ID SPAC227 standard; DNA; FUN; 32799 BP. XX AC AL133156; XX SV AL133156.1 XX DT 18-NOV-1999 (Rel. 61, Created) DT 08-DEC-2001 (Rel. 70, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c227. XX KW cleavage and polyadenylation specificity factor; KW folylpolyglutamate synthase; G-beta repeat; gim complex component; gim3; KW gim4; mitochondrial carrier protein; Mur_ligase; NifU-like; pab1; KW protein phosphatase pp2a regulatory subunit b; saccharopine dehydrogenase; KW U4/U6 small nuclear ribonucleoprotein; WD40. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-32799 RA Zimmermann W., Wambutt R., McDougall R.C., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (18-NOV-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Agowa GmbH, Glienicker Weg 185, D-12489 Berlin, RL Germany XX DR GOA; Q09694; Q09694. DR GOA; Q12702; Q12702. DR GOA; Q9UTC5; Q9UTC5. DR GOA; Q9UTC7; Q9UTC7. DR GOA; Q9UTC8; Q9UTC8. DR GOA; Q9UTC9; Q9UTC9. DR GOA; Q9UTD0; Q9UTD0. DR GOA; Q9UTD1; Q9UTD1. DR GOA; Q9UTD4; Q9UTD4. DR GOA; Q9UTD6; Q9UTD6. DR GOA; Q9UTD8; Q9UTD8. DR SPTREMBL; Q9UTC2; Q9UTC2. DR SPTREMBL; Q9UTC3; Q9UTC3. DR SPTREMBL; Q9UTC4; Q9UTC4. DR SPTREMBL; Q9UTC5; Q9UTC5. DR SPTREMBL; Q9UTC6; Q9UTC6. DR SPTREMBL; Q9UTC7; Q9UTC7. DR SPTREMBL; Q9UTC8; Q9UTC8. DR SPTREMBL; Q9UTD0; Q9UTD0. DR SPTREMBL; Q9UTD1; Q9UTD1. DR SPTREMBL; Q9UTD3; Q9UTD3. DR SPTREMBL; Q9UTD5; Q9UTD5. DR SPTREMBL; Q9UTD6; Q9UTD6. DR SPTREMBL; Q9UTD7; Q9UTD7. DR SPTREMBL; Q9UTD8; Q9UTD8. DR SWISS-PROT; Q09694; LYS1_SCHPO. DR SWISS-PROT; Q12702; 2ABA_SCHPO. DR SWISS-PROT; Q9UTC9; PFD2_SCHPO. DR SWISS-PROT; Q9UTD4; PFD4_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c227 is overlapped at the 3' end by cosmid c2F7, EMBL CC entry SPAC2F7, accession number Z50142. XX FH Key Location/Qualifiers FH FT source 1..32799 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c227" FT /map="IL" FT CDS complement(1..987) FT /db_xref="GOA:Q9UTD8" FT /db_xref="SPTREMBL:Q9UTD8" FT /note="SPAC227.01c, len:329, SIMILARITY some FT to:Schizosaccharomyces pombe, YAT5_SCHPO, hypothetical FT protein c1d4.05c, (387 aa), fasta scores: opt: 300, FT E():3.9e-13, (25.2% identity in 361 aa)" FT /partial FT /gene="SPAC227.01c" FT /gene="SPAPB21F2.04c" FT /product="possibly required for retention of luminal ER FT proteins; similar to S. cerevisiae ERD1" FT /protein_id="CAB61450.1" FT /translation="MALIEDLNHFINYFPLVLRLFFLVVFGLYSFTLILHLLVINRVDV FT FSLLHTPLPVNRSQQANAPLWQLSFSLSILGTLLFVIAESLYLISGSDELAYVPVFIFG FT VIVFMPVHKFWFFQRKVFTRQCLRILGGSYRPDYKFPDVIFSDLLTSYSRVIADLWLAG FT AILIYVTDSPNNSHRKQYENEVIMSMIAAYPYAIRFRQCLIERSSADNSSDKFWSTLNS FT IKYFTAFPAIFLGIFAKKRFSFLWFLWNTSSAINSTYSFWWDVSMDWSLPFFKQPLSIQ FT NWKFGVRRLFPTFTFAVVSAIDFVLRMAWVVRVLPEHQSAFFTTDFGI" FT misc_RNA 1387..1806 FT /note="mRNA from AU006865 not associated with an ORF" FT CDS complement(2349..2966) FT /db_xref="SPTREMBL:Q9UTD7" FT /note="SPAC227.02c, len:205, SIMILARITY: Saccharomyces FT cerevisiae, Q06511, hypothetical protein (250 aa) fasta FT scores, opt: 252, E(): 7.7e-08, (26.4% identity in 193 aa FT overlap)" FT /gene="SPAC227.02c" FT /product="eukaryotic conserved protein; similar to S. FT cerevisiae YPR143W which is null lethal; putative FT coiled-coil region" FT /protein_id="CAB61451.1" FT /translation="MAKSQRSQIKNEDISFVSQEDDSSKKFVKDDSENSEEELEDLNSE FT DEFYQSNSSEDEIEEEVQESTIADDIADILNQQVTQTDEQDTPVLSLSKKSKKALRKSN FT AEKKDSKLRTSRRRERLRKEMVGRVTSVVAVNAETAKALFTHERELRRIARRGVVQLFN FT AVRTAQLQSSLNRENISGGRTAREQKVKELSKASFLDLIKSQ" FT CDS complement(3560..4675) FT /db_xref="GOA:Q9UTD6" FT /db_xref="SPTREMBL:Q9UTD6" FT /note="SPAC227.03c, len:371, SIMILARITY:Saccharomyces FT cerevisiae, YIA6_YEAST, putative mitochondrial carrier FT yil006w., (373 aa), fasta scores: opt: 405, E():7.9e-20, FT (37.8% identity in 373 aa)" FT /gene="SPAC227.03c" FT /product="MC transporter of unknown specificity" FT /protein_id="CAB61452.1" FT /translation="MVDDSLKDAIAGGAAGLASSLVVAPLDVVKTRKQAQKAFYSTGGG FT KNTMVLGGTLSSMRTIFHNEGIAGLYRGVGPMMLGYLPSWSIYFVVYEKCKVLFGVNKK FT YTSLHEIDSSKVGIKASLDSSDKQFYRYWGGQIFSAVIAGAASVTLTNPIWVVKTRLVT FT QSHPRASSFVDKIAAATTVQFRNLQTDAPSVKWRMPRFWLKRRTNVKSSPSQHPVNPPT FT GPACSPAYNNTFDAFRKIYKYEGLAAFYRGLFPSLFGTLHVGIQFPLYEYFKSFLDDFF FT GKKSNFHIVLAATLSKIAASTVTYPHEVLRTRLQSLDAPTHNSATLLIRDIWRSEGWRK FT YYSGMATNFIRTIPASSVTFLSFEIVRKWLN" FT misc_feature complement(3566..3994) FT /note="Match to PF00153 mito_carr, Mitochondrial carrier FT proteins Score 138.34" FT misc_feature complement(4166..4660) FT /note="Match to PF00153 mito_carr, Mitochondrial carrier FT proteins Score 138.66" FT CDS 5635..6174 FT /db_xref="SPTREMBL:Q9UTD5" FT /note="SPAC227.04, len:179" FT /gene="SPAC227.04" FT /product="hypothetical protein; sequence orphan" FT /protein_id="CAB61453.1" FT /translation="MSFKSQLLILAQKLSKGGISCELIEFDECILKLEWHTELLDKNDS FT LLYEQEEDDILSLMNPMITMHAWIRDSPSFEVPQFFFQPYANGSDPLTKMEQIFELLEG FT SSQNLAYDALAIGDCPGTVGIAWYIHPCRTRDYFEMLQIDKEDPKYLSLWLLYIHQVLS FT PLTQPIIKAVDDAEKS" FT CDS 6566..6937 FT /db_xref="GOA:Q9UTD4" FT /db_xref="SWISS-PROT:Q9UTD4" FT /note="SPAC227.05, len:123, SIMILARITY:Caenorhabditis FT elegans., Q17435, hypothetical 14.0 kD protein b0035.4 in FT chromosome iv., (126 aa), fasta scores: opt: 230, FT E():8.4e-08, (34.4% identity in 122 aa)" FT /gene="SPAC227.05" FT /product="putative GIM complex; prefoldin subunit 4" FT /protein_id="CAB61454.1" FT /translation="MEQVPVLAEDQRNLNEFSVLHSRKAIQELDIKNLKTQIEDIVDAK FT NECELLDEDDGDDIPALKVGDAFFQVSLPVLLDQLEQSEESLEKQVDVLRSSMEKDETR FT IQELKSMLYSKFHDQINLD" FT CDS 7125..7874 FT /db_xref="SPTREMBL:Q9UTD3" FT /note="SPAC227.06, len:249, SIMILARITY:Caenorhabditis FT elegans., AAD12839, y25c1a.7b protein., (287 aa), fasta FT scores: opt: 335, E():4.1e-15, (31.0% identity in 203 aa)" FT /gene="SPAC227.06" FT /product="conserved protein; similar to S. cerevisiae FT YGL161C, S. cerevisiae YGL161C is predicted to be involved FT in vesicular transport and membrane fusion from 2-hybrid FT data" FT /protein_id="CAB61455.1" FT /translation="MAHEIEIDSEADLGRTTFEAEDLYKQRTPITKPPAPRLQSRRASM FT QETPWTIKDSFNVETKDVVQRCIHTLIPTVNFFDVVDDRPDLYGPFWITTTVIQALFFS FT NSITEYARYATGHGTSGYSIKKLISAASIIYGYTTIIAVLLWGILVWNKCNPKLLDCLC FT LYGYANIVWLPVSLATPPFGLLSTLASHIVKYVLTGIGLLISIVFLTRNLYPICQQAGS FT NLCKLLLFGIIVFHCLLALSLQLIFFS" FT CDS join(complement(10230..10273),complement(10145..10185), FT complement(8785..10067),complement(8718..8741)) FT /db_xref="GOA:Q12702" FT /db_xref="SWISS-PROT:Q12702" FT /note="SPAC227.07c, len:463" FT /gene="pab1" FT /gene="SPAC227.07c" FT /product="protein phosphatase pp2a regulatory subunit b" FT /protein_id="CAB61456.1" FT /translation="MDDIEDSLDQWKFAQCFGDKGDVEDITEADIISAVEFDHTGDYLA FT TGDKGGRVVLFERNHSKKGCEYKFFTEFQSHEPEFDYLKSLEIEEKINKIRWCKRTNRA FT HFLLSTNDKTIKLWKLYEKNLKVVAENNLSDSFHSPMQGPLTTPSQLRLPRLNHHDMII FT AAYPRRVYANAHAYHINSISVNSDAETYISADDLRINLWNLSISDHSFNIVDIKPENME FT ELTEVITSAEFHPINCNHLMYSSSKGNIKLLDLRQSALCDNPCKLFEDQEDQDSKSFFS FT EIISSISDVKFSQNGRYILSRDYLTLKIWDVNMEKAPVKTIPLHDVLRSKLCDLYENDC FT IFDKFECTFSGDDKHVLSGSYSNNFGIYPTDSSLPGDRGQIVLQADKAAFRARKSAANN FT VPKLNAVKNNDWRSQPQAAMGSASVGLDPDNLDYNKKILHASWHPFEDSVAIAATNNLF FT VFSKL" FT misc_feature complement(8742..8756) FT /note="ctaatgtttcaatag, splice branch and acceptor" FT misc_feature complement(8779..8784) FT /note="gtacgt, splice donor sequence" FT misc_feature join(complement(10145..10184),complement(8785..10067)) FT /note="Match to PF01240 PR55, protein phosphatase 2A FT regulatory subunit PR55 Score 849.23" FT misc_feature complement(10068..10080) FT /note="ctaacaagtttag, splice branch and acceptor" FT misc_feature complement(10139..10144) FT /note="gtattg, splice donor sequence" FT misc_feature complement(10186..10197) FT /note="ctaactctttag, splice branch and acceptor" FT misc_feature complement(10224..10229) FT /note="gtatgt, splice donor sequence" FT CDS join(complement(11749..11918),complement(11362..11652), FT complement(11251..11302)) FT /db_xref="GOA:Q9UTD1" FT /db_xref="SPTREMBL:Q9UTD1" FT /note="SPAC227.08c, len:170, SIMILARITY:Mus musculus, FT O54930, clipper/cleavage and polyadenylation specificity FT factor 30 kDasubunit homolog, (208 aa), fasta scores: opt: FT 526, E():6.6e-25, (53.1% identity in 128 aa)" FT /gene="SPAC227.08c" FT /product="putative cleavage and polyadenylation factor; FT similar to S. cerevisiae YTH1" FT /protein_id="CAB61457.1" FT /translation="MTDYIKDKAIAADFSSVQFRFDNYLKQNFNFGRSALLNSGNGRDS FT GSKMGSVVCKHWLRGLCKKGEQCDFLHEYNLKKMPPCHFYAERGWCSNGEECLYLHLDP FT SKQVGVCAWYNMGFCPLGPICRGKHVRKPRPCPKYLAGFCPLGPNCPDAHPKHSEPPHP FT PQKRKDW" FT misc_feature complement(11303..11316) FT /note="ctaacatgttctag, splice branch and acceptor" FT misc_feature complement(11356..11361) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(11653..11667) FT /note="ctaatattatataag, splice branch and acceptor" FT misc_feature complement(11743..11748) FT /note="gtatgt, splice donor sequence" FT CDS 12389..13642 FT /db_xref="GOA:Q9UTD0" FT /db_xref="SPTREMBL:Q9UTD0" FT /note="SPAC227.09, len:417, SIMILARITY:Saccharomyces FT cerevisiae, FOLD_YEAST, putative folylpolyglutamate FT synthase, (427 aa), fasta scores: opt: 924, E():0, (39.9% FT identity in 431 aa)" FT /gene="SPAC227.09" FT /product="putative folylpolyglutamate synthase" FT /protein_id="CAB61458.1" FT /translation="MPIQLGLQRMLQLLKHLGNPQESFCAVQIAGTNGKGSICSYIYTS FT LLQAAIKTGRYTSPHFLEPRDTISINGQIASEEIFNTCWKQVIEVDRRFRTKATEFELL FT TATAFQCFHHSGVRVAVIETGMGGRLDATNVFEEPVLSIISRICLDHQAFLGNTLEAIA FT KEKAGIFKKNVPCVVDGLNEVNVLNQLKLSAEETRAHPFYLAKGKSGENKNEWIINTPN FT WGTNTFSTPLKGDYQGQNLACAVTALDILSSSFSIMLPHVQNGVKNTSWPGRLDIRSVP FT SLGDILFDGAHNKEAAIELAKFVNSQRREHNKSVSWVVAFTNTKDVTGIMKILLRKGDT FT VIATNFSSVSGMPWIKSMEPEVIKNSISSESSVECYTADNLTISEILRLAKEKNSSVIV FT CGSLYLLGDMYRYLKLDV" FT misc_feature 12473..13267 FT /note="Match to PF01225 Mur_ligase, Mur ligase family Score FT 42.96" FT CDS join(14413..14440,14490..14580,14628..14751,14826..14927) FT /db_xref="GOA:Q9UTC9" FT /db_xref="SWISS-PROT:Q9UTC9" FT /note="SPAC227.10, len:114, SIMILARITY:Saccharomyces FT cerevisiae, YEA3_YEAST, hypothetical 14.3 kD protein in FT gcn4-wbp1 intergenic region., (123 aa), fasta scores: opt: FT 301, E():6.6e-14, (43.3% identity in 104 aa)" FT /gene="SPAC227.10" FT /product="putative GIM complex; prefoldin subunit 2" FT /protein_id="CAB61459.1" FT /translation="MAEQPSRQQILQTQYNSYKSRLQQIAQKIVDLETDADEHKLVMDT FT LNSMDNNRRCFRMIHGVLVERTVGTVVPILKTTQEGIQTAMNGLLDQYKQLEAEFQKFQ FT KDNKIQVVRQ" FT misc_feature 14441..14446 FT /note="gtatgt, splice donor sequence" FT misc_feature 14476..14489 FT /note="ttgaccagttccag, splice branch and acceptor" FT misc_feature 14581..14586 FT /note="gtatgt, splice donor sequence" FT misc_feature 14616..14627 FT /note="ctaactaaaaag, splice branch and acceptor" FT misc_feature 14752..14757 FT /note="gtaagg, splice donor sequence" FT misc_feature 14810..14825 FT /note="ctaatcaaaatattag, splice branch and acceptor" FT CDS join(complement(16116..16241),complement(15804..16064), FT complement(15139..15664),complement(15016..15071)) FT /db_xref="GOA:Q9UTC8" FT /db_xref="SPTREMBL:Q9UTC8" FT /note="SPAC227.11c, len:322" FT /gene="SPAC227.11c" FT /product="hypothetical protein; similar to S. cerevisiae FT YDR057W" FT /protein_id="CAB61460.1" FT /translation="MFPHLILPAIGSSKVRTMVLPFAFVGFFIFPICLASLLDWNDAYE FT YPKYSFEWSNVSILEGDIDSIKEKTEKTKLSSLFYAGKHEYFCVYPNASLIKQNSTTEP FT SYDLQELRIQGTEKINELANVFLIENRGYWTYDYVYGQHVRQYHLEPQQGSDKVLANPM FT YILGTAPNTQTKKNLEENWAIGFVEGKAYLQTTFRNGTMCDITKRPRHVILSYECSTNS FT DTPEITQYQEVSSCAYSMTIHVPGLCSLPAFKIQEDIPSEKIVCYNVIKEKSNEVDHKD FT SQHVVDEVAQTSPPEVKEVETQSMMIFDDTNTLGFYPCSSV" FT misc_feature complement(15072..15085) FT /note="ctaataacataaag, splice branch and acceptor" FT misc_feature complement(15133..15138) FT /note="gttagt, splice donor sequence" FT misc_feature complement(15665..15680) FT /note="ctaatcattgtattag, splice branch and acceptor" FT misc_feature complement(15798..15803) FT /note="gtacga, splice donor sequence" FT misc_feature complement(16065..16084) FT /note="ctaacggacttcctttgtag, splice branch and acceptor" FT misc_feature complement(16110..16115) FT /note="gtatgc, splice donor sequence" FT CDS join(16379..16415,16478..17829) FT /db_xref="GOA:Q9UTC7" FT /db_xref="SPTREMBL:Q9UTC7" FT /note="SPAC227.12, len:462, SIMILARITY:Caenorhabditis FT elegans., Q93339, c36b1.5 protein., (496 aa), fasta scores: FT opt: 1076, E():0, (37.6% identity in 442 aa)" FT /gene="SPAC227.12" FT /product="putative pre-mRNA splicing factor; WD repeat FT protein" FT /protein_id="CAB61461.1" FT /translation="MNENEGISLGELETRPFSEGITRFTKEQAAYYAEQKEKDRIKALK FT IPYEDSKVREYLRRYGEPITYFGEDALARRQRLQQLMIEKSLEGDNPLDVDQGASENIE FT KETYVQGSHELLVARKKIALYSLEKAKLRLKKEREISEIPVPEIVLSGKSSIEHLQKAE FT LMGSQIGGERPIAIVRFSNNGNHFASGSWGGQVKVWNSDNLSEVQLFRGHTDRVSGLDW FT YPLCQAWDADSEQLTLATGAADNTVCLWKASQSTPLLRLEGHLARVGRVAFHPSGDYLV FT SASFDTTWRLWDVHTGVELLMQEGHSEGIFSIACQPDGSLVSSGGNDAIGRIWDLRSGK FT SIMVLDEHIRQIVAMAWSPNGYQLATSSADDTVKIWDLRKVSLAHTIPAHSSLVSDVRY FT IESGVNRFIATSGYDGCVKLWNPLNCSLIKSMVGHEEKVMSVDGYGDRFISSGYDRTIK FT LWYP" FT misc_feature 16416..16421 FT /note="gtacgt, splice donor sequence" FT misc_feature 16461..16477 FT /note="ctaataaaaaactttag, splice branch and acceptor" FT misc_feature 16945..17040 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 26.51" FT misc_feature 17059..17193 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 30.93" FT misc_feature 17221..17319 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 33.09" FT misc_feature 17350..17445 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 29.15" FT misc_feature 17482..17571 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 34.76" FT misc_feature 17587..17703 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 37.72" FT misc_feature 17713..17820 FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 35.98" FT CDS complement(18447..19025) FT /db_xref="SPTREMBL:Q9UTC6" FT /note="SPAC227.13c, len:192, SIMILARITY:Saccharomyces FT cerevisiae, Q03020, lpi10p., (165 aa), fasta scores: opt: FT 661, E():0, (64.7% identity in 156 aa)" FT /gene="SPAC227.13c" FT /gene="isu1" FT /product="similarity to iron-sulpher cluster proteins; FT Nif-u like protein; iron metabolism; mitochondrial" FT /protein_id="CAB61462.1" FT /translation="MSVFRRSVQCVGVLPSILAQRSSLLARPANLQFLKTNSSKFVPQV FT TANVSRRMYHKNVLDHYNNPRNVGTLPKGDPDVGIGLVGAPACGDVMRLAIRVNKDGVI FT EDVKFKTFGCGSAIASSSYVTTMVKGMTLEEASKIKNTQIAKELCLPPVKLHCSMLAED FT AIKSAVKHYRSKQLTPVGTTAGAIESATA" FT misc_feature complement(18489..18869) FT /note="Pfam match to entry PF01592 NifU_N, NifU-like N FT terminal domain," FT CDS join(21515..21715,21797..22303) FT /db_xref="GOA:Q9UTC5" FT /db_xref="SPTREMBL:Q9UTC5" FT /note="SPAC227.14, len:235, LOW SIMILARITY:Arabidopsis FT thaliana, AAD25806, f10o3.15 protein., (270 aa), fasta FT scores: opt: 273, E():7e-11, (30.5% identity in 243 aa)" FT /gene="SPAC227.14" FT /product="similarity to uridine kinase" FT /protein_id="CAB61463.1" FT /translation="MALQVDAPDVSSYDELYNRAVELLKHQQRVLIGLAGGPGSGKSTL FT CAILAKAWNERFGSEIVKIIPMDGFHYSLEELDRFDNPEKARALRGAEWTFDADLFYSL FT VRLMKKITDRELYAPSFDHAIGDPVVDDICVEPKNRILIFEGNYLLLNKPPWSDACKLY FT DIKAYLPVEHSVARARVAHRHLVSGLCATEEEAIERTDRNDMINLTFVEKNMVTPDIVL FT QQLRLKTVKTSSL" FT misc_feature 21716..21721 FT /note="gtaagt, splice donor sequence" FT misc_feature 21781..21796 FT /note="ctaacattttttaaag, splice branch and acceptor" FT CDS 23828..26449 FT /db_xref="SPTREMBL:Q9UTC4" FT /note="SPAC227.15, len:873 SIMILARITY: LOW to FT Saccharomysces cerevisiae, HEX2_YEAST, HEX2 PROTEIN, (1014 FT aa) fastsa scores, opt:400, E(): 1.6e-15, (23.8% identity FT in 621 aa overlap)" FT /gene="SPAC227.15" FT /product="putative regulatory subunit for protein FT phosphatase; similar to S. cerevisiae HEX2" FT /protein_id="CAB61464.1" FT /translation="MSNKPDANDQCMVKETISRMSMSKEKPFLRRNYSSPSFNDSVNSV FT NDEFQTYQLPNGEFSDNMNDLYFPFRKGNESLMTENSNYPISEQDTQHNHISDFPSRRM FT QLDGMNHSNNDTYSTAIPFSKDSSVFDAVGQQSSVPIHINPAYTNSHQNSYSLNETYLS FT YDFFDNHRGASSSAVSKDGLASPRPTKDVDADDTTWYFTSSPSFQPLKDSDRSQTKNTH FT EETSPIVSSPEDDADAAFKPSSLPSTSISASSNAFYKPAAPDNERPLDPHITPYLRLQL FT LTTGADDNDIRKNALTQVDYLSYDWKETDIWASWREITKTKANYDNGIRLENASWRTWM FT KHKFKLKTISPETLNWLKECDVTWLYGPLLHTSMPSRHHSHRKKEKEKEKSKAPRVTPL FT THKTNDDEANHSETSSGSSLAKKPILKRRTPQELLLSGRDLTPWPQIRRFDSLLARNRG FT DIFSNRNHATIRSALFSQRYPSHSKRHIHFNDRVQQCIAVDIDSLPSDSESASYNTDDA FT NSVVSPSKDGISTTTVSSDATRSSQSSHFRIIEDLPDSKLKYSLEDQATYDQSSRYPGR FT HFGKTGRSHFPRAPEYYGENDFEEDEVYRDDRHYENEHDEYDPNLIYYDNEPTEENRLV FT FEDTNNTFIDTDSDDSNADESQFLEYANDSPNSSESLESLNNQSYSSSPYSVFSHPPPY FT MGRQSLNDSPQTSDFKASNLNDSSSNVHSIFQTRETTSPSVQNKTPTKYHRELKSSKDG FT HEQASPLVSSSPSGSFTSQISPAATTTATNLDAVSLSPSTVRTGSQISDIGNDAISTTR FT KTVRAFLENANPYSTNNDGNPSNNTSDVEVNETSMNDNSEEPISSNWLVDLFQKSLKSF FT RE" FT snRNA 27308..27385 FT /evidence=EXPERIMENTAL FT /function="guide for 2'-O-ribose methylation of rRNA" FT /gene="Z8 snoRNA" FT /product="Z8 small nucleolar RNA" FT snRNA 27519..27618 FT /evidence=EXPERIMENTAL FT /function="guide for 2'-O-ribose methylation of rRNA" FT /gene="Z7 snoRNA" FT /product="Z7 small nucleolar RNA" FT snRNA 27773..27857 FT /evidence=EXPERIMENTAL FT /function="Guide for 2'-O-ribose methylation of rRNA" FT /gene="Z5 snoRNA" FT /product="Z5 small nucleolar RNA" FT snRNA 27969..28056 FT /evidence=EXPERIMENTAL FT /function="guide for 2'-O-ribose methylation of rRNA" FT /gene="z4 snoRNA" FT /product="Z4 small nucleolar RNA" FT snRNA 28206..28295 FT /evidence=EXPERIMENTAL FT /function="guide for 2'-O-ribose methylation of rRNA" FT /gene="Z3 snoRNA" FT /product="Z3 small nucleolar RNA" FT CDS join(complement(29255..29353),complement(29149..29207), FT complement(28908..29042),complement(28706..28851), FT complement(28585..28646)) FT /db_xref="SPTREMBL:Q9UTC3" FT /note="SPAC227.16c, len:158, SIMILARITY:Saccharomyces FT cerevisiae, Q12146, chromosome xv reading frame orf FT yol146w., (236 aa), fasta scores: opt: 120, E():0.11, FT (29.2% identity in 195 aa overlap)" FT /gene="SPAC227.16c" FT /product="hypothetical protein; similar to S. cerevisiae FT YOL146W" FT /protein_id="CAB61465.1" FT /translation="MDYYDIDSILSENQKVPCTSTVSIPGLGHEGRMVPTGSKVELPFW FT LAEVLAINSFVSIHMPAPFSSVVRNALKANPNSVSIRDITTHYYHFAEKMLHLISDDSL FT VQISLNTLRSRAMLIADASLNPQGALQQNSQFIEGLDDFEKHILRVSHNAHRSLINWQN FT STS" FT misc_feature complement(28647..28671) FT /note="ctaacaaaagctcgtgctgccacag, splice branch and FT acceptor" FT misc_feature complement(28700..28705) FT /note="gtatgt, splice donor" FT misc_feature complement(28852..28865) FT /note="ctaactcattgtag, splice branch and acceptor" FT misc_feature complement(28902..28907) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(29043..29054) FT /note="cttactttatag, splice branch and acceptor" FT misc_feature complement(29143..29148) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(29208..29228) FT /note="ttgactttctaaacagtttag, splice branch and acceptor" FT misc_feature complement(29249..29254) FT /note="gttagt, splice donor sequence" FT CDS complement(30383..30748) FT /db_xref="SPTREMBL:Q9UTC2" FT /note="SPAC227.17c, len:121" FT /gene="SPAC227.17c" FT /product="hypothetical protein; very low similarity to S. FT cerevisiae YDR512C; sequence orphan" FT /protein_id="CAB61466.1" FT /translation="MNNFKENDEKSTFGQYAELDKILDLKKGIPEDPCSLQYYFDQMAM FT CLTVFSQMNHYYRYGEYNRCKGNFKDFKWCLSTKSKAHEEAQEGLRKRRLQQWMKFRQG FT PNSEDIWKMRTSPKSSE" FT CDS 31104..32210 FT /db_xref="GOA:Q09694" FT /db_xref="SWISS-PROT:Q09694" FT /note="SPAC227.18, len:368" FT /gene="lys3" FT /gene="SPAC227.18" FT /product="saccharopine dehydrogenase" FT /protein_id="CAB61467.1" FT /translation="MVAPHLWLRAETKPLEERSALTPRTAKILADAGFQITIERSSQRA FT FKDKEFERLGFPMVPEGSWRHAPKDAYIIGLKELPENDNSPLKHTHIQFAHCYKNQEGW FT REVLSRFPAGNGLLYDLEFLQDDNGRRVAAFGYHAGFAGSAISCLVWAHQLLHPNKQFP FT AIRPFPNEKSLVRHVARQVRLALKKNNNQYPRILVIGALGRCGTGACDLASKIGIPFDN FT ILRWDINETKKGGPFTEITESDIFVNCIYLSMPIPKFCTVESLNVPNRKLRVVCDVSCD FT TTNPNNPIPIYNVNTTFDHPTVEVKGVTTPPPLEVISIDHLPTLLPRESSEAFSEALIP FT SLLALKDVDNAPVWVRAKKLYETMVQKL" FT misc_feature 32061..32799 FT /note="nominal overlap with cosmid SPAC2F7, EM:Z50142 S. FT pombe chromosome 1" XX SQ Sequence 32799 BP; 10728 A; 5834 C; 5860 G; 10377 T; 0 other; gatcccaaag tcggtggtaa aaaacgcgga ttgatgttca ggcaaaacgc gaactaccca 60 ggccattcgc aaaacaaaat caatcgcact tacaactgca aatgtgaatg ttgggaataa 120 acgccgaacc ccaaatttcc agttttggat tgataacggt tgcttaaaaa agggaagact 180 ccaatccatt gaaacatccc accaaaatga ataagttgaa tttatagctg aagaggtatt 240 ccataaaaac catagaaagc taaatctttt ctttgcaaaa atcccaagga atatcgctgg 300 aaaagcagtg aaatacttga tagaattcaa tgtactccaa aatttatctg atgaattatc 360 cgcagagctt ctttcaatca aacattgacg aaatcggata gcgtatggat acgctgcaat 420 cattgacata ataacctcat tttcatattg ttttctatga gagttattag gtgagtcagt 480 tacgtaaatc aagattgctc cagctagcca gagatcagca atgaccctcg agtaagaagt 540 caataaatca gaaaatataa catcgggaaa tttgtaatca ggtctgtagc ttcctcccaa 600 aatccttaga cactgtcgag taaacacctt tctctggaag aaccagaact tatgtacagg 660 cataaaaaca ataacaccaa aaataaaaac ggggacgtat gccaattcat cagacccaga 720 aatcaaatat aaggattcgg ctattacgaa aagtagagta cctaatatag atagggagaa 780 tgacaattgc catagaggag cattagcttg ctgtgatcga ttgacaggca acggagtatg 840 taataatgag aacacgtcga ccctatttat cactaataga tgtaatatca atgtgaaaga 900 ataaagacca aatacgacca agaagaataa tctcaatact agaggaaaat aattgataaa 960 gtgattcaaa tcctctatca acgccatatt aaataaaagg gagaaaatct gaaataatat 1020 attaaaataa acttgaatgc aattatacaa tggatgaatt tttacaaaga gagacgcaaa 1080 cagtgtaaaa tatgtcgagt caagttgtac agccgatctt ctaattatga tgataaaact 1140 tgactcataa ataatgaaaa ttatcaaata aagggttcta tgatgataga gattagcatt 1200 actgcttgaa tgtcgagagg tgcgttgtgg aaatgaatgc aatagggtac accaaggtaa 1260 aatcttaaat accaccacag ccaagaatca tgttggtctc tacaaagaat ggtgggattt 1320 tacagtaaaa cttaaaacat gaaaaagtaa ggtgaatttt taaatatatg acgaaacttg 1380 tgttatgctg aatattaata ttaagctgac aatgagtggt ttggtttagt agcatataga 1440 tgatgcgagt agagcaaatg ggttacgctt aaagtagtat aacagatttt gttgaatgga 1500 acatcaaacg aatcaggtta gaaaatgatc gtagataaat ttgatggctc aatcatctga 1560 taaccgttca cacctcaatt tactaattat gcttgaactc cttaaaaaag tcttgaagtt 1620 gattcacaat cctttaataa tacagattga cggttttcga aaaatggaga gcaaatgctt 1680 attcattact ttaaaaattt atcggcgcat agcgcttgga gaatgccgaa aatatttgag 1740 tccaagccaa ttaaagaata accatacgaa aaaaaccact gtacaagtca gaattaatat 1800 acatggataa taagaacgaa taggtgaaac ctgttaaaaa tattagaacc aaatttgtac 1860 aagatagaga aattaaaaca tattggtaca atgaccctgg cagaaaatat tcgacgatgc 1920 cattgagatt ttagcatcat aacttacatc gccatcaaca taaagtggta tctcaacaaa 1980 gttaaatata gtcataagtc caaatacaaa taaaaaccaa caggtaaata gcagtaagta 2040 tccattagat accatcgaac ccatcatttt aaccgtattg ataggtatct tcaggcacgt 2100 tttaaacaaa atatgatgag tagtaattta attataacca acgaaaccta actaaatacc 2160 ttttataaag aatctatact agttgtacaa gagcaaacgt ttcgcagaga caacaaagta 2220 aaagtacaga atctcctcaa atgttaaaga aaaaaggaga attaaaagaa aaacattaaa 2280 agaaagcctt aaaaaaccgt gttaaactag atctgggata gtattgccct attttgaaag 2340 ttttcccgtt actgggattt tatgaggtca aggaagctcg cctttgagag ctctttgact 2400 ttttgctcac gagcagtacg accaccagag atgttttctc tatttaaaga gctttgaagt 2460 tgagcagtac gaacagcatt gaataattga actacacctc tgcgagcaat acggcgaagc 2520 tcacgttcat gggtgaataa agcttttgct gtttcagcgt taactgcaac aacgctcgta 2580 acacgaccaa ccatctcttt tctcaatctt tcacgtcttc tagaagtacg tagtttagag 2640 tctttttttt ccgcattact ttttcgtaaa gcttttttag attttttaga caaacttaga 2700 accggcgtgt cttgttcatc agtttgagta acttgttgat ttaagatatc agcaatgtca 2760 tcagcaatgg tactttcttg aacttcttct tcaatttcat cttcagaact attggattga 2820 taaaattcgt cttcgctgtt caagtcttcc aactcttcct cagagttttc gctatcatct 2880 tttacaaatt ttttagagga atcatcttct tgagagacaa atgatatatc ttcgtttttt 2940 atttgagatc tttgtgattt cgccattaat gtgttgttgt ctaaatttga aattttttga 3000 ctggaaccac caagtaaagc atggtctcca aaaaatgcac aatatcaatt tgaagcgcct 3060 agttcgttct aatagaataa aactgatatt ctgtttcttt aattatataa aaaaaattta 3120 attttatttt aggtagttta gttcaatttg gcgaacacta aaatattata aatttgctca 3180 gtataatagg aatgggaata attggaaatt tctgaccaaa aaaacactaa taaagctcaa 3240 agcttgatac gttcatgctt atgaccacga acaggggcta ctcgtattaa agtaaaataa 3300 actagaatgg gtttcatcca gtctcaaaat agggctgggc tggtaacaca agaaacaaat 3360 gcttaataaa aggtaattat taaataaata ttgatgagag ggggtaagaa taagaattag 3420 gaaaacctaa cagctgtgag acagtaataa ttaatattag aaatcatgca cacatctcaa 3480 ggaaactgat taaccttgga ttgtcgttaa aaaaataaag actttgatcg ttttcttgag 3540 tatatacaca acggataaat tagttcagcc atttgcgaac aatttcgaaa ctgaggaagg 3600 taaccgaact ggcaggtatg gtgcgtataa aatttgttgc catgccagag taatattttc 3660 tccaaccctc tgaacgccat atgtctcgaa taagtaaggt agccgagttg tgtgtaggtg 3720 catccaaact ctgcaaccga gttctcaaaa cttcatgagg ataagtgacg gtagaagctg 3780 cgattttaga caaagtagct gctaacacta tatgaaagtt gcttttttta ccaaaaaaat 3840 catccaaaaa tgatttaaaa tattcgtaca gtggaaattg gatgccaaca tgcaatgtac 3900 caaataaaga ggggaaaaga cctcggtaaa atgctgcaag gccttcgtat ttataaattt 3960 ttcgaaatgc gtcaaatgtg ttgttgtatg caggtgaaca tgcagggcct gtgggaggat 4020 tcactggatg ctgtgatgga gaagatttga cattcgtcct acgcttgagc caaaagcgag 4080 gcattctcca tttgacggat ggtgcgtccg tttgaagatt acgaaactgg acggttgtag 4140 ccgcagcaat tttatctaca aaagaagaag ccctaggatg tgattgagtg actaaccttg 4200 tttttacaac ccaaatgggg ttagtaagag tgacacttgc agcaccggcg ataaccgcag 4260 aaaagatttg accaccccag taacgataaa attgtttgtc agaactatct aaggaagcct 4320 tgatgccaac cttggacgaa tcaatttcgt ggagagaagt gtatttttta tttaccccaa 4380 atagcacttt gcatttttca tagactacaa aataaatgga ccaactagga agataaccta 4440 acatcatggg tccaacacct ctataaagac cggcgatgcc ttcattgtga aaaattgttc 4500 gcatcgaact gagggtccca cccaaaacca ttgtattttt tccaccacca gttgaataaa 4560 aagccttttg tgcctgcttt cttgttttta ctacatctaa aggtgccact acaagagaag 4620 aggccaatcc agcagctcct cctgctatag catcctttag agaatcatca accataaaga 4680 cggatcaatt tcctgatgat aatgcatgca tctaaagaaa acagcaatta aataatagac 4740 cttgacaaat tctttacttt tttagacgct gataagaacg atccaacgcc ttacgatgtt 4800 tcaaattgga aatgtatata tattttagcg ttgatgtaag aagctgtaca acaacatata 4860 tgtaagtaaa gtgtttggca gccgtcaata agaaagtcga atcactgtgc ggtaaaccac 4920 attaacgaca tgaatgtctc cgaattacta attgagagga cgttccatgc ccttaaaaga 4980 gaatttcttt tatatgtgca tatcagatat gattaaagtc gtaatgccca ttaacaatat 5040 ataatggtga cattgatgtt gctaacagct ttacacacat atctcaattt tacttcacag 5100 atcagttggc tttataagca ccattggaac agtgcttttg cttttgcttt tgctcgtata 5160 agtattaaga ggaaattact aatataaaac cttagttttt catttttttc caagtccaaa 5220 catattgttt ttatacatta gcttctcttg attaccgcca atttctagtc gaaaaaatta 5280 tttttttaag aaatcctaca tttgctgaga agaaatgttg aaaacgtagt aactacacag 5340 tgtaccacta tattgttgga taactttgta aactccaacg tactgttttg tcatactctt 5400 attgtcaact ttagaagcaa gatgtagaat taatatactt gtaaataact gaaacaccat 5460 ttttgtcgag acttaacttc aaatatattg acaggtgatt gcctctattg ccctcattgg 5520 aatagtgcgt tgaacaatca gactgtagcc aggcttatgg gacaataatt ccttcttcaa 5580 ttacttattg ctttagcaaa gataaagtga ttaaattggc taaccgtgac aataatgagc 5640 tttaagtctc aattacttat ccttgctcag aagctgtcga aaggtggtat ttcttgtgag 5700 ttgattgagt ttgatgagtg tattttgaag ttagaatggc atactgagct acttgataaa 5760 aatgattcct tattatacga gcaggaagaa gatgatattt taagccttat gaatccaatg 5820 atcactatgc acgcctggat tagggattct ccatccttcg aagtcccgca gttcttcttt 5880 caaccttatg caaacggatc agatcctctt accaagatgg aacagatttt tgagttatta 5940 gaaggatcca gtcaaaattt agcatatgac gctcttgcta ttggggactg tccaggtaca 6000 gtaggcatag catggtatat ccatccatgt cgtacgcgtg attatttcga aatgcttcag 6060 atagacaaag aggatcccaa gtatctctct ctttggttgc tatatattca tcaagtcctt 6120 tctccgctaa ctcagcctat aataaaagca gttgacgatg ccgaaaaatc ctaaagataa 6180 cctgttataa acgggtatgc ttgctaagac tttgtcttat taaatattat tccccatgat 6240 taaaactaaa ttaaaagtca atttaatccg tattctctgg ttttagttta taataccctg 6300 tgaatctata gtaaaatttt gacctgttat ttgacagcaa aaacattacg gatctgaaga 6360 cctcaattgt agaaaatagc ttttgttctt taaatttgta gataaaatac tatactaatt 6420 aataatcctt ctgttttgac atatcattca actgttccac ttaaacctct acttgaccgc 6480 attgatctct acaccaacaa ttgtttgtta agacaaacga aaccgggtta tatactattc 6540 ctcctaacac accttagcaa caaatatgga acaagttcct gttctagcag aagatcaaag 6600 gaatttaaat gaattttcag tgttgcattc tcgaaaggcc attcaagaac ttgatattaa 6660 gaatttaaaa acgcaaatag aggatattgt tgacgctaaa aatgaatgtg aattactaga 6720 cgaggatgat ggagacgata ttccagcttt aaaggttggc gatgcctttt tccaagtttc 6780 ccttcctgta ctccttgacc agcttgagca gtcagaagaa agtttggaaa agcaagtcga 6840 cgtattaaga tcttccatgg aaaaagacga aacccgcatt caagagttga aatcaatgct 6900 gtactctaaa tttcacgatc aaattaacct agactaagat ttggaaaaag cagcaaatct 6960 caaaattaga agcttcatct tatttttctg aattagtttc tttaattaaa taacatttca 7020 tgcatttaaa tttattcaca ataccaaatc tgtatgcaat tagcgcctcc aataagtaaa 7080 cttctttgtt caccctaagc cattacaagt atccaaccac cactatggca catgagattg 7140 aaattgactc ggaagctgac ctaggtcgta caacatttga ggctgaagac ctttataagc 7200 agagaactcc cattacaaag cctccggccc ctagattaca atctcgtcgc gcatccatgc 7260 aagagacgcc atggaccatc aaagattcat ttaacgtgga aactaaagat gtggttcaac 7320 gatgtataca tactcttatt cccactgtaa atttctttga tgttgtagat gatcgtcccg 7380 atttatacgg tcctttttgg ataaccacta cggttataca ggctctattc ttttccaact 7440 caattaccga atacgctcgt tatgccacag ggcatggtac aagtggctat tctataaaaa 7500 agttgatctc tgcagcatca attatttatg gttacactac cattatcgcc gttttgttat 7560 ggggtatcct agtgtggaac aaatgcaacc ctaagttact cgactgtctg tgtttatatg 7620 gatatgctaa cattgtttgg cttcccgttt ctttagcaac tcctccgttt ggattgctat 7680 ctactttggc ctcccatatt gtcaaatatg tacttacagg gattggtttg ttaatttcca 7740 ttgtgttttt aactagaaat ttatatccta tctgtcagca agccggatca aatttgtgca 7800 aacttttatt gttcggaatt atcgtctttc actgtttgct cgctttgtct cttcaactca 7860 tattcttcag ttaatatcct aatttgtgag gagtttcttt tatcagtcgc attgcttcat 7920 tcgaaaatta tactattccc cttctttcat tctttagaaa agtcattcag catttaagat 7980 cctattgagt ctaagtgttg gtatactcta tatgattcag tttatacata tattcgcttt 8040 acatttgatt ttctactctt tttactatag ctactaatgt tccctcaatt tactaggttt 8100 ttttttcagg tgcaaaatac gtataaataa tcatttctta tgcattgatg aatcatgcct 8160 tagtaaaaat aattgtagcc tttttagtga accaaagact ttatgacatt tagtcatatt 8220 tttgcaatcg atctcccgtc atttatatag aaaacttaac acattattac tcgttgttca 8280 acaaaaaaga gctgaaggta aattaatggt gaagcttaac ctgaaaagta cttttacgat 8340 ttcaaattca gatttttttc aacaagagaa aaaaactttg tgagatattg aaaaaacgtt 8400 gaaatttacg atgcatcacc acaatttcaa gattaaaaag gaacacgtaa aaagagaaaa 8460 agaaaaatac tgtggatagc aaagtacata tgtatcgatt cacggcatac atgaagggag 8520 ataaacaaag caccctttta tcattagtcc taaaaacttt atttctgtca ttaatggtta 8580 aaatggtgtg tgtatataag aatacaatct gaaagaagaa ggtaagaaaa ctcttattcc 8640 cggaagttca ataaaaaagg aactatgttc agtctatccg tagatcataa aaacaaacca 8700 aactccacat aaggacatta gagcttagag aaaacaaaaa gctattgaaa cattagtaaa 8760 caaaaagttg ataagcaaac gtacattatt agtagcggcg atggcaactg agtcttcaaa 8820 gggatgccaa ctggcatgta atatcttctt attgtaatcc aggttatcag gatcaaggcc 8880 aacagaagca gatcccatcg cagcttgagg ttgtgaccgc caatcattat ttttcacagc 8940 attcaacttt ggaacgttat ttgcagcaga ttttctggct ctaaatgcag ccttgtcggc 9000 ttgcaaaact atctgtcctc tatcgccagg caaagaacta tctgtggggt aaatcccaaa 9060 gttgttgcta taacttcctg ataaaacgtg tttgtcgtca ccagaaaagg tacactcgaa 9120 tttatcaaaa atacagtcat tttcatagag atcgcataac tttgatcgca aaacatcatg 9180 caatggaata gttttaacgg gagctttttc catgttgaca tcccatatct taagagttaa 9240 ataatctctt gaaagaatat agcggccatt ttgtgagaac ttaacgtctg aaatgctaga 9300 gatgatttca gaaaagaaac tcttggaatc ttgatcttct tgatcctcga aaagcttaca 9360 tggattatcg cagagcgcag attgacgcaa atctaagagt ttgatatttc ccttgctgct 9420 actatacatg agatgattgc agtttatcgg gtgaaactcg gcactagtaa taacttccgt 9480 aagttcttcc atattttcag gtttaatgtc aactatgttg aatgaatgat cggagatgga 9540 caagttccat aagttgatac gtaaatcatc agcggaaatg taagtttctg catcagagtt 9600 aacgctaatc gaattaatat gatatgcgtg tgcattagcg taaacacgtc gtggatatgc 9660 agcgataatc atgtcatgat ggttgagtcg tgggagtcga agttgcgaag gtgttgtcaa 9720 aggtccttgc ataggactgt ggaaactgtc cgacaaatta ttttcggcaa cgactttcaa 9780 attcttttca tatagtttcc acaattttat agttttatca ttcgttgaga gtaaaaaatg 9840 cgctcgatta gtcctcttgc accagcgaat tttattgatc ttttcttcga tttctaagga 9900 cttgagataa tcaaactcgg gttcatgact ttgaaattca gtaaaaaact tatactcaca 9960 accctttttc gaatgatttc gctcaaaaag aacgactctg ccacctttat cgccggttgc 10020 tagataatca cctgtgtggt cgaattctac tgctgaaatg atatcggcta aacttgttag 10080 tcatttattc agtgattaaa gtaaaagaga actcttttat gagagaacta ctcaaaacca 10140 ataccttcag tgatgtcttc cacatcaccc ttgtcaccaa agcatctaaa gagttagtca 10200 ttaatttttt tcacacatcg tttacatact gggcaaattt ccactgatcc aaagagtctt 10260 ctatatcatc catcttctac tcgtattata ttaagatttc gttcccgttg gtacactttg 10320 ccaatttcaa ttgtatacga agatcttgat cttcaaattt ctaagggtat ctctataccg 10380 tctttggatc ttttttcaaa agttttgata caaagtttcc cagttttcac tggctttttt 10440 ggagggctgc tgattttcct aacttgatgg ttcgtatcaa atgctgctac cctaacgaat 10500 ctacaccact cttcggcgag tcaaaagctc agtaaaattt ttatcggtaa atcaagcctt 10560 aagcgacttt aagttattaa tggatttttg ataaatacaa cactatttca ttacttcagt 10620 gttcatctta cgctttacta cacataggat tttttgctca actttacaaa gtccagtgta 10680 aaacttgttg gcaatttccc attaatgaaa ccttaatcat ttgtacgcta aagaaaggtg 10740 tttttgatta taaaaaacta gaagttcatt gtcatataaa agatccatat tgtttttata 10800 gtttgcaaaa ttgaatacag cagataagta aattacaaaa aaataagaaa cataactgga 10860 aagtagcaaa tattttacga ataacgtatg aatgattaaa tgaataaacc gtccttgata 10920 cattacgatg gcgctctacg taagcgtttt acatactggt aaacgatact taagttccta 10980 aattttcttt tccttctatg ttgcaaaaaa catatgtaaa agggagactt attatttaaa 11040 acttattttt cggtttctaa atacttctat tatcccgatt atgtgtcgat ttggttcgcc 11100 gcaaccaaga caaacccaac gtcgataatt aattttattc cataaaaaaa aatctcaata 11160 atcaatgtac ggcatcacta attgcatata ctccattgat aacttgattt cattacctaa 11220 tatacagtga cacattaaaa aacgcatcct ttaccagtct ttccgctttt gaggaggatg 11280 cggaggttca gagtgtttag gactagaaca tgttagtaat agaaagagaa agtcaacact 11340 ataattcttc aaaaaactta ctgagcatct gggcaattag ggcctagcgg acaaaaccca 11400 gctaaatatt ttgggcaagg ccttggtttt cgtacatgtt tgcctcgaca tataggtcct 11460 aaaggacaaa atcccatatt ataccaggca cagacaccaa cttgtttact gggatccaaa 11520 tggagatata aacactcttc gccattagaa caccagccgc gctctgcata aaagtgacat 11580 ggaggcatct tttttaaatt gtactcgtgt aaaaaatcac actgttcacc ttttttacaa 11640 agtccacgaa gccttatata atattagtta tcatgaaggt agaaacaaaa acaaatagaa 11700 aaatacatga aatatatatt catattactc ttctttatat atacatacca atgcttgcaa 11760 accacgctac ccattttcga tccagaatcg cgtccatttc cagagtttag caaggcagac 11820 cttccgaaat taaaattttg ctttaaatag ttatcaaaac gaaattgaac tgaagaaaaa 11880 tcagctgcta tagctttatc tttgatataa tcagtcattt tgtagtaacc agtagatggc 11940 ggaggcaacg ttgttcagtt gacttgaata tcacaaatac tttattgact ggcattcaca 12000 tactataaat gatgcttatt aaactagaac gaattaaatt attcttataa tattcatgaa 12060 atcgctattg ttttaaggtt ttcttcatag gtatgtttga aacctaagta aagaatgata 12120 ttatgcagca tacgaataaa ataactttta taaaacatat tctttttatc taaaatttac 12180 ctcgtcagag acataactaa ttgcttctgt tgagaatttt actaacatac taatttgcaa 12240 cagaaaacgt attatcttcg cttccacatg caaaacatat tcacatgacc aagtactttt 12300 aaagttttta cgagcttata aaggtaaaga atcattattt tttaataata cagcattaaa 12360 attcctcctt tactatcgct cacgtaggat gcctattcag ctaggtcttc agcgtatgct 12420 acagctcttg aagcaccttg gcaatccaca ggaatcgttt tgtgctgtac aaattgctgg 12480 gactaatggt aaaggtagca tttgtagcta tatatacacg agtcttttgc aagctgctat 12540 taaaacagga cgctatacaa gtcctcattt cttagagcca agagatacca taagcataaa 12600 tggtcagatt gctagtgaag agatatttaa tacttgttgg aagcaggtga ttgaagtgga 12660 tagaagattt cgtacaaaag cgacggaatt tgaattgtta actgctactg cgttccaatg 12720 ttttcatcat tcaggtgttc gtgtggctgt aattgaaaca ggaatgggtg gtcgtttgga 12780 tgctactaat gtatttgaag aaccagttct ttcaataatt tcacgtattt gcttggacca 12840 tcaagcattt ttaggaaata ccttagaggc tattgctaaa gaaaaggctg ggatctttaa 12900 aaagaatgtt ccgtgcgtgg ttgatgggtt aaatgaagtt aacgtcctaa atcaattaaa 12960 attaagtgca gaggaaacga gggcacatcc gttttatttg gcaaaaggaa aatcaggtga 13020 aaacaaaaat gagtggatca tcaatactcc aaattgggga accaatactt ttagtactcc 13080 attgaagggg gattatcaag gacaaaattt ggcttgtgca gtaactgctc tcgatatcct 13140 ttcttcgtca ttttcaatta tgcttcccca tgtacaaaat ggtgtaaaaa atacatcttg 13200 gcctggaagg cttgacattc gttcggttcc ttctttgggt gatattttat ttgacggagc 13260 acacaataaa gaagctgcga ttgagcttgc gaaatttgta aattcgcaaa gacgtgagca 13320 caataaatca gtatcatggg tagtagcttt cactaacaca aaagacgtta ctgggattat 13380 gaaaatcctt cttcgtaaag gagataccgt tatagcgaca aatttttctt cagtaagtgg 13440 gatgccctgg attaaatcaa tggaacctga agttataaaa aacagtatat cttcggaatc 13500 ttctgtggaa tgctatactg cagataatct aacaataagc gaaattttaa gactggcaaa 13560 agagaagaat tccagcgtaa ttgtatgcgg tagtctttat cttctaggag acatgtatcg 13620 ttatttaaaa ctggacgtat agcctctaaa tcgtgctgtt tactttcata cgtttttcct 13680 tgtttgacaa atttatcata tgaattgtca cagagtgatg aattgtgctc tagagaattt 13740 tgttccatga cttaaaaact aaaatttact ttcaaagaag cttgaatgat gctatcaggt 13800 taatagaaaa aagataaaag atttatatta agctttgatg ggtttttggt gtgagttaag 13860 atattgagtt agaaattgac ttatagatta cgaatacatt agtttaaata cttggtgcgc 13920 tctgcctgca gccttaataa aacagatatt attttcatta tgtgactaga tcttgattta 13980 caattcttac aagataaggt gggataactg aagcatattt agcacattga aagattccgc 14040 ctttctttta attattatta aatactgtcg taactgcaat aaaataagta aaacgctgaa 14100 atcgttaaaa aaatataccc ttctatctca caggttgagc taatcaagtt gatatacgta 14160 tagtgcaaat gataggcatt taaaaattag actaatatag tttaactatt acattaattt 14220 taaaatacac aaacatttaa ttactgtttt aaaattatac tcagagtcta attaattaca 14280 gatttaccgt aatccatagc gcttgttatc tatcattaca gcaacaatga ttgctacgca 14340 ctaaaattcg tatacgtttt agatataaca tgtataatcc accaacattt tttgagtata 14400 caaaaaagca gaatggctga acaaccttct cggcagcaga gtatgtactg tggatgagtt 14460 taaaatacaa aatagttgac cagttccagt tctacagacg cagtacaatt catataagtc 14520 tcggttacaa caaattgcgc agaagattgt cgatttggaa accgatgctg acgaacataa 14580 gtatgtgata cataaaaaat ttttaaatta aatacctaac taaaaagact tgttatggac 14640 acattaaact ccatggataa taatcgacgt tgttttcgaa tgatccatgg agtgctagtg 14700 gagagaacgg tgggaactgt tgtgcctatc cttaaaacta ctcaagaagg ggtaaggaat 14760 ttttttattt tgacccttta ttgtcagatg aatttttggt cttgatgtac taatcaaaat 14820 attagattca aacagccatg aatggtttgc tcgaccagta taagcagctc gaagcagaat 14880 tccaaaagtt tcaaaaagac aataaaattc aagtcgttag acaataatac agatgactcc 14940 attaattgcg cagttgcgtt cattgacacg ccgactgttt ttcaagtgct ttatcttcgg 15000 tttaacattt ttttcctaaa cagaggaaca gggatagaat ccaagagtat ttgtgtcatc 15060 aaatatcatc actttatgtt attagagttt cacttaaacc gtagacttaa tacatgtagt 15120 aagttaggta gaactaactt gattgcgtct ctacctcctt cacctcaggc ggagatgttt 15180 gagcaacttc atcaacaacg tgctgggaat ccttatggtc gacttcgttt gatttttctt 15240 taattacatt atagcacaca attttttcag agggtatgtc ctcttgaatt ttgaaagcag 15300 gtaatgagca taaaccggga acgtgaatag tcattgaata tgcacagctt gaaacttctt 15360 gatattgagt aatttcagga gtatccgaat ttgtactgca ttcataactt agaattacgt 15420 gtcttggtct cttagtaatg tcgcacatag tcccatttcg gaaagttgtt tgcaaatatg 15480 ctttaccttc aacaaatcca atagcccaat tttcttccaa attcttttta gtttgagtgt 15540 taggtgccgt accaagtata tacatagggt tagcaaggac tttgtcagaa ccttgctgcg 15600 gctccaaatg atattgacgc acgtgttgac cgtagacata gtcataagtc caataaccac 15660 gattctaata caatgattag cttgaaaaac actacatgta ctaaaagtag tcattaattc 15720 taaaattttt atggacatgt caaataatga ccttttagta aagttggttt gtttaagaca 15780 aataaaacaa ttagaactcg tacctcgatt aaaaatacat tagcaagctc attgattttt 15840 tcagtccctt gtatccgcaa ttcttgtaaa tcatagcttg gttcggttgt gctattttgt 15900 tttataagag acgcattggg atatacacaa aaatattcat gctttccagc atagaataat 15960 gacgataatt tagttttttc agttttttct ttaattgagt caatgtcgcc ctctaatatt 16020 gacacattac tccattcaaa cgaatattta ggatattcat atgcctacaa aggaagtccg 16080 ttagaattga agagaaatta ggttcaagag catacatcat tccagtctaa caaagaagct 16140 aaacatattg gaaaaataaa aaaccccaca aaagcaaatg gtagcaccat agtcctaact 16200 ttagatgagc cgattgcagg tagaatcaaa tgtggaaaca tacttgaact gaacatatgc 16260 gttatatcac agtataccga agtgcgcaaa gctcgaacaa tttacaaaaa gctaaatacg 16320 atagtgcgta aaaaatagta gtttacatta gaggtaagtg ttacacgaga ttgttaacat 16380 gaatgaaaac gagggcattt cacttggtga attaggtacg ttgctactag aagcattaac 16440 tcctcctttt aaattttaaa ctaataaaaa actttagaaa caagaccgtt ttcagaaggg 16500 ataacgcggt ttacaaaaga acaagcagct tattacgcgg agcaaaagga aaaggatcgc 16560 attaaggctc ttaaaattcc ttatgaagat tccaaagttc gtgaatatct gcgtcgttat 16620 ggtgaaccca taacttattt tggtgaagat gccttagccc gacgccaaag gcttcagcaa 16680 ttaatgatcg aaaagtccct agaaggagac aatccattag atgtagacca aggggcttct 16740 gaaaatattg agaaggagac gtatgttcaa ggaagtcacg aactattagt tgctcgtaaa 16800 aaaatagctc tttactcctt ggaaaaggca aagctcagat taaaaaaaga acgggaaatt 16860 tccgagattc cagtacctga aattgtactt tccggaaagt cttcaatcga acatttacaa 16920 aaggctgaat tgatgggctc tcagataggt ggtgagcgac caatagccat tgttagattc 16980 agtaataatg gaaatcattt tgctagcgga agctggggtg gccaggtcaa ggtgtggaat 17040 tctgataacc tctcagaggt tcaattgttt cgcggccata ccgaccgagt ttctggtttg 17100 gattggtatc ctctatgtca ggcatgggat gcagattctg agcagctgac tttagcgact 17160 ggagccgcag acaatactgt ttgtttgtgg aaagcaagtc aatctactcc actgttacgt 17220 ttggaaggac atttggctcg tgttggtcga gttgcttttc atccaagtgg tgattactta 17280 gtttctgcct cattcgacac tacatggcgg ttatgggatg tacatacagg cgttgagttg 17340 cttatgcaag aaggtcattc ggaagggatt ttttcaatcg cctgtcagcc agatgggtcg 17400 ttagttagct caggtggtaa tgatgctatc ggtcggattt gggatcttcg atcaggcaaa 17460 tcaataatgg tattagatga acatattcgt caaattgtcg cgatggcttg gagtccaaac 17520 ggctaccaac ttgcaacttc ttcagccgat gatactgtga aaatatggga cttgcggaaa 17580 gtgtcattgg cacatactat tcccgcacat tcttctcttg tttcagacgt tcgttatatt 17640 gaatcaggtg ttaacagatt catcgctacg agtggttatg atggctgcgt aaagctttgg 17700 aacccgttga actgctcatt gattaaaagt atggtgggac acgaagaaaa ggttatgagt 17760 gttgacggtt acggagacag atttatctca tcaggatacg atcgtacaat caagttatgg 17820 tacccttaaa tttgggtgtg gcaaacggtt ttggtaatga gtttaatata ggcaagacag 17880 tcctttctga ctatttgcgt gatgggcaac gaaacaatga atatatatga acatttatat 17940 tacatggttt aatagctaga agatgatatt catgtatact actaaagttt aagcaaacac 18000 agaaacagct tatagtttag aaataaaaga ctctaaatta tttttcatta gacgtataaa 18060 gattcgaata aaatgctata gcaggaacta aaaaaaaagg aaggggaaaa tgtacagagt 18120 aatgattttt ataaccacaa taacaagcaa ataagcatca gcagcatttt gaaagaaagc 18180 acttgcatca atttagtcca gatacatata gtgcagaaac attaatcaat atatattgct 18240 aaatgggagg aagaatgcaa gcaaacacat agaccatatg tttacgccaa agtcgacaag 18300 caatcttatg tggaaaacac tgtttacatg tacgcagttt aggaattaaa aggaccgggt 18360 agaaaattag gaggcggggt caaaaagcgg agcggaaatt agcagatttt taaacagatg 18420 aaagctatga ctttacaatc aagtttctaa gcggtagcag actcaatagc gccagcagtt 18480 gtaccaacag gcgttaattg tttagagcga taatgcttta cagcgctttt aatggcatcc 18540 tcggcaagca tggagcaatg aagttttaca ggaggcaagc aaagctcttt ggcaatttgg 18600 gtgtttttaa ttttagaagc ctcctcaagg gtcatgccct tgaccatagt ggtaacgtag 18660 gatgacgagg caattgcact accacaacca aaggtcttga actttacgtc ctcaataaca 18720 ccatccttat tgacacgaat agcaaggcgc ataacatcgc cacaggcggg agcacctacc 18780 aagccgatac ccacatcggg atcacctttg ggcaaagtac ccacattccg aggattgttg 18840 taatggtcta aaacattctt atggtacata cgacgagaga cgtttgcggt gacttgaggg 18900 acgaattttg acgagttcgt tttgagaaac tgtaaattcg ctggacgggc aagaagagaa 18960 gagcgttgag ccaaaattga aggcaaaacg ccaacgcatt gaacggagcg acggaagaca 19020 ctcattttag ggaaaacaaa agaaaaaaga aaaaaatcag atgacaaatc acgtcaagat 19080 ctaacaaaat atctgtatca caaatccaac tagatttgtt ttcaaaacgt atcaagtaaa 19140 aggcttgagt acgttttcag tgtttttggg ggatggcagg gagttttcaa agtttcagat 19200 tttatctgat ctatataaaa aaaaataaca gctttgcctt taaatctcct tatacgtaaa 19260 tgacgttaaa aagtgtgtaa gggtaacgca aggaaatttg taaaccgggt taataagatg 19320 acaataacta tgtacactcg atgaaaggaa aaatcgattc aactatgtat cgacaataaa 19380 caatcaagac gtggttgaaa aaaatcgtgt cagagttatg tagtcttata gcacacaaaa 19440 cgaattgctt tattcaatga aattattttt caaaacaact ttaaatttat gttcaaaacg 19500 tccaatatta aatgttggtg agttgtatga gtcagtagtg tttgagagca gtgcctgcta 19560 tatatagtgc aagtcagtct tgagtgtttt cggccatctt tatctcatct gatatgagaa 19620 gaaattctgt ttgtcgaaaa tgtgactgtt tttccctaac aaatcacaaa gctagcttaa 19680 ggtggatggt agcgaataaa atagggaagg caatagtggc aagcgaatcg gaaatgcggt 19740 ttcagcagta aacgccaatt aagggactaa aacgtaatcc ggtattacta gatttacgaa 19800 gaaaaagttt tggggaggcc acaacaaagc agtctgaagc ttatgcaagt atgatgtaca 19860 gctagacaaa taaagttgtt ttccatacac aatatggaaa ttccagtgtt cgatggtgaa 19920 ggatatgtgt tcacagtata ttcgaaacaa ggttgtggga tgtgggatat ggaaattgga 19980 aagaagatgc cgtccccctt taactgagga aggaatatca gatagcaggc aagaagtagt 20040 tagcgagaaa gaaagtagtc agttagggag tacaggtgga agggacggca tgagacagac 20100 ggcagagaac gggtagggtg cttgtatgtt taacaaaaat gatgatgaaa agttggtgga 20160 tgcacgacta gaagctggga tacatgcttg aacggttttt tggtttccat ttgtttatct 20220 gttttgcatt tatttcgata tgtaattagt tgctggtttg gattatacat gtaaataaaa 20280 aaggtgtaag gataatcttt caaaaagaga agtttgtata agaaatggtt aagccgtttt 20340 tatttttttt atttttttta atgcacctct tgcactgcgt atgttttttt gcaacaatcg 20400 atcccgataa cattgccaag gccgctaacc tacgatcata ctttccaata ggcaagagcg 20460 agtccatagt tgctggaact agggttccgc atcacggaat aacggagctg ggcgaaaaaa 20520 aaaggaacag gttgcaaaaa ggcactatac atttgatgtg taacaaagta atattcgaaa 20580 cagtctattt caccaataac agtttagcgg tctaacggtt tttttaaagg atgactagtt 20640 ttttacagca ttcagtaaat tagcgatata acattactgc gcccgtcatc cttaattaag 20700 ataggaaggc cgttggagat tgcaataaag taatgggcct ccaagcaatt gaggagtgtg 20760 ataaatatga gaaattataa ctatttttta aattttgttt ttattattta atgtaaatat 20820 cggtatttcg aaattgaatc agtggtatct gagacttctc ttaattttat atctcacatg 20880 ctccacaagt gtcttggagt gtatagcaac agaactcaag aacgttgaat gtaacgtagt 20940 gcaatgctat tcattcaaat tggtaaattt ttgattgtgc atattaacgt tacattgcaa 21000 tatatgttga ggatgctgaa gttgtattgc attttttaaa aataacagac tcctacggat 21060 ttatcctttg ctgcgctata atttagtagc ttagaaatcg ttctatccag cttgtaaagc 21120 gaagcaaacg caactttgcg tattgtgcga attggactca tgcttggaat ttcgaaactt 21180 aaaagggatt cggctttgag catgagatcc ccacacttgt cttctctcca tcaaaagtta 21240 ttgtgaattt atcttcaaat cgggaattaa tcatttgtaa gtgagtgttt acctttacaa 21300 cgtactggta aacagaagat caattataat aaacatctag tttggtatga gagatatttg 21360 atgctaatcg tgttatcata gattagctgt ataattgaaa tttattgttt tttttttctt 21420 ttaattccct ctcttttatt gcaaaactca tatttaactt tattgtttga ttatttcatc 21480 ccttacgcta ctcattcatc tgctgtatga taaaatggct ttacaagtag atgccccaga 21540 tgtatcgtct tatgacgaac tttacaaccg tgcagttgaa ttgttgaagc accagcaacg 21600 agttctaatc ggtttggctg gaggtcctgg ttcaggcaag tcaacattat gtgctattct 21660 cgcaaaggca tggaatgaaa gatttggatc ggagatcgta aaaataattc caatggtaag 21720 tttttctgtt actatgcgaa atggaaatga aatgataata cgattttttt gtgattctgg 21780 ctaacatttt ttaaaggatg gctttcatta ttcgttggaa gagcttgatc gattcgacaa 21840 cccagaaaag gcccgggctc ttcgtggagc agaatggacg tttgatgcag acttattcta 21900 ctccttagtt cggcttatga aaaagatcac tgacagagag ctctatgccc cttcatttga 21960 tcatgcaatt ggtgaccctg tagtcgacga tatttgcgtt gagcccaaaa atcgaatttt 22020 aatttttgaa ggtaattacc ttttgctcaa caaacctcca tggtcagacg catgcaaatt 22080 atatgacatt aaggcatacc tccctgtaga gcactcagtg gcccgtgctc gtgttgcgca 22140 tcgtcacttg gtttcaggat tatgcgcaac agaagaagag gcaattgaga ggaccgacag 22200 aaatgatatg attaatctca cttttgtcga gaagaacatg gttaccccag atattgtatt 22260 acagcagcta cgtttgaaaa ccgttaaaac atctagtttg taatgtgttt tcatgagtga 22320 taaataaatg agaatgtaat cattcgtgaa atttatcaag aataataaga aaaaatttga 22380 ttacgctgag tcggtgctat tatgactacg gtggtgttca aaaatttaaa aaaaaaaaaa 22440 aaaaggttgg aaaactaaga aatcaaaata accacattgt cccataccac aattcaataa 22500 aggcgaacag gaagcacaca tatatgccac taaatttgag agtactttat cgaagttact 22560 ttgctattgt ttctgatgca tcaaatcctt cggtttggat aacttcaaaa gtatattcaa 22620 tactaatcaa gtaaatttct actctgtggt actccatcaa tgcacaaacc atcattcaca 22680 tgtacccctc atctaactgc aagatggctt aaatcaaaaa agcattgtca attatttctt 22740 gttcttttgt tgatatagta tctaaatccg tcaaaagttt atgttcaaaa atggttatct 22800 aagtggttca atgaagcttt atgtgcttta tctttgctaa agcaataaag gacctccaga 22860 attttttttt cagaagaaac tattaatcta tttttgtttc aagttccaaa cacatatgtt 22920 aagcccaaac cggtttaaaa aaaaagcgct cttcaagtaa taatcaaaac tccagtacca 22980 gctgatccat acaaactcat atctttttta tttttattat ttttctaagc aagaaaactc 23040 ctccacaatt catcaacaag tgtttgctta ctttctttaa actcaaccaa ccactcttag 23100 caaggcatga atgtttacat accttaaatc ttgattcccc agctatgccc agctctttca 23160 aacaaaaagt cgtttcttta actctcgcta tgtacacaac gcaacacgtt ctaattcgtt 23220 gattttttgt tagtaaagtt gccctcatta aaaagttaaa aaagttgaga aatagtaaat 23280 aataacttta cgttcgtacg agtttttaca gtacgttaaa aaaatttagc tttgttctat 23340 tactctttca ttgtttatta ggggctattt ttcaaagatc cccttgaaac aacagtagtc 23400 acgttattgc aattgacttt ttggttgtca gtccttctat accttcccca cttttcctcc 23460 agttcctttg taaagtacat atccatttcc cccagatcat cttccagtca ttaacgaggt 23520 tgttgcatca gtgaacgaag tactttgtat ctcggccaaa cacagcaaca ttcactattt 23580 ctaaaagtac aaaataatac aacacccttc ctcggatgag aggggtataa gtaagagtcg 23640 ctcacatttt ttctaattgc tgccaataac aactattttt gtggtaacga caatccgtat 23700 tgagaattgc tgtatagcta tttatcaaag ctataattat attggaaact tgaaacatct 23760 acgtcctgga tacaattgtt gcatttaggg agttagccat cacgaattgt gttggtaatt 23820 tgtttgcatg tctaacaaac ctgatgccaa tgatcaatgt atggtgaagg agactatctc 23880 ccggatgagt atgagtaaag aaaagccgtt tttgcgtcga aattatagct caccctcctt 23940 taatgattcg gtgaactctg tcaacgatga atttcagact tatcagttgc caaatgggga 24000 gtttagtgac aacatgaacg atttgtattt cccctttcgc aaaggaaatg aatctctaat 24060 gactgagaac tccaattatc ctatttcaga acaggacacc caacataatc atatatcaga 24120 ctttccttcc aggcgcatgc aattggatgg catgaatcac tctaacaatg atacttactc 24180 cacagcgatt ccattttcca aagactcctc cgtatttgat gccgtggggc aacaaagtag 24240 tgttccaatc cacataaacc ctgcatacac taattctcat caaaattctt actctcttaa 24300 tgaaacgtat ttatcttacg attttttcga taatcatcgt ggtgcctctt cgtctgctgt 24360 cagtaaggat ggattggctt ctcctaggcc tactaaggac gtggatgctg acgatacaac 24420 ctggtacttt acctcttcac cttcgtttca gccattgaaa gatagcgatc gttctcagac 24480 aaagaatact catgaagaaa cttctccaat tgtctcatcc cctgaagacg atgctgatgc 24540 agcattcaaa ccctctagcc taccttctac ttccatcagt gcttcatcga atgcattcta 24600 caagccagct gctccagata atgagcggcc gctcgaccct cacatcaccc cttatcttag 24660 gctacaactt cttactactg gagccgacga taatgatatt cggaaaaatg ctctaactca 24720 agtcgattat ttgtcttatg actggaaaga gaccgacata tgggccagct ggcgtgaaat 24780 taccaaaacc aaagctaatt atgacaatgg cattcgtttg gaaaatgctt cttggcgaac 24840 ttggatgaag cacaaattca aactaaaaac catatccccc gaaaccttaa actggttgaa 24900 ggaatgtgac gttacatggc tatatggacc tcttcttcat acctctatgc cgtctaggca 24960 tcattcacat cgaaagaaag agaaggagaa agagaaaagc aaagcacctc gtgttacgcc 25020 attaacccat aaaacaaacg atgatgaagc taatcatagt gaaacgagtt ctggtagttc 25080 tctcgctaaa aaacctattt taaaacgacg aactcctcag gaattgcttc tctctggtcg 25140 tgatctaacc ccgtggcctc aaattaggcg attcgacagt cttttagcca gaaacagagg 25200 cgatattttt tcgaatcgta atcatgccac catccggtct gcactgttta gtcaacgata 25260 tccatctcac tccaagcgcc atattcattt taatgaccgt gttcaacaat gcatcgctgt 25320 cgacattgat agccttccat ctgactccga gagtgcttcc tataataccg atgatgctaa 25380 cagcgttgtg tctccatcga aggatggaat aagtactaca acagtgagtt cagatgctac 25440 tagatctagt cagtccagtc attttcgtat catcgaggac ttgccagatt ccaagctcaa 25500 atattccctg gaggatcaag ctacttacga tcaaagtagc cgttatcctg gtcgacattt 25560 tggaaaaact ggacgcagtc actttcctcg cgcacctgaa tactatggcg aaaatgattt 25620 tgaagaagat gaagtttatc gcgatgatcg acattacgaa aatgagcatg atgaatatga 25680 tcccaacctt atttattatg ataatgaacc cactgaagag aatcggttag tttttgaaga 25740 tactaataat acttttatag acactgatag cgatgactct aatgccgatg agtcacaatt 25800 tttggaatat gcgaatgatt cacctaactc tagtgagtct ttggaatcct taaataacca 25860 atcttattca tcatcgccgt attccgtttt ctctcacccg ccgccatata tgggaagaca 25920 atcattgaac gatagtcctc aaacttctga ctttaaagca tcaaatctca atgactcgtc 25980 ttctaatgtg catagtatct ttcaaacaag ggaaacgact tcaccatccg ttcaaaataa 26040 gacacctact aaatatcaca gagaactcaa aagctcaaaa gatggccatg agcaagcaag 26100 tccattggtc agttcttcac cttctggctc ttttacttct caaatcagtc ctgccgctac 26160 gacaacggct actaatcttg atgccgtttc tcttagtcca tctactgttc gcaccgggag 26220 ccagatttct gatattggaa atgatgctat atctactact cgtaaaacag ttcgtgcttt 26280 tttagagaac gcaaaccctt atagcaccaa taatgacggg aatccgtcaa acaacactag 26340 tgacgttgaa gtcaacgaga cttcaatgaa cgataactct gaagaaccaa tctcctcaaa 26400 ttggttagtg gacttgtttc aaaaatcttt gaaatcattt cgcgaatagt tttgaaatgc 26460 cttcaaaaaa taattattca aatctggagc tttttatttt attgaagtga tgtgacatct 26520 gatttatggt aacagccaag cgttaacaga ccattgtttt ttttccaaaa ttttttgact 26580 ttgctttctt ttgaaaattt ttctttcaaa tgtaaattaa tacttgtatg cagttgagtt 26640 tatcttggtt ttctaaatag cgcattgaat gttgtattac ttccgccggt gatccttaat 26700 ttacttaatc aagtctttac tataacatac ccactaattc caaagttaaa tgaaaatcta 26760 catctttaca cattgttctt acgggccttt atttacaaaa gtgttttata tttcgcagta 26820 agaccttact ttttgatggt gcgaaatcgt ctatccgctc tcatttcttt ttagcattca 26880 tatgaattct attaaaacaa tctttatatt cgcttttcgt tgcaagcgtt catattggtg 26940 tacaccttca taaaattcat ccttttaata aaatctgatt ttctgtcacg agcatttaat 27000 ttacttttcc agaaactgtc tgtatagttc gtgattttag tagtaaatac taagcatgct 27060 agattaaaat acattttttt atattatcaa aaaggattaa atgataatgt attgtactgt 27120 attaccttat gccagtatac ggcgttgtta gttgggacta cttttttgct aaacaaaatt 27180 tctatataag ctgtgactct cttgcatcta aaccaaattt ttaccaacta caaagcttag 27240 attaaaatcc taacttgagt atctttaata aatggtatgt gtctataacc acagatggaa 27300 tctcctgatc tttgatgacc attttttaaa atacaaacta gagtttctga ttaatttatg 27360 atttcaaatt cttgctgagt ttagttgttt ccttctgtat tttggttatt tcaacactta 27420 tgctaacata atttagttat gatacagttt aaactttgca ataaatttct ttcttaaaag 27480 tcaaatgtaa gtgtttgaaa gaattgttta tgttgtgttg gaaaagatga aaaaaacttt 27540 tttttggaat taccggccta ggaatagttt actcctattc cgctgaagaa taaatgtgct 27600 gcaattatgc tgatccatta caatatcaca acttttttta tgggattttc ctattattaa 27660 catcattagt taactgaagc agtctagcat attgatatta tagtatttaa atcatttaat 27720 catggattta atacatacct tttagtttgt atgtgatatg agaaaaattg ttctcaatga 27780 ggaataatta gatgacgagt ctgattcaat atgaagaaaa gactcttaaa attccattca 27840 tgctaactga gagaacaaat ttttaaccta aatctatgcc aatattttac taacataatt 27900 ataggttatt catgaaaggt atccaaaact taattgaaaa ctagacttca aatatgtact 27960 ttagggtatt attaggatga tttattaaat ttcaaagaca agcatatgtc tgatgccatt 28020 ggttttgaag aagtgaaatg cgtctgatta tagacaacct aaagttatat atttccatgt 28080 cctaagtttt cgtgttaaaa caacttttct aacgtatttg caagacctta aactagttag 28140 atacactgaa gttaaggagg ctgttttgta taggtaagta gatcagcttg aggtcgaatt 28200 ttagttcaca tgatgttttt actttaatca cgacggtcta cgtagtttct acattgacga 28260 agattgcctg tgacaaggcg ctttttctga atgtacttta tatatcgacc tctaattttt 28320 agtgtcggtt cgtttattaa cattttttag ttctatagtt tgaatcttct agagttttta 28380 taaagttaat cataaatgaa aatgtcaatc tgacaaacaa aagctaattt tgtaagtaaa 28440 cgtaatattg aacaagtata tgttaaggat tcttttcttt tttctttgaa cagaagggat 28500 ttacgatcaa cactcattta gtgtttcaca tatagattag cgtgctattc tgggtagcaa 28560 tttcgtctcg cagcatgcaa tcaactacga agtggaattt tgccagttta ttagggatcg 28620 atgggcatta tgtgatactc tcaatactgt ggcagcacga gcttttgtta gctactgaat 28680 cttttaaagg ctagaatgaa catactgtgt ttctcaaagt catccaaacc ctcaatgaat 28740 tgtgagtttt gttgtaaagc accttgagga ttcagggacg catctgcaat cagcattgct 28800 ctggaacgta aagtgtttag ggaaatttga accaagctgt cgtctgatat tctacaatga 28860 gttagtaaga ttttgaattt gagaaaaacg tgtaaagttt gacttacaaa tggagcattt 28920 tctcggcaaa atggtaataa tgtgtggtta tgtcccgaat agatacacta ttaggattcg 28980 cctttaatgc atttcgtact acagaagaaa atggtgctgg catatgaata ctaacaaaag 29040 aactataaag taagcaaata agcaaaatta tccaattttc tataagacat tacatgtata 29100 taatgtaaca tgcagaaaaa accaaaaaaa aaaaaaaact ttacttactt aattgctaaa 29160 acctctgcca gccaaaaagg aagttcaact ttagagcccg taggaaccta aactgtttag 29220 aaagtcaagt tctattttta taaacttcac taaccatacg cccttcatgg cctagtcctg 29280 gaatggaaac tgtactagta catggaacct tttgattttc agacaagata ctatcaatat 29340 catagtaatc cattttttta atgtctgagc agaaggaatg atagaagtgt tattgttatt 29400 ttatcaaaat atgttcattt agaaaagttg cagttacaag gtaaaagtag gtagatgcaa 29460 cgataaattc aaatttgagt tggctaagat atagtggata aataatgaac tgtaattaca 29520 ccagtactaa tcaacaaaaa aaatagagat aaaaaagatt tatttttact tttcttaaca 29580 gagcatctag ttcaaaaaat tagtgctgat aaatattgta tgttcgagta ctaaaaattt 29640 gcttcaatgt ttaactcgaa aagtatgtca tacatgtgta tattcgtcct tctgaaattg 29700 gtcgaaaaat tttattaaaa aaaggaaact ttgttctata gtttcattaa agaaacgcat 29760 atgcttgttt gaatgttata cctatttatg aaacttgctc attatgcgat caaaatttac 29820 acaatctttc cgtaaaactg atttttttaa atgattttta gtccgtaatc tacaaaacat 29880 gattgcattg tattcaaaat tattttgcgt attaattatt tagtatgtca tttccaaatg 29940 caaaaaggtt ttaacaccga cataggccaa atttcataag ttattcgcca agtttcatca 30000 acaggttcat caagtcatat acgctttaat ccatacttta gatgtcaaca ccttcgagtt 30060 tatcagcaat ctttacctga gtaaataatc aacctgctgc caaacaatgt tgtaaaatca 30120 aagcaacaat ttgttgttcg tttaattagt tactcataaa attaaagaga actcagagtt 30180 tacttggaag gtaaattaaa tagaagtacc ccgccaacta taaacaatta gtttcaaagg 30240 ttaagcagac taggatatac aggaacttta catccaagac atcatcaaat atgctattcc 30300 cccaatgtta tacgcaacaa atggatgcct tcgtaagaat tgatatcgac gtttggtgaa 30360 cacagcacga aacgttaaaa acttattcac tactttttgg agaagtacgc atcttccaaa 30420 tgtcttcact attcggccct tgcctaaact tcatccactg ctgaagacgc cgcttacgaa 30480 gcccttcttg agcctcttcg tgagccttcg acttggttga cagacaccat ttaaagtctt 30540 taaaatttcc cttacatctg ttgtattcac cataacgata gtaatgattc atttgtgaga 30600 acactgttaa acacatggcc atttggtcaa agtaatactg taaactacac ggatcctcag 30660 gaatcccttt tttcaagtcg agtattttat ctagttccgc atactgacca aaagtgcttt 30720 tttcatcatt ttctttaaaa ttattcatta tttaaaagca tactagtaaa aatcaagtga 30780 attgtgccta ggataggtag ctaacgtgac tgccactgaa cctgtgtagc gtattagatc 30840 catcaagatc ccttctgctc atatcattgc tgatctgtaa attgaccgca tcaaatttga 30900 tctcatttat atcgagattg atctatatta ttttgccaat ttgcagtata taaacttatt 30960 tgattaagtt tttggtctcc ttcgccacgt cttcattttg ttagtttaaa tttttttgac 31020 taacttagaa agggaagttt ttaaaaacgt tgaaatactt tttcgattta aaaatatata 31080 tttaattaat tttctgttcc aaaatggttg ctcctcatct ttggttacgt gctgaaacca 31140 aacctttaga agagcgcagt gctttgactc ctagaactgc caagatactc gccgatgctg 31200 gatttcaaat taccattgag cgctcttccc aacgtgcttt caaggacaaa gaatttgagc 31260 gccttggttt ccccatggtt cctgagggct catggcgaca tgcacctaag gacgcgtaca 31320 ttattggtct caaagagctt ccggaaaatg ataacagtcc tttgaagcat actcatattc 31380 aatttgctca ttgctacaaa aaccaggaag gttggcgtga agtcttgtcc cgattccccg 31440 ctggcaatgg tcttctatat gatttggaat ttttgcaaga tgacaatggc agacgtgttg 31500 ccgcttttgg ttaccacgct ggttttgctg gatcagctat ctcatgttta gtttgggcac 31560 atcaattatt gcatcctaac aaacaattcc ctgctatccg tccgttcccc aacgaaaaat 31620 ctttggttcg ccatgttgct cgtcaagtac gtttagcttt gaaaaagaat aacaaccagt 31680 atcctcgtat tctggttatt ggggctcttg gtcgttgtgg tactggagcg tgcgatttag 31740 catcaaagat tggtattccc ttcgataaca ttcttcgctg ggacattaat gaaactaaga 31800 agggtggtcc ctttaccgaa attacggaat cagacatatt tgttaactgc atttatctga 31860 gcatgcctat tcccaaattc tgtaccgtcg agtcgttaaa tgtacctaac cgtaaattgc 31920 gtgttgtttg tgatgttagc tgtgacacta ccaatcctaa caatcctatt ccaatttata 31980 atgtaaacac tacatttgat catcctacag ttgaggttaa aggtgtcaca actcctcctc 32040 ctttagaggt catttctatt gatcatcttc ctactttatt gccaagggaa tcttccgaag 32100 catttagtga agctctaatt cctagtcttt tggctttgaa ggacgtcgac aatgctcccg 32160 tttgggtcag agctaaaaaa ctttatgaaa ccatggttca aaagctttaa aataaatgtt 32220 atttaatttc aaagttccgg gtcctttata ttgtttcacc aaattattga atattatttt 32280 ctcaaaaatt aactttagaa tacaatttag acggcatttt cgatgctctg gacatttttt 32340 ccacgtactt gttaaattgt agcggtgttg cataatacta ccttttgatt tgttattcac 32400 gttacaatat atatttgact aatttaaata tgataatata cacatttctc tgcaaacctc 32460 ctttatactt ttcgccggtc attgattaat aattaagaaa caggatttca tcctgcattt 32520 gccacttacc tatatggtaa atataaatct tgaaactttc cccaatattt attgcttgcc 32580 ttacgaagtt aaattatagg cacagacatc tttggcattg gaaagattta gtaacaatca 32640 taatgtagca cttcttaaaa aatctaattt tagaacaaaa aggcttaaaa aagaatggtt 32700 ccgctctttt aaaaaatagt aaaatgtaca atagcaaggt tttcgtaggt cgacggacat 32760 aacaagggga aagagaaata aagcatgtaa acgtcaata 32799 //