ID SPAC21E11 standard; DNA; FUN; 12854 BP. XX AC Z67999; XX SV Z67999.1 XX DT 20-NOV-1995 (Rel. 45, Created) DT 01-NOV-1999 (Rel. 61, Last updated, Version 6) XX DE S.pombe chromosome I cosmid c21E11. XX KW 60s ribosomal protein; acetyltransferase; auxin induced protein homologue; KW b zip; BZIP protein; cyclophilin; eif-2b; Homol D box; L2; L8; lcb2; mts2; KW pcr1; peptidyl-prolyl cis-trans isomerase; rp18-1; rpk5; KW serine palmitoyltransferase; sexual development; transcription activator; KW transcription factor; translation initiation factor. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-12854 RA McLean J., Harris D., Wood V., Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (16-NOV-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL barrell@sanger.ac.uk XX DR GOA; P08093; P08093. DR GOA; Q09923; Q09923. DR GOA; Q09924; Q09924. DR GOA; Q09925; Q09925. DR GOA; Q09926; Q09926. DR GOA; Q09927; Q09927. DR GOA; Q09928; Q09928. DR SWISS-PROT; P08093; RL2_SCHPO. DR SWISS-PROT; Q09923; YAKC_SCHPO. DR SWISS-PROT; Q09924; E2BD_SCHPO. DR SWISS-PROT; Q09925; LCB2_SCHPO. DR SWISS-PROT; Q09926; PCR1_SCHPO. DR SWISS-PROT; Q09927; PPR1_SCHPO. DR SWISS-PROT; Q09928; YAL5_SCHPO. DR SWISS-PROT; Q09929; YAL7_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c21E11 Cosmid c21E11 is overlapped at the 5' end by cosmid CC c1F7 and at the 3' end by c2C4. XX FH Key Location/Qualifiers FH FT source 1..12854 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c21E11" FT /map="IR" FT CDS 1..238 FT /codon_start=2 FT /db_xref="GOA:Q09923" FT /db_xref="SWISS-PROT:Q09923" FT /label=SPAC21E11.01 FT /note="SPAC21E11.01, len:>78, SIMILARITY:Arabidopsis FT thaliana, O22712, f8a5.26 protein., (374 aa), fasta scores: FT opt: 201, E():7.2e-08, (40.8% identity in 76 aa)" FT /partial FT /gene="SPAC21E11.01" FT /gene="SPAC1F7.12" FT /product="conserved hypothetical protein" FT /protein_id="CAA91961.1" FT /translation="PGQLSLAWLLAQGDDILPIPGTKRVKYLEENFGALKVKLSDATVK FT EIREACDNAEVIGARYPPGAGSKIFMDTPPMPK" FT misc_feature 1..950 FT /note="nominal overlap with cosmid c1F7 EM:Z67998 S. pombe FT chromosome I" FT CDS complement(807..1568) FT /db_xref="GOA:P08093" FT /db_xref="SWISS-PROT:P08093" FT /label=rpk5 FT /note="SPAC21E11.02c, len:253aa" FT /gene="rpk5" FT /gene="SPAC21E11.02c" FT /gene="rpl8-1" FT /product="60s ribosomal protein K5" FT /protein_id="CAA91962.1" FT /translation="MGRVIRAQRKSGGIFQAHTRLRKGAAQLRTLDFAERHGYIRGVVQ FT KIIHDPGRGAPLAKVAFRNPYHYRTDVETFVATEGMYTGQFVYCGKNAALTVGNVLPVG FT EMPEGTIISNVEEKAGDRGALGRSSGNYVIIVGHDVDTGKTRVKLPSGAKKVVPSSARG FT VVGIVAGGGRIDKPLLKAGRAFHKYRVKRNCWPRTRGVAMNPVDHPHGGGNHQHVGHST FT TVPRQSAPGQKVGLIAARRTGLLRGAAAVEN" FT misc_feature complement(810..1535) FT /note="Pfam match to entry PF00181 L2, Ribosomal Proteins L FT 2" FT promoter complement(1638..1646) FT /note="Homol D box" FT CDS complement(2553..3068) FT /db_xref="GOA:Q09926" FT /db_xref="SWISS-PROT:Q09926" FT /label=pcr1 FT /note="SPAC21E11.03c, len:171aa" FT /gene="pcr1" FT /gene="mts2" FT /gene="SPAC21E11.03c" FT /product="b zip transcription factor pcr1" FT /protein_id="CAA91968.1" FT /translation="MTAKKKEVDDEKRRRILERNRIAASKFRQKKKEWIKELEQTANAA FT FEQSKRLQLLLSQLQQEAFRLKSQLLAHQGCQCSVKIRSVLTDFQTAHNALHSQHMAYR FT PVQPPPGDNMLESVVSVSPTQMHPSLQGLPPNQHPQMPPSSQQPNSDDVQQHMFSAAGL FT PRSLGGPI" FT misc_feature complement(2859..3035) FT /note="Match to PF00170 bZIP, bZIP transcription factor FT Score 44.64" FT CDS 5010..5639 FT /db_xref="GOA:Q09927" FT /db_xref="SWISS-PROT:Q09927" FT /label=SPAC21E11.04 FT /note="SPAC21E11.04, len:209, SIMILARITY:Saccharomyces FT cerevisiae, SP10_YEAST, spt10 protein., (640 aa), fasta FT scores: opt: 319, E():8.6e-15, (39.3% identity in 117 aa)" FT /gene="SPAC21E11.04" FT /product="putative transcriptional regulatory protein" FT /protein_id="CAA91963.1" FT /translation="MKDPNTIPPWRCTDFNAWCIAVDKSTNVKNKEELLSTLTYFINYE FT IEMGQTYPIDIKMTRNEAEDFFFKFCTVICVPVESETSPAPDLATASIDWKTSLLGAFY FT IKPNYPGRCSHICNGGFLVSPSHRSKGIGRNLANAYLYFAPRIGFKSSVFNLVFATNIK FT SIRLWERLNFTRAGIIKDAGRLKGHEGYVDAYIYQYHFPSLEDALK" FT misc_feature 5151..5531 FT /note="Pfam match to entry PF00583 Acetyltransf, Acetyltran FT sferase (GNAT) family" FT CDS join(complement(7564..7578),complement(7423..7484), FT complement(6368..7282),complement(5879..6302)) FT /db_xref="GOA:Q09928" FT /db_xref="SWISS-PROT:Q09928" FT /label=SPAC21E11.05c FT /note="SPAC21E11.05c, len:471, SIMILARITY:Dirofilaria FT immitis., O61300, cyclophilin dicyp-3, (527 aa), fasta FT scores: opt: 1123, E():0, (40.4% identity in 488 aa)" FT /gene="SPAC21E11.05c" FT /product="peptidyl-prolyl cis-trans isomerase" FT /protein_id="CAA91964.1" FT /translation="MGGMVPFNHPCCLVDETKQAIIFDFRFIVPWLRKHGTNPINGQKA FT SMSDLIKLKFAKNSAEEYCDPVTMKSFTRFSHIVAIRSTGNCFSWDTIERLNIKPKHWR FT DLVNEEQFTRDDIITIQDPHNVENRDFSAIQKQKETARDEKITKAKIALQASRAKSTES FT TSSPELSHSLDSSKSIASDMPIHRASHTTGYAAASLTSTSFTPVTKNERAIIAEEDYML FT NHTRIKHKGYARIVTNHGEINIELHTDYAPHAVYNFVQLAKQGYYRNTIFHRNIARFMI FT QGGDPSGTGRGGQSIWGKPFKDEFCNPLKHDDRGIISMANRGKNTNGSQFFILYGPAKH FT LDNKHTIFGRVVGGLNVLDALEKVPTNSNDHPKLPIKLEDIIIFVDPFEEWKKDEREKE FT KRKRQEEEEENNLDRTSWTGRDLSASSTDHSLNASVGKYLKKEVSLEEKTFTSTVNPKK FT KKARTGFGNFDAW" FT misc_feature join(complement(6368..6672),complement(6152..6302)) FT /note="Match to PF00160 pro_isomerase, Cyclophilin type FT peptidyl-prolyl cis-trans isomerase Score 182.20" FT misc_feature complement(6303..6318) FT /note="ctaacctgatttatag, splice branch and acceptor sequenc FT e" FT misc_feature complement(6362..6367) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(7283..7296) FT /note="ctaacatgtgttag, splice branch and acceptor sequence" FT misc_feature complement(7417..7422) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(7485..7510) FT /note="ttaattattgctctctttccttgcag, splice branch and accept FT or sequence" FT misc_feature complement(7558..7563) FT /note="gtaaga, splice donor sequence" FT CDS 7885..9288 FT /db_xref="GOA:Q09924" FT /db_xref="SWISS-PROT:Q09924" FT /label=SPAC21E11.06 FT /note="SPAC21E11.06, len:467" FT /gene="SPAC21E11.06" FT /gene="tif224" FT /product="translation initiation factor eif-2b delta FT subunit" FT /protein_id="CAA91965.1" FT /translation="MGFSAEQAKKDGKDQSPVSESSSVGGTSPATASSVVSPNEPKLSG FT KEAKALKKARKQASRRAKAEAAAANNPPGVSEEKKVAIPNKNSNQQKKASKQNPQNSPE FT TDANLQEKKIFEEKQVSIFSHLDWRRRRTTENIPKDIHPAVIRLGLKLANYKIFGSNQR FT CIDLLKTFKIVIQDYQTPYGTTLSRHLTTHINSQIAYLVSTRPLSISMGNAIRFLKLEI FT SVLDIDLTDDEGKELLLEKIDSYIRDRIIIAGQVIVQAATEKIQDGDVILTYLHSSTVN FT DVLIHAKNVGKKFRVVVVDSRPEFEGRVCLKLLTEHGIECTYVMISALSYIMQEVTKIF FT LGGHAMLSNGALYSRAGTSLISLLGHESNVPVIACCESYKFTERIQLDSLVYNELAPGD FT QLVNMGVDDFEEKPGVLANWKSVKNLKLLSLKYDVTPPRLITVCVCEMGLLPSTSVPAI FT INEFKQVYA" FT misc_feature 8005..9246 FT /note="Match to PF01008 IF-2B, Initiation factor 2 subunit FT Score 704.14" FT CDS join(10250..10444,10500..11282) FT /db_xref="SWISS-PROT:Q09929" FT /label=SPAC21E11.07 FT /note="SPAC21E11.07, len:325, SIMILARITY:Rickettsia FT prowazekii., Q9ZD79, hypothetical 33.3 kd protein., (285 FT aa), fasta scores: opt: 277, E():6.6e-11, (29.6% identity FT in 311 aa)" FT /gene="SPAC21E11.07" FT /product="hypothetical protein" FT /protein_id="CAA91966.1" FT /translation="MNRFTVRSKFIKFSFQLFRNYSVCLNSSKSLIRVEGVDAVKFLQG FT LTTNKITLDNPVYTGFLNTQGRVLFDSFIYPKVSNNGTENERSDELYVEIDKVAESDFL FT KHLKKYNLRSRCSIAKIPSEELSIKVIWDVKEESRLKDTVAYAKDPRFSKQRLLRMIVP FT TSTCTSSSSGSLDDYKVFRYRNGIPEGPQEIIPSISFPLESNMDWMKGIDFHKGCYLGQ FT ELTVRTYYTGVTRKRIFPFIIPNYEDNPSQVIEPSAPLSIVAKQGEPVSRRSPGKIIAI FT LGKVGLALVRLQYLKSDLACNGIPIQLNTSIWLDELSSTPSENS" FT misc_feature 10445..10450 FT /note="gtaagg, splice donor sequence" FT misc_feature 10488..10499 FT /note="ctaacttactag, splice branch and acceptor sequence" FT misc_feature 11069..12854 FT /note="nominal overlap with c2C4 EM:Z99259 S. pombe FT chromosome I" FT CDS 12037..12852 FT /db_xref="GOA:Q09925" FT /db_xref="SWISS-PROT:Q09925" FT /label=lcb2 FT /note="SPAC21E11.08, len:272" FT /partial FT /gene="lcb2" FT /gene="SPAC21E11.08" FT /product="serine palmitoyltransferase 2" FT /gene="SPAC2C4.02" FT /protein_id="CAA91967.2" FT /translation="MAQADFVSPTSIDVSEKKEVEFHKKVDHVENPPLSTESAKLEAEE FT VAAEKLNSEHLLENEFAPITDPTHRRVSKNPDGAELFQFEDEPSYYYVVATYLTYLVLI FT IIGHVRDFFGKRFHKDDYKYLKDNDGYAPLYNHFDNFYVRRLQHRINDCFSRPTMGVPG FT RVIRLMNRYSTDSNSTFKLTGDTSLALNVSSYNYLGFAQSHGPCATKVEEAMQKYGLST FT CSSNAICGTYGLHKEVEELTANFVGKPAALVFSQGFSTNATVFSTLMCPG" XX SQ Sequence 12854 BP; 4105 A; 2344 C; 2426 G; 3979 T; 0 other; acctggccag cttagtttgg cttggttgtt agcccaaggt gacgatattc ttcccattcc 60 tggtaccaaa cgtgttaaat acttggagga gaactttggc gctctcaagg ttaaattatc 120 cgatgccact gttaaggaaa ttcgtgaagc ttgtgacaac gctgaggtaa ttggtgctag 180 atatcctcct ggtgctggat ccaagatttt catggatacc cctcctatgc ccaagtagat 240 ttagtctttc tcgtatatgg ttttaaaatt gtgcatgttt atagttacct tcatttatgc 300 tggaagaaat gaaatgaatt tttgttagtt gtgcattgtc atacatcgag gaagtgtaca 360 gatttccaat tttcaatgat tgtagcagaa tgccgaaatt aacatactaa agtatccgta 420 acaactgata gtttataaac ttaaaagtca tgagttaaat gcattacgaa actagcccac 480 ggtactaatg ccatgaaatt atgaacaatc gccggcaagt attctagtac tcttggctgc 540 taaaaagccg gatttaagtg cactacacaa aacagttaat caagttttga aaatttgatc 600 gttattaata gcatagtaca ttgagaaact ctttgacaat taaattggat gtttacatgt 660 gggtttacaa gcttaatatg ctcttgggtt acgcatacac catacctacc aagactacaa 720 cgaagcaaat ctactcacta ctaaagacta tcaacacatt ttcacactgt ttactgccag 780 aaaatatata ttttgattga ggaggtctaa ttttcgacag cagcagcacc acgcaagaga 840 ccagttctgc gagcggcaat gagaccaacc ttttgaccag gagcggattg gcgaggaaca 900 gtggtagagt gaccaacgtg ttgatggtta ccaccaccgt gaggatgatc gacggggttc 960 atagcaacac cacgagtacg aggccagcag ttgcgcttaa cacggtattt gtggaaagca 1020 cgaccagcct tgagcaaagg cttgtcaata cgtccaccac cagcgacaat accgacaaca 1080 ccacgagcag aagaggggac aacctttttg gcgccagagg gcaacttaac acgggtcttg 1140 ccagtgtcaa catcatgtcc gacaatgata acgtagttac cagaagaacg acctaatgca 1200 ccacggtcac cagccttctc ctcaacgttg gagatgatag taccctcagg catctcacca 1260 acaggcaaga cattaccaac ggtcaaagca gcgttcttac cgcagtagac gaattggcca 1320 gtgtacatac cctcggtagc gacgaaggtc tcaacatcgg ttctgtagtg ataagggtta 1380 cggaaagcaa ccttggccaa aggagcaccg cgaccagggt cgtgaatgat cttttgaaca 1440 acaccacgaa tgtatccgtg acgttcagca aagtccaagg tacggagctg agcggcaccc 1500 ttacggaggc gggtatgagc ctggaaaatt cctccactct ttctttgtgc tctaataaca 1560 cgacccattt ctggtgtttt ggttgttgga gaatacggta ttgaggttgc aaattcaagt 1620 ggtgaattgt tgtaaaatgt gactgttttc ggtcatccaa aattttttga cttaagtatt 1680 atgcatttcg ttaatggaaa gcctaacgag aaaaaaaatt ggtgcgaaat catgtgaata 1740 acgagatgca tgtaatttac cgtacctccc taaattctta ggagtgctat actgttgaga 1800 gcagtagaaa tggaacagat tggataaatg agataaattg taataacgtg aatatttatt 1860 tatttacata atgaatgcag ttgggaaatt aaagaaagtg atgctttaac gcagacactt 1920 cttttgcatc atgatacacg gattgtggta taaataactg aaagaaaaaa agagacattc 1980 tactgtttac aaataaaatc aacagcatac cacagttgct ccaaccagag ctttttaaaa 2040 aaaaaaacca aattaatagc ttaagatctt tttttcagtt tgccaaatga aattataaat 2100 ctgtacattt agaaagaaga acatttttta tgttttaggt aactgacgag aataggcaat 2160 ctggcaatag ttcaagaaat caaatcaaat acatcgaaga agtaagtgga gatgtagcaa 2220 gcgcaaagtc atacttcaaa gaagtttata agcatcgtaa agttattttc ttttcacatt 2280 tcataaagac aaatattttg aaaacccggc gaggaaattc gaaataataa tagataaagg 2340 tcataacaaa gaaaacgtct gtgcaaaaaa ataataagga cagaaatttg aaaagaattc 2400 catatgcatc ggtaattcaa cacttaaaaa cgcccgactg tcatctagga gagaacatta 2460 ggctaaaata ggagccataa atctacatgc aacatcacat taaaatcaat tgctttattg 2520 taaagggggg taatgaaaac aaatgttctt tttcagatgg gcccaccaag ggatctagga 2580 agcccggctg ctgagaacat atgttgctgg acatcatcgg aattaggctg ctgagaagaa 2640 gggggcattt gagggtgttg atttggaggg agaccctgca atgatggatg catttgagta 2700 gggctaacgg aaaccacaga ttcaagcatg ttatcaccag gagggggttg taccggccgg 2760 taagccatat gttgagagtg gagagcattg tgagcagttt gaaagtctgt taggacagaa 2820 cgaatcttta cactacactg acaaccctga tgggcaagta attggctttt cagccgaaaa 2880 gcctcctgtt gcaactgaga cagcaataac tgaagacgct tggattgctc aaaggcagca 2940 ttggcagttt gctctaattc tttaatccac tctttctttt tctggcgaaa tttagaagcg 3000 gcaatgcgat tgcgctccag aattcggcga cgcttttcat catcaacttc tttttttttg 3060 gcagtcatct taaataatca atgtatagaa aagggggaat cagatgatca caaacaaaaa 3120 tataacaaag gaaacaaagg gggagatggg aaattgaaat gaaaaaaaaa gtaagaacga 3180 aaaaagaaat accctaaagg atatatttta atttaaagga aactcctact tggtgaatac 3240 aacacgcagt aaagaattag cacgacacac gcgcgaaatc aggaggaagc aaattagacg 3300 gagatagcca gtttctaaag gaatacagaa gaatgacaag acgtcaagaa acgtcaattc 3360 tatagaagcg ctagtcttct aagattaaaa acacacacgt gggggaatta attcgtaagt 3420 aaaccgaccc ctaaaatttt ttgtaatctc acgacacacg tcaaatgtac agcgcacacg 3480 ttgacccaaa attaactaac aaaggagatc ccaaacgact tcaataaata cgttgatatg 3540 ttatactctc tgaaaagtta tacaaacact tgatttgcaa ggatgtctca ccaaactacc 3600 aaattaactg tttaatgacc cagaaaaagc gaatccactg tgaaaaccga ataaattaag 3660 aaaatttagt atttaaaaat caaattttaa caactctgta gaatgaaagg attttaccct 3720 tttacaatgg tataagctac aatggaccat agacggaagt ggtcaaagag atgattatat 3780 aggatgatca atgctcgatg catgatgtca tcgacaagga ggctgtaatt atatcgataa 3840 acagaataac gagagttagt gaaatttaat acatggccga ttttgatgta aataaaggtt 3900 agtggacttg cgaagaaaga cagacacaat tgagaaaata aaaagaaaaa tattttaaaa 3960 aaaagaaaca atactaaaga aaattgactt gcaaatgaat tgtgagagac gtggatacaa 4020 aagacgaaaa agcatcggtg aatttaaaag aaccaaaaat gaggcgaaca attttaattt 4080 ggttgatgga aatgaatcat ttgattaaaa gtgaaaattt ttaaattatt ttagaaatgt 4140 aaatatttta tccttgtgcg aacgtaaaat tggtaaaata aattttaaag attttaaata 4200 attaaaaaac tctagcaaaa atatagtcaa ttccaaagta actgcatttt aattcgtttt 4260 attattaaaa caggaggttc aggtactgca cttaatataa atatattaat tgaattgtgt 4320 ttttttggaa tttgtataat taattatttt ccaataccac taacctaaaa atttcgcatc 4380 ttcactttat actgtacttc attattttta ttatcatctc acatgtattc ttcactattt 4440 aataaacaat aaaagaatat gagaaattgc aatgagtgaa taaagaaaag acaattaata 4500 tcggattctt cattcgttaa caaggaagaa agacttaatc tatagcaccg aaatattaaa 4560 ccgtttccat tagcttgatg tagaagtcga tctaatgttt cgcaaaccga aaatacacag 4620 acatgaatat gtacaagcat taaccaagca tacagaaaat cgaaaatcat ctaatacatg 4680 aataatgaga gctttattac ttcgtctcgc tttcatattc taaaatactt aattatttgc 4740 ttctaacaaa taacgctttt taccgtactc taggaattac ttgcaacaga tttcttcctt 4800 gcatattttt aatcatttga tttatctctt cgacttgatg attttatcac attatttctg 4860 tatatcatac agttgtttcc tgttgtatat caagatggca tcttgatgag tttgagtgat 4920 gataatttat ctatgtgttt gtcgcttaaa ttatctactc cacatggcta taaaatccct 4980 ttaattttgt tcataatcca tatcccaaca tgaaggatcc aaatactatt cctccatgga 5040 gatgtactga ttttaatgct tggtgcatag ccgttgataa atctacaaac gttaagaaca 5100 aagaagaatt actcagtacc ttgacttatt tcatcaacta tgaaatagag atgggacaga 5160 cttatccaat cgacattaaa atgactcgca atgaagcgga agactttttt tttaaatttt 5220 gtactgtaat ctgtgttcct gttgagagtg agacatcacc tgctccagat ttggctacgg 5280 cttcaattga ctggaaaacg agcttactcg gtgccttcta cattaagcct aactatcccg 5340 gtcgatgctc tcatatttgt aatggtggat ttttggtttc acctagtcac cggagcaaag 5400 gcattgggcg taatttggcc aatgcctatt tgtactttgc tcctcgaatt ggtttcaaat 5460 caagcgtgtt taatctcgtt ttcgctacca acataaagag cattcgacta tgggaaagac 5520 taaatttcac acgagccggt attatcaaag atgctggtag acttaagggt catgagggat 5580 acgtcgacgc ttacatatac caataccatt tcccttcact tgaagatgcc ttaaaataaa 5640 cttcctttac tttttcacaa atttgcaatt ctctcctttc aattttggat gccacacttt 5700 cgatagcagt ttgttttaag aggcaaaggt tcaatatttg ctgcctgcga agcttcttac 5760 tgtacaacaa aatgttcaat aaatgatatg atattaaaaa accttataaa ctcagaaata 5820 atttaacaag tcccgtatat taagttgttt ggtatatatt tcgtttgact tagtaagttt 5880 accatgcgtc aaaatttcca aatcctgtgc gtgctttttt ctttttggga tttacagtag 5940 aagtgaatgt cttttcttca agtgatactt ccttttttag atattttcca acagacgcat 6000 ttagagaatg atccgtagaa gacgccgata aatccctccc agtccaagaa gtgcggtcta 6060 aattattttc ctcttcttct tcttgtcttt ttcgtttctc cttctcccgc tcatcttttt 6120 tccactcttc gaatgggtct acaaatatta tgatgtcttc aagcttgatt ggtaacttgg 6180 ggtgatcatt actgttggta gggacttttt caagagcatc caaaacattt aaaccaccga 6240 caactcgacc aaatattgta tgtttattgt ccaaatgttt cgctggtcca tacaatataa 6300 agctataaat caggttagca cttgcatttc tttgaagctt ttaaaaaata gagaagaaaa 6360 cacttacaat tgacttccat tggtattttt tccacgattg gccatagata taattccacg 6420 atcgtcatgc tttaaagggt tacaaaactc gtccttaaac ggcttgcccc aaatactttg 6480 accacctctt ccagttccac taggatcacc tccttgaatc ataaatctag caatattgcg 6540 atgaaaaatt gtattacgat aatagccctg cttggcaagc tggacaaaat tgtaaacagc 6600 atggggtgca tagtctgtat gcaactcaat attaatttct ccgtgattag taacaatacg 6660 cgcgtatcct ttgtgcttga tccgcgtatg gttaagcata taatcttctt cagcaataat 6720 tgctctttca ttcttcgtta caggagtaaa tgatgtggag gttaaggaag ctgcagcata 6780 accagttgta tgggatgcgc gatgaattgg catatcagaa gctatagatt tagatgaatc 6840 gagagaatgc gataactcag gtgatgaagt tgactccgtt gacttggcgc gagatgcttg 6900 taaagcaatt ttggccttgg ttattttttc atctcttgcg gtttcctttt gtttttgaat 6960 ggccgaaaaa tctcggttct caacgttatg aggatcctgg atggtaatta tgtcgtctct 7020 ggtaaattgc tcttcgttca cgagatccct ccaatgtttt ggttttatgt tcaaacgttc 7080 aatagtatcc caagaaaaac aattccctgt agaacggata gccacgatgt gtgaaaagcg 7140 cgtaaagctt ttcatcgtaa ctggatcaca atactcttca gcactgtttt ttgcaaactt 7200 gagctttatt aaatctgaca ttgatgcctt ttgtccatta ataggattag taccatgttt 7260 tcgaagccaa ggaacaataa atctaacaca tgttagcgct catcaccact tttttatgaa 7320 gaatgaaaga tttccaaaag caactagatt agttggtaaa caaatatcat ttaataccaa 7380 aaaatttgct tcgaaactca catctaatag tgatttacat acctaaaatc gaaaataatg 7440 gcttgcttgg tttcatccac aagacaacaa ggatggttaa agggctgcaa ggaaagagag 7500 caataattaa aaggaagttg tttgtaactt gtggtactgt tcttttgggc tatgcactca 7560 taccaccatg ccacccatgc acacccgaat gctcagtttg tgtaatgtac agtttgtctg 7620 tatttttgcc cattcctgtt aataaatatc ataaatacgt ttgtacggtt ataaaaaata 7680 aaaataaaag ttcttaattt tatgatattt taaggcgata aagtaattaa tttctagtaa 7740 tatatatgcg aactacaagt atacgttgtc gaatagcgtt ggtgtagtaa gggtaaggtc 7800 actaagcgca cgttgggtgt tatagctaaa ctcatctacg cttctaccaa aacaaaccaa 7860 tttaatagaa atattgattt tctgatgggg ttctcagcag aacaagcaaa aaaggatggg 7920 aaggatcaaa gccctgttag tgaaagctct agtgtgggag gaacatctcc agctacagct 7980 tcttctgtcg tttctcccaa tgagccaaaa ctttcaggga aggaggcaaa agcgttgaaa 8040 aaggccagaa aacaagcaag tagaagagca aaagccgaag cagctgccgc gaataatcca 8100 cccggtgttt cagaagaaaa aaaggtagct atccctaata aaaatagtaa ccaacaaaag 8160 aaggcatcga aacaaaaccc gcagaatagt ccagaaactg atgctaattt gcaagaaaaa 8220 aagatttttg aggaaaagca agtttctatc ttttcgcacc tcgattggag acgtcgtaga 8280 accactgaaa atattccgaa agatatccat cctgctgtta ttcgtttggg tttaaaactt 8340 gcaaattata agatttttgg atcgaatcag cgctgtattg atttgttgaa aacttttaaa 8400 atcgtcatcc aagattatca aacaccctac ggtacgacgt tgagcaggca tctgaccacg 8460 catataaatt ctcaaattgc ttatttagta tcaactcgtc cgttgagtat cagtatgggg 8520 aacgccattc gctttttaaa actcgaaatt tctgttttag acattgacct taccgacgac 8580 gagggaaaag aattgcttct ggaaaaaatt gacagttata ttcgcgatcg tattatcatt 8640 gcaggacaag tcatcgtaca agcagcaacc gaaaaaatac aagacggaga tgtcatttta 8700 acgtacttgc actcttcgac agtaaacgat gttctcattc atgctaagaa tgttggtaaa 8760 aaattccggg ttgtcgtggt agactctcgt ccagaatttg aaggccgggt ttgtttgaag 8820 ctgttgaccg agcatgggat tgaatgtacc tatgtcatga tttcagcgct ttcctatatc 8880 atgcaagaag tgaccaaaat tttccttgga ggccatgcta tgctttcgaa tggtgctcta 8940 tattctcgtg ccggtacctc tttaatttcc cttttgggac acgagtctaa tgttccagta 9000 atagcgtgtt gcgagtctta taaatttact gagcgcattc aattggattc gttggtatac 9060 aatgaacttg cacctggcga tcaacttgta aacatgggtg tggatgactt tgaagaaaaa 9120 cctggtgtac tcgcaaattg gaaaagtgtt aagaacttaa aattactcag tctaaaatac 9180 gatgttactc cacctcgtct aattactgta tgtgtttgtg aaatggggct tttaccttca 9240 acctcggtac cggctatcat aaacgagttc aaacaggttt atgcttaatt tctctaattt 9300 ccttttgttt ttttgtttcg tccacctcag aggtaattta tgagcatatc catgtttgct 9360 tccttgaagt acctttcatt ttccctttgt tatttctcat tcctttctca atgcttggaa 9420 gatttggttt gtgtgaaaat aaaaaattca ttatatttaa atttacaaaa gttcattgtt 9480 tactcttttc ttaaaggaac ctaaactgtt ctaatttttc catgtagatt atatattggc 9540 atttaaattg tctcaacatg atttttgaca tattggtata tccaagggga gctattggca 9600 tggttaagag taatgatgtt cttttgttgt attaatggtt aatatttgta gatgaaatga 9660 aatgagcagg gatcgtacaa tgtcatttca tcacttcatt tccggctata gtatgctgat 9720 gcttcggata tatcggagaa aacttgcaat ctcttttttt ttaagacaca aaatagaaag 9780 ctgttactcg atattcaatt tttttttttt taaattatag aactgatgtt cgaagctgaa 9840 ataaaatttt gcatcacaag ctttacgctt gatgtcagct tatgatctaa aacctgtaat 9900 aatttaagag cgattctagt aataaacacc agaattaaat attatttttt taagaaaagg 9960 gaaattttgt tcctcatcga agaaaattca tcttcagtat gttttgacct taggtttttt 10020 tcctacagtg atattactgt attgcaaaca aataataata tatatcttta taatatacac 10080 taataatttt gccatatcct ccttggattc ccccgaaaag taacaaaaac aatgtgatgc 10140 gaaatcatca tctcaaccac ttatcgattt tagaaattcg gtttactgta aaagagtcct 10200 attctagcct caggaaacca agtgaattca agtactttac ctatgggcaa tgaataggtt 10260 caccgttagg agcaagttta taaagttctc attccagcta tttagaaatt acagcgtttg 10320 tctaaattca tcgaaatctc tcattcgtgt tgaaggagtt gatgcagtca agtttcttca 10380 gggcttaacg accaacaaaa taactttaga taatcctgta tacacgggct tcttaaatac 10440 acaggtaagg agcttgcggt gttgggttta atgatgcgcg atgtattcta acttactagg 10500 ggcgagtatt atttgattcc tttatatatc caaaagtctc caataatggc acggaaaatg 10560 aacgatctga tgaattgtac gttgaaattg acaaggttgc agaatccgat tttttaaaac 10620 acctgaagaa atacaacctg cgatcccggt gtagtatagc aaagatacca tctgaagaat 10680 tatctatcaa agtaatttgg gacgtaaagg aagaaagtag gttaaaagat actgtcgctt 10740 acgcaaaaga tcctcgcttt tccaaacagc gtttgctacg aatgatagtt cctacttcta 10800 catgcacttc ttcttcctcc ggctcgctag atgattacaa agtctttaga taccgaaatg 10860 gaataccaga agggcctcaa gagattattc ctagtatttc atttcctctg gaaagcaaca 10920 tggattggat gaaggggatc gatttccaca agggctgcta tttgggtcaa gagctcactg 10980 tccgcaccta ctatactggg gtaacaagaa aaaggatttt cccatttatt attccgaact 11040 acgaagacaa tccatctcaa gttattgaac cttcggcgcc gctttcaatt gtcgcaaagc 11100 aaggagagcc ggtctctcgt cgatcgcctg gtaaaattat tgcaatttta ggaaaagtcg 11160 ggcttgcttt ggtccgtcta caatatctca aaagcgactt ggcatgtaat ggaataccta 11220 ttcagctgaa caccagtatc tggttagatg agttatcgtc tacgccaagt gaaaattcat 11280 aaattgaaaa agtttgcaga tttctcttct tttatttatt ctttctatca attattcatt 11340 tttattctac atctaactca aagctaattt gcgcattctc ccactcagtg taaatagtaa 11400 gaacacatgt caattgtatg tttatgttgt ggtactagta ctattaatcg caattcaatt 11460 aagtaagaaa tttcgtctag cctaaaccct ttttttttta cttgtaacgg aattcaatgg 11520 tggcaatcgt accttggcag cacatccgtc tacaataaaa atttgatcgt ttttttctta 11580 atctaaggaa ttgtatattt gaaggaattt tgtattacag caaaattcgc tgcggttcgt 11640 tataggggaa atgccgcaac caaagagagt agggtgaaac gtttcttttg cgtatacctg 11700 ccactgcact tttctacaag acttgattct cttgacgaaa aagggttaga ttaacttcct 11760 tttgttaatt aattaaaaac attcattaga attcatttga gtggattgct ggggtgtctc 11820 aggaaaagat tgataagcag tgcttcaaat aattcgccta cgcttgtcat tagagactta 11880 tctagtgttc tgaaaacagc gctttctttt atttggttta tttcgtttgc attaccttca 11940 gattaactta tcgcaaacag atttttgttg tatctcgcat ctcaaaaaat tcaggcttta 12000 ataatcgcac ttggacttcg tttcacttaa ccaaaaatgg ctcaagcgga ctttgtttcc 12060 cctacatcta ttgatgtaag tgagaaaaag gaagttgagt ttcataagaa ggttgatcat 12120 gtcgaaaacc ctcccctgtc tacggaaagt gcaaaactcg aggctgagga agttgctgct 12180 gaaaagctaa actctgagca tttgttggag aatgagtttg ctcccatcac cgatcctact 12240 catcgtcggg tttccaaaaa tcctgatggc gccgagcttt ttcaattcga agatgagcct 12300 tcatattact atgtggtcgc aacttattta acctatctgg tgcttatcat tatagggcat 12360 gttcgcgact ttttcggtaa aagatttcat aaggatgact ataagtatct caaagacaat 12420 gatggttatg ctccccttta caatcatttt gataacttct atgtacgtcg tcttcagcat 12480 cgtattaacg actgtttcag ccgacctacc atgggtgttc ccggtcgtgt cattcgtctc 12540 atgaatcgct attccactga tagcaatagt acttttaaac taactggtga tacatcttta 12600 gccttaaacg tttcttcata caactacctt ggttttgccc aaagtcatgg tccttgtgcc 12660 acgaaggttg aagaagcgat gcaaaaatat ggtttgtcta cgtgcagctc aaatgccatt 12720 tgtggtactt atgggttgca taaagaagtt gaagaattaa cggcaaattt tgttggtaaa 12780 cctgctgctt tggtcttttc tcaaggattt agcactaatg ctactgtttt ctccaccctt 12840 atgtgccccg gatc 12854 //