ID SPAC1F3 standard; DNA; FUN; 28294 BP. XX AC Z70690; XX SV Z70690.1 XX DT 06-APR-1996 (Rel. 47, Created) DT 01-FEB-2000 (Rel. 62, Last updated, Version 4) XX DE S.pombe chromosome I cosmid c1F3. XX KW 3'-5' exonuclease; coiled-coil; conserved hypothetical; HRDC domain; KW MAP kinase kinase family; mhk1; mitochondrial intermediate peptidase; pmk1; KW serine/threonine protein kinase; KW yeast 5.8S ribosomal RNA 3' end processing protein Rrp6; KW yeast positive regulators of exocytosis Sro77p. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-28294 RA Connor R., Churcher C.M., Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (02-APR-1996) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; Q10146; Q10146. DR GOA; Q10407; Q10407. DR GOA; Q10408; Q10408. DR GOA; Q10410; Q10410. DR GOA; Q10411; Q10411. DR GOA; Q10413; Q10413. DR GOA; Q10415; Q10415. DR SWISS-PROT; Q10146; YD81_SCHPO. DR SWISS-PROT; Q10148; YAT1_SCHPO. DR SWISS-PROT; Q10407; MKH1_SCHPO. DR SWISS-PROT; Q10408; YD83_SCHPO. DR SWISS-PROT; Q10409; YD84_SCHPO. DR SWISS-PROT; Q10410; YD85_SCHPO. DR SWISS-PROT; Q10411; SPOF_SCHPO. DR SWISS-PROT; Q10412; YD87_SCHPO. DR SWISS-PROT; Q10413; YD88_SCHPO. DR SWISS-PROT; Q10414; YD89_SCHPO. DR SWISS-PROT; Q10415; PMIP_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/yeast/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1F3 is overlapped at the 5' end by cosmid SPAC3H8, CC EM:Z69086 and at the 3' end cosmid SPAC1D4, EM:Z69239. XX FH Key Location/Qualifiers FH FT source 1..28294 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1F3" FT /map="IR" FT misc_feature 1..54 FT /note="nominal overlap with cosmid SPAC3H8, EM:Z69086 S. FT pombe chromosome 1" FT CDS 7..2073 FT /codon_start=1 FT /db_xref="GOA:Q10146" FT /db_xref="SWISS-PROT:Q10146" FT /label=SPAC1F3.01 FT /note="SPAC1F3.01, len:688, SIMILARITY:Saccharomyces FT cerevisiae, Q12149, Chromosome XV reading frame ORF FT YOR001W, (733 aa), fasta scores: opt: 1129, E(): 0, (35.3% FT identity in 660 aa)" FT /partial FT /gene="SPAC1F3.01" FT /gene="SPAC3H8.11" FT /product="similar to yeast 5.8S ribosomal RNA 3' end FT processing protein" FT /protein_id="CAA94619.1" FT /translation="DYSIDKAQGLLKKPAIETHASTSDVANKKPKKEKLPYKVIHAAHL FT TKPQLRFRVQPNNSREFVWSWKLTEKPHSLVPLEKIIAQVKLDPSLKNSLPHPYEPEIQ FT NSVYPPWVSEMSNPIDTGSVDETEPIWVSTESQLSDMLKELQNSKEIAVDLEHHDYRSF FT RGFVCLMQISNREKDWIVDTLELREELEALNVVFTNPNIIKVFHGATMDIIWLQRDFGL FT YVVNLFDTYYATKVLGFEGHGLAFLLQKYCDYDADKRYQMADWRIRPLPREMLKYAQSD FT THYLLYIWDHLRNELISKSAERKENLMQSVFNSSKQISLRKYELEPYDPIYGLGTDGWR FT NVLTKFGSSKIIGREALMIYRALHDWRDSVARKEDESVRYVLPNRLLIAIAASKPVEAA FT DVFSISKQLTPIARMYVEDIVKVVQEAEKLYNEQVDREKSQFKEVEKQNQPLAVFSESN FT TLGDYKVDSSVFEISKQNRSKLKTLLANGSAFWIEGQSQDDLRKARKERLFIVNQNIPF FT SLTLPCTQGHVESELNVKQSTVTEAANPSLNGEKKQEPIVIRDLGLNKQKRDSSKLNHK FT EPSNPIEERNEDIEPSEASTSVSKKRKQKKKKKNSGKLTIEAEHVSNDSPIINEAPFDY FT KNQKNFIADLDSDVGKNKFGKRGFNPLNKVSLPKRNTRELKKRKVSDGKSTSY" FT misc_feature 385..1008 FT /note="Pfam match to entry PF01612 3_5_exonuclease, 3'-5' FT exonuclease," FT misc_feature 1063..1305 FT /note="Pfam match to entry PF00570 HRDC, HRDC domain," FT CDS complement(2294..5644) FT /db_xref="GOA:Q10407" FT /db_xref="SWISS-PROT:Q10407" FT /label=mhk1 or pmk1 FT /note="SPAC1F3.02c, len:1116" FT /gene="SPAC1F3.02c" FT /gene="mhk1" FT /gene="pmk1" FT /product="serine/threonine-protein kinase mhk1" FT /protein_id="CAA94620.1" FT /translation="MAADIGSQSSGSLEERFEQSLHLQNVDKQDWSLNSVLQFLKLYKF FT NKEWEDVFIKSRIEMDLFINLADQSKAEEFAFKNKLSKESAIQLSSCIRKTLLAPSSTR FT VPSKNSSYETLTYSAKDSSDDVFTETNSGFRSSNQNSSLKSFQSVPDSNVNVFGGFGGS FT VVDNNELLSTGKNSHQTTSLNLEGSPINLHAYKGTVTSIINDDSRNINKKTLSKQPVSE FT HKEKQTSFLRRFRVPGFSRDKDKTKDCPSSNSNPFHLASSNVKTLDASLDQGEWVPRIH FT RLESQIGLISKKKSFVLATMDDMKFTVVDITNVQNATQLRKLIAKSMYLDISIDQFDLF FT LTEVGGAQYIEILDDRKLDIARLYSDEFGTIKFFVKPSQNEESGMDSDTYLSFGTKSSS FT TYKADDDSIYHRKEDFKKQPSYPVLTSDFEITDAGPNLSLSGHQPDNKYYKGFSSAPNL FT AVVPELPSRRFRGFEKIRGAKGEMATKILDATEAQSEKNKFTVCRPHKKVTLKMPLNSG FT SSAPQSPSSNTSASVLTRNFVAHRDPPPPPTETSSLRRKNTLTRRPSIRHARSSPYIDT FT GHNEASKFSHTSFDPKASSKSSNSLKESVEALSEIPFEDAPALDESDLSGDPFWAIQPK FT QSSSQVPKENHHNIQSKLSINTEAATDLKANELSSPKTPEYCRGDDRSISLSPLSYRLR FT KSKHIRESPPSSKVINSGNWEVRPSADDLYEDVDRFFPRYDLDKVLVVDQSRMVSSPSK FT VSIRPKMKSVRLLAREASEARKEIRHNARRNKSGNLLRRSSTKLWGSRIVELKPDTTIT FT SGSVVSQNATFKWMKGELIGNGTYGKVFLAMNINTGELIAVKQVEIPQTINGRHDQLRK FT DIVDSINAEISMIADLDHLNIVQYLGFEKTETDISIFLEYVSGGSIGRCLRNYGPFEEQ FT LVRFVSRQVLYGLSYLHSKGIIHRDLKADNLLIDFDGVCKISDFGISKHSDNVYDNDAN FT LSMQGSIFWMAPEVIHNDHQGYSAKVDVWSLGCVVLEMLAGRRPWSTDEAIQAMFKLGT FT EKKAPPIPSELVSQVSPEAIQFLNACFTVNADVRPTAEELLNHPFMKCDEEFNFKDTNL FT YDMLCKRKS" FT misc_feature complement(2363..3166) FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 283.77" FT misc_feature complement(2756..2794) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(3083..3154) FT /note="PS00107 Protein kinases ATP-binding region signature FT " FT LTR 6162..6511 FT /note="Tf1-type LTR" FT CDS join(6640..6741,6789..7218,7267..9172,9216..9792) FT /db_xref="GOA:Q10408" FT /db_xref="SWISS-PROT:Q10408" FT /label=SPAC1F3.03 FT /note="SPAC1F3.03, len:1004, LOW SIMILARITY:Saccharomyces FT cerevisiae, SNI2_YEAST, sni2 protein, (1010 aa), fasta FT scores: opt: 516, E():1.5e-25, (24.3% identity in 1016 aa)" FT /gene="SPAC1F3.03" FT /product="similar to yeast positive regulators of FT exocytosis Sro77p" FT /protein_id="CAA94621.1" FT /translation="MSFFKKKLSKGKEILSKSNLKTHTSSNASLSIDDLNRFGFSLNPV FT LWCLDHQQGLLAIVSSTNRIYIYGKQHVQSVIVPDCSTIVHIALCAAYLIVIDSRNTVL FT SYPLMKHRDLSKPAATYFLKQKVTCTVTDPTIDWVFFGMSDGSVVPWDVTRHCLGKFKV FT PNLYVPRHEEWRMMGYSYAPVPGKLSPVVSVQIHPKDLGVILIAYPDGVVLYSIRTDEV FT IRFYELEYAPGSTAAVLSPHNYRRPIVKGIEWSPWGDHFVSYYTDSTFAFWDVDQEYPV FT QVRNFVDSNIHTYTPMQRNPPKTELEPIRSMRWCCCEDPTVSFILMLGGLPKEAPVKGI FT SLFSYRNLPAKKDVETFAEFFANPNSQRFFPFIDIPPVRDMLVIPSSSPHYNGSHNPKN FT LLLLSEDNSLSLLDISTGNISNMSLSIPPSLCFLASDFRVIAFQTVTKKVWNQIEDTIS FT VNSHYSCLFGGSPSPGYLKKLDERNLLITSTGLSLSIWDISQGFMNPSLCVNLDFSSVM FT RKHLTPSAFITTASFSTYNPEFSCADSFGRVIVCKRKNHKENLPAQLANGIYRLDDTLV FT LEGTLHAQYYIDLKRGRVTLNQMSNIGFVCIGYQDGGITIIDMRGPHILCNTSISELGL FT ERRGKPDPDFLTSAEFVVMNPKGSPSSIYVVTGTYRGMTLLFRIDPSSSGRFSAYFESS FT RQLDIKNIYKICSLTQDGQIATATGSSLQSVGYPLPQEVFLVYIGDSGISVFNKINNQV FT GNLDWRKPVCCRAALVLSTVSKHMGSVVCVNSDLSVNWYSLPNLREERKMQLPLDIDKN FT RLKEGDILGNGDYIFPTLGAHELAFGCVLGSGRTLANLAPMMLITHNASHVPPRPSKSL FT WNWLLGEQSTSAEELDILLGGENRAESKVHTLETPKVISARPAESVKQPLTPVPSMTSQ FT SAQSYIPPRRQQQQKGFFAQINDHLAQRGNMLGGIENTMDDLEEMSAEWANEIKDSLAG FT TKKDLILSGLKSYIP" FT misc_feature 6742..6747 FT /note="splice donor sequence, gtaagt" FT misc_feature 6772..6788 FT /note="splice branch and acceptor sequence, ttaataacaaagatt FT ag" FT misc_feature 7219..7224 FT /note="splice donor sequence, gtacgt" FT misc_feature 7256..7266 FT /note="splice branch and acceptor sequence, ctaattttcag" FT misc_feature 9173..9178 FT /note="splice donor sequence, gtaagg" FT misc_feature 9200..9215 FT /note="splice branch and acceptor sequence, ctaactattccatta FT g" FT CDS join(complement(10785..10987),complement(9985..10648)) FT /db_xref="SWISS-PROT:Q10409" FT /label=SPAC1F3.04c FT /note="SPAC1F3.04c, len:288, SIMILARITY:Saccharomyces FT cerevisiae, YO06_YEAST, hypothetical 35.7 kd protein in FT dnl4-slg1 intergenic region., (313 aa), fasta scores: opt: FT 874, E():0, (50.4% identity in 246 aa)" FT /gene="SPAC1F3.04c" FT /product="conserved hypothetical protein" FT /protein_id="CAA94622.1" FT /translation="MGPRSSNRRSNAKDGFKGSNKASKFPLPLAMWDFGHCNPNACSGK FT RLERLGCVRNLRIGQKFRGVVITPNGKVPVSPADKEYFDNGGASVVECSWARIEEIPFS FT RIGGRCERLLPYLVASNPVNYGRPWRLNCAEALAACMYIVGYPNEARLLMDNFKWGHSF FT FEVNEELLDIYAQCHDAQDIQEKEKKYLEEMEASYQEQRNQTTDDIWSAGNLNHKPTLN FT TSSTHSNSEESRSPLHEPSEASLAHDEHSIPTDDNEETLTNLQANDVDEDEVWRKIVRM FT KVHSTDT" FT misc_feature complement(10649..10660) FT /note="splice branch and acceptor sequence, ttaacgctgcag" FT misc_feature complement(10779..10784) FT /note="splice donor sequence, gtaagt" FT CDS join(12068..12101,12171..12258,12314..12389,12548..13882) FT /db_xref="GOA:Q10410" FT /db_xref="SWISS-PROT:Q10410" FT /label=SPAC1F3.05 FT /note="SPAC1F3.05, len:510, SIMILARITY:Schizosaccharomyces FT pombe, P87157, hypothetical 59.5 kd protein c25h2.16c in FT chromosome ii., (533 aa), fasta scores: opt: 947, E():0, FT (37.0% identity in 533 aa)" FT /gene="SPAC1F3.05" FT /product="conserved hypothetical protein" FT /protein_id="CAA94623.1" FT /translation="MRSSQTLSKYIDKATDQFNLEPNLALNIEIADLINEKKGNTPREA FT ALLILKRVNSANPTVSYLALHLLDICVKNCGYPFHFQIASEEFLNGFVSRFPNHPISRM FT NKIQSKMLEMLEEWNYMLCKNNRHREDFSRIHDIRELMAFRGYKFPAVDEDSIAVMKPN FT NSLRSAQELAREDLEAHKAKLQELLRRGTPMDLAEANALMKVIAGYDEENTEDYSALAA FT ADLESIRSKALRVKQFLVNQTVSLEEGTLADAVESLKVYQTKIARILREENEDEYYVQK FT LLSLNDLLINVIEECSNSDLIHSGTNVVSSQPNVVESHVPPSSNDTKQESSLIDLMKLT FT EEPAVPSPSLPTNVPANQSLSMLSSLSNSMSSTSNGALNSPSYSQAAIPNTNSSLTSIL FT QSDSLMISTQLTSVQKSSGFASYSVQFSNCSLTWPVSEVVFQVAVVKSLKLQLLPHTGD FT AIIAPGKQNAAHEIMNITNIPADASDLRIRWRVQWIIGTDHRVEQGESHLPL" FT misc_feature 12102..12107 FT /note="splice donor sequence, gtgagt" FT misc_feature 12156..12170 FT /note="splice branch and acceptor sequence, ctgacaagtaattag FT " FT misc_feature join(12167..12258,12314..12389,12548..12787) FT /note="Match to PF00790 VHS, VHS domain Score 196.83" FT misc_feature 12259..12264 FT /note="splice donor sequence, gtacgt" FT misc_feature 12300..12313 FT /note="splice branch and acceptor sequence, ctgactttttcgcag FT " FT misc_feature 12390..12395 FT /note="splice donor sequence, gtaagt" FT misc_feature 12530..12547 FT /note="splice branch and acceptor sequence, ttaacataagtgctt FT tag" FT CDS complement(14226..20099) FT /db_xref="GOA:Q10411" FT /db_xref="SWISS-PROT:Q10411" FT /label=SPAC1F3.06c FT /note="SPAC1F3.06c, len:1957" FT /gene="SPAC1F3.06c" FT /product="hypothetical coiled-coil protein" FT /protein_id="CAA94624.1" FT /translation="MSNQSSSGSNTSDLDEESASSLVSSAASPFIDSDLETPRPNISRA FT STGQLAEDGDTSSQHEDSSEELKRQEVRGMRRHSDLSIDAKLGSSEGSTASSALPLTPR FT SPSNASWLLVRGGLLDSPILDINSVTQKSNLLNELKQVRSKLAALEHENGILSLQLSSS FT NKKDKNTSSVTTLTSEEDVSYFQKKLTNMESNFSAKQSEAYDLSRQLLTVTEKLDKKEK FT DYEKIKEDVSSIKASLAEEQASNKSLRGEQERLEKLLVSSNKTVSTLRQTENSLRAECK FT TLQEKLEKCAINEEDSKLLEELKHNVANYSDAIVHKDKLIEDLSTRISEFDNLKSERDT FT LSIKNEKLEKLLRNTIGSLKDSRTSNSQLEEEMVELKESNRTIHSQLTDAESKLSSFEQ FT ENKSLKGSIDEYQNNLSSKDKMVKQVSSQLEEARSSLAHATGKLAEINSERDFQNKKIK FT DFEKIEQDLRACLNSSSNELKEKSALIDKKDQELNNLREQIKEQKKVSESTQSSLQSLQ FT RDILNEKKKHEVYESQLNELKGELQTEISNSEHLSSQLSTLAAEKEAAVATNNELSESK FT NSLQTLCNAFQEKLAKSVMQLKENEQNFSSLDTSFKKLNESHQELENNHQTITKQLKDT FT SSKLQQLQLERANFEQKESTLSDENNDLRTKLLKLEESNKSLIKKQEDVDSLEKNIQTL FT KEDLRKSEEALRFSKLEAKNLREVIDNLKGKHETLEAQRNDLHSSLSDAKNTNAILSSE FT LTKSSEDVKRLTANVETLTQDSKAMKQSFTSLVNSYQSISNLYHELRDDHVNMQSQNNT FT LLESESKLKTDCENLTQQNMTLIDNVQKLMHKHVNQESKVSELKEVNGKLSLDLKNLRS FT SLNVAISDNDQILTQLAELSKNYDSLEQESAQLNSGLKSLEAEKQLLHTENEELHIRLD FT KLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMSQSQAITSVKSKLDETLSKSSKLE FT ADIEHLKNKVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAENDDLQSKL FT SVVSSEYENLLLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELEELTSKYGKL FT GEENAQIKDELLALRKKSKKQHDLCANFVDDLKEKSDALEQLTNEKNELIVSLEQSNSN FT NEALVEERSDLANRLSDMKKSLSDSDNVISVIRSDLVRVNDELDTLKKDKDSLSTQYSE FT VCQDRDDLLDSLKGCEESFNKYAVSLRELCTKSEIDVPVSEILDDNFVFNAGNFSELSR FT LTVLSLENYLDAFNQVNFKKMELDNRLTTTDAEFTKVVADLEKLQHEHDDWLIQRGDLE FT KALKDSEKNFLRKEAEMTENIHSLEEGKEETKKEIAELSSRLEDNQLATNKLKNQLDHL FT NQEIRLKEDVLKEKESLIISLEESLSNQRQKESSLLDAKNELEHMLDDTSRKNSSLMEK FT IESINSSLDDKSFELASAVEKLGALQKLHSESLSLMENIKSQLQEAKEKIQVDESTIQE FT LDHEITASKNNYEGKLNDKDSIIRDLSENIEQLNNLLAEEKSAVKRLSTEKESEILQFN FT SRLADLEYHKSQVESELGRSKLKLASTTEELQLAENERLSLTTRMLDLQNQVKDLSNIK FT DSLSEDLRTLRSLEDSVASLQKECKIKSNTVESLQDVLTSVQARNAELEDEVSRSVDKI FT RRRDDRCEHLSGKLKKLHSQLEEQHETFFRAEQQRMTQLGFLKETVKKQEKLLKKLNLR FT QEQLIPRSSILVYESYIRDIEKEIIVLQERLNGIELSQQLPKGYFGYFFKTNRVEMEVL FT DSFKQQVAKLQFLAGAEFIVKFKEDLEKCAAEEKEKQATFDNYSEKVENLGKSIEALYF FT ALNREISFRKSLALSKSAYHNLLVRDSPKFNPDSQITYSIPVTNTKQSLLRSAILCVIS FT LQRLRLLGQRHSFCEEVIENLSCV" FT CDS join(complement(21295..21637),complement(20352..21220)) FT /db_xref="SWISS-PROT:Q10412" FT /label=SPAC1F3.07c FT /note="SPAC1F3.07c, len:403" FT /gene="SPAC1F3.07c" FT /product="hypothetical protein" FT /protein_id="CAA94625.1" FT /translation="MNAESCSLILSYISSAPAGNLVLNCTATTNKQTLEANLKSAVYQR FT YPEFLEDWTNVCVHIIHSYFPKDADYWNVDKLYTSVNRITTLEQSKVVGKEIKNGFTFD FT AENSTASLENDLQPQFRSHALFMVGSAGPLFSSTARTSRLDSRLPDGGIIAKPVALLPT FT PSVANSQEYTLDKLSPPSTAKPPASVIEFNPSLAKLPTVKYLQSGPFSSIAPYKNSSSS FT VIPDSSFHSVACYRASSHYKEAPVEKSIDIDIIQNNLSLLEEDSWTSVPIQGELVELNK FT LLQHLQLLQNQRITSHNVLSDEERQISVQVQNLILKLAKDYDMSPEDFLMDDFTLSLTQ FT YGAFYRGTLPLSAQPLELPSQQLLRSQSNAALRSNSLSMNGSLSPSSTNVPLQSYRRTT FT KSRR" FT misc_feature complement(21221..21234) FT /note="splice branch and acceptor sequence, ctaatttagtcaag" FT misc_feature complement(21289..21294) FT /note="splice donor sequence, gtaagt" FT CDS complement(21944..22270) FT /db_xref="GOA:Q10413" FT /db_xref="SWISS-PROT:Q10413" FT /label=SPAC1F3.08c FT /note="SPAC1F3.08c, len:108" FT /gene="SPAC1F3.08c" FT /product="very hypothetical protein" FT /protein_id="CAA94626.1" FT /translation="MVIYCNWLELKGLLETNDFLYLMRCCYMYDTVSLVSNAPNIYSIP FT FFYDRICYDYKNILLKYELFIIYYYYYLLICLSPHFFPIKRIRPFHENPLHSFVYRIMI FT SSEA" FT CDS join(23733..23767,23865..24031,24145..24972,25030..25110, FT 25181..25755) FT /db_xref="SWISS-PROT:Q10414" FT /label=SPAC1F3.09 FT /note="SPAC1F3.09, len:561, LOW SIMILARITY:Caenorhabditis FT elegans., O16213, f17a9.3 protein., (509 aa), fasta scores: FT opt: 278, E():1.5e-10, (26.5% identity in 306 aa). FT NOTE:corresponding transcript SPD244 is framshifted w.r.t FT this sequence; it also does not use the two final predicted FT splice sites; however this prediction shows reasonable FT homology to yeast YGR093W in this region and hence has been FT kept; it is possible this locus displays alternative FT splicing, or SPD244 is incompletely spliced" FT /gene="SPAC1F3.09" FT /product="hypothetical protein" FT /protein_id="CAA94627.1" FT /translation="MIFYDKLKPADVLVIGSADGRVIEAIEYIADLHKQHGFKFAICLG FT NLFSHKRTTSADVVKLKNEKVKVPIPVYFGVGTAGLPESIISHMAMYGPEVAPNLFCMG FT ICGFMKTFYKFTIAQLGGSYNEEKYYQPPEKFEQSLNEKCFHRSDVQKLSKRCDILFSS FT EWPEDVQENSTLPERKLPKGCMPLAALAANCMPQYFFVPGPVYYEREPYKNSAAINVNT FT GTVTHFVALAPFKNSKNEKFSYAFTLYPLTTEYMQPAPPNCTASPFEHRPIPLKRASED FT QIIPQQTNKFHKSKSSTALFKSKKDSSSSLNKMHKSESHSALNNLHKSESGTSLNNRRS FT KVGPGSCFFCLSNPNVALHLIVAIGNEAYMALPKGPLTTTASNTPALASSGHVLIIPIA FT HASALSTLSDTSYEKTLNEMNRFRKAVTDMYNACDSDALVYEISRANGVHLHWQMIPIP FT KISSHRIESVFLEMAKEAGYDFEERDVEPHELNYFRVFLPSGKILIHRLQLRERFDLQF FT GRRAAAKILGLEDRVDWRKCVQTEDEEKAESEAFKMCFKPYDFT" FT misc_feature 23768..23773 FT /note="splice donor sequence, gtaagt" FT misc_feature 23846..23864 FT /note="splice branch and acceptor sequence, ctaacatagattcga FT atag" FT misc_feature 24032..24037 FT /note="splice donor sequence, gtatga" FT misc_feature 24129..24144 FT /note="splice branch and acceptor sequence, ctaacctgagctgta FT g" FT misc_feature 24973..24978 FT /note="splice donor sequence, gtgagt" FT misc_feature 25013..25029 FT /note="splice branch and acceptor sequence, ctaacttcttttctc FT ag" FT misc_feature 25111..25116 FT /note="splice donor sequence, gtacgt" FT misc_feature 25169..25180 FT /note="splice branch and acceptor sequence, ctaacgactcag" FT CDS complement(25819..28107) FT /db_xref="GOA:Q10415" FT /db_xref="SWISS-PROT:Q10415" FT /label=SPAC1F3.10c FT /note="SPAC1F3.10c, len:762, SIMILARITY:Schizophyllum FT commune, PMIP_SCHCO, mitochondrial intermediate peptidase FT precursor, (775 aa), fasta scores: opt: 1569, E():0, (37.1% FT identity in 779 aa)" FT /gene="SPAC1F3.10c" FT /product="putative mitochondrial intermediate peptidase FT precursor" FT /protein_id="CAA94628.1" FT /translation="MQVRTLLTLGKKKVIGNRQCILSLYRKYSNVQSRKAEDQLLRQIF FT DDQNIAVNQITKRNGIQGVGLFRNHFLSDKDTGFLRLAETASEKCKAVIEDLLLEDTED FT GSIVVSKFDRISNLLCSVIDLFEFVRCAHPDKMVVMKAEEAYSYLFELMNTLNTHQGLY FT EKLKCSLQQTPTLKDTDPEAYTVGRVFLQDFEKSGVNLESSKRNSFVKKSSESATLGRA FT FFNNSMNRPQRYLTISKQRLAGSDPYFVRSLSKNDKNFIMIPTVGYEGTQALISVANPD FT VRKEIYMEGHKGTVEEVELLNSYLRSKAEVAKLVGKSSFADLQLIDKMANAPKHVVEFL FT ENLSLKNSSVLKKILNNLALMKKKELNLNFLPSFDVWDREYYTARYKQSLINQKPSLNP FT SITNYRRFFSVGTVIQGLSRLFSSLYGLRFVPADISPGEVWHPDVNKVNVYNENDHVMG FT VIYFDLFARTGKTDGAAHFTIRSSRELDLTSFDDSISLGFDDATNIRVKDNKRYQIPVI FT SLLCNFVRSSGMDPTFLDLWDVKTLFHEMGHAMHSILGHTKYQNLAGTRCATDFVELPS FT IIMEFFMSNPAVLPLYARYEGTEIPLPVQVLNHHNMVENSSAPLDLQSQICMAMVDQLF FT HSKVVLDPSFNSIDEVTNVTRKFSGFESAPPAAWYLQFSHLYGYSATYYSYIFDTVLAS FT LIFSKLFAGNPLSREAGEKFRKAILRWGGSRSPWECVAEALEQPILATGGEEAMRRIGS FT EGIKATSTF" FT misc_feature complement(25858..27786) FT /note="Pfam match to entry PF01432 Peptidase_M3, Peptidase FT family M3," FT misc_feature complement(26458..26487) FT /note="PS00142 Neutral zinc metallopeptidases, zinc-binding FT region signature" FT misc_feature 28108..28294 FT /note="nominal overlap with cosmid SPAC1D4, EM:Z69239 S. FT pombe chromosome 1" FT CDS 28114..28294 FT /db_xref="SWISS-PROT:Q10148" FT /label=SPAC1F3.11 FT /note="SPAC1F3.11, len:60" FT /partial FT /gene="SPAC1F3.11" FT /gene="SPAC1D4.01" FT /product="hypothetical protein" FT /protein_id="CAA94629.1" FT /translation="MRQIFGTCTGYMNGIYFQEGLLEIPTTKSIRMNSIHIKKKSNRSF FT RRRKVFGNEKEFDLE" XX SQ Sequence 28294 BP; 8622 A; 5308 C; 5168 G; 9196 T; 0 other; atataggact attctatcga taaagctcaa ggacttttaa aaaagccagc gatcgaaacc 60 catgcgtcga caagcgatgt tgccaataaa aaaccaaaga aagaaaagtt gccctacaag 120 gttattcacg cagctcatct tactaagcct caattaaggt ttcgagtaca gcctaataat 180 tccagggagt ttgtgtggtc ttggaagtta actgaaaaac cacattcgtt agtaccgctc 240 gaaaagatta tcgctcaagt caaattggac cctagtctca aaaactcgtt accacatcca 300 tatgaaccag aaatacaaaa tagcgtatat cctccatggg tttcagaaat gtctaatccc 360 atcgatactg gctctgtcga cgaaacagaa cctatctggg ttagtactga aagtcagtta 420 tcggatatgc taaaagaatt acaaaacagc aaagaaatag ccgttgatct tgaacaccat 480 gattacagat catttagagg gttcgtctgt ctaatgcaaa ttagtaatag agaaaaagat 540 tggattgttg acaccttgga actccgcgaa gagcttgaag ctttgaatgt tgtttttact 600 aatccaaata tcattaaagt ttttcatggt gcaactatgg atatcatttg gctgcaaaga 660 gatttcgggc tttacgttgt aaacttattt gatacatact atgctactaa agttttagga 720 tttgagggtc atggtctggc ttttctgtta caaaagtatt gtgattatga tgcagataaa 780 agataccaaa tggctgattg gagaatccgt cctttgcctc gggaaatgtt aaaatatgct 840 caatctgata cgcattattt gttatatatt tgggatcatt tacgaaatga actcatatca 900 aaatcagctg aaagaaaaga aaatcttatg caatcagtgt tcaattccag taaacaaata 960 tctcttagaa agtatgaact tgagccttat gatcctattt atggacttgg tactgatggc 1020 tggagaaatg tacttactaa gtttggctct tctaaaataa ttggacggga agctttgatg 1080 atttatcgag cactgcacga ttggagagat tccgtagccc gaaaagaaga tgaaagtgtt 1140 cgctatgtgt tgccaaatcg tttacttatt gcgattgccg ccagtaaacc ggttgaagcg 1200 gctgatgtgt tttcaatttc taagcaattg acaccaattg ctcgcatgta tgttgaagat 1260 atcgttaaag tcgttcaaga agccgaaaag ttgtataatg agcaagtaga tcgtgagaaa 1320 tcccaattta aagaagttga gaagcaaaat caaccgctag cagttttttc cgaatcgaat 1380 actttgggtg attacaaagt tgactccagt gttttcgaga tttctaaaca aaatagaagt 1440 aaactaaaga ctttgctggc aaatggatct gcgttttgga ttgagggaca gtcgcaagat 1500 gatttacgga aagctcgtaa agagagactc tttatagtga accagaatat tcctttttca 1560 ttaactcttc cttgtactca agggcatgtt gaatccgaat tgaatgtaaa gcagtccact 1620 gtaactgaag ctgcaaaccc gagtctgaat ggagagaaga aacaagagcc tatagtcatt 1680 agggatttag ggctgaacaa gcaaaaaagg gattcttcta agcttaatca taaagaaccc 1740 tcaaacccca tagaggagcg aaatgaagat attgaacctt cggaagcttc aacttcagtg 1800 tcaaaaaaac ggaagcaaaa gaagaaaaag aagaacagcg gaaaacttac tattgaagcc 1860 gaacatgttt ctaatgacag tccaattatc aatgaagcac cttttgatta taaaaatcaa 1920 aagaatttta ttgctgactt agactctgat gtaggaaaaa ataaatttgg gaaacggggt 1980 tttaatcctc ttaacaaggt aagtttacca aagcgaaata ctagggaact caaaaaaagg 2040 aaggtttcag acgggaagag tacatcttat taatatcagt tttaatttta aataaacgaa 2100 acaattttga caaaatgaaa atttactttt aaatacattg tagaaattga aaatgatcat 2160 gtatgtttgt ttgtataata atgtaataat tttcaaaatt aatttcaata ttaaataaat 2220 agctataaga agaaattgag aatgcatgcc cctgcgagga aacgctaagt aataaataat 2280 aattgcgacc aatttagctc tttcttttac aaagcatgtc gtaaagattc gtgtccttaa 2340 agttgaattc ttcgtcacat ttcataaacg ggtgatttaa taattcctct gcggttggcc 2400 ttacatcagc attcacagta aagcatgcat tcaaaaattg aatcgcttcg ggtgatacct 2460 gagacaccaa ttcactagga ataggaggcg cctttttctc ggtacctaac ttgaacatag 2520 cttggatagc ctcatctgta gaccacggtc tacgaccagc taacatttcc aacactacac 2580 atcccaagga ccagacgtcg accttagcac tatatccttg atgatcatta tgaattactt 2640 caggtgccat ccaaaagatg gatccttgca tggacaggtt tgcgtcattg tcatacacat 2700 tatcactatg cttagatatt ccaaagtctg aaattttgca aactccatca aaatcaatga 2760 gcaaattgtc agcctttaaa tctcgatgta taataccttt agaatgtaag taagacaacc 2820 cgtagagcac ctggcgtgat acaaaacgga ccagttgctc ttcgaaagga ccataattcc 2880 gcaaacatcg accaattgaa ccacctgaaa catattccag gaatatactt atatccgttt 2940 ccgtcttttc gaaacccaga tattgcacta tatttaagtg atccaaatcg gcaatcatag 3000 aaatttctgc attaatggaa tccacgatat ctttgcgtaa ttggtcatga cggccattaa 3060 tagtttgtgg tatttcaact tgctttactg caatcaattc acccgtatta atgttcatag 3120 ccaaaaatac cttaccataa gtaccatttc caatcaattc tcctttcatc catttgaacg 3180 tggcattttg tgaaacaact gatccagaag ttatagtagt atctggtttt agttctacaa 3240 tcctagagcc ccaaagtttc gtacttgatc gacgtagaag atttccagat ttattgcgtc 3300 tcgcgttatg tcgtatttct ttccgagctt cagatgcttc gcgggctaat aatcgtacag 3360 acttcatttt cggacgtatc gatacctttg aaggggaaga aaccatgcgg ctttggtcca 3420 ctacaagtac tttatccaaa tcataacggg gaaaaaatcg atcaacatcc tcataaagat 3480 catcagcaga tggacgaact tcccagttac cagaattgat aacctttgaa gacggtgggg 3540 attcacgaat atgtttggac tttcttaaac gataagataa cggtgataaa ctaatggatc 3600 tgtcatcacc tctacagtat tcaggagttt taggcgaaga tagttcattt gctttcaaat 3660 ccgtagcagc ctctgtgtta atggaaagtt tggattgaat gttgtgatga ttttctttag 3720 gtacttggga ggaagattgt ttgggctgta tagcccaaaa gggatcccca gaaagatccg 3780 attcgtctag tgcaggcgca tcttcaaaag gtatttctga taaagcttcc acactttcct 3840 ttaatgaatt agaagattta ctagatgctt tggggtcaaa agacgtatgt gaaaatttgc 3900 tagcttcgtt atgtccggta tcaatgtaag gagaggaccg agcgtgacga atacttggtc 3960 tacgagtcaa tgtatttttt cgacgtaaac tagatgtctc tgtgggtggg ggtggaggat 4020 ctctatgtgc cacaaaattt ctagttaaaa cagaagcaga agtattagat gaaggacttt 4080 ggggagcgga agagccggaa ttaagtggca ttttcaatgt gaccttcttg tgaggtctac 4140 aaacggtaaa tttgtttttt tcactttggg cttcagtggc atccaaaatt tttgtagcca 4200 tttctccttt agcaccacgg attttttcaa accctcgaaa acgtcgagat ggtaattctg 4260 gaacaactgc caaattcggt gccgaactaa aacctttgta gtatttatta tcaggttgat 4320 gccctgataa tgataaatta ggtcctgcat cagtaatttc aaaatccgaa gtaagcacag 4380 ggtaacttgg ttgcttttta aaatcttcct tgcgatgata tattgagtca tcatcagctt 4440 tataagttga acttgatttt gtgccaaaag ataaataagt atcactatcc atacccgatt 4500 cttcattttg tgatggcttt acgaaaaatt taatagttcc aaattcatca gaataaagcc 4560 ttgcaatatc aagctttcta tcatctaata tttctatgta ttgagccccg ccgacttccg 4620 tgagaaacaa atcaaactgg tcaattgaaa tgtctaaata catactctta gctattagct 4680 tacgtagctg agtagcattt tggacgttgg taatatccac tactgtgaat ttcatatcat 4740 ccatagtagc aagaacaaat gacttctttt tggatattaa accaatttga ctttctaaac 4800 gatgaatacg aggtacccac tcaccttgat ccaaagacgc gtctaatgtt ttcacatttg 4860 aagaagctaa atggaatggg ttcgaatttg aagaagggca atctttagtt ttatccttgt 4920 cacgagaaaa cccaggtacc cggaaacgac ggagaaagct agtttgtttt tctttatgtt 4980 cggatacagg ttgtttcgac aatgtttttt tattaatgtt tctgctgtca tcgttaatta 5040 ttgaagtgac agttcctttg taagcgtgta agtttatagg agagccttcc aaatttaaag 5100 aggttgtttg atgggagttt tttcctgtgc tcaatagctc attgttgtcg actactgatc 5160 caccgaagcc accaaacacg ttcacattgc tatcaggaac actctgaaag cttttgaggg 5220 acgaattttg atttgaagag cggaaaccag agttagtttc tgtaaaaacg tcatccgaac 5280 tatctttggc gctgtaagtt aatgtttcgt aagacgagtt tttgctaggt acgcgagtcg 5340 aagaaggtgc taaaagtgtt ttgcgaatac agctactcaa ttggatggca gactccttgc 5400 tcaatttatt tttaaaggcg aattcctcgg cttttgattg atcggccaaa ttgataaata 5460 aatccatttc gattcgactt ttaataaaaa cgtcttccca ttctttgtta aatttgtata 5520 gttttaaaaa ctgaagtaca ctgttaagtg accaatcttg cttatcgaca ttctgaagat 5580 gaagagactg ttcaaaccgt tcttccaaag agcctgatga ctgcgatccg atatcggcag 5640 ccatataccc agaacagtat tagttacttt gaaaagaatt caagataaaa aacctttttt 5700 ttgtcaaacg aattggagat tgctgcttaa gtagtttatg attaaaaaaa ttaagattcg 5760 gctgaaacga gtgaactaat ttgcaaaaga cagacttggg atgttagtaa tagcccaatt 5820 tcttgcaggt aaataaaata ttaagaaagg agagaaatgt tgaatcacta gtactcaggg 5880 tttaaagata ttgcaaaaag acttcccatg tgttttgaca tgcagcccgt atgataccgc 5940 caattccaca gaagcctgtt agaaaataat agagaattaa aaatagatac tttatcaatg 6000 taaaactgat atttcgattc tataaacctt cacgggtaaa ccaagcaatc tccagcttgg 6060 tgtctggctt taggcccgct caaaatcgct tgcggtttga ctagtgaatg atgcaaagtc 6120 gaattcagtg ctataaggat aaaattagaa gtctcattat ttgtcagcaa tactacatta 6180 cgctatgata cactacgttg tgtatcacta tatgtcatat gttggaatac tagctaagat 6240 ccgtttattg ataatcacgg gtaactatcc atctatatac tagttaccag ttgataacaa 6300 ctatttagaa atattataaa tagcgttaca actgaacctc gttcctcagt tcagttatga 6360 gctatattag tgataggtaa cattataaca cagttaatac aatactcagt tgctactcat 6420 acaacctgtt tattgtaata taataggtta caaggaaaac tcaccgcagt ttacgtatcc 6480 ttaaatcaga taccaaactg cgtagcttac attattattg gtttaacggc acaagacgtt 6540 atccaaaaat agcgttctct aacacgagtt gagcgtgagt ttgtatatgc tacgagggta 6600 taacatgatt agtatattta taccaagaat tgggaaaata tgagcttttt taaaaaaaag 6660 ctaagtaagg gaaaagaaat tttatccaaa tccaatttga agacccatac gtcttcaaat 6720 gcttcactat cgatagacga cgtaagtagg gaagcaatgc ttgttgaatg tttaataaca 6780 aagattagtt gaatcgattt gggttttcct taaatccagt attatggtgt ttagaccatc 6840 aacaaggctt actagctatt gtatctagta ctaatcggat atacatttac ggtaaacagc 6900 atgtccagag tgtgatagtt ccagactgtt caaccattgt ccatatagcc ctttgtgcgg 6960 cgtatttgat tgtaattgac tctcgaaata cggtcttaag ctatcccttg atgaaacatc 7020 gtgacctttc aaaaccagct gccacttact ttctcaagca aaaagttaca tgtaccgtaa 7080 cggatcctac tattgattgg gttttttttg gaatgagtga tggctccgtt gtgccatggg 7140 atgttactag acattgcctt ggaaaattca aagttccaaa tttgtatgtc ccaagacacg 7200 aggaatggcg aatgatgggt acgttgaggt cattgttgtt tatttgaatt tattactaat 7260 tttcaggcta ctcttatgca ccagttcctg gaaagctatc cccagttgta agcgttcaga 7320 ttcacccgaa ggatctcggt gtgattttga ttgcatatcc ggatggcgtt gttttgtact 7380 caataaggac tgacgaagtt atacgctttt atgaattgga gtatgcacca ggtagtacag 7440 ctgcagtttt atcaccccat aattatcgaa gacctatagt caaagggata gagtggagtc 7500 cttggggtga tcactttgtt agttactata ctgattcgac ttttgcattc tgggatgtgg 7560 atcaagaata tcctgtacaa gtccgaaatt ttgtcgattc aaacatacac acgtataccc 7620 ccatgcagag aaatcctcct aagacggagc ttgagcccat taggtctatg aggtggtgtt 7680 gttgtgaaga cccaacagtt tcatttattt tgatgttagg tggtttgccg aaagaagcac 7740 cggtaaaggg aatttcattg ttcagttatc gaaatctccc tgccaaaaag gatgttgaaa 7800 catttgcgga atttttcgca aatccaaact cacaacgctt ttttcctttt attgacatcc 7860 cccctgtacg tgatatgctg gtgattcctt ctagctcacc acattacaat ggatctcata 7920 atcccaagaa tcttctcctt ctttcggaag acaactcgtt atcgctgctc gacatttcta 7980 ctggaaatat ttcaaacatg agcctttcta ttcccccctc tttatgcttc cttgcttcag 8040 attttcgagt tatagcattt caaactgtaa caaaaaaagt ttggaatcaa attgaagata 8100 ctatttccgt taattcacat tactcctgtc tttttggcgg atctcctagt cccggctatc 8160 ttaagaaatt agatgagcgt aatctactta taacatcgac tggtcttagt ttatcgattt 8220 gggatatatc tcagggtttt atgaatccat ctctctgcgt aaatttggat ttctcttctg 8280 taatgcgaaa gcatctcacg ccttcagctt ttataactac tgcctctttt tccacttata 8340 atccagaatt cagttgtgct gatagttttg ggcgtgtcat tgtttgcaaa aggaaaaatc 8400 ataaagaaaa tttaccagct cagctcgcta acggaatata tcgtttggac gataccttag 8460 ttctagaggg aacattacat gctcaatatt atattgatct taaacgagga agagtaacat 8520 tgaaccaaat gagcaatatt ggttttgttt gtataggata tcaggatggt ggaattacaa 8580 tcatcgacat gcgtggcccc catatactgt gtaacaccag catctcggag cttggattag 8640 agagaagagg aaaacctgat cccgattttc ttacgagtgc cgagtttgtc gttatgaacc 8700 ctaaaggaag cccttcctca atctacgtag tcacaggaac atatagaggg atgacacttt 8760 tattccgtat agacccttcc tcttcagggc gcttttctgc ttattttgaa tcatctcgac 8820 aattagatat taagaacatt tataaaatat gctctttaac tcaagatggc cagatcgcga 8880 cagccactgg atcctcatta caaagcgttg gatatccctt accacaggaa gttttcctcg 8940 tgtatattgg cgattcagga atttctgttt ttaataaaat taataatcaa gtgggtaacc 9000 tggattggag aaaacctgtt tgttgtcgag cagctcttgt gctttctact gtttccaaac 9060 acatgggttc cgtagtttgc gtaaattctg atctttcggt gaattggtat tctctcccaa 9120 accttcgtga ggaacgtaaa atgcaacttc cattggatat tgataaaaat aggtaaggtg 9180 tttacttgaa atgaatttgc taactattcc attaggctca aagaaggtga tattctaggc 9240 aatggggatt atattttccc aacgttagga gcacatgaat tagcctttgg ctgtgtttta 9300 ggaagtggga gaacattggc gaatttggca cccatgatgc ttattactca caatgcttcc 9360 catgtaccgc caagacctag taaatccttg tggaattggt tactgggcga acagtctaca 9420 tctgctgaag agctagatat cttactcgga ggtgaaaaca gggctgaaag taaagtgcat 9480 actttagaga ctcctaaagt tatttcagct cgcccagcag aatcagttaa gcaaccactg 9540 accccggttc cttccatgac ttctcagtct gctcaaagtt atatccctcc aagaaggcaa 9600 caacaacaga aaggattctt cgctcaaata aacgaccatt tagcccaacg ggggaatatg 9660 ttaggaggaa ttgaaaatac tatggacgat ttagaagaga tgagcgctga atgggcaaac 9720 gaaattaagg actctttggc tggaacgaag aaagatttga ttctttcagg cttaaaaagc 9780 tatatacctt agaaagttat attttttttt acttgcattt atcaggttat gattgtttat 9840 gaaacttatt gaaagcttac catatttatt aattttgcat ctctctatac aatattacct 9900 tacatggata tgtaaagcac aaaaaacagg tgataaataa tagacaaact ataaattata 9960 taaaaatcca aaagtatata tcttttaggt atcagtagaa tgaactttca ttctcacgat 10020 ttttcgccag acttcatctt catccacatc gttggcttgc agattagtta gagtctcttc 10080 attatcatct gttggaatag agtgttcgtc atgagccaat gaagcttcgg acggttcgtg 10140 taatggtgac cgagattctt cagagtttga atgtgttgaa ctggtgttta atgttggttt 10200 gtgatttaaa tttccagctg accaaatgtc gtcagtagtt tgatttcttt gttcttggta 10260 agaagcttcc atttcctcca agtatttttt ttctttttct tgaatatctt gagcatcatg 10320 acattgagca taaatatcga gaagttcttc gtttacctca aaaaaagaat gtccccattt 10380 gaaattatcc attaaaagtc tcgcctcatt aggatatccg acaatataca tgcaagctgc 10440 cagagcttca gcacaattta atcgccaagg cctaccatag ttaactggat tggaggccac 10500 taaatatgga agcaaccgct cacagcgacc accaattcta gaaaaaggga tttcctctat 10560 gcgagcccaa gagcattcaa ctacactagc acctccatta tcaaagtact ccttatcggc 10620 tggagaaaca ggaacttttc cgtttggtct gcagcgttaa aatctgatac atagcaaaat 10680 ggtaaaaaaa tattaataat tagtcttagt gcccttgcgc tgtatacagc aaacattcga 10740 caagagttta agatcgggtt tctttctaac ggttctcaac ttacgttatt acaactcctc 10800 gaaacttctg tccaattcta aggtttcgta cgcatcctag acgctctaat cgtttaccag 10860 aacaggcatt tggattacaa tgtccaaaat cccacattgc taagggtaat ggaaatttgg 10920 atgccttgtt tgaacccttg aagccatctt tggcattaga acgacgatta gaactccttg 10980 ggcccatatc caaatatcga tgttgaaaag tgacacgctg tttgatgtag gaaatccgcc 11040 atatttggtg tgggtgttgt tatcaatcaa taatgcactg taccaatgcc gtgttaaaag 11100 taatcatctt cagtagcaat cgagtattaa gatgagagga aatctttatc tatatacaat 11160 tcgactactt aatcaattga ccgtccctcc ttcttttcag aaaaatattt ccttacattc 11220 attaaagata tgctattgaa aagtggatat tgcccaaaag tggttaatgt tctcactctt 11280 gagcgagaca atgcaatgac attagttttt tgcatttctt ggcaaatcca ggaaaaagcc 11340 tcgcggtaat ataagaatgg tcaattctcg taaaatgacc ttgtatggct gttaatactt 11400 tcatagttgt tcaaatagaa ctgttacaca aaactcgttt acacacaatg tattttcctc 11460 atgctttttc aacgatatac aattgtacaa ttgttctcct cgatccattt taaaaatttt 11520 gatacaaaat gaatagtgaa agtaatagca gagctacgtt ttcttgtcag tgtttaatta 11580 tggaacgtaa caacagtgtt agtttcattc ttcttacact tatcagtttc tgtgctcgat 11640 agtaaattgt ttcattcatg taaaaataat taaattcaat tggattttaa ttttcaattc 11700 gacactagct acagcaataa actgcggatc aaaaatatgg catgtagcat atatttgaag 11760 aattttagca agttttggga acttgttctt tacataaagc ttttcagctg aaccagatat 11820 aaccgggttc ttatggtggt tttaatcttt actctactat cgcatacctt atttgactta 11880 gaactcgttt ggtctcttgt tggtaaacca agcctcccaa cttccttgac tgaagagtat 11940 acctcagact tttgcacaat tttgtttttg gattttttct ttttgtttta attttattgg 12000 ctcttcaaat ctgcgaatct gccttctgtt ttgtttttag atctagaaaa atttactact 12060 tatcaccatg cgctctagcc agactttatc aaagtatatt ggtgagtatt cttttgtgac 12120 gctatatttt actgttaaga tgggaatatg aatcgctgac aagtaattag acaaagctac 12180 cgatcaattc aatttggagc caaatttggc cttgaatata gagatagcgg accttataaa 12240 tgaaaagaaa ggaaatacgt acgtgaatta aggatttaat tcctacaatt gctttgttgc 12300 tgacttttcg cagcccacgt gaagcagctt tattgatttt aaagcgtgtc aacagtgcaa 12360 atcccacagt ttcatatctg gctttacatg taagtatatt cctctagcct ttgaggagaa 12420 tggttggtac ccatcagttt acgaatctct cctttatgtg catggtcaag cgtttattgt 12480 tcaccatggc gagtccagag tactttacgc tttcttgtga gatatttggt taacataagt 12540 gctttagttg ctcgatattt gtgtaaagaa ctgcggttat ccatttcact ttcagatcgc 12600 atcagaagag tttttaaatg gattcgtttc acgattccca aaccatccca tctcccgaat 12660 gaataaaatt caatctaaaa tgctagaaat gctagaagag tggaattaca tgctttgtaa 12720 aaacaatcgc catcgtgaag atttttctcg cattcacgac attcgggagc ttatggcttt 12780 tcgtggttac aagtttcctg cggtagacga agattccatt gctgtcatga agcctaataa 12840 tagtcttcgt tctgcacaag aattagcacg tgaagattta gaagctcaca aagctaaatt 12900 gcaagaattg cttcgacgag ggacccccat ggatttggct gaagccaatg ctcttatgaa 12960 agtaatagct ggctatgatg aagagaatac tgaagattac tctgccttgg ctgctgccga 13020 ccttgaatcg attagatcaa aagcacttcg ggtaaagcaa tttttggtta atcaaactgt 13080 atctttagaa gaaggcacgt tggcggatgc cgttgaatct ttaaaggttt accaaacgaa 13140 aatagcaaga attcttcgag aggaaaatga agatgaatac tatgtgcaga aacttctttc 13200 gctgaatgac ctacttatta acgtcattga agaatgttcc aactcagact taatacattc 13260 cggtacaaat gtagtttcct cccaaccgaa tgtggttgaa tctcacgtac ctccttcttc 13320 taatgacacg aaacaagaat cttcgttaat tgatttgatg aagcttactg aggaacctgc 13380 agtcccgtcc ccatcacttc caaccaatgt accagccaac caatctctgt caatgttatc 13440 atccctttct aactctatgt cgtctacgtc gaatggagct ttgaattcac cttcttatag 13500 tcaagcagca atccccaaca ctaattcatc tttgacatct attcttcaat ctgattcatt 13560 aatgatttct actcaattaa cttcggttca aaaaagctct ggctttgctt catactccgt 13620 tcagttctct aattgctccc ttacctggcc agtgtccgaa gtagtcttcc aggtcgcggt 13680 tgtgaaatct ctcaagttac agctacttcc tcatactggg gatgcaatta ttgcccccgg 13740 aaaacagaat gctgcacacg agattatgaa tattaccaac atacccgccg atgcctctga 13800 tttacgaatt cgttggagag ttcagtggat catcggtaca gatcatcgtg tagaacaagg 13860 cgaatcgcat cttccgctgt aattctacgt gcgttttctt ccatttgctc aactagatga 13920 aggaatataa aaaaagtgaa aacgtcagtt gatattacag gttttattat ttaattaatg 13980 tgagcctctg cgatttgata aattaaacta taaactacga taaagcgaac tttccttatt 14040 tttagaattc tttccgcaat accgatttta aatttttata atacaaatgc cttaaccaaa 14100 accattttat tatatctctc agtcaacatt atatgcttca tagtaatgaa aaataaattt 14160 aaaatttatt ttttatcgaa gcaaacctta aaatagcctc aatcatgtag ttgttagtaa 14220 atcatttaaa cacaagagag gttctcgata acctcttcac aaaaagaatg tctttgacct 14280 aataatctca aacgttgcag tgatatgaca cataatattg cagaacgtaa caatgactgc 14340 ttggtattgg taaccggtat actataagta atttgggaat ctgggttaaa cttgggagaa 14400 tctcgaacca aaagattgtg atatgctgat ttagacaacg ctaaagactt tcggaaacta 14460 atttctcgat ttagtgcaaa atacaaagct tcaatcgatt tcccaagatt ttcaaccttc 14520 tcagaataat tgtcaaatgt agcttgtttt tccttttctt ctgcagcgca tttttcaaga 14580 tcctctttaa atttgacaat gaattccgca cccgcaagga actgtaattt agcgacttgt 14640 tgtttgaaac tatccaacac ttccatttcg acgcgattag ttttgaagaa atacccaaag 14700 tagcccttcg gaagttgttg cgaaagctca atgccattta gacgttcttg taagactata 14760 atttcttttt caatgtcacg aatatacgat tcgtaaacta aaattgaaga gcgaggaatt 14820 aactgttctt gccttaagtt tagttttttc aaaagcttct cttgcttttt cactgtttct 14880 ttgagaaacc ctaattgtgt catacgctgc tgttcagctc taaagaaagt ttcatgctgt 14940 tcctctaact gagaatgcag ttttttaagt tttccactta aatgctcaca tcgatcatcc 15000 cttcttctta ttttatccac tgaacgagaa acttcatctt ccaattcggc gttacgggct 15060 tgtacgcttg ttaatacatc ttgcaatgat tcaaccgtat tagattttat cttgcattct 15120 ttttgtaaac ttgctacaga atcttctaac gatcgtaacg ttcttagatc ctcgcttaga 15180 ctgtctttta tattagaaag gtctttgact tggttttgaa gatctaacat tcgggtggtt 15240 aaggataatc gttcgttttc agccaattgc aattcttccg ttgttgaagc cagcttcaat 15300 ttactacgac ctaattctga ctcaacttga gatttatggt actccaaatc tgccaagcgg 15360 ctgttgaact gcaaaatttc tgattctttt tcggtagaca gcctttttac agcagacttt 15420 tcctctgcaa gcaagttatt caattgttca atattctcag ataaatctct aataattgaa 15480 tctttatcat ttagttttcc ttcataatta tttttagaag cagtaatttc atgatcgagc 15540 tcttgaatag ttgattcatc tacttgaatc ttttcctttg cctcttgtag ctgtgacttg 15600 atgttttcca ttaaagaaag agactcactg tgaagctttt gcagggcacc aagcttctca 15660 acagccgaag cgagctcaaa actcttatca tccaaagaag aattaatcga ttcaatcttt 15720 tccattaatg aagaattctt acgcgacgta tcgtccagca tatgttccaa ctcgttttta 15780 gcatccagca aagagctttc tttctgtctt tggttactta aactttcttc caatgaaatg 15840 attaaacttt ctttctcctt taaaacgtct tctttcaggc gaatttcttg atttaaatga 15900 tcaagttgat ttttcagctt atttgtagca agttggttgt cttcaagcct tgaggacaat 15960 tcagctattt cttttttggt ttcctctttg ccttcttcta agctatgtat attttcagtc 16020 atctcggctt ctttccgtaa gaaattcttt tcactatcct tcagtgcctt ttcaagatct 16080 cctctttgaa ttaaccaatc gtcatgttca tgttgcaatt tctccaaatc agcaacaacc 16140 ttggtgaatt cagcgtcggt agtagtcaat cgattatcca attccatttt cttgaagttt 16200 acttgattga aagcgtccaa atagttttcc aaagacagaa cagtcaagcg acttaattca 16260 ctaaagtttc cagcattaaa gacaaaatta tcgtccaaaa tttcagatac cggaacatca 16320 atttcagact tggtacataa ctcacgaaga gaaacagcat acttgttgaa actctcttca 16380 caacccttca gagagtctag caaatcatca cgatcttgac aaacttcgga atattgagta 16440 ctcaaagaat ctttatcctt cttaagagta tccaactcgt catttacacg tacaagatca 16500 gaacgtataa cagatataac attatctgaa tcactcaagg attttttcat gtctgacaaa 16560 cgattagcta agtcactcct ttcttcaacg agtgcttcat tattagaatt ggattgctca 16620 aggcttacaa ttaactcatt tttttcgtta gtcaattgct cgagagcatc actcttttcc 16680 tttaggtcat caacaaaatt tgcacaaaga tcatgctgtt tcttgctctt tttcctcaag 16740 gcaagtaact catccttaat ttgggcattt tcttcgccaa gtttgccata tttggaggtt 16800 agttcttcca actcgacatt cctttgatcc ttttcatcca ataacttttg aacgttcttt 16860 tcaatatact tcaattggtt agttttgtct tcaagagatt tgtttgtttg ggatgaaatc 16920 aacagcaaat tttcgtattc cgagcttaca acagaaagtt ttgactgcaa atcatcattt 16980 tcggcacgtt tcttttcaat ttctgtttgt aaacttgcga tattttcacc attatttttc 17040 aaatcgtcca ttaaacgttc atttgaagct agaagagcat tcctttcaac ttcaacctcg 17100 gaaaccttat ttttcaggtg ttcaatatct gcttcaagct tgctagactt tgacaaagtt 17160 tcatcaagtt tagatttcac agaagttatg gcttgacttt gcgacatgtt ttcttctttc 17220 aagtttgaaa tttcttcttg ccgtgcagtt aattttttac caagatcact ggatttcgat 17280 tcttcaattt ttaacttgcc agttaactta tccaaacgaa tatgtagctc ctcattttct 17340 gtatgtagca attgcttttc agcttccaat gatttcagac cggaatttaa ctgagcagac 17400 tcttgctcca aactatcgta atttttacta agttcagcaa gttgggtaag gatttgatca 17460 ttgtcagaaa tagcaacatt taaactggat cttagattct tcaaatctaa tgataacttt 17520 ccattcacct cttttagttc agaaactttg gattcttgat ttacatgttt atgcatgagt 17580 ttctgaacat tgtcaatgag tgtcatgttc tgttgagtga gattttcaca gtctgtcttc 17640 aattttgatt cagattcaag caatgtatta ttttgagatt gcatattcac atggtcatca 17700 cgaagttcgt ggtacaagtt tgagattgac tgataagaat tgacaaggct tgtaaaactt 17760 tgcttcatag ctttgctatc ttgtgtaaga gtttcaacgt tggcagtcaa cctcttgaca 17820 tcttcagatg atttggtaag ttcactcgac aatattgcat tcgtattttt agcatcagaa 17880 agagaagaat gcaaatcatt tctctgtgct tccaatgtct catgctttcc tttcaaattg 17940 tctatcactt ctctcaaatt tttagcctcc aatttggaaa atcggagggc ttcctccgac 18000 ttccgcaagt cttccttcaa tgtttgaata tttttctcta aagaatccac gtcttcctgt 18060 ttcttaatta acgatttgtt ggactcctcg agctttaata atttagttcg cagatcatta 18120 ttttcgtcgc tcaaggttga ttctttttgt tcgaaattgg ctcgctctaa ttgtagctgt 18180 tgaagttttg aagaagtatc tttcagctgc ttggttatgg tctggtggtt attttctaat 18240 tcttggtgac tttcattgag ttttttaaat gaagtatcca gggaagaaaa gttttgctca 18300 ttctctttca attgcataac cgattttgca agcttttctt gaaaagcatt gcacaatgtc 18360 tgaagtgagt ttttactttc ggaaagttca ttattggtag ccacagctgc ctctttctca 18420 gccgccaaag ttgagagttg ggaggatagg tgttcagaat ttgaaatttc cgtttgtaat 18480 tcacccttca gttcgtttaa ttgactttca taaacttcat gttttttctt ttcatttaaa 18540 atatcacgtt gcaaagactg aaggcttgat tgagtacttt cagaaacttt tttctgttct 18600 ttaatctgct ccctcaaatt atttaactct tgatcttttt tgtcaatcaa cgctgatttt 18660 tccttcagtt cattggatga ggaattcaaa caagcacgca agtcctgctc tatcttttca 18720 aaatctttta tttttttatt ttgaaaatct cgctcggaat ttatctctgc taatttacca 18780 gtcgcgtggg caagggaaga acgagcttct tccaattggg aagaaacttg tttaaccatt 18840 ttatccttcg aagaaagatt attttggtac tcgtcaatag atcctttcag tgatttattt 18900 tcctgttcaa aagaagaaag cttagattca gcatcagtca attgcgaatg gatagtacga 18960 ttggattctt tcaactcaac catttcctct tccaattgag aattggaggt tcgtgagtct 19020 tttaggctgc caatcgtatt acgtagtaac ttttctagct tctcgttttt tattgacaac 19080 gtgtcccgtt cagattttaa attatcaaac tcgcttattc tggtacttaa atcttcaatt 19140 aacttatcct tgtgtactat ggcatctgaa taattggcga cattatgctt aagttcttcc 19200 agcaatttgg aatcttcctc attgatggcg catttctcca acttttcttg caaggtttta 19260 cattcggcgc gcaatgagtt ttctgtttgt cttaaggtac taacagtttt attggagctt 19320 acaagaagtt tttctaatcg ctcttgctca ccacgcaggg acttgttaga agcttgctct 19380 tctgctaaag aggccttgat agaagaaaca tcttctttta ttttttcgta atccttttct 19440 tttttatcta atttttccgt aaccgttaat aactgtcgcg ataaatcgta cgcttcagat 19500 tgtttagcag aaaaatttga ctccatgtta gtgagctttt tttgaaaata tgacacgtct 19560 tcctctgatg ttaacgtggt tacacttgag gtattcttat cctttttatt cgaagatgac 19620 aattgcaagg agagaattcc gttttcatgt tcaagggcag ccagtttgga ccgcacttgc 19680 ttcaactcat ttaaaaggtt ggatttttga gttactgagt taatgtcgag aatcggacta 19740 tcaagtaaac caccgcggac taatagccag ctggcattag aaggagaacg aggtgtcaaa 19800 ggtaatgctg aagaagcagt tgagccttca gaagagccta atttcgcatc aattgaaagg 19860 tcactgtgcc tacgcattcc ccttacttct tgacgcttta actcctctga ggaatcttca 19920 tgttgacttg atgtgtcacc gtcttctgca agttgtcctg ttgaagctct tgaaatattg 19980 ggtcttggtg tttcgagatc agaatcaata aatggtgatg cagcagagct cacaagacta 20040 ctcgctgatt cttcatccaa atcagaagta ttcgaaccag aagacgactg attcgacatc 20100 tgtcgttggt aaataaacga tttgggttgt ttagaaatga caactctctg aagcaacaaa 20160 gcaatagtga taaggtatcg gcatgtttta tcggtattta gcttttgggt ggttgaacaa 20220 aaaagtttca aaaatacatc aatatattga gatataaata aggtaatata tatatatata 20280 tgtatgtata tacatctatt aattagttaa actaaaatct ttaagtaaca ccatggaaat 20340 agagaacgaa ttcatctacg tgattttgta gtccgtcgat aagactgtaa aggaacattt 20400 gtagagcttg gacttaagga gccgttcatt gatagggaat tgctccgtaa agcagcattg 20460 gactgggagc gtagcagttg ctgtgaagga agctccagcg gttgtgcact aagaggaaga 20520 gttccacgat aaaaggcgcc atattgagtg agtgaaagag taaaatcgtc cataagaaaa 20580 tcttctggag acatatcgta atcttttgct aacttaagta tcaagttttg tacttgcaca 20640 gatatttggc gctcctcatc ggagagtacg ttatgagatg tgattctttg attttgaagc 20700 agttgaagat gctgtagtaa cttattcaat tcaacaagtt ccccttgaat aggtacagaa 20760 gtccatgagt cttcttctaa tagactcaaa ttgttttgaa tgatgtcaat atcgattgac 20820 ttctcgacag gtgcctcttt gtaatgacta gatgcccgat aacaagcaac agaatgaaat 20880 gaagaatcag gaataacaga agaagatgaa tttttgtaag gagcaattga ggagaagggg 20940 ccagactgta ggtacttcac agtaggaagt ttagccaatg aaggattaaa ttctataact 21000 gatgcaggag gtttggcggt tgaggggggg gataacttat ccaaggtgta ctcttgggaa 21060 ttagcaacgg atggagttgg caaaagggca actggctttg caattattcc tccatctggt 21120 aatcgactgt ctaatcggga agttcgagca gtagaactga acaaaggacc agcagaaccg 21180 accataaaca aagcgtgtga cctgaattgt ggttgtaaat cttgactaaa ttagtaaagt 21240 ctataaataa aaaaaaaata aaaagaaaag aaaaacattt tcattttaac ttaccatttt 21300 ccaatgaagc ggttgaattt tcagcatcaa aagtgaagcc attttttatt tctttcccaa 21360 caactttact ttgttcgagt gtggtaattc ggttcaccga tgtatataat ttgtcgacat 21420 tccaataatc agcatctttt ggaaagtagg aatgaattat atgcacgcat acattcgtcc 21480 aatcttctag aaactctggg tacctttgat aaacagcgga ctttaagttt gcctcgaggg 21540 tttgcttgtt tgtggtagca gtgcaattca atactagatt gcccgcaggt gcagaagaga 21600 tataggaaag aattaaggag caactttcag cattcattgc cgagtttgtt ttacgaattg 21660 ctatcaaaaa aggccggata acggtaatgc gtttcaaata ctcaaaatat gcccagatcg 21720 ataaaaacca aaaaatttct tttttgaaac catgcaaatt gtaatgtctt agttttttcg 21780 ggcaacctag gtactttgcg cggaacaatc tattatgttc tcttcacttt gcacctttga 21840 ctaccttgtt gatgtgagct atgctagcac cgaagtttta gtacgttggc gatggaagca 21900 cactcgatgt tggcgatata acgaatgata tctgcgaaat tccctaggcc tcgctagaga 21960 tcattattcg gtaaacaaaa gaatggagtg ggttttcatg aaatggacgg attcttttaa 22020 tcggaaagaa atggggtgat aggcatatta gaagataata ataataataa ataataaaaa 22080 gttcatattt tagtaatatg tttttgtaat cgtagcagat ccgatcatag aaaaatggta 22140 tactgtaaat gttaggtgca tttgatacca agctaacagt atcatacatg tagcaacacc 22200 tcattaagta taagaaatca tttgtttcga gtaacccttt caattctaac cagttgcagt 22260 agattaccat gttctgaata tcctagtaat agcctcagca actagaaagt gataacgcac 22320 gtttaatgct gcgtttgtaa tgtttaatgt attactatgc aatatgttat gcaacttgct 22380 gaataagttc tatatagagt acataaagtg aataatagat caagcgaaac ttcaagccta 22440 tcttagcgag gaatgcttaa aactgaacta ttagatactg cagtacgcaa tagcaatttg 22500 tttatgataa ttcagagaaa tttctgtact gtatatatat acacacatac ttgataaatg 22560 aatcattata gatgtctcaa ataaaattat ttttatgcgt ctatattaca ctatttatag 22620 acgactaaac aagttgagca tcacaattgc tcagagttcg gcgattggta gaaacaaagc 22680 atgaacagag aacaaagatt gttttttttt gtgtttttgc tcttgttttc ccccatatca 22740 aaatatcttc tagcagaaaa gacgatggag aattgatgaa attaaatatt ttgacacact 22800 gaaccatggc tttaagttaa cagcagtacc tgcgtatact tagctcgcta aagaagcaga 22860 aatgctcttg aaaacaaagt ctagcattgt ttttatataa agaagttaac aaatttcaac 22920 tcgcaatctc tccacattcc atagcccagc acttgctaaa agacaatttt ttctaaacaa 22980 caacgaaaac attatcgggt tacggcaaag actaaaaaaa ggatgccaat tttctcaaat 23040 tatttttttt gaagggttct gctagatcaa gagcatacaa cagaggtgga ttaaaacagt 23100 ttaccaaaca ccacagtgaa agcaatacac atatgtttga agcgtagtgc tcagtaattc 23160 atatgaagta taattttaat tcagactatg tttgtcataa gatcagcgat ataaatagaa 23220 gaagtgataa aaatgtctat atgaagaaac cataatcgtc aataaatcaa gtattgaaaa 23280 aagaaatcga cgttctcaca caatttacat gcaaaaatca atacttgaaa aaatgtcaac 23340 attctacgct aagcgtttac ttaagaaaat ttgcaactca taatagctca ttaaataaag 23400 gaaaggaact gcttttgttg tagtgagaat gtcactttgg ttccaaatac atcatggatt 23460 gttgtcattc attatgaaat ccccactgac atatgtaact gattagatga aaatctcaca 23520 tttgttttgt cttgcgattt accaccatct tctaagacac tcctttcttt gaagcagcgt 23580 ggtttcagca aacgaaggct tcaactaaac ccttgtttgc ttactttttt atcgtttacg 23640 tttggttgtg gaggttacta tcaggctaca ccaaggtact cttgacttga gcagaattaa 23700 atatatacgc caaccgccga gattttctaa atatgatttt ttatgacaaa ctgaaaccgg 23760 ctgatgtgta agtatacata tatttaacta cttcaactca gtttgtgaac gagattgaaa 23820 aattttcagt acgtcttgca actcgctaac atagattcga ataggctggt tattgggtct 23880 gctgatgggc gagttattga agctatcgag tatattgctg atcttcacaa acagcatggt 23940 tttaaatttg ctatttgtct tggcaatttg ttttcccaca agcgtacaac tagtgcggac 24000 gttgttaaac taaaaaatga aaaagtaaag ggtatgattt tgaatggccg gttttatcga 24060 acgagaaatt cttttcttta atgctttaat cacgattgat aaatctttct tcttattcat 24120 tcttgttgct aacctgagct gtagttccta taccagtcta tttcggggtt ggtactgctg 24180 gtttgccaga gtccattatt tcgcatatgg ccatgtatgg accagaggta gcacctaact 24240 tgttttgtat gggtatttgt gggtttatga aaacttttta caagtttaca attgctcaac 24300 ttggtggatc ttataatgag gagaaatact accaacctcc cgaaaaattt gagcaaagct 24360 taaatgaaaa gtgttttcat cgaagtgatg tacaaaagtt gtctaaacgt tgtgacattt 24420 tgttcagctc tgaatggccg gaggacgtac aagaaaactc tactctccct gagagaaagt 24480 tgcctaaagg ttgtatgccg ttagctgcac tagctgctaa ttgtatgccg cagtactttt 24540 ttgttcctgg gccagtttac tacgaacgtg aaccctacaa aaactctgcc gctattaatg 24600 ttaacactgg tactgtcact catttcgtgg ctttggcccc tttcaaaaac tccaaaaatg 24660 agaagttttc atacgctttt actctctacc ccttgacaac tgagtacatg cagccagctc 24720 ctcctaactg tactgcttct ccatttgagc ataggccaat tcccttaaag cgtgcttcag 24780 aagatcaaat tattccccag caaacaaata aattccataa atctaaatca agcactgctc 24840 tctttaaatc taaaaaagat tctagctcgt ccctcaacaa aatgcacaag tcagagtcac 24900 atagtgcact caataatttg cacaagtccg aatcaggcac ttcgctcaat aatagacggt 24960 ctaaagttgg acgtgagttc cgcttcttat ctctgcgttt tttccaccgt cactaacttc 25020 ttttctcagc cgggtcatgc ttcttttgtt tgagtaatcc aaatgttgca cttcacttaa 25080 tagtcgctat tggtaacgaa gcttacatgg gtacgtttat acactccaat gtttgcgaca 25140 cgctgtttaa attttactct tttttatact aacgactcag cgttgcccaa aggccctctt 25200 actaccacgg catcgaatac cccagcttta gcttcctctg gtcatgtttt gattatacca 25260 attgcgcatg cttctgcttt aagtactttg tcggacacct catatgagaa aactttaaat 25320 gaaatgaatc gatttcgtaa agctgtaact gatatgtaca atgcttgtga ttccgatgct 25380 ttagtatatg aaattagtag agctaacgga gttcatttgc attggcaaat gattcccatc 25440 cccaagattt cctcacatcg tattgaatca gtcttccttg aaatggcaaa ggaagctggt 25500 tacgactttg aggaaaggga tgtagaacct catgagctga actatttccg tgtatttcta 25560 ccctctggaa aaatcttaat tcatcgatta caactaagag aacgatttga tttacagttt 25620 gggcgacgtg ctgctgcaaa aattttgggt cttgaggata gggttgattg gagaaaatgc 25680 gttcagacag aagatgaaga aaaagctgag agtgaagctt tcaaaatgtg tttcaaacct 25740 tacgacttta cataaattta gtatttcatt ataattcata aataaattat ttaaattcat 25800 aactggaaca tcattccatt aaaaggtgga cgtcgcttta ataccttcac ttcctattcg 25860 acgcatggcc tcttcgccgc ccgttgctaa tataggttgt tcaagggctt ctgcaacaca 25920 ttcccatggg cttctactgc caccccatcg taggatggct ttacgaaatt tctcaccagc 25980 ctcacggctt aatggatttc cagcaaaaag tttactaaag attagcgaag ccaataccgt 26040 atcaaaaatg tatgaataat aagtagcgct atatccataa agatgactaa actgaagata 26100 ccaagcagca ggtggagcag actcaaaccc actgaacttt ctggttacat tagtaacttc 26160 atcgatagaa ttaaatgacg gatctaagac aaccttcgag tgaaacaatt gatccaccat 26220 agccatacaa atttgagatt gtaaatctaa gggtgctgaa ctattttcaa ccatgttatg 26280 atggttcaaa acttgtacag gtaatggaat ctcagttcct tcgtagcgag cataaagcgg 26340 taatacggct ggatttgaca taaaaaactc cataataatt gaaggaagtt caacaaagtc 26400 ggttgcacaa cgagttccgg ctaagttctg atatttagta tgacctagaa tggaatgcat 26460 ggcatgcccc atctcgtgaa aaagtgtttt cacatcccac aaatctaaaa aggtaggatc 26520 cattccacta gaacgtacga aattacacaa taacgaaatg acaggtattt gataccgttt 26580 gttatccttg acccttatat tagtagcatc atcaaatcca agacttatag aatcgtcaaa 26640 gcttgtcaag tctaattccc gagaagaacg aattgtaaaa tgagcagctc catctgtttt 26700 tcctgttcga gcaaatagat cgaaataaat tacacccatt acatgatcat tttcattgta 26760 aacattgacc ttatttacat caggatgcca tacctcacca ggggaaatgt ccgctggaac 26820 aaaacgaagc ccatataaag aactaaatag tctagataga ccttgaataa ctgtaccaac 26880 agaaaaaaaa cgccgataat tcgttataga agggtttaaa gaaggctttt gatttataag 26940 agattgttta tagcgagcag tataatattc cctgtcccaa acatcaaatg atggaagaaa 27000 attcaagttt aactcttttt tcttcattaa cgcgagattg tttaaaatct tttttaacac 27060 ggaagaattt tttaatgata agttctctaa aaattcaaca acatgtttag gagcattagc 27120 cattttatct ataagttgta aatctgcaaa actacttttt cccactagtt tcgcaacttc 27180 cgctttagac ctcaaatagg aatttagcaa ttcgacttct tcaactgttc ctttatgacc 27240 ttccatgtaa atttctttcc tgacgtcggg atttgctaca ctaatcaagg cctgtgtacc 27300 ttcgtatcca acagttggaa tcataataaa gtttttgtca ttcttagaga gtgagcgtac 27360 aaaatatggg tccgaaccag ccagacgttg cttagaaata gttaaataac gctgaggacg 27420 attcatgcta ttattaaaaa atgctcttcc aagagttgca gattcagagg actttttaac 27480 aaaggagttt cttttcgagc tctctaaatt tacgcccgat ttttcaaaat cttggaggaa 27540 tactcttcca acagtatatg cttcaggatc tgtatctttc aacgtaggag tctgttgtaa 27600 agaacacttt aatttttcgt aaagaccttg atgagtgttt aaagtgttca tcagctcaaa 27660 tagataactg taagcttctt ctgctttcat taccaccatc ttgtcaggat gggcgcagcg 27720 cacaaactca aaaaggtcaa tgacactgca tagtaagtta gaaatcctgt caaatttgct 27780 gactacaatt gacccgtctt cagtatcctc gagcaaaaga tcctcaatca cggccttaca 27840 tttttcagat gcagtttccg cgagccttag gaagccggta tctttgtcgg aaaggaagtg 27900 attacgaaac aatcctactc cctgaattcc atttcttttc gttatctggt tcacagctat 27960 attctgatca tcaaaaattt gacgcaacaa ttggtcttcc gctttgcgac tttgaacatt 28020 agaatatttt cgataaagac taagaatgca ctgcctattt ccaattactt ttttttttcc 28080 caatgtaagc aaagttctta cttgcatcgt aatatgcgac aaatttttgg tacatgtaca 28140 ggctatatga atggtatata tttccaggag ggtttacttg aaataccaac cacaaaaagt 28200 atccgcatga atagtataca tataaaaaag aaaagcaatc gatcgttcag aagaagaaaa 28260 gtttttggaa atgaaaaaga atttgattta gaag 28294 //