ID SPAC1D4 standard; DNA; FUN; 31201 BP. XX AC Z69239; XX SV Z69239.1 XX DT 02-FEB-1996 (Rel. 46, Created) DT 18-APR-2002 (Rel. 71, Last updated, Version 7) XX DE S.pombe chromosome I cosmid c1D4. XX KW byr1; cct2; CDP-alcohol phosphatidyltransferase; chaperonin; KW conjugation and sporulation; csk1; cyclin suppressing protein kinase; KW DNA repair helicase; golgi peripheral membrane protein; protein kinase; KW rad15; rhp3; serine threonine protein kinase; ste1; KW TCP1 beta subunit homologue; tf2 LTR. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-31201 RA Lye G., Churcher C.M., Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (01-FEB-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; P10506; P10506. DR GOA; P26659; P26659. DR GOA; P36615; P36615. DR GOA; Q10147; Q10147. DR GOA; Q10150; Q10150. DR GOA; Q10151; Q10151. DR GOA; Q10153; Q10153. DR GOA; Q10156; Q10156. DR SWISS-PROT; P10506; BYR1_SCHPO. DR SWISS-PROT; P26659; RA15_SCHPO. DR SWISS-PROT; P36615; CSK1_SCHPO. DR SWISS-PROT; Q09779; YATE_SCHPO. DR SWISS-PROT; Q10147; TCPB_SCHPO. DR SWISS-PROT; Q10148; YAT1_SCHPO. DR SWISS-PROT; Q10149; YAT2_SCHPO. DR SWISS-PROT; Q10150; YAT3_SCHPO. DR SWISS-PROT; Q10151; YAT5_SCHPO. DR SWISS-PROT; Q10152; YAT7_SCHPO. DR SWISS-PROT; Q10153; YAT8_SCHPO. DR SWISS-PROT; Q10154; YAT9_SCHPO. DR SWISS-PROT; Q10155; YATA_SCHPO. DR SWISS-PROT; Q10156; LKH1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1D4 is overlapped at the 5' end by cosmid c1F3 and at the CC 3' end by cosmid c22F3. XX FH Key Location/Qualifiers FH FT source 1..31201 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1D4" FT /map="IL" FT misc_feature 1..133 FT /note="the sequence of this region is derived from cosmid c FT 1F3, the true end of c1D4 is at position 134, while the FT true end of c1F3 is at position 4137 in this sequence" FT misc_feature 1..187 FT /note="nominal overlap with cosmid SPAC1F3, EM:Z70690 S. FT pombe chromosome 1" FT CDS 7..864 FT /db_xref="SWISS-PROT:Q10148" FT /note="SPAC1D4.01," FT /gene="SPAC1F3.11" FT /gene="SPAC1D4.01" FT /product="hypothetical protein; sequence orphan; GFP fusion FT nuclear" FT /protein_id="CAB56125.1" FT /translation="MRQIFGTCTGYMNGIYFQEGLLEIPTTKSIRMNSIHIKKKSNRSF FT RRRKVFGNEKEFDLEELDDNDIRLRQALEATKRRKIRNSIIGINAEKLLNQETKKEKQL FT NTANEPHEANDQTSAQSSKLIEAQLPTVEDRFAKQTNEVDINTHLLNFVEKKLKQERLA FT QNYSENGETNALNTKNESTVQNIKNSLHPNEHSFIRDAAALGAIREVDLGIISTDVDNL FT KNGRKRQKKRARMKEKLDSKALRTSEDAARDEFIEKMLKPISQDEESKGIYRRFRVYKD FT GTQD" FT CDS join(complement(2137..2316),complement(1970..2090), FT complement(1686..1873),complement(1088..1636)) FT /db_xref="SWISS-PROT:Q10149" FT /note="SPAC1D4.02c, len:345, SIMILARITY:Rattus norvegicus, FT O35254, golgi peripheral membrane protein p65., (451 aa), FT fasta scores: opt: 493, E():4.7e-20, (34.4% identity in 305 FT aa)" FT /gene="SPAC1D4.02c" FT /product="putative spindle checkpoint by similar to S. FT cerevisiae grh1, has similar to mammalian GRASP proteins" FT /protein_id="CAB56126.1" FT /translation="MFGGLKNFIKEKSEALAGIHRESDESCGFRVLKVENDSKAYNARI FT ESYYDFITAVNGILLNGDPSMFMALLRDSSPEVTLEVFSLKGQITRKVNIKINSDEKIG FT MVLQWASIAPAVDAIWHILNVIDDSPVARASLVPYEDYIVGTPEGMMTGEKALSDLIES FT HLNRPLRLYIYNHYRDSTRQVTIVPNRHWGGNGAIGCGVGHGVLHRLPAPLSGPPPQPG FT DIVFSNPMLGGPDHKVSQPSETENFLPTPEPPKIASANAGSSNEISIPHYQRHKKSHKG FT AIQDSSIQSYLDEEEKLSRELDHKTKDASSTNDSQTTPLPPPPPVAVNSTNDESAPQNE FT ELVKN" FT misc_feature complement(1637..1651) FT /note="splice branch and acceptor sequence, FT ctaacaatttaacag" FT misc_feature complement(1680..1685) FT /note="splice donor sequence, gtatgt" FT misc_feature complement(1874..1886) FT /note="splice branch and acceptor sequence, ctaacgactacag" FT misc_feature complement(1964..1969) FT /note="splice donor sequence, gtaagt" FT misc_feature complement(2091..2108) FT /note="ctaaagtgtttttcacag, splice branch and acceptor" FT misc_feature complement(2131..2136) FT /note="gtatga, splice donor sequence" FT CDS join(complement(2907..4201),complement(2574..2820)) FT /db_xref="GOA:Q10150" FT /db_xref="SWISS-PROT:Q10150" FT /note="SPAC1D4.03c, len:513, SIMILARITY:Fugu rubripes, FT Q9YGN1, sand protein., (520 aa), fasta scores: opt: 609, FT E():7.2e-32, (28.5% identity in 407 aa)" FT /gene="SPAC1D4.03c" FT /product="hypothetical protein; similar to S. cerevisiae FT YGL124C; highly similar to pufferfish SAND protein, a FT receptor for plasminogen related growth factors?" FT /protein_id="CAA93212.1" FT /translation="MEPTSEHSSIKEEVENDNVHRSHESECGSLLLNPGNVLMAAPSVS FT EDDQEVSRSTPELRSHVENVEQLLSDILHDNSSPLNVSTSVSSSSNNTAVDEIIKLLSL FT ISFDLAKQKRTYLIFSSSGKPVFSNIVDDSIEPSTVGALQAIISSFEVSKEELTSFSTF FT SNVIVVLSKNPLYLVGVSPSTTLSAAYLLSELNLLYCQILTGVTAKAMQLTLNSRPNFD FT LRRLIGSNEQFLKELCDQLNDYELVPTLNAISPLPLRSSFRDQLSQLLLRETPKSLLFT FT FIAIRGRLVCMVKAKKLLLHANDLYLLFLSLFRTQSFNDSMEHWVPVCFPTLNPDAYIY FT IYSYFLCKDTVLIMGSSESGVFFEMQSVKCKVAQEIQDHGWLKKLIYCEEMDRTTPRNP FT GSPCISHYLFYSKKYSQFYTPGYSFSTPNFNTRTLYAIYASLHDQAFHKKNSFSINMTV FT HESLLLFTWSTASFDFHCIANATTSSQLLIANVNKILRWIRREENRLFIQTNLSF" FT misc_feature complement(2821..2836) FT /note="splice branch and acceptor sequence, ctaactatgttttta FT g" FT misc_feature complement(2901..2906) FT /note="splice donor sequence, gtacgt" FT CDS join(5400..5402,5439..5570,5618..7066) FT /db_xref="GOA:Q10147" FT /db_xref="SWISS-PROT:Q10147" FT /note="SPAC1D4.04, len:527" FT /gene="SPAC1D4.04" FT /gene="cct2" FT /product="t-complex protein 1, beta subunit" FT /protein_id="CAA93213.1" FT /translation="MSLNPHQIFNESGIQERGENARLSSFVGAIAVGDLVKSTLGPKGM FT DKILQSNSSGDIVVTNDGATILKSIALDNAAAKVLVNISKVQDDEVGDGTTSVCVFAAE FT LLRQAEIMVNAKIHPQVIIDGYRIATKTAIDALRASSIDNSSDPAKFRSDLENIARTTL FT SSKILSQNKNHFAQLAVDAVLRLKGSTNLDNIQIIKILGGKLDDSFLDEGFILNKTIGV FT NCPKVMENANILIANTAMDTDKVKVFGARVRVDTTGKLAELERAEREKMKAKVEKIKSH FT NINCFINRQLIYNWPEQLFADAGIMSIEHADFDGIERLSLVTGGEIASTFDHPELVKLG FT HCKKIEEIIIGEDKMIKFSGVEAGEACTIVLRGATHQLLDESERAIHDALAVLSQTVAE FT SRVTLGGGCAEMLMAKAVEEAATHEPGKKAVAVSAFAKALSQLPTILADNAGFDSSELV FT AQLKAAHYDGNDTMGLDMDEGEIADMRAKGILEALKLKQAVVSSGSEGAQLLLRVDTIL FT KAAPRPRERM" FT misc_feature 5425..5438 FT /note="splice branch and acceptor sequence, tactaacgatatag" FT misc_feature join(5529..5570,5618..7045) FT /note="Match to PF00118 cpn60_TCP1, TCP-1/cpn60 chaperonin FT family Score 590.77" FT misc_feature 5571..5576 FT /note="splice donor sequence, gtaagg" FT misc_feature 5604..5617 FT /note="splice branch and acceptor sequence, ttaacgatttatag" FT misc_feature 5741..5767 FT /note="PS00995 Chaperonins TCP-1 signature 3" FT CDS join(complement(8419..8497),complement(7282..8366)) FT /db_xref="GOA:Q10151" FT /db_xref="SWISS-PROT:Q10151" FT /note="SPAC1D4.05c, len:387, LOW SIMILARITY:Mus musculus, FT Q9Z0U0, polytropic murine leukamia virus receptor syg1., FT (695 aa), fasta scores: opt: 261, E():1.5e-10, (25.1% FT identity in 398 aa) also shows low similar to, FT Saccharomyces cerevisiae, ERD1_YEAST, ERD1 protein., (362 FT aa), fasta scores: opt: 187, E(): 1e-05, (23.6% identity FT in 382 aa)" FT /note="SPAC1D4.05c, len:387, SIMILARITY:Mus musculus, FT Q9Z0U0, polytropic murine leukamia virus receptor syg1., FT (695 aa), fasta scores: opt: 261, E():1.5e-10, (25.1% FT identity in 398 aa)" FT /gene="SPAC1D4.05c" FT /product="protein similar to S. cerevisiae ERD1-protein FT required for retention of luminal ER proteins" FT /protein_id="CAA93214.1" FT /translation="MDLEVVEFPLHHKLALPFRIGLLVIVGTWLWSVCYHLIYILNRYQ FT PISPNPRGSLNSKWYHLLQIPLSNRHTDLEENTEFKANLVSPVDFHAGYCFAAILSISW FT ATGFILFLKKTQGDIGGLYSHPIYPLLWVITAFILIVFPFPWRYRSSQRGLRKSIIRVF FT LFFQADFRSPYKDFIVSEIFTSYAKALGDFYIFGCVLQGHISKFTLRPDLKCDGTFFVP FT LAMAYPFIVAILQCLHYGLSRRKHTFKINLLSALKHATALPVIYLSAIIHAKQTKFTLT FT SGHGYLFWLWILSALLSSAYTFLWDVFIDWRIRFPFHKSINHKRFPMFIYAIGCFINFI FT LRVTWSMKLHPRLHQFHEYEMGIFSFEMLEILRRFLWLFFHLDAISS" FT misc_feature complement(8367..8389) FT /note="splice branch and acceptor sequence, tactaacaatctcta FT ttctttag" FT misc_feature complement(8413..8418) FT /note="splice donor sequence, gtatga" FT CDS join(complement(9579..10082),complement(9303..9518), FT complement(8990..9190)) FT /db_xref="GOA:P36615" FT /db_xref="SWISS-PROT:P36615" FT /note="SPAC1D4.06c, len:306" FT /gene="csk1" FT /gene="SPAC1D4.06c" FT /product="cyclin dependant kinase activating kinase (CAK) ; FT serine/threonine protein kinase; similar to S. cerevisiae FT CIV1" FT /protein_id="CAA93215.1" FT /translation="MKSVGHFVPWLTDIRHLTDGTISEVFVGERKNSKKLYVIKVQGLV FT FKRPPHDAMRGKLILESIGHPHIERIVDSFIDNEAGSVYLITSFKSFVLSDVMDEISID FT TKCKIVLQISSALEYLEKHGILHRDIHPNNILLDSMNGPAYLSDFSIAWSKQHPGEEVQ FT ELIPQIGTGHYRAIETLFGCHSYGHEVDRWTFGILIAELFSNQALFDDGSSEGWPSELR FT LTSSIIQTLGTPNPSMWPELSTFPDWNKFIFHEYPPKPWSEILPSVDTSIQYIVSHLVT FT YSNRASPSFVIESFPKVSARLSQYA" FT misc_feature complement(9191..9205) FT /note="splice branch and acceptor sequence, FT ctaactgtttttaag" FT misc_feature complement(9297..9302) FT /note="splice donor sequence, gtaagt" FT misc_feature complement(9519..9534) FT /note="splice donor sequence, ctaacgttttttttag" FT misc_feature complement(9573..9578) FT /note="splice donor sequence, gtatgt" FT misc_feature complement(9636..10052) FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 58.05" FT CDS complement(10138..10578) FT /db_xref="SWISS-PROT:Q10152" FT /note="SPAC1D4.07c, len:146" FT /gene="SPAC1D4.07c" FT /product="very hypothetical protein" FT /protein_id="CAA93216.1" FT /translation="MISKTIKTLIITKIFFSFKQTKRKKNKNKKRILSILPYYKNSYSD FT FISVLQMYKVHIRMVSIYIFLKALSNIFLASSCEITVRLSSGGHPSPPVHIYMSALIKV FT CKKSKPHLQTHCIKRKTYCVKHLAISNFQSFILQRFSCFLFC" FT CDS join(11503..11582,11862..12537) FT /db_xref="GOA:Q10153" FT /db_xref="SWISS-PROT:Q10153" FT /note="SPAC1D4.08, len:251, SIMILARITY:Saccharomyces FT cerevisiae, PIS_YEAST, cdp-diacylglycerol--inositol FT 3-phosphatidyltransferase, (220 aa), fasta scores: opt: FT 503, E():2.5e-27, (40.6% identity in 217 aa)" FT /gene="SPAC1D4.08" FT /EC_number="2.7.8.11" FT /product="putative cdp-diacylglycerol--inositol FT 3-phosphatidyltransferase" FT /protein_id="CAA93217.1" FT /translation="MRVKFLKLSNDFPFCSGQAMSGVLDTFILTLCLGFTRVFLVLISL FT YFMSWHPNYCTIVYLYSSLLDAFDGWAARKLHQATNFGAILDMVTDRCATSCLLCFLCA FT AYPKYAIIFQLLVSLDLASHYMHMYSTLHQGASSHKTVTKKHNWMLRLYYGNNKVLFIF FT CAANEMFFVALYLLSFTPRTPPKLGYLPVPSFIYSTGELPLSYPTLLAVLCGPICLAKQ FT IINVVQLVNAANALVKMDVEQRRAAKKLQ" FT misc_feature 11583..11588 FT /note="gtatgc, splice donor sequence" FT misc_feature 11947..12486 FT /note="Match to PF01066 CDP-OH_P_transf, CDP-alcohol FT phosphatidyltransferase Score 206.98" FT misc_feature 11986..12054 FT /note="PS00379 CDP-alcohol phosphatidyltransferases signatu FT re" FT CDS join(complement(13911..13923),complement(13452..13867), FT complement(13265..13387),complement(13048..13218)) FT /db_xref="SWISS-PROT:Q10154" FT /note="SPAC1D4.09c, len:240, SIMILARITY: Caenorhabditis FT elegans., O02209, C01A2.5 protein, (300 aa), fasta scores: FT opt: 135, E():0.053, (32.4% identity in 204 aa)" FT /gene="SPAC1D4.09c" FT /product="conserved protein; no apparent S. cerevisiae FT ortholog" FT /protein_id="CAA93218.1" FT /translation="MGNDGGSLPTRNELVKEPGKVPPLDIDFKRSVKSSQFSQCAITDE FT PLYPPIVSCGLGKLYNKASILQMLLDRSSVPKSPSHIKSLKDVVQLQVELDDSGKVLWL FT CPITRHVMSDTYQFAYIVPCGHVFEYSALKQFGEKMCFQCNQVYEEKDVIPINPNAEQL FT KTLSKRLLDLALSEKTHSLNKASKKSNKNGDKKRKHVSKSNSKHAKHELRTNRMLDGEN FT VKSETSVTDMERVKRVKI" FT intron complement(13219..13264) FT /note="confirmed intron" FT misc_feature complement(13388..13402) FT /note="ctaacacaacatcag, splice branch and acceptor" FT misc_feature complement(13446..13451) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(13868..13881) FT /note="ttaacatgttttag, splice branch and acceptor" FT misc_feature complement(13905..13910) FT /note="gtagga, splice donor sequence" FT CDS join(14463..14847,14885..16929) FT /db_xref="SWISS-PROT:Q10155" FT /note="SPAC1D4.10, len:809, LOW SIMILARITY:Saccharomyces FT cerevisiae, YK59_YEAST, hypothetical 96.8 kD protein in FT sis2-mtd1 intergenic region., (838 aa), fasta scores: opt: FT 307, E():1.4e-11, (27.7% identity in 860 aa)" FT /gene="SPAC1D4.10" FT /product="hypothetical protein; similar to S. cerevisiae FT YKR079C" FT /protein_id="CAA93219.1" FT /translation="MSKTVNFRATKNFYLQFVSVSSRDTSCIPCIHLFFDSKRYVFGSV FT GEGCQRAILSQQLRLSKIKDVFLMQGSSISSPDTYDSSSSSSTTSVSDMLQLDDRDKVI FT VSERNSMCSTVNYPTWWDSCGGFPGFLLSLNDISEPGETGEASPFVLHGPSEVHQFLSS FT MRHFTYHTNVNLTVQGYTSAEAPVFVDENICVTPVVVSLVKNSFKKRKHENINRGTNAR FT PLKEDRANTSPHWYSHVSNDTSFVVENAMYNTPAPLEPDKPELFISYIVQSHPTPGKFD FT AAKAKSLGITKGLDCGRLARGEPVTLENGKTVYPKEVIGPSIPGSSFFIIHCPNELVID FT LVIENHKWTNAPKPVCVIHSVTPEVYKNPRYQSWISSFPSEVSHLIASTEVNEVINYPR FT SAVAIATLNLLDSKVFPLGFNCYEVKNVQKNNRIAFAKPKLRFAFGKKTGIDDSEVGVS FT IEELKDKILKEKPDYKSFVEEAQKYVSDKPKAPSFAGSDIQICTLGTGSAMPSLYRNVS FT STYVRIPVDKKCMEDSAISMKNILLDCGEGTLGRLSRQYGDNLKYEIASLRWIYISHMH FT ADHHAGVIGVLKAWTKYSDGRSKLFITAPPQFEFWLLEYSRIDYLPLSNIVFISNSALR FT TDRKPSALESSRLSSLFKEFDLVSFRTVPAIHCPYSYCMEITNSSGWKIAYSGDTRPSE FT DFANIAKDSTLLIHEATLEDSMHEIAIKKQHSTYSEALEVAKKAGTKNVILTHFSQRYP FT KLPDIDISTEDLHIALAFDGMTLKISDISLFRYFGKPLAYLFNEENLKEESDPLKF" FT misc_feature 14848..14853 FT /note="splice donor sequence, gtaagt" FT misc_feature 14865..14884 FT /note="splice branch and acceptor sequence, ttaataatttctgac FT aatag" FT CDS complement(17449..19176) FT /db_xref="GOA:Q10156" FT /db_xref="SWISS-PROT:Q10156" FT /note="SPAC1D4.11c, len:690, SIMILARITY:Arabidopsis FT thaliana, Q39184, protein kinase., (467 aa), fasta scores: FT opt: 1120, E():0, (42.8% identity in 421 aa)" FT /gene="lkh1" FT /gene="SPAC1D4.11c" FT /product="dual specificity protein kinase; LAMMER family; FT negative regulator of filamentous growth and flocculation; FT serine/threonine protein kinase; similar to S. cerevisiae FT KNS1" FT /protein_id="CAD29835.1" FT /translation="MVQSPTSYHACSNNQSPFPHSHHPPLHNPLPVSCQPVLRPPPVPQ FT VPSHWYPVSLPSPNLPHQPISKPPVIPNLPKLQVHPNRLPHPIHNHPYSSPTSYPPPLC FT PATYCPSNPPQLAPATAIAPSSQSSQHKSVNYSVTPSSINNHTAVPLSPTLAVWLPMTQ FT PTFQPPSANVYQPASNANQVITPVSISDYRPPKKRKRAAWPPYKKVDRVNVPVVHDTTA FT FDPSTFDDDDGHYKVVPNSKFANRYTVVRLLGHGTFGKVIQCYDQSTGRHCAIKVTRAI FT PKYREASLIELRVLQTIAHSDPTNENKCIQLRDYFDYRKHICIVTDLFGWSVFDFLKNN FT NYIPFPLKHIQMLSQQLFKSVAFLHSLGLVHTDLKPENVLLVSNASRTIRLPYRNYSQK FT VLNSCEIRLIDFGSATFEDEYHSSVVSTRHYRAPEIILGLGWSYPCDVWSIGCILVELF FT TGQALFQTHEDSEHLCMMEKILGPFDRNMISRSSRTSQRFFKSDGKVRYPLSNTPKKSI FT NYLQSLQTLEQIFAVSSPEVALLLDLLKKVFVYDPKRRITAKEALWHPFFTQPISSNL" FT misc_feature complement(17476..18438) FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 233.86" FT misc_feature complement(18034..18072) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(18349..18420) FT /note="PS00107 protein kinases ATP-binding region FT signature" FT misc_feature complement(19522..25470) FT /note="low complexity gene-free region" FT misc_feature 21356..21472 FT /note="repetitive DNA similar to H. sapiens" FT misc_RNA complement(23833..24041) FT /note="cDNA EST, but cannot predict corresponding gene FT here" FT CDS 25471..27789 FT /db_xref="GOA:P26659" FT /db_xref="SWISS-PROT:P26659" FT /note="SPAC1D4.12, len:772" FT /gene="rad15" FT /gene="rhp3" FT /gene="SPAC1D4.12" FT /product="DNA repair protein; transcription initiation FT factor TFIIH subunit; involved in excision repair; FT DEAD/DEAH box helicase; Xeroderma pigmentosum group D FT protein signature; similar to S. cerevisiae RAD3" FT /protein_id="CAA93221.1" FT /translation="MKFYIDDLPILFPYPRIYPEQYQYMCDLKHSLDAGGIALLEMPSG FT TGKTISLLSLIVSYQQHYPEHRKLIYCSRTMSEIDKALAELKRLMAYRTSQLGYEEPFL FT GLGLTSRKNLCLHPSVRREKNGNVVDARCRSLTAGFVREQRLAGMDVPTCEFHDNLEDL FT EPHSLISNGVWTLDDITEYGEKTTRCPYFTVRRMLPFCNVIIYSYHYLLDPKIAERVSR FT ELSKDCIVVFDEAHNIDNVCIESLSIDLTESSLRKASKSILSLEQKVNEVKQSDSKKLQ FT DEYQKLVRGLQDANAANDEDQFMANPVLPEDVLKEAVPGNIRRAEHFIAFLKRFVEYLK FT TRMKVLHVIAETPTSFLQHVKDITFIDKKPLRFCAERLTSLVRALQISLVEDFHSLQQV FT VAFATLVATYERGFILILEPFETENATVPNPILRFSCLDASIAIKPVFERFRSVIITSG FT TLSPLDMYPKMLQFNTVMQESYGMSLARNCFLPMVVTRGSDQVAISSKFEARNDPSVVR FT NYGNILVEFSKITPDGLVAFFPSYLYLESIVSSWQSMGILDEVWKYKLILVETPDPHET FT TLALETYRAACSNGRGAVLLSVARGKVSEGVDFDHHYGRAVIMFGIPYQYTESRVLKAR FT LEFLRDTYQIREADFLTFDAMRHAAQCLGRVLRGKDDHGIMVLADKRYGRSDKRTKLPK FT WIQQYITEGATNLSTDMSLALAKKFLRTMAQPFTASDQEGISWWSLDDLLIHQKKALKS FT AAIEQSKHEDEMDIDVVET" FT CDS 28842..29864 FT /db_xref="GOA:P10506" FT /db_xref="SWISS-PROT:P10506" FT /note="SPAC1D4.13, len:340" FT /gene="byr1" FT /gene="ste1" FT /gene="SPAC1D4.13" FT /gene="ste3" FT /product="serine/threonine protein kinase; MAPKK; FT conjugation and sporulation protein kinase; pheromone FT signalling pathway" FT /protein_id="CAA93222.1" FT /translation="MFKRRRNPKGLVLNPNASVKSSDNDHKEELINNQKSFESNVEAFM FT EQCAHMNRRPAWISDLDNSSLEVVRHLGEGNGGAVSLVKHRNIFMARKTVYVGSDSKLQ FT KQILRELGVLHHCRSPYIVGFYGAFQYKNNISLCMEYMDCGSLDAILREGGPIPLDILG FT KIINSMVKGLIYLYNVLHIIHRDLKPSNVVVNSRGEIKLCDFGVSGELVNSVAQTFVGT FT STYMSPERIRGGKYTVKSDIWSLGISIIELATQELPWSFSNIDDSIGILDLLHCIVQEE FT PPRLPSSFPEDLRLFVDACLHKDPTLRASPQQLCAMPYFQQALMINVDLASWASNFRSS FT " FT misc_feature 29037..29801 FT /note="Match to PF00069 pkinase, Eukaryotic protein kinase FT domain Score 309.65" FT misc_feature 29055..29120 FT /note="PS00107 protein kinases ATP-binding region FT signature" FT misc_feature 29385..29423 FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT LTR complement(30475..30820) FT /note="tf2 type LTR" FT CDS join(31068..31116,31172..>31201) FT /db_xref="SWISS-PROT:Q09779" FT /note="SPAC1D4.14, len:26" FT /gene="SPAC22F3.14c" FT /gene="SPAC1D4.14" FT /product="possibly involved in transcription by RNA FT polymerase II; similar to S. cerevisiae RLR1" FT /protein_id="CAA93223.1" FT /translation="MTSLPEKDQQGEVSVSENQKKLSEEW" FT misc_feature complement(31089..31201) FT /note="nominal overlap with cosmid SPAC22F3, EM:Z54285 S. FT pombe chromosome 1" FT misc_feature 31117..31122 FT /note="gtaaga, splice donor sequence" FT misc_feature 31152..31171 FT /note="ttaacagaatataattttag, splice branch and acceptor" XX SQ Sequence 31201 BP; 10129 A; 5349 C; 5870 G; 9853 T; 0 other; cgtaatatgc gacaaatttt tggtacatgt acaggctata tgaatggtat atatttccag 60 gagggtttac ttgaaatacc aaccacaaaa agtatccgca tgaatagtat acatataaaa 120 aagaaaagca atcgatcgtt cagaagaaga aaagtttttg gaaatgaaaa agaatttgat 180 ttagaagaat tagatgataa tgatattcgt ctacggcaag ctttggaagc tactaagagg 240 cgaaaaatta gaaattcgat tatcgggata aatgctgaaa agttattaaa tcaagaaaca 300 aaaaaagaga aacaattgaa cactgctaat gagcctcatg aagctaatga tcagacctca 360 gctcaatcgt cgaaacttat agaggcgcaa cttccaaccg tcgaagatag gtttgctaaa 420 caaacaaacg aggttgacat caacacgcat ttattaaact ttgttgaaaa aaaactgaaa 480 caggaaaggt tggcccaaaa ctactcagaa aatggagaga ctaatgcact taatacaaaa 540 aatgaatcga cggtacaaaa cataaaaaat tccttacatc caaatgaaca ttcatttatt 600 agagatgcag ctgctcttgg tgctatacgt gaagtagatt tagggattat tagtaccgac 660 gttgataatt tgaaaaatgg tcggaaacga caaaaaaaaa gagcaagaat gaaagaaaaa 720 ctagactcga aggctcttcg cacctctgag gacgctgctc gggatgaatt tattgaaaaa 780 atgttaaaac cgatatccca agatgaagaa agtaagggaa tctacaggcg ttttcgcgtt 840 tacaaggatg gaactcagga ttaacgataa taaaaaagaa gcaacagttt ggcaaggttc 900 attaattcaa attatttatt acattttttg agtaatcaat tcggataaag aggtttgttt 960 gtgttttata aaatccttac tcaaaacctc aaatgtttat ttatcaaaaa tatagttttg 1020 taacttttaa tcattatggg cattaaaaag agggcttttg ctagaaaaga cgagcttaac 1080 taaataacta atttttcaca agttcttcat tttgaggcgc tgattcatcg tttgttgaat 1140 taacagcgac aggaggagga ggaggcaaag gagttgtttg ggaatcgtta gtagaagaag 1200 cgtctttggt tttatgatcc aattctctgc ttagtttttc ttcttcatct aaatatgatt 1260 gaatagaaga atcttggata gcgcctttat gagacttctt atgtctttga tagtgcggga 1320 tagatatttc attgctagat ccagcattag cagaagcgat tttaggtggt tctggagtag 1380 gcaaaaagtt ttcagtttca ctgggctgag acactttatg atctggaccc cccagcatgg 1440 gatttgaaaa cacaatgtcc ccaggttgtg gaggaggtcc tgacaaagga gcgggtaagc 1500 gatgcaagac gccatgtcca acaccacatc caatagctcc attacctccc caatgacgat 1560 ttgggacaat ggtaacttga cgagtggagt cgcgataatg attgtagata tacaggcgta 1620 agggtctgtt gagatgctgt taaattgtta gtcaaataat ttatcttagc acataattta 1680 catacagact caattaggtc tgaaagcgct ttttctcctg tcatcattcc ttcaggagtt 1740 ccgacgatat aatcttcata cggaacaagg ctagctcgtg caacaggaga atcgtctata 1800 acattcaaaa tatgccaaat ggcatccacg gcaggagcga ttgatgccca ctgtaaaacc 1860 atgccaattt tttctgtagt cgttagaaaa tttatttgta ttcaataagc gttcataaaa 1920 atacatccaa aaaagatata agaatcgtta accgcagcta gaaacttacc gtcactgtta 1980 attttaatat taactttcct cgtaatttgc ccttttaaag aaaatacttc taaagttact 2040 tcgggggaag aatcacgaag caaagccata aacattgaag ggtctccatt ctgtgaaaaa 2100 cactttagta atgataaaac tataatcagt tcataccagt aagatcccat tcactgccgt 2160 tataaaatcg taataagact caattctggc attataggct ttcgaatcgt tttcaacctt 2220 taatactctg aaaccacatg attcatctga ttctcgatga ataccagcta aagcttctga 2280 tttttcttta ataaagttct ttaaaccacc aaacatttcg attgtttagt acttaaatag 2340 ggttggtggt gatttaggta atggcgcggt tgactcgcta tgatattaag ttcatacagt 2400 cggaaattta tgtgagtaaa atgatgctga tattaataaa ttaaaacaaa aaaaggaaaa 2460 agaaaaatta ataaagctgt tggaagcaat caccgctctt ttaaatattt tactgtcaaa 2520 acatcataaa aaataaaaag aaatgaattt cattaaactt tacatgctca ttatcaaaac 2580 gaaaggtttg tttgtataaa taatcgattc tcctcccttc gtatccatct caaaatctta 2640 ttaacatttg caataagcag ttgactgcta gtggtagcgt tagcaataca atgaaagtcg 2700 aacgatgcag ttgaccacgt gaatagaagc aaagattcat ggacagtcat attaattgag 2760 aaagaatttt ttttgtgaaa tgcctggtcg tgtaagctag cataaatagc ataaagagtt 2820 ctaaaaacat agttagcaaa gcaaatgagc ccaaagatag cgatcgtatt gaaattgtaa 2880 agaaaaatag atcattgtat acgtacctag tattgaaatt gggagttgaa aatgaatagc 2940 caggagtata aaactgtgag tatttctttg aataaaacaa gtaatgtgaa atacaaggag 3000 atccgggatt ccttggcgta gttctatcca tttcttcaca ataaatgagc tttttcaacc 3060 atccatgatc ctgaatttcc tgagcaactt tgcatttcac tgattgcatt tcaaaaaaga 3120 caccactttc gctgctcccc attatcaaga cagtgtcctt acataggaaa tagctataaa 3180 tgtaaatata agcatctgga tttagagtag gaaaacaaac aggcacccaa tgctccattg 3240 aatcattaaa agactgtgtg cggaagagtg ataggaaaag taaatagaga tcattagcat 3300 gtaataaaag cttcttcgcc ttaaccatac aaacaagccg acctcgtata gctataaaag 3360 taaacagcag agatttgggt gtttctctca acagcagttg cgacagctga tcacgaaaag 3420 aggaacgtaa aggaagagga gatatggcat tcaatgtggg gactaattca taatcattaa 3480 gttgatcaca tagttctttt aggaactgct cgttgcttcc aataagtctt ctcaaatcaa 3540 aatttgggcg ggagtttaag gtcagctgca tagctttcgc agtaacccca gtaagtattt 3600 ggcaatataa gaggtttaac tcactgagta aatatgctgc gcttaaagtt gtcgatggcg 3660 atacgccaac aagataaaga ggatttttgg agagaacaac gataacattg gaaaaggtag 3720 aaaagcttgt tagctcttct ttcgacactt cgaaagagct aataattgct tgtaacgcgc 3780 caacggttga tggctcaatt gaatcatcaa caatgttact aaacacgggc ttccctgatg 3840 aagagaatat caaatatgtg cgcttttgtt ttgccaaatc aaaagatatc aacgaaagta 3900 gttttataat ttcatcaaca gccgtattgt tactactgct cgatactgaa gtgcttacat 3960 taagcggaga ggaattatca tgcaatatat cagaaagtaa ttgttcaacg ttttccacgt 4020 ggcttcgcaa ttctggtgta gacctgctta cttcttgatc atcctctgac accgaaggcg 4080 ctgccattag aacattacca gggtttaaca gcagtgatcc acattccgac tcatgagatc 4140 tatgaacgtt atcattttcc acttcctcct tgattgatga atgctcagat gttggttcca 4200 tcaactggct gttttcatta gtgggatgga ttgaataagg aggactgtag ctgttgtaat 4260 aatgctaacc tcgcttcatt cactcattta cggttaaaat taagggaaaa gaaggcgttt 4320 taaatatttt gctttttatt gaataaaaaa taattattga ttctttaaat aaatgttgaa 4380 actcaacttt gcggtgcaat cataaagata ttgtgccgaa gatgatttcg tacctagttg 4440 tataggtaat tcaaaaggga agattggaat ggctgagtct tcggcaaaga atttcatatt 4500 acaactaaat ggcattcaag atacgtttac atggaagtca attgtataca gagaacagta 4560 ctgaatttaa aataaaacta ataattacac gttctatgaa atgtacgcgc tctaaactaa 4620 gaatactctt tggttaagaa attaatgtta aaaagcgctt agaatatagc gctagatgta 4680 ttactacaaa ctgtttatat tgagttattt aggagtgatc actgatctat cgtttcaact 4740 aaaatgctgc ttatccttga cttctcaagg tctaaggatg gtattcacat ttaaagatct 4800 agaaacttgt tggctaactt ttcgagatgg ttccatctaa tattgaatag aattgagatt 4860 tgcgcattgg ttctttcaat atctatattg ctccaaaaca aaaacattag tctagtactt 4920 gtaagaaaac acaagtcata cagggaatcg aaaataaaaa atcagttgaa atctttaatc 4980 gacgcttcat atttcatttt gagcaataat aaaacactcg attaagccaa ccatcatcta 5040 gtttgttgaa catgctcagt agtcggtatt aacttcatag agacttgaat agatatagga 5100 aatcttttaa ttttttgata ttttatattt gagagtaata gaatagtgtt ttatatagca 5160 atgcttaaaa gctgtctcat tattttcttt tgcatgaata tgaacgtaag agaatgaaat 5220 atatatatta taaaaatatt tgattataat attatttacg atccaaaact agaaatatac 5280 agtcgctggt acatgcctgg taagctacgg cttacgttgt tgcgacgagc ttcttgttcg 5340 ctgtaagcta ctttccactc aaccaccgca actctgggtt tatcgtacac tatctggaaa 5400 tggtaatatc atgtgtaaaa accgtactaa cgatatagtc tttaaatcct catcagattt 5460 ttaacgaaag tggcatccaa gagcggggtg aaaatgcccg tctttcatcg tttgtgggtg 5520 caattgctgt gggcgatttg gtaaaaagca ctttaggtcc taagggaatg gtaaggtcaa 5580 atctacatag aaaaaatttt taattaacga tttataggac aaaattttac aatcaaactc 5640 ttcgggtgat attgttgtga caaatgacgg tgctaccatt cttaagtcta tagctttgga 5700 taatgcagct gctaaagttt tagtgaatat ctcaaaagtc caagatgatg aagttggcga 5760 cggtactacc agtgtgtgtg tcttcgctgc tgaacttctt cgtcaagcag aaattatggt 5820 caatgcaaaa atacatcctc aagtgattat cgatggttat cgtattgcta ctaaaactgc 5880 tatcgatgct cttcgtgctt cctctattga taattctagt gatcctgcta aatttcgtag 5940 tgacctcgag aatattgcca gaactactct gtcttccaaa atcttatctc agaataaaaa 6000 ccattttgct cagctggctg ttgatgcagt gcttcgcttg aaaggtagca cgaacttgga 6060 taacattcaa attattaaga tccttggtgg taaacttgat gactccttcc ttgatgaggg 6120 atttattctc aataaaacta ttggtgttaa ctgtcccaaa gttatggaaa atgctaacat 6180 tttaattgct aatacggcta tggatacgga taaagtgaaa gtttttggtg ctagggttcg 6240 tgtagacaca actggcaagc ttgccgaact tgaacgcgct gagcgcgaga aaatgaaggc 6300 taaagttgaa aaaatcaaaa gtcataatat taattgcttc attaaccgtc aactcattta 6360 caattggcca gagcagctgt tcgctgacgc tggtattatg tccattgaac atgcagactt 6420 cgatggaatt gagcggctgt ctttggtcac tggtggtgaa attgcttcaa cttttgacca 6480 tcctgaactt gtcaaattag gtcactgtaa gaaaattgag gagatcatta tcggtgaaga 6540 taaaatgatc aagttttctg gcgttgaagc cggagaagcc tgcaccattg ttttacgtgg 6600 tgccactcat cagttactgg atgaatctga acgagccatt catgatgcat tagctgttct 6660 ttcccaaaca gtcgctgaat ctcgagtcac tttaggagga ggttgtgctg aaatgctaat 6720 ggccaaggca gtggaagaag ctgctaccca tgagcctggt aagaaggcag ttgctgtttc 6780 tgcttttgca aaagcattat cacaattacc aactatattg gctgataatg ctggctttga 6840 ctctagtgag ctagtagctc agttaaaggc agctcattat gatggcaacg atacaatggg 6900 tcttgatatg gatgaaggag agattgctga tatgagagcc aagggtatac tcgaggcatt 6960 gaaattaaaa caagctgtag tttcaagtgg atctgaaggt gctcaacttt tgttacgcgt 7020 tgatactata ttaaaggctg caccaagacc ccgtgaacga atgtaatggg catagtggtt 7080 aacaactatt tttttcaaat aaaaggacat tcttactagt acttaaaaag attagaaata 7140 aaaggaggcg attacattgt tagtgtgacc aaaatttaat taaggaatgt aaatgtatcg 7200 agaaatttgg cttgttcctt cttgcaaact tgagttgact tgtaataaat gattaaaaag 7260 aaaaagttta cctcgtagtg actatgagga gatagcatct aaatggaaaa atagccaaag 7320 aaatcttcgc aagatctcaa gcatttcgaa agaaaatatc cccatttcat actcatggaa 7380 ttgatgcaac cggggatgaa gtttcatact ccaagtaact cgtaaaataa aattaataaa 7440 gcacccaata gcgtaaataa acatagggaa ccttttatga ttaatgcttt tgtgaaaagg 7500 aaatcggatt ctccagtcaa tgaagacgtc ccataagaat gtataagcag agctcaggag 7560 agccgaaaga atccataacc aaaataaata accgtgtcca gatgtcaacg taaatttagt 7620 ttgctttgca tgaatgatag cagaaagata tattaccgga agagctgttg catgttttaa 7680 agcgcttagc aggttaattt tgaatgtatg ttttctacga gataacccgt aatgtaagca 7740 ttgaagtatt gcaacaatga aaggataggc cattgctaga ggaacaaaaa aagtgccatc 7800 gcattttaga tcaggtctaa gtgtaaattt actaatatga ccctgtaaga cacaaccaaa 7860 aatgtaaaaa tcaccaagtg ctttagcata tgatgtgaat atttcagaaa caatgaaatc 7920 tttataaggg gaacgaaaat ctgcttgaaa aaacaaaaat acgcgaatta tgcttttcct 7980 caacccacgt tgagaagacc ggtagcgcca tggaaaggga aaaactatta aaataaaagc 8040 cgttattacc cagagaagag gataaatagg gtgagaataa aggccaccaa tgtctccttg 8100 agttttcttt aaaaatagaa taaacccagt agcccaagaa atagacagta tagcagcaaa 8160 gcaatatcca gcatgaaaat caactgggct aactaaattc gccttgaatt cagtattctc 8220 ctcaagatcc gtgtgcctgt tagataaagg aatttgaagt aagtgatacc attttgaatt 8280 cagagaacct cgtggattgg gagaaattgg ttggtaccga ttcaggatgt aaattaaatg 8340 ataacaaact gaccataacc aggtacctaa agaatagaga ttgttagtat tagtaaattg 8400 aaaatcttaa gttcataccg actataacca gaagacctat acgaaacgga agcgctaatt 8460 tgtggtgcaa gggaaactcc acgacttcca aatccatctt taagccgtca ctaggctaga 8520 tgcataattt aaagtatttg aagaatgttt tattatcttc caatacaatt tttagcggca 8580 ttaaatgctc aggtagatgt gagaagggag gaagagttcg gtaccaaatt gcgtagtcgt 8640 gcacggttag catgcgcatc aagctaccaa aataagtatc taagttgtgg gaaacaaaac 8700 agatgtaggc ctattcggtt gtttaataca agtgatcaac ctaatgtgag attgaagaaa 8760 tgctgtgcgt agaattacag attatcgttg cgatttattg cactagatat tcaacgttgg 8820 atattactat aaaactcagt attatcaaaa ggagttttta ataaaaagac aaaagaatat 8880 taactgaagc taagataatt aattcctacg gtagtattgc ctacctgttt atttctactg 8940 tcctttaaaa taaattatgt atttcctaca ccaatcctga gagtaaattt tatgcatatt 9000 gtgaaagcct agcagatact ttagggaatg actcaatcac gaaggatggt gaagcccgat 9060 ttgagtatgt gacaagatgc gaaactatat actgaattga agtatcaaca gatggtaaaa 9120 tttctgacca aggtttgggt ggatattcat gaaatataaa tttattccaa tctgggaaag 9180 tcgaaagttc cttaaaaaca gttagcaaaa tctgcatgaa accctattat ttaaaaaaaa 9240 agtctaaaat gttttgtttt tgttcaaagg ctcagatata atgttaaaga tttgaaactt 9300 acaggccaca tgcttggatt tggagtaccc aaagtttgaa taatactgct tgttaacctt 9360 aattcactag gccatccttc agaagatcca tcgtcaaaca aagcttgatt ggaaaatagt 9420 tcagcgatca gaatgccaaa tgtccaacga tcgacttcat gaccataaga atgacagccg 9480 aacaaggttt caattgctct ataatgacca gttccaatct aaaaaaaacg ttagaaatct 9540 tgcaggttcg gcaaaatata aaactctctt taacatactt ggggaatgag ttcctgcact 9600 tcttctcctg gatgctgttt ggaccaagca atactgaaat cagatagata agcggggcca 9660 ttcattgaat ccaatagtat attatttgga tgaatatcac gatgcagaat cccatgcttt 9720 tctaggtatt caagggcgct acttatttgc aatacgatct tgcattttgt atcaattgaa 9780 atttcatcca tcacatctga tagaacaaac gatttaaaac tcgttataag gtaaacggat 9840 cctgcttcat tgtctatgaa agagtccact atcctttcaa tgtgtggatg gcctattgac 9900 tctaaaataa gcttgcctct catggcatcg tgaggtggcc ttttaaatac taaaccttga 9960 actttaataa catatagttt tttgctattc tttctttcac ccacgaacac ttcactaata 10020 gtgccatccg tcaggtgcct tatatcagtg agccacggaa cgaaatgacc gactgatttc 10080 attaaattta taaattcaat cgttcctgat tgatttcact tgaaatttta agcctatcta 10140 acaaaataaa aaacagctaa aacgttgtaa tataaaactt tgaaaattac ttatcgcaag 10200 gtgttttacg caatatgttt ttctttttat gcaatgtgtt tggaggtgag gcttactctt 10260 tttacaaact ttaatgagag cagacatata gatatgtact ggcggtgaag gatggccacc 10320 agatgaaagc ctaactgtga tctcgcatga tgatgctaaa aagatattgg ataatgcttt 10380 taaaaaaata taaatagata ccattcttat atgtacttta tacatttgta gtacacttat 10440 aaagtcagag tatgaatttt tgtagtaagg aagaatacta agaattcttt ttttattttt 10500 attttttttt cgctttgttt gcttgaatga aaaaaatatc tttgtgataa taagtgtttt 10560 aattgtttta gagatcatat atgtgtcaaa tgcgtctaca ttaccttact cgaattgtca 10620 aaaatggtga gatgtatagg tttaatcttt tactacttta tctgtttcca aaaatcgctg 10680 ctgttatagg aaattagaaa aaatattaat ttattaaaga aatattaata atgattgtct 10740 atgaaatgtt ttacgcaatg atgtttcgag attattactg acagtgtcaa aaaaaaaaaa 10800 aaaaaaaaat agttaaatca agaactgttt ctcagtaaca gcttaaaaaa atagataaat 10860 aattttatta aatattttaa ttcataattc tacaaacatg aaagaaatta ctcgtgcaaa 10920 accattaata attgaactga gtcaaggtaa ccttaaataa gctaggttat gattgtcgcg 10980 caagtgtttt gttccaaaga aggtaataag cttagcgaaa cgaaaacaat cctacgttgg 11040 ccttttataa tattaattac ggtgatttcg tacgggcggt aatatttttt ttgcgtattc 11100 caacggaaag cgatattgcg gtaagcttta tggcagacca ctaacgctgt atcttccttt 11160 tgcaacatta gttacaatgg gaaagaacga gcagaaagac ccaaacgtgt acttttttgt 11220 accaaatttg attggtgagt attattcgga agtcttgtta cagcaacaaa gctatgttga 11280 gcaaaaaggt ctacatttcc ttctttaatt atgtcttacc cggaaggttg gtcaaagcct 11340 tttcgaaatg atactttttt ttgatatttt tttcctatca gctttttaaa gaaaaaaaag 11400 gctgtatgct ttctacattt gttttgccat tcgatgtaag caattgagcc tacatagaat 11460 tcatgttgct caaagcacca actgaaccat attttaagaa atatgcgagt taaattttta 11520 aagctgtcaa atgattttcc tttttgctct gggcaagcta tgagcggagt attggatact 11580 ttgtatgctt tttcggaagt taattaaaat aatgaatgag actttagatg tgcgtaaaat 11640 tatttgttgt gcttaataat tttaaggtgt tcttagactt aacagattta cttacccttt 11700 tgaaaataat ctattgcgtc aagtcaagtt atctctatta taaaagcatc attttcgtca 11760 cttttcaaaa ttactaaaac tttgtgaatc attatctttt atggcctctt ttctcaatat 11820 gctgaaatta gcgctggact ttcattctta taattgttca gtattctgac tctttgttta 11880 ggttttacta gggttttttt ggtacttatt tcgttgtact ttatgtcatg gcacccaaat 11940 tattgtacta ttgtgtattt atactcaagt ttacttgacg cttttgatgg ttgggcggcg 12000 cgcaaattgc atcaagccac caatttcggt gcaattttgg atatggtcac agaccgatgc 12060 gccacctcgt gcttgctttg ctttttatgt gctgcttatc caaaatatgc tataattttt 12120 caactgttag ttagcttgga ccttgccagc cattatatgc atatgtacag cactcttcat 12180 caaggtgctt cctcacacaa aacggtaaca aagaagcata actggatgct gagactttac 12240 tatggaaaca ataaagtttt attcatcttt tgcgctgcta atgagatgtt tttcgttgct 12300 ctttatttac tatcttttac cccacgtact cctcccaaac ttggctactt accagttcct 12360 tccttcattt attcgactgg agagctccct ctttcctatc cgacccttct agccgtttta 12420 tgtggtccta tttgccttgc caaacaaatt attaacgttg ttcagctggt gaatgctgcc 12480 aatgccttgg ttaaaatgga tgttgagcaa agaagggctg caaagaagct tcaataaaca 12540 cagggttatc ctattttcat attttctgtt taccaaattt tctattttta atcaggatgg 12600 tttcaatctg aacatcctcg accttagatc tgcaagctta ctttgtgcat tctctttgat 12660 tttacctctt ataattcaat accttttttt tgacattttc tctttctaaa agccttaatt 12720 ctattgggct aagcactttt gtgttaagct tagcctttgg gattattttc tgtcaccttt 12780 aaaagcttgg ttggagtgat tgcactgatt aataaaaaaa tgcatccaca acgtgaagcc 12840 attcgtcgaa aagcttattt agaaatagaa tgctttactt atttaagcga tataactttc 12900 actttacttc aataaattta atcgttcgtt gcattaattt aaaaacattg tttatgataa 12960 aaaaatccta tttaaatgta catagtagat ttttttttaa aagataaatg tatgtgtgta 13020 ttaatttacc cataaataaa gcgtccctca aatcttcacc ctttttacac gttccatgtc 13080 agttacactg gtctcagatt ttacgttttc tccatccaac attctatttg tccgcaattc 13140 atgcttagcg tgcttgctat ttgattttga aacatgtttt cgttttttat cgccgttttt 13200 atttgatttc tttgaagcct aagtatgtta gtcattgccg aattttgaaa attctgtgaa 13260 gtaccttatt taaactgtga gtcttttcag ataatgcgag atcaagaagg cgtttactta 13320 atgtttttaa ttgctcagca ttcgggttga tgggaataac gtctttttcc tcgtagacct 13380 gattacactg atgttgtgtt agcaataact caagggttgg aaatgctttt cttagctatc 13440 gatagactta cttgaaaaca cattttctcg ccaaactgct tcaaggcaga gtattcaaat 13500 acatgaccgc aaggcactat gtaggcgaat tggtatgtat cagacattac atgtcttgta 13560 atcgggcata accatagcac tttaccggaa tcatccagct caacttgaag ttgtaccacg 13620 tctttcagtg attttatatg agaagggctt ttcggaacac ttgacctatc taacagcatt 13680 tgtaaaatgc ttgctttgtt atacagtttt cctaaaccac acgatacaat tggagggtat 13740 aagggctcat ccgtaatggc acactgagaa aattgagaag attttacaga acgtttaaag 13800 tctatatcaa gcggcggtac tttgccaggc tctttcacta attcgtttcg ggttggtaat 13860 gatcctccta aaacatgtta aaatttagaa gcaaaataaa cgaatcctac cgtcatttcc 13920 catagtttac ttgtgtgtat taaatattac agagtagtgt taagtaagca tatttcaaag 13980 aagcgcttac attccacgac tgcatttact gcattctact ataatgcact aaaattaaac 14040 gttaggtttc gttacgcaag atataccgaa atgtcaaata caattttcgc ttcaatgatc 14100 ttcgcttatt tttaaacctt atttaaattg caaacatttg tgatgggaat acgtagttgc 14160 gttaaggact tacgaaagta tacaccaaaa gcagcaattt ttcttctaca acagctggtt 14220 tgtaggtttc aactacgagt taactgcttc tttcatacat ctaaatcaat gttatatgaa 14280 acattttgtg aaatccgaaa cctcttactc ttagtatcca gttgagttcg aaaattggta 14340 ctgagtagct attagtattt taggcccctt tacttacttt tgtttttgtt aacttagatt 14400 tcggaccctt ttttttttat tcatattgaa ccttttcctt tttctttttc aggtcgtgtt 14460 aaatgtcgaa aactgttaat tttagggcaa caaaaaattt ctatttacaa tttgtgagcg 14520 tcagttctcg ggatacatct tgtattccct gcatccactt attttttgat tctaagaggt 14580 atgtatttgg aagcgtaggg gaaggttgtc aaagagctat actctcccaa cagcttcgat 14640 tatcaaagat taaagatgtc ttcttaatgc aaggatcttc aatatcatca ccagatacat 14700 atgattcttc ttcttcatcg tctactacct ctgtttctga tatgctacag ctggatgatc 14760 gggacaaagt tattgtatct gaacgtaata gtatgtgctc gactgtaaac tatcctacat 14820 ggtgggattc ttgtggtggg tttccaggta agtgttaaat atatttaata atttctgaca 14880 ataggctttt tgctgtctct caatgatatt tcggaacctg gggaaaccgg agaagctagt 14940 ccttttgtcc ttcatggacc tagtgaagtt catcagtttt tatcttcgat gcggcatttc 15000 acttatcata cgaatgtaaa tttaacggta cagggatata cttcggctga ggccccagta 15060 ttcgttgatg aaaatatttg tgtaactccg gtagttgttt cactagttaa aaattctttt 15120 aaaaaaagga agcatgaaaa cattaacaga ggtacaaatg caagaccatt aaaagaggat 15180 agagcaaata cttctcctca ttggtattct cacgtttcca atgatacatc attcgtcgtt 15240 gagaatgcaa tgtataacac tccggctcct ttggaaccag acaagccaga gctgtttatt 15300 tcttatattg ttcaatccca tcctacccca gggaaatttg acgccgcaaa agcaaaatcg 15360 cttggtatca cgaaaggatt agactgtggt agactcgctc gaggagaacc tgtaactctt 15420 gaaaacggaa aaacagtata tccaaaagaa gtgattggtc cttctattcc tggctcctcc 15480 ttttttatta ttcattgccc caacgaactc gtaattgact tggtcattga aaatcataaa 15540 tggacaaatg cacctaaacc tgtttgtgtc attcattcgg ttacaccaga agtatacaaa 15600 aatccacgtt atcagagctg gatttcttca ttcccaagtg aggtgagcca tctaattgct 15660 tcgactgaag taaacgaagt aataaattat cctaggagtg cagtcgctat tgcaacactt 15720 aatttgttag attcaaaagt ttttccttta ggctttaact gctatgaagt taaaaatgta 15780 caaaaaaaca atcgaattgc ttttgccaaa cccaaactgc gttttgcgtt tggaaaaaaa 15840 actggtattg acgattcgga agttggggtt tcgattgaag agttgaagga taaaattttg 15900 aaagagaaac cagattataa atcatttgtt gaagaagctc aaaaatatgt tagtgataaa 15960 ccaaaggcac cgagctttgc aggttctgac atccaaattt gtactcttgg cactggatct 16020 gcaatgcctt ctttatacag aaatgtttca tctacttacg ttagaattcc cgttgacaaa 16080 aaatgtatgg aagactcagc tatcagtatg aaaaacatac ttttggactg tggagagggc 16140 actttgggac gtctatcgag gcagtatggt gacaatttaa aatacgaaat agcttcttta 16200 cgatggattt atatctccca tatgcatgct gaccatcatg ctggtgttat aggggtttta 16260 aaggcttgga cgaagtactc agatggcaga tcaaagttgt ttataacagc acctccacaa 16320 tttgaatttt ggctactaga atactcaagg attgattatc taccattatc caacatcgta 16380 tttatttcca atagtgcttt acgtactgac aggaagccgt ctgctttgga atcctctagg 16440 ttgtcttctt tatttaaaga atttgattta gtatcttttc gaacggttcc tgccatacac 16500 tgcccgtatt catattgcat ggagattact aattccagtg gttggaagat cgcatactct 16560 ggagatactc gaccttctga ggattttgct aacattgcca aagactcaac tttattaatt 16620 cacgaagcta ctttggaaga ctctatgcac gaaattgcaa taaaaaagca acacagtact 16680 tactctgaag ctttagaagt ggccaaaaaa gctggtacaa aaaacgttat tttgactcat 16740 tttagccaac gatatcccaa attaccagac attgatattt cgacagaaga cttacatata 16800 gctttggcgt ttgatggaat gactcttaaa atatcggata tctcattgtt tcgttatttt 16860 ggaaagcctc tggcttatct atttaatgag gaaaatttaa aagaggagtc ggatccttta 16920 aagttctaac tacttgagct attgtctcat attatataaa ttgggtctca ggcaagtgat 16980 ctctgttgtt taatgaaatg ggcaaacctt ttcttcatta tacaattatg ttcataacaa 17040 aatacttcag acttcaaaaa aattgtcaag gtaatccgta tctattaaaa tagtcctgaa 17100 aaccattaat gatctttttt tcttttattt cactgagtaa ctactattta acccaaggac 17160 caaaatttac gagtgtaatt gacgacttaa tcaaaccttt atggaataat ctaaaaagag 17220 gacaattttg agttttaatt tatatcggat aaccaagtac tctatgcaat taaagtaatt 17280 gtagaacatg cgagttttcg tctaagaaac tgaataataa caaacgaata aacatcagct 17340 aaagcgtaac acaaaccaga aatacgagac ttccgtagat ttgtaaatta gaaagagtga 17400 aaattattga aaaacatgaa gtaaattata aatctctaag tttatccatc acaaatttga 17460 agaaattggt tgggtgaaaa agggatgcca aagggcctct tttgcagtta ttcgccgctt 17520 aggatcgtaa acgaatactt ttttcaataa atcaagcagc aaagccactt ctggagatga 17580 tactgcaaat atttgctcta gcgtttgcag agattgaaga taattaatgc tttttttagg 17640 cgtatttgac aaaggataac ggacttttcc gtcagattta aaaaaacgtt gcgatgtacg 17700 agaggaacgc gaaatcatat tcctatcaaa gggacccagg attttttcca tcatgcacag 17760 atgctcacta tcttcatggg tttgaaacaa ggcttgtccc gtgaataact caactaaaat 17820 acatccaata ctccaaacat cgcaaggata agaccaaccc aaccctaaaa taatctctgg 17880 agcacgataa tgacgagtac tcactacact ggaatggtat tcatcttcaa atgttgcact 17940 accaaagtcg ataagccgga tttcacaact attaaggact ttctgtgaat aattccgata 18000 aggtaatcga atagttcttg aggcattaga taccagaaga acattttcgg gtttaagatc 18060 ggtatgtact agtcccaaag agtgaagaaa cgcaacactt ttaaaaagtt gttgggatag 18120 catctgaata tgcttcaaag ggaaaggaat gtagttgtta ttctttaaaa aatcaaagac 18180 actccagcca aaaagatcag tcacaatgca gatgtgcttg cggtaatcga aataatcgcg 18240 taactgaatg cacttatttt catttgtcgg atcactatga gctatagttt gtaaaactct 18300 taattcaatg agactagctt ctctgtactt tggaattgct cgagtcacct tgatagcaca 18360 atgtctacct gtactttgat cgtaacactg gataactttg ccaaaagtac cgtgcccaag 18420 caaacgaaca actgtataac ggttggcaaa tttggagtta ggtacaacct tgtaatgacc 18480 gtcatcatca tcaaaagttg atggatcaaa agcggtagta tcatgcacaa caggaacatt 18540 tacgcggtcg acttttttat atgggggcca tgcagctcgc ttccttttct tcggaggtcg 18600 ataatcggaa atagatacag gagtgataac ttgattggca ttagaagccg gttgataaac 18660 gtttgcagaa ggaggttgga aagttggttg agtcatcgga agccatacgg ccagcgttgg 18720 agataatggt acagcggtat gattgttaat ggaacttggg gtgacggaat aatttacact 18780 tttatgttga gacgattgcg aggaaggagc gatagcagta gccggagcta gctgaggagg 18840 gttagaagga caatacgttg caggacatag tgggggagga taagaggttg gagacgagta 18900 aggatgatta tggatgggat gtggaagcct gttcggatgg acttggagct ttggtaaatt 18960 agggatcact ggaggtttag aaattggttg gtgaggtaaa ttaggagagg gaagcgaaac 19020 cgggtaccag tgtgaaggaa cttgagggac aggaggcggc cgtaaaacag gttgacatga 19080 aacaggtagt ggattatgaa ggggaggatg atgtgaatgg ggaaatggcg attgattatt 19140 tgaacacgca tgatacgatg taggagactg aaccatatat gaaggatggc tggcgacatc 19200 atgcggtaat ggaacgacgc cattagcatc caaccatgga tcataggatt gaggaagaga 19260 taccgagtta gttgatggat aaacagcatt cgcaccattg atagggactg ccacagtgcc 19320 agtggtagag ggtgatgatg atgagggagg ttgcggaggt acgaaggatt gtaattgatg 19380 aacagaaaaa ggaggcggta aattaggggt aagccgtgga gaagctgagt cctctataac 19440 aatgacttct tgtggaacac catttttata aaagtcctgc caatcaggcg catgatttct 19500 acgacgtttt aaggaatgca ttttacaata aaaagattcc gtctaagtca tgcgagcaaa 19560 ttggtaaagt gaagaggtag aagacgtcga aacctgaaaa aagggataag tatcttttag 19620 aattatgcaa aaccagaagc aaaaatgatg aaaagagata ccaaccaccg aaaataagtg 19680 tttctcaaac aataataagg ggaaaagttt ccttgttcga agtcaccaag cgacaaaagc 19740 aataaaaaac cttttttttc gactcgtcga agggtaagaa caaaatagaa aggcggaatt 19800 taaaaaataa aaataaaaaa tggacgaatt aaagcaatag aactgaactg acaagcattc 19860 gacaattggt gttggaccag aacagctagt tcatcaagaa gcagagaatg ggaggaagaa 19920 tgagcaatca agttaactgg tacacctact tcgaaagagt ttcaaaattt gaatgcaatc 19980 acgaagaaag aagttaaaat tctcgacgtt gtaaaattgc aaggccgtcg atcaaacgat 20040 aaatcagcaa agaagcggaa aacagtgaga aagtgaactt gaaatatatt tatcaaacca 20100 aatggtttct tatatcaggg agaagaaagc cgttttctca gaataaagac aattgacgac 20160 aaccactaaa cccctttctc aatcaaatgt agggtgcaac agtaaagaga aacagcaaat 20220 gcaaaaaggt atcggagaga aataaatatc tacaataccg gagaataagt atgccgaaca 20280 cggagggtct gtaaaggcaa atcaaacacg aaaaaacgat aaacaccaaa ccttcaatca 20340 acaactagcg gaaacctttg tatcaatcgt attgctttaa agtaatgatg ttccaaggca 20400 atattgtacc atgagacaat gatgaggttt ttgtgtttga gggggtgcga ttgcgctact 20460 accaaaattg atcaatgtcc aaatcaggcg gattagtaat ttggataaaa caaaagtata 20520 aataaccccc aaaagaatcg gcaattacca gggcagtttt caaaagcaca caaagtcgac 20580 gacaagcgat gtagctgtag tacgaaagtc tacctaacaa aatggtagat cgtagatgga 20640 gaaaagcaag tagtgagtgt agtaaattga agaatgaagt atatacgact cttaataagc 20700 aattttcttt ttctttcctt caatcccaca gaatgtaatt ccaatggggg gggggtaaaa 20760 caacaaagca atgtcctaat aatacaactg ctaagaaaac tagtaattga ggatagaaag 20820 gataaaagaa aaagcctcaa gccaattcga gggatgtgga gaaagtaaaa aggaattagc 20880 aagagtttgg ataataataa gttgcgtttt ctttggtaaa gccacttaga aaaggtgaaa 20940 tttgcatgag ataatcatgt ttgtgagacc ggaacaacat cattgttatt ctatccttaa 21000 aataaaatag ctggaaaaaa ttggccggac gagggaacaa cccaacaatc accatccagg 21060 cgcgttgcgt ttggcacctc cttcctatga aaaagtatac acattccaca acaccatgtg 21120 cgcagtatgc aacgtaccta gccgtcaccc aactatagcg taagagacgc ttgctactct 21180 gaagggctga gatctacgaa aaccgccatg gccgtagagg cagaggcgct gaatgaattt 21240 tcattaattt agatcactaa tcatttacca ttcaaatgcc gctccattca actcaaccat 21300 attcacttaa ggagttttcg taagaaatgg cttatcattg tcatcatacc attcaaacat 21360 caatacacac cacacataca cacacacaca aatgtacaca agcatgcaca ctcatacaca 21420 tatataaacg catgtttaca taaatagtta taaaatttac atatagtttt acgcataaat 21480 aatgcaactg tcattctcac catctctatc caactctacc taccatgtac tatatactgt 21540 attatacaat gaatgctata tgcccgctta tactgtagct gccttgtcgc ccgccccatt 21600 tgtccatggt atagtattcc gcacaattct ttaccagaat agaaatgaaa tatagaaaac 21660 atgccttttc agaagcgttt ctcacacttt caacaaatgt cgtccagccc atctgccaaa 21720 ttctcttacc aaactagtct tgattatggc catccgtcct cggtaatcga atatttcgtc 21780 caaacagcga cgcttggcca tcaaaaaatt tagtggatga caataatcta tgtaacaaat 21840 aatacgataa aattgccatg atgagtaaca aaacaacaaa ggcaataatt catcaactat 21900 tgaataatca tttaatggtc gcgaaaagga aacaaatata attttctaca atcaatcatc 21960 tacaatgact gatgttagag cttgaaaacg ggatgtgaaa aattcaatca acatgacttc 22020 aaatggggtg agaaattgta attaagcaaa ggaaaaaaat aggcaacaag gcatggttgt 22080 agctgcaatt aagggactaa tgtgtcgtga aactcaaaaa tgtaaaaaaa agaatgacaa 22140 tccccttgca taattgaatt acccgttgaa atttttggga aatccggtta ctgcagacgg 22200 aagttgaaag tcaactttat ctcggttctt tttttccttt tttttttttt ttgcaacttc 22260 cttaccggca cgcaaggtcc gtcgcacttc tggaccagga gtaaactgct tacttattga 22320 aagaacaaag aaaattttaa cctttcttta aatacgcttt cttttctttt tcttttttca 22380 ggctattttt ttgctcctcc cgtcatccct aatagctagt cggctttaac gattattatt 22440 ttaggagatg ctaaagtgca gattgacggt cttgttcgta atttgcaatc agtctatgtc 22500 atgatccctg acctcagtac agtggaagct gtctggctgg caagggtaaa ggctagtaag 22560 tactatcaat tatgtatgtc agttgtggat ggggaattat tattgagact ttttacaaag 22620 tgtcaagctc gagatttggc cattacatgt cggtaaagca gctgaacagc gatatgccgt 22680 tcataaaaaa gcgtcagcac aagtgaaatc aagtgtcatg acatgaaagt ctaatcggtt 22740 atttgcaaca ttaaccgaaa cttgtagaaa atgcgctctt tggcagttga aaaacgcaga 22800 cattacagat gctataaata catagtatta aaaacataat aacaaataac aataacatgt 22860 taattaatct tgctatacat agtaacatct ataaaacgca gtgtaaacag aaatcatttt 22920 gacatgaatt tcttatgtaa caaatgaatc ttccatcttt aaagggaaat ccgatcgctg 22980 tgttctcaag ttatcgactc ctttttctca tagcaaaggc tgagcaagca atcaaagctt 23040 ttgctcctag gattatctag gacgatgcaa cttcaacatt cgttgaacgg accgcatacc 23100 catttcctag gttcaggatt taagctttgt attgtgttgt gtggtagtac aattaagcaa 23160 aaaggaaccg aaccgttggg gctgaatatt gtttttcact atcaaacagg taataagata 23220 tatatgaagc aagcaactta tttgtaagcc tagctaaatg ctttatcaat ataaactcga 23280 gggaaatatt ggtagcatag tattccttta acttttcttt ttttttaaat taattttgat 23340 ttcacttttt agttaacgaa aagaattatt ttttatttaa taatggcaag cggagttgtt 23400 tcaatccaat atattacatt taccagtaaa aaaattcgat actttccctc caccgtgtta 23460 aattgctgca tttttttgca tgttacggga tgtaaggaaa taatctcaaa ccagtcatcc 23520 ttactttggt ttcctacatt taatgagcca tgccatctat cctctatttc aataccttcc 23580 ttcccatttt tttctgctaa atcgatatgt tgttttttaa atactctttg ttattagtac 23640 tatatatgca ctattgattt tgctagcaat gtattgtatt atttgtatgt tttgtagaaa 23700 ataacctact cgccaaccca aaaataccag ttgtttccga cagcgtcatt tattcatcac 23760 acttttccga aaatcggctt tacaagtccc gagtaaaagt gaatcaagaa acagctacca 23820 tgaatttgat caacgatttt gagtaaccac agaaaaactc agtatggccc attacggttg 23880 gaatgggtcg ttgttatgaa tgccattttc ttgttaccga gcggcaaact ccaacagtat 23940 attgttttgt agcatcgcta atgaatgatt cgttaagttt gttttcgtgg aatttcatgc 24000 tcttctttta tacccgaaag ccggatactc gtcgatatac tagatgtgta gtgagttaat 24060 taattagcca gaaattagtg aatgggagag atttttaaaa tatcaagatt gatcattact 24120 aatcatcttt catctttcac aatacttgtc atcgatgatt gatagagatt gccaagagac 24180 attaggtaaa ataaaacgta acagttttga cgatctgctg atttgcttga tgtcaacctt 24240 gggtatgttt tcattaaaca tgattgctga tgggtttcat aattcgtgaa aaattgataa 24300 agcacttttc cttatcatct acacataagt gaacaggcaa atcaatccgt attgtctcct 24360 caacatacgg aatgtcatta aaaccggtaa actgtactaa ccggtgatta cgggataata 24420 aaaaaccact tcattcattt caaaaactgt tgatatagta ttctgtatga tttcaagaag 24480 ataactcttc ggtgacttgc tgtttattgc tcacctggcg attctaattc cttttatttt 24540 ttatcctgat acgtatgtat ttgtttttcc ctctttagaa taatattcat taagcttgaa 24600 taagcggtta ttagtttgca aatgattcag cagctatatg tgagtttgcc ctttttcact 24660 tgtctacaga gtcgggaatt gacttgtaaa acaaaataaa tggaatattg caaatgtatt 24720 ctttttgcct tgtgtttatt taggagtagt attgcggaaa cttgttttca gaaaacaaag 24780 tagcgcttat gctcggtaac tacgaaaata cgaatttttt ttccaataaa ctagtattta 24840 ttaagcaatt gcatcttcca ttaaccatgt catttccatc aatgtatagt tgtatgtaca 24900 ccatgtattt acgaatatta tccaatttaa cgtactttac agtattttgc ttataaatgt 24960 ttaccgtacc aactcagcgt tcttcataat ccagttctat atgcactaca aatataaagc 25020 agccactgtt aatttcagga ctcattcttt aagcttggat cgacaagtag tttctcctga 25080 gattctcact gtaaagtagc tcacttaaac cttaggtcag aattatttct tggttcgttt 25140 tgttttaccc tcttccatcc catgtttatt tatttatctt tgtgaactta ttcatatttg 25200 tgtatcagtg attgacgact aaatattgaa ccaaagcaga acctacctca ttcttataat 25260 acccataaaa atttatttct cgctttattc atttcatttt tatgaagcga ttgttaagcg 25320 atctttaccc actattattc atcaatgcta gttcataatt cttttgtttc aactttttat 25380 cttattattt aattcctaaa tttttttttg gtccaatagg ctgtcatata ctcaaattaa 25440 tttcctcaaa gtcaacggat tacacccata atgaagttct atattgacga tctacctatt 25500 ctgtttcctt atccacgcat ctatcccgag cagtatcagt atatgtgtga tttgaaacat 25560 tctttggatg cgggaggcat tgcgctctta gaaatgcctt cgggtactgg aaagaccatt 25620 tctcttttgt cccttattgt ttcatatcaa caacattatc ctgagcatcg caagctcatc 25680 tattgttcac gtaccatgtc ggaaattgat aaagcattag ctgaattgaa gcgtttaatg 25740 gcgtatcgga cttcacagtt aggatatgaa gaaccatttt tgggtctcgg actaaccagt 25800 cgcaaaaatt tatgtttaca cccttctgtt cgtcgtgaaa aaaatgggaa tgtggtagat 25860 gcccgttgtc gctcacttac ggcgggtttt gtgcgggagc aaagattggc tggtatggat 25920 gttcctactt gtgagttcca cgacaatttg gaagatcttg agccacacag ccttatatct 25980 aacggtgttt ggacccttga tgatatcaca gaatacggcg aaaaaactac acgatgcccc 26040 tattttactg tacgtcgtat gctaccgttt tgtaatgtta ttatttattc gtatcattat 26100 ttactagacc ccaaaattgc tgaacgagtt tctcgagaac tcagtaaaga ttgcattgtt 26160 gtttttgatg aagcacacaa tattgacaat gtgtgtattg agtctttaag tattgatttg 26220 acagaatctt ctttgagaaa agcttcgaag agcattttgt ctcttgagca aaaagtcaac 26280 gaagtaaaac agtctgactc aaaaaaactt caggatgaat accaaaagct tgttcggggc 26340 cttcaagatg ctaatgccgc aaatgacgaa gaccagttta tggcgaatcc cgttttgcct 26400 gaggatgttt taaaggaagc tgttcctgga aatattcgac gagccgaaca ttttattgca 26460 tttttgaagc gttttgtaga atatttaaaa acaaggatga aagttttgca cgttattgct 26520 gaaacaccaa cttctttttt gcaacatgtt aaagacatta catttataga caaaaagccg 26580 cttcggtttt gcgctgagcg actcactagt cttgttcgtg ccttacaaat ttcactagtt 26640 gaagattttc attctttgca gcaagtagta gcttttgcga cccttgttgc tacttatgag 26700 cgtggattta tcctaatttt ggaacccttt gaaacagaaa atgctacagt tcccaatcca 26760 atattgcggt tttcctgtct tgacgcctca atagctatta aaccagtttt cgaaagattt 26820 aggtctgtga ttatcacgag tggtacttta tcccccctcg atatgtaccc caagatgttg 26880 cagtttaata ctgttatgca ggaatcgtat ggaatgtcac ttgcacgaaa ctgtttcctt 26940 cctatggtag ttactcgggg tagcgatcaa gtagctattt cttcaaaatt tgaagcccgt 27000 aatgatccta gtgttgttcg caattacggt aatatactgg ttgagttttc gaaaattaca 27060 cctgatggct tagtcgcatt ttttccaagt tatctctacc ttgaaagtat tgtttctagt 27120 tggcaaagta tgggtattct agatgaagtc tggaagtata agttgatttt ggtggaaaca 27180 ccagatcctc atgaaacaac tctcgcctta gagacttacc gggctgcttg cagcaatggc 27240 cgtggagcag tattgctgtc agtcgctaga ggaaaagtct cagaaggagt ggattttgat 27300 catcattatg gtagagcagt aatcatgttt ggtattccgt atcagtatac tgagagtcgt 27360 gttttaaaag cacggttaga atttctgagg gatacgtatc aaattcggga agcagatttc 27420 ttaacatttg atgccatgcg gcatgctgcc caatgtttag gtcgcgtttt gcgtggaaaa 27480 gatgatcatg gaattatggt gttagcagat aaacgatatg gtcggtctga taagcgtaca 27540 aaattaccta aatggattca acagtatata accgaaggcg ctacaaattt aagcactgat 27600 atgtccctcg ctttggcgaa aaaattttta cgaactatgg cacagccttt cactgcgtct 27660 gatcaggaag ggatttcttg gtggagtctt gatgatttgt tgattcatca gaagaaagca 27720 ttgaagtctg cggctataga acaatccaaa catgaggatg agatggatat tgatgtggtt 27780 gaaacttaat agaagccatt tgtaaaatac tttgattcta atcatcttta ctaaggcaat 27840 ccaaaactca tgaacacagc gatgaagata tttggaagcg aatggctaac ttttttgtag 27900 gtgtggacaa tgtatgtatc aacttgtatt cgagagttgt atagtggaca tttcaatcgt 27960 catcacgata cgcatgctac ttacgaattg ttttaagatc gcagagcaga gaaaaaatat 28020 tatttacact cagttggcaa ttaatttgcg agtcgctaaa ttcgaagtac tttaaaattt 28080 ttttagagac tgtgttcaaa taaaatcggt ttcagttgtt gtaatgcttc ttaaattttc 28140 catcccatca ataacaatcc agcgtttcaa agagtgatta ttggcaattt catgctgcta 28200 tggaaattaa gcttacatta agcgagctag ttaaaatacg tgatgcagta attgtaagcc 28260 tagttatata aacaaaacat ctgtttatca tttagataca taaaacaaaa gtttacatat 28320 tcataatata ttctcataat ctaaaaaatt tccttgatag ttttatgtcg ataaaattag 28380 tctcccatac ttagttctaa ataaatgaac gttttggggt tgtacaactg attcattgct 28440 gtattctatg taatatataa atttcttgaa aataaaaaat cttttggttt tacggattca 28500 cggttggctt atacgtaatt gccaagcaca tataagatca atgatggttt ctttaccaaa 28560 ctactgtata aaaaaattac tctagcacaa aaaggatacc gctttcagga attcttaaat 28620 atagaaaaaa aaataagtgt agcttattgc aagggttgtc tctagtcacg ttggggtagt 28680 cagaatcctg tcataactac tgctttgtat ctttgattag caaagtaact tattgaatac 28740 agtcagctgt caaattacag aaaaagaagc aactttaata gtatcttaaa tgatataatc 28800 ttcgatacag gtttctttga gaatttggcc aatagctaga aatgtttaaa cgacgtcgaa 28860 atccaaaagg tcttgtgttg aatcctaacg cctctgttaa aagctctgat aatgatcata 28920 aggaagagtt aattaacaat caaaaaagct ttgaatccaa tgtcgaagca tttatggagc 28980 aatgtgcgca tatgaatcga cgcccagctt ggatatctga tttggacaat agcagtttgg 29040 aagtagtgag gcatttggga gagggaaatg gtggggctgt ttcattggta aagcatagaa 29100 atatttttat ggctaggaaa acagtttatg ttgggtcaga ctctaaactt cagaagcaga 29160 ttttgcgaga gttaggtgtt ctacaccact gtcgttcacc ctacatagtc ggtttttatg 29220 gagcttttca gtataaaaac aacatttcat tatgtatgga atacatggat tgcggatcgc 29280 ttgatgcaat tcttcgggag ggaggtccta ttccgttaga tattctagga aaaattataa 29340 attctatggt gaagggtctc atttatttat acaacgtttt acatatcatt cacagggatt 29400 taaagcctag caacgttgtc gtcaactctc gtggtgaaat aaagttatgc gattttggag 29460 tttcaggtga actagttaac tcggttgctc aaacgtttgt ggggacttca acttatatgt 29520 ctcctgaacg aattagaggt ggaaaatata cagtcaaaag tgatatttgg tctctaggaa 29580 tcagcattat tgaacttgcc acccaagaat taccttggtc gttttcgaat atcgatgatt 29640 caatagggat cctagatttg cttcattgta ttgttcaaga agaaccacct agacttccat 29700 cttcgtttcc tgaagacctc agacttttcg ttgatgcctg tttacataaa gaccctacac 29760 ttcgcgcctc tccacaacaa ctctgtgcga tgccatattt tcaacaggct cttatgatta 29820 atgttgacct tgcttcttgg gcctccaact ttagatcctc gtaaatgtgc aaaggacgca 29880 atggatacat aaattatgtt agacctttaa acatcttgtc gtcaaaaaga aggatttcag 29940 aaaaatcttt ttaaattaaa ctttgtcatg aaatggatat ttttggttct aaccacacct 30000 cttcaattat agtggtacaa cacaatgtgg agaacaatga gattttgtcg ttgacgaata 30060 tttccgcttt tttcttaata caaagcatta ttagatcggc cataaatagg tatcatattt 30120 tgtttatcaa ttttttactt cattaaagtg ctatgtaaat gccctctttt tttggttatt 30180 ccattattaa ttatcattac gactgtgttc aaatgtaatt ctcggtacac tgaattgctt 30240 tcgatttaag tcaatgaatg ttttttttaa ctacttgagt tacagcgtcc acaatagtct 30300 gagttaagtt ttacccaagc aagttaatca gagtcctgca tgtcaaatcg cacaacttct 30360 aataaaccag atgataaaaa attaaagctt aaagcccgta gtttgcaaat attacaatta 30420 atacataaac cattcagatg taaaatttaa cgaagtaagc aattattatt tacttgccag 30480 ctatgcagtt tggtatctgt gttaacgata cgtagactcc aaagagtttt ccttgtgacc 30540 tattatattg caatatacag gtaatatttg tagctacagg ttgtatgtat tatactatct 30600 agattatatt gttacctatc attaatttag ctattaactg aactgaggaa tgaggatcaa 30660 cagtagctct atttacagta ttcaaaataa tataaatttt taagagatta ttattaagat 30720 cacctaaata tcgtaacgta cgtgtacgat gaataattag gacatgtgac atatagtgat 30780 aatcaacgta agtattatag cgtagcgtaa tattactaac ggcgaactgc gtagctagta 30840 tgctatttct gattcgaaaa accactgtaa taagtagcga agtactttaa gttttcattt 30900 cactttaaca ccaagctttc tgggttttta cttgtttgca agacgcagca aaagatttat 30960 cagtgattag tgctgtagat tgaatttagt tagccttgtc acttgttaac attaaaaaat 31020 tttgttgcaa tccgtttcac tacgattgta atttttaaca agtgttcatg acttcgttgc 31080 cagaaaagga tcagcaaggc gaagttagtg tttcaggtaa gaagttcgag gtaataccga 31140 ttaatttttt attaacagaa tataatttta gaaaatcaaa agaagctctc agaggaatgg 31200 g 31201 //