gtcaaaagta ccaccaccta aatcataaac aacaatatgc     26160
     ttctctgtat cagttttgtc taatccgtag gcaatagcag ccgcagtagg ctcattgacg     26220
     atacgaataa cattcaagcc ggcaatagta ccagcatcct tggtagcctg acgctgagcg     26280
     tcattgaagt aggcggggac agtaacaaca gcgtgagtga caggctttcc gaggtaagct     26340
     tcagcagttt gcttcatttt actaagaatc atggctgaaa tttcttcagg ggtaaacttt     26400
     ttcttcttac cacctacatt aacctcaacc aaaggacggt tcttgtcatt tacaatatgg     26460
     aaaggaaaag atttaatatc cttggccatt gtcttttcgt caaacttacg tccaataaga     26520
     cgcttgatgt caaaaatggt gttttcagga ttggaaggag cttggttctt agcggcctca     26580
     ccaaccaaac gttcgtcttc agtaaaggcc acatatgagg gtgtaatacg attaccctga     26640
     tcgttggcaa taatttctac acgaccattt ttcataacgg caacgcaaga gtatgttgta     26700
     ccaagatcaa taccaataac tgttccatat gattctgtag agttatcatc accactagca     26760
     aaagccatag gtaggaggaa taaagctaca aagtagctta aaatgctaaa tagctggaac     26820
     ttcttcattt tcaataaaca agaatttgaa gattaccaac ttataaatgc ttatatgtgt     26880
     agttcaatta caagagatcg taggcacaag ccaattccca attattgaaa acaacctgtt     26940
     aagtaaatag taaacgggtt ttaatagttt ttgattaaga tttaccaaac tagaatagtt     27000
     ggttttggat gagtttaata gcgtaccaga aatcagctaa gtaacgagag gagcagtcac     27060
     gtcgttaata ctagtacttt ccagaagaat gcagttgaag ctcatcaaca caacaattct     27120
     atagtgagtt ctgtacattt cgataagtcc tattgcgcca ccaccttacg ttttcatagc     27180
     aatgaatgta aacaatgaaa atcgaaattg gtaaattctg aaatgaataa ttgtgaaaag     27240
     aacaaaagca gtgaaggtgg gaaatcttta ttttgatatt gtgttatata gagttatttc     27300
     actatattcc caaatgaaag agaaaaaaaa aaaaaaaaaa attatatata tatttgataa     27360
     tggcctataa atagctgttt taactacaaa tataatggaa aaacgctaaa atatatagct     27420
     aataattaaa attggcttca actgtccgat agtgtcgcat tggttgaatt gtaaaagtca     27480
     tggttaaata aagtataaca tacttgcaaa aggcatcatc tcaaatacga tcatgtttag     27540
     actaaataat attttgcgtt cactttccaa attaatccat taagagaaaa ttatgtagct     27600
     aaaaataatt aaagggtttg tcttttttta tcaatcagca aaagatgata gatcatcact     27660
     tgtatcattg ctcaccattt taacatctca aaatggtata gtccttacat ctgtttacta     27720
     ttattgttgc gacgccgaaa attttgccat aatattttag atctcccact gacaccaaac     27780
     ctcagacctt aacgacacct acccttccct tggcacaatt tttaattaaa gcacgaagat     27840
     gtctgccaag tcaattagag aggtataagc ttgttaaata ttaaaatttt attttcttcg     27900
     cattttgcta acggcattta gtatgatggt aaggctgttt tggcctattg gttgaacaga     27960
     tcgcctagca tctcgaaaga ggaatataag actgtttctg ccactcctgc ggtgcaactt     28020
     gctcaaattc agtttcctct ccctaccttg gtgatccctg cagaatctac tacttacaga     28080
     gaagttgtcg aagacgtttt cgccaaggta gagcaagaac acccttgggt caaggaaacc     28140
     aagttggttg ctaaacctga tcaacttatt aaacgtcgtg gtaaaagcgg tcttttgaag     28200
     ttgaatgcca cttgggatga agccaaggaa tggatcagag aacgtgcagg aaaaaatcaa     28260
     aaagttcagc atgctgtagg atatttaact actttcctgg ttgagccttt tgttccccat     28320
     cctcccaaca ctgagtatta tatcaatatt aactcagttc gtgaaggtga ttggatattg     28380
     ttttgcaacg aaggtggtgt tgatgttggc gacgttgacg ctaaggctag gaagctattg     28440
     gtacctgttc gccttagcga gttcccatct cgtgcaacca ttgcttccac tcttctatct     28500
     gatattcccg ttgaacaaca tgaatccctt gttgatttca tcattcgcct ttattcagtg     28560
     tatgtggatt gccagtttac ctacttggaa atcaatccct tggttgttat ccccactgcc     28620
     aaaggtgccg atgtctttta cttggatttg gccgccaagc ttgatcaaac cgcagagttt     28680
     gagtgtggtg ccaaatgggc agtcgctcgt gctcctgagt ctctcggcat taaaacatct     28740
     ggtgaagaat ctggagctat taatgctgat catggacctc caatggtctt ccctgctcca     28800
     tttggtcgtg aactgagtaa agaagaagct tatgtacaag gacttgatgc caagactggt     28860
     gcttctctta agctcactat cttgaatgcc gaaggccgtg tttggaactt ggtggctggt     28920
     ggtggtgcct cagttgttta tgctgatgct gttgctgtta atggtgctgc cgatgagttg     28980
     gctaactacg gtgaatatag tggtgctcct actgacggcc aaacttatga atatgccaag     29040
     actgtgctcg acttgatgac tcgtggtgaa cctcgcgctg atggtaaagt attgttcatt     29100
     ggtggtggta ttgccaactt tacctcacct gctgtcacat tccgtgccat tgctcgcgcc     29160
     ttgggtgact acaaagacaa attgcacgca cataaagtct ccatctgggt tcgtcgtgcc     29220
     ggacctaatt atcaagaagg tcttcgtgtg atccgcgagg ctggcaaaaa gttcgatctt     29280
     ccattgaagg tgtacggacc agagtgccac atcagtggta ttgtacctat gggtttgggt     29340
     aaggcacctg tggaagctga atggcagatg gcttaaataa ttagagttag tgcttcagta     29400
     gttttttgtg tatggtaata aatctctgca atattagtca tgcaaaacgt atacgtatag     29460
     aggtgacggt tcattagtgc aaggggagtg aattgagtaa ttaaaaaaag ctgtggacta     29520
     ctagtacagt ggagatagaa gttaagattg aagtgaaaaa gaatgtaaaa ggatgattta     29580
     ttatccaacg agtgagtaaa aagagaggtt ggcaaaacaa tcagtatatt taaaagaaaa     29640
     atacaaagga taagctatta ttgatgaata gagagaatga aatgtataac ggaattttgt     29700
     tgaggactat acggtagtat gggtaactat gggatcataa atgcatgctt aaatactcat     29760
     aaagactgag aagtaacatt cgtaatgttt tgaaaagggc atccatcata tactagaaaa     29820
     caataattac aaaaagtcat caaactccat tagatgctgg tatatccacc atcaacgatt     29880
     aagttggtac cggaagcgta tgaagcagca tcactagcaa gataaagata agcggaagca     29940
     atctctttag ccaaaccatt acgctcgaaa ggagtataag gctcccattc cttgtggaac     30000
     ttaccaccag tcatgtcact agtagtgtaa ccgggagaaa cgcagttgac gcgagcaaat     30060
     ttgcgccatt cgactgccaa actcttgatg agttgaatga caccggcctt ggaagtgttg     30120
     taagcacatt gttgttgagg aacgttaaca acaacaccag acatggaagc agtagctaca     30180
     aggctgccat ggccttgctt ttggaagatg gggccagcat tgtgagcgac gttgaagaca     30240
     ccgagcaagt tgacgtttat ttcattagca aattcttcgt aagtcatgtc aatggcggac     30300
     ttgccagtgc aaataccgtt gttgggcaca acgatatcaa tagtatcaaa gaccttttga     30360
     atctcagcaa aggcatgttc tacctcttta ggaatagtga catcgcactt gcatgtataa     30420
     gtcttgacac cattagcctg ggcaatttcc tttgcagcct tttcgccagg agtggtgtta     30480
     tagacgataa aggcattggc gccagcttca gcaaacactg agcagatagc gtgaccaata     30540
     ccacgggcac cgccaaagac gacagcattt tttcccttta atgaaaggag atctaagata     30600
     ttgcgagact cgtaattatg agcaggagcg accattttgt agtaataaaa attcaatcaa     30660
     agttttatta agattttttg aatgttttct tccaattggg accgataaac acaatggaca     30720
     gagaagagag aactaaacta ctgtttataa aattccttgc aattgaggaa agaaatgtca     30780
     gcgttaagtg aattacaaaa taagcaggat ttcagcgcca ttttataata tttttggaga     30840
     gtcgtgacgt tgggaaaaag ctctttttat tttttatttt gtttttcagg tagtgttctg     30900
     gctcccgcgc acaacgacca gttcgtcaaa aactgacaaa attccttcct gcaacattac     30960
     gataacattt aattaacatt ttgctgtatc acattacata acactaacgt caattagcgg     31020
     atcgaaaaaa ggtctgatac aaggaccagc tttgggtgta tggaattgcg tcatcttttg     31080
     gtgtagcatt ttgaagatcg gcaatacact gctgtataga gttgagtata cggggccaag     31140
     agatgtgcaa agcgccgtct atcgtactac cgtataattc cagtatggaa gaagcaaaga     31200
     cattggaata aggtaataaa gacatcccag cttgaaacaa aacaattgaa tgtgatgctt     31260
     gcacgaagca gaaatcgttg aattggtgtt gacgtggaag tgtacaaaag aggataaata     31320
     acaagtggta aacttcaaat cacaagctta ggtttgatga aacaaggagg gatgagatga     31380
     aaagcaatat actataaaca taacagttgg gaaaccaatt atataatact taatacaaat     31440
     acagattcta caacaaataa acaaaaaaaa atttttaatt agtttcaaaa acgctaattc     31500
     atacaggtga ctagttactt gatcagtttc actactttgc ttattagact aattagattc     31560
     aaggtgttta agtagcattt ttatttactg gagatggttg tcttactttc acaaagatta     31620
     tattatattt taactttctt tcaaactttt cctttgcatt gattgggaag taataccttg     31680
     tctcttccaa acggagagag ctaatcatcc atctgtcttt gttttgtaat tcaattaatg     31740
     attgatttat ctttctccct ttttctttct ttcattctgc gatgacgcta cactacacta     31800
     tagcggatcg ttttgatgga aattttcgtg tatacgtaga ttgtaatgag tctacggagt     31860
     ctagtcgact aaattaatta gaaagctgtg ttttgctttg tgacggtagc ttttaagtga     31920
     tattgattat tcatcataac agaaaccgaa tgttgctatg gtatcacttg aacggtatga     31980
     gttcagattg cactctaata aaaaagggga gactttgcta agtatgttta gatagatgat     32040
     acacatttga tgccatagct ggtaaggtgg attatcccta tttagaatga aggttcaaaa     32100
     tccatttttt ataatgaacg gttatatcca gctattgagt agcatcgatt ttgttcgttg     32160
     aaaaaaatac atatcaattt ttggtatttt ggtgcttgat tattttttta ttagctgaat     32220
     tttttgttat ttggaattta ttgttttctg tttgctttac ttgcctgcta aagttcattc     32280
     acagcagccg gttgtgaagt aaattggaaa agaaactgaa aagaatttca ttgctttttt     32340
     atttatgatg tatgcaatgc actcgatttg taagcaattc tgtgtttgta ttctttgttt     32400
     ggctgaagct ctagttaagc catattgttg ggcctaagta aattaaattt tcaaaaaaaa     32460
     attaataggc tgtaactaaa taaagagaaa ataaagaaaa tagataataa aaaatatgaa     32520
     aacagtttaa ctaaaaatat agacagtagt cttatgatac tttatagaat cttgtgatat     32580
     ttttttgtat ttaccctttt ttttatttac acttggcttc tttcaacaat ccactcgttt     32640
     caactgcttt gctcgacgca ctcattacaa aatcctacaa attcccatgt aaccggagcc     32700
     gcatgaggag actttcaaaa atgttttatc tttgttttct gtcctcacgg caatctgcat     32760
     ttgttattta ttgctgtgtt aaatatccat atttttcgtc atccggcaaa gatc           32814
//