ID SPAC1B1 standard; DNA; FUN; 15471 BP. XX AC Z98532; XX SV Z98532.1 XX DT 13-AUG-1997 (Rel. 52, Created) DT 15-OCT-1999 (Rel. 61, Last updated, Version 4) XX DE S.pombe chromosome I cosmid c1B1. XX KW amiloride resistance protein; car1; importin beta-1 subunit; sod1; KW Zinc finger. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-15471 RA Oliver K., Harris D., Barrell B.G., Rajandream M.A., Wood V.; RT ; RL Submitted (13-AUG-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; O13863; O13863. DR GOA; O13864; O13864. DR GOA; P33532; P33532. DR SPTREMBL; O13862; O13862. DR SPTREMBL; O13865; O13865. DR SWISS-PROT; O13863; YDU2_SCHPO. DR SWISS-PROT; O13864; IMB1_SCHPO. DR SWISS-PROT; P33532; CAR1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S.pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1B1 is overlapped at the 5' end by cosmid c16E8 and at the CC 3' end by cosmid c17A2. XX FH Key Location/Qualifiers FH FT source 1..15471 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1B1" FT /map="IL" FT misc_feature 1..38 FT /note="nominal overlap with cosmid SPAC16E8 EM:Z98529 FT S.pombe chromosome 1" FT CDS join(1711..2872,3069..3343) FT /db_xref="SPTREMBL:O13862" FT /label=SPAC1B1.01 FT /note="SPAC1B1.01, len:478," FT /gene="SPAC1B1.01" FT /product="hypothetical zinc finger protein" FT /protein_id="CAB11080.1" FT /translation="MSEHSPEASSTYAQVTSNDELSSNKIYMNADQNNSRKKEMDGSLQ FT NNGGRLQNVNPLGGNESMSAVATSAASSLPTAENGVSLNAASPTIHSNTPTVVSHPVMS FT GSELKGEESHNSPGTLNGTSVANASKQPNMPNATFRCDKCDMMFVKQSGLTNHKRTYHQ FT VETVVIIGHRRYVWRRNENGRFQCVCGRQNWRRPVNFASHAKQCPSFLAMDPNNIPPEI FT NKVSPHDDLRPLSDSRRRARRPHPSDTIPPGASMARSDPSQVPESNPSAAAAVAAAAVA FT AAANLTNGVNPPEVPRNLNSSLVDAAESLANVSQQQHHRHPFARQPDYSAHSIPRTAAP FT YAPSMNMFAQNGPNTSLLPTAMPSDVSISSSLQQQPIHPSYDSRFSKAPQGTDALAALG FT YGTPSSAATLCPLYRDTPAAIVSEKLHLRLANLRIAYCEDCREFISLNAALDHRRSHHQ FT QNITGDLVHVYSDFLDFQNC" FT misc_feature 2125..2196 FT /note="Match to PF00096 zf-C2H2, Zinc finger, C2H2 type FT Score 30.83" FT misc_feature 2873..2878 FT /note="gtatgt, splice donor sequence" FT misc_feature 3058..3068 FT /note="ttaacctttag, splice branch and acceptor sequence" FT CDS complement(4109..5722) FT /db_xref="GOA:O13863" FT /db_xref="SWISS-PROT:O13863" FT /label=SPAC1B1.02c FT /note="SPAC1B1.02c, len:537, SIMILARITY:Schizosaccharomyces FT pombe, O14152, hypothetical 44.9 kd protein c3h5.11 in FT chromosome i., (393 aa), fasta scores: opt: 617, FT E():2.2e-31, (42.1% identity in 309 aa)" FT /gene="SPAC1B1.02c" FT /product="hypothetical protein" FT /protein_id="CAB11081.1" FT /translation="MEPGSKLSEDETFSQTFNEEEQEDSRNKDILAFDPSVDNEPLLTK FT KLSSLSIYSEPSPDEASNLQELKFVSSPPSVRVPRSRRNRRNSRVDSEARKRQFDRVKH FT SVSNSCKLHLSLQGQEAAQLRSDSLYLEASDKRDLTSLVTRVKELARKLSAARLAFRFR FT KVLLICNDNKESIERSVELAQWLLDTFSFTPSSSHNNMASSNTQSNTQLSEMESEEKSF FT NKDVYPNDEYTPFTPKNQFVIYLEDTLASLDVVESLSPKKNVRFWTSELCTQCPNLFDC FT VITVGDDSAALRASWLFQDVVPPVLSFSTAKAGFLSILPIAEYTKTLDLIFHRGFTVNL FT RMRFQCSIMRYVGEHSTHICEGQYSVLNELLIDRGPNPFMISLDLYVENEYITTLQSDG FT VCVSTPTGSTAYSVAAGGSLCHPGIPAILISAICPHSLSFRPIILPDSMTLRIVVPLDA FT RSNAWCAFDGHHRIELGLGDYISISASSFPFPSVIRSKYSKDWFDILRQTLNWNDRKGR FT QRSSRYKSHVHKTNTSEEQN" FT CDS complement(6574..9165) FT /db_xref="GOA:O13864" FT /db_xref="SWISS-PROT:O13864" FT /label=SPAC1B1.03c FT /note="SPAC1B1.03c, len:863, SIMILARITY:Saccharomyces FT cerevisiae, IMB1_YEAST, importin beta-1 subunit, (861 aa), FT fasta scores: opt: 2131, E():0, (40.8% identity in 872 aa)" FT /gene="SPAC1B1.03c" FT /product="importin beta-1 subunit" FT /protein_id="CAB11082.1" FT /translation="MNAGEFLAQTLSPDANVRLNAEKQLENAARTDFAQYMVLLAQELA FT NDNSMPYIRMAAGLALKNAITAREEARKLEYQQLWQSLPVEIKQQVKSLALQTLGSSEH FT QAGQSAAQLVAAIAAYELATNQWPDLMVTLVANVGEGQPSALKQHSLQTIGYICESVSP FT EVLSAQSNAILTAVVAGARKEEPDAAVRLAALGALYDSLEFVRENFNNEYERNYIMQVV FT CEATQSPEASIQTAAFGCLVKIMHLYYDTMPFYMEKALFALTTQGMYNTNEQVALQAVE FT FWSTVCEEEIEVNLEIQEAQDLNEVPARQNHGFARAAAADILPVLLKLLCNQDEDADED FT DWNISMAAATCLQLFAQVVGDLIVNPVLAFVEQNIQNPDWHQREAAVMAFGSVLEGPNV FT AMLTPLVNQALPVLINMMVDPVIFVKDTTAWALGQISSFVADAINPEIHLSPMVSALLQ FT GLTDNPRIVANCCWAFMNLVCHFAPVDNHQTSVMTPFYEAIIGSLLHVTDQKGNENNSR FT TSGYETLGTLITFSSDSVLPMIANVLSIILTRLETSIQMQSQILDVEDRANHDELQSNL FT CNVLTSIIRRFGPDIRTSSDQIMNLLLQTMQTAPKQSVVHEDVLLAIGAMMNSLEEQFE FT VYVPSFVPFLSSALSNEQEYQLCSVAVGLVGDLARALNAKILPYCDDFMTRLVQDLQSS FT VLDRNVKPAILSCFSDIALAIGAAFQTYLEAVMVLLQQASSVQAPPGANFSMIDYVDAL FT RLGIVEAYVGITQAVRTDNRLDLIQPYVHSMFTLLNMITADPECSESLTRAALGLLGDL FT AESFPKGELKSYFAADWVAALLNSGKTKISSQQTKDLARWATEQVKRQARA" FT misc_feature complement(6649..6672) FT /note="PS00017 ATP/GTP-binding site motif A (P-loop), FT [AG].{4}GK[ST], info count = 13.8" FT misc_feature complement(7729..7845) FT /note="Pfam match to entry PF00514 Armadillo_seg, FT Armadillo/beta-catenin-like repeats," FT misc_feature complement(7855..7974) FT /note="Pfam match to entry PF00514 Armadillo_seg, FT Armadillo/beta-catenin-like repeats," FT CDS join(complement(10399..11825),complement(10055..10334), FT complement(9897..10004)) FT /db_xref="SPTREMBL:O13865" FT /label=SPAC1B1.04c FT /note="SPAC1B1.04c, len:604, SIMILARITY:some to FT Caenorhabditis elegans., YOT7_CAEEL, hypothetical 76.2 kd FT protein zk632.7 in chromosome iii., (676 aa), fasta scores: FT opt: 303, E():1.1e-11, (25.6% identity in 480 aa)" FT /gene="SPAC1B1.04c" FT /product="hypothetical protein" FT /protein_id="CAB11083.1" FT /translation="MYATLLMLCTNHLAYSSALSSGKNGAAAQQAANSPKTVSLMTSSS FT KAANALQTHKSSLARAASAVPFSPSKATTVSLKESASLTSLSNNKSVSNLNSISGASSP FT SGSLVNLHSLTRSASFVPQPSVPNSGQLSNADMSRHILARFPPFFHNLNEQQQKTTSFF FT LADDHLKWFTYLTQEFYQFANIPKLPSHVLSYHSLIPRRMIVTVLPVLRYATSIYKVID FT GNNGLPYSFVQLRDFTLLNDRNITNVSPWTKVDSPHVIKIREAFTTHAFEQKCMLSFIY FT FENVALYTNLLLAIVFVYNYLPSCPSLYDLFFASPVFRKRTSSFYFSQPLKATKEVLWC FT FASQLISALYSIHSSGLAAKMVSLKNVLMVGKMRLAIFGLGIMDVIQEESTEPLTSLQR FT NDCRDVGLILLALATDTENVTLSTAKAHLTRLKTIVSTDASLVELIEVLIFNEELRIQT FT LLPTMLSYMVNNYESVLLMEDVYETYLAEQVENDRLLRLLLKLEFLDDRPEYVDDPDWS FT ASGVYFVIRLFRKYMFQVQTIDDASKKPTLQSTTTPPRKLLNKAHLLSCLNKLDAGTDE FT QILLEDEFTRIIMSFKEVRTISIFEKTC" FT misc_feature complement(10005..10017) FT /note="ctaacttaattag, splice branch and acceptor sequence" FT intron 10005..10054 FT /note="confirmed intron" FT misc_feature complement(10049..10054) FT /note="gtacac, splice donor sequence" FT misc_feature complement(10335..10349) FT /note="ctaactcttgaaaag, splice branch and acceptor sequence FT " FT intron 10335..10398 FT /note="confirmed intron" FT misc_feature complement(10393..10398) FT /note="gtaagt, splice donor sequence" FT misc_RNA complement(12973..13133) FT /note="5s rrna gene" FT CDS 15236..15471 FT /db_xref="GOA:P33532" FT /db_xref="SWISS-PROT:P33532" FT /label=car1 FT /note="SPAC1B1.05, len:77" FT /partial FT /gene="car1" FT /gene="sod1" FT /gene="SPAC1B1.05" FT /product="amiloride resistance protein car1" FT /gene="SPAC17A2.01" FT /protein_id="CAB11084.1" FT /translation="MASKIASLFSPSETASKDQHENVAEDLELGTASSQSDGIHETNSE FT YDEKKREESPEVIDISNLISSDHPAHPQNWHWA" FT misc_feature 15434..15471 FT /note="nominal overlap with cosmid SPAC17A2 EM:Z99292 FT S.pombe chromosome 1" XX SQ Sequence 15471 BP; 4920 A; 2903 C; 2789 G; 4859 T; 0 other; cgagtttcta acgattgtag aagagaaagg acatgatcat tggtggacat tagaaatttg 60 ttaaagagaa atataaaaaa cagcaataaa ctaaaatgat gagggatatt gagtgaaatt 120 gggtaaatgc actaattcga tggatttatt ccaaactctt caaggttaaa atgcagagga 180 aagtattaat aaggtttcca catagcttga aatgtgatga gtgaaagatg aaaatcacaa 240 caggtcgaaa ggtaggtaaa gaaaagatga ggaaaacgag tcaaaaggag aatgacaaat 300 tgattatctc agcttttaca gaggtaaaaa atgtatgtaa catatggcat tgaattcgtc 360 gttcattgga acaacttttt ttttacttgg cctgctaaat actgagggaa aaaatgacaa 420 tacttttgat taagagtatt gatttttctt ttatttgaaa aaaattccca tgaatttttt 480 gcttaatgct ttgaattatt ggcgagtgct tgatattgaa ttatcgtgtt taagcgctgg 540 acagtttcat gggcaaatac gacatatttt ttcttgttaa gtatttttct atttccttga 600 aaatctgatg tacgcaacac atacttttgt aacaaagaca acattgttgt ttgtaagaag 660 acctaaaaat ggatgtccat ttccatcgcc tcaaacttag tgtttccccc ttctcatatg 720 gttaaagata tttcaaaata atgtttattt tcttttgttg ggagtcttta ctgctttata 780 gagttttcat aggacacctt acgtagactc ttccttccat cagttgaaga cctaaattgt 840 gtttttaaat cttttcatcc agaaaaaact acaatttaaa agtctttgca cttttaaaag 900 caattggtca ggattccctc tatgacagat gtaaacaaaa agggaacttg tgcaacaatc 960 tgttgaattt ttaattatat ggtttcgcat ttcctattcc tgctgcaagt cagggcagtt 1020 cttcacataa aaagtaaaaa accactgaaa gcaaaaaaat gaatgagtat attgtgttca 1080 gctaggaata cccatttttc atcttccacc ccggatataa acaaacatct agccagccag 1140 gttcacagaa cttcaccaat ctttttcacg ttcttttttc tttcaacatt ataatgttat 1200 tttaatatta tttttctctt cccactttcc ttactacttc tttctctata gtagatatca 1260 gatcaatata ccacggtcca tcgtatcgca ataaatgctt atcgctcttt accgatcttt 1320 cttgtaaaca aagcaaagac ccaccaacgc agattgtgta tgatttcctc acaagagacc 1380 tattttttat cggaattttt atctgctcca tcattctatc gatcccaagt tagtctctct 1440 ttgcctcctc gctttctcct gctaaattta ggacttttgt tacccttgga atgtcactcc 1500 tgtcatccta atgagccaca ttaagtctcg ttaatatttt tttgctaccc ttttgctacc 1560 ttcatgctac ttaccaccaa cacctccaca ctgcatgcga aaaatttgat tttgactgag 1620 caaagcaaag tcgagtgtga ggacgtattt tccggagata tttaaagcta acgattcaaa 1680 ctgagtcgaa attttttgtt ggtaaagtct atgagtgagc actcgccaga agcctcgtca 1740 acgtacgctc aggtcacaag caatgatgag ctctccagta acaaaattta catgaacgct 1800 gaccaaaaca atagtagaaa aaaggagatg gatgggagct tgcaaaacaa tggaggccgt 1860 ttgcaaaacg tgaatccgct tggtgggaac gagagtatga gtgcagtcgc cacatcagca 1920 gcgtcgtcgc tgcctactgc ggaaaatggg gtttctttga atgcggcttc acccaccatc 1980 cattccaaca ctcccaccgt cgtatcgcat cctgttatga gcggaagtga gctcaagggc 2040 gaggaatcac ataattcacc aggtacactg aacgggacgt ctgttgctaa cgcctccaag 2100 cagcccaaca tgcctaatgc cacctttcgc tgcgacaaat gcgacatgat gtttgtcaag 2160 cagtcgggcc tcacgaatca caagcgaacg taccatcaag tagaaacggt tgtcattatt 2220 ggccatcgta ggtacgtgtg gagacgaaat gaaaacggtc gcttccaatg tgtgtgtggt 2280 cgccagaact ggcgaagacc tgtcaacttt gcctctcatg ccaagcaatg tcccagtttt 2340 cttgcaatgg acccaaataa cattcctcct gaaattaata aagtctcccc ccacgatgat 2400 ctgagaccac tctcggactc aaggcgtcgc gcacgccgtc cacatccttc agataccatt 2460 ccgccaggcg cctctatggc acgttctgac cctagtcaag tgcctgaatc caacccctct 2520 gctgccgcag ccgtcgccgc agccgccgtt gctgctgctg cgaacctaac gaacggcgtc 2580 aatcccccag aagtccctag aaacctgaac agttctcttg tcgatgccgc tgagtctctc 2640 gctaatgttt cccaacagca acatcatcgt catccttttg cccgtcaacc agattactcc 2700 gcccattcca ttccccgtac cgctgctcct tatgctccct ctatgaatat gtttgcccaa 2760 aacggcccca acacttctct tttaccaact gctatgcctt cagatgtttc catatcttct 2820 tctctccaac aacaacccat ccatccatcc tatgactcta ggttttccaa aggtatgttt 2880 tttattatta attcgctcca tcttgtatag tttgatagat ctttgttgga tataaacaaa 2940 aaaagacttg gtcttgttaa agttgctttg cttccaatta ttcgttttac ggttgaattg 3000 gtgtatcctt cactcatcta tcagtttgtt catacgtaat tcttcttttt tcatcagtta 3060 acctttagct cctcaaggta cagatgccct tgctgcattg ggttatggta cgccttcatc 3120 tgctgccaca ttatgtccat tgtatcgaga tactccagct gccattgtca gtgaaaagct 3180 acatttacgt ttagcaaatc ttcgcatcgc ttactgtgaa gactgtcgtg aatttatatc 3240 tctgaatgct gctctggatc atcgtcgttc acaccatcaa caaaatatca cgggtgacct 3300 tgtgcacgta tacagcgatt tcttagactt ccagaattgt tagaaaatgt tgcatcttct 3360 tatatttgat cagttttata tggattttac caacttgctt tttggtttta attttgtttc 3420 ttcatttttt cgttatatta aggttttccc taatcaccat gttctcttta caatttttgt 3480 aaagtatcgg aattacattc gtcaaaccag cgtttatgat aaaagatcat cctattctaa 3540 ttttgctatc gatagccctt gtgcccagaa aaataaagaa ctcgctttaa cgattcagcc 3600 atcaataaat ggtataaact cccttggtta tagcttggat aaaatggttt aattgttgtt 3660 tatagttaac atgaacttaa attttctttt cttttatttg ttgtattcaa ttcgccgtca 3720 aaccactaag tatagctagt attcacatta acaaatagta ctttactaat aaattgaaaa 3780 gcgcgctttt actcttattg caatgtatct tccgcatatt taagaagcat cggcttcaaa 3840 tttggtactc agatatatat atttaaaaaa aaaataatta ttattattat tataatagat 3900 taacggtaat tgagctattc tattcatgac atgaaaaaat agaaagtgtt aaaagcttaa 3960 gtgttataat ccttaaaaga taactattcg tcaacaaaaa attggatgta tagacaaaaa 4020 taaaatgctg tcgtaaactt aggcttgtat agttaagaat ggtttgtatg cacgtctcag 4080 ccctgaaaat ttgacattat tataaaaatt aattttgctc ttcggaagta ttggttttat 4140 gtacatgcga tttataacgc gatgatcttt gcctaccttt tcggtcattc caattcaacg 4200 tctgtcttaa aatgtcaaac caatctttgg aatatttgct acgaataacg gaagggaagg 4260 gaaatgaaga agcggatatg gaaatgtaat ccccaaggcc aagttcaata cgatggtgtc 4320 catcaaaagc acaccaagca ttacttctcg catctaaagg cacaacaatt cttaaagtca 4380 tgctatcagg caatattatg gggcgaaaag agagactatg tggacatata gcactaatta 4440 aaatagcagg tattcccgga tgacaaagcg atcctccagc ggccaccgag tatgcagtag 4500 agcccgtagg tgttgacaca catacaccgt ctgattgaag tgtggtgatg tattcattct 4560 caacatataa atctaaggat atcataaaag gatttggccc tctatcaatg agtaattcgt 4620 ttagcaccga atattgccct tcgcaaatgt gggtcgaatg ctctcccacg tatcgcatga 4680 tagaacattg aaagcgcatt cgaaggttaa ccgtaaaccc ccggtggaaa attaaatcga 4740 gagttttcgt atattccgca attggtaaaa tactaagaaa tccagcttta gccgtactaa 4800 aagataaaac tggcggaaca acatcttgaa atagccaact tgctcgtaga gcagcactgt 4860 cgtcgccaac cgtaataaca cagtcaaaca aatttggaca ctgcgtgcaa agttcggaag 4920 tccaaaaacg aacatttttc ttgggagata aagattctac aacatccaat gacgctagtg 4980 tatcttccaa ataaatgaca aattggtttt tgggagtaaa aggtgtatac tcatcattag 5040 gatatacgtc tttattaaat gatttttcct ctgattccat ctcagatagc tgggtattac 5100 tttgggtatt tgatgatgcc atattattat gagatgagga gggagtaaaa gaaaaggtat 5160 ccagtaacca ctgggccagt tctacagagc gctctataga ttccttatta tcattgcaaa 5220 tgagcaatac ttttcggaat cggaaagcta atcgagcagc gctcagttta cgagccaatt 5280 ctttaactct ggtaaccaaa ctggtaaggt cacgtttatc cgaagcttca agatacagac 5340 tgtcagaacg taattgtgca gcttcttgac cttgaagtga caaatgtaat ttacaactgt 5400 tggacaccga atgtttaact cgatcaaact ggcgtttgcg ggcttcgcta tcgactcgtg 5460 agttgcgacg atttctgcga cttcttggca cccttacgct cggaggactt gaaacaaact 5520 tgagctcctg caggttcgaa gcttcgtctg gtgagggctc tgaatatata gacaggctag 5580 acagcttttt ggtcaataat ggctcattgt caacagaagg atcaaaagct aatatatctt 5640 tatttctcga gtcctcctgt tcttcctcat taaatgtttg agagaaagtt tcatcctctg 5700 acagtttcga gcccggttcc ataaatgact tttatgaatt ggcgaaatat gttttgggca 5760 aaataatatc aagaatgaaa cagataaatc ttctgataca ctgttcttta tttataaaat 5820 atttcaaaaa ttactttaaa agtcttagat ttccttatta atacacaggt aaactcttga 5880 ctcagtaatt catgagaagg tcgtaaagta aaatgctaat ttccctttca accaaatatc 5940 gcacactttc aatctcaatt tatcgttaaa ttccgatttt aatttaggat ttcacacttt 6000 atatctgttg catggttgtg tgcagtgatt aaataattaa acaccctaaa tacatattca 6060 aggtattact ttaattaaaa gctattttta ttaaaccaga aatttatgcg taaattggag 6120 tacaattata tcaatgaatg gatcattaca tattgtaagt tgatttatca cataaactaa 6180 ttttacttac taatcttact aatcttaatg tcctaatggt gaaatatgtt caaatatttt 6240 tttcttttaa aaaattacct atcacttcaa ctggactatt tatataaaca gttatatcgg 6300 cttgtacaat ttaatgtcga ggcacgttga cgtgaaaacc aatataagta gaatattggt 6360 ctgcaaatat actataattt aagaatattc gaaatttcgt atattaacta gattacttca 6420 tctttttcat attgctacat caattaaacc aaactaatct atgcaaatcc aattggatat 6480 tataaaaata aaagattttg atcgaattag cataaatatc taatttttcc ccttctatta 6540 aacctacact tcacgagtat attttaacac aaattaagct ctagcttgac gcttaacctg 6600 ctccgtagcc caacgagcca aatccttagt ttgctgcgaa gatattttcg tttttccaga 6660 attgagaaga gcagctaccc aatctgccgc aaaatatgat ttaagttcgc ctttcgggaa 6720 agattctgct aaatcaccta gcagacccaa ggcagcccga gtgagacttt cggagcattc 6780 gggatcagca gtgatcatat ttaatagtgt aaacatactg tgcacataag gttgtataag 6840 gtccaaacgg ttgtcagttc gtacagcctg agtaataccc acatatgctt cgacaattcc 6900 taatcgtaaa gcatccacat aatcaatcat gctgaaatta gcacctggag gagcctggac 6960 agacgatgct tgttgcaaca acaccataac agcctctaga tacgtttgaa aagcagcacc 7020 aatggctaaa gcaatatcac tgaagcaaga taaaatcgct ggctttacat tacgatctag 7080 cactgagctt tgtaaatcct ggacgagtct agtcataaaa tcatcacagt aaggtaatat 7140 ttttgcattt aatgcacgcg ctaagtctcc tactagccca acagccactg aacaaagttg 7200 atattcttgt tcattactta aggccgaaga caaaaatggt acaaaactgg gtacgtaaac 7260 ttcaaactgc tcttccaacg agttcatcat agctccaatc gccaaaagaa catcctcatg 7320 aacaacggat tgtttcggag cggtttgcat ggtttgtaac aacaaattca taatctggtc 7380 agaagaagtt cgaatatcgg ggccaaagcg acgaattatg cttgtgagaa cgttgcagag 7440 gttagattga agttcgtcat gattggcacg gtcctcaaca tctaatatct gactttgcat 7500 ttgaattgat gtttctaaac gagtgaggat aatcgaaaga acgttagcta tcataggtaa 7560 gactgagtcg gaactgaatg taattaatgt accgagagtc tcatagccgg aagtgcgcga 7620 attattttca tttccttttt gatcagttac atgtagcaag cttcctatga tagcttcgta 7680 gaaaggagtc atgactgatg tttgatgatt gtcaactggt gcaaagtgac atactaaatt 7740 catgaacgcc caacaacaat tggcaacaat acgaggatta tcagtcaaac cctgcagcaa 7800 agctgacacc ataggagaaa gatgaatttc aggattaata gcatcagcaa caaaacttga 7860 aatttgaccc agagcccagg cagtggtatc cttaacaaat ataactggat ccaccatcat 7920 attaattaag actggtagag cttgattcac aagaggagta agcattgcta cgtttggtcc 7980 ttcaagaaca gatccaaaag ccatgacagc tgcttctcgt tggtgccaat caggattttg 8040 aatattttgt tcaacaaatg caagaacagg attaacaatt aaatcaccaa caacctgagc 8100 aaaaagttgt aagcaagtag cagcagccat cgaaatattc caatcatctt catctgcatc 8160 ttcatcctga ttacaaagca atttcaataa aacaggaaga atatcagctg ctgctgctcg 8220 agcaaatcca tgattctgtc ttgctggaac ttcattgagg tcctgagctt cttgaatttc 8280 caaattcact tcaatttctt cttcgcaaac cgtgctccaa aactcaactg cttgaagtgc 8340 gacctgttcg ttggtattgt acattccttg tgtagttaaa gcgaaaagtg ctttttccat 8400 ataaaaaggc atggtatcat aatagagatg catgattttt actaagcaac caaaagcagc 8460 tgtttgaatt gaggcttcag gactttgggt ggcctcacaa acaacctgca taatgtaatt 8520 tctttcatat tcgttattaa agttctcccg aacaaattct agtgaatcat atagggcacc 8580 caaagcagct aaacgtacag cggcatccgg ttcttcttta cgggcaccag caacgactgc 8640 agtaaggata gcgttcgatt gagcagagag gacttccgga gaaacagatt cacaaatata 8700 accaattgtt tgtaaggaat gttgttttaa agctgacggt tgaccttcac caacatttgc 8760 aaccagcgta accatcaagt cgggccattg gttagtcgct aattcataag ctgcaatagc 8820 agcaacaagt tgagctgcag attggccggc ctgatgctct gatgagccga gagtttgtaa 8880 agctaagctt ttcacttgtt gcttaatttc tacaggcaag gattgccata attgctggta 8940 ttccaactta cgagcctctt cacgggctgt aattgcattt ttcaaagcca aaccagcagc 9000 catacgaata tatggcatag aattatcatt tgcaagctct tgagcaagca aaaccatata 9060 ttgagcgaaa tccgtacgtg ctgcattctc caattgtttc tctgcattta aacgcacgtt 9120 cgcatcaggc gaaagggtct gagctaaaaa ctcacctgcg ttcatctttg ctactccttc 9180 ctatcaccag agttgttatc agttaaagta atcgattttc actaaacgta gcctcaagtt 9240 cgtacttagc tcaaggcaac aaaagggcct tgttcttttt cgtactttct aaataatatc 9300 tccactgatc aagacctctt tctgtttttc aataatagag gtttacagaa aactcagtat 9360 ggtggatggt agagactagg tgtttacttt tccgtaacgc tactacttag tgcagcgctt 9420 ttcacttaca ctattacttc acaaaaattg ctacttaata gtctttaaaa tagaagtttg 9480 attgtattcc tattttttag tatattggaa gctcttgaaa attgataatt tagcatggag 9540 caatacattg ttgtcgtcta gtcaaacaag cttcactgcg taaaatttct ttcatattct 9600 taaggtataa aactgatttt gttcaaaaag gtataaggat tgactatagg gaatgcttcc 9660 tgaactcttt agtttttatt aaaattttga aattggatcg tttaaatata tatatgagcg 9720 ttaaacttcg acttgtacat gctacaaaag actacgtata tacatagttc gcctcaaatc 9780 gtcagaaaat cccgatttta aaaattattt ttatttttta acactaagat tatttgaaca 9840 tcgccgttct aactccatga acgcagtatt aattgtggtt ttcacctaga tagtttttag 9900 caagtttttt caaaaatgct tattgttctt acctccttaa aactcatgat gattcgagta 9960 aattcgtctt ctagtaaaat ttgttcatcg gtgccagcgt ccagctaatt aagttagttt 10020 attatgttca tatataaatt aaatccttgt gtaccttgtt caagcaagaa agtaagtgtg 10080 ctttgtttaa gagcttccga ggaggagtgg tggtggattg taaagtaggt tttttgctgg 10140 catcatcaat tgtttgtact tggaacatgt atttacggaa taaacgaatt acaaaatata 10200 caccagatgc ggaccagtcc ggatcatcaa catattcagg ccgatcatca agaaattcta 10260 gttttaacaa taatcgtaat aatctgtcat tctcaacttg ctctgctaga tatgtttcat 10320 agacgtcctc catacttttc aagagttagt tgcatgtttc atgtatcaaa aaagtaaaac 10380 taggcaggct aaacttacag caaaacagat tcgtagttat tcaccatgta tgataacatt 10440 gtaggtagta gcgtttggat tctcagttct tcattaaaaa ttaatacctc tataagttca 10500 actagtgatg catccgttga aactatggtt ttcagccgcg tcaaatgggc tttagcagta 10560 gaaagtgtaa cattctctgt atccgtggct aatgcgagta atatcaatcc aacgtcacga 10620 caatcgtttc tttgaagaga cgtcaaaggc tcggtagatt cttcttgtat tacatccatt 10680 atccctaaac caaaaattgc tagcctcatt tttccaacca ttaaaacatt ctttagagac 10740 accattttag ctgccaaacc agaagagtgg atagagtaca gagcactaat tagttggctt 10800 gcaaagcacc aaaggacttc cttggtagct ttcagtggct gggaaaaata gaaagaggaa 10860 gttctctttc ggaaaacggg tgatgcaaaa aacaagtcgt atagggaagg acaagatggt 10920 aggtaattat aaacaaagac aatggctaaa agcagattag tatataatgc aacattttcg 10980 aaataaataa aacttaacat acatttttgc tcaaatgcat gggtagtaaa ggcttcacgt 11040 attttgatga catgtggaga atctaccttt gtccaaggcg acacattggt aatattacga 11100 tcattcaaca atgtgaaatc acgtaactgt acaaatgagt aaggaagtcc gttattacca 11160 tcaataactt tgtaaattga agtcgcatat ctcaatacag ggagaacggt tacaatcatc 11220 cttctgggaa taagcgaatg gtatgataac acatgggagg gaagttttgg aatattagca 11280 aactgataaa actcttgggt aagataagta aaccatttca agtgatcatc ggctaaaaag 11340 aaactagtag tcttttgttg ctgctcattt aaattgtgaa aaaagggtgg aaatctagcc 11400 agtatatgcc tagacatatc agcattcgat agctgaccag aatttggtac agaaggttga 11460 ggaacaaagc tggcagaacg tgtcaacgaa tgaagattta cgaggcttcc agaaggtgaa 11520 ctggcaccgg aaattgaatt taagttactc acagatttat tgttcgagag actggttagg 11580 gatgcactct ctttcaacga tactgttgtg gccttggagg gagaaaaggg aactgctgaa 11640 gcagctcgtg ccaacgaaga tttgtgcgtt tgaagggcgt ttgcagcttt agaactagag 11700 gtcattaaag ataccgtttt aggagaattg gctgcctgtt gggccgcagc accatttttt 11760 ccagaggaaa gagctgaaga gtaggctaaa tgattagtac ataacatcaa caaggtcgca 11820 tacattttgg cctagtgagg ggtacggact ctttattgga agcacttgaa attgaggttt 11880 tcgacaactt taagggagtg aaagatggcg aatttatact gagcttggtg gaaaagccag 11940 agttttgtgg atctattgca gtagcagaag gtggttttga agatgccggt gcattatcct 12000 aaaaaaagag aattggtcag tcatttaatg ttttaaaaga aaataataag aaagaataaa 12060 agcaataatt ataaagcgaa aagaaaacaa aggtgaacct atcaaaaaca tataaaaaaa 12120 ctcaacttca catacttgat ttttatgttg aaaaaaacac cccttatcta tgtatggaca 12180 tcttccataa agttgttcat ttctacaggg aatgttggtt gagaatatgg atgatcctga 12240 ttgaacatgt aagcttatgt ttgaaataag agcaaaaaac tcgccaataa aattaattat 12300 actaaacgtt tctctttgga aatttctttt attaaaaaat aatcacttac gcctttcatc 12360 catttttcca acattatttt ataatagcgg ttgttgtatg tgggtgtacg ttgggcgctc 12420 tatgccagct ctagtaccct acgaatagat gatggtaata gaacagtagt ttggttgcat 12480 gcttcaagca tttggtttta taaaataatt tactttgata aaaagaatta gttaggagtt 12540 aagaccgtta ggtgtttagg tgcgtttcct ttacgaattg catataatag taaagtagct 12600 atcttgggaa tgtcaaacga gttgttgcta agatgatttt taacaaggta aactacagta 12660 ttaacccatt gcttgtacct tgatcgataa gtctgctgcc agctataagt ggtctaaaca 12720 ttagctaggt gcatattgcc gacaatcgct atgaataaaa atgcattgtt aattcaattt 12780 atcaagggga aagcattgca attgatcgaa acgaacggtt aagcaaagtt aacatcaagt 12840 tagatagttg atgtttttga tggtttatag acagtttgtc ttcacgaaca aatcacttcg 12900 ttcaattgca atcaaggaaa taaattggcg tgaatgaaaa aaaaaaacat gaaaataatt 12960 catattggtt tcaaaaaaag atgagcctac agcaccccgg attcccatgt tgtctccaac 13020 catagtacca acgaggccct cagacgctta actgcagtga tcggacggga actggtgttt 13080 tcgcctacgt atggccgtag acattgagtt tagtaattaa taatatatat agtattcttg 13140 gataatgttg gtaaagagaa aattgcttaa tttgtaaact gcgagtagcc aaaacaataa 13200 tatttgccaa taacaaagca agttttacag tattcatttc ccaacccaag gagttttgaa 13260 tggggaatat tcaacaaaaa gagtttcgac ttaatacttc ctgttactct tgtgaatcct 13320 caattttgaa gtcagctttg tcaagacaca tacagttcat gtttatattt taatcatact 13380 attatttgtc aggatttctc aattatattc tttgtttact tgaaattgat ctccagggaa 13440 atcttgtttt ttaaaaatct ggctgctgtg aagtaatcta ctagttagtt tttcatttta 13500 ttttagcttg taattttatt gagtgatggc attttcaatt gtagtaaata attagggaat 13560 cacttgcagc aatcaagaat tgcaattgaa cgattaacga gaacgataca gttaggtttt 13620 tttttttttt tttttttttt tttttttttt gaaaataaac attgacctta aggtatgttc 13680 ttttcaaaat taatttttat ctgatgaaca aacctgggtc tcagctacat ttgttatcta 13740 cttataccat tttgctgaat gaattcattt tttattcatt gcaaagtttt ggtatgttga 13800 agatgttgaa aaaataaata aataaataac acataactgt aagattagat agacaaaaga 13860 aatttctaga tttaatttta tcctatttta tattttttgt tgcaaaagat ttcatacgtg 13920 aacttgtcaa aatagataca aaagaaacaa gaaaaataaa gagtagaaaa aaaaaaaaag 13980 aaaaaaaaaa aaagaattaa aaagaaaaga aaattcatat tatctggttg cttcaatcca 14040 tatttctaac ttttcctcat taggatctat ctcattataa caatacttaa agccactaca 14100 aagatatgct acgtaaatca aaacacaccg tatttgcact attacattgc taaactagtc 14160 cacgataaaa aaatagtgaa gcgtaaccta attcactaac gtactaacac catctgataa 14220 aatggttcat taaacaatct cgggaaactg cgtgcgtctg tgcgcgctag catctaaaca 14280 ttacagcgtg ccgaatacca acatcaacaa cattgtaaaa atacaaacaa ataatagacg 14340 attgaattgt tattgatgta acatcgttta taaaacttgt gcctttttag aatacttatc 14400 atcttactga ataagaagaa aatacttaac aatctttatt tctgggtatt tgccaacttg 14460 gtagggcgat caaacttcaa attgtacccg atgaactgat aatttaaagg aaggtcccga 14520 atcaaatgaa actccttttg ttgacatttt ggttaaaacg gttcagcgtt ccatgattat 14580 tttctttttt tagtagtaag taggttcatc ggggattaaa tggatccatc agactcaaac 14640 ctcttttcct agcaattttc agtttaacaa ttaaaaccaa aattaagagg atacaagaga 14700 tgcttagttg ggacactttt ttgttaagag gttctctcac tttatctgcc aaaaatttgc 14760 aatctcaagc acccattact acatttccct taatgttcaa tagcatgcat ttttaatctt 14820 ctaaacttat cgatagaatt cttctaaaaa tgaattcctt tctttcgatg atcatactaa 14880 aaatttcaca attcttaaca ctttcgctac agactaccga cggtattcgc ttgccgaacg 14940 atgcttttca aactctgatg tttctcatta attgcgtttg tctgtaagaa tagcgctttc 15000 aaatatgata ttgccagtta gtgaacaacc ggaatcttgt tccggcggta atgtgcgtga 15060 agaacaaaat gtttgaatac atatattgaa cgcagggacc aatggaattt tcattatcaa 15120 ccttaacaag ctatttttcc tttattttta gttgattttt ctatacccct tgagcttagc 15180 ttcataaggg taaataagga ataaagtact agttttcttg tgaggcaaaa caatcatggc 15240 cagtaaaatt gcgagtttat tttctccgtc tgaaacggcc tctaaggatc aacatgaaaa 15300 tgttgcagag gatttggagt taggcactgc ctcctctcaa tcagatggaa ttcatgaaac 15360 caattctgaa tatgatgaaa aaaagagaga ggaatcgccc gaggttatcg acatatcaaa 15420 tttaatttct tctgatcacc cggctcaccc tcaaaactgg cattgggcca a 15471 //