ID SPAC18B11 standard; DNA; FUN; 22847 BP. XX AC Z50728; XX SV Z50728.2 XX DT 03-AUG-1995 (Rel. 44, Created) DT 14-NOV-2000 (Rel. 65, Last updated, Version 6) XX DE S.pombe chromosome I cosmid c18B11. XX KW acetyltransferase; beta-transducin; EF-hand, calcium binding; rhp6; KW Trp-Asp repeats; Ubiquitin-conjugating enzyme. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-22847 RA Devlin K., Churcher C.M.; RT ; RL Unpublished. XX RN [2] RP 1-22847 RA Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (02-AUG-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; P23566; P23566. DR GOA; Q09707; Q09707. DR GOA; Q09708; Q09708. DR GOA; Q09709; Q09709. DR GOA; Q09710; Q09710. DR GOA; Q09711; Q09711. DR GOA; Q09712; Q09712. DR GOA; Q09714; Q09714. DR GOA; Q09715; Q09715. DR GOA; Q09716; Q09716. DR SWISS-PROT; P23566; UBC2_SCHPO. DR SWISS-PROT; Q09707; YA39_SCHPO. DR SWISS-PROT; Q09708; YA31_SCHPO. DR SWISS-PROT; Q09709; YA32_SCHPO. DR SWISS-PROT; Q09710; YA33_SCHPO. DR SWISS-PROT; Q09711; NCS1_SCHPO. DR SWISS-PROT; Q09712; YA35_SCHPO. DR SWISS-PROT; Q09713; YA36_SCHPO. DR SWISS-PROT; Q09714; YA38_SCHPO. DR SWISS-PROT; Q09715; TU11_SCHPO. DR SWISS-PROT; Q09716; YA3B_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/~yeastpub/svw/home.html) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites CC CDS are numbered using the following system eg SPAc5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c18B11 is overlapped at the 5' end by cosmid c1F5 CC nad at the 3' end by cosmid c12G12. XX FH Key Location/Qualifiers FH FT source 1..22847 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c18B11" FT /map="1L" FT misc_feature complement(1..881) FT /note="overlap with cosmid SPAC1F5, EM:Z68136 S.pombe FT chromosome 1" FT CDS complement(423..4307) FT /db_xref="GOA:Q09716" FT /db_xref="SWISS-PROT:Q09716" FT /label=SPAC18B11.11 FT /note="SPAC18B11.11, len:1294" FT /gene="SPAC18B11.11" FT /product="hypothetical 149.2 kd protein" FT /gene="SPAC1F5.01" FT /protein_id="CAA90595.1" FT /translation="MKALDIDTILTQISNQQSLDKRYKRIKRLINNEQFCKNVILQKLV FT DSTKDIIENKVHGNILAATISLWTHAAEKHKEMSSDDRALLFNELSKVPNSEYYPATVD FT ALIVITSQGERTESFSNDILKVLSEWLTDLFTIIDDMRAQSRKSFKGSAELRNYTRCFR FT QIILLLTNMFRVGFNLFDEMEVSSMLANCVWVSKSTTDEEDIALVFSLLNCIISYGRIS FT SAVLYSIVEVVCRAKFGLVASSQSAQQIVEKLLKTATKYEALNSLKRIMEETDEGSYIA FT IMGGIQIVSALFTDIPRSVYCTRGMLLGFLQRSLKNKSSRIALETTRSLYNALERRSFV FT EVLYADEWISLLDLLVEISSSLPKSLNYRPGTWQHIEPNIIESIASYQLQHLLLFNEIL FT KPDSNHFVLEKFHEFLKINFSYLTPTLSQKLFTVLDLRSQLPYSEGWLEDQTILLKSYF FT DTSFSLDFHVYLIGLFRKVLFACPVELRPEVYARMLCPLVKSLDKSSSEVIIDEVISLV FT CDLSWIYPSNVFHEVKDSLCFYAHNSSNGDLQLRSIQAIVSLTFYYVLLPEFKSVLYDG FT LVEISCDFKIRRTFRIPVLKLLLQLRINTNDYCFVNLSPAQLELISVYSTQWHNPFISE FT EAQRCRDNKVKDRDLSFSPVFQKFPLKVNTSATLSKDLMSLPINEWVKNVMYIVTHETD FT WKVVQYILINFTNQLRNTKMFTKTVEALQLLLNSLRDIINGKQSLNINFSDFFRIEDLL FT VSLSKILSVLMVYKDVLPPTAHEQFFQLLNRFAEKGDKTMESCIDTLITNCCAMQSFSI FT MHLPKFFSITMSSNLSERSLVNFLRLLHVVSDNWELNEGLEKETIQSICLFCLKVIRTK FT KEELDGHKKLVNPNTKVFCLYLVSFSYSIISNLFLGCETTERAQLASFLLKEFLNLKNG FT SHFEGYERVFYELLLRYTYSDERIESYPSDSRFHFNSSSKSWLYRGCVITINAEYETGD FT YQMILRRMSGTTIYRFWRNMRDRGAFEKSLMMEQSMVSSELKQKYLQEIAASHVFMETV FT LSPLDSPDEEPILIKPDARTEELIQSLDATHTKPVINIAVALQAGDVSDINTTVGWQLF FT YRLLESFGHEKKLDNGETIYVWQSKTIEMIFRYVSDPAEALESSLYSSLIIIGSDDLVG FT PDSLNWDSVDVPVIIKISLDSHLDALKMFDTLFHVKLEIITTGTDISHQSFWKLDQIIS FT TNSIAPLLHSYLADIGLYQMIFENFAYVHPWLLRQQYIDTLYTIHQVPTTQRESSALPS FT DKTFDFTLFL" FT CDS join(complement(7109..7232),complement(6957..7041), FT complement(5149..6784)) FT /db_xref="GOA:Q09715" FT /db_xref="SWISS-PROT:Q09715" FT /label=SPAC18B11.10 FT /note="SPAC18B11.10, len:614, SIMILARITY:Neurospora FT crassa., RCO1_NEUCR, transcriptional repressor rco-1., (604 FT aa), fasta scores: opt: 1424, E():0, (42.5% identity in 626 FT aa)" FT /gene="SPAC18B11.10" FT /product="WD repeat protein; related to tup1 glucose FT repression regulatory protein" FT /protein_id="CAA90594.1" FT /translation="MASVEDATKVQEMLDALKAEYNALAHHSFASKARGNDYESSMIQS FT QIQEIEAFRKTVDDMYEKQKSIRETYEKDINKLKRELEELGVEANTASYRNRGERSELA FT ASNNQVTHIDQEHPSQTKSTSQPPSNHLPAFQQIPPIHQSAYPQNNVAEVLMPPIPPSV FT EASSGQNFNQGIASQNPAISTSNLPSTTPLYIPPVNYGANQVSQQPNPQLPGVSNYYNP FT SATSKPAVNVQPPRIPTKATPSAEPSMTASANAGSISQAGPDGEYQGREQIAPVSDTEA FT ARKTTSQSWYVTYNPACKRVFNINLVHTLEHPSVVCCVKFSNNGKYLATGCNQAANVFD FT VQTGKKLFTLHEESPDPSRDLYVRTIAFSPDGKYLVTGTEDRQIKLWDLSTQKVRYVFS FT GHEQDIYSLDFSHNGRFIVSGSGDRTARLWDVETGQCILKLEIENGVTAIAISPNDQFI FT AVGSLDQIIRVWSVSGTLVERLEGHKESVYSIAFSPDSSILLSGSLDKTIKVWELQATR FT SVGLSAIKPEGICKATYTGHTDFVLSVAVSPDSRWGLSGSKDRSMQFWDLQTGQSYLTC FT QGHKNSVISVCFSPDGRQFASGSGDLRARIWSIDPASP" FT misc_feature complement(5170..5271) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 42.08" FT misc_feature complement(5296..5412) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 33.49" FT misc_feature complement(5455..5499) FT /note="PS00678 Beta-transducin family Trp-Asp repeats signa FT ture" FT misc_feature complement(5461..5574) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 53.72" FT misc_feature complement(5581..5667) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 29.02" FT misc_feature complement(5701..5745) FT /note="PS00678 Beta-transducin family Trp-Asp repeats signa FT ture" FT misc_feature complement(5704..5817) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 61.40" FT misc_feature complement(5827..5871) FT /note="PS00678 Beta-transducin family Trp-Asp repeats signa FT ture" FT misc_feature complement(5830..5910) FT /note="Match to PF00400 WD40, WD domain, G-beta repeat FT Score 30.97" FT misc_feature complement(6785..6797) FT /note="ctaacatttatag, splice branch and acceptor" FT misc_feature complement(6951..6956) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(7042..7063) FT /note="ctaacattctgttctattgcag, splice branch and acceptor" FT misc_feature complement(7103..7108) FT /note="gtacgt, splice donor sequence" FT misc_feature 8241..8350 FT /note="similar to a region internal to predicted protein FT sequence SPBC16H5.13 70% at the DNA level" FT CDS join(8682..8752,8855..9161,9237..9314,9373..9540) FT /db_xref="GOA:Q09707" FT /db_xref="SWISS-PROT:Q09707" FT /label=SPAC18B11.09c FT /note="SPAC18B11.09c, len:207, SIMILARITY:Saccharomyces cer FT evisiae, YJV8_YEAST, putative acetyltransferase, (196 aa), FT fasta scores: opt: 459, E():0, (40.7% identity in 189 aa ov FT erlap)" FT /gene="SPAC18B11.09c" FT /product="putative acetyltransferase" FT /protein_id="CAA90593.1" FT /translation="MTRTRVQKMIPKTIEYQKMISGQPYKAYDEELTQARCNAKKLMRR FT FNDTMGDLENVGPAELIKRRAELLAEVFVFDESSAPEIEPPMAFDYGFNVHFGKKFFAN FT YNCTFLDVAIITIGNNVMLGPNVQLCTATHPLDFKARNSGIEFGLPINIQDNVWIGMGV FT IVLPGVTIGEGSVIGAGAVVTKDIPPNTLAVGSPAKPIRKIENE" FT misc_feature 8753..8758 FT /note="gtaagg, splice donor sequence" FT misc_feature 8837..8854 FT /note="ctaattactaaataacag, splice branch and acceptor" FT misc_feature 9030..9068 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats)" FT misc_feature 9138..9242 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats)" FT misc_feature 9162..9167 FT /note="gtatgt, splice donor sequence" FT misc_feature 9219..9236 FT /note="ctaatggtgtctttccag, splice branch and acceptor" FT misc_feature 9315..9320 FT /note="gtatgc, splice donor sequence" FT misc_feature 9350..9372 FT /note="ctaacaaacaaaattttatcaag, splice branch and acceptor" FT misc_feature 9373..9477 FT /note="Match to PF00132 hexapep, Bacterial transferase FT hexapeptide (four repeats) Score 72.86" FT misc_feature 9391..9477 FT /note="PS00101 Bacterial hexapeptide-repeat containing-tran FT sferases signature" FT CDS join(9984..10056,10195..10252,10292..10381,10440..10476, FT 10521..10550) FT /db_xref="GOA:Q09714" FT /db_xref="SWISS-PROT:Q09714" FT /label=SPAC18B11.08c FT /note="SPAC18B11.08c, len:95, SIMILARITY:Saccharomyces FT cerevisiae, Q12160, hypothetical 15.4 kd protein ypr056c., FT (140 aa), fasta scores: opt: 103, E():0.18, (28.0% identity FT in 118 aa)" FT /gene="SPAC18B11.08c" FT /product="hypothetical protein" FT /protein_id="CAA90596.2" FT /translation="MAPAELKRPDLIVPYKARVKANEEVGLSLVSTATCMAALFLRFKL FT IAWVAFILTFSNLLNANTSPSSSPTSMAFMGIAALVSTYLPQFLNTPNKT" FT misc_feature 10057..10062 FT /note="gtaaag, splice donor sequence" FT misc_feature 10180..10194 FT /note="ctaaccctattatag, splice branch and acceptor" FT misc_feature 10253..10258 FT /note="gtatgt, splice donor sequence" FT misc_feature 10281..10291 FT /note="ttaacgagaag, splice branch and acceptor" FT misc_feature 10382..10387 FT /note="gtaagt, splice donor sequence" FT misc_feature 10425..10439 FT /note="ttaacatttgatcag, splice branch and acceptor" FT misc_feature 10477..10482 FT /note="gtaagt, splice donor sequence" FT misc_feature 10508..10520 FT /note="ttaacttgtgcag, splice branch and acceptor" FT CDS join(11244..11285,11333..11397,11611..11731,11837..11940, FT 11989..12112) FT /db_xref="GOA:P23566" FT /db_xref="SWISS-PROT:P23566" FT /label=rhp6 FT /note="SPAC18B11.07c, len:151" FT /gene="rhp6" FT /gene="SPAC18B11.07c" FT /product="ubiquitin-conjugating enzyme e2-17 kd" FT /gene="ubc2" FT /protein_id="CAA90592.1" FT /translation="MSTTARRRLMRDFKRMQQDPPAGVSASPVSDNVMLWNAVIIGPAD FT TPFEDGTFKLVLSFDEQYPNKPPLVKFVSTMFHPNVYANGELCLDILQNRWSPTYDVAA FT ILTSIQSLLNDPNNASPANAEAAQLHRENKKEYVRRVRKTVEDSWES" FT misc_feature 11286..11291 FT /note="gtacgg, splice donor sequence" FT misc_feature 11318..11332 FT /note="ttaaccaattcttag, splice branch and acceptor" FT misc_feature join(11333..11397,11611..11731,11837..11940,11989..12097) FT /note="Match to PF00179 UQ_con, Ubiquitin-conjugating FT enzyme Score 213.59" FT misc_feature 11398..11403 FT /note="gtaagt, splice donor sequence" FT misc_feature 11595..11610 FT /note="ctaaccatttgagcag, splice branch and acceptor" FT misc_feature 11732..11737 FT /note="gtatgc, splice donor sequence" FT misc_feature 11819..11836 FT /note="cttacttattggctttag, splice branch and acceptor" FT misc_feature 11837..11881 FT /note="PS00183 Ubiquitin-conjugating enzymes active site" FT misc_feature 11941..11946 FT /note="gtttgc, splice donor sequence" FT misc_feature 11978..11988 FT /note="ctaacttttag, splice branch and acceptor" FT CDS complement(12485..13468) FT /db_xref="SWISS-PROT:Q09713" FT /label=SPAC18B11.06 FT /note="SPAC18B11.06, len:327, SIMILARITY:Saccharomyces FT cerevisiae, YEV7_YEAST, hypothetical 40.8 kd protein in FT rsp5-pak1 intergenic region., (357 aa), fasta scores: opt: FT 204, E():2.6e-05, (27.6% identity in 308 aa)" FT /gene="SPAC18B11.06" FT /product="hypothetical protein" FT /protein_id="CAA90591.1" FT /translation="MDVLNKSIQTALEALPKTSSSSSDGVSLVSLKCQLLLSYVQKLAF FT LMLVKLDDESFLQHQDVVEKLVQLRIEIEKIRPLENRIQYSVDKLLRAAGRKEEIGSIK FT EPENNGNDKDSQDSLKLHYKPNLSEFADDSDGPASENNVVKEDDKSSISSEDEEEELRS FT AKDGIYRPPRIRAVTMDSEKRTRHRPNHLVDEFVSSDMSSVPQSMPSVGSNLEKRGRVI FT HADERELQKMRERIEYEESNYTRLPKLSKKDLKKSKRVKKHDYGGEDWSLLDRKFHDDD FT FSNRKLDLTSRAKRRANFEDVNDGSLASPVQIGQSYRKRKKNLKRR" FT CDS complement(13902..15182) FT /db_xref="GOA:Q09712" FT /db_xref="SWISS-PROT:Q09712" FT /label=SPAC18B11.05 FT /note="SPAC18B11.05, len:426, SIMILARITY:Saccharomyces FT cerevisiae, YBL4_YEAST, hypothetical 50.8 kd protein in FT coq1-flr1 intergenic region precursor., (433 aa), fasta FT scores: opt: 320, E():1.9e-13, (29.4% identity in 446 aa)" FT /gene="SPAC18B11.05" FT /product="hypothetical protein" FT /protein_id="CAA90590.1" FT /translation="MKLNESAMKNAEKKSNSYLAIRMTRSGYNYFKGICVCTFLLSTIL FT YLGIAVIMSHLCVFDDTAMLYLRQNRSRLAESNIFRTLFISWIRWDAIYFVDMAVNGSL FT FEQEWAFSSLWPKIISFLAFRSKDVVLLGIVSCFASIFFHAIACYALYLLTKSIFSNQK FT MTAYTVIFYCFSPSGIYMSVGYTESLFAAFSFLGLLLFIKKQQYPAAFLWSLATLIRSN FT GIFWCIFFGMPAIGTLKISLERLQLTFMQVSQLVGYGTKCLIILVPFFYNQYLGFKLFC FT PGVAWCNKSLPLIYPAVQEKYWNVGFLRYWTLNNIPNFLFALLSIIPILFALFYSISGS FT TLHSFRSIKSHLVLSALYLYIGCFHMHTQVLNRMSSALPLLYWSMAHATLYAKSRNLKA FT FGHCILFVWIVYTVIQAGLYGSFLPPA" FT CDS join(complement(16892..16955),complement(16820..16852), FT complement(16358..16701),complement(16180..16311)) FT /db_xref="GOA:Q09711" FT /db_xref="SWISS-PROT:Q09711" FT /label=SPAC18B11.04 FT /note="SPAC18B11.04, len:190, SIMILARITY:Mus musculus, FT AAD01642, neuronal calcium sensor-1., (190 aa), fasta FT scores: opt: 910, E():0, (69.5% identity in 190 aa)" FT /gene="SPAC18B11.04" FT /product="related to neuronal calcium sensor 1 proteins" FT /protein_id="CAA90589.1" FT /translation="MGKSQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNK FT SEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWA FT FQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQ FT LTLEEFCEGSKRDPTIVSALSLYDGLV" FT misc_feature complement(16228..16308) FT /note="Match to PF00036 efhand, EF hand Score 32.76" FT misc_feature complement(16246..16284) FT /note="PS00018 EF-hand calcium-binding domain" FT misc_feature complement(16312..16326) FT /note="ctaataattttttag, splice branch and acceptor" FT misc_feature complement(16352..16357) FT /note="gtttga, splice donor sequence" FT misc_feature complement(16415..16492) FT /note="Match to PF00036 efhand, EF hand Score 26.35" FT misc_feature complement(16436..16474) FT /note="PS00018 EF-hand calcium-binding domain" FT misc_feature complement(16529..16597) FT /note="Match to PF00036 efhand, EF hand Score 33.86" FT misc_feature complement(16544..16582) FT /note="PS00018 EF-hand calcium-binding domain" FT misc_feature complement(16702..16716) FT /note="ctaacaagtatgcag, splice branch and acceptor" FT misc_feature complement(16814..16819) FT /note="gtatga, splice donor sequence" FT misc_feature complement(16853..16866) FT /note="ctaacaaatccaag, splice branch and acceptor" FT misc_feature complement(16886..16891) FT /note="gtacgt, splice donor sequence" FT CDS 17785..19107 FT /db_xref="GOA:Q09710" FT /db_xref="SWISS-PROT:Q09710" FT /label=SPAC18B11.03c FT /note="SPAC18B11.03c, len:440, SIMILARITY:Saccharomyces FT cerevisiae, YG4K_YEAST, hypothetical 54.5 kd protein in FT zpr1-rta1 intergenic region., (468 aa), fasta scores: opt: FT 160, E():0.0018, (22.8% identity in 452 aa)" FT /gene="SPAC18B11.03c" FT /product="hypothetical protein" FT /protein_id="CAA90588.1" FT /translation="MSTGRLEIYSVKRNVLNMFSIVIVSATYSISLDSTVLYPAVYHAI FT VNQPMLGARIHNCHSKIPIVKKLKTIDLDKVVKYADDQKVDSFCNNALQNFKLCYDDET FT LPLWMVYVLNDKSELVFIYDHSLFDGGSGPLFHKYVLEGLQMSKTNFSSSTVPVSELPL FT PKNLEKLIDVHPSWFCLMKALWTNSGLPFSKGFRSPSYKGHAPVRPFSSHTIFFSISNA FT VVKNIKQLSKNIDASFTSIFYSVFMLSIYYAIAKNGKVNLDMLIDVNARRFLPVAKQTM FT GNYVFSYVHHLNGFQPSQRQEDYKHTMVDLATEFSHRLKAALSNPREMSQQIGLLSYID FT IEDYLLKSCEKTRGNTAEISNLGYFSFPADSSVKIKNMAFAQPCSSLSAPFVLNVITVA FT DGPCSFSLSIFDDGNTEQTHELAIKIRDKFLSILEKVSMNS" FT CDS 19551..20735 FT /db_xref="GOA:Q09709" FT /db_xref="SWISS-PROT:Q09709" FT /label=SPAC18B11.02c FT /note="SPAC18B11.02c, len:394, SIMILARITY:Saccharomyces FT cerevisiae, YD36_YEAST, hypothetical 53.4 kd protein in FT prp9-nat1 intergenic region., (462 aa), fasta scores: opt: FT 1120, E():0, (47.8% identity in 393 aa)" FT /gene="SPAC18B11.02c" FT /product="hypothetical protein" FT /protein_id="CAA90587.1" FT /translation="MLKRPKRDPLKDCEYVFKGDGLRRVPPYYYEYITFAKLRWYGKTL FT LEVFNTEFRDRESGYYEKAIRNGQVKVNNQIGNVDTLIENGYIVSHHAHRHEPPVSDQP FT VGIVHEDESYVVIDKPAGVPVHPTGRYNHNTVLHILMKENKCSLLYPCNRLDRLTSGLM FT FFSKSPKAAEEMRVHMISKSLKKEYVARVIGEFPNSGEVICDAPLLTVAPTLGLNRIHP FT DGKEASTVFKRIAFDGHTSLVLCKPLTGRTHQLRVHLQYLGYPIANDPIYANKRVWGPS FT LGKNGEGSNESVIMRLSEIGKTETASPLLQYEWYTNETEAEAKARRDKRLGELLTGKHC FT SECGTPLYSDPSPEELGIWLHALKYESKDWSYKTQLPKWALDVCCRDPNALPIE" FT misc_feature 19872..20342 FT /note="Match to PF00849 YABO, Hypothetical yabO/yceC/sfhB FT family Score 232.59" FT misc_feature 21228..21536 FT /note="Match to PF00752 XPG_N, XPG N-terminal domain Score FT 183.41" FT CDS 21228..22718 FT /db_xref="GOA:Q09708" FT /db_xref="SWISS-PROT:Q09708" FT /label=SPAC18B11.01c FT /note="SPAC18B11.01c, len:496, SIMILARITY:Oryza sativa, FT BAA36171, fen-1., (380 aa), fasta scores: opt: 321, FT E():1.2e-13, (29.4% identity in 218 aa)" FT /gene="SPAC18B11.01c" FT /product="putative excision repair endonuclease" FT /gene="SPAC12G12.16c" FT /protein_id="CAA90586.1" FT /translation="MGVHGLLPIIRKVASEGIRWLQPEFFSKYYPVLAVDGNLLLYRFF FT RSPNTPLHTNYQHVLWALKLSRYCRKLKTSPIVVFDNLKPNDFKAEEHEKRSLISSQIV FT NQRQVVQEQMYFLCNLKNCLIDNNFPTGNFYYEIGPLLSQIGKLLFDLRSLNERDNPFH FT AQNNAENLENATFVRLIVDKLNDREKTLMIQEKKNHLIHSLRQLLAFSEINDFPSEIRS FT YLEFILSNLDLECLTLCLKIIKGILTLDELQKAIKLKQTELDKLERRLYRPSPQNIFEI FT FEILKILGIPASFSPIGVEAEAFASAISQNNLAYAVATQDTDVLLLGSSMISNFLDLND FT NFHLPLQIMDPRKIAQELNLTFDGFQDYCLMCGTDFTSRIPKIGPVRALKLIRYYGNAF FT DVLKALNVEEKYIIPTDYIKKFLTAKKLFTDLPSNNELFSFIHNIPKEFLHLSDSTYLD FT LEKQVLRIFNVQIEELDAKTPWYYHYELEKDVKSTYEY" FT misc_feature 22083..22364 FT /note="Match to PF00867 XPG_I, XPG I-region Score 148.50" FT misc_feature complement(22488..22847) FT /note="nominal overlap with cosmid SPAC12G12, EM:Z66568 S. FT pombe chromosome 1 " XX SQ Sequence 22847 BP; 7625 A; 3884 C; 3908 G; 7430 T; 0 other; gatcataaac tttttgtatt cttctttggc ttaatcaaac atatgaatac aaattgtatt 60 ttactttatt ttattttttt tataaattca atacattcat tttaataatt tgcgttctat 120 gagcactgaa atttaagccg ttaaatgcaa aaatattatt ataacataaa aaaatcgagc 180 ttaaatataa ataatataca tacacaaaga gtaatgttca aagctatcaa cataaaaaga 240 taaagagatg attaggataa attgcagctc atgatacatc aaggaagtta aaacaaaaaa 300 ttccagactg aaaagcatat aagattagtt cgtttaaata ttgtcctaac aaggattaca 360 cataatgtat aaccaaaagt aaaatgctat tttatatgac catccgaata ttcccaataa 420 gtctatagaa ataatgtgaa atcaaatgtc ttatcagaag gcaaagcaga agactctctt 480 tgcgtagttg gaacttgatg tatggtatat aatgtatcaa tatactgttg tctgaggagc 540 catggatgaa catatgcaaa attctcaaaa atcatttgat ataagcctat atcagcaaga 600 tatgaatgaa gtagtggtgc aatagaattg gtggaaatga tttggtcgag tttccaaaaa 660 ctttgatggg aaatatccgt accagtagta atgatttcaa gtttaacatg aaacagagtg 720 tcaaacattt ttagagcatc caaatgagaa tccaatgaaa ttttgataat aacaggaaca 780 tcgacagagt cccagttcaa tgaatccggc cccactaaat catctgaacc aatgattatg 840 aggctactat acaaagaaga ttctaaagct tcagcaggat cggagacata gcggaaaatc 900 atttctatag ttttgctttg ccaaacataa attgtttctc cattatcaag ttttttttca 960 tgaccaaagc tttccagcaa acgataaaaa agttgccaac ccacagtagt atttatatca 1020 ctaacatctc ctgcttgaag cgcaacggct atattaatga caggctttgt gtgagttgca 1080 tccaagcttt gtattaattc ttcggttcta gcatctggct ttattaagat tggttcctca 1140 tcaggactgt ccaacggtga aagaacagtt tccatgaaaa cgtgacttgc agcaatttct 1200 tgaagatatt tttgttttaa ttcactacta accatgcttt gctccatcat caaacttttt 1260 tcaaaagctc cacgatcacg catgtttcgc caaaagcgat aaatagtagt acctgacatc 1320 cttcgaagga tcatttgata atccccagtt tcatattcag cattaatcgt tatcacacaa 1380 ccacgataaa gccaagattt agaactactg ttaaaatgaa atcttgaatc actaggataa 1440 ctttcaattc tttcatcaga atatgtgtaa cgtaataaca actcataaaa taccctttcg 1500 taaccttcaa agtgcgatcc attttttaaa tttaagaatt cctttaacaa aaatgatgca 1560 agttgtgctc tttcagtagt ttcacaccct aagaaaaggt ttgaaattat ggaataagaa 1620 aaggaaacta aatataaaca aaaaacttta gtatttggat taaccaactt tttgtgacca 1680 tcaagttctt ctttttttgt ccggataacc tttaagcaaa aaagacagat gctctgaata 1740 gtttcttttt ctaagccttc attcaattcc cagttgtcgc tcaccacgtg aagaagtcga 1800 agaaaattga ccaaactacg ttccgataaa ttagaagaca ttgtaataga aaaaaattta 1860 ggtagatgca taattgaaaa tgactgcatg gcacagcaat tagttattag agtatcgata 1920 catgactcca ttgttttatc tcccttttca gcgaaacgat tgagtaattg gaagaattgt 1980 tcatgagcag ttggaggtag aacatcttta taaaccatca aaacagaaag aatttttgat 2040 agactgacga gcaaatcctc aattcgaaag aaatccgaaa aatttatatt taatgattgt 2100 ttaccattaa tgatgtctct taaagagttc aaaaggagct gtaaagcttc aacagttttt 2160 gtaaacatct ttgtgtttcg aagctgatta gtaaaattaa tcaatatgta ttgaacaact 2220 ttccaatctg tttcatgggt aacaatatac ataacatttt ttacccattc attaatcggc 2280 aaactcatta aatcctttga caaagtagct gaggtattca ccttcagggg aaacttttga 2340 aaaactggag aaaacgacaa atctctgtcc tttactttat tgtcccgaca gcgttgagct 2400 tcttcagata taaaagggtt atgccattgc gtactatata cagatattaa ctctaactga 2460 gcgggagaca agttaacaaa acaatagtca ttagtgttta ttcgtagttg taataataac 2520 ttcaatactg gaattcgaaa agtacgtcga attttgaaat cacacgaaat ttcgaccaac 2580 ccatcgtaaa gcactgattt aaattcgggt agcaaaacat aataaaatgt taagcttact 2640 attgcctgaa tagatctaag ttgtaaatcc ccattactgc tgttatgagc ataaaagcat 2700 aatgagtctt tcacctcgtg aaatacattc gatggatata tccaagataa atcacaaact 2760 aaggaaataa cttcatcaat tataacttcg gaactagatt tatccaaact tttcactaag 2820 ggacaaagca ttcgagcata cacttcaggg cgaagttcaa ctggacaagc aaatagaact 2880 tttctaaaga gaccaattaa gtagacatgg aaatccaaag aaaaactagt atcaaaataa 2940 gatttaagta gaattgtttg atcctcaagc catccttccg aatatggcaa ctgtgatcgt 3000 aaatcaagaa cagtaaacaa cttttggcta agtgtagggg ttaaatatga aaaattaatt 3060 ttcaggaact catgaaactt ctctagaaca aaatgattag agtctggttt taaaatttcg 3120 ttaaataaaa gaagatgttg taattgatac gatgcaatag actcaattat attaggctca 3180 atgtgctgcc aagttccagg tcggtaattg agagatttag gaagtgatga agatatttca 3240 acaagcaaat ctaaaaggct gatccattca tctgcataaa gcacttcaac aaaagaacgg 3300 cgctccaaag cattatataa agaacgagtg gtttctaaag ctattcgact agatttattc 3360 tttaaggatc tttgaaggaa tccaagcagc attcctctag tgcaatacac tgatctaggg 3420 atatcggtaa agagagcact cacgatttga ataccaccca taatcgctat ataagaacct 3480 tcatctgtct cttccattat ccgttttagg gaattaagtg cttcgtactt ggtcgctgtc 3540 ttcaacagtt tctcaacaat ctgctgagct gattgtgagc ttgcgactaa gccaaatttt 3600 gctcgacata ctacttcaac aatagaatac aaaacagcgg aagatatgcg accataggat 3660 ataatacaat ttaataacga aaaaactaat gcaatgtctt cttcatcggt ggtgcttttt 3720 gagacccaca cacaattcgc tagcatagaa gaaacctcca tttcatcaaa taaattaaag 3780 cccaccctga acatattcgt aagcaagaga attatctgac gaaaacaacg ggtgtaattt 3840 ctcaattcag cacttccttt gaaggatttt ctcgactgag ctcgcatatc atcaataatc 3900 gtaaataaat cagtcaacca ttcagacaaa actttaagta tgtcatttga aaaagactca 3960 gttctttcgc cttgggatgt aataacaatc aaggcgtcta cagtagcagg atagtattca 4020 gaattcggaa cctttgacag ctcgttgaat aatagtgcac ggtcatcgga agacatttct 4080 ttatgctttt cagctgcatg agtccataag gaaatagtgg ctgccagtat gtttccgtga 4140 actttatttt caataatgtc tttagtggaa tcaacaagtt tttgtaggat tacattttta 4200 caaaactgct cattgttgat gagccttttt atgcgtttgt agcgtttatc caatgactgt 4260 tgattcgata tttgggtgag aatcgtgtct atatccaaag ccttcatagc ttagatataa 4320 atcgatgcag caaacaacga caatttttct ttaacccaaa cgtaatatag gtcctgggtt 4380 ggcaccgatt taagtattaa gattttaaat atatttaaaa agtgctaaat taaagattta 4440 atgaagtaaa cccaaattat agactgctta agccgtggag gattattata aactcctgaa 4500 aagatagcct taagaaacgt gcagatatcg aactgtaacg gattgtaaaa gcacacctca 4560 atatagcatc gattaggatt tattcaattt ctatgtttta gtcaataaaa tcgaaacaat 4620 gagtcttctt cgcgttgaag aagtcagaag atggttaata catacataat tttagcgagt 4680 atatgataaa tctgttggtg aatttcggag tcaaggtgga gatatgcaaa ttactaaata 4740 caagaataac catttaaaaa atgtttaatc aaccacatgt atttcaagaa tctacattga 4800 aaagtattaa gtattatctc aagttatgca acatttatca tagaactaaa attaaaaatt 4860 aaggaatttt ttattaattg tttatttttt aaataaaaag tgtctcagtt aatttatgag 4920 agaagccatt ctccaaaatt agtgacatta aaaaactgag tgatgatttg tctattgtga 4980 ccgtaagtaa aggaaataat attgcaaaaa aaatatgata caaattaagg aaatatacca 5040 gtgtagtaat agagtttaca aaatttagtt tgtaaacttt gtaaccaaaa atcaatgcgg 5100 ttaactattt ccgagagcaa atagttatat gtaaacagga acaaaaattc aaggagatgc 5160 agggtcaatt gaccatatgc gagcacgtaa atcaccactt cccgaagcaa attgcctacc 5220 atctgggcta aagcatacgg aaataactga attcttgtgt ccttgacaag tgagataaga 5280 ttggcctgtt tgcaaatccc agaattgcat acttctatcc ttcgatccgc ttaatcccca 5340 acggctgtcg ggtgaaacag ctactgaaag aacaaaatca gtatgtcctg tataggtggc 5400 tttgcaaata ccttcaggct taatagctga aaggccaact gaacgagttg cttgtaattc 5460 ccagactttg atagtcttat caagacttcc actaagaaga atgctgctgt cgggcgaaaa 5520 ggcaatagaa taaacactct ccttatgacc ttccaatcgt tcaaccaaag tacccgacac 5580 agaccatact cgaattatct gatctagact accaactgca atgaattgat catttggaga 5640 gatggctatt gccgtcacac cattctcaat ttctaacttt aaaatacatt gacctgtctc 5700 cacatcccag agtcgtgcag ttcgatcgcc actaccagag acgatgaatc gcccattatg 5760 gctaaaatct aaggaataga tatcttgttc atgacctgaa aatacgtaac gaactttttg 5820 agttgagaga tcccagagtt ttatttgacg atcttctgtt cccgtgacta aatacttacc 5880 atcagggctg aaagcaatgg ttctcacata caaatcacgg gaaggatcag gtgattcttc 5940 atgcaaagta aaaagttttt tgccagtctg aacatcaaag acattagcgg cctggttaca 6000 gccagttgct aaatacttgc cattgttact aaacttaacg cagcaaacaa cactgggatg 6060 ctctagtgtg tgcacgagat taatattaaa aacccttttg catgctgggt tataagtgac 6120 gtaccaactc tgagaagttg tctttctagc agcttctgta tctgaaactg gagcaatctg 6180 ttctcttccc tgatattctc catcaggacc cgcttgggat atagaaccag cattcgcaga 6240 agcagtcata gaaggttcag ccgaaggagt tgctttggta ggaatacgcg gtggctggac 6300 attcacagca ggttttgaag tagcacttgg attataataa ttggaaacac caggcaattg 6360 aggatttggt tgttgagaaa cctgatttgc tccgtaatta acaggaggga tatataaagg 6420 tgtagtacta ggtaaattgg atgtagatat cgcgggattt tgagaagcaa ttccctgatt 6480 aaaattttgc ccgctagaag cctctactga aggaggaatt ggaggcatca atacttcagc 6540 aacattattt tgaggataag ctgattggtg aattggaggg atttgctgaa aggcaggtag 6600 atggttactt ggaggctgag aagtagattt ggtttgagag ggatgttcct gatcaatatg 6660 ggtaacttga ttattagaag cggcaagttc agatctttct ccacgatttc tataacttgc 6720 ggtattcgct tcgacaccta attcttcaag ctctcgcttc aacttgttga tatctttttc 6780 gtacctataa atgttagtaa attggtgaag acagatgtta taaaggtttt ttttttttta 6840 cttcaagcat ataaatctcg agcgacacgt atgctattat aaaataatga tgaatttcac 6900 agaaaagaag tagatactat ataatccctc gataccttta acatataaaa acttacgttt 6960 ctctaataga tttttgtttt tcatacatat catccacggt ttttcggaac gcttcaattt 7020 cttgaatttg agattgtatc actgcaatag aacagaatgt tagtttccaa aaaatagcta 7080 atttaattta ttttattcaa acacgtacta gaagattcat agtcgtttcc gcgcgccttg 7140 gacgcgaagc tatgatgagc caaagcattg tattcagcct tcaacgcatc cagcatttct 7200 tgaactttcg tggcatcctc cactgacgcc attttttttt tcagtcagac ttattgcaaa 7260 aactgaatcc gattgatata cgccctttta caacaatagc aacacttgaa ttgtggtaca 7320 agaataaact tgtgttcttg aacgtttgta gcagcacttt tatcgagcgg ctccttgtgc 7380 tgcgctaatc tttaaataga gaatgtggtg ctacatattt ttggttgagc aagtatcaca 7440 aaattagtat ggcgtgtgtg ttggcaactt gtcccaatta ttttgaaatt catttgaatt 7500 atagagaaaa gcaattcgaa accctttact gtttgatttt ttgtagcgtt tatattattt 7560 ttttgaatat agattttctt gcttttcagt tgatgtttgt tataaaaaaa tagttataac 7620 tttgaaacgt agtgtaattc attttttttt tattgatgga aaaatttgtt aaccgttttt 7680 atatatcaat ataaaaaaat taaaatttgt gtttaatcaa tttattatct gatccttgtt 7740 taattagatt gtttaccgac ctttgtaaga cattattaca gtgagtttta tcttgataag 7800 tattaattaa aagttatgat agtatttaac ccgtaaattc acatttcatt tgctaatgac 7860 tcagttaatc ataagtgaca ttatttgttt aatgatgcga aatttgacgc actttactga 7920 tattaaaaca ttgttggttg tcttaaagat gcttttttca tataatctag ttatcatgaa 7980 gaaggatgaa aaaatcccat agttgaaatt tattaacact aaagcaaaat gtttaagcgc 8040 agcaaaccga agccgtcaga aattgagcat ttaatctgac acgatatgcc atttacactt 8100 caagggcgat taataaatac actttggatt tatttttaaa tcatatttat tgcttattta 8160 cttatcaatt tttgtttgat gtactattta agttgttttg aatttttttt ttatatgaca 8220 ttagtttggg attactaccc agtttaatca gtttaatgat acaggaggaa agcaagatta 8280 aaaaagggac ggacaacgtt cattgcatat cttgttattg cttgtcagtt tacggccctc 8340 agcgtttgtt aagctacact aactatttac ttgtaacttg ataaattttg gtatgctggt 8400 ggtaatacga gtaggggcca gacataaagc aatgcgacaa ttaatgatat gttgcatagt 8460 ggggcataat gtagtgtaac agctgacgct atatatcatc gagatgtttt tacttacgtt 8520 ttacaaacta tttcactaaa aagtttccgt atagttttat cagcaatttg ttaatattga 8580 tatcaataca tatatatata tatatataag tctatttata catcgataac tctactagtc 8640 ccattgtcaa tgctagtgaa tatacttgtt ttccgacaga aatgactcgt actcgtgtac 8700 aaaaaatgat accgaaaacc attgaatacc aaaaaatgat atctggtcaa ccgtaaggct 8760 aatgcttaaa acttgtcgag ctaatatatc atcttcgttg acatgtttga agtcacattg 8820 aacgcaggga gatattctaa ttactaaata acaggtacaa ggcttacgac gaggagttga 8880 ctcaagcgag atgtaatgct aaaaaattaa tgcgaaggtt taatgacact atgggagatt 8940 tggaaaatgt aggcccagca gaattgatta aaagacgagc tgaactgttg gctgaagttt 9000 ttgtatttga cgaatcttca gcaccagaga ttgagccacc tatggctttt gattacggat 9060 ttaacgttca ttttggaaaa aaattctttg caaattataa ttgtacattt ctagatgttg 9120 ccataattac tattggtaat aatgtaatgc taggccccaa tgtatgttta tatatatata 9180 tagttacttt caagtcattc attcaaaaaa taaatatact aatggtgtct ttccaggttc 9240 aactatgtac agcaacacat cccttggatt ttaaagcaag gaactccgga attgaatttg 9300 gtttaccaat taacgtatgc gttagtccag ttattgaaac atcttacaac taacaaacaa 9360 aattttatca agattcagga caatgtttgg attggtatgg gagttatagt tctcccaggt 9420 gttactatcg gggaaggcag tgtaattgga gcgggtgctg ttgttacaaa agacatccca 9480 cctaatacgt tggctgtagg atcacctgcc aaacctattc gtaaaattga aaacgagtga 9540 acgagtgtaa tttttttttt tattatttca tctaacgatt aaatgctctt tgaacttctt 9600 aagttcacct ggcttggttc ctaaattttt aaaatagtat aaataatatt atattatgtt 9660 tgagctttaa attgttatat agaagactta gaatgctaaa agaaatccat ttctcactcg 9720 ccaagtagga tcagtttcct cctatgactt gctaaagccc ccacgtggta ctgcaatcga 9780 ttttaattct aatgcttagc caagtctaaa atagttgaaa ttcttagtgg gataagaact 9840 cttaaccccc acgatatatt tgaatgctaa ataacctaac ctaaaaccat tttacacatt 9900 ttattactaa cttcattata ttcttgtaga ggaaccatcc cattcaccag ttctgaagtc 9960 tcgacaacga aaattcataa aatatggcgc ctgcagaact taaacgacct gatttaatcg 10020 ttccctacaa agctagagtc aaagcaaatg aagaaggtaa agtagaaagc actttcaaat 10080 tgaacccaat cgtgagttac gctgatttaa tcgctcaagc tttagttcat tgtggaatat 10140 tttaaatcct ttctttcgtc aaataattta ttaagtttgc taaccctatt atagttggct 10200 tgagtttggt aagcacagcc acgtgtatgg ctgctttatt tcttcgtttc aagtatgtaa 10260 gatattttag gattttcatg ttaacgagaa gattaattgc atgggttgct tttatcctaa 10320 ccttttcaaa tttactgaac gcaaatacgt ctcccagctc atctccgact tcaatggctt 10380 tgtaagtaat cctaattcat tgcattaatg tagttctatg gatgttaaca tttgatcagt 10440 atgggtatcg cggctcttgt gtcaacatat ttaccggtaa gttgaatttt tatatttact 10500 ttgtcgatta acttgtgcag caatttttaa atactccaaa caaaacttag taatttttaa 10560 gtcagtgaat taataagagt attaagctga tttttttctg gataattaaa tttatgcaca 10620 atgtaaatat ctaatggtga agagttcaga tacatttcta actaccattt caatcacgta 10680 gcagacgcgt aaaaaattgg ctgtttgtgt tttctcattg ttaagctagt gaaaatgtaa 10740 atttatttct tacatcctgt tgctctttca ttttttcttc ctaatgtatt ttagttgctt 10800 ttttaaaccc aatgagaaca aaggcttaaa gtaaatatat ataattttca catgttcaac 10860 agtttaccgt taacaaatgc acggaccttg attatgatta atggttgaat gaaaaatatc 10920 aactttcctt atctttaact ataatttaaa tgaagtagta gttcattaat actaaagcag 10980 acttgcattg caaatgctga acattactaa aaggttggtc tagttataag gtaactgagc 11040 gtgcacttta ttattttaac gtgttgggtg cgccccatta ataatgaaat actgcatatg 11100 agtgaatggt cctactattg ttccctgccc ttctccaaca acgcaaatcg gatatcctaa 11160 ctcggtgtaa ttccaaggcg atatcgatat ttgtgcaact tttttttaaa gttatcacaa 11220 atagaagaga ggttgctata aaaatgtcaa cgaccgcaag aagacgtctc atgcgagatt 11280 ttaaggtacg gcagttgtgg atccgagaag acttatatta accaattctt agaggatgca 11340 gcaagatcct cctgctggag tttcagcttc ccctgtctct gacaatgtaa tgctttggta 11400 agtgtttacc tatgtcaatt catttttctc ttattgttat gcaacgtaat ggtgaatata 11460 tgtgctatat attgaatgcc ttttttgcca tatatttagg aaggagatcg tttcaaaatt 11520 cttacaagaa gcgatctttt tatgcttgtt ggtttctgga ttgattgctt ttgtttttta 11580 ttattgatgt tggactaacc atttgagcag gaatgctgtt atcattggcc cagcagacac 11640 tccatttgaa gatggaactt ttaagttggt tctttctttt gatgaacaat atcctaataa 11700 acctcctctt gtaaaattcg tctccacaat ggtatgctta gtcattgtat ttagacaagt 11760 cttaaattag attatttgat ttgttgtaat ttactttttt cttggttttt tttgtttact 11820 tacttattgg ctttagttcc atccaaatgt gtacgcaaat ggcgaacttt gcttggacat 11880 tctgcaaaac aggtggtctc caacttacga tgtggcagca attcttacct ctattcaaag 11940 gtttgctttt cagaaatatt acttaaattt ctcataacta acttttagct tacttaatga 12000 tccaaataat gcgtcccctg caaatgccga agctgctcag ctgcatcgtg aaaacaagaa 12060 ggagtatgtg cgtcgagtac gaaaaactgt agaagactcc tgggaaagtt gatttcaaga 12120 catagctgtc ttaataatcc ctatttcatt agaacttact cttctttttc aaccgccttt 12180 cacattaaat ctatttaagt gcttcaaagt tgccaaaatt gtaactatag taaatcatta 12240 agattttttt gtttacatct acgaatgaat gatttcttcc ttatgtttag aacttgtaaa 12300 ctatattaat gtgcgactaa tcacatatac agacatgtac atgcaaaatt tatattgatc 12360 ttattaaaca taacctgccc taaaccacac aaaaatacca aaccaagcgc aaaaactcca 12420 tttttttaaa tacatatggt caattttttt aagtaaacct caacggctgt tcccaaaata 12480 atgattaacg acgtttcaaa ttcttctttc ttttacgata tgactggcca atttgaacag 12540 gtgaagctaa tgagccatcg ttaacgtctt caaaattagc acgtctctta gctctagaag 12600 tcaggtctaa tttacgattt gaaaagtcat cgtcatggaa tttgcgatca agcaatgacc 12660 agtcttcacc accataatcg tgtttcttta cacgtttaga tttctttaaa tctttcttcg 12720 ataatttagg aaggcgagta taattacttt cctcatactc tatcctctca cgcatttttt 12780 gcaattctcg ttcatcagca tgaatgacac gtccacgttt ctcaagattt gaacctacac 12840 tcggcatact ttgaggaaca gatgacatat cagatgagac aaactcatcc actaaatgat 12900 taggacgatg ccttgtacgc ttttcggaat ccattgtaac tgcacgaata cgaggagggc 12960 gataaattcc atctttagcg gatctcagtt cctcttcttc atcttcagaa gatatagagc 13020 ttttgtcatc ctcttttaca acattatttt cactagctgg cccatcacta tcatcggcaa 13080 attcgcttaa atttggtttg taatgaagtt tcagggaatc ctgagaatct ttgtcatttc 13140 cattgttttc tggttcctta atagacccta tttcctcttt tcgaccagca gctctcaaca 13200 acttatctac agaatactgg atgcggtttt ccaaaggtcg aattttctca atctctatgc 13260 gtaactgaac aagtttctca acgacatctt ggtgttgtaa aaaactttca tcgtccaatt 13320 tcacaagcat tagaaaagct aatttttgta cataagataa aagcaattga cacttcaaag 13380 atactaagga taccccatcg cttgaggatg atgaagtttt aggcaaagct tcaagagcag 13440 tttggatgct cttatttaat acatccatat ttcaatatgt taatgtattg cctcaaaaat 13500 acaaacttct taaagtattg ggtaaacaat tagttggtgt gtacgctaga ataaattgct 13560 gaatcaaaaa tttgccataa cccagtatgt aattacggta ttttgcagcg ttacgctatg 13620 tgctcataaa gtacagtttg acttgaaaat ggaatagtct gaaaattgta ctgacttgaa 13680 aagtcagtaa gtttattaat gtacccaacg gggttacaga tgtcaaatca gtaggaaatt 13740 aaacattcag cgagttgtta acttcaccta caattagcat attttaacat tgtttcagag 13800 atgctcacta agtttttatt atagatatgg ctaaaagtgt tgtttttcaa gtaaaaaaat 13860 gttataataa aattaagtaa tcatgaattg agtgaattaa attaagcagg tggtagaaaa 13920 gatccataga gacctgcctg tatgacagtg taaactatcc atacaaacaa gatgcaatgg 13980 ccaaaagctt ttaagtttct ggattttgca tacaaggttg catgagccat tgaccagtag 14040 agaagtggaa gagctgaaga cattctgttt aaaacttgag tgtgcatgtg gaaacagcct 14100 atatagagat ataaggcact caggacaaga tgcgatttga tggatcggaa actgtgtaaa 14160 gtggatccag aaattgaata aaacaatgca aataagatgg gtattataga gagtaaagca 14220 aataaaaagt ttgggatatt gttaagggtc cagtaacgca aaaatccaac gttccagtac 14280 ttctcttgga ccgctggata aataagaggt aatgatttat tacaccaagc tactccgggg 14340 caaaataatt tgaatccaag atactggttg tagaaaaagg gaacaagtat aattaagcat 14400 tttgttccat aaccaactag ctgggaaact tgcataaatg taagttgtaa tcgttctaag 14460 cttattttta aggtcccaat agctggcatt ccaaagaata tgcaccaaaa tattccattg 14520 ctacgaatta aggttgcaag agaccacaaa aatgctgcgg gatattgttg cttctttatg 14580 aacaaaagca gccccaagaa actgaaagca gcaaagagtg attctgtgta acccacggac 14640 atatatattc cagaaggaga gaaacaataa aatatcactg tataagcggt cattttttga 14700 tttgagaaaa tggacttcgt taataggtaa agggcatagc aagcaattgc atgaaaaaat 14760 atagaagcaa aacaagaaac tatgcctaaa agcacaacat ccttgcttcg aaaagcaaga 14820 aaagaaataa tttttggcca taagctagaa aaagcccatt cttgttcaaa tagagaacca 14880 ttgacagcca tatcaacaaa atagatagca tcccatcgaa tccaagatat gaacagggtt 14940 ctaaatatat ttgattcagc taaacgtgat cgattttgtc gtagatataa cattgcagta 15000 tcatcaaaaa cacacaagtg tgacattatt actgcaatgc caagataaag aatcgtagaa 15060 agcaaaaagg tgcaaacaca gataccttta aagtagttat atcccgacct agtcatcctt 15120 atcgctaagt aactgttcga ttttttttct gcgtttttca tcgcggattc gtttaatttc 15180 attatgtatt tcttctggtt cttttggtaa ttccttttct tgagtatccc agaatgttga 15240 ctagtatttt gttaaaacag gtcttatata caaacataca tgttcaatat gttttcgata 15300 ataactagga tgtccaatat aatacattgc tgctaaagga agcgcacaat ataaagtaaa 15360 ctttttaatt agtatggttc ataccttatt taaaaatgaa tattcatacc ttgaaaaact 15420 ccaagttcag gcctgccatt aagaagttgg gtgttgccgt actagggtta agcctactaa 15480 aattgcaacg tctttatgcg aagcatttat acataagaaa tttctcaaat gaatacactc 15540 ataaatgaat tgaaagccac aaaattagta tttaaaaaag ataattactt ataaatatct 15600 aaatcgacta tcagggtgat aatctataaa gacaacctaa agcttaattt agctaagcat 15660 gaccacactc attaaaatgt gtgaaaaata gatgattatt aatggagaat atattaacag 15720 taaaagaaaa gtaacgtttg aaaaactcgt aaaagatgtc aattcgtttt cggactaaat 15780 taatttaact gccctagctt tcaggtacaa ataatccagt gattgcacaa gaatatatga 15840 aaaccgcatt gagcaagaac ctatgtaaaa atgtctcgcg ctgaattatt tataaatagt 15900 ttcttgaatt ttatctaaag caagagccta aaaccttcat tatattaaaa aatgtaataa 15960 aaggcaaaat gtactttcat tgagtgaagc aaaaaagaac aaggaagtaa gccagaaaac 16020 aaacaacaga tatgttaagt aaaagcacag taaaactacc ttattaatct caccaacaaa 16080 aaagttgaga ggtagacaga taaaaacgaa aatgtagttt aatcgaagat atatatgcag 16140 aagaaaactt tgataataat gcatactagg ggtgaaaagc taaaccaatc catcgtataa 16200 agaaagggct gacacgatag tcggatcacg tttggaccct tcgcagaatt cctcaagtgt 16260 cagttgccca tctttgtttt tatccatcat attgaaaatc ttgttgacgc gctaaaaaat 16320 tattagacat tatgctcaac atactaaata ttcaaacctt ttcaggagta tcttcatcct 16380 ccggtaactt gaccatgcta ccaaccattt tgtagatagc atcaacaatt cgtagcattt 16440 cgtcgtaaga aatcaatcca ttattatcaa gatcgtataa ttgaaatgcc catataagtt 16500 tatcattcag ttcacctctc gaagtcacac ttaaagcaca aatgaattct ttaaaatcaa 16560 tgtatccatt tttgtcagca tcaaaaacat taaatacata ttcagcgaaa gcactcggat 16620 caccgaatgg gaaaaattgt ttatagattt tctgaaattc agacttattc aaatggccag 16680 aagggcagtc tttaaaaaac cctgcatact tgttagattc agcgttaaac attcaattta 16740 gcagcaatta agaatcttat tcaaattgca gaaccatgat gcggatgtaa aatcaatttt 16800 tttaggatag ctgtcatacc tttataccat tgttgcaatt cctttttatc aacttggatt 16860 tgttagtatt gactagtttt acaaaacgta caccttgtag aacgaactaa gtcttggagt 16920 tgatcttgag acaattttga ttgtgatttt cccatcttga agacaagtta atcttttctc 16980 agaggatagt tggtttaatt tataattttt tttaagtaac ttgtcggata ttaaagttgt 17040 ttagcaatta gcagtagttg aagttgggga ggcgcagggt aaattgagtt gtcaatcgac 17100 aagttgtaac tagtgttaaa tggtattaaa acagttccta tttggctcat tataaaagta 17160 aattcatctt tttttaattc taagatatgt aaatttacgt atacatgttt ggcagaaatt 17220 tattagaaaa tttttaaact agtgtattcc agatatataa caatttatgt gaataataaa 17280 atatgcaagc tttgttgata cttatgtgaa cgaatataaa aaaatattta aatagtaagc 17340 ataaaaaatg attttttata gatcactgaa aacatcaagt tgatgttttg aaagttcatt 17400 tgtacattag ttattgatct tgtagtttta cctttaccat cctttattac agttcagaaa 17460 atacattttt tatattttaa atctatctgt ttcaaaaata aaaatatgaa caaagtagct 17520 ggaatttaac tacaattgat tatcgatgga tattgagatt ccactgcgcc gcttggtaaa 17580 tttatgtaaa ttttcatttt ttacgcgttg aaataactca ccactgatta aatagtgcat 17640 tctctcatta ttcggtttca aaactattga attgtcgttg aagcaaagct attaatatca 17700 ttatggatac ctacatggaa gaaagagaag caggttggta attatgttta acatttcttc 17760 gattttctaa tcattttctt actaatgtct acaggacggt tggaaattta ttccgtcaag 17820 aggaatgtct taaatatgtt ttctatagta attgtttctg caacttactc tatttcgctc 17880 gattcgacag ttttatatcc agcagtatat catgcaattg tcaatcaacc gatgctaggt 17940 gctaggatcc acaattgtca tagcaaaatt cccattgtaa agaagttgaa aacaatagac 18000 cttgataagg tcgttaaata tgctgatgat cagaaagttg atagcttctg caataacgct 18060 cttcaaaatt ttaagctatg ttatgacgat gagacacttc ctctttggat ggtctatgta 18120 ctaaatgata agtccgaatt agtttttata tatgatcact cccttttcga cggaggaagt 18180 ggccctttgt ttcataaata tgttttggaa ggattacaaa tgtccaaaac aaatttttca 18240 tcttcaaccg tgccagtatc agaattacca cttcctaaaa atcttgaaaa actaatagat 18300 gttcatcctt catggttttg tctaatgaaa gcactatgga caaactctgg acttccgttc 18360 tctaagggct ttcggtctcc ttcttataaa ggtcatgctc cagtgcgtcc attttcatcg 18420 catacaatat tcttttcaat ttctaatgct gttgttaaaa acatcaagca actctcaaaa 18480 aacatagacg cttctttcac ttcgattttt tattctgtct ttatgctcag tatatattat 18540 gctattgcta aaaatggtaa agttaaccta gatatgctca ttgatgtgaa tgcgcgccgt 18600 tttttgcccg tagccaagca aaccatggga aactatgtgt tttcttacgt tcatcatcta 18660 aacggttttc agccaagtca gcgtcaggag gactataaac ataccatggt agatttagca 18720 actgagtttt cgcatcgatt aaaagcagcg cttagcaatc ctagggagat gtctcaacaa 18780 attggattgc taagttatat tgatattgaa gactaccttt taaaatcttg tgaaaaaact 18840 agaggaaata cggctgaaat atctaatttg gggtatttta gctttcccgc cgattcgtcg 18900 gtaaaaatca agaatatggc atttgcacaa ccttgttcca gtctttctgc accttttgta 18960 ctaaatgtta taacagtagc agatggtcca tgttcgtttt ccctctctat ttttgatgat 19020 gggaacaccg aacaaactca tgagctggct ataaaaataa gggataagtt tctaagtatt 19080 ctcgaaaagg tttctatgaa ttcatagccg ttcccagtat aaaatatcat cgactaatag 19140 gtttgtttat ttttttacct atttttatcc attcttctcc tatttataga tttcaaattg 19200 agaacaggtt attcgaaaga atttttgaat tatgaaaagt ttgaagcttt atacgcactt 19260 tttattaagg taatgctggt taattcaaag atttcgaact tttcttgaat agacacctat 19320 attattcact ttcgaaagtc ttcttattaa caacaaagag catgtagtaa aaatttttta 19380 aataccataa atacttttga gtagctgaac actataagta ttgttatcca caggttgagt 19440 gagtacgaga ataataccaa gacaactaca ctcctttgcc aaccgcgact tagattttca 19500 cttccaccat tagcggatta aactcaacca ttcgcttgtg gtctaagggg atgttaaaaa 19560 gacctaaaag agatcctttg aaagattgtg aatacgtttt taaaggcgac gggctacggc 19620 gagtccctcc ctactattat gaatacatta ccttcgcgaa gctgaggtgg tacggtaaaa 19680 ctcttttaga ggttttcaat accgaattta gggacaggga atctggttat tatgaaaagg 19740 caatacgcaa tggtcaagtt aaggtaaaca atcagattgg taacgttgac acattgattg 19800 aaaatggata catagtttcc catcatgcgc atcgtcatga accaccagtt tctgaccaac 19860 cagtaggcat agtccatgaa gatgaatctt atgttgttat tgacaaacct gctggtgttc 19920 cagtgcatcc tacaggtcgc tataatcaca atactgtttt acatattttg atgaaagaaa 19980 acaaatgttc tctgttatat ccttgcaata gattagacag attaacttct ggtctgatgt 20040 tctttagtaa gagtcctaaa gccgctgaag aaatgcgcgt ccatatgatt agcaaaagcc 20100 tgaaaaaaga atatgttgct agagtaatag gagagttccc caattctggt gaagtaattt 20160 gcgatgctcc gttacttact gttgcaccta ctttaggttt aaataggatc catccggatg 20220 gaaaggaggc cagcaccgtt ttcaaaagaa ttgcgtttga tggacacaca tccctcgtgc 20280 tttgtaaacc actgaccgga aggactcacc aattacgggt tcatctacag tatcttggtt 20340 atcctattgc taatgatcct atatacgcga ataaaagggt atggggtcct tctttaggga 20400 agaatggaga aggcagcaat gaatctgtaa ttatgcgact ttccgaaatc ggtaaaactg 20460 aaactgcttc tccactcttg caatatgagt ggtatacaaa tgaaacagag gcagaggcca 20520 aggcccgtag agacaaacgc ctcggggagc tattaactgg taaacactgt tccgagtgcg 20580 gtactccact ttatagtgat ccatccccag aggaattagg aatctggtta catgctttaa 20640 aatatgagag caaagattgg tcttataaga cacagcttcc aaaatgggct cttgacgttt 20700 gctgccgaga tcctaatgcg ctgcctatag aataaagtaa aagttttgag attatataca 20760 caaaaaattt tgagggttta gggttactca aaaaaatcga atttttaaat cgtcgataaa 20820 atccaatagg tgattgatat atgtatacaa aatagctaaa gtagtttttt tctgacgctt 20880 tgttaacttt ttatcgtttt tttttttgtg agaatagaga tcaaaaagtt aatgagacaa 20940 gtaactaaac tcttcatgtt tgggagtttc tagatactgt tctatgtgct gtcattagac 21000 attacagaag aatctggttt tcgaactctt tcaattaaag aagaaacggt attggcgtca 21060 tttgaacgta ccataagctg tgggtgctaa agtgtttgca tttccatctt tatgtgcatc 21120 ataagttcaa ccatgactta acttctaaaa agacgttcat tctaatacat atttgttaca 21180 cttatgatta tacgactcac aaaagaaaaa tctatttcaa gtaattgatg ggcgttcatg 21240 gtttgctacc tatcattaga aaggtcgcgt ctgagggtat aagatggctt caaccagaat 21300 ttttttctaa atattatcct gttctagcag tagatggaaa tcttttatta tacagatttt 21360 ttcggtctcc aaatacgcca ttgcacacca attatcaaca tgttttatgg gccttaaaac 21420 tatcaaggta ttgtcgcaaa ctaaaaactt cgccaattgt ggtatttgac aacctaaaac 21480 ctaatgattt caaagcagag gaacacgaga aacgatcttt gataagttct caaatagtca 21540 atcagcgaca agttgttcag gaacagatgt attttttatg caatttaaaa aattgtttaa 21600 tagataataa ttttccgact ggtaactttt actacgagat cggtccatta ttatctcaaa 21660 ttggaaagtt gttatttgat ttgcgttctc taaatgaacg tgataatcct tttcatgcac 21720 aaaataatgc cgaaaatcta gagaatgcaa cttttgtaag gttaatcgtt gacaaattaa 21780 atgacaggga aaaaactttg atgatccaag aaaagaaaaa tcatctcata cattctttac 21840 gacaactact tgcgttttca gaaatcaatg acttcccatc tgagatacga tcttacctcg 21900 aatttatctt gtctaatttg gatctggaat gcttgacttt atgtcttaaa atcataaagg 21960 gtattcttac cttagacgaa cttcaaaaag caataaaatt gaaacaaact gaattagata 22020 aattagaaag aaggctatat cgtccttctc ctcaaaacat ttttgaaatt tttgaaatat 22080 taaaaatatt agggatacct gcttcattct ctcctatcgg agtagaagct gaagcatttg 22140 cctcagctat ttctcaaaac aacctggcat atgcagttgc tactcaagat actgatgtct 22200 tactgttggg ttcttcaatg atatctaact ttcttgactt aaatgataat tttcatctac 22260 cgttgcaaat tatggatcct agaaaaattg ctcaagaatt gaacttaaca tttgatggat 22320 ttcaagatta ctgtttgatg tgcggaacag atttcacatc tcgaatccca aagattgggc 22380 ctgtaagagc cctgaaattg attagatact acggtaacgc tttcgatgtt ttaaaagctt 22440 taaacgttga ggaaaaatac attatcccaa cagactatat caagaagttt ttgactgcaa 22500 aaaagctatt taccgatttg ccttctaaca atgagctatt cagttttatt cacaatatcc 22560 ctaaagaatt tctacatctt tctgattcga cgtatttaga tttagagaag caggtgcttc 22620 gtatttttaa tgtgcaaatt gaagaattag atgcaaaaac accttggtac tatcactacg 22680 aattggaaaa agatgtcaaa agcacgtacg agtattgaat cattcaatca ttaaaattca 22740 ttcgtgaagc gaagcggcat taaccaaatg attatataac accaatgtac agaaacatac 22800 caacctgaca ctttcttaac agcaacgaaa ttataaattg ataaaag 22847 //