ID SPAC1B2 standard; DNA; FUN; 13599 BP. XX AC AL133157; XX SV AL133157.1 XX DT 18-NOV-1999 (Rel. 61, Created) DT 18-NOV-1999 (Rel. 61, Last updated, Version 1) XX DE S.pombe chromosome I cosmid c1B2. XX KW cell division control protein nda4; crm1; KW cytochrome c oxidase polypeptide vi precursor; GNS1/SUR4 family protein; KW intron tRNA leu; nda4; tRNA LEU. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-13599 RA Barrell B.G., Rajandream M.A., McDougall R.C.; RT ; RL Submitted (18-NOV-1999) to the EMBL/GenBank/DDBJ databases. RL ac.uk XX DR GOA; P14068; P14068. DR GOA; P41389; P41389. DR GOA; Q9UTF6; Q9UTF6. DR GOA; Q9UTF7; Q9UTF7. DR SPTREMBL; Q9UTF7; Q9UTF7. DR SPTREMBL; Q9UTF8; Q9UTF8. DR SWISS-PROT; P14068; XPO1_SCHPO. DR SWISS-PROT; P41389; NDA4_SCHPO. DR SWISS-PROT; Q9UTF6; COX6_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1B2 . XX FH Key Location/Qualifiers FH FT source 1..13599 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1B2" FT /map="I" FT misc_feature 1..4715 FT /note="nominal overlap with cosmid SPAC1805 S. pombe FT chromosome 1" FT tRNA complement(70..167) FT /note="tRNA Leu anticodon TAA, Cove score 44.02" FT intron complement(114..129) FT /note="intron tRNA Leu anticodon TAA" FT CDS 1817..5053 FT /db_xref="GOA:P14068" FT /db_xref="SWISS-PROT:P14068" FT /label=crm1 FT /note="SPAC1B2.01, len:1078" FT /gene="crm1" FT /gene="SPAC1B2.01" FT /product="crm1 protein" FT /protein_id="CAB61468.1" FT /translation="MEGILAFDRELDVALLDRVVQTFYQGVGAEQQQAQQVLTQFQAHP FT DAWSQAYSILEKSEYPQTKYIALSVLDKLITTRWKMLPKEQRLGIRNYIVAVMIKNSSD FT ETVLQQQKTFLNKLDLTLVQILKQEWPHNWPNFIPEIVQASKTNLSLCENNMIVLRLLS FT EEIFDYSAEQMTQLKTKNLKNQMCGEFAEIFQLCSQILERAQKPSLIKATLGTLLRFLN FT WIPLGYIFETNIVELITNRFLNVPDFRNVTIECLTEIASLTSQPQYNDKFVTMFNLVMT FT SVNSMLPLQTDFREAYEESSTNEQDFIQNLALFLCAFFSSHLRPLENPENQEVLLNAHS FT YLLNISRINEREIFKICLEYWSKLVAQLYEEMQQIPMSEMNPLLNLSSPTSLISSNPNM FT LANLPLRKHIYKDILSTLRLVMIENMVKPEEVLIVENDEGEIVREFVKETDTITLYKSM FT REVLVYLTHLDVVDTEIVMTEKLARIVVGTEWSWQNLNTLCWAIGSISGAMNEEMEKRF FT LVNVIKDLLGLCEMKRGKDNKAVVASNIMYVVGQYPRFLKAHWKFLKTVVNKLFEFMHE FT YHEGVQDMACDTFIKIAQKCRRHFVAQQLGETEPFINEIIRNLAKTTEDLTPQQTHTFY FT EACGYMISAQPQKHLQERLIFDLMALPNQAWENIVAQAAQNAQVLGDPQTVKILANVLK FT TNVAACTSIGSGFYPQIAKNYVDMLGLYKAVSGLISEVVAAQGNIATKTPHVRGLRTIK FT KEILKLVDAYISRAEDLELVGNTLIPALFEAVLLDYLQNVPDARDAEVLNLITTIVNQL FT SELLTDKIPLVLDAVFGCTLEMISKDFSEYPEHRAAFFQLLRAINLNCFPALLNIPAPQ FT FKLVINSIVWSFKHVSRDIQETGLNILLELINNMASMGPDVSNAFFQTYYISLLQDILY FT VLTDSDHKSGFKLQSLILARLFYLVESNQITVPLYDPSQFPQEMNNQLFLRQYIMNLLV FT TAFPHLQPIQIQEFVQTVLALNQDSIKFKLALRDFLIQLKEFGGDNAELYLEEKEQELA FT AQQKAQLEKAMTVPGMIKPVDMPTMEEEEL" FT CDS complement(5851..7116) FT /db_xref="SPTREMBL:Q9UTF8" FT /label=SPAC1B2.02c FT /note="SPAC1B2.02c, len:421 SIMILARITY: LOW to S FT cerevisiae, Q03327, D8035.13P., (502 aa), opt: 381 FT z-score: 445.1 E(): 1.9e-17 (25.2% identity in 405 aa FT overlap)" FT /gene="SPAC1B2.02c" FT /product="hypothetical protein" FT /protein_id="CAB61469.1" FT /translation="MNPYRPYVVVNNVEPTFSITPEPTFETQPTISKSEIFETLRSILV FT TKYLTTFFVQPLEVAKTVCQVEEYLPKRTKIERDGKQTKEPYDEDIPDGTEQEGLSDDE FT HEIYAYFETPTTEKAVTEQLAEKLCVDASGYVTDPSNLIERSYTIHSKRFSIKSIISEL FT WEKEGARGLWKGHTISFLHNLLYSGLQSWLSATLSGALAIADPNIISPIDSVRPLLSLF FT IKSITSAISALILSPLDIARTKIILFPISSSSYLSSASETSGNSHKKFKPLTIRQCLKA FT LPFYCPSSLILPTVCYVSLPPFVSSVLPLTFRNFLGSSPTLDAMVGLGTSAVQFLLKCP FT LEMVLRRAQAQYECNLPPQTIVPVGKYTGIVGTIWCLLSEEDPGKFGIEGLYRGWRVGI FT WGMSSTLALNYISSNLREEVEF" FT misc_RNA 7574..8001 FT /note="mRNA not associated with an ORF" FT CDS join(complement(9721..9794),complement(8747..9677)) FT /db_xref="GOA:Q9UTF7" FT /db_xref="SPTREMBL:Q9UTF7" FT /label=SPAC1B2.03c FT /note="SPAC1B2.03c, len:334, SIMILARITY:Saccharomyces FT cerevisiae, SUR4_YEAST, sur4 protein, (345 aa), fasta FT scores: opt: 1036, E():0, (48.8% identity in 332 aa)" FT /gene="SPAC1B2.03c" FT /product="GNS1/SUR4 family protein" FT /protein_id="CAB61470.1" FT /translation="MDLTGAHMLKIHRPSIDHPFGVDLWHLFEQLSIKTIGWNPSEFEY FT IPGKTPMSQWSSVIVSITAYYVIILSGRAIMTNRKPLKQRRLFQLHNFILTIISGALLA FT LLVEEVFRNYMRNGLFYCVCDSRHFTQRLVTLYYLNYLTKYLELMDTVFLFLKKKPLAF FT LHCYHHGITALLCFTQLLGRTSVQWGVIGLNLYVHVIMYSYYFLAACGRRVWWKQWVTR FT VQIIQFVLDLILCYFGTYSHIAFRYFPWLPHVGDCSGSLFAAFFGCGVLSSYLFLFIGF FT YINTYIKRGAKKNQRKAAGKADNTSVAAAAGSEALAATTATNASPFSARSRKL" FT misc_feature join(complement(9721..9776),complement(8873..9677)) FT /note="Match to PF01151 GNS1_SUR4, GNS1/SUR4 family Score FT 428.24" FT misc_feature complement(9678..9692) FT /note="ctaactttggaatag, splice branch and acceptor" FT misc_feature complement(9715..9720) FT /note="gtaagc, splice donor sequence" FT CDS join(11677..11825,12237..12510) FT /db_xref="GOA:Q9UTF6" FT /db_xref="SWISS-PROT:Q9UTF6" FT /label=SPAC1B2.04 FT /note="SPAC1B2.04, len:140, SIMILARITY:Saccharomyces FT cerevisiae, COX6_YEAST, cytochrome c oxidase polypeptide vi FT precursor, (148 aa), fasta scores: opt: 385, E():6.2e-20, FT (45.8% identity in 142 aa)" FT /gene="SPAC1B2.04" FT /product="putative cytochrome c oxidase polypeptide vi FT precursor" FT /protein_id="CAB61471.1" FT /translation="MKAVQRIFQTGRFSVAAGPSVRFQAGFLAANRQVRFSSNHGVSLE FT EINTKYNDFFSNVQDQFELQRGLNNCFAYDIVPSSDVIEQALRAARRVNDFPTAVRIFE FT GIKVKLPTKEQYQAYVKELKPVCNELGIVLKEDLFK" FT misc_feature 11826..11831 FT /note="gtatgt, splice donor sequence" FT misc_feature 12225..12236 FT /note="ctaactacgtag, splice branch and acceptor" FT CDS 13251..13599 FT /db_xref="GOA:P41389" FT /db_xref="SWISS-PROT:P41389" FT /label=nda4 FT /note="SPAC1B2.05, len:116" FT /partial FT /gene="nda4" FT /gene="SPAC3F10.01" FT /gene="SPAC1B2.05" FT /product="cell division control protein nda4" FT /protein_id="CAB61472.1" FT /translation="MAAATGWERSAVYYTPVLPGEQELDSNVSHEKNFIQFIEEFVIDN FT DFIYRTQLRDNLVVKQYMLNIDLRHLISYNEDLAHLLLSQPTDILPLFESAVTTVAKRL FT LYRSQENASTNI" FT misc_feature 13463..13599 FT /note="nominal overlap with cosmid SPAC3F10 EM:Z69369 S. FT pombe chromosome 1" XX SQ Sequence 13599 BP; 4440 A; 2520 C; 2314 G; 4325 T; 0 other; ttgaaaaaaa tttagttcaa ctgtaaatca aaaacacgtt aattttacat ttaaaaatgt 60 aaaatataat gcggccagag aggttcgaac tctcgcgttt tacaacagca gggatcaagg 120 cagaagcctc ttaaatctgc ccccttagac cactcgggca tagccgctta attgtacaaa 180 ctaattaaat agaggtatat atctataaaa atagttgcgt gtactgtaaa ttgtctgggt 240 ttattagagt atatgtacac aacctgacta aaatcgtata aattagttaa aaaaaatgca 300 ttggattttt tataccttga gagccatgcc aactccaaag gtcaatattt ggtttaatga 360 tttttttttc cttccctttt ctttatttaa cacactaaat gtcgggtaac tgcgagttaa 420 taacgaacat gatcagttta attcaatttt cattcttttc tatttccata tagaattgtg 480 gctgtaaccg cgaagcattt catacggaaa gtcgccttta tttacataag caacatcttt 540 gttgtgtggc tataggagtt aaagcaaaaa aggcgaatta ctaaagcaca atgaaatggc 600 aaatctttag taataagtat attatttcgt gccgatgttc cataaacttg gttaaaataa 660 tttggaaaca tgattctagc tgtaattcaa tttttttaaa ttcataacaa tttttaattt 720 actgaatgat aaactttcct tctgttttga tttactcgtt gacttgtaaa ttgataatta 780 aaccataaaa tacctaataa ttcataataa aaaaatttaa aaaaataaat tgatgttttt 840 caaatgacct gtctttgcta aatacttcaa aacaaacaaa cagaaaaatc cacgtacgac 900 acatttattt ctggtttaaa cgcggacgtt acgatcaaat tcttaccgca tttctcccat 960 tcacggaaac gaccgaacgt cttaccggag gaagtaaatt ttgtttcaaa actaatacca 1020 tttttttaaa aaattgcaat ctgctgatac actcagtttt atcgccatca ttctcgttcc 1080 attttatgtt tacttcattc ccatcaattt ctgcctataa tcacgttgtt aaatttcctt 1140 aaaatagata acgcaaaacg attggatacg ctgcatgctt gctattcttc ttcgtgtttc 1200 tttgccagcc ttgcggccac accttttacc tccaacacaa cacttgttct tttgcatttc 1260 taccctggga cgttaggcag tagcctttaa ctgtatacat tctttcattc tcttgtttcc 1320 attgagtaca agacaaattt ctatcgcgtg aagcatctct tgggacgagg aatttcgtta 1380 taaacaagag aatttggaat atttatttgg tttttattta tagtaaggag gtaagcactt 1440 tgaacgctcg tgtagatacg tgttattttc cttggtcttc ttttaggaag gatcttgtta 1500 tctttcgatt tcctgttctt cgatctcttg tttgagttaa ttattgtttt ttctctatta 1560 tttttgcaag ggaggagtaa ttaatcagca agtaggagat taaaaattta tattattttg 1620 tttctattcg ataaaattaa tttttcttct actttttttt attttttttt tcaaatttct 1680 aacttgattg ctgaagtcct ttatacatat acaatcgcat aaggttgagg taattatcct 1740 tttcttttta cttaagacat ttgttcaata cgttgccaac catcaattta cattttttgc 1800 tttttgattt gtaaatatgg agggcatcct ggcattcgat cgcgaattag acgttgccct 1860 tttggatcgt gttgtccaaa ccttttacca aggtgtcggt gcagagcaac aacaggctca 1920 acaagtcctg acccaatttc aggcacatcc agatgcatgg tcgcaggctt actccatctt 1980 ggaaaaatca gaatatcccc aaactaaata tatcgctctt tccgtccttg acaagcttat 2040 caccactcgt tggaaaatgc ttcccaagga gcagcgattg ggaattcgca attatattgt 2100 tgctgttatg ataaagaact cgtcagacga aactgtcctg caacaacaaa aaacttttct 2160 taataaattg gacctcactc tcgttcagat tcttaaacaa gaatggcctc ataattggcc 2220 caacttcatc ccggaaattg tccaagccag taaaacaaac ctttcacttt gtgaaaataa 2280 catgatagtc cttcgtcttc tgagtgaaga aatttttgat tactcagctg agcaaatgac 2340 tcagctcaaa accaaaaatt taaaaaacca aatgtgtggc gaattcgccg agatttttca 2400 actatgctca caaattctcg aacgtgcgca aaaacctagc ctaatcaagg ctaccttggg 2460 aacacttctc cgatttttga attggatacc ccttggctat atatttgaaa caaacattgt 2520 tgagttaatt acaaatcgat tcctaaatgt tcctgatttt agaaacgtta ccattgaatg 2580 tcttaccgaa atagctagtc ttacttctca acctcagtac aacgataaat ttgttacaat 2640 gtttaacctt gtgatgacct ctgttaattc tatgcttcct ttacaaactg attttcgtga 2700 ggcttatgaa gaaagtagca caaacgagca agactttatc caaaatttgg ctctcttcct 2760 ttgcgctttc tttagctctc atcttcgacc attagaaaat cctgaaaatc aagaagtcct 2820 tcttaatgct cattcctacc ttcttaatat ctcgcgaatt aacgagcgag aaattttcaa 2880 gatctgcctg gaatattggt caaaattagt agctcagctt tatgaagaaa tgcagcaaat 2940 ccccatgtct gaaatgaatc cattacttaa tctttctagt cctacatctc tcatttcttc 3000 taatcctaat atgttagcca atcttccttt aaggaaacat atctataaag atatactttc 3060 aactcttcga ttggttatga ttgaaaacat ggtcaagccc gaagaagtcc tcatcgtcga 3120 aaatgacgaa ggtgaaattg ttcgtgaatt tgttaaagag acggatacaa ttacccttta 3180 taaatctatg cgtgaggttc ttgtgtacct cactcacttg gacgtggttg atactgaaat 3240 cgttatgact gaaaaacttg cacgtattgt tgttggtaca gaatggtctt ggcaaaattt 3300 gaatactctt tgttgggcaa tcggctcaat atccggtgct atgaatgaag aaatggaaaa 3360 gcgctttctt gttaacgtga ttaaagattt attgggcctt tgtgaaatga aacgtggcaa 3420 agataataag gctgttgttg cctctaacat tatgtacgtt gtaggtcaat atcctcgctt 3480 tttaaaagct cattggaaat ttctcaagac cgtcgtcaat aagctatttg agtttatgca 3540 cgaatatcat gaaggtgttc aggatatggc ttgtgataca ttcattaaga ttgctcaaaa 3600 atgtcgtcgc cattttgttg ctcaacaact gggagaaacg gagccgttta tcaacgaaat 3660 tattcgtaac ttggccaaga cgactgaaga tttaactcct caacagactc atacttttta 3720 tgaggcgtgc ggttatatga tttctgctca acctcaaaaa catcttcaag aacgtctcat 3780 ttttgacctt atggcgttac ccaatcaggc ctgggaaaat attgtcgctc aggctgcaca 3840 aaacgctcaa gttttagggg accctcagac cgttaaaata ttagcaaatg ttctaaagac 3900 aaacgttgct gcatgtactt ctattggttc cggtttctat cctcaaattg ctaaaaatta 3960 tgtagatatg cttggtcttt acaaggctgt tagcggttta atatcagaag tggttgctgc 4020 ccaaggaaat attgctacca aaactcccca cgtcagggga ttacgaacta tcaaaaaaga 4080 aattttgaaa ttagtagatg cttatataag tcgagcggaa gatttggagt tggtcggaaa 4140 tactctcatt cctgcgcttt tcgaagcagt gttgcttgat tatttacaaa atgttcctga 4200 cgctcgtgat gccgaagttc ttaatttgat aaccaccatt gtcaatcaac ttagcgaact 4260 ccttactgat aagattcctc ttgttcttga tgctgttttt ggatgcaccc ttgaaatgat 4320 tagtaaagat ttttcggaat accccgaaca tcgtgcagca ttttttcaac ttttacgcgc 4380 cattaacttg aattgtttcc ccgctttgct caacatcccg gcaccacaat tcaaactagt 4440 gatcaatagt attgtatggt cctttaagca tgttagtcgc gacattcaag aaaccggact 4500 taacatctta cttgaactta ttaataacat ggcgagtatg ggacctgatg tttcaaatgc 4560 atttttccaa acttattata ttagcttact acaagatata ttgtatgttt tgactgactc 4620 tgatcacaaa tctggcttta agcttcaaag cttaattttg gctcggcttt tctatctggt 4680 tgaatcaaac cagattactg tacctctcta cgatccttct caattccccc aggaaatgaa 4740 caatcaatta tttttaagac agtatatcat gaatctacta gtcacagctt tcccccatct 4800 tcaacctatc caaatccaag aatttgtaca gacagtgcta gctcttaatc aggacagcat 4860 caaatttaaa cttgctttac gtgacttttt aattcaattg aaagaattcg gcggggataa 4920 cgctgaactt tacttggagg agaaagaaca agagttggct gctcaacaaa aagcccaact 4980 ggagaaagct atgactgttc ctggtatgat caaacctgtc gatatgccta ctatggagga 5040 ggaagaacta tgatattctt cagcaaaaac gtatttaagc ttagaacttt aaaatatgaa 5100 aggaattata tatttggtat cttttactat tgacttaatt gtggatgtta tttatccctg 5160 ttacttgaga agtttactta attccttttt tttctttttt ttttttttga aaagcaagaa 5220 gggtttttga catgacatgg cccgtaattc aacgtgttag atagcaaaat gatggcgcca 5280 gttgttattg attgcaattc aaactatata aaaaagtaat aaaaaagcat aaagtcttta 5340 gagattcaac tttccgtgca gtgttgtaaa ttagaaaatt aaagcattgt aaggatttgg 5400 gttgcctcat tttttatact gtttataaat tgaacgagca gctatacttg aataacacta 5460 tgaagtctcg tgtaagagat ctcaatgcga cgttgaagtc ctttttattg aatgctggcg 5520 ttatgcaacc ttgctaaagg aaacaccaac gtattttcac ataactacgt ttttgcttct 5580 agaaaatgta ttattacctt taataaatta tgtagctact actattccgt tagagaatac 5640 ggtaagaaag aaaaacgaaa acattaaaca taaatcaaac ttacaactac aaatatgact 5700 attcgtgtag taatttggaa taaaaaaaat tccaaattac aaaacatcac ctaactaaaa 5760 cctttttgag aattccgtaa tttaccatgt gaactttcgt ctcttctgac tttgtctaat 5820 aaacagacaa tcagacccaa aacctgaata ctaaaattca acttcttcac gcaaattaga 5880 ggagatgtag ttcaatgcta aggtactcga cattccccaa atacccactc gccatccacg 5940 atacaaacct tctattccaa atttacccgg atcttcttcg cttaaaagac accatatggt 6000 accgacgata ccagtgtatt tgcctacggg aacgatagtt tggggtggaa ggttgcattc 6060 atactgggct tgtgctcttc gaagtaccat ttctaaaggg catttgagaa gaaattgaac 6120 ggctgaagtg cccaagccaa ccattgcatc aagtgtagga gatgagccca aaaagttgcg 6180 gaatgttagt ggaagcacac tcgaaacaaa tggtggtaag ctgacataac aaactgtggg 6240 taaaattaac gatgaagggc agtaaaaagg caatgctttc aagcattgtc tgatagtaag 6300 aggtttaaat tttttatgcg aattgccaga agtttcagaa gctgaagaca aataggaaga 6360 tgaggaaatg gggaaaagaa ttatttttgt tctggcaata tcaaggggag atagaataag 6420 agcagagatc gcagaagtaa tggatttgat gaaaagggaa agaagaggcc gaacagaatc 6480 tataggtgaa ataatgtttg gatctgctat tgcgagagct ccagataatg ttgccgaaag 6540 ccaggactgt aggccggaat aaagtaagtt atgcaaaaag ctgattgtat gacctttcca 6600 taaaccccta gctccttctt tctcccatag ctcactaatg atacttttaa tcgaaaatct 6660 tttcgaatga attgtatagc ttctctcgat gagattcgaa ggatcagtta catagccaga 6720 cgcatcgacg caaagtttct cagctagctg ttctgttact gccttttctg tggtaggtgt 6780 ttcaaagtaa gcatagattt cgtgttcatc atcactgaga ccttcctgtt ctgtgccatc 6840 gggaatatcc tcatcataag gctcctttgt ttgtttccca tcacgctcaa ttttagttcg 6900 ttttggtaaa tattcttcta cttgacagac agtttttgct acttccaatg gctgtacaaa 6960 aaacgtcgtt aaatatttgg tcactagaat acttctgagt gtctcaaaaa tctcactctt 7020 gcttatggtc ggttgcgtct caaacgttgg ttctggagtt atcgaaaaag taggctcaac 7080 attgttaacc acgacatatg gtctgtatgg attcatgctg tatgcttgct cttttccaaa 7140 atgagttctc caaactcgtt tacgaatgat tcaatatata gatttaactg caaataattt 7200 caaaaattgc ttagctttgg ataaaaaatt aataaaagaa gtcgttaacc ttcatcaatc 7260 ctttgaattc tggtaaatta acaaactttt tggtaccaaa gtgtgatggc ttatagtaag 7320 gtatcaccaa cttgaaggta tgatacgcac agaaagcaat ggacccaaaa gttactatac 7380 accaaattct gcaaaatatt attacgacaa tcactagaca ttattaaaaa atctactaaa 7440 ttatcttaat gaaaattggt aacaactcaa gaacaaacag ttaagtttgc tgtgcgcctg 7500 ctttgaaaat gaaaatcaat aactggacgt acaatccaat aataaatgtt ttatacttac 7560 atttcaattc aaattgtcaa acacaaaaat gcaaatctta tatctccaca atgactaaaa 7620 gcaagaattt aaaactaaaa cacttcaaaa acgaccatac aaagtcggtt caatacatgc 7680 acaaatagtt gttgaaagca catacataag tatatatatc tatatttata taatgatcat 7740 ccttcaaatg ccattcaact cattctgatc cactgaaaca acaaaccaaa gtttacgcga 7800 gcaattaata catgatagac gataataata tgtacattaa ggtaaatgcc tatcaaactc 7860 acaagtaaaa gaatatgaga aaactttgta gaaagttagg aaaaaaggaa cacgtagaaa 7920 aaggagcgtt ccatcgagct tgaaatatcc gtccaaactt tactaacttt tgttcaagta 7980 gattggggtt gttttagaaa caagaaatta ttactttgaa ctagacgcaa accacacgaa 8040 ctagacaaaa gatgttaaaa agaatggaaa tatttggcag aaaggaaaag aactcgaaac 8100 gcgacgcatc cctaattatc gaatggtaaa tagaaagaga gaacgcagaa acttgaagat 8160 gtcgaaatgt cacccaatat acacaaaaga aaagggaaat gaagaacgaa ggcacataaa 8220 gaagcaaacg actattttaa cccgctttct atttttcttt aaaaggatgt cttaaatact 8280 attaagacca tagacatacg ggtaacaaat cgatgcttgc aataactaaa ttaagataaa 8340 aagcacccca taaaccaatt gcaatttatg tctcaggaat tagagaaata ttaaacagaa 8400 gcagacatac gctgaaaccc atgcattccc accgtttcaa gcaaagaaat aaatccgcca 8460 tctaaatttt taaagaaaaa aaactgaaag taaaaaagaa agaagaaatg acgaccctag 8520 aagagccgtg cataagagta aaataaaaaa aaccaaaagc aaggaacttt tagatggctg 8580 gaaaaaatga tattttccaa tttcaatccc aaagtatcgt cttttgagtt tttttccttg 8640 tgaaaaagat gacgacggta ccatgaaatt ggactacgct taagaaagtt tgaaaataca 8700 aaagaaagct aaacaagggt ctgcacgccg tacacattcc tctccattag agtttccttg 8760 agcgagcaga aaagggagaa gcattagtag cagtggtagc ggctaaagct tcagagccag 8820 cagcggcagc aacagaggtg ttatctgcct taccggcggc tttcctttga ttttttttgg 8880 caccgcgctt gatgtaggta ttaatgtaaa aaccaatgaa gaggaataaa taggacgaaa 8940 gaacaccgca accaaagaag gcggcaaaga gagaaccaga acaatcaccg acatggggaa 9000 gccaagggaa gtaacggaaa gcaatgtggg agtaggtacc aaagtagcag aggatgagat 9060 caaggacgaa ctgaatgatt tgaacacggg taacccattg cttccaccaa actctacggc 9120 cgcaagcagc aaggaagtag taactgtaca tgataacatg aacgtacaag ttcaagccaa 9180 taacacccca ctggacggag gtgcgaccga gaagttgagt aaagcacaag agagccgtaa 9240 taccatggtg gtagcaatgg agaaaggcaa ggggtttctt cttcaaaaac aagaacaccg 9300 tatccatcaa ctccaagtac ttggtcaagt aattgaggta gtacaaggta accaatctct 9360 gcgtaaaatg acgagaatcg caaacgcagt agaagagacc gttacgcatg tagttgcgaa 9420 aaacctcttc taccaacaaa gcaagcaaag ctccactgat gatagtcaaa atgaagttgt 9480 gaagttgaaa aagacgacgt tgtttcaaag gtttgcgatt tgtcatgatc gctcgaccac 9540 tcaaaatgat aacatagtaa gcggtaatgg atacaattac gctcgaccac tgagacatgg 9600 gagttttacc cgggatgtac tcaaattcag agggattcca tcctatagtt ttgatgctca 9660 gttgctcaaa caaatgccta ttccaaagtt agttttaatg cataattacg ctttgcttac 9720 cataggtcca ctccaaatgg atggtcaatg ctgggtcggt gaattttcaa catgtgtgct 9780 ccggttagat ccattctccg ctgagaagac aaggaaatca acacatgtac acaataaata 9840 tttgagtttg aattttaaaa tattttttaa aatattctaa aaattataat ttctaaattt 9900 taaatcccat atgtgtataa tttgacataa ccagcccttc ccggcatctt gccatcctct 9960 tttttttttt tttttactag tccgttccga tggaactgaa gaaaggcagg tcacaaaaaa 10020 aaactaatca ctgcaagtaa acaaacaagt tacattctac tcaatcgtca aacaaacgta 10080 ttgacccatg gatgcccaaa gcacatccaa aatgtgaaat cttggagccc tctgaactcc 10140 taacttttac aaaaagctct tcttattctt cttatttttt cgcacgacta tgtgcgatcg 10200 tgcaaagcat ctgctgtacg atacgtgtgt gcgcaattat tttgatcgat tatagactac 10260 tagttttcac gattggtcct catcataaga tcaatggcga aaggtggatt ctcaattttc 10320 caccttccgt gaaagtatgt ctttaaaaaa ttcatttatt aacatttgca aaacaaatac 10380 ctgcaactgc ctcagttctt catactttgt tttccattcc gttttccggt tcaacaaatt 10440 tacgttacct atactggccc aaccaagtga cattgttatt tttttatttt ttttaccaat 10500 taaattgaac caattttacc acaaaaagca catgctactc agataagtaa cgcattccca 10560 aaagtaaaca aaagacggaa aagagatggg ttgggcattt acaagggtag ctgaactgat 10620 gctttagtaa aagtgtttat tgaagaatgg aaattttaaa agtcagtttt tcaagattcc 10680 cataaatttt ggtagatatt agaaaatctt actagtgagt gagattgatg gtgacataaa 10740 cattcaaaag ccaagcaatt ttagaaaaaa gaagtaatat gaaaaagaga taagttaata 10800 aaaaaaatgc atatgaatat taaaaatttc gtacgttatc cacactctta ataaaaaagg 10860 ttagattgtc caacaatttt tttgtagcag tcaattacaa gtgaaaagaa aagtattcac 10920 ttcaccaatc accgatggct tcaaaaattg attgagtagc ccttcgacat ctctcattga 10980 actttttttc ggattatgtt ttccttccat ttggtactcc tagagtatta gtggagctag 11040 aatgcttaat ccttcgaata gacctgccta tagaaagtac atctaaaact ccaacatgag 11100 tttcaattca cttgaatttg tatctctgac ataactattt aaatgaatat ctatcagcaa 11160 aatgtcttcc gctaaatata aaacagatga gaattttcat tctacagcat agtaaaagtc 11220 atatttctct aattaatgaa acagctgtct tgtataaaca ctccagttta attgagcttg 11280 cttgaaaatt ccatgtcgaa ctaatactct acataacaag taaatacttt aaaactaaga 11340 aaatcatttc atagcagtag acctttagaa gctacaataa catggaatgc ccttagtctg 11400 tgagccgtaa atcttcattt aaacacggct ctcaataatc gatctgtaca gattactcac 11460 aaccaagtgc aaaacatatt tatataaaat tacagtcatt aggttttctt catcctactt 11520 ctaatataac tgaatagctt ttttcttgaa tacatagtct atactagaaa actgtttgct 11580 tcttgatata ttacaaacct tagcgtacta ctacttccat ctactctcca ctccccttca 11640 cttttattta gcaagaagca attctaattc attataatga aagcagttca acgtattttt 11700 caaactggcc gcttttctgt cgccgcagga ccctcggttc gttttcaagc tgggttttta 11760 gctgcaaaca gacaagttcg tttttctagt aaccacgggg tttccttgga agaaataaac 11820 acaaagtatg taaaaaaacg acgataaggg aataggtaat tgttcggcat gttgcaatgc 11880 ctgaaaagta actccattca gcacttttat tatcaaatgc ggaaatagga atgctgggaa 11940 ctgcaaagaa taaaatgaac acgaaagcag tctgttttat cattgacttt tgagtaccca 12000 atactgaaag tggtttgaat attttcattt tagcatctct agaatgatag taaatgagcg 12060 ttcatagcta tttatttgtc tgctattttt tgttcttttc tcagttttca cgtttttagt 12120 ttttacacaa gaaaaattga ccatttttcc ttctttggaa gcttattctt acttctgctc 12180 tgctctgctt ttcctttatt taaaatttct tgttttactg tttactaact acgtaggtat 12240 aacgatttct tttcaaatgt tcaggatcaa tttgagctcc aaagaggcct aaataattgt 12300 tttgcctacg atatcgtgcc ttcttctgat gttattgaac aagctttacg tgctgctcgt 12360 cgtgttaacg atttccctac cgccgtaagg attttcgaag gtattaaagt gaaactacca 12420 accaaagaac agtaccaagc gtatgttaag gagcttaagc ctgtttgcaa tgaattaggt 12480 attgtattga aggaggatct ttttaagtaa gtccgattaa gtttcttgat ctgtctcctc 12540 ttcttttgaa atttgtagct ctttaccaca actctccttt tcttggtgct taactatgat 12600 ttgcgttttt caaaggactt taaaaaaact gatttactga ttttgattat catcactttt 12660 tttctgtccg cacgcaatga tgtttcttta ggattaagaa attatcaaat aaaaatgcca 12720 ataccatttc tcatacaaac agaattgcta tagtaatctt atctcttttt cttttttaag 12780 tctagtatag cagtgaatct gtaacgatat acatcttcat tttgttcacg tagaaaatag 12840 cttgcagtta atacatgttt acttaaaatg ttaaaaaaaa aattgtaagc agactatctc 12900 cttttaacaa aagatttaag ggtgtagttg aagttcgttt cagcaagggc aatatgtatt 12960 agtcctttca ccaaacacca cagaggttgt tcaataatat attttacagc attacattcg 13020 tttcttcacg cgtaaaatat ttattgcagt tacatgtaat ttaagaacat atttatatca 13080 tttttgcaac tcattctgta aaggttttga agagcttttc taatttttgt tttatttttt 13140 cgaagagcag cgaaatttgc ttcatccttt attttatacc atatcatctt ttttatctcg 13200 cttttttatt tttttttaac tcattcccct tagtcttttt catcacaata atggctgcag 13260 caacaggttg ggaacggagt gctgtatatt ataccccagt tctcccagga gagcaagaat 13320 tagattccaa tgttagtcat gagaagaatt tcatacagtt tattgaagaa tttgtgattg 13380 acaatgactt tatctatcgt actcaactaa gagacaatct cgtggtaaaa caatacatgt 13440 tgaacataga tcttaggcac ctgatcagtt ataacgaaga tctagctcat ttgcttctga 13500 gtcagccgac agatattcta cctctgtttg agtctgctgt cactacagtt gctaaacgcc 13560 tactttatag aagtcaagaa aatgcttcta cgaatatcc 13599 //