ID SPAC1856 standard; DNA; FUN; 23269 BP. XX AC AL391783; XX SV AL391783.1 XX DT 04-SEP-2000 (Rel. 65, Created) DT 04-SEP-2000 (Rel. 65, Last updated, Version 1) XX DE S.pombe chromosome I cosmid c1856. XX KW centromere; centromeric; tRNA Ala; tRNA Glu; tRNA Ile. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-23269 RA Saunders D., Harris D., Wood V., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (31-AUG-2000) to the EMBL/GenBank/DDBJ databases. RL ac.uk XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1856 is overlapped at the 5' end by plasmid p7G5, CC EMBL entry SPAP7G5, accession number AL353014. XX FH Key Location/Qualifiers FH FT source 1..23269 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1856" FT /map="ICEN" FT misc_feature 1..96 FT /note="nominal overlap with SPAP7G5 S. pombe chromosome 1" FT misc_feature 1..9032 FT /note="chromosome I centromeric repeat region" FT misc_feature 9033..22100 FT tRNA complement(9438..9511) FT /note="tRNA Ala anticodon AGC, Cove score 67.24" FT tRNA complement(9864..9935) FT /note="tRNA Glu anticodon CTC, Cove score 74.15" FT tRNA 12720..12793 FT /note="tRNA Ile anticodon AAT, Cove score 66.44" FT tRNA complement(18340..18413) FT /note="tRNA Ile anticodon AAT, Cove score 66.44" FT tRNA 21198..21269 FT /note="tRNA Glu anticodon CTC, Cove score 74.15" FT tRNA 21622..21695 FT /note="tRNA Ala anticodon AGC, Cove score 67.24" FT misc_feature 22101..23269 FT /note="chromosome I centromeric repeat region" XX SQ Sequence 23269 BP; 8257 A; 3515 C; 3450 G; 8047 T; 0 other; ttattgaatc tggtgatttg cgtcggaagg ttgagaatat aaagagcgtg tgaaactaag 60 ccatgtaatc taaaacttta ccgaaacttt cagatctcgc ctatttaccg atccaattgc 120 tagtgcagta atagttgctt gaattttcac cggatgaatc ttctcttgaa taaaaccgcc 180 aataagagct agtcaagttg actactgaaa atatacgata ttgaagatgg cgtatgtagt 240 gcttgtaatg gtctggtgga tggtggaagc tttccactct tacttagcat tcagtattac 300 acaaatggat taaggagaag cggtaaacga ttttatgagg ttcgtttatt ataatgggtt 360 gagtgacacg attcaaattg agtcaaaata tttttcgaag ataatccgcc aattttctgt 420 aactcatata ttaatgcatt cgttcaaatg atattaatac atacgtgtaa ataagggaca 480 aataggtata aaaaacacgg cgataagaaa tggaattaat attttgcaac atgacaacta 540 gacattattt cgtccgtaaa ctttaatagt ccacgacaac aaagcgacaa tagcagtcgt 600 ttattatttg gtcttcatta tgtcaacaag ctatttgaag ggatttatgt aaagtatgta 660 tttactttgg aagaatgata gtgataataa taataataat atattttttt attctcctac 720 aactatttca tatcgtcaat cttcaaattt ttcaacatga ttggataatg attacttata 780 aaaaatatat atatatatat atatatatat atacattcat tatatacatt atatacatta 840 tacttgaaca ccccaattgg ctatataatt agagtcagta ttttgctaaa cttttatatc 900 gcgaacatca gcattacttg tatacttact aaaaattcat aaacaatttg gtaattaatc 960 attgaaaata ataaagttaa tgctttgtat atacattcta acagtctaaa gtagagattg 1020 gaagagaaaa agttaaagat tgaatgagtg tttagtcaaa ttgatcgaca ttattgaaaa 1080 ccaagagaaa tcgatcgagc taaataacat tgagcacttg aataattata atttagacgg 1140 aaaaataaat agtttccgaa caacatggag acatatgtcc ttgacttttt aatctgagaa 1200 atgttcaaat agattaaacc tctagtatat ccttaccatg atagccaaaa ataaatccaa 1260 tcaaatttat cattctgaat aattgggatc gcaatttttg attgaggctt tttgccttag 1320 tatatttagt aacaaaaatg tcctttcttg gatttttata accaaagaga atatgttttt 1380 atatcgggct aatcctaata gggagttatt ataataaggg atatatatat ttgaaatgtt 1440 atgctaatca tacgttcggt aggtatgagt gaaatcttcc ttctatttcc ttttaagtat 1500 tagttgagtc ttcttttgat atttcagttt caggttcgca attttaggcc attggcaagg 1560 cgagcgattt gaacatatgc attcgattca tcgattccgt agaaaattga cgatcaaatc 1620 ggtcagtacg ttagttgcag tgtagtatga cagcatgata acatgacatt attaaatgtt 1680 gcaatggaaa tgtacaataa caaagtaagt acaaacatat attttttttt attaaacaat 1740 tattatagtt aaaagaatga taaatgatgt ttataataat tcgtctcccc aaaacaaaca 1800 aacaaactaa tgtttgtttc tagattctaa tatttaccct aacacaatgt actgtagaat 1860 taaatcaatt tcattctttg ctcaacgtag ttaatcaagt aaaattcatt aactgatgac 1920 caggaacaaa tcaggaaacc gagttttttt ggcatctttt ctattatatg tatattgatt 1980 gtctattgta tatatatata taacttcgct gtataatact aatcataaga ggcaatggga 2040 atggttgacg tcacatctac gacatgaatg gaagaatata atctttgtta taacggtaat 2100 aataaacttg atcagtttat gactaatttt ttgctactct atttctctgt ctacgtacgc 2160 cagttgctca tacttactat atctttagtt aaagtatgtg gcataacaat tgagtaaata 2220 aaaataaaaa aaataaacac tttttaaata tggtacttga tttataaaca cacatgttta 2280 agtatatgta catatacaaa ccaacgaaat gtaataatac atccaagtga taagaatgca 2340 aaaacttatt caacagcaga tacaccgttt cttctgttta taacagcata acgtaacata 2400 tagaattgga gacaatataa ggtcttgttg agttgttata cctttcgagg taataatggt 2460 tgattggaag agctagagtt ctgcggtaaa cccatattcc taaatcaagc tttaaccatc 2520 gaaaaagtat gagtcgcaga agtgattttt aaatcaaatt aggctgtaat taaataatat 2580 tatacaaata ccatgaaggc tatccatttt gaaaaaacat attcaatgtc tagattttac 2640 gattttcctt cctcaaatca agcgtaggaa atttacattc cgtaacttga cggttccata 2700 atgatgcaag attccatata cgtaatacta cgtttccatc ggtaacttta aaaacttact 2760 acatttttat ttccttagca tttaaatagt cgttgtcaac cgcacttcct tttcgactcg 2820 tttctttaac gtagcatgaa gaatcctcac attcgacatg actgataaaa gctgatgata 2880 ctgtttttgc tccttaaaat ctatccgtag aaaaataatg cgctttgagt aagaaaacta 2940 tacagaagct gcatctaaaa aacccgaata tcttaattga ctattgtaaa agtgttagtt 3000 tacagatttt tggtaacgag ataagcaacg gagcatgcat atgattacct aagtataact 3060 tgtacacaat gattaggtgg tttgtaaaaa tgaatcctta aagaatgcta caaagaagta 3120 actcaaaatt ccaaccatac tatgctaata gaaacgtgag gcagaaatag aaataatggg 3180 attattggga tagttgaaaa aatgctggag ttaaactgag tctccacaag tatttacata 3240 aacattcctt tcgaagtatt tcattcatct tgcgtgtctg cacacactac tatcatacag 3300 tttcttctcc caaacacaat caaattaaag aacggttcca taagcagtag aatcaaagtt 3360 tcgaaaagat acggccaata acaaagtcag ctttgatttt tatcaccgat tgctgtaatt 3420 tgtaactggc acaacacaat tttcgaaatt ggattgttta tgaataagct atcgtgcttt 3480 tcgtataact tagtgtatct tagcttcctt tgggctataa tcattgtctc tggcttttca 3540 tcttgtagtc tttctcaatc gccggttcca ttttcttcaa tcttctattc aattggatcc 3600 tattctcatc cggaatgctt ttcttccacg gaaaacaaat taccgaattt gtaaactgtg 3660 acgatttttt tttatttatt caaaactttg caaattaaac taccaccaag tctcttaata 3720 agtaaggaag tcgctattat tggattagta gacccacatc accaaaattt cttgccatga 3780 cgacatcacg tgtactagag caattcgggt catacttcgt gttcaattct gatttgattt 3840 cttttttttc gagtatgatt gtcaacaaaa aacgataaag acttttacat ctccagtcgg 3900 ctgaactcca gtaattaaag ttcgatattg tttaaaaatt aaaaaaacaa acaaacaaac 3960 aaaaagatga aatgatgaaa tgattgatga cgattttaaa aaagatcaaa acttgaaact 4020 catatcacaa gaaatggaga caacattcaa ctataaagtt tttcagcgag acatgtaccg 4080 attgattcgg tctttgcagg actcttgatg tttgcctaat cgggttaaat tgtggtggtg 4140 tggtaatacg tactagctct cgtttcttta tatccaactg acggcatcgc ttgtactttt 4200 ttaataactt ctttttcctc ttcgtatggt gtgtaaactg aatggaaacg atgaacccat 4260 catgaacctc acatcatttg gttccgtcta tttagtgctc acccagtgtt gctttatgaa 4320 atgaaacaat ggttgatgtt ttcatcaatc acccatgaat tagtttgggg taaatatgat 4380 tctattatta tctctttctc aaagtgctaa gcgatgatgt acatgtatct atgttttcca 4440 aaatctttat ctcaattttt gaaacaggac ttttaatagt ctttcatatc agcaattgtt 4500 tcagaaaatg ttaacaacca tcaatattta cacaaatgat ataaacactg attttaccaa 4560 gattaccagc gataaaatga gtaaattaag ctctttagaa gtctgatggt aattgataaa 4620 tatcgtgtgg aaagtatacc gaagtttgga agaacaagaa ctttgaagga tgaattttcc 4680 gaaatgtctt tggtatttgt aattttacta catatatttt attaacagca ttttgaaatt 4740 tttcaaaaac ttatttcctt gtctttgtag ctcagtcacc attacttcac taagctattt 4800 gagaattata tgtttattat aaatactcat gaatctttcc caagcaaact taccttgatc 4860 taataattct aaccattcgc atccattttt atttatttaa cttttcattt catatctatc 4920 ttgtttggtt tgtgataaac tcttttttgg aaatacattg ggtttaaact ctgatttgta 4980 aatttatttt tatttttatt cttatttatt ttgtcacatc tttatttgag tgttcatacg 5040 acatttggaa aaacggtgca attgagcaag gctgaattac ttatttttac atttattgac 5100 cactttcatt gaagctaagc tatataatga atgcaacggt tatgtgagat tgagtaagaa 5160 gtgttatgga ataagcaaag ttaaatcagt agctttaatt ttttgttgtt tttaatttta 5220 atttgcaaac aaacaaacaa aaacgtattc atatcataca cctaatattc attcttttta 5280 ttaaaaaaga aaaaaataag cactagtaaa cttgattggt tctatttatt tgaatgaaag 5340 taaacttcgt tattgaaaca cgaataggaa tatcagacaa catatacgag tgtcaagaat 5400 aaagaagagt ttttagattt aaagcagttt taaatgaaaa aactcccata aaatgattaa 5460 atcacattca ttgcaatagg aaactgtatt cggtatatac aatcggtatt gcatgttgta 5520 ccaagtataa tatagtgatg agattttgaa gtttgtgttc tattaccaca tggaactacg 5580 tcaggagtgg agaccataat cgttgtaagt atgttgacaa actttatcca aagggtaaaa 5640 actcagttct tcgagttata aatcggacca gagttgccgc aattgaaacg aattagataa 5700 gtgaacaggg catgcttagc aagtacaaac cagtataatt agaattgaat taacaaaggt 5760 aaaacttgaa cgttcatgtt tgtatactca aaagaatcaa cggagttgtg aaattttctt 5820 agtggagttt actcattgat tttttaccac ttacacacat aagtcttata cttgccaagt 5880 tgaatggtac cattagtacc agtactagtg tcatctagtg tcagtactag tgtcagtata 5940 ggcatcaaca tcatcaccag tatcggcgcc agcatcagca cagcaccact accactacca 6000 cttccactta ccacttccac ttaccacttc cattactacc acgactacca ctaaccatca 6060 ccactttcat ctccattctt gtcattattg gcttgttgta cgttgttcaa atgtttcaac 6120 gtatgtacat ttgtgactac gatttcttgt tagcgatata aacgaagagg ataaagactt 6180 tggagtaaat aattttggcc gtgccactag cataatgtat ttgtgcgtct aggtatcctg 6240 cgtctcggta tccttagcgt tgcaagtgga aagtggcttc acactataaa tggttgacac 6300 agctaataca ttagacataa actttctcag cattcacgaa cagtaaaaat actattggta 6360 aatgattcat ggatatatag tattagtatt tggcattcgt ttcgcttatg aattgtgatt 6420 gaaccgatat cgtatcatca ttaaaagttt cctgtacatc ttctacatca ttcaaacatg 6480 tggaagaatc ataaatttca caaaaataat gtctcaatcg catacgtatt gtctgctctg 6540 acttggcttg tcttctgtat gtgatccaaa tagacgagaa tgtcaatcca tcatgtacga 6600 ccaatcacac ttcctatagc tgaaaccgag tgcaaatgct tttgtagcaa tcatgatctg 6660 tgcctttcca agttaggggt tccaagactc gtcaaagtga atttttcatt cttcttcatt 6720 taaatctctc gtgtaaatgg ttatcaagat gtgatgagag aacaagtcag ggtggtcgaa 6780 aaggatgctt aattaatgta cggtgaacgt ttcatgttta ttcattgaat cacctttcca 6840 aagtctatta ttttgttttt atcaacattc gaaaattcaa gggaaagctt aaatctcttc 6900 taagaataca tgcagaaaca agaaaaatgg tttcccgccc agtggatgct tctgtgaata 6960 cacaaaagtt ttgtatgaaa ggttaaagcg gttgtttggc actgaatgta actaccaagg 7020 aaaaagtaat gctaagcaaa tttaatgatg catatataat tgggacaatt gcaacatttg 7080 caatgttttg ccaaagcgaa attgtatctt tcgtttgcgt ataaggaatg tgcctcgtca 7140 aattatcatc catcccagct gaacaaatac tgtcaaagat ttcaaaaaat accgtgaagc 7200 atttgcttta ttaacgatgt tactcaataa aaagatattc atttgtggca taacaagttc 7260 tcaattcgat tccaagtaca tggagagcgt atgttgaaat taataaatct aaaatggtga 7320 ttaaggaagg attactgtgc atctttgaaa gtcattcaat tccttaatta aaaacgacca 7380 atatgctgcg gttcaccctt aacatcatgt ttttaaccaa cgacatcatg ggtagtaaaa 7440 taagtaaaac catattcata ttctttctta attttctcaa ttttgatcgt atttcgtttt 7500 tttccacaac accagatatt aaaatcgata aagaactttt tccatccgca gttgggagta 7560 catcattcct acttcgatat acttttgaaa gagaaaagtg aaccgattgg aattgtttcg 7620 acaacacgaa ttttacttct aggtcatata tttatggcga tgccaaacaa caatattgtt 7680 gagacagtaa gttaagcaaa tggctaaata aatccaagac tgttgttgag tgctgtggat 7740 ctcaatatta tcagtatcta ctcttctcga tgatcctgta aatttttgtt atcttttttt 7800 atttgcagtt actgataata ctagcatttt gcatgctttt ttttatttgg atgttcttcc 7860 aattgatcaa tacagtaact ttagaactat catcgctatg cctttaaatg accgcactaa 7920 aagcatggta ccaaagctcg aacatagaaa gaaatccaga aagggattta aagattgact 7980 ttttcgacaa acttcatgtt acaagtctta tcgtttgtgt ttataaatca tcagcctctc 8040 tctatatctc tatatctcta tatatcagat ataaagatgc gagttttgaa gtagacattc 8100 cgcacaaagt ctagtacacc atgtctcttg tgctcaggct ggttgtcctg caaaaatgta 8160 caacaggcaa atggatgttt catcaaagat ggactccttt gcctcatact tattgatggc 8220 gaagctagat ccgttatcat cttgagaaaa cacatcatcg tcgtactaca ttttttttct 8280 tactcattgc ttgtttatct actacgatta aactattaca aaggatatcc aggaagatga 8340 tacacaatga aaaccgatat gtgggttgca aaagataagc agtcaccgca agatagagta 8400 ggatgggttt agatgttttc agtaccctaa tgcggagtaa ggctaatcac ggtatttgta 8460 attccatatt ataagaataa aaagtatcgc aacgatttga actgtcaata tccatccatt 8520 ctgtccaaaa tagtatcctt gtatttgaga ggatgattta gttatgcttc tcaaaaacta 8580 aagcaattat agattggtgt ttatgatttc caaatatgcg ttagaaaatg atttttgtca 8640 atgttatttt aaaacaaaag agcatggtgg tggttatgga gtttaacaaa caagaaaaat 8700 gaacataatg tcacatttcg tcctccttta aaagtgtaaa aaatcgaata ctattctcaa 8760 cttaagtagt cattaaatat agatgatatc gaggctttcg gtttagtcgc caaattttac 8820 tttgcgcagt ctctcgtcta tgttgctttt tttttggagg tgtttttact ttttaaattt 8880 caaatttatg aaatttaggc gtgaatattg atgttttgag attttattgt gggcacaaat 8940 atttatggac ttttacttaa taacttttca aaacatacac gagaatttaa cagaagggac 9000 agaaatcgtt tatgaattat cgttttgaga ttatgaacgc ttgcatcact agtatgttgt 9060 tttactatca ttcagaaaat caccggagca atgtttatat atatatatgt ttaatgtatc 9120 agttaattta ctttttttat gacttattac atagtagttc tatataacaa acaaaccatg 9180 gtgtttttta agttaaaatt tattttctta aacgtaaccg atacataatt taggcaaaaa 9240 ttgttgattg attaagactc aatgtaattt agaagctgtt ttaaaaatta cgaatttaag 9300 catataatca ggtcattcgt tgtaccaact gctaagcata attgtatttg gataaagaat 9360 gtatttattg aattgtaaga tggcaaacac attaattctc atgaatttag agatttcaaa 9420 aaaattgata aaaaatttgg acaagccaga actcgaatct gggacctctt ccatgctaag 9480 gaagcgtgat aaccatctac accacatgcc ctaattgttt attttagcgt aagaatatta 9540 taatatatac attaataact tgattttaga ctcaatatta atattttttg aagcttttag 9600 atgaacgcaa atcaaaactt atgttctagc caacgaaaga acatacttga aatttatagt 9660 cccattagat gcatgtattc ataaattttt tcttttcggt tttagtcagg ccagctacgc 9720 tactcatctg tttcgtgttg aaacactagt attatatctt tttttttttc atacgttcaa 9780 taaaatattt tttcttaaaa aaaaaaaaaa aaaagagatt actttatata aagacaaacg 9840 ttaaaaataa attaataaaa cttctccgtc agggggaatc gaacccccgc cgcatcggtg 9900 agagcgatga atcctagcca ctggaccatg acggatgctt agttcacaca atgtttatat 9960 gtatttaacg tatatttaat taaataaaca atttttttat aagctacttt ttattttgaa 10020 attaatagtt attgaaaggc tgcgataatt tataaaacaa aatgtaattt gcaatcaatg 10080 cttaatagta agtcgaattg agatgtaaac gttaaattat gaatagccta taattagaca 10140 atttattaac cccattcaat tagtgaaact acttttaata acactgtcaa aaaccttgcc 10200 ttctgttcaa gatatagact tctctatttt tacatcatta ttctacccta gtcagaacat 10260 atacctatca tatacttttt tcgctcatat tcgttgaatc tttatataaa tagtgtctga 10320 acaataatca taaaactttc tatgctaaca cttactaata ttctctactt gtttttacta 10380 gcgaaaactt ttgatggaga gttacgaggt aaaatgtcct ataaccacca aagtttcgtt 10440 ttctagttac atgatgagat aatgcttcca aacctgattt actgggaaga aaaaccaaaa 10500 ccaaaacaat tgcttagcca taattactat tccggctatt ttctttaggt tttggtagaa 10560 acattggtta acctcatata agtatttaac caatttttct tctggacaaa gtacaaagtc 10620 gttatgtgca tgctatattg gtattgctta caaataagag aatagtaaac taacactttt 10680 cacatttttc taagatacta tgacatattc tcatttttta tattacaatt ataaaatgtc 10740 tggtagaaat agagcttatg gaaaaaatgt ttgaatcatt acaaactttt cgtttttact 10800 gtgttcatta agcataataa aaagattctt tgaaagtgga agaaatcatg aagtaaaatt 10860 ctattttttc tgtacacaga ttctcattca attttttgga ctgtcgcttt caaaggaaat 10920 attttattta atatgagctg gcaatgcttt tacagcaaca attccctcaa caaatatgta 10980 ctatatcaaa actgtatatt tgcaactagt tataaaaatc acaacgtact agttgttgta 11040 ttgataattt ggtaaatcgt tcttgcctag cgaaatattg gttgcacact gtaattagta 11100 cattttctta catttagtaa agcttggtat acaaaattaa tagagcaggt gtatacttga 11160 aagagcttga cacgttttat tattttctca aatttttagt gctacactca aagatatata 11220 caataaagaa tgagtgagtg agtacaagaa gctgaaacat acaaaaaaac aaggtaattc 11280 tcctgagaat gttacgaaag ctaaactact cattgggtat aattgtaggc tttttcacat 11340 atataaatgc tgtttgtaaa ttaaaagctt ttatttattt tatctgtttt ggtataaatt 11400 caagcacata ccaaaaagtc tggcttatat gaatactatc cataatttgg ttaatttttt 11460 ttcaaattta atttattcct aaatttatta gatgatttta tataatagtg atttaagtga 11520 aattttgatc ctttactgga aaattgtcga tattactacg tgagtagctt agtttcttat 11580 aattgcaacg tagataatta taaacaaaga tatacacaga aagttcagtt taaatccaaa 11640 tctacacaat tacaattttt gtaaaaaaag ctttttcaaa cagatactta gcctcagcag 11700 gaaaattatt gatctttgat gtaaaaaacg aatatcgtga aatttgcttg tttagtgttt 11760 gaacgaaaag ttgaatagtt agttataaag cgtatagaaa aaaaaaagag taagcacatg 11820 aagaaacaat attttgtaca ctttgtgact acacaaactg tttttgttca acgattttta 11880 aaacctttaa ataataattt catcttgttt tacaatttcc gcttacaaaa tgccacaaat 11940 caacagcctt cacattttca gtagcagaaa ttgttaaatt caaattttaa atattactat 12000 taaaacactg aacgtctttc aggctttgct gttgagaaat ctgttataaa cagcaagtat 12060 taagttttaa tgcctttttc ttccaaaaac aagtcaagcg gtgacaaatt ttaattgtta 12120 gttaaaaagc aattttaacg attgaatatg cagtacaata tcatagtctc tttatagtca 12180 attgttttta tttaattaaa ctgttttaaa aattcgaaaa tctaagtata ctttcatctg 12240 taatcattga attctcagtt tcaaaaaaat aaaaaaaaca gatagaaatt tgactatgct 12300 ttccatttta gaaaaaaaag gtgtagtttt tataaatcct atgcggttga gtgtaggaaa 12360 ataataaaag taaaaagaca taagtgttta ttatagcaat taccaaattt taataacttt 12420 gatgatgata aagtttatgt gctatcagta atcacatccg atgaacatta ctcagttttc 12480 agtgcaaatt tgtattgcgc atcaagtatt ttgcgacatt gtggcgtaaa aaaaatatca 12540 aaaatcggtt taaagtaaaa ttttcaaaaa agtgtatttc gcatttaatg tctaataaaa 12600 cgaagtactt accattgtaa tcaaaagtat ggcaagagtg gtgtccatcg aaaatataaa 12660 caacagttta ttttaaattt gtacataaat atgttaaacc aaaaaagatt aacaaaaatg 12720 gtcgcatgat gtagtcggtt atcatgtcga tctaataagt cgaatgtcgc cggttcgaac 12780 ccggctgtga ccaaatcttt tttcttttat acttttttat taaaacacga atattgcata 12840 tgaaaataat attcaattca taaaataaat acttgcttta tcatagtatt ttaggcaatg 12900 tcacaaagtt tcaatttgat atttttcttc caaattcatc aatgtgataa aacaaagatc 12960 cacatagcta ttatgaatag cggaatgctt tcttctactg agctaacgag gctaacccac 13020 taaatttgat ataaaaagct cttttgactt taggataaac caattatact agccctaaga 13080 acgaaaaacc tcaaaaaaag gctaccagca ttgttattca taaccacaaa tcaacgattt 13140 ctcagaataa gcttggactt agtataaagc tattaaacac ataaagatta ttcacgtacg 13200 tatttttatg agtgcaagaa tacatatatc ctagttaatt atcaaatata gactttgtaa 13260 gaaaatttgc gttttcttag taaaaacctg atacttatta gcaaccttct ctgttattta 13320 acttggtagt accactttaa cataccaagt attagtcgcc agaaagtcca ttaataaacc 13380 ctatacaaac attaagtaaa ttatttaaaa ttttgttcat atttaacgtt tgacaaattt 13440 ggtaatgtaa tcatgctata ttgtttatca aaaagactta tgatttcaat aatagtttta 13500 taatttaggc aaatagtaga gcgctgagaa tttacaaatt tgaaatatag gaatgatact 13560 ttacaattgt actgctggtg acgccccgta tttgtgtgtt aaaaaaacct catcgagaag 13620 gaaattgttt gatttatgcg aattcaactc tgtttattaa atttaggtaa aaaacgttta 13680 cttttctcac cttctggagt tctttggacc tactatattg caagtcaaag ttggtattag 13740 ttcatcgtcc tccgtttggc aggaaggccg tttctttatg gttaacatat ccgtagttta 13800 taactaaata agaccagtta agcggtatta tcacgtaact tttactgtat ttattgaata 13860 tagctttcaa aaatgtggat gactgattgt ccgataaccc tgcataaaat gaccgaacac 13920 tcacgtcccg gttagtttac atatatcgta ctgttcattc tgaaattttt tcatgcttta 13980 tattactgtg taataaaatt ccataaacca caattcctcc tgtattatga ataaagatac 14040 gaaatttaaa ttcaactaca cgttgtaaaa catatttaat tcatgaacta aaagtaatca 14100 atacttgata aaattggatt taattagaaa agtttgacag agtatatgtc aattcataac 14160 gataaacaat aaacacgaat gcctctttca ttttactaaa attaaaaaaa ggccggctca 14220 tttatagtat taatcaacga agaaatttat atatcacaac cataaagccg tattctaaac 14280 attgtttaat aaatttgatt taaaggttta attaaaggga tttcaatcgc cttgaaatgc 14340 tataacaaaa ctttcatatg tttaacaacg gggttaaaca aatctttttg aagtcatcat 14400 ttacttttta ttttttcgta tggtaaaaaa catttaccct ttttaacatt cagcaagttt 14460 tattgatttc ttatgaacca gaattttcca gacaatcgca tggtactatc aaaacatata 14520 aaaaatgaat gttataacgt ctagtaagaa atacttaaaa aggagcagaa tcttcaaaaa 14580 aaatgttcat gaaatacaca ccactcactt acgcttcacc tagtttccaa aaacatggaa 14640 tgtttgtctt agcaaaaaag gaaatgaatt tgattttccc attaaccgaa atagaaacgt 14700 agaaataaaa atgaatccaa aagtcgcaca cattcttgaa ttaaagaaat taaccagagt 14760 tttcgaatcc gcatggaaaa tacgaatgta atctaattaa caacaaccta atgagataat 14820 tctataaata gagaaatttg caaaatttaa caattctggc tttaagaaaa ataaaatcac 14880 tgcataaatg gaatactgtt gaaataaaaa cagcagttat agagaaatta gtcaagtact 14940 gttcacttaa gtattcaacc gttgcaactt acatcagcat actggaaaat aattctctgt 15000 aacaggaatt ttttaaaact aaatagcatc tcattgctat ttggcgaccg gcggcgttat 15060 aaactaagca attgaccatc tttcgtaaaa tattaaaaaa aaaaaataaa aataaacttt 15120 cgttatacat agaaaaccaa aagaagtgta aagtaacaga tatgtttcgc aatataattc 15180 atagtgtgga tacttttagt catttgcata tataactaaa agaacttcag aaggtattag 15240 tggtcggttt tctttttgtt ggtaatgtct gaagcatttc gccgaaggaa acgccatgga 15300 gtacacgcat aaaacaacaa ccactgaaag cgaatctgta ttgttctggt tctgtactac 15360 ttttgttggt tatacttgat ataaagcaca gcaaacttac agaattgatt aattaaacta 15420 aaagccaaat acattttata ttgtataaag actttcttaa cgcaatagag tcataatatt 15480 tattttcgcc ggtaacaaaa ggatcaaatt aataaaggaa aaggtttcaa cgaaaaataa 15540 ataaaactaa acgttgagct aattaaacac ttatttacat gattatgctg aaatacgcca 15600 taatttaaac taaaagtaca ccgcaaagat cgaacgagtt gtctaatgca atggttacaa 15660 aatgaattgt cgaatatatt tttattactc gaaagtaact tacgtgattt caaaaaaatt 15720 tgtgaacaac ctaaaaacaa atattcctta actcatcatg cattaaacgt ttgtaaaata 15780 tcattagccc gtttatggaa tttcaaaagt ttctccattg tagtttgcta accttttttc 15840 tacaattaac aacatacatt acaagttgga gaagtataaa cagcaaaaat gtacaagcgt 15900 atttcactag aggcttatga atcttaatat ttctgtattt ttgcttaaaa tcgccatttg 15960 tttttatttt tgtcatataa agatagctta agtaatgaaa tatctattga acaaaatagt 16020 aagcgttagt gtcaacttca atccatgaat caaaagataa accagtatca atagcagaaa 16080 taaacaactg ttagcgaaac catgtgagca tgtaaaataa tttatagaaa caccaataat 16140 ttatttctaa caagattgtt ttatctatta tttatattac gacagtcaaa actcatttaa 16200 caatttaagt aaaaaaagat ctcctagaat gttaaaaatt gtaaacaata tcaggaacga 16260 aaagagcaag cagccttaat tacatgctaa gactaaatga gtagtaagca ttgaattgtt 16320 ttgaaacatg agcaaagttt atttgtaaga atttcacgta gcatttcaat actgcaattt 16380 caagtttcaa agaaaaaaaa tatatatggt ctcgttaact tcagcagctt tgaaatatgt 16440 aaattttgta ttgtagtttc taaattactt cgaacgaata attaaagctt tctattgttt 16500 tataaaactc aacaagtatt tttttttact ctttaaaccg gtacgagaat ttttgattta 16560 tttatttatt ttgtttcatt gttacaccgt aaatgataat ttcaacccgt agtttcattc 16620 gtttatgatg gatgaaatcc caaattaatt agagtattat cgtaactatc cgaaagtagt 16680 cggaattaga aagattgatg attgtatgaa ccttttgaat aaattttagg tagaacaaca 16740 ttaaaataag gtcaagacta gacaaaatta attgcttaaa tactttcaaa cacgtctaca 16800 aagctttgat ttgaacatgc acaatccata agtatgaaga ataaaaaatt taaacataaa 16860 taataaataa accaaatcca acactttgat tgttattatt attcaaaatt aaaaaaaaga 16920 aagaccttga acgattaaaa ataaatacac ctctataaaa accaatccat ttaagtcgtc 16980 tgataattag atttaaagaa aagaaaattg ttataattta gtgcgccaaa ttcatatgtt 17040 ttttacaata ttgtaaaaat atatcgatga aagaaaagca tttgatttga attattacat 17100 ctgagatttc caaatgtaca gtgataatgg gtaatgatga cagcgtataa caaatataca 17160 caaaatagtt gcgaaacata gcctcttacg tctttattta atgtagttag ttttgccttt 17220 atccaaaaga agtgtttttt ggtaatttac ttaaaaagta tagattgaaa tactctggcc 17280 atttgctaag ttcgactcaa cataaataca aacaaatcta catttcccta gcaaatattg 17340 atatgttcaa acttagttgt taaatttcct gtttgataaa tactagctta gcaaattgag 17400 tgttttgcca cattaccctt gtaccaaaaa attttgaaca acttttacaa aaaaaaacaa 17460 gaataactgt tgtatagtag ttgcaaacaa cgttgcacca caaaagcaaa aaaggtaaca 17520 caatcaatcc attgatgata ataaaacttc aagagtattc cactacgata caaatactga 17580 cgccaaagat ttatttgcaa aaaagtcaat tgcagaactg ctttttaaat tataaaacta 17640 ttattgaaat cataagtctt tttgataaac aatatagcat gattacatta ccaaatttgt 17700 caaacgttaa atatgaacaa aattttaaat aatttactta atgtttgtat agggtttatt 17760 aatggacttt ctggcgacta atacttggta tgttaaagtg gtactaccaa gttaaataac 17820 agagaaggtt gctaataagt atcaggtttt tactaagaaa acgcaaattt tcttacaaag 17880 tctatatttg ataattaact aggatatatg tattcttgca ctcataaaaa tacgtacgtg 17940 aataatcttt atgtgtttaa tagctttata ctaagtccaa gcttattctg agaaatcgtt 18000 gatttgtggt tatgaataac aatgctggta gccttttttt gaggtttttc gttcttaggg 18060 ctagtataat tggtttatcc taaagtcaaa agagcttttt atatcaaatt tagtgggtta 18120 gcctcgttag ctcagtagaa gaaagcattc cgctattcat aatagctatg tggatctttg 18180 ttttatcaca ttgatgaatt tggaagaaaa atatcaaatt gaaactttgt gacattgcct 18240 aaaatactat gataaagcaa gtatttattt tatgaattga atattatttt catatgcaat 18300 attcgtgttt taataaaaaa gtataaaaga aaaaagattt ggtcacagcc gggttcgaac 18360 cggcgacatt cgacttatta gatcgacatg ataaccgact acatcatgcg accatttttg 18420 ttaatctttt ttggtttaac atatttatgt acaaatttaa aataaactgt tgtttatatt 18480 ttcgatggac accactcttg ccatactttt gattacaatg gtaagtactt cgttttatta 18540 gacattaaat gcgaaataca cttttttgaa aattttactt taaaccgatt tttgatattt 18600 tttttacgcc acaatgtcgc aaaatacttg atgcgcaata caaatttgca ctgaaaactg 18660 agtaatgttc atcggatgtg attactgata gcacataaac tttatcatca tcaaagttat 18720 taaaatttgg taattgctat aataaacact tatgtctttt tacttttatt attttcctac 18780 actcaaccgc ataggattta taaaaactac accttttttt tctaaaatgg aaagcatagt 18840 caaatttcta tctgtttttt ttattttttt gaaactgaga attcaatgat tacagatgaa 18900 agtatactta gattttcgaa tttttaaaac agtttaatta aataaaaaca attgactata 18960 aagagactat gatattgtac tgcatattca atcgttaaaa ttgcttttta actaacaatt 19020 aaaatttgtc accgcttgac ttgtttttgg aagaaaaagg cattaaaact taatacttgc 19080 tgtttataac agatttctca acagcaaagc ctgaaagacg ttcagtgttt taatagtaat 19140 atttaaaatt tgaatttaac aatttctgct actgaaaatg tgaaggctgt tgatttgtgg 19200 cattttgtaa gcggaaattg taaaacaaga tgaaattatt atttaaaggt tttaaaaatc 19260 gttgaacaaa aacagtttgt gtagtcacaa agtgtacaaa atattgtttc ttcatgtgct 19320 tactcttttt tttttctata cgctttataa ctaactattc aacttttcgt tcaaacacta 19380 aacaagcaaa tttcacgata ttcgtttttt acatcaaaga tcaataattt tcctgctgag 19440 gctaagtatc tgtttgaaaa agcttttttt acaaaaattg taattgtgta gatttggatt 19500 taaactgaac tttctgtgta tatctttgtt tataattatc tacgttgcaa ttataagaaa 19560 ctaagctact cacgtagtaa tatcgacaat tttccagtaa aggatcaaaa tttcacttaa 19620 atcactatta tataaaatca tctaataaat ttaggaataa attaaatttg aaaaaaaatt 19680 aaccaaatta tggatagtat tcatataagc cagacttttt ggtatgtgct tgaatttata 19740 ccaaaacaga taaaataaat aaaagctttt aatttacaaa cagcatttat atatgtgaaa 19800 aagcctacaa ttatacccaa tgagtagttt agctttcgta acattctcag gagaattacc 19860 ttgttttttt gtatgtttca gcttcttgta ctcactcact cattctttat tgtatatatc 19920 tttgagtgta gcactaaaaa tttgagaaaa taataaaacg tgtcaagctc tttcaagtat 19980 acacctgctc tattaatttt gtataccaag ctttactaaa tgtaagaaaa tgtactaatt 20040 acagtgtgca accaatattt cgctaggcaa gaacgattta ccaaattatc aatacaacaa 20100 ctagtacgtt gtgattttta taactagttg caaatataca gttttgatat agtacatatt 20160 tgttgaggga attgttgctg taaaagcatt gccagctcat attaaataaa atatttcctt 20220 tgaaagcgac agtccaaaaa attgaatgag aatctgtgta cagaaaaaat agaattttac 20280 ttcatgattt cttccacttt caaagaatct ttttattatg cttaatgaac acagtaaaaa 20340 cgaaaagttt gtaatgattc aaacattttt tccataagct ctatttctac cagacatttt 20400 ataattgtaa tataaaaaat gagaatatgt catagtatct tagaaaaatg tgaaaagtgt 20460 tagtttacta ttctcttatt tgtaagcaat accaatatag catgcacata acgactttgt 20520 actttgtcca gaagaaaaat tggttaaata cttatatgag gttaaccaat gtttctacca 20580 aaacctaaag aaaatagccg gaatagtaat tatggctaag caattgtttt ggttttggtt 20640 tttcttccca gtaaatcagg tttggaagca ttatctcatc atgtaactag aaaacgaaac 20700 tttggtggtt ataggacatt ttacctcgta actctccatc aaaagttttc gctagtaaaa 20760 acaagtagag aatattagta agtgttagca tagaaagttt tatgattatt gttcagacac 20820 tatttatata aagattcaac gaatatgagc gaaaaaagta tatgataggt atatgttctg 20880 actagggtag aataatgatg taaaaataga gaagtctata tcttgaacag aaggcaaggt 20940 ttttgacagt gttattaaaa gtagtttcac taattgaatg gggttaataa attgtctaat 21000 tataggctat tcataattta acgtttacat ctcaattcga cttactatta agcattgatt 21060 gcaaattaca ttttgtttta taaattatcg cagcctttca ataactatta atttcaaaat 21120 aaaaagtagc ttataaaaaa attgtttatt taattaaata tacgttaaat acatataaac 21180 attgtgtgaa ctaagcatcc gtcatggtcc agtggctagg attcatcgct ctcaccgatg 21240 cggcgggggt tcgattcccc ctgacggaga agttttatta atttattttt aacgtttgtc 21300 tttatataaa gtaatctctt tttttttttt ttttttaaga aaaaatattt tattgaacgt 21360 atgaaaaaaa aaaagatata atactagtgt ttcaacacga aacagatgag tagcgtagct 21420 ggcctgacta aaaccgaaaa gaaaaaattt atgaatacat gcatctaatg ggactataaa 21480 tttcaagtat gttctttcgt tggctagaac ataagttttg atttgcgttc atctaaaagc 21540 ttcaaaaaat attaatattg agtctaaaat caagttatta atgtatatat tataatattc 21600 ttacgctaaa ataaacaatt agggcatgtg gtgtagatgg ttatcacgct tccttagcat 21660 ggaagaggtc ccagattcga gttctggctt gtccaaattt tttatcaatt tttttgaaat 21720 ctctaaattc atgagaatta atgtgtttgc catcttacaa ttcaataaat acattcttta 21780 tccaaataca attatgctta gcagttggta caacgaatga cctgattata tgcttaaatt 21840 cgtaattttt aaaacagctt ctaaattaca ttgagtctta atcaatcaac aatttttgcc 21900 taaattatat atcggttacg tttaagaaaa taaattttaa cttaaaaaac accatggttt 21960 gtttgttata tagaactact atgtaataag tcataaaaaa agtaaattaa ctgatacatt 22020 aaacatatat atatataaac attgctccgg tgattttctg aatgatagta aaacaacata 22080 ctagtgatgc aagcgttcat aatctcaaaa cgataattca taaacgattt ctgtcccttc 22140 tgttaaattc tcgtgtatgt tttgaaaagt tattaagtaa aagtccataa atatttgtgc 22200 ccacaataaa atctcaaaac atcaatattc acgcctaaat ttcataaatt tgaaatttaa 22260 aaagtaaaaa cacctccaaa aaaaaagcaa catagacgag agactgcgca aagtaaaatt 22320 tggcgactaa accgaaagcc tcgatatcat ctatatttaa tgactactta agttgagaat 22380 agtattcgat tttttacact tttaaaggag gacgaaatgt gacattatgt tcatttttct 22440 tgtttgttaa actccataac caccaccatg ctcttttgtt ttaaaataac attgacaaaa 22500 atcattttct aacgcatatt tggaaatcat aaacaccaat ctataattgc tttagttttt 22560 gagaagcata actaaatcat cctctcaaat acaaggatac tattttggac agaatggatg 22620 gatattgaca gttcaaatcg ttgcgatact ttttattctt ataatatgga attacaaata 22680 ccgtgattag ccttactccg cattagggta ctgaaaacat ctaaacccat cctactctat 22740 cttgcggtga ctgcttatct tttgcaaccc acatatcggt tttcattgtg tatcatcctc 22800 ctggatatcc tttgtaatag tttaatcgta gtagataaac aagcaatgag taagaaaaaa 22860 aatgtagtac gacgatgatg tgttttctca agatgataac ggatctagct tcgccatcaa 22920 taagtatgag gcaaaggagt ccatctttga tgaaacatcc atttgcctgt tgtacatttt 22980 tgcaggacaa ccagcctgag cacaagagac atggtgtact agactttgtg cggaatgtct 23040 acttcaaaac tcgcatcttt atatctgata tatagagata tagagatata gagagaggct 23100 gatgatttat aaacacaaac gataagactt gtaacatgaa gtttatcgaa aaagtcaatc 23160 tttaaattcc tttctgaacc tctctgttat gtcagtgctt cggtaccatg cttttagtgc 23220 ggtcatttaa aggcatagcg atgatagttc taaagttact gtattgatc 23269 //