ID SPAC18G6 standard; DNA; FUN; 37621 BP. XX AC Z68198; XX SV Z68198.1 XX DT 12-DEC-1995 (Rel. 46, Created) DT 04-APR-2000 (Rel. 63, Last updated, Version 5) XX DE S.pombe chromosome I cosmid c18G6. XX KW 40S ribosomal protein; chromosome segregation; GCN1 homologue; KW heterochromatin protein; Homol D box; mal3; mating factor; mra1; KW protein transport; rab subfamily; KW rna polymerase i specific transcription initiation factor; rps7; KW serine hydroxymethyltransferase; shm2; translational activator; tRNA-Val; KW vesicular traffic; YPT1-related protein 3; ypt3. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-37621 RA Connor R., Churcher C.M., Barrell B.G., Rajandream M.A., Walsh S.V., RA Wood V.; RT ; RL Submitted (07-DEC-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; O94540; O94540. DR GOA; P17610; P17610. DR GOA; Q10101; Q10101. DR GOA; Q10103; Q10103. DR GOA; Q10104; Q10104. DR GOA; Q10105; Q10105. DR GOA; Q10107; Q10107. DR GOA; Q10109; Q10109. DR GOA; Q10113; Q10113. DR SPTREMBL; O94540; O94540. DR SWISS-PROT; P17610; YPT3_SCHPO. DR SWISS-PROT; Q10101; RS7_SCHPO. DR SWISS-PROT; Q10102; YAQ1_SCHPO. DR SWISS-PROT; Q10103; CHP1_SCHPO. DR SWISS-PROT; Q10104; GLYC_SCHPO. DR SWISS-PROT; Q10105; YAQ5_SCHPO. DR SWISS-PROT; Q10106; YAQ6_SCHPO. DR SWISS-PROT; Q10107; MRA1_SCHPO. DR SWISS-PROT; Q10108; YAQ9_SCHPO. DR SWISS-PROT; Q10109; YAQA_SCHPO. DR SWISS-PROT; Q10110; YAQB_SCHPO. DR SWISS-PROT; Q10111; YAQC_SCHPO. DR SWISS-PROT; Q10112; YAQD_SCHPO. DR SWISS-PROT; Q10113; MAL3_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c18G6 overlapped by c1327 at the 5' end and c13D6 at CC the 3' end. XX FH Key Location/Qualifiers FH FT source 1..37621 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c18G6" FT /map="IL" FT misc_feature 1..98 FT /note="nominal overlap with cosmid SPAC1327, EM:AL035254 S. FT pombe chromosome 1" FT CDS complement(1..193) FT /db_xref="GOA:O94540" FT /db_xref="SPTREMBL:O94540" FT /label=SPAC18G6.16c FT /note="SPAC18G6.16c, len:64 aa" FT /partial FT /gene="SPAC1327.01c" FT /gene="SPAC18G6.16c" FT /product="putative trancription factor" FT /gene="SPAC1783.09c" FT /protein_id="CAB59875.1" FT /translation="MMQQRSGSLSLLSNAVQAGQSSDPMQDDPAKTEPGTPKGYDGSKN FT SSPASVPSWIHEKTKAGKD" FT CDS complement(1994..2773) FT /db_xref="SWISS-PROT:Q10102" FT /label=SPAC18G6.01c FT /note="SPAC18G6.01c, len:259aa; similarity: to hypothetical FT protein SW:YHZ8_YEAST P38884 (27.1% identity in 192 aa ov FT erlap)" FT /gene="SPAC18G6.01c" FT /product="hypothetical protein" FT /protein_id="CAA92381.1" FT /translation="MFGTRFFAYQFCKNWLSKRPGLVFWSSVATINAMYQTRPLYCESV FT TKTIQQTYEGLVQKRINNEDELFLLGSGPRYVSFLSIHVYDIELYIQKKDVQTVHTILQ FT KEVDPKLGLEMSMKDEEIGSRIVAALLKNEMKYAIKIVPTRNTNFSHLRGGFVRGLQSR FT MSQNDPAEQAAVSKFRSTFPVNRTCFKETALWMKLYGNDFCYIYKDSEIGHMHDENYMV FT SNLFLKGYLVGPRVNSEQARESVCLTLRRIMDGTLLF" FT CDS complement(3075..5957) FT /db_xref="GOA:Q10103" FT /db_xref="SWISS-PROT:Q10103" FT /label=chp1 FT /note="SPAC18G6.02c, len:960aa; similarity: at N-terminus t FT o SW:HP1_DROVI P29227 heterchromatin protein 1 (HP1) (46.4 FT % identity in 56 aa overlap)" FT /gene="SPAC18G6.02c" FT /gene="chp1" FT /product="chromo domain protein; required for centromeric FT silencing and chromosome segregation" FT /protein_id="CAA92382.1" FT /translation="MVSVKPLPDIDSNEGETDADVYEVEDILADRVNKNGINEYYIKWA FT GYDWYDNTWEPEQNLFGAEKVLKKWKKRKKLIAKGLLEPFDAEDNEAKKMKREKEILRQ FT QRQKRKSELTQLSQKVKEKFKKMRKKPARRIVTIANDEEEEDDQTMDEDAFERKSMQGE FT LKERNLTDKTSTLSTSFGETSPDVNPFYLSEWPTVTDSILLSKSLSSDAIPLKNGEIKS FT TMLMPSDSDNSVPGIQNSNNLENTGAFVENANSPQSNTPLSTFRHSSPLSLSPVITSDN FT DVANSLFFSNSTPLPSSLKIKKEAPKLETHTILVSDNSGSLTKQDILSYFAFIKGNIEV FT FFLKSPKKDKVCNMAYIQFDSIEQAKLAYDKGHPSWHVTLVKGKISTDMEECKVSKSIL FT KTTPSKKANARSVSFTQTTTDTLSESEKFASNVDLDENFDFNVNVTNEDAKQLKKSVIG FT SSWTTVNNDWNSVSKSDQTFENDGASKVVPAGNITLNSDNSLHHSISESEDLSSASTLS FT DYFRFVLRVGKSLYYAGELSFDISKLKAETEHQQLLRSLVSCKQVDVLRFVTSQYLEVF FT GTCLTKVLSGSLCIRSDVDMTHFKNILNRGNGAGIVLGSNYTLLLFTEDNNALMNLYDC FT QGQSNSPFWMVIFEPLESILVEWSAKNLRPKKPYHKSQSYLSYLLQLGHIDLHKIGAFQ FT ATQILIVSKQPSPEAEELEDTFREAAIPTFRGLEIPESLFLSQNVFVFLNVSLEDDFDQ FT LQFLTLAKRKSCKFFLFGLSLPLKSPNDSHVGTDFKKNNEPLDKLTYSQYLRPMFPKGG FT VVSVTLSALIKTPRLLELISPFLEIKKDSWILILPPSIVDMVKSYFVTNNPDKSLLEIQ FT NLLNTLQRYLTNPALKNVTLYQDWDIVIDDSADVSLASTLQLYQKKNYDKYRRFVLIHE FT LKNELTPVNGLDIVDYDEFKETFMRAIGLK" FT misc_feature complement(5778..5903) FT /note="Pfam match to entry PF00385 chromo, 'chromo' (CHRrom FT atin Organization MOdifier) domain, score 46.20, E-value 4. FT 6e-12" FT tRNA complement(6831..6912) FT /note="tRNA Val anticodon AAC, Cove score 63.53" FT intron complement(6867..6874) FT /note="intron tRNA Val anticodon AAC" FT misc_feature 7834..7889 FT /note="intron in 5' utr of transcript for ypt3" FT CDS join(7913..8339,8584..8664,8719..8855) FT /db_xref="GOA:P17610" FT /db_xref="SWISS-PROT:P17610" FT /label=ypt3 FT /note="SPAC18G6.03, len:214aa" FT /gene="ypt3" FT /gene="SPAC18G6.03" FT /function="protein transport. probably involved in vesicul FT ar traffic (by similarity)" FT /product="YPT1-related rab subfamily protein" FT /protein_id="CAA92383.1" FT /translation="MCQEDEYDYLFKTVLIGDSGVGKSNLLMRFTRNEFNIESKSTIGV FT EFATRNIVLDNKKIKAQIWDTAGQERYRAITSAYYRGAVGALIVYDITKQSSFDNVGRW FT LKELREHADSNIVIMLVGNKTDLLHLRAVSTEEAQAFAAENNLSFIETSAMDASNVEEA FT FQTVLTEIFRIVSNRSLEAGDDGVHPTAGQTLNIAPTMNDLNKKKSSSQCC" FT misc_feature join(7952..8339,8584..8664,8719..8852) FT /note="Match to PF00071 ras, Ras family Score 320.83" FT misc_feature 7961..7984 FT /note="PS00017 ATP/GTP-binding site motif A" FT misc_feature 8340..8345 FT /note="splice donor sequence, gtaagt" FT misc_feature 8569..8583 FT /note="splice branch and acceptor sequence, ctaatgtttttacag FT " FT misc_feature 8665..8670 FT /note="splice donor sequence, gtatgt" FT intron 8665..8718 FT /note="confirmed by EST" FT misc_feature 8703..8718 FT /note="splice branch and acceptor sequence, tactaatctagcgta FT g" FT CDS complement(9285..10703) FT /db_xref="GOA:Q10104" FT /db_xref="SWISS-PROT:Q10104" FT /label=shm2 FT /note="SPAC18G6.04c, len:472aa; anomoly:possibly spliced at FT 5' end (9288..10667,10814..10897)" FT /gene="shm2" FT /gene="SPAC18G6.04c" FT /product="serine hydroxymethyltransferase" FT /protein_id="CAA92384.1" FT /translation="MKCSNKVLTIIKLLKAPLAECDPTVYKILESEKSRQKESIALIAS FT ENFTSRAVMDALGSIMQNKYSEGYPGARYYGGNEFIDQAERLCQTRALEAFHLDGEKWG FT VNVQPHSGSPANLQAYQAVMKPHDRLMGLDLPHGGHLSHGFSTPQKAISAVSTYFSTMP FT YNVNKETGIIDYDSLEKAAIQFRPKVIVAGASAYARLVDYKRMRKITEMCNAYLLCDMA FT HISGLVAAGVIPSPFEYADIVTTTTHKSLRGPRGAMIFYRKGTRSHDKRGNPILYELED FT KINFSVFPGHQGGPHNHTITALAVALGQAKTPEFYQYQKDVLSNAKAMANAFITRGYKL FT VSGGTDTHLVLVDLTDKGVDGARVERILELVNISANKNTVPGDKSALIPRGLRLGTPAC FT TTRGFDEKDFERVVELIDEVVSLTKKINEAALKEGKSKFRDFKAYVGDGSKFSEIAKLK FT KEVITWAGKFDFPV" FT misc_feature complement(9396..9419) FT /note="PS00017 ATP/GTP-binding site motif A" FT misc_feature complement(9456..10652) FT /note="Pfam match to entry PF00464 SHMT, Serine hydroxymeth FT yltransferase" FT misc_feature complement(9933..9974) FT /note="PS00096 Serine hydroxymethyltransferase pyridoxal-ph FT osphate attachment site" FT CDS join(complement(19291..19438),complement(11353..19217)) FT /db_xref="GOA:Q10105" FT /db_xref="SWISS-PROT:Q10105" FT /label=SPAC18G6.05c FT /note="SPAC18G6.05c, len:2670aa; similarity: SW:GCN1_YEAST FT P33892 translational activator GCN1 (38.8% identity in 187 FT 5 aa overlap)" FT /gene="SPAC18G6.05c" FT /product="GCN1 homologue" FT /function="putative translational activator" FT /protein_id="CAA92385.1" FT /translation="MSVEEPGIEAHGHKDRMLYAMLLSKDTSLAFLGSKKIMIDILQHI FT CRTQDIDEESAIAALEDIFETLPRNLSRDARKQIEITINHLVSRLPSIVLPFLVRRLTT FT IAGRLDRFRSTVSVSFDCLNWVNSMIPNLPEKELQYWILELLPLQSSFLSYALRDGKPS FT VADSAIKSTRRCYRSLFCKKMDSLKKLVSFLLTETENAILPPKSLPLYGVIISTCYYFH FT QSPNPRNEISQQAELFSKIMAQNVLMAKPALEKYLYHEFCYSLGLLLSVDQLKLYLLPS FT IEKALLRSPEIIFSGILSSLAHGFADSKVDASSLILSSVLTSFVNGLKSSNAEVRRNCF FT QTFKDLSANASDNESLSRVASELITSLRTGKVTASDQRVLFVDALSSLSLKHIDASMLL FT NELLPLFTKAKESDFNSLASLIVKTLKFLLMNGRNPGDKIYDFLSKSLQRPVAHESMFW FT LTSLATMAWDLPASDDVQIEFINFFLNNLSILTEKALMSVSGATQNGTYLAPIIYLSFG FT VNKLSVWNSERISHTLELQDILVKLSTPKNNDVFIFSSKITNKLNDDQSKLWYFQGLCD FT FAKVSDNLLFSNFVERWFQSVIGVFSFASRENSNRALKILKSAILYRPHLRMSICSQLW FT NYHADFEKSKSVGKFDSAKYDEISSLFQSLILSSMSADTSNFSNQELVDFDKYLVELLF FT LSFAFKDKFDWIRFCQVSKRDPATLVSERIHSIIEEIELLLSSAIKDSKETAAIASISM FT IVFVAPEESIPLFVNVFRNQLLHLNISSVSSTDLEIWKTPEGVLWDNVLEKKSSKKLDK FT NTKDYETKRWEAEVRAKQSAKKPAKLSKDQQALVDAQLDAEAKIRSRVNLIALSLERGL FT GIIRSLGEAVQLAPALWVEDAIDVLLFHNVLKYSEPFLKNLAYDTFLLTLKASGFSERL FT GDRSYSSSLASILAHTFSVNSSENIKELTKSILYKLRFAIEQNYFEPQMFACIFPLLYD FT LTFNITNSDEEDEAELQLLVTEILEFQALYSASLRRMRSKLIKSLLHLLEIAPTQYQEN FT KNSLLSLCEGLHSTYTDEELNLLLSNLFHPESSIRSAVLQALQAFDLSRFEFIKEIFLE FT LYDDNETNASIAHQISTQNGLDATETSFFELQIFFTQDSDYLQQIIGKSLIDLLDEFEE FT LGQFIPKELMRTYRENALPSAPEYDEYGIIKKETIGRDLGRIARESVAVSFFHISKYLS FT SNLLLPFLEFLLTASEAEAQIPVTDASQKVSSKMLEAGKLAIFQSGAHQVEALMELFEQ FT KLNVDSLPTDANDRLREATVVLFGTVAQHLPSNDPRLAVVMDSLLSVLSTPSESVQLAV FT AVCLPPLVKKSLGKSKEYYELLSNKLMNSTSLADQKGAAYGLAGLVKGYGIKAFQDFNI FT LDSLSELISNRQNATHRQVALFAVEAFSRILGIYFEPYLPDLLPLLLTSFGDNANEVRE FT ATMDAVKQIMSQLSAFGVKLLLPTLLDGLNEYNWRSKKASVEILGLMSYMAPKQLSVFL FT PTIIPKLSEVLTDSHSQVRNTANKSLLRFGDVISNPEIQTLVPTLLKALSDCTRYTDDA FT LEALLKTSFVHYLDPPSLALVIPILKYGLRERNAGTKRQSAKIFGLMASLTEPENLAVY FT LESLMPRLREVLIDPVPDTRATAAKALGSLIEKLGEKKFPTLIPELFNVLRSECSEVDR FT QGAAQGLSEILAGLGLARLEDVLPEILKNTSSPVPHIRESFISLLIYLPATFGSRFQPY FT LARAIPPILSGLADDSELVQTASLRAAKMIVNNYATKSVDLLLPELEKGLFDNAWRIRL FT SSVQLVGDLVFKLAGINRKALQEDEEEEGTHSDVSRKALLDIIGQERHDRILSTLYIVR FT QDIAAVVRTPAIQIWKAIVVNTPRTVREILPTLTSIIVSNLNSSSNDRRTMCVKSLGDL FT LKKAGFDVLPQLLPVLKQGLESANSGDRIGVCIALEELINSATPEQLEIYSDDFVYAVR FT RALMDGDLEVRETAAEAFDSLQSILGDRAVDDVLPQLLKLLESENQSEQALSALREIIS FT RRSSTIFPVLIPTLIKKPVSAFNARALSSLAQVAGVTLNKRLPSILNALMESSLASTGD FT DLVALNGAIDKVNLSVKDQEGLQILMAHFYSFSESEDFRKRLFAAEHMLVFFQNCKLDY FT YRYVGDWVRHFITLFEDKSQDVVVAAVAAQNTLVSALRKDQLDSLVSIAYHSLRDVGSQ FT GVNLPAFEVAQGVNSILPIFLYGLMHGTMDQREQSALGIADIVLKTEPSKLRPFVTQIT FT GPLIRIIGERFPVEVKCAILYTLNIILSKISTFLRPFLPQLQRTFAKCLGDPSSEVIRS FT RAATALGTLITLQTRLAPIITELVSGARTPDAGVRKAMLNALFAVVSKSGQNMNEASAE FT AIEQLLDEISAESSEHMVICAKLYGALFSHLPDAQAKQLLESKVLSLEIQSEFSVLILN FT AAVKFGSQKIIELKLSDIVCSIISTASLQKEVTIAENGILALGKALLADIPQSFGNAKN FT LVEALKVNIEAPPSTSQDSRRLALLIIRVVSKENYSLIKPHISILAPAIFGCVRAIVIP FT VKLAAEAAFLALFQLVEDDSVLNKYIETLEGPRARSFVDYSRRVAVKLAAAERDRINSG FT SERVKLEEVEDLAEINAVGRDNEVSTNDP" FT misc_feature complement(19218..19234) FT /note="splice branch and acceptor sequence, ctaacttttcatttc FT ag" FT intron complement(19218..19290) FT /note="confirmed intron" FT misc_feature complement(19285..19290) FT /note="splice donor sequence, gtaatt" FT CDS 21113..21862 FT /db_xref="SWISS-PROT:Q10106" FT /label=SPAC18G6.06 FT /note="SPAC18G6.06, len:249aa; similarity: to hypothetical FT proteins C. elegans WP:C16C10.2 CE01493 (31.5% identity in FT 260 aa overlap) and budding yeast SW:YKJ9_YEAST P34247 (3 FT 7.5% identity in 248 aa overlap)" FT /gene="SPAC18G6.06" FT /product="hypothetical protein" FT /protein_id="CAA92386.1" FT /translation="MSSSFKNAGQRKNHRERAQPFERRKWGLLEKRKDYAQRAQDYKTK FT QKKLKRLREKALERNPDEFYHEMTHKKTKNGVPLEQREDSTIDMDTIKILKTQDIGWIR FT HHRNVERAKIDHLEQQMHTVGAHRNKNESRKHTIFVDNVKEAKSFNPAEFFQTTDDLVG FT RTENRVKKDQIENNELTNQPFSGKLHSKLKEKAATELLLRQKRDKKLAAAEERVELDRL FT LQGKGGRQKKKVVNGKPVYKWRNERKR" FT CDS complement(22431..23510) FT /db_xref="GOA:Q10107" FT /db_xref="SWISS-PROT:Q10107" FT /label=mra1 FT /note="SPAC18G6.07c, len:316aa" FT /gene="mra1" FT /gene="SPAC18G6.07c" FT /function="required for cell growth and mating" FT /product="downstream factor of ras" FT /protein_id="CAA92394.1" FT /translation="MPTYSKRKSRGSLEVSEKTNQPKFIKRSQSSETITSGETASELMQ FT DEKEQSNGAVGSIEDEELQRLRENQASVEALSKKPESIDRELGVEALEIDNVVKSDEEK FT EDPNGASSKTVKARPLPAGSVHRVTTHMAPIPARSIGSHDTTTQRLIVVLDQACLEIYK FT VGKAKDAKYQLLNCDDHQGILKKLNRNIAQARPDITHQCLLTLLDSPLNKAGRLQVYIH FT TAKKVLIEVNPSVRIPRTFKRFSGLMVQLLHKLSIRSVNGNEKLLKVIKNPVTDYLPPN FT CRKATLSFDAPTVPPRKYLETLQPNQSVCIAIGAMAHGPDDFSDGWVDEKISISDYPLS FT ASIACSKFLHSMEDFLGIV" FT CDS complement(25247..26185) FT /db_xref="SWISS-PROT:Q10108" FT /label=SPAC18G6.09c FT /note="SPAC18G6.09c, len:312aa" FT /gene="SPAC18G6.09c" FT /product="hypothetical protein" FT /protein_id="CAA92387.1" FT /translation="MQKDIGRRFQRNKKKINSKPGGAMVASSDVEFSLDGMSIMPQRDG FT NLQIPNFVKPKSTFATSNIGESNGKRNGDKVRGNRRSKSGHSSYAGSRISGGNSNSHLP FT SGVASAPAGLGIDKVAVGEVDSHLKSVSSYVSNSSGADRSFSSNSSSDTNSILYAGPTF FT THSPAASNLPIPTFLHSPVSEKAEWQPPTGSVNSNMPFQFHQSSSVPSTPSEVAMGHNF FT CPMSRNDPSLQSIQQTNGFYSGHNSPHTNYSASTPSFNHFNAAGHPTGNITPTLNSPNN FT GIHCHSTSALDLLFHRDREQRLFRMLRQGSA" FT CDS 26696..28762 FT /db_xref="GOA:Q10109" FT /db_xref="SWISS-PROT:Q10109" FT /label=SPAC18G6.10 FT /note="SPAC18G6.10, len:688aa; similarity: to YDR458C, YD58 FT _YEAST, hypothetical protein, (663aa), fasta scores, opt:19 FT 0, E():3e-10, (23.8% identity in 705 aa overlap)" FT /gene="SPAC18G6.10" FT /product="hypothetical protein" FT /protein_id="CAA92388.1" FT /translation="MDNWEDPNFELRNLRVIDLKKILHESGVSFPVNARKIEYIRMVDR FT IRKNKLSSGPQHLLSHLQKEENSNTSKASSSEDEIAPKYLYPSSPSKSTKKPHNETEPL FT LSPQFIDKPSNIETPVKIESPHVSQNNTFQSYSELSPNVETSLTMKTPPAHASTPKFRS FT HKSHRVAVPMSFMDSSALHTSPAFSERLKLLSSSNNFSPQLRSPKISHRLQTSATSSPL FT QHKRPFTNVPERVSRDIEFAPLDSARPSESSSPYSEVDSAEEDDELFQNYVLQQTRKES FT KLWSFIKKVFHDIKYANYRLLHNLRAFPGISAISSSYLVHIFMILLGVVAAIFLALLRE FT KMFTAGFCDSGASGSSASILGISFPSLCRTCPPNAICPSPNYVECKPGYVLYEPWYSSL FT GFWPSKYCVSDTSREESVNIFREECLSVLRSWNAILHCSNNSSDLLERNMSYNAHPYVA FT DNLNISSDHISFPSKPFALGLLHDTLLERKSPTLGLEMFEDLFKASLAVLSETNEVVMD FT SKLICYDSWAGIPLRCRLKQQLIKFVWRNKVFLFGILALSGVIFKLINFFRTRSIVAKY FT LPSASRFCVESLKRQKANYQMSRSQEPVIPLIEMHDILFHGNGPLEQIHMTKATARTLW FT EAIVERVEQVGSVRTRESEVDGEWTRVWEWVGTNTLDFQTDRSFINTTSPLRE" FT CDS complement(29094..30893) FT /db_xref="SWISS-PROT:Q10110" FT /label=SPAC18G6.11c FT /note="SPAC18G6.11c, len:599aa; similarity: to YKL125W, RRN FT 3_YEAST, P36070, rna polymerase i specific transcription in FT ititation factor, (627aa), fasta scores, opt:274, E():5.8e- FT 33, (26.9% identity in 590 aa overlap)" FT /gene="SPAC18G6.11c" FT /product="rna polymerase i specific transcription initiati FT on factor" FT /protein_id="CAA92389.1" FT /translation="MPSIISSTNPQYINKCVNNGTMASSTNVPDRTVGSKSFASSVSKN FT DGRLMQQMLRAFVNKALDDKAEGNFAGYEDLRRQFAAKSDTKDAPSSLQLQNLLSALTC FT NVSRLDSSNSSLVMSVLDSVWVSRDESFVRCYTRFLGNLISAQSNYLPLVMTMLIQHML FT YRPDSLAIHYEHAHMALKYVLELVPRAHSFLYSSILEEFPYKDESLLAQMTYISNVLSI FT CEYVPSIKGPVLHAIIDKIIQIDVEIQVEVDDDDEEEDEVVTDDDGTSNADSEVITAST FT LYERHTAISSEMTSSTILTPPSLTDTRQLMQQLDQLLYTLFSYLDSNLKSTSRDRYLVY FT NSLIKSFVNTVLKTFRCRYTQFLIFWASQLDPEFTDIFLGVLTEVCLDPSQPYTLRLSG FT AMYIGSYVARAKALEKNTIQIIVNMMTRWVEAYLDQCENELSDDLLSKHSVFYAINQSI FT FYIFCFRWRELCVSDESESMEPRPNEWIPGLEILHRSVLSRLNPLRYCSPNIVLQFAKV FT ANHLNFMYVYSIIEQNRKGIFREGFDTMDAYFPFDPYRLTKSSIIVQPFYNEWQQIPGL FT DDDEEEEDTDYESSTVMLGESPF" FT CDS complement(31599..32528) FT /db_xref="SWISS-PROT:Q10111" FT /label=SPAC18G6.12c FT /note="SPAC18G6.12c, len:309" FT /gene="SPAC18G6.12c" FT /product="hypothetical protein" FT /protein_id="CAA92390.1" FT /translation="MAFSFQVSKMNSFDNYNAAIHPKHDLISVNAPVFGKDAKLSPHLA FT IVLADKGFMLEQVCLPWRYFTDRGFVVEFVIAESIFPPRPPKPNDSYMTGWKSHVLGAS FT KEILDIYSVLCTLNEFNNPKCYRSNGFTFDNFSAVFITGGRNPFVREMLEDPLLHASLV FT PYIHSCRTIQPDEEVKDNRKIKVLGAISQGAAAIYLAEPNINMKTTTIPAWMERSNSFL FT NPTPDNSTYPYAATIIPKDKYVSGPYRRVAFTYQDENYYYISGRSNKDIGELSKKMYLM FT YKQAYKDLNASLRERRRRSTSNRRNSGI" FT CDS 33111..33455 FT /db_xref="SWISS-PROT:Q10112" FT /label=SPAC18G6.13 FT /note="SPAC18G6.13, len:114" FT /gene="SPAC18G6.13" FT /product="hypothetical protein" FT /protein_id="CAA92391.1" FT /translation="MRLKVSCTEFPIQQWVETSSLELVDSVNCVADLCHAIWMFNGGCA FT DWRLQILKEGFTVPMTGIISQYLKTDDHIKIVKEIYPPNLPVLPFRVYTTQNTSVESEL FT VEWEDVEMEA" FT CDS complement(34034..34621) FT /db_xref="GOA:Q10101" FT /db_xref="SWISS-PROT:Q10101" FT /label=rps7 FT /note="SPAC18G6.14c, len:195aa" FT /gene="rps7" FT /gene="SPAC18G6.14c" FT /product="40S ribosomal protein" FT /protein_id="CAA92393.1" FT /translation="MSALNKIVKRSSSQPTETDLLVAQCLYDLESSSKDMAKELRPLQI FT TSAREVEVGGGKKAIVVFVPQPLLKAFHKCQARLTRELEKKFADRHVIFIAQRRILPKP FT GRKSRVTQKRPRSRTLTAVHNAILEDIVFPTEIIGKRTRQATDGRKTIKVFLDNRDANT FT VDYKLGSFSSVYHKLTGKNVTFEFPVATGEGL" FT misc_feature complement(34046..34615) FT /note="Match to PF01251 Ribosomal_S7e, Ribosomal protein FT S7e Score 492.65" FT promoter complement(34670..34677) FT /note="Homol D box" FT CDS join(35734..35775,35836..36720) FT /db_xref="GOA:Q10113" FT /db_xref="SWISS-PROT:Q10113" FT /label=mal3 FT /note="SPAC18G6.15, len:308aa" FT /gene="mal3" FT /gene="SPAC18G6.15" FT /product="putative chromosome segregation protein" FT /function="probable involvement in chromosome segregation" FT /protein_id="CAA92392.1" FT /translation="MSESRQELLAWINQVTSLGLTRIEDCGKGYAMIQIFDSIYQDIPL FT KKVNFECNNEYQYINNWKVLQQVFLKKGIDKVVDPERLSRCKMQDNLEFVQWAKRFWDQ FT YYPGGDYDALARRGNRGPANTRVMNSSAGATGPSRRRQVSSGSSTPSMTKSSANNNNVS FT STANTAAVLRAKQAQQQITSLETQLYEVNETMFGLERERDFYFNKLREIEILVQTHLTT FT SPMSMENMLERIQAILYSTEDGFELPPDQPADLTTALTDHDTNNVAEEAQMTDLKDSET FT QRVPSAPDFVHARLQSLEVDDDENITF" FT misc_feature 35776..35781 FT /note="splice donor sequence, gtacgc" FT misc_feature 35820..35835 FT /note="splice branch and acceptor sequence, ctgacttattttaaa FT g" FT misc_feature 37525..37621 FT /note="nominal overlap with cosmid SPAC13D6, EM:Z69725 S. FT pombe chromosome 1" XX SQ Sequence 37621 BP; 12471 A; 6904 C; 6735 G; 11511 T; 0 other; gatcctttcc agcctttgtc ttttcgtgaa tccaacttgg aacagaagca ggagatgagt 60 tttttgaacc atcataacct tttggagttc caggctcagt ctttgcagga tcatcctgca 120 tggggtctga agactgccca gcttgcacag catttgaaag aagtgacaaa gaccctgaac 180 gctgttgcat cattttaatc cccacactga attctaaata ataaaatcct gtgcgactaa 240 gactgcaacc ggtcccctaa aaaaaaagac gttccttatt atatatagat gtgtggacct 300 gttgagtata gtggcgtgct aaggaaaagt tgtgactata tcgccaactt gttgatagtg 360 agtgctagag ttgtccagta agcgagcttt taatagtttg ccctacactt tccataagta 420 aacactatgg aaaaaacaga cgacacgcca cccaatacta gctctataaa aacagaaaaa 480 aggatggtta ccatcaaatg tagcgtgttg aaatcaaagt gcctttcagt cgttgtcttt 540 tgctcaaata ccatttgaaa attaacgtaa tacagtgtaa tgctaagtag ttagttatat 600 agaaaaatag taaacataaa aaagaagagg ttgcatataa agaataaaaa aagttattta 660 tttaagagac actagaaaaa taatgacttt tgtccaaatt atttttggtt ggttttgaaa 720 ctaggataat tactttttgg aataattatg aatgtatgta actattgaga aaaacaagaa 780 aactaaaagg aattgaacga aacgaaggat aatagttttt tatatctaac tcctttaacc 840 ttcatccttc aatttttttt gattcttctt agcgacaggc aaacttttca actatgagaa 900 tatcgatttg ccaattcgct ttgacttttg tgccgtacat tcgctagaat gtttgtacga 960 tacaattctt atgtaaaaaa aatttcgcaa agccgtttgt aaaattgctc aagctcttcc 1020 aaatgtgtga attattataa tacagaaata gatacgtttt taaaaccttg aaagctgcaa 1080 ctatacgatt tagcccaata aaataaagtt tcttttgttt ctattctttt tttttattca 1140 tctttaagaa aaacaaattt gaaaagcaat tagataattg tcacaatttc tatagaaata 1200 agattaaggg atacagcatt ttaaactcac tatctatgac tgaattaaag gctgtgaacg 1260 gagcacttgg tgcctggtgc tagaagatgg acagtctaaa acacatgtta cctggactga 1320 aaaaaaatat tcgtaaacgt tacaagtaaa tggggaatgg tgaaaatcaa aaagcaaatt 1380 ctattaattt cattgtttaa aaaatgtgca cctggtgtaa tagggttaaa cttggaacat 1440 cgcttctatc gtaaagtctt aaaactagtt agaagggaat gaagaaaaca ttcaaatctc 1500 ctatttgtaa cgtcaaaatt aacatgacac gtagtgctca aaaatatcat cgagtttaat 1560 ttttaaatgc cttagtttat tagcagcaca ttttatagaa ccgaaaaaaa gctatattcg 1620 tcacaggaat tgttcaacgg taattcaaaa tggcctagtt taaatagttc attttctttt 1680 cattaaaata aaacatctaa gcgtaatata aggaaatttc cttagaaaga ctaaagaagt 1740 ttagtcaacc aaattaacat cattcattcc tcagtcagtg gatgaaaaga attagtgccc 1800 accaaaaatt gtgcaaaaag agcaaatgaa atactttatc aaagagtatt catttaattt 1860 gtcatcaaat cctgatcgta tggcttcgca caaccatgac aacgaactaa gaaaaaatgg 1920 aaccactttt atacgtggct tacacaaacg ggtatctaac gttgggcgct gtattcgtgt 1980 atggtatttt ttatcaaaat aaaagtgttc catccatgat acgtcgcaat gtcaagcata 2040 cagattcccg agcttgctca ctgtttactc tgggcccaac tagataaccc tttaggaaga 2100 gattagagac catatagttc tcatcatgca tatggccaat ttccgaatcc ttatatatat 2160 aacaaaaatc gtttccatac aatttcatcc atagtgcggt ttccttgaag caagttcgat 2220 ttactggaaa tgtgctacga aatttgctta ctgctgcttg ctccgcagga tcgttttgag 2280 acattctcga ttgaaggcca cgtacaaacc ctcctctcaa gtggctaaaa ttggtatttc 2340 tagtgggaac gattttaatg gcatacttca tttcgttttt caatagcgct gccacgatcc 2400 gacttccaat ttcttcgtct ttcatactca tttctagccc taatttcgga tctacctcct 2460 tttgcaatat agtgtgaacg gtttgaacat ctttcttctg aatatacaat tcgatatcat 2520 acacatgaat acttagaaaa gaaacatatc gcggtcctga acctaacaaa aatagttcat 2580 cctcattatt aattcttttt tgaactaatc cttcgtatgt ttgttgaatt gtcttggtga 2640 cactctcaca gtatagaggg cgagtttgat acatggcatt tattgttgct actgagctcc 2700 aaaagaccaa tcctggtcgt ttcgataacc aattcttgca aaattgataa gcaaaaaaac 2760 gagtaccaaa catgttgttt agtttaaata cacacacaca gatattagcc ggttggtatt 2820 ggatcacatg tttttccaag agatcctaga ttttaaggag gtgcgcaaaa acaactaaca 2880 atgttgaaac atacggttat tatatagtga aaaaattaat taattaatta atcgtctaat 2940 ttctaaagag tagactgtta ttttctagta taagtctttg agtttaattt taagtattcc 3000 tatccattcg taataagaaa aaatgtcagt ctatatatcc cattgtccgc cgtatcccaa 3060 aataaataaa acgactattt taaaccaata gctctcataa aagtctcttt gaactcatca 3120 tagtcaacaa tgtcaaggcc attaactggc gtcaattcat ttttaagctc gtgaatcaat 3180 acgaaccttc tatatttatc ataatttttt ttctggtaca attgtagagt gctggctaaa 3240 gatacatcag cgctatcatc gatcacaata tcccaatcct gatacaaagt cacgttcttc 3300 agcgctgggt tggtcaggta gcgctggagt gtattcaata agttttgaat ttccaagaga 3360 cttttgtctg gattgtttgt tacaaaatag ctcttgacca tatccacaat tgatgggggt 3420 agaattaaaa tccatgaatc ttttttaatc tcaagaaatg gactaatgag ttccaaaagc 3480 cgtggtgttt ttataagtgc tgagagtgta acagatacca ccccaccctt aggaaacatc 3540 ggtcttaagt actgtgaata tgtcaactta tcaaggggtt cattgttttt cttaaagtcc 3600 gtacccacgt gtgaatcatt aggacttttg agagggagtg acaaaccaaa taagaaaaat 3660 ttacaacttt tccttttcgc cagtgttaaa aattgcagtt gatcaaaatc atcctctagt 3720 gagacattca ggaaaacaaa aacattctgt gataaaaaca aagattccgg aatctcgagt 3780 cctcgaaatg tcggaatagc agcttctcta aaagtatcct ccaattcttc tgcctccgga 3840 gaaggctgtt tagagacaat taaaatttgt gtagcttgaa aagcgcctat tttatgtaaa 3900 tcgatgtggc ctaattgtag taaataagac aagtaagatt gggatttatg atatggcttt 3960 ttaggcctta gattttttgc cgaccattcg actaggattg attctaaagg ttcaaaaatc 4020 accatccaaa aagggctatt gctttggcct tgacaatcgt ataaattcat taaagcatta 4080 ttatcctctg taaataataa taatgtatag ttactaccca gaacgatgcc agcaccgttg 4140 ccgcggttta gtatattttt aaagtgagtc atatcaacat cgcttcgaat acaaagactt 4200 ccggaaagaa ctttagtcaa gcaagtacca aatacctcga gatattgtga agtaacaaaa 4260 cgtaaaacat ctacttgctt gcaactgact aaacttcgta acaactgttg atgttcagtt 4320 tccgccttaa gcttggatat atcaaatgac aattctccag catagtagag agattttccg 4380 actcgcaaaa cgaatctaaa ataatcagac aatgtgcttg ctgaagaaag atcttcggat 4440 tcgcttatcg aatggtgaag agagttatcc gaatttaaag taatattacc agccggaact 4500 actttgctag ctccatcatt ttcaaaagtt tgatcgcttt tagaaacact gttccagtcg 4560 ttattaacag tagtccaact acttccgata acacttttct taagctgctt agcatcttca 4620 ttcgtcacgt ttacgttgaa atcgaaattt tcgtccagat cgacattgct agcaaatttt 4680 tccgactcag aaagggtatc tgttgttgtt tgtgtaaaag aaacggacct tgcatttgct 4740 ttctttgaag gggttgtttt taaaatagac tttgagactt tacattcttc catatcagtt 4800 gatatcttcc cttttactaa agttacatgc caacttggat gccctttatc atacgcaagt 4860 ttggcttgtt cgatagaatc gaattgaatg taggccatat tacaaacttt gtctttcttt 4920 ggtgatttga gaaaaaagac ctcaatattt cctttgataa aagcaaagta cgataaaata 4980 tcttgcttcg ttaaagaacc agaattatca ctaactaata tcgtatgcgt ttctaatttc 5040 ggtgcttcct tttttatctt caaagaggaa ggaagaggag tcgaattgct aaaaaataat 5100 gaattggcaa catcattatc ggaagttatt actggcgaca gacttaaagg gcttgaatgc 5160 ctaaaggttg acaagggggt gttagattgt ggtgaattcg cattttcaac aaaagcgcca 5220 gtattttcaa gattgttcga attttgaatt ccgggaactg agttgtcaga gtcactgggc 5280 atcaacattg tgcttttaat ttcgccattt ttcaaaggta ttgcatcgct ggagaggctt 5340 ttggacaata aaatactgtc ggtaactgta ggccactctg ataagtagaa aggattaaca 5400 tcagggctag tttcaccaaa cgatgtggat agcgtgctag ttttatcggt caaattcctc 5460 tccttcaatt ccccttgcat actttttctc tcaaacgcat cctcatccat tgtctgatcg 5520 tcctcttcct cttcatcatt tgcgatggtt acaatccttc gggcaggctt cttacgcatc 5580 tttttgaatt tttctttgac tttttgagat aattgggtaa gctcggattt gcgcttttgt 5640 ctttgttgcc tcaatatctc cttttctctc ttcattttct ttgcctcatt atcttccgca 5700 tcgaaaggtt caagcaagcc tttagcaatt aactttttcc gttttttcca ttttttaagc 5760 actttttccg caccgaataa attttgttca ggttcccaag tattatcata ccaatcatag 5820 ccagcccatt ttatataata ttcgtttatg ccatttttat ttacgcggtc agcaaggata 5880 tcttccacct cataaacatc cgcgtctgtc tcaccttcat tcgagtcaat atcaggaagt 5940 ggtttaacag ataccatttc aaggtagcgg gttttttgct cacctacgtg tcgctaagag 6000 agattgaagt attacaacaa aaaaatatat aaaaggataa agatatgaat ttaaaaaaaa 6060 aacggaatta agcaagattg aatagattcc ttgacaaaac tattagccaa agttcttccc 6120 tttcaactac ttttatagtt gcatgaaggg cagagtataa cctctaaaat ggctcaaata 6180 tttccctttt gcttgtgatt tttttaccaa tggaacacaa gaataacaac agataattcc 6240 agtaatgaag cttttagatg ttagaatttc gaagtctcgc tgcaataagc aagatggctt 6300 atgcactcga attttggaat caaacaaaat ccgcgtgatt ttaccgtcgt gtcaccaacg 6360 caaaccgtta aatatacaaa aaaataagtt ttcgattggg tttggagttt tattgcatta 6420 atcaagtgtg tgaggttgag gttgcagatt tgaagacacc tatggagaca tatgtacttt 6480 gagaaaatac tcactaacca ctagtgttac tagttgcata catgaggtac tagtagtcaa 6540 aaaactttgt tggtaaattg ataaatgttt aaaattttct cattcctcct gaacttctaa 6600 ttttattttc tgggtggttg tgtaagttag aaaaacttta aacaaataat gaattttgtt 6660 ttcaaaaagc tacaatgagt agattttgag cgctgcaatt tattaaacga tgcgtttata 6720 cataatacct ctaaatgtgt taactctata taaacgaatt caacacaaca tatcattcca 6780 aaactggtag tacaataaga aaagtaaata attactacga tagaaaaaaa tgatcgtgcc 6840 aagactcgaa cttgggaccg tctgcgaact agcatgttaa gcagaaatta taaccatcta 6900 aaccacacga cctcttttga taattgcttg cattaatttt atatagaggt taaccaaggg 6960 atccatttac ttatattatt acggaactat gttattcgtt ttccatgaaa tgaacttaat 7020 aagaaaaact gtttatgtgc aggatttttt tgtttcttgt taacccaaga tttgccaacg 7080 ataattattc gatggattac tcaagtaact ttctgcatga aggatgcctg catgccatga 7140 gcagcatcca acattgtata acttttgcat aaagaaaaag atttcaattg agccgccaat 7200 tttattcttt caaattttta atttcgatca ttgtgaccat tataaaagtg agaaaaagct 7260 gctgaaaaaa ccggaactta aaatattctt tctttggcta gataactttg taacttggaa 7320 atcaaaacat tgctttcaaa gaatttctac atcattgttt gatgcaggac taaaatgggt 7380 atagtactga ctaatcgcac tgtaaaaacc cataccaacc cgtccatatc cagttttgcg 7440 attgggttca atcggtcatt catataattg atagtacttg cattcaattg agtacttgcg 7500 cttctttata tcaaaggcat tttaaaatgt ttacaaaata gcgctttata gtgaacaaca 7560 gcataatgat tttgatgata gcaatcacta aacgacacca gccttctcat gattacgaca 7620 ttctttgtaa cgcagtataa ttatttaatg aatcattgga atgcgttata tgcattttaa 7680 cggccagtgg cactagtgga cttttttttg ttaccatgat aaaggattat tacttcctta 7740 ggttttctga tatccctctg caacttacct acaacaaact acgactaagt aaattcttcg 7800 actatcgaaa gcagggttca ttgtaattta caggtatata ccttgatatt atttgacctt 7860 aaatatttgt taacaaaaat tgttcgtaga tttaccgata gagaacttag ccatgtgtca 7920 agaggacgaa tacgattatt tgttcaagac tgtgctgatt ggggatagtg gtgttggaaa 7980 gtcaaaccta cttatgcgtt tcactaggaa tgaatttaat atcgaaagca agagtactat 8040 tggtgttgaa tttgctacta gaaatattgt tcttgacaac aaaaaaatta aagcacagat 8100 ctgggatact gccggtcagg aacgttatcg ggccattacc tcagcttatt accgtggtgc 8160 tgttggtgct ctgattgttt acgatatcac aaaacaatct tcattcgata atgtgggccg 8220 ctggttaaag gagcttcgtg agcatgcaga cagcaacatc gttatcatgc ttgttggtaa 8280 taaaacggat ttactacatt taagagctgt atctactgaa gaagcccagg catttgctgg 8340 taagtaattt tgttggtgag atatggagtt gttcggacgg gaagtagtga aaccggcttt 8400 agccgctctc actttattcc gttcatcgtt tttagcaatt ttgaactgct tgaagcgtag 8460 aagatctctt tttgttttga aatattattc accttgtcga ttccattctc tgtttattaa 8520 gcacatttgt ttgcctctga ttcgtcataa ttttttgaac ataattaact aatgttttta 8580 cagctgaaaa taacttatct tttattgaaa cctccgccat ggatgctagc aatgttgaag 8640 aagctttcca aacagttttg actggtatgt ttattcgtac ttgctttgat ttcttcaagt 8700 tttactaatc tagcgtagaa attttccgaa ttgtctccaa cagatcactc gaggctggag 8760 acgacggtgt tcatcctaca gctggtcaaa cgcttaatat cgcccctacc atgaatgatc 8820 ttaataagaa gaagtcttct tcccaatgtt gttagatggt tatcacggat tcgtaccatt 8880 attttacctc gtttctcttc atttaaaaac tccacccctt tataacattt aaggtgcctt 8940 atgattatga aatctttagc aggttagtca accatttatt agggctgtat cctttaataa 9000 aggggtagat attttgccta atgctaatat tgtctactat ggatttaccg tccttcttta 9060 tacacgcttc agcataattt tatccccatt cctatgcagc atataagtgt aacacattat 9120 tacctctgtt tattatatga tatttgtagg gttactttaa tagagaattt gtccagatat 9180 tttcattatt catacagctc atgtttaatt tccatgatat atcctttata agagaaagta 9240 acagatgata agtatgagat aagagccaaa aagttagaga cagcttaaac ggggaaatca 9300 aattttccag cccaagttat aacttctttc ttcagtttgg cgatttcaga gaatttagaa 9360 ccatcaccca catatgcttt gaagtctcta aacttcgatt ttccttcctt caaagcagct 9420 tcatttattt tcttggtcaa agatacaact tcatcaatta gctctaccac tctctcaaaa 9480 tccttctcat caaaaccgcg agtagtgcaa gctggagttc ccagacgtaa tccacgtgga 9540 attaaagcag acttatctcc gggcacagta ttcttgttgg cagaaatatt tacaagctct 9600 aaaatacgtt cgacacgggc accatctaca cctttgtcgg tcaaatcaac aagaaccaag 9660 tgagtatccg tgccacctga aactaactta tagccacgag taataaatgc attggccatt 9720 gccttggcgt tacttagaac gtccttttgg tattgataga attcaggagt ttttgcttgt 9780 ccaagggcga cagctaacgc agtaattgta tgattatggg ggccgccttg atgtccagga 9840 aaaactgaga aattgatttt atcctctaat tcatataaaa ttggattacc acgtttatcg 9900 tgagaacgag taccttttcg ataaaatatc atagctcctc tcggtccacg taaagactta 9960 tgagtcgtcg tagtaacaat atcggcgtat tcaaacggag aaggaattac accggcagct 10020 actaaaccgg atatgtgagc catatcacaa agcaaatagg cattgcacat ttccgtaatt 10080 ttacgcatac gcttgtaatc aacgagtcgt gcataagcac tagcgcctgc aactataact 10140 ttaggacgaa attgtatcgc agccttttcc aaactatcat agtcaataat accagtttcc 10200 ttatttacgt tatatggcat ggtggaaaaa taagtcgaga cagctgaaat agctttctgg 10260 ggagtagaga aaccatgaga taaatgaccg ccatggggta aatctaaacc cattaggcga 10320 tcgtgtggct tcattactgc ttgataagcc tgtaagttgg ccggagaccc agaatggggt 10380 tgtacattta ctccccattt ttccccatcc aaatgaaaag cttctaaagc tctcgtttga 10440 catagtcttt cagcttgatc tataaattca ttaccaccat aatatcttgc accaggatag 10500 ccttcactat atttgttttg cataatactt ccgagtgcat ccatcacagc tcttgaagta 10560 aagttttcgc tagcaattaa agctatcgac tctttctgac ggcttttctc agattccaaa 10620 atcttataca ctgtcggatc acattctgcc aatggtgctt tgagtaactt aattatcgtt 10680 agaactttat tagaacactt cataaatcat ttgagcaagt caatctatcg cctgttgata 10740 gtagcaaaca gcacagatag aaaatacagt cattgcttgc tccaaaaaag cgcgtttaaa 10800 taaacttctt tacctttttt tgattagcag aaagcgcata aaagcgcttg ggaattgaag 10860 agtaagagtt cttgacgaat tgacgaagaa ctgccattgt ggtgataggt aaggtgtcct 10920 aaaactgaaa gataaagttg ataaaattta agtagaactt ggcgcgtccg aaaaactttt 10980 acaaactaaa gtttaataac aataaagaat attaaactat taggtgggtc aaattagaaa 11040 attccttttg gaaagttcta cttcgcaaat atttacccca aagtaagtac tatgatattg 11100 aaagtaaaaa gtaaataaag atgtctttct ttattaagtt tacacattta taacacaaag 11160 tcattaattt ctgatattgt aactaaatct gatacgaaac tgaagtttaa aattgctaca 11220 ccatatattg atatcgtcaa cactttacag agatatttta taaacaaaat gttttcattc 11280 atctataccc aatctttttt aacgttacaa ctcaaaacat gaattggagt acttccaaat 11340 tttgagttgg gattaaggat cattagtgga aacttcattg tcccgtccta cagcattgat 11400 ttccgcaaga tcctcaacct cttctagttt tactcgctca ctgccagaat ttatacggtc 11460 acgttcggca gctgctaatt tcacggcaac tctacgactg tagtcaacaa aacttcttgc 11520 tcttggccct tctagtgtct caatatactt gtttaaaaca ctgtcatctt caaccaattg 11580 gaacaaagcc aaaaatgcag cttctgctgc aagttttacg ggaatcacaa tggccctaac 11640 acaaccgaat atcgcaggag ctagaatgga aatatgtggt ttaataagac tataattttc 11700 cttgctcaca acccttatga ttaaaagtgc gagacgtcgt gaatcttgag aagttgaagg 11760 tggagcctcg atgttaacct tcagtgcctc aactaaattc ttggcatttc cgaaactctg 11820 tggaatatca gccaaaagtg ctttaccaag agccaaaata ccattttcag caattgtaac 11880 ttccttctgt aaactcgcag ttgagataat cgaacaaact atgtctgata acttcaactc 11940 aataattttt tgagaaccaa acttcacagc agcattcaat atcagtaccg aaaattcaga 12000 ctgaatctct aaactcaaaa ccttactttc taacagctgc tttgcttgag cgtcaggtag 12060 atgactgaat aatgcaccgt ataacttggc gcaaattacc atgtgttcac tactttctgc 12120 agatatttcg tcaaggagct gttcaatggc ttctgcggat gcttcattca tattctgccc 12180 agactttgaa acaacagcaa aaagtgcgtt aagcatagcc ttacgaacac ccgcatcggg 12240 agtccgtgca ccagatacaa gctccgtgat aatgggagca agtcttgttt gtaaggtaat 12300 cagagttcct aatgctgttg ctgcacgact ccgaatgact tcgctagatg gatcacccaa 12360 acattttgca aatgtcctct gcaattgggg caaaaacggg cgcaaaaatg tagagatttt 12420 agataaaata atattaagcg tatacagaat agcgcactta acctcgaccg ggaatcgttc 12480 accaataata cgaattaatg gtcctgttat ttgagtaaca aaaggacgaa gtttgcttgg 12540 ttcagtcttt aaaacaatgt ctgcaatacc taaagcagat tgttctcgct gatccattgt 12600 tccatgcatt aatccgtaaa ggaaaatagg taaaatggaa ttgacgccct gagcaacttc 12660 aaacgccgga agattaacgc cttgagatcc cacatcgcga aggctatgat aggcaattga 12720 aactaaagaa tccaactggt ctttgcgaag agccgaaaca agagtattct gagcagcaac 12780 tgcagcaacc acaacatctt gactcttgtc ttcgaagaga gtaataaaat gtctaaccca 12840 gtccccaacg tacctatagt aatcgagttt acagttttgg aaaaagacta gcatatgctc 12900 agcagcaaat aatctctttc tgaaatcttc actttcagaa aacgagtaaa aatgagccat 12960 aagaatttgg agtccttctt gatccttcac agacaaatta actttatcaa ttgctccatt 13020 caaagcaaca agatcatctc cagttgaagc tagagaagat tccattagcg catttagaat 13080 ggaaggtaat cttttattca aggttacacc agcaacttga gccaaagatg ataaagcacg 13140 agcattgaaa gcagaaacag gttttttaat aagagtaggg atgagaacag gaaatatagt 13200 tgatgatcgt cgggaaatta tctctctaag ggctgaaagt gcttgctcag attgattttc 13260 tgattcaagt aacttaagta attgcggtaa cacatcatca acagctctat ctcctaaaat 13320 actttggagt gaatcgaatg cctcagcagc agtttcccta acttctaaat caccatccat 13380 aagggctcga cgtacagcat aaacaaaatc atcactgtat atttccaact gttcaggcgt 13440 agcactgttt attagctctt caagagcaat acatactcca atacgatcac cactgttagc 13500 tgattcaagt ccttgtttca aaacaggaag gagctgtggc aaaacatcaa aaccagcctt 13560 cttcaataaa tcacccaaac tctttacaca cattgttctg cggtcattac tcgagctatt 13620 taaattgctg acgataatag aagtaagagt tggcaaaatt tccctaacag tacgaggagt 13680 gttaactaca attgctttcc atatctgtat ggctggagtt cgaacaactg cagcaatgtc 13740 ttgtcgaaca atgtagagag tcgagagaat acgatcatgt ctttcttggc caataatgtc 13800 aagcaatgct ttacggctaa catcactgtg tgtaccctct tcctcctcat cttcttgcaa 13860 agccttcctg ttaataccag ccaatttaaa gacaagatca ccaacaagtt gtaccgatga 13920 tagacgaatg cgccaggcat tgtcaaatag gcctttctct aattccggta acaacaaatc 13980 aacagatttg gtagcgtaat tgttcactat catcttggca gctctcaaag aagctgtctg 14040 aacaagttca gagtcatcag ccaagccaga cagaatgggc ggtatagccc gagccaaata 14100 gggttgaaaa cgtgatccaa aggtggcggg caaataaatg agcaatgaaa taaaactttc 14160 acggatatgt ggaacagggc tagaagtgtt cttcaatatt tctggtagaa cgtcttctaa 14220 acgagccaaa ccgagaccag ccagtatttc tgataatcct tgagcggcac cctggcgatc 14280 aacttcacta cattcactgc gaagaacatt gaaaagttca gggataagcg ttggaaattt 14340 cttttcccct aatttttcta tcagtgagcc taaggcctta gcggctgttg cacgggtatc 14400 tggaacggga tctatcaaaa cctcgcgaag tctaggcatc aatgattcca aataaacagc 14460 caaattctcg ggttctgtca agcttgccat caagccaaag atcttggctg attgacgttt 14520 cgtgcctgca tttcgctctc tcagcccata tttgagaatt ggtattacaa gcgccaaaga 14580 gggtggatca agatagtgaa caaatgatgt tttcaacaac gcctccaacg cgtcgtctgt 14640 ataacgtgta caatcggata acgcctttaa taacgtagga actaaagttt gaatctcagg 14700 gttcgagatt acgtcgccaa atcgaagaag actcttattt gctgtatttc taacttgaga 14760 atgggagtca gttagtactt cgcttaattt aggaataatc gttgggagaa aaaccgacaa 14820 ctgctttgga gccatatagg acatcaaacc aagaatctct acagaagctt tctttgaccg 14880 ccagttatac tcattcaatc cgtccaacaa agtcgggagt agaagcttaa ctccaaatgc 14940 actcagttgg ctcatgatct gcttaacagc gtccatagtt gcctctcgca cttcattagc 15000 attatctcca aaggaagtta aaagcaacgg taataaatca ggcaaataag gctcgaaata 15060 aatacctaaa atcctagaga acgcttcaac agcaaaaaga gctacctgtc gatgagtagc 15120 attttgtcga ttcgagatta attctgataa cgaatctaaa atattgaaat cttgaaaggc 15180 tttaataccg taacctttaa ccaacccagc caggccataa gcagcacctt tttggtcagc 15240 aagtgatgtg gagttcataa gcttgttact caataattcg taatactcct ttgatttacc 15300 taatgatttt ttaaccaaag gaggtaagca aactgcaaca gcaagctgaa cactctcgct 15360 gggtgtagag agtacactta ataagctatc cataacaaca gctagacgag gatcatttga 15420 aggtaaatgc tgtgctaccg tgccaaataa tacgacagta gcttcccgta aacgatcatt 15480 agcatcagta ggcaaggaat caacattcaa cttttgttca aaaagttcca ttagagcctc 15540 aacctggtgt gcacctgatt gaaaaattgc taattttcca gcctcaagca ttttcgatga 15600 cactttttgg gaagcatcag ttactggaat ttgtgcctcc gcttccgaag cagttaacaa 15660 gaactccaag aagggtaata gcaaattgga cgaaagatat ttggaaatgt gaaaaaagga 15720 tacggctact gattctctag ctatacgccc caaatcgcgt ccaatagttt ctttcttaat 15780 gattccatat tcatcatatt cgggagcaga aggtaaagca ttctcacgat atgttcgcat 15840 taattccttc ggtataaatt gaccaagctc ttcaaactcg tcaagcaaat caattaaaga 15900 tttaccaatg atctgctgaa gatagtccga atcttgagta aaaaatattt gaagttcaaa 15960 aaatgaagtt tcggtagcat caagtccatt ttgggtcgat atttgatgag ctatagatgc 16020 atttgtttca ttatcatcat acaattccag aaagatttcc ttaataaatt caaaacgtga 16080 taaatcaaaa gcctgtaaag cttgcaaaac agctgatcgg atactacttt ccgggtgaaa 16140 aagattactt aataataaat taagttcctc atcggtatat gtcgagtgta acccttcaca 16200 aagagaaagt aaagagtttt tattttcctg atactgcgta ggtgcaatct caagtaagtg 16260 cagcaatgat tttattagct ttgaacgcat tctccttagt gaagctgagt aaagtgcttg 16320 aaactccaaa atttctgtaa ccaaaagttg taattcggct tcatcttctt catcagaatt 16380 ggtgatatta aaggtcaagt cataaagtaa tggaaatatg catgcaaaca tttgtggctc 16440 aaaatagttt tgctcaatgg caaagcgaag tttgtaaagt atggattttg ttaattcctt 16500 aatattttca gaagaattta cactaaatgt atgggcaagg atagaggcga gactcgatga 16560 ataagatcta tcacctaatc gttcagaaaa tccagaagct ttcaaagtaa gcagaaaagt 16620 atcataggcc aagtttttaa gaaatggctc actatatttc agaacgttgt ggaaaagtaa 16680 gacatcaata gcatcttcaa cccatagggc aggtgcgagt tgcacagcct cacctaagct 16740 ccgaataatg cctaatcccc tttctaatga aagtgcaatc aagttgactc gactacgaat 16800 tttagcttca gcatcgagtt gtgcatcaac aagagcttgt tgatccttac tcaacttcgc 16860 aggcttttta gcagactgtt tcgccctcac ttcagcttcc catctcttag tctcataatc 16920 cttggtattc ttatcaagct tctttgaaga ttttttttct aaaacgttat cccacaatac 16980 accctcaggg gtcttccaaa tttctaaatc cgtacttgat acagaagaaa tgttaaggtg 17040 caacaattga ttacggaaaa catttacgaa caaaggtatt gattcttcag gagcgacaaa 17100 aacaatcatg gaaatagacg caatagctgc tgtctcttta gagtccttga tagcagaaga 17160 aagtaacaac tctatttctt cgatgatact gtgtatgcgt tcagaaacaa gagtagcggg 17220 atcacgttta gacacttgac agaagcgaat ccaatcaaac ttatccttaa atgcaaagga 17280 gaggaagagg agttcaacca aatatttatc gaagtcaaca agttcctggt ttgaaaagtt 17340 agaagtatca gcggacatcg atgaaaggat taaggattga aataatgagg aaatctcatc 17400 gtatttggct gagtcaaact ttcctacgct cttggacttc tcgaaatcag catgataatt 17460 ccatagttgt gagcaaattg acatacgaag atggggacgg tatagtattg ccgatttaag 17520 aatctttagc gcacgattag aattttcacg gctagcaaaa gaaaaaacgc cgatgaccga 17580 ttgaaaccaa cgttcaacaa aattggaaaa taacaaatta tcagaaactt ttgcaaaatc 17640 acagaggccc tgaaaatacc aaagtttcga ctgatcatca ttaagcttat tggtaatttt 17700 gctggagaaa atgaaaacat cattattttt gggagttgac agttttacta aaatgtcctg 17760 caattcaaga gtatgggata ttctctcact attccaaaca gacaacttat taacaccgaa 17820 acttaaataa attataggtg ctaagtatgt accattttga gtagcaccag atacagacat 17880 tagagccttt tccgtaagaa tagacaaatt atttaaaaag aaattgataa attctatttg 17940 aacatcatca gatgcaggaa gatcccatgc cattgtagct aaagatgtga gccaaaacat 18000 cgactcatga gcgacaggtc tctgtaggct tttagagaga aaatcgtaaa ttttgtctcc 18060 gggattacga ccattcatta acaaaaattt caacgtttta acaatcaatg acgcaagcga 18120 attaaaatca ctctcttttg ctttagtaaa aagaggtaat aattcattca acagcattga 18180 agcatcgata tgttttagag aaagactcga gagtgcatca acaaaaagaa cacgctgatc 18240 ggaagccgta acctttccgg ttctaagaga ggtaatcagt tcagacgcaa cgcgtgaaag 18300 tgattcatta tcactcgcat tagctgataa atccttaaac gtttgaaagc agtttcttct 18360 aacctctgcg tttgagcttt tcagtccgtt cacaaacgag gtaagtacag acgagagaat 18420 caaagaagaa gcatccacct ttgaatccgc gaaaccatga gccagagaag aaagtatacc 18480 tgaaaagata atttctggag agcgaagtaa agctttttca atggaaggaa gtaggtatag 18540 cttcaattga tctactgaaa gaagcaaacc aagactgtag caaaattcat gatacaagta 18600 tttctcaagt gcaggttttg ccattaaaac attttgggcc attatttttg aaaagagctc 18660 agcctgctga gaaatttcat tgcgaggatt gggagattgg tgaaaatagt agcatgtgct 18720 aataataaca ccatacaaag gtagagattt gggtggaaga atagcattct cggtttctgt 18780 caacagaaaa ctaaccaact tcttcaagga gtccattttt ttgcaaaata aagaacgata 18840 gcatctccta gtagacttta tggcactgtc agcaacactg ggttttccat cgcgtagagc 18900 atatgataaa aaactgcttt gtagtggaag cagttctaaa atccaatact gtagctcttt 18960 ctctggaagg ttgggaatca ttgaattaac ccagttaaga caatcaaatg atacagagac 19020 agtactcctg aagcgatcca atcttccagc gatggtggtc agccgacgaa ctaagaaagg 19080 aagcactatt gaaggtaatc tactgaccaa atgatttatt gttatttcga tttgttttcg 19140 agcatctcta gaaagatttc gtggtaaagt ttcaaaaata tcttccaagg cagcaatagc 19200 tgattcttcg tcaatatctg aaatgaaaag ttagaacaaa aagaacttca ccagttttca 19260 taaaattagt agtctagaag tctaaattac cttgagtacg acaaatatgc tgaaggatat 19320 ctatcataat cttcttcgat cccaaaaatg cgagcgaagt atctttactt agcaacatgg 19380 cataaagcat ccgatcttta tgaccatgtg cttctatccc aggttcttcg accgacatga 19440 ccgatatcgg agaaagaaat gttggttatg gacaggttcg cagagggtac attagcgtca 19500 agcaattttc gattacctaa cgaactcgag tttaccgaac caaattaata agttaatagt 19560 aatattctta aagataggta tttttgcgca aaattaaaga gtataaaaga aatctaaacg 19620 gctatatacc tgataatttc ataagagaat ttattttttt taaatttttt ttggctaata 19680 tcgtttatat ttatcaatac ttttagaatt cacagacaac tgcttcctaa attaattgct 19740 ttattttatc agcgatttaa atgcacctat cgtattttac gcgattttgg gacacatatt 19800 ctacagggtc tgttgcaatt atccatataa aaatttgtct atgtaactag tcttagtttc 19860 ttctttcttt ttgatgtgta acaaaaccaa ttatttgcta aacagtcatt ttataaagag 19920 ttcgttcaag taccagcaag ttaggattaa ttttaatatt atagatcctt tttttttttt 19980 tttaaattta aaaataatat ttaatatcag ttcgaattta attatatttc ccataaaaaa 20040 aaaaaaaaaa aaaatacaca tttaataacg catattacat gtaaatatta gttccctagt 20100 ttttgctagg ctgcagtcaa tattctatat tgtacaagca ttaagggtaa attaagaaaa 20160 aatcaaagta caaatgttta atgaattaaa tcttctgaat cgaataacaa aaatctaata 20220 tacttgctat gaaactctcg gttgtgccaa gcgttttaca ctcaccagta acagcttttt 20280 ctcttctttg atctattccc ttttcattgt gggaagtgtg taaagacaac ttgccgtcag 20340 ctacagcatc tataactgct ttgaggatac agtaaactac gatgactatt taacaaaatc 20400 tttttttaaa ataaagccat actgaaggat aatcggtata acaatgctta acattattta 20460 ccaattcagt ggaattacag aacaaagaga tgcacttttt gttcaattga gttatgtcaa 20520 ccacaagcac atacattggg aacgacggca tcgtaatgga taagattaag gacattaaac 20580 ttaagtaatg tgtaatgtag tgagatatcg atgacagtta atgttaacga cagcatagcg 20640 attagtccta atgcgttgct cttactttcc ttatttttta tttttcagta attaataaat 20700 tatcttgagg cttccgttcc ttttgagcag aataaatcaa tgaataaaaa gttttataga 20760 gaagttaaga caattatttt ttaataataa gtattgctaa actgatagat atgggctgca 20820 cattaacagt aaactttcca attctactag aaagctaaca agccaccatt cagccaaaga 20880 ctctttctaa aaaatttgat tatatctata gagtattaac agtataactt caaatcgtaa 20940 acaatacaag cactagccaa gggggtaata gcgtatctta acgtcctgag cacattgcac 21000 gctaacactt gtagtgccct aaacacaaat attttgcaga ggcgaatctg ctaaaagcca 21060 ataattcggt tctttgacaa acagccaaac attaaccata acttttttaa agatgtcttc 21120 gtcttttaaa aatgcaggtc aaaggaaaaa tcatcgagaa agagctcagc cttttgaaag 21180 acgaaaatgg ggtttgctag agaaacgaaa ggattatgcg cagcgtgctc aggattataa 21240 gacaaagcaa aagaagttaa aacgtcttcg tgaaaaagcc cttgaaagaa accctgatga 21300 gttttatcat gaaatgacac acaaaaagac caaaaatgga gtaccccttg aacagcgcga 21360 ggattcaacc atcgatatgg acacaatcaa aattttgaaa actcaagaca ttggctggat 21420 tcggcatcat cgcaatgttg aacgtgctaa aattgatcat ttggaacaac aaatgcatac 21480 tgtgggagct catcggaata aaaatgaatc caggaagcac accatcttcg tagacaatgt 21540 taaagaggca aaaagtttta acccagctga atttttccaa actacagatg atctggttgg 21600 tcgaaccgaa aatcgtgtaa agaaagatca aattgaaaac aatgaactga caaaccagcc 21660 tttttctgga aaattgcact caaaattaaa agaaaaggcg gcgaccgagc ttcttttgcg 21720 ccagaaacgc gacaaaaaat tggcggctgc tgaagaacgt gtcgagcttg atagactttt 21780 acagggaaaa ggaggccgtc agaaaaagaa ggtcgtaaac ggaaaaccgg tatacaagtg 21840 gaggaatgag agaaaacgat aatttcctta aattgctcct aacataattg aggaactgtt 21900 ttcagtttgt tgtgtttgtg atttactggt tgttatttcg tttctttcat ttagttgtac 21960 cttttttgtt atttatcatt ttctctattt agtatgaatg tacttaggtt ttggaatttt 22020 taacgaatgg attgcttatt tatgaataat ttggtttaat catctgtcta attctaagca 22080 aatatccatc tatttctcat attgagcttc atagtgttgt gagtcattca atattaccga 22140 attattttat cggtgagtat taagagtttg tcttaggttg taattcccaa actttaaaag 22200 tgtatggaat ggtttaattc aatgccttgt agtgtgataa attgtttcct ttctttttgt 22260 aattgcagaa gctagaatta tagttgttat tttattctaa tactctctaa agaaaatgta 22320 aagtacgaaa cgtaccaaaa aattcaagct atatcaaaaa gtgaatatct atagcacagg 22380 atataagctg aataacaatg aagacaatgc aaaaattttt accttaataa ttatacaatt 22440 cctagaaagt cttccataga atgaagaaat ttagagcaag caatacttgc actcagaggg 22500 tagtcactaa tactgatttt ttcgtcaacc caaccatccg aaaaatcgtc cggaccatga 22560 gccatagcac caattgcaat acaaaccgat tggttgggct gtaaagtctc aagatacttg 22620 cgaggaggaa cagtaggagc atcaaaagat aatgttgcct ttcgacagtt cggaggaagg 22680 tagtctgtaa ctggattttt gatcaccttt agaagctttt cattgccatt cacactacga 22740 atagagagct tgtgaagaag ctgcaccatc aaaccggaaa aacgtttgaa agttctagga 22800 atacgaacag agggattcac ttcaatcaaa actttcttag ctgtgtgaat gtacacttga 22860 agacgacctg ccttattcag tggagaatcc aaaagagtca ataagcattg atgagtaata 22920 tcaggacgcg cttgagcaat gttacggttt aactttttta aaataccttg atgatcatcg 22980 caatttagaa gttgatattt tgcatcctta gccttgccaa ctttataaat ttccaaacat 23040 gcttggtcca atacgacaat caaacgctgt gttgtagtat catgagaacc aattgacctc 23100 gctggtattg gcgccatatg ggtagtaaca cgatgaaccg accctgcagg aagtggacga 23160 gctttgacgg ttttggaaga agcaccattg ggatcctcct tttcttcatc tgactttact 23220 acattatcta tttctaaagc ctcaacaccc aactctcgat cgatagactc tggctttttc 23280 gaaagagctt caacagaagc ttgattctca cgaagtcgtt gtaattcttc atcttcaata 23340 gaacctactg caccattact ctgctccttt tcatcttgca tcaattcact agcagtttca 23400 cctgacgtta ttgtttcact cgattgactt ctctttatga atttgggttg attggttttc 23460 tcagaaacct ctaaagagcc tctagacttc cttttggaat aagtaggcat gaatgatgaa 23520 aaagctagtc taccagatat tgggtttcga caaaaaataa tggcttgaga aatttgcttt 23580 tggtggtagc tacaaataac tatcagatct aacctacctt gcttaaacaa gataacgcat 23640 atttacgaac ttacgatccg cttaaaccaa caagtgtaaa accaaacata tcactcgcgc 23700 attgagctga acaaaacaat gacttatcta aatcaacaaa aaaattataa aaaatctaca 23760 cacgccgaaa atttgttttc aatgaattct atattaacta aaaaaatgca ggtaatataa 23820 gtccatcttc agcaaaaaaa aaaaaaataa aaataaaaat aaaaaaaaaa cggaaaagaa 23880 gtaaaggaag tggattaaaa ggaatgtgta aacaggtatc gtcaacacac agaaaaaccg 23940 tgccttctaa tactgttgca catatcaggt ggataaatac acaaacgcga cacatcagtg 24000 acggaaatat gtgtttatat tagaaaaact aaatcaccac ttaatgcaac attatttgta 24060 aacaatgaag gaaagagata aatttaaagt tttaaaaaga aatgattcca aaactattta 24120 caaataagag caataaatgt tgccgtaatt cagtctttac gtaaaaacga tttgcgagtg 24180 aaagatatta taatcaacga taagttgact atcttgacta gcaatgaaag ctcaaaaacc 24240 gagggcttga aaattgcaaa cattcaaaaa aaaaaaagca taaagcacat tgcatgtact 24300 ccttgagcgt agaagatagg ttacaacatt cgccaaaaaa ggtgaccaca taaatatcac 24360 ttatattagc aaacatcatg tatatcatgg acgaaagttt aaaaggttgg caaccaaagc 24420 caagttcatg agaggaaaag aagattataa ctataatcct cgacacagga aaataagatg 24480 tactgtcatc gcaaagcaat aggcaacacg tcagtaataa ttaggaaaat taaaagaaaa 24540 aaacacaaga gaaaaaaatg tacgagaccg gtgaaacaag tttcaaacaa atctcgataa 24600 aagcacaacg agattattaa tagcataata aaaactagcc agaataaaat taatgcaata 24660 tgcagatcat aacacccaac gctcataaaa aaggtaacaa atgcccattc taagcataca 24720 aatcgaaaag taaacgaggc acattttcga taaatagtca ttgacgaaca tttccatatt 24780 ataaatgaat tgctcgctca attaactaac aaggaataag atgaagttaa ggaaatctag 24840 tcaataaaaa tcaagatttc aaatccaaga aatccattaa aaacgttggc atttctttta 24900 actataagcc gttagaaaag gaattcagta gcttttgtat gaaatcctct aaaaaccaaa 24960 agcgaaggaa acaaaattaa cccatataga gagctaaatt ctataatcca aaaaaacaga 25020 aagacagagg tacatagggt gatagtaaga aagtcataat actagcaaaa atactagact 25080 atgataaatt ctcttggcca atgttcaaat aaatagtgct acaacgaaca cgtgtagata 25140 aacgcggaga cgaaagaagg tgaaacaaaa aagtggaata gttagaacag aacacgaggc 25200 ttaaaaaggt gatatgtcct tagacataaa taagcatcca atgaaactat gcacttcctt 25260 gacgcagcat acggaacaag cgctgttcac gatcgcgatg aaacaataag tctagggcag 25320 aagtagaatg acaatgaatg ccgttattag gggaattcaa agtaggggta atgttaccag 25380 tgggatggcc ggcagcattg aagtgattaa aagaaggagt ggaagctgaa tagttagtat 25440 gaggagaatt gtgtccactg taaaatccat tcgtctgttg aatactctgc aatgagggat 25500 cgttacgaga catcggacaa aaattatgac ccatggcaac ttcggatggg gttgaaggaa 25560 cagaggaaga ttgatgaaac tggaaaggca tgtttgagtt cacactacca gtaggaggtt 25620 gccattcagc cttttcggaa acgggagagt gtaagaacgt agggatggga agattagaag 25680 cggccggaga atgagtaaat gtaggaccgg cgtaaagaat ggaattagta tcggaagagg 25740 aattcgaaga aaaagatcga tcagcaccgg aagaattgga aacgtaagaa gatacagact 25800 tcaaatgaga atcaacttct ccgacggcaa ccttatcaat tcctaagcca gcaggagccg 25860 aagcaacacc agaaggaagg tgggaattag aattgccacc tgagatacga gagccagcat 25920 acgaactgtg accagattta gagcgtcgat tcccgcgtac tttatcgcca tttcgcttac 25980 cattgctttc accaatgtta gaagtagcaa aagtactctt gggtttcaca aagttaggta 26040 tctggagatt accatctcgt tggggcataa tcgacattcc atctaaactg aactcgacat 26100 cgctggaagc aaccattgct ccgcccggtt tagaattaat tttcttctta ttacgttgaa 26160 atctacgtcc aatgtctttt tgcatttttt actatagtca aaattcgagt aatccctaat 26220 gatcatggat tctgtattct tagtgattga tgttggttaa ggataacttc gggggcaaca 26280 ctcttaccca atatacgtta tttgggctga ggtgacacaa agcaatgagc tgcgctatgc 26340 ctccttatag agctttcttc ccttaaccat tatttgccac ccactttaac tggcaaaaag 26400 aaagaaggaa aacaaagatt cggcacaaag atagagaaat aagaaattgc tttaccttcg 26460 tttagtgaag tcttttatta aatttgaaaa ggtgtgtttg aacagtggaa ttcaagcaat 26520 ttcctaagta tattatagct cattgctgta atattataaa tttgtatggg attgcaatta 26580 cgttcacgaa tcagcaactt atgccaggtt tcctttttaa tgtagataag gattcatgta 26640 attaactagc ttatatcagc tttataccat ttttgatcag tttgaattat tcaccatgga 26700 caattgggag gaccctaact tcgaattgcg aaatcttcgt gtcatagact tgaaaaagat 26760 ccttcatgaa tcgggagtgt cattccctgt gaatgccaga aaaatagagt atattaggat 26820 ggtggataga atacggaaaa acaaattaag ctctggtcca caacatttat tgtctcatct 26880 tcaaaaagag gaaaactcta acacctcaaa agcgtctagc tccgaggatg aaatagctcc 26940 taaatacctt tatccctcct ctccttccaa aagcacgaaa aagccacaca acgaaacaga 27000 accgcttctg tctccacaat tcattgacaa acctagcaac attgaaaccc cggttaaaat 27060 agagtctccg cacgtctctc aaaataatac ctttcagtcc tattctgaat tgagccctaa 27120 tgtggaaaca tcgctgacta tgaaaactcc gccagcccac gcgtctacac caaaatttcg 27180 ctcgcataaa tctcataggg tagctgttcc tatgtcattt atggatagct ctgctttaca 27240 tacttcgcca gcattttcgg agaggttaaa gctgctttca tcttcaaaca atttttctcc 27300 acaattgagg tctcccaaaa tatcacatcg tctacaaact tcagccactt ctagtcctct 27360 tcaacataaa cgacccttta ctaatgttcc tgagcgagtc tctcgagata tcgagtttgc 27420 tcctcttgac agtgcaaggc cctctgaatc ttcatcgcct tattctgaag tagactctgc 27480 tgaggaagat gacgagcttt ttcaaaatta cgttttgcag cagactcgaa aagaaagcaa 27540 actttggtcg tttattaaaa aagtatttca cgacattaag tacgccaatt atcgtcttct 27600 tcacaatttg cgcgcctttc ctggaatcag cgcgatatct tcttcttatt tagtgcatat 27660 ttttatgatt ttattaggag tggtggcagc aatttttctg gctttattac gggagaaaat 27720 gtttacagca ggattctgtg attcgggtgc cagtggaagt tctgcttcaa ttcttggaat 27780 aagttttcca tcattgtgta gaacttgccc tccgaatgca atatgtccct ctccaaatta 27840 cgttgaatgc aagcccggat atgtcctcta cgaaccatgg tattcaagtt taggattttg 27900 gccctccaag tattgcgtta gtgatacttc tagagaagaa agtgttaata tttttcgtga 27960 agaatgttta agtgtattaa gatcctggaa tgcaattttg cattgtagca ataactcgtc 28020 agatttgctg gaacgaaata tgtcgtacaa tgcgcaccct tatgtcgccg ataatcttaa 28080 tatatcatct gatcatatct ccttcccatc aaaaccattt gcgttaggat tattacatga 28140 tacgcttctt gaaagaaaat ctccaaccct tggccttgaa atgtttgagg acttatttaa 28200 agcttctttg gcagtacttt ctgaaacgaa tgaagttgtc atggattcaa aattaatttg 28260 ctacgatagc tgggcaggta ttcctttgcg gtgtcgttta aaacagcaac tgataaaatt 28320 tgtttggagg aacaaagttt ttttatttgg aatccttgcg ttgtcaggag ttatttttaa 28380 gctcatcaat ttttttcgta ctcgcagtat cgtagcaaag tatctaccat cggcttctcg 28440 attctgtgta gaatctttga agagacagaa agcaaattat caaatgtctc gatctcaaga 28500 acccgttata ccactaatcg aaatgcatga tatactcttt catggaaatg gcccattgga 28560 acaaattcat atgacgaaag caactgctcg aactctttgg gaagcaatag tcgaacgtgt 28620 tgaacaagtt ggcagtgtaa gaactcgtga atcagaagta gacggcgaat ggacccgtgt 28680 atgggagtgg gtcggcacaa atactttgga tttccaaacc gatcgttcat ttattaatac 28740 aacttcccct ttacgtgaat aatgattctc gactgtattt ctagctttgt atttatgaca 28800 tttttcatag ctaatacaaa agtaagttaa taatatattt atctgaatgc ttatacatat 28860 taaaaatgaa acataaaatt ggtataatga ggacttgttt gcaaggttga tgaaatttaa 28920 ctgtatttct tatattaatg tgattcttag ttataccaaa taaattattt taaaataaaa 28980 accaaaacca gtaccatttt tgattgaata tgggcatgtc tagagtaaga aattagcgga 29040 gaaaaaatag gacatgtcac atagaaaggg tatttaaaaa aaaataaagg aattcaaaag 29100 ggagattcac ccaacattac ggttgaagat tcgtagtctg tgtcttcttc ttcctcgtca 29160 tcatccaaac ctggaatttg ttgccattcg ttataaaatg gttgaacaat tatagaagac 29220 ttcgtaagcc ggtaaggatc aaagggaaaa taggcatcca tagtgtcgaa cccttctcta 29280 aaaattcctt ttctgttttg ctcaataatg gaatagacgt acataaaatt gagatgattt 29340 gcaacctttg caaattgaag tacaatattg ggggaacagt atctcaatgg attaagccga 29400 gaaagaacgg accgatgaag tatctctaag cccggtatcc attcgttagg tcttggctcc 29460 atggattcag actcatcaga gacacaaagt tcacgccaac gaaagcaaaa tatgtaaaaa 29520 atactttgat taattgcgta aaaaaccgag tgtttagata gtaaatcatc ggacagctcg 29580 ttttcacatt gatctaagta agcttcaacc caacgagtca tcatattaac gatgatctga 29640 attgtatttt tttctaaagc tttggctcta gcaacgtaag acccaatata cattgcacca 29700 cttaatctta aagtataagg ttgtgatggg tcaagacaaa cttccgtaag cactccaagg 29760 aaaatatcag taaactcggg atccaactga gaagcccaaa atatcaaaaa ttgagtatat 29820 cgacaacgga acgttttaag gaccgtgttc acaaatgatt taatcaaact attataaacc 29880 aagtaacgat ctctactagt agattttaaa ttggaatcta aataagaaaa taaagtatac 29940 aatagctgat ccagttgctg catcaattga cgagtgtctg ttaatgaggg aggagtcaat 30000 attgtgctag atgtcatttc acttgaaata gcagtatgcc gttcatataa cgttgaagct 30060 gtaataactt cagaatcggc attgctagtt ccatcatcat ctgttaccac ttcatcctcc 30120 tcctcatcat catcatcaac ctctacttgt atttccacat caatttggat aattttatca 30180 attattgcat gcaatacagg acctttaatt gatggtacat attcacatat acttaaaacg 30240 ttcgaaatat aagtcatctg tgctaaaagg ctctcgtcct tgtacggaaa ctcctcaagt 30300 atgctactat acaagaagga atgcgcacgg ggaacaagtt ccaacacata ttttaaagcc 30360 atatgagcat gttcataatg gattgctaaa ctatcaggcc gatacaacat atgctgaatc 30420 agcatagtca taactagcgg caagtaatta gattgtgcag atatgagatt tcctaaaaat 30480 cgagtatagc atctcacaaa ggactcatct ctgctcaccc aaacagaatc tagtacgctc 30540 ataactaaag aagaattaga gctatccaat ctggaaacat tgcacgtcaa agccgacaat 30600 aagttttgaa gttgcagaga ggaaggtgca tctttagtat cactttttgc agcaaactgt 30660 cttctaagat cttcataacc ggcaaaattt ccttctgctt tgtcgtccaa agctttattg 30720 acgaaagcac gtaacatttg ttgcattaat cgtccatcat ttttggaaac tgaagaggca 30780 aaacttttgg aacctacagt acgatcggga acatttgtag aagatgccat tgtcccgttg 30840 ttaacacatt tattaatata ttgaggattc gtagaggaaa tgatggaagg cattgtaaag 30900 acgagataaa cacttgcact aatcacagat aaaggaatgg atgcaaacaa aaaaataata 30960 agaataacac tagcggataa attcacgtat ggttattcta aactttgtaa tagttagttt 31020 caaagttaaa ccaaaactta agagtaaagt aaatgtggaa ataaactgtt tcaagtcaag 31080 ttgacccaat tgcttaaaaa accaaacatt gctatatctc tcttattaat aaaacatttc 31140 cttacaattt ccaaaaacta agccgttaat ttgcttcgaa aagctaaatt tttagaaatt 31200 tacaggactt cccacgaatg aattttacac cccaaaaact tttcggtgtc tcaaatgagt 31260 cagataaaat aatcaaaata aatttgtaag ataaaacaaa tttaaattat aagagtgatc 31320 attaattcat tcaacgtaaa agcaaaccat gtgtggcggt tggcagaaac tatgctaaca 31380 gtttgtaaag aaaatttgag tatatactga aatgcagcgc attgcgctct ttgctaaaca 31440 atgcaatata gataccgatt tctaatgtat gctaagttaa aaactatgta gataccaaat 31500 taagtgtaat attaaacaaa gaaaagtagg gatcttccaa ataaaaccgg atcgaaaatc 31560 aattaaacag aataaataaa gcgtgataat tgttttcttc aaataccaga gttccttcga 31620 ttactagtag aacgtctgcg gcgctctctc aaagatgcat ttaaatcttt gtatgcctgt 31680 ttgtacatta aatacatttt tttcgataat tcgccaatat ccttgttact tcttcctgaa 31740 atataatagt agttttcatc ctggtatgta aaagcgacac gacgatatgg accagaaacg 31800 tatttatcct tagggattat agtggcagca tagggataag tagagttatc cggtgttggg 31860 tttaaaaagg aatttgagcg ctccatccat gcaggaatag tggtagtctt catgttgatg 31920 ttaggctctg ccaaataaat tgcagccgca ccctggctaa tggcacctaa cactttgatc 31980 tttctgttat ccttaacctc ttcatccggt tgaattgtac gacatgaatg gatgtaagga 32040 accaggctgg catgtaaaag tgggtcttct agcatctcac gcacgaatgg atttctccct 32100 ccagttatga aaacagcact aaaattatca aacgtaaaac catttgatcg atagcatttt 32160 ggattgttga actcattcag agtacagaga acgctatata tgtctaagat ttccttagaa 32220 gcaccgagta catgactctt ccagccggtc atataagaat cattaggttt cgggggtctt 32280 ggaggaaata tggattcggc gattacgaat tcaactacaa acccgcgatc tgtaaaatac 32340 ctccaaggta gacatacttg ctccaacatg aaccccttat cagctaaaac gatagctaaa 32400 tgaggcgaca atttggcatc cttaccaaat accggagcat tcactgaaat gaggtcgtgc 32460 ttgggatgaa ttgcagcatt atagttgtca aatgagttca tttttgaaac ctgaaaggaa 32520 aatgccatcg tgcttaaaaa ccagttaatc ctcctttttt aaaaaacaat ttaaaattaa 32580 tagcactgta gattgtatat tagttatatg tcttacacaa gaaacctgga aaagtgggta 32640 aagggatgat tgaccccctt aatatattac cttatgttta ggtcaaccaa aatgacacga 32700 ttctacaggg tttcgatttt ttacaaaaat ttagcggtat tcagaacgcc tttcgcttct 32760 tccaaagctt cgttcaatgg gtagtggttt gacttgctga tcatatataa tttatgtatt 32820 tgattattta caaatcacct aattggtaga aatacttttt taacaatttg tacaaaagca 32880 tagatctttt tgttgcttat aactgtagaa tacaatgtaa taggttttca tcaattatgc 32940 tggcctgatc aaatatatga aattaatcga atctgtaaaa ggacttagtt ttacaaacta 33000 acttagcatt caggacattt catcaattca ccaacattaa tttacatggg caaggaaact 33060 gttgcttttt ctgtactttt aattcctact ttaaccctct atgaactagt atgcggctca 33120 aagtctcctg caccgaattt ccaattcaac aatgggttga gacttctagt cttgaattag 33180 ttgactctgt taattgtgtg gcagatttat gccatgccat atggatgttt aatggaggat 33240 gtgcggattg gaggcttcaa atacttaaag aaggatttac agttccgatg acgggaatta 33300 tctcacaata tcttaaaact gacgaccaca ttaaaattgt gaaggaaatt tatcctccga 33360 atttacctgt tcttccgttc agagtgtata caacgcagaa tacctccgtt gaatctgagc 33420 tagttgaatg ggaagatgta gaaatggagg cttagtgctt tgcttgctat tctctgattt 33480 atttgattaa aaaattatat tataaagcta tctgcaatgg taaatcacat gaacaacgaa 33540 ttgaagtttg caatttaacg atcgcttatc tgtcccttga acctacgaca atttctaaga 33600 agtttaggat gacattgcac tgttttcatc attataaact taatggacca gcagtattat 33660 gcttaacgtt tgcactgccg ctgctttgac actaaacttt tatgctaaga tatataacac 33720 ctatgaaaag ttcagtctat gaaagaatat agaatatata ttataaattc tgtatacaac 33780 aacaaagctt gaaaatttta ctttttactt acacaagcga caataaactt ccacgagagg 33840 aggttaaact tggaaattag atgtattctt ttctacgaaa tttatccata cgcgctaagc 33900 aatcactact ccaaagcaag tatacaatga agtacttatc gatgatacaa ttgtagtcag 33960 acaacttaaa ttattgaaag ctatgaaatc cgactcgaaa ccgatacgaa cgcaaaacgt 34020 gaaattttat tgcttacaag ccctcgccgg tagcaacagg gaactcgaat gtaacatttt 34080 tgccagtgag cttgtggtag acactagaaa aggaacccaa cttataatca acagtgttag 34140 catctctgtt gtcaaggaaa accttgatag tcttgcgacc gtcagtagct tgacgagtac 34200 gcttgccaat gatctcagtg gggaaaacaa tgtcttcaag aatagcgttg tgaacagcag 34260 tcaaggtacg agaacgagga cgcttttgag taacacgaga cttacggcca ggcttgggca 34320 agatacggcg ttgagcgatg aaaattacat gacggtcagc aaacttcttc tcgagctcac 34380 gggtcaaacg agcttggcat ttgtggaaag ccttaagaag gggttggggc acaaaaacaa 34440 cgattgcctt ctttccacct ccaacttcaa cttcgcgagc agaagtaatt tggagagggc 34500 ggagctcctt ggccatgtcc ttagaagaac tctctaaatc atagagacat tgagcaacaa 34560 ggaggtcggt ttcagtgggc tgggagctcg aacgcttgac aatcttgttg agagcagaca 34620 ttgctgttgt gtagaaaaga aattgtttcg acctctccat atttcacttt gtgactgctc 34680 ttccaaaatg ttgccggggt aacatgtaat ttaacttggg tcttctactc tttgcttgac 34740 ctgcgtacat cgttaaaatg ccttaattgc attctgtagt gaagatgcct acaatcgaat 34800 ttcaaagcta agtaggaagt taatcaaatg gaattatgta tgccatttga acgataatta 34860 taacaatttt ggtcgaacgc aacgatcgta gttttttggg tcatgtttgt ttaccataag 34920 agcagtcaca tatttacgaa acattggatt tttttcatat tatactagag taaatgatga 34980 gaaatttatg tttacaagct aagtatgaag gatttatctt caatattttg ttaaacatgt 35040 aaatgccgat tgatgattta tatgtagcaa acgtatgaaa taatattttg ccagaattgt 35100 tatgttctta gaagactttt ccttatttta aattattgtt gttaataaca aagtaagcat 35160 aattataatt tataattaca atctaactaa atgcaaaact gctaaaactc ttactagtaa 35220 ttacatacat cggtttatga atttagatgt aaaaactaat caaattattt tacgtttcta 35280 agattatacc aagtccaaat tttttgtcta tttcatttat ttgtaactgt ttttctccga 35340 tttattgttt aggcatcaca tagtgcatct ttcaaattct gcctttaaaa atgttgttta 35400 attgattaat taaatcaggt ttatcccaat cttttctgct tttaatttca acatccagcc 35460 tacttcttta gtaaataaaa aaaaaactaa ttgagagata gttattttaa tgtttgcaac 35520 gaatattccg gaatacatgt aaattttcag ttataatacc cattaaagat ttgtttacat 35580 aacttctact tgtttaaaat cagaaataat ttatagaaaa tatgataaat aaaatcccaa 35640 gctaatttat ttgttcactt ggtgtcaata aaattcattg tgttttctgc agcgcttgta 35700 cgacgcgact ctatcatctc aataccacac aacatgtctg aatctcggca agagctctta 35760 gcttggatca accaagtacg ctttaatatc ttagttagat tgaaaaaatt atcagcttac 35820 tgacttattt taaaggttac aagccttggt ttgaccagga ttgaggattg tggaaaaggt 35880 tacgctatga tacagatttt tgactccata tatcaagaca taccactaaa aaaggtgaat 35940 tttgaatgca ataatgagta tcaatatata aacaattgga aagttcttca acaggtattc 36000 ttgaagaagg gtatcgataa agttgtagac cctgagagac tatcgcgttg taaaatgcaa 36060 gataatctgg agttcgttca atgggccaaa cgtttttggg atcaatatta tcctgggggc 36120 gattatgatg cgctggcacg ccgggggaat agaggacctg ctaacactcg tgttatgaat 36180 tcctctgcag gagcaactgg cccttctcgt cgccgtcagg tttcttctgg tagttctaca 36240 ccttcaatga ctaagtcatc agcaaacaac aataacgtgt cttcgactgc aaatactgcg 36300 gcagtgttaa gggcaaagca agcacaacaa caaatcacta gtcttgaaac acagttgtac 36360 gaagttaatg agacgatgtt tggtttggag agagaacgtg atttctattt taacaagctt 36420 cgagaaattg aaatacttgt acaaactcat ttgaccactt ctcctatgtc aatggaaaat 36480 atgttggagc gtattcaagc aatactttat tctactgagg atggttttga gttaccacct 36540 gatcaacccg cagatttaac taccgccctt acggaccatg atactaacaa cgtcgctgaa 36600 gaggctcaaa tgactgacct aaaagactca gaaactcaac gcgttccctc tgcaccagat 36660 ttcgtacatg ctaggctaca aagtttagag gttgatgacg atgagaatat cacgttttaa 36720 aaagtactaa gttaaagttt ttttttgttg caaattcttc atttttcact gtaacaacgt 36780 aaataaagga aaccgaaata tttattttta tagggagttc ttcttattcc ttattgttta 36840 tttaacctga tcgaatgttg cgtgcctcat gacctccaaa ttcatttaat ttcgttcttt 36900 ttccttaaca tatagcattc tgtatactac aaatgctaat tgtaataaac tttaatcctt 36960 agtgtttgag ccgtctaatt atcccaaata ggatattttt cttatttctt taaaaaagct 37020 tcaaggataa tttaaattta tcctgcttct acgtttcagt gattacgaac caaacttttt 37080 tataattaaa tgttgaaaag tatgaatgga tgtttcagaa ttttattcaa tgatgctgaa 37140 atatctactc gatttaaaaa aaatttgcat ccgattttaa aatcgccttt ttcatatatg 37200 agcaaaataa agagtaaaat atttactttc aatgatctga ttatgttaaa acgtttcaac 37260 tgcgtacgtc tcagcgatgt agaagtttaa ttacttatcc ttatcttata tatatatatt 37320 gttgacttta taaaccgtag gtgtttatgc ttgtcatttt tactagcaat agtaaagtat 37380 gtaaaatttt gaggtacctt tgttagttta ttttttttac tcgaactata tcaactttaa 37440 atagcaaatt tttaaatcaa gcttaaagtt atgcaattca gctacacgtc gttaataata 37500 aataaaactc tttcattcac aattctttaa atttgcaaag caaaaatctc aataatgaaa 37560 ttcaaagcac caagtttccc cccccccgcc ggggggtttg atcaatttgt cttatctgat 37620 c 37621 //