ID SPAC17G8 standard; DNA; FUN; 26689 BP. XX AC Z69795; XX SV Z69795.1 XX DT 28-FEB-1996 (Rel. 46, Created) DT 16-JUN-1999 (Rel. 60, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c17G8. XX KW arp2/3 complex; dihydroxy-acid dehydratase; dma1; IUNH-family; KW MYST-family acetyltransferase; pck1; protein kinase; sur1-like; KW transcription factor; transcriptional repressor; tRNA ligase; KW UPF0016-family. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26689 RA Devlin K., Churcher C.M., Barrell B.G., Rajandream M.A., Walsh S.V.; RT ; RL Submitted (27-FEB-1996) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; P36582; P36582. DR GOA; Q10313; Q10313. DR GOA; Q10314; Q10314. DR GOA; Q10315; Q10315. DR GOA; Q10318; Q10318. DR GOA; Q10319; Q10319. DR GOA; Q10320; Q10320. DR GOA; Q10322; Q10322. DR GOA; Q10323; Q10323. DR SWISS-PROT; P36582; PCK1_SCHPO. DR SWISS-PROT; Q10313; YD61_SCHPO. DR SWISS-PROT; Q10314; YD62_SCHPO. DR SWISS-PROT; Q10315; YD63_SCHPO. DR SWISS-PROT; Q10316; AR16_SCHPO. DR SWISS-PROT; Q10317; YD65_SCHPO. DR SWISS-PROT; Q10318; ILV3_SCHPO. DR SWISS-PROT; Q10319; YD67_SCHPO. DR SWISS-PROT; Q10320; YD68_SCHPO. DR SWISS-PROT; Q10321; YD69_SCHPO. DR SWISS-PROT; Q10322; DMA1_SCHPO. DR SWISS-PROT; Q10323; YD6B_SCHPO. DR SWISS-PROT; Q10324; YD6C_SCHPO. DR SWISS-PROT; Q10325; YD6D_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S.pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c17G8 is overlapped at the 5' end by cosmid c6C3 CC and at the 3' end by cosmid c22H10. XX FH Key Location/Qualifiers FH FT source 1..26689 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c17G8" FT /map="IL" FT misc_feature 1..109 FT /note="nominal overlap with cosmid SPAC6C3 S.pombe FT chromosome 1" FT CDS complement(2..115) FT /db_xref="GOA:Q10313" FT /db_xref="SWISS-PROT:Q10313" FT /label=spac6c3.09c or spac17g8.01c FT /note="SPAC17G8.01c, len:38, overlaps and extends orf FT SPAC6C3.09c which has similarity to tRNA ligase, no met FT initiation codon near 5' end in this frame and splicing FT uncertain" FT /partial FT /gene="SPAC17G8.01c" FT /gene="spac6c3.09c" FT /product="putative tRNA ligase" FT /protein_id="CAA93684.1" FT /translation="TRDQRVCIFGEKKSTVRSVTFKAPKSNYDLTSWRIWEQ" FT CDS 1224..2216 FT /db_xref="GOA:Q10314" FT /db_xref="SWISS-PROT:Q10314" FT /label=SPAC17G8.02 FT /note="SPAC17G8.02, len:330, SIMILARITY:Escherichia coli., FT YBEK_ECOLI, hypothetical 33.8 kd protein in leus-gltl FT intergenic region., (311 aa), fasta scores: opt: 664, FT E():0, (38.2% identity in 314 aa)" FT /gene="SPAC17G8.02" FT /product="putative IUNH-family protein" FT /protein_id="CAA93685.1" FT /translation="MTNTIDSFQKGSALENYNIWIDCDPGHDDVVALTLAACAGHCKIL FT GVSTVHGNTTLEFTTKNALAVMELLNQDVDVHAGAAKPLMRESAFATHIHGTNGLAGIS FT LLPDYPKKKATPDAVFAMYTTISNYPEPVTLVATGPLTNIALLLATYPSVTDNIERFIF FT MGGSTGIGNITSQAEFNVYADPEAARLVLETKSLIGKLFMVPLDVTHKVLLDANIIQLL FT RQHSNPFSSTLVELMTVFQQTYENVYGIRNGVPVHDVCAVALALWPSLWTSRSMYVTVS FT LDSLTLGRTVCDVWSQQNQYPANVHVVLEADVSLFWETFIGVIDRLNYL" FT misc_feature 1269..2207 FT /note="Pfam match to entry PF01156 IU_nuc_hydro, FT Inosine-uridine preferring nucleoside hydrolase," FT CDS complement(2841..3440) FT /db_xref="GOA:Q10315" FT /db_xref="SWISS-PROT:Q10315" FT /label=SPAC17G8.03c FT /note="SPAC17G8.03c, len:199, SIMILARITY:Homo sapiens, FT Q14919, nc2 alpha subunit., (205 aa), fasta scores: opt: FT 376, E():1e-15, (38.8% identity in 165 aa)" FT /gene="SPAC17G8.03c" FT /product="putative transcriptional repressor" FT /protein_id="CAA93686.1" FT /translation="MGDPTNNNDSETKPNPATYWKSRFPVARIKKIMQADQDVGKVAQV FT TPVIMSKALELFMQSIIQESCKQTRLHQAKRVTVSHLKHAVQSVEQFDFLQDIVEKVPD FT APPIKAERKTKRPRARRAANEGEHNESVPAKKVKKNTVKEEEIEKDDESATTETPVKEE FT PTGEETEADHEEKASVDHGNFSDKTTSEASSASGDE" FT CDS join(complement(5534..5679),complement(5417..5489), FT complement(5114..5290),complement(4961..5023)) FT /db_xref="SWISS-PROT:Q10316" FT /label=SPAC17G8.04c FT /note="SPAC17G8.04c, len:152, SIMILARITY:Saccharomyces FT cerevisiae, AR16_YEAST, arp2/3 complex 16 kd subunit, (154 FT aa), fasta scores: opt: 245, E():3.7e-10, (29.4% identity FT in 153 aa)" FT /gene="SPAC17G8.04c" FT /product="putative arp2/3 complex 16 kd subunit" FT /protein_id="CAA93687.1" FT /translation="MTFRTLDVDSITEPVLTEQDIFPIRNETAEQVQAAVSQLIPQARS FT AIQTGNALQGLKTLLSYVPYGNDVQEVRTQYLNAFVDVLSNIRAADIPAFVKECSTEEI FT DNIVNFIYRGLANPQAYNSSVLLNWHEKVVEISGIGCIVRVLNSRPDL" FT misc_feature complement(5024..5040) FT /note="splice branch and acceptor sequence, ctaatacggttttgt FT ag" FT misc_feature complement(5108..5113) FT /note="splice donor sequence, gtaact" FT misc_feature complement(5291..5303) FT /note="splice branch and acceptor sequence, ttaacttttttag" FT misc_feature complement(5411..5416) FT /note="splice donor sequence, gtatgt" FT misc_feature complement(5490..5502) FT /note="splice branch and acceptor sequence, ttaattaaaatag" FT misc_feature complement(5528..5533) FT /note="splice donor sequence, gtatgt" FT CDS join(6817..6880,6950..7428) FT /db_xref="SWISS-PROT:Q10317" FT /label=SPAC17G8.05 FT /note="SPAC17G8.05, len:180," FT /gene="SPAC17G8.05" FT /product="hypothetical protein" FT /protein_id="CAA93688.1" FT /translation="MATFLSPAQDNLVRTYFAQHLKKWVVQYKLYRNAVTPKTLEFLKQ FT NINPSMLACVDEATMIDAEPELEDIIVRTKLWNFRQSFTIEGSIYEVGSFKVAIANVLQ FT KSVWKGILFHVTYDGTESVDLARPIIQEFFLKCFLQNNKSVTPVYESFFNQPRHSLDSK FT LLLQLFKQRIDTVSQRT" FT misc_feature 6881..6886 FT /note="splice donor sequence, gtaagc" FT misc_feature 6933..6949 FT /note="splice branch and acceptor sequence, ctaactttgaatttc FT ag" FT CDS complement(7780..9576) FT /db_xref="GOA:Q10318" FT /db_xref="SWISS-PROT:Q10318" FT /label=SPAC17G8.06c FT /note="SPAC17G8.06c, len:598, SIMILARITY:Saccharomyces FT cerevisiae, ILV3_YEAST, dihydroxy-acid dehydratase FT precursor, (585 aa), fasta scores: opt: 2497, E():0, (64.5% FT identity in 572 aa)" FT /gene="SPAC17G8.06c" FT /product="putative dihydroxy-acid dehydratase precursor" FT /protein_id="CAA93689.1" FT /translation="MMFCKLLRCQNGIASKRAALSLKGFKTSSINLVEKKLNKYSETIT FT GPKSQGASQAMLYATGLNEEDMKKPQVGIASCWYEGNPCNMHLLDLGRRVKEGVKKAGL FT TGFQFNTIGVSDGISMGTTGMRYSLQSREIIADSIETVMQGQWYDANVSIPGCDKNMPG FT CLIAMGRFNRPSIMVYGGSIRAGHSPCQNNAPIDIVSAFQSYGEFITGKIDEPTRHDII FT RHACPGGGACGGMYTANTMASCAEAMGMTLPGSSSYLAGSPEKFAECEAAGSAIKRLLV FT DDIKPRDIMTRSAFENAMVLTMTLGGSTNSVLHLIAIAKSVGITLTLDDFQAVSNRTPF FT IADMKPSGKYVMEDLFAIGGIPSVLKYLHAEGLIDGSNITVTGKTLAENLRGFKDLAEG FT QKIIRPLSNPIKTEGHLRVLRGSLAPEGSVAKITGKEGLNFTGKARVFDAENDFIAALE FT RGEFKKGEKTVVIIRFEGPKGGPGMPEMLKPSSAIMGAGLGKDVALLTDGRFSGGSHGF FT LIGHVDPEAQVGGPIALVQDGDVIEINAVKNTLDLMVDEKEMARRRSVWKAPPLKYQQG FT TLLKYARNVSTASKGAVTDSLE" FT misc_feature complement(7915..9282) FT /note="Pfam match to entry PF00920 ILVD_EDD, Dehydratase FT family," FT misc_feature complement(8035..8070) FT /note="PS00887 Dihydroxy-acid and 6-phosphogluconate dehydr FT atases signature 2" FT misc_feature complement(9076..9108) FT /note="PS00886 Dihydroxy-acid and 6-phosphogluconate dehydr FT atases signature 1" FT CDS 10810..11463 FT /db_xref="GOA:Q10319" FT /db_xref="SWISS-PROT:Q10319" FT /label=SPAC17G8.07 FT /note="SPAC17G8.07, len:217, SIMILARITY:Saccharomyces FT cerevisiae, YNK7_YEAST, hypothetical 26.0 kd protein in FT cyb5-leu4 intergenic region., (226 aa), fasta scores: opt: FT 576, E():3.2e-31, (44.9% identity in 225 aa)" FT /gene="SPAC17G8.07" FT /product="putative transcription factor" FT /protein_id="CAA93690.1" FT /translation="MAPNTRVSKCQISRPILVGNDAKPLTKEEKEKAPTDHTHTWRIFV FT EGVDGEDISKWVRKVVFKLHDTYNNPTRTIESPPFEVIETGWGEFDIMVRIFFAPEAHE FT KALTFYHHLKLHPYGPRMEEMKASGGLVESVQYEEIVFNEPFEYTYKLLSQNPIGDGHG FT LAVESEPDHPFSQQLEQDEADKLDFAIQEVKKTIEMYKQQVQSLQGQKSSTPVE" FT CDS join(complement(12835..12891),complement(11757..12563)) FT /db_xref="GOA:Q10320" FT /db_xref="SWISS-PROT:Q10320" FT /label=SPAC17G8.08c FT /note="SPAC17G8.08c, len:287, SIMILARITY:Saccharomyces FT cerevisiae, YB37_YEAST, hypothetical 30.3 kd protein in FT mba1-rps9b intergenic region., (280 aa), fasta scores: opt: FT 545, E():1.4e-28, (32.9% identity in 286 aa)" FT /gene="SPAC17G8.08c" FT /product="hypothetical UPF0016-family protein" FT /protein_id="CAA93691.1" FT /translation="MKNPIKWAIIAVLLSTVVAKKIVGEGMADVSAIKHPEEVHPTNRD FT FLRSLIFSISMIFGCEIGDKTFIVAALLAFENSRLTVFAGSYSALFIMTLLGVLLGHAA FT PLLFPRKLTDILGGVLFVIFGIKMLMEAKEVMDSKESMSDEFQNVRNEIAANGPIDQLL FT EEGAAPSHYTGHRSRSGHTLMSQLKSKGRNVMATLFSPLFIKAFALTFVSEWGDRSQIA FT TIAMAASDNVYGVFMGANVGHACCTALAVISGKYISTKIKVHKVMFIGGILFIAFGLVY FT FYQGFF" FT misc_feature complement(12031..12756) FT /note="Pfam match to entry PF01169 UPF0016, Uncharacterized FT protein family UPF0016," FT misc_feature complement(12564..12578) FT /note="splice branch and acceptor sequence, ctaacactactttag FT " FT misc_feature complement(12829..12834) FT /note="splice donor sequence, gtaagt" FT CDS join(13770..13877,13985..14106,14172..14340) FT /db_xref="SWISS-PROT:Q10321" FT /label=SPAC17G8.09 FT /note="SPAC17G8.09, len:132," FT /gene="SPAC17G8.09" FT /product="hypothetical protein" FT /protein_id="CAA93692.1" FT /translation="MDRDVTLNVDELVSKFKKEGHFDRLRKQILETVNEKESGPLLDRL FT KKIIDEEMVKDRTLKSKDQFRAAPLIAGAVDRSSLYEDSMEHIRSNVLSDQDLREVIYN FT SLEQIGIEQIEHEDEEKLLNSKTMDGRK" FT misc_feature 13878..13883 FT /note="splice donor sequence, gtaggg" FT misc_feature 13970..13984 FT /note="splice branch and acceptor sequence, ctaacatcgcctcag FT " FT misc_feature 14107..14112 FT /note="splice donor sequence, gtaagc" FT misc_feature 14160..14171 FT /note="splice branch and acceptor sequence, ctaacccataag" FT CDS complement(14979..15782) FT /db_xref="GOA:Q10322" FT /db_xref="SWISS-PROT:Q10322" FT /label=dma1 or spac17g8.10c FT /note="SPAC17G8.10c, len:267" FT /gene="SPAC17G8.10c" FT /gene="dma1" FT /product="dma1 protein." FT /protein_id="CAA93693.1" FT /translation="MTKSVEGYLKEQELAAETDSEKDDDKISIRLTNFVGPNAHSFSFD FT PLVRYWNRKQNNLPIYIGRYTERYNGGDVSAIVFRSKVVSRRHAQIFYENNTWYIQDMG FT SSSGTFLNHVRLSPPSKTSKPYPISNNDILQLGADYRGGHEVNYRCVRARVELNNSWKI FT KLSPYNLNEFKRMQELVLCGSSESGPPECCICLMPVLPCQALFVAPCSHSYHYKCIRPT FT LNESHPYFSCFICRKYHDLEAPVEEGDESLNDLLRNATVKDDASE" FT misc_feature complement(15372..15542) FT /note="Pfam match to entry PF00498 FHA, Forkhead-associated FT (FHA) domain," FT CDS complement(16852..17922) FT /db_xref="GOA:Q10323" FT /db_xref="SWISS-PROT:Q10323" FT /label=SPAC17G8.11c FT /note="SPAC17G8.11c, len:356, SIMILARITY:Saccharomyces FT cerevisiae, YB11_YEAST, hypothetical 44.4 kd protein in FT cdc28-arl1 intergenic region., (376 aa), fasta scores: opt: FT 895, E():0, (42.9% identity in 296 aa)" FT /gene="SPAC17G8.11c" FT /product="hypothetical sur1-like protein" FT /protein_id="CAA93694.1" FT /translation="MNKILFYFFFFLTLILSATVYLFGGPMMLFFINYKTDLLKVDDVY FT NHEIYSNQSAAIPKIIHQTWKTNEIPEKWVGAQKSCIDLHPDYEYVLWTDESMREFIAT FT DYPWFLTQYDSYPYNIERADVVRYFILYKYGGIYLDLDVGCNRTLDPLLHYPAWVRRTS FT PSGISNNVMGFAKGHPFLLQVVRNLPRFAFNYHFPYLTVMYSTGPLFLSIIWSAWRKLP FT DAEAWHHIWVMVPELYEKSHHAFFEIYEGSSWHDSDAGFVFYMLHHWAIFTFLGFLTFF FT IVVYFIFGYALKPAARVSRTGRRVFSSPFSKTSPSRWKIFHRFTSSNEKYDQTRSDSLP FT FMSDYDLESQTQSHSP" FT misc_RNA 18805..19050 FT /note="mRNA not associated with an ORF" FT misc_RNA 19052..19162 FT /note="mRNA not associated with an ORF" FT CDS 19977..21803 FT /db_xref="SWISS-PROT:Q10324" FT /label=SPAC17G8.12 FT /note="SPAC17G8.12, len:608," FT /gene="SPAC17G8.12" FT /product="hypothetical protein" FT /protein_id="CAA93695.1" FT /translation="MASNPNAVEQEILQAVNSAQTTDKRKAHEQSLAYLPVEEERGVNV FT VGSKMKPRYIALTCDDVTRIFYIHRLKVNDKGGMTVVKSWPLFELQNITVINDHDVTMT FT INKPHLLRTQDTSARDRFVFSVAKNYMYYMGRPLSVTTTDGRKVDWAYRNSFADNKPNL FT YPAKSLAIPKARSSLPENSSEQVSSSFNSRVAHNRNFSDGPIVTNLETDQPRIEKKLTI FT DSSRSAKKKLSVEKERRFSDNKPSSNVSRGTPSSAHSDVIEISSSSAIARTSGDRKDDV FT LFDTSTQRRDNQTREMFIQEQAQLFPSKPSLRKTTRREQAPSFNSGTSSSERGKNSISG FT SYEKNTALALEAGKYNMSQKDVKLSSSLESNTFASDFSKVDRDATQAALSSSLETPSVL FT TSSYKPSSSSKVSAKSVSRKPTGAPAIPKLPPKHPSRQPTVRATPSTGKQIEPPNDEPS FT IGNELLPLFESLRFENRKTTSKPKAKKTLVTSIPTKPHQASVEKVYDLNSKINLKNIPE FT QSISRLSTLKWNEGTTIKDVLKQTEFSFDGAIISSVENLAEEEIELQNIKSQLQDCALG FT CESINSTINLFSLELSTALNGVINIEQQPSRR" FT misc_feature 21636..21665 FT /note="PS00422 Granins signature 1" FT CDS join(complement(22790..23242),complement(22584..22673), FT complement(21856..22536)) FT /db_xref="SWISS-PROT:Q10325" FT /label=SPAC17G8.13c FT /note="SPAC17G8.13c, len:407, SIMILARITY:Homo sapiens, FT AAC99368, histone acetyltransferase., (611 aa), fasta FT scores: opt: 1005, E():0, (55.4% identity in 280 aa)" FT /gene="SPAC17G8.13c" FT /product="putative MYST-family acetyltransferase" FT /protein_id="CAA93696.1" FT /translation="MPATILKSTASSKTLLIIKFDTNSSRYPFYKKHLLELNSESTFLG FT LLTKGQADTSITRLNQDDVRLFEKAKTVADRTKDVAYSFSDPILSTQLRTPPPQPTSIR FT YLYFGTYRIKPWYTSPYPEEYSCAKNLYICESCLKYMNSDHVLQRHKMKCSWSYPPGDE FT IYRDKNISIFEVDGQRQPIYCQNLCLLAKMFLHSKMLYYDVEPFLFYVLTEFDGQECKV FT IGYFSKEKRSASDYNVSCILTLPIYQRRGYGVFLIDFSYLLTQVEGKLGSPEKPLSDLG FT LVTYRSYWKMRVAKALLEITTPISINAIAKSTSMVCDDVISTLESLSVFKYDPLKKKYV FT LQLKRDELENVYKAWNIKHPQRVNPKLLRWTPYLGEEQISNLLLKENILIPLPQKRLLD FT NSHHLDSV" FT misc_feature complement(22537..22553) FT /note="splice branch and acceptor sequence, ttgatgtttttcctt FT ag" FT intron complement(22537..22583) FT /note="confirmed intron by BLAST homology" FT misc_feature complement(22578..22583) FT /note="splice donor sequence, gtaagt" FT misc_feature complement(22674..22686) FT /note="splice branch and acceptor sequence, ctaacataatcag" FT intron complement(22674..22789) FT /note="confirmed intron from BLAST homology" FT misc_feature complement(22784..22789) FT /note="splice donor sequence, gtaaac" FT CDS join(complement(24666..26689),complement(24409..24610), FT complement(24176..24364),complement(23951..24134), FT complement(23814..23905)) FT /db_xref="GOA:P36582" FT /db_xref="SWISS-PROT:P36582" FT /label=pck1 or spac22h10.01c or spac17g8.14c FT /note="SPAC17G8.14c, len:896" FT /partial FT /gene="SPAC17G8.14c" FT /gene="pck1" FT /gene="spac22h10.01c" FT /product="protein kinase c-like 1 (EC 2.7.1.-)" FT /protein_id="CAA93697.1" FT /translation="DHLLSYNRSAFDLFNSEKPLSPEKISTMLQHLQMRLSIEQQCVSG FT IEKIMSLYSKEQKDKTDVIIKLKEGKQKVNLLKRSLKRYNELHIPFDISTPSSEEKQQA FT SGLNFRGLAKPISGTLKVTIHSLRNIEHTSFLQTHSFTMPSYAVLYVDDAQVAKSRISQ FT TDTWDETFIFDVHRAKEFQIIIYEKKKDFDIPIALILIPTTIIAEELRRKRNIQEMSET FT SWKPSIAESASRSDEKGSKSDPINAPNSSSSISTNSPLAPTAYYKLLSKSWLSLEPVGQ FT ICISLSFSKRTTKRQFPETGLGRQGAIRQKKEDVVASQVGHQFVQRQFYQIMRCAVCAE FT LFSYSPGLQCENCSFVCHKKCVTKVLASCIAQSNSEKSDFGGLRYRIPHRFEPFNSLGA FT QWCAHCGFFLPLRRKDCFKCVECGITCHGQCAHLIPDYCGMSNDLKHQLLTELEVSKRP FT KKPELPNQENKTTNEKVYRKPLSSQNTFDTLPTISQGLLAATQPVTSVLNTSPLPKTPE FT KDRSLNVTPSSSTPTPASVLAPPSSASLSSSKDANRSVPESPRREKKNRVTLDDFTFLA FT VLGKGNFGKVMLAEYKVNKKFYAIKVLKKEAILKNEELESLKTEKHVFEVANKEKHPFL FT LNLFASFQTSTRVYFVMEYILGGDLMVHIQRQQFSVKRARFYGAEVCLALKYFHENGIA FT YRDLKLDNILLCPDGHIRIADYGLCKENMLLGNTTSTFCGTPEFMAPEILLEQQYSKDV FT DWWAFGVLMYQMLLGQSPFKGEDEEEIFDAILSDEPLFPINMPADAVSLLRGLLTRDPN FT QRLGSGPKDANEVMAHPFFASIVWDDLYNKLYEPSYKPLINDPRDLNNFDEEFTSACPT FT LTPVNTVLTRQQQECFRGFSSFATE" FT misc_feature complement(23906..23920) FT /note="splice branch and acceptor sequence, ctaacgatcgattag FT " FT misc_feature complement(23945..23950) FT /note="splice donor sequence, gtatga" FT misc_feature complement(24002..24196) FT /note="Pfam match to entry PF00433 pkinase_C, Protein FT kinase C terminal domain," FT misc_feature complement(24135..24150) FT /note="splice branch and acceptor sequence, ctaattcaaaaaata FT g" FT misc_feature complement(24170..24175) FT /note="splice donor sequence, gtatgc" FT misc_feature complement(24197..24976) FT /note="Pfam match to entry PF00069 pkinase, Eukaryotic FT protein kinase domain," FT misc_feature complement(24365..24377) FT /note="splice branch and acceptor sequence, ctaacgaaaatag" FT misc_feature complement(24403..24408) FT /note="splice donor sequence, gtaagg" FT misc_feature complement(24520..24558) FT /note="PS00108 Serine/Threonine protein kinases active-site FT signature" FT misc_feature complement(24611..24622) FT /note="splice branch and acceptor sequence, ttaaccccatag" FT misc_feature complement(24660..24665) FT /note="splice donor sequence, gtagta" FT misc_feature complement(24860..24958) FT /note="PS00107 Protein kinases ATP-binding region signature FT " FT misc_feature complement(25376..25486) FT /note="PS00652 TNFR/NGFR family cysteine-rich region signat FT ure" FT misc_feature complement(25376..25525) FT /note="Pfam match to entry PF00130 DAG_PE-bind, Phorbol FT esters/diacylglycerol binding domain (C1 domain)," FT misc_feature complement(25583..25726) FT /note="Pfam match to entry PF00130 DAG_PE-bind, Phorbol FT esters/diacylglycerol binding domain (C1 domain)," FT misc_feature 26553..26689 FT /note="nominal overlap with cosmid SPAC22H10 S.pombe FT chromosome 1" XX SQ Sequence 26689 BP; 8996 A; 4720 C; 4644 G; 8329 T; 0 other; cctgttccca gatcctccaa gaagttaaat cataattaga tttgggagct ttgaatgtaa 60 ctgatctaac agttgatttt ttttctccga atatgcaaac tctttgatca cgagtctaca 120 taattcttga accaaatctt ctgaattatt aaaattcaaa accataattt tttaagaaaa 180 aataataaag caaaagcctt gaattcaacg aacttccttt gactgaatgc tctacagaaa 240 aataagcaac tatgtatttt tggaagaaat caataaagga agaaaaacat aagcttttct 300 cagcagttgg ccggaagaag caactacact gatttgaaaa gagtagagcg aaagacaaaa 360 actaatttat ttctgctcac agttaagctt ggtatatgga agcaacatta gttacggtag 420 attctattat gtctcagtaa aatctattta caaattcaaa aatacctgat aaatcttgat 480 ctactaatta aagcgagcac gtatttattt ctacttatca ataataaacg ggttgttttt 540 tcattgatat aatgttttgt cttctacctt ctgtgcaagc tttaataagt taacaaatta 600 gctgaagtta caaatcttta cttcgtttta gcaatagcat tttcaaaagt aaaaattcca 660 gctgttaaga attccgataa cattttacat atggatgtaa ccaacattat tattcattag 720 caaacaaaaa attcggttag tttttaatca tgctagctgt tgataaatgg tttcaggaat 780 taaacggaaa gtcattgcaa acactaaccg tagcaaataa atttcaaatc ataagtcaaa 840 ataacgtttt tctacgtttt gtgagccact ctcttgcagt gcgttactca aatgtatcca 900 gaacagcgga aaattaaacg aaaattgatg aagatagatt tcaagcgtcg gcatttttga 960 tacattaatt gtctacttac aaggtcggtt gaatagacaa tttccgcatt aggggctact 1020 aggctatcca tctgtgcaat atttattacc atttttaaac cacaacacca catatctctt 1080 tgcaaggtta ttagccatat attttattgt gtcctcgtcc agcaagaata ttatcttcgg 1140 atgtccaaag taataaagtc ataaaaaacc tcatagctag tactaatcga ttttttttta 1200 agcttagtga ttattgtggc accatgacta acacaattga ttcattccaa aaaggctccg 1260 cattagaaaa ctataacata tggatcgatt gcgatcctgg acatgacgat gttgtcgcct 1320 taacattggc tgcttgcgct ggacattgta aaattttggg tgttagtacc gtacatggta 1380 atacaacgct agaatttact accaaaaatg ctttagcggt aatggagctt ttaaatcaag 1440 atgttgatgt tcatgctggc gcagcgaagc ccttgatgcg cgagtccgcg ttcgctactc 1500 acatacatgg tacgaatggg cttgcaggga tttcattgct tcctgattat cccaaaaaga 1560 aggctactcc tgatgcggtg ttcgctatgt ataccactat ttctaattat ccagagcctg 1620 tcactctcgt agctaccggt cctttgacaa acattgcatt gttattggca acgtacccaa 1680 gcgttaccga caacatagaa aggtttatat ttatgggtgg tagcacaggc attggaaata 1740 ttacttctca agcagaattc aacgtgtatg ctgatcctga ggcagctagg ctcgttttag 1800 agactaaatc acttatcggc aaactattta tggtgccgct agatgtcact cataaagtac 1860 ttttagatgc aaacattatt cagttactgc gtcaacatag caacccattt agttccacac 1920 tggtagaatt gatgactgtc tttcaacaaa cttatgaaaa tgtctacgga attcgaaacg 1980 gtgttcccgt tcatgacgtt tgtgctgttg ctttggcgct gtggccatct ctgtggacct 2040 cgcgttctat gtatgtgact gtaagcttag attctctcac tcttggtcgc actgtctgtg 2100 atgtatggtc gcaacaaaat cagtatccgg ctaatgttca tgttgttttg gaagctgatg 2160 tttcattatt ttgggagacg tttattggag ttatagacag gctcaattat ttgtagtata 2220 tttatgacat tatcgactag tgttttatgt ttatttttta caacgatcaa gttctccctt 2280 cattttcaat tttgaaagca cttcaagcat tcatcatgcc ctcttatatc atccattgga 2340 aatacaaaac caaatacttt cttttttact caaagaagta cgtttatact tttgcattgc 2400 atatagtttt ataaaatctt agactataaa aatatcatta tttgaattta aatactaaca 2460 acaaagtatg tataaataaa tgcttaatta taaacaaaag ggtgtacgag taagtgatag 2520 gttcgtagaa ttgtcaatag catcattttg gcaaataaaa tcagtagacg ccaagttggt 2580 ctttcatagt acattaataa ggcactttaa aaaagctcaa tatgaacaac cagaacgtat 2640 tatattctta agtcgaagaa aaggcttaaa aatactagaa ttaatgtgcc aattttatag 2700 tcctatgtac aagtagcttg agaatatttt ctgaaaacaa attcaagaaa aaagggaaga 2760 taagaataaa tgtaatagca aaacaagaat aaagtataca aagacattat atttatggtc 2820 atatagggtg gagaaagtag ctactcatca ccagacgcgg aagaggcttc actagttgtc 2880 ttgtcagaaa aattaccatg atcaacagag gctttctcct cgtgatctgc ttcagtttcc 2940 tcaccagtag gttcttcttt gacaggagtt tctgtggtag ctgattcgtc atctttttca 3000 atttcctctt ctttaacagt attcttttta acttttttag cgggaacact ttcattatgc 3060 tcaccttcat tagctgctcg acgagcacgg gggcgttttg tctttctttc ggctttaatg 3120 ggcggagcat ccggtacttt ttcaacaatg tcttgaagaa aatcaaactg ttcaacactt 3180 tgaacagcat gctttaaatg agaaacggta acacgctttg cttggtgcaa tcgcgtctgt 3240 ttgcacgatt cttgaattat actctgcatg aacaattcca acgctttcga cataataacc 3300 ggagtaactt gagcgacctt tccaacgtcc tggtctgctt gcataatctt ttttatacga 3360 gcaacaggaa atctgctttt ccagtacgta gcaggatttg gtttagtttc actatcatta 3420 ttatttgttg gatcacccat tataagaagc agaattaaca agataattcg atattaaagt 3480 caatagtaag ttggcgtgta aatgattgtt tcggaaatga atcgcttgaa ggagctggta 3540 agtaaggtag taacgaaaac gtatattact acctctattg agactgtctg tcaagttttt 3600 aaaaaaattt tttttctaat ttgtcgaatt tgagaagtta aagtaaaaat cttctagtgc 3660 ctaacagcgg atcttagtat tctttataac aaggtagtgg tgaaggactc gtttaaaagc 3720 agaattttat gtaggtcgcg gaaagcaata attcggaatc acaagcgact aacttccagg 3780 aaatatagca aagaaactcg gtaaatatta atttggtttt cttttagtcg ccatacttgc 3840 caagtatttt gctcaatatt ccaaatgaag gcaatttaga ggttcataat atgcatacaa 3900 tcacagttta aataagaata aaataacaga ttcagatata cgtgtgtaat cagagcaagc 3960 aaaacaaacc agcaaccaaa tttttaaata ctagtaaaaa gtttttcttt tcttaaagta 4020 gtagcgagta aatacatgct tacaaatgaa ctcaaagtat ttaaaagctt tcatgcttaa 4080 gattgctgct aattgatata atattccaac ttgttttgac aacaaagaca cataatttgc 4140 aatgtcagtg ctttaatctt tgtacgtaat aattactttt actaagaaaa tttcaattaa 4200 taatatgaca ttaaatttat aaaaaattga tttgcaatag cacctttgta gaatccttcg 4260 aactaatgac tcaaaaggac tcgcacttta ccttcttcga agacgacaca acgattatca 4320 ctttctatac agagctatcc ttgcaagata tgattactct ctaattttac aaaactaaac 4380 gggattaata tttttttttg caagaaacta cttactatga gctatcctaa agcacgcata 4440 agacgatttt ttcgtcagca ttgccagcgc agccttgaaa gttccgcatt ggatttggta 4500 tggaaagtta taaatgaaac tagctatttc tcagtcagta tctttttgga cgcgctattc 4560 taataaagat attcaaattt tttatattga atgttttcaa ctaacagaat tttcaaggta 4620 tatttggatt actgtctttt cttacaatcc ttactaaaag aagccaatat tgaagcggct 4680 aagactgggg aaagaagagt acagccagaa catgttcgaa gtattcaaag agtaagctaa 4740 tattgaataa actagattta ttatcttttc agcaaaggcg taaatcgatt gcactttatt 4800 ttttaaaatg gaacatactt actaaccatt tagaaaattc tagctcaatt taaaggataa 4860 aaagagtcat tatgtgggaa agaagacata aaacagaatc attgattcag ttccataagc 4920 gacagaatag tagataccaa aaagtaagat aaagccatat ttatagatcg ggtctactat 4980 tgagaacacg aactatacat cctataccgg atatttccac cacctacaaa accgtattag 5040 tgaccgaata aaaatgtaaa gcatgagata agcaatgcta gagcgttggg aaaagcaata 5100 aactaaaagt taccttttcg tgccaattaa gtaatacaga cgagttgtag gcttgaggat 5160 tcgccaatcc acgataaatg aagtttacaa tattatcaat ttcctccgtt gaacattctt 5220 ttacaaatgc gggaatgtca gcagctcgta tattgcttaa tacatcaaca aaagcattca 5280 aatattgagt ctaaaaaagt taaaattcat ttacaccata ataaaatgaa atcaagaaga 5340 attgtaaatt taatcaataa ataaaaacgt aattgatata aaccgtcttt aagcagtttg 5400 tacagtttgc acatacccta acttcttgaa catcatttcc ataaggaaca tatgagagta 5460 aggttttcaa accttgtaag gcatttcctc tattttaatt aataaaaaaa ttgcttcttt 5520 taaataaaca tacgtttgaa tggcagaccg ggcttgagga atgagttgag agacggctgc 5580 ttggacttgc tccgccgttt cgttacgaat tggaaatata tcttgctctg ttaaaacagg 5640 ttctgtgatg gagtcgacat ccaaagtccg aaacgtcatt ttataactct ataactggta 5700 aggtaaagaa aacgatggaa caggttaagt ttcagctgtg tgtagctcta aagaggcatc 5760 atacaacggt cgaacgcaag tctgtaactg aagttattat aattcataga gtatattaat 5820 ttaaccaata agttaagaaa attcaaaaaa atatatttat atttttttaa tcttataact 5880 ttaacttata atttttgagc ggagctatat aagtctggta acagcattac taacttcttc 5940 agtactccat agacctcttt tgtggatgtt tatttttttt tatttgtaaa taatcatctc 6000 tacctttggt cttagatgta aagttctgaa taacttgtag acagaaattg gttacatatt 6060 ttacatttct gcctatggtg attcagaaga aaatatgtta gatacagcct agtaattagt 6120 tgaataaaga ttaaaagtaa tttttttttt gcttctatct attttcagta tgtatattga 6180 tgtatgagtt tatacttcta ttcgaacaat aacttttaag acttattttg ctgacagaac 6240 tatgtagttt cttgtgtaaa gttcaaagta aaacgaagag acacatatgt aacatcctgg 6300 gattaacaga tttttaatta gtgctcaaac cagccagtta cattgttacg tagtatttga 6360 ctctccagaa gttaattatg aatgtaattc agttaactta attctcttca agcttttaac 6420 aatttgctct gggattatca tacccaaaag ccatatactt tgcgacttgg aaaataataa 6480 aaatgacaag agataaatta ataaaatttg agctcatatt atgtctatct gctttttttt 6540 tttaatacag gaacaatgaa aatgaaggtt ttaaattagc ctgttagcaa ttcttgcaac 6600 cgccgtacgc attaaactct tcacatcaac attacagtag aagtaaaaga actaattcgg 6660 ccatttttct caataattcg gtataaaccg atattcagat gcataattaa ttaccattca 6720 tctttgttat aaaatatgcc tgttcacggg taaaaagcat accgattgac tattttgctg 6780 attgattata gagttattta ttattcatcg ccttcaatgg cgacgttcct ttctccagca 6840 caggataatc tggttaggac ctactttgca caacatttaa gtaagctgac actggtttgg 6900 attttatttc ttatgattga tgatttcaag atctaacttt gaatttcaga aaaatgggta 6960 gttcagtata aactttacag aaatgctgtc actccaaaaa ctttagaatt tttgaagcaa 7020 aacattaatc ccagcatgct ggcgtgtgtg gatgaagcga caatgattga tgcagaacct 7080 gaacttgagg acatcattgt gcgaacgaaa ttatggaatt ttcggcagtc ctttactatt 7140 gaaggttcaa tatatgaagt agggagcttt aaagtggcta ttgccaacgt tttacaaaag 7200 tccgtttgga agggtatact ttttcatgta acttacgatg gtactgagtc cgtcgatctc 7260 gcacgcccta ttattcaaga attctttctt aaatgctttt tacaaaataa taaatcggta 7320 acccctgtct atgaaagctt ctttaaccag cctcgtcatt ctttggattc aaaacttcta 7380 ctacagttgt ttaaacaacg cattgatacc gtttcacaac gcacatagaa taaaaaagta 7440 tcaatttaaa ttttttctgt aaataaattt ctatctaact aactgtcaaa gtcttgcttt 7500 attgtcagca gaaagttatg gctccctttc acatttacag ataccaatta tgtttaataa 7560 taaaatagaa atgcaggagt ttgaataaca acccatttta aactcgatgc atttcactgt 7620 actccaaaaa gtaattattc attcaaaatt attcaaataa actctagatg agattatgga 7680 atcagcatta aaagcttatt aatcaacctt tactaccaaa acattaaacg tctaagtttc 7740 caaaatacta tgcgcgctta taaaagcatt gaatatgctt tactctaagg aatctgtaac 7800 agcacccttg gaggcagtgc taacgttgcg agcatatttt aaaagggttc cttgttggta 7860 cttcaaagga ggtgccttcc aaacactgcg gcgtctcgcc atctccttct catcaaccat 7920 caaatctaaa gtgttcttta cagcattgat ttcaatgaca tcgccgtcct gaacaagagc 7980 aatagggcct ccaacttgtg cttcgggatc aacgtgtcca atcaaaaatc cgtgagagcc 8040 accactgaaa cgaccgtcag tcaaaagtgc aacatccttt ccaagaccag ctcccataat 8100 agcacttgaa ggctttaaca tttccggcat accaggtcca ccttttggtc cctcaaaacg 8160 aataatgacg acagtcttct cgcccttctt gaactcacca cgctctaagg cagcaataaa 8220 atcgttttcg gcatcaaaaa cacgagcttt gccggtgaag ttcaagccct ctttgccagt 8280 aatctttgcg acagaacctt caggggctaa agaaccacgg aggacacgta aatgaccctc 8340 ggtcttgatg gggttgctca aaggtctaat gatcttttga ccttcggcaa ggtccttgaa 8400 tcctcgtagg ttctcagcga gagttttacc agtaacggta atattagaac catcgatgag 8460 accttcagca tggagatatt taagtactga aggaatacct ccgatagcga acaaatcttc 8520 cataacgtac ttcccgctag gcttcatatc ggcaataaac ggtgtacggt tactgacggc 8580 ttggaaatca tccaaagtta aagtgatacc aacagactta gcaattgcga tcaaatgaag 8640 aacagagttg gtagagccac caagagtcat cgtcaagacc atagcatttt caaaagcaga 8700 acgtgtcatg atgtcgcgag gtttaatgtc gtcaaccaaa agtcgcttta tagcactacc 8760 tgcagcttcg cattctgcaa acttctcagg tgagccagca aggtaagaag aagaaccggg 8820 taatgtcata cccatagctt cggcacagct agccattgta tttgcagtat acataccacc 8880 acaagcacca cctccaggac atgcatgacg aataatgtca tgacgggttg gctcatcaat 8940 ttttcctgtg ataaattcac cataggattg aaaagcagaa acaatatcga tgggtgcatt 9000 gttctgacaa ggagagtgac cagcacgaat actaccgccg taaaccataa tactagggcg 9060 gttgaatctt cccatagcga ttaaacaacc aggcatgttt ttgtcacagc caggaataga 9120 gacgttggca tcataccatt gaccttgcat gacggtctca atggagtctg caataatctc 9180 acgagattgc aaactataac gcataccagt agtacccata gaaataccat cactaacacc 9240 aatagtatta aactggaatc cggtcaatcc agcctttttg acaccttctt tcactcgtcg 9300 accgagatca agtaaatgca tattgcaagg atttccttca taccaacaac tagcaatgcc 9360 gacttggggt tttttcatgt cctcctcatt aagtccagta gcatataaca tagcttggga 9420 agcaccctga gacttcggac cagtgattgt ttcactatac ttgttcaatt tcttctcgac 9480 taaattgatc gaagaggttt taaagccttt taggcttaat gcagctcttt tgctagcaat 9540 accgttttga caacggagaa gcttgcagaa catcatcttc taaaaaaaaa atttcgcttt 9600 gtttagacta tagaaaattt tctactaagg gtcaactcca ggatttcttc aaattcccct 9660 tttataaata ataataaaca aaggaaaata tgaaagaaca aacttataac aaacttggtg 9720 ttagatttaa atggaatatc tgctggtgac ttaacttatt cacccttggt tagtggtcct 9780 ggtaaagtat gctaaaccgg agatgcgaaa tataaaacac ggtttatatc tcggtaaatc 9840 aaacgaatca agagaaagcc caatcatttc ctaaataaat caatataaaa gtgacatgat 9900 tggatatatg gtatgacaca taaaaatcta tgaatgtaca gatcatggtg atcgtacata 9960 gcaaaaacgt tgttttaact aagaggcgaa ttttcagtaa gaaaaaagca tgactagtat 10020 ttttgtcgct tcatatttca cttttgattg acatagagat gctaagaagc tttgatcttg 10080 cgattatgaa actaaaaatt acaaattttc acatcaccgt agattgattt taagattttt 10140 ctaatttatt tgatttctag caattaatga tacgaaatgt tttattacat ttgaaaaaat 10200 agtcctttga catggctacc tacattaaac catccaacct acccattgaa aagtagatgg 10260 ttgatttttt cattcttaag actttttaaa taaaatatat atgatcagaa ttcaatttta 10320 cagcttatca tttttgacat atcccagaaa aagttagctt actgaacatt ctatttgata 10380 ttttatttct tgttcgaatt tgtattgact gctactggac gaaaagtact caaataacgt 10440 aaattagggt gttgttaaca tgaatacgga attttgcatt ttggtgctta tacagttaga 10500 ctgaaggatc taaaagatga tatgtgtatg tgtcccactt cacttgatgt gaatgcattt 10560 taaaaggtct agtaaatcat tcatgaattt gatttattcg cggtttgtta tttagttttt 10620 tttcttttat ttcgtggttt taaaaaaaaa taaatgctat tttaatactt catggaaact 10680 gtaacgctta taaattgtta caagtgattt atattttcgt tactcactag caaaattatc 10740 ctgaattaaa taataaatct tcactagttc ccatactctt tttattttta cttttgatac 10800 ttagttaaaa tggcacctaa tacacgagtg agcaaatgcc aaatatcaag accaatccta 10860 gttggcaacg atgccaaacc attgaccaaa gaggagaaag agaaggcccc tactgatcac 10920 actcatactt ggcgaatttt tgttgaaggg gtggatggag aagatatttc aaaatgggtt 10980 agaaaggttg ttttcaaatt gcatgatacg tacaacaatc caacacgtac catagagtct 11040 cctccttttg aagtaatcga aactggttgg ggtgaatttg acataatggt acgcattttc 11100 ttcgcccctg aagcacatga aaaagcctta acattttatc accatctaaa gcttcatccc 11160 tacggtcctc gcatggaaga aatgaaggct tctggtggtt tggtcgaatc tgtacagtat 11220 gaagaaattg ttttcaacga accttttgaa tacacgtata aattgctttc tcaaaatcca 11280 atcggagatg gccatggttt agctgttgaa tcagagcccg atcatccatt ttcacagcaa 11340 cttgaacagg atgaagctga taaacttgat tttgccatcc aggaggttaa aaaaactatt 11400 gaaatgtata agcaacaagt tcaatccctc caaggccaaa aaagctccac acctgtcgaa 11460 tagaggcatt attttatata ttataaactg aatatccatg tatgtcttat attttggcta 11520 tagtgctatt atatgtggtt tttttaatgt aaataaaata tatataaata caaatacaga 11580 ttgtcatcta tttaagaaca tgatgattac tggttttatg tagtgattta tgtatcggaa 11640 caaaatgaaa taactaaatg gctctgtagg tgttgtgtta acaaataaca catattataa 11700 aaagattgta ttctatagta tctattattt ctaacggcat agtaatacgt tgtattttaa 11760 aaaaagcctt gataaaaata aaccaatcca aatgcaataa agagtattcc tccaatgaac 11820 atgactttat gaacctttat cttggtagaa atatattttc cagaaataac tgccaaagct 11880 gtacagcaag catgaccaac attagccccc atgaatacac cgtaaacatt atcactagca 11940 gccattgcaa tagtagcgat ttgggagcga tctccccatt cactaacaaa ggtaagtgca 12000 aacgccttta taaataaagg agaaaacagg gtagccataa cgttccgtcc ctttgatttt 12060 aattgcgaca ttaaagtatg tccagagcga gacctgtgac cagtgtagtg ggaaggtgct 12120 gccccttcct ccaacaattg gtcgatgggg ccattagcag ctatttcgtt gcggacgttc 12180 tgaaattcgt cagacatgga ttctttagaa tccataactt ccttcgcttc cataagcatt 12240 ttaattccaa aaatcacaaa aaggacacct cccagaatgt ccgttaactt tctaggaaaa 12300 agtaatggag cggcgtgccc aagaagtact cctaataatg tcatgatgaa tagagctgag 12360 tatgacccag caaaaacagt taatcgagag ttttcaaagg ccaaaagagc agctacgatg 12420 aaagtcttgt ctcctatttc acaaccaaaa atcatagata tagagaagat caaactccta 12480 agaaagtcac ggtttgttgg gtgcacttcc tctggatgtt tgatagctga cacgtctgcc 12540 ataccttcgc caacgatttt tttctaaagt agtgttagat tcaatgcaaa aaaactttga 12600 tttcaattat ctatcaaaac attacttctt ccaaaaggaa aagtgaatat cattgattta 12660 agaatgtaga aaaacgatta tagcaaaatc gtaaattact gagacaaagt aaattctgca 12720 tcacctgcat atttgcacgg aatttatttc gtctttgtac aacaataaac taatcacgat 12780 tgtattgcac aagaaccaat gagacgtgtt ctaaaggaca aggaaaaaac ttacagccac 12840 gacggttgac agcaaaaccg ctataatcgc ccattttatt ggatttttca tgacaatatt 12900 aaaagactgg gatgcaaata gtaattgcaa tgtttgttga gcgtagatgc aaagtttggt 12960 gtagctgaaa ttttaaaggt agttaacaaa ttcttcgacg tattgtgcgc acaccaaaaa 13020 aaagcagtta taattaaatg aattcagaaa aacaaccaca ttttgaaaat aggcctgtgt 13080 ctttggttag tatcggtaaa acattttcat ttattttctg gccttcacgt ggcatatgcc 13140 aaaaacctct aatttgtttt aaaacaggtt tttaactctt atctttcgaa aagttgttat 13200 agttaccact tgactgtata ttaattgatc attagtgggt ataatacaag cattaggact 13260 tgcaaatgct cataatttta tgcctttttt ttactttcat gtattacttg ttgtagcaat 13320 aggaaccaat gccaatcctt ttaattgtaa gtgtaatacg cgaaaccaaa cagaagtttg 13380 ataatttttt agatgggaaa ctcacattgc actacctaca taacgcaagt tcaaccataa 13440 acacataaga aaattcacta gccaaacggt caaagtaaag ccttaacaac agaacatcgc 13500 atttaagtta aacctcgtta gtacgtgttt cttacagggt gattgtacga agtcccttct 13560 gcgagatatt acttcaagaa cttttacatt gagcaatcaa gacacgatca attaattcaa 13620 gttaaatgtg tcttgtaaaa taactcgagt tttattaata aggtagtata aatatggccg 13680 aataatctgt aatcaaatct ttacatttcg tgaaaattct tttctttacc acattatttt 13740 accgtgtagt caattcataa acaaaaggca tggataggga tgtaacactt aatgttgatg 13800 aacttgtatc taaatttaaa aaagaaggac attttgatcg ccttcgaaaa caaattctag 13860 aaacagtaaa tgaaaaggta gggtcatcga tagtttcctc aaaaattaaa ctatcactat 13920 tttttttaac tatcataatg ataccaatgt cactcactct tttgccatac taacatcgcc 13980 tcaggaatca gggcctttat tagatcggct gaaaaaaatc attgatgaag aaatggtgaa 14040 agatcgcaca ctcaaaagta aagaccagtt tagggctgct cctttaattg caggtgccgt 14100 agataggtaa gcttacgact taataatggt tttttttctt ttctttttgg aaactcagtc 14160 taacccataa gatcttcatt gtatgaagat agcatggaac acatccgaag caatgtttta 14220 tctgatcaag atttgaggga agttatttat aattctcttg aacaaatagg gattgaacaa 14280 atagagcatg aggatgaaga aaaattgctg aatagtaaaa ccatggatgg gcgcaaatga 14340 agataattag ctacttaaaa gtttgaaaaa gttttgttat tgattacttc taaattgcat 14400 atactgaaca tacttattac aattaagaat tgtactctcg ggaattttac cagcaatcac 14460 attaggttgc ataagaagtg aattaaaagt tataacattt aatgatgctg aaggagataa 14520 taaatggact ctcagaagaa caaccacaat tctttcagat tcggatctct attactgctg 14580 attattagta cattcatttg tgatgccaat gtttcaaaaa aaataaaaaa atgtgagagt 14640 atgtagagat caggtgtgaa ggacgacaga agttaagatt atatatccat ttaggataat 14700 tatattaatg cagtaatgaa taaaagagac caagtagcac ttggttttct catcaataaa 14760 atatttaatc attatgagtg ttgataaata aagttaggga ggcatgcttg tttaattcaa 14820 tcatcaggca acagcaaatg tcaaagagcc tgtgttccca taatcttctg ccatgctcat 14880 aaagactaaa tataatatga tcattatgtt acgatggtca ttaaaggaag aacttgagga 14940 cgtaaaagac aattagtaac catactgaaa ataacagttt actcagatgc atcgtctttt 15000 accgttgcat ttcgtagaag gtcatttaga ctttcgtcac cttcttcaac aggagcctcc 15060 aaatcatgat attttctaca tataaagcaa ctgaagtatg ggtgactttc gtttagggtt 15120 gggcgtatgc atttatagtg ataagagtga gaacaaggtg caacgaacaa tgcttgacaa 15180 ggtaaaacag gcataagaca tatacaacat tccggaggac ccgattcaga agatccgcat 15240 aacaccagtt cttgcattct tttgaattcg ttaaggttgt aaggactaag cttaattttc 15300 caagagttgt ttagctcaac tcgggcacga acacaacgat agttgacttc atgacctcct 15360 ctataatccg ccccaagttg taatatgtcg ttgttcgaga tgggataagg cttactcgtt 15420 tttgacggcg gtgataaacg aacatggttc aaaaatgtac cagaactaga acccatatct 15480 tgaatgtacc aagtattgtt ttcataaaat atttgtgcat gccttctact cacaactttg 15540 gaacggaaga caatagcaga aacatcaccg ccgttgtatc gctctgtgta tcttcctatg 15600 taaatgggta gattattttg cttgcggttc cagtagcgaa ctaacggatc aaaagagaaa 15660 gaatgtgcat tgggaccgac aaagttagtt aaacgaattg atattttatc gtcgtccttt 15720 tcagaatcag tctcagcggc aagttcctgt tctttgaggt atccctcaac agattttgtc 15780 attttttgga aagaaaagct ttattaaaac aattgaatgg aggatagaaa gttacaaaaa 15840 acaaataaat taatgttaaa agcttttgaa aattgtcttc cgtataccaa tttgatgtta 15900 tccaagaaaa agttcaaaga aatatgcctt ccttctagta aattgaagat aaggtaagtt 15960 tcaaatctat tgctaacaaa atacgaaagt atatggggtt gttgtgttta tgtattaaag 16020 tttggaagca acaagagaca aaaacgaaaa caaaggcctc aaaaacaaac aaactgttga 16080 aagctaagga aggacagcaa acagaactct taactgaatt gcacacttta attccgaaaa 16140 gaaacacttt taataatcaa ccagaattta gctgtaaatg aaaagcaatc gaaaaaatga 16200 tagttttcgc tgttatcaga aaaatatgtt ataaattatg aagccaattt agtagaacaa 16260 gtaaattgca cacagtaaac ggtcaaatgg tgctgcaaac gaatacagtt aatgctatgc 16320 cgcctcgaaa ggcgcatgac taattcggta tccaacttac ggtacaacac aatgttttct 16380 tcggtatagt aattgtgcat taaataaaac aaaacaaata ataaaaacaa ataaaaaact 16440 agatgcgtcg cataaacaat gacgatgatg gtattttgtc tatctttgtc tcaccataca 16500 gatggactta agcaacaccg tttttatgtt gaataattta ttgttttagt ataatttaga 16560 atttagctga aaatccatca aacaaaaagt aagttgaaat gagtagttcc gaaaatatct 16620 ttagcatttc tatttttata gatttggact tgagtcattt catggtatat atccctttcc 16680 gatcacggta gacaattgtg aaattacttg cttttaatag actatattag aaaactagaa 16740 cgaaactaaa tgaaatacaa ggatttatga taattctatg aaaatgaaaa gatagacagg 16800 tcaaaacttc aaagcaaatg aagcctttgt agtagcaaat gccgagtaat tttagggact 16860 gtgactttga gtttgcgatt ccaaatcata atcagacatg aaaggtaaag aatcagaacg 16920 agtttggtca tacttttcat tggaagaagt gaaacgatgg aaaatcttcc aacgggacgg 16980 agatgtctta gaaaacggag atgaaaatac ccgtcgacca gtgcgggaga cacgagcggc 17040 aggcttcaaa gcatagccaa atataaaata tacaacaatg aaaaacgtca aaaaaccaag 17100 aaatgtaaaa atggcccagt gatgcaacat atagaataca aatccagcgt cactatcgtg 17160 ccatgatgaa ccttcataaa tttcaaaaaa tgcatggtgg ctcttttcat acaattcggg 17220 aaccatcacc caaatatgat gccaagcttc ggcatctgga agcttccgcc aagcactcca 17280 tattatcgac aagaacaatg gaccagtcga atacattacg gttaggtaag ggaagtggta 17340 attaaacgcg aatctaggta ggtttctgac cacctgtaaa agaaatggat gccctttagc 17400 aaatcccatt acattattgc taatcccact tggggaagtt ctcctcaccc atgctggata 17460 atgcaataag ggatcaaggg ttcgattaca accaacatcc aaatccaaat atattccacc 17520 gtatttgtaa agaataaagt atcgaacgac atcagcccgt tcaatattgt aaggataaga 17580 atcatattga gtcaaaaacc aaggataatc agtagcaata aactccctca tggattcatc 17640 agtccacaat acatattcat aatcaggatg tagatcaatg caacttttct gggcaccaac 17700 ccatttttcc ggaatttcgt tggttttcca agtctgatgt ataattttag gaatagcagc 17760 agactggttt gaataaattt catgattata aacgtcatca actttaagaa ggtctgtctt 17820 ataattaata aagaacagca tcattggacc tccaaaaaga taaacagtag cggaaagaat 17880 tagtgtcaaa aagaaaaaaa agtaaaaaag tattttgttc atggtggcat caaatatacg 17940 cttccagcga aataaaatca ggtcagttgt atattcgtgc ttggtagatt cagcacacaa 18000 aaagaaattt tgcaataaaa gtattttagt tgaagttaga taatgctaga ttttaacaga 18060 ttctagtaag aggcaagttt ttggttctca ctctttgctt gctttttagg cagtgtaatt 18120 aattggacta agaggaagga aaaaatataa ggtgagataa aacgtatata ctaatgaatc 18180 acttatatta ttaaaaccca gtgaactcga ttccgccaag tagtacaaga taattttggt 18240 cactaaaaga gttgccctgg gacaaaagca atagtagtat aaaatattaa aactgaattg 18300 acgtcggaga aagtcagttt tatattatca aaataaaaaa ctggagaaaa attagtaaac 18360 atccaaattt tggtcaatta tatccttaca aataagaaaa aataaaaaaa ataaataaaa 18420 attattgaaa atgccagtaa tagcagacga caaacttgga ctagacaaga attgtcaatt 18480 ggaggggggg taaaaactaa aacttttaag agattgattt gaagccaaca cttctgagag 18540 agtaattaaa aaaagaagaa aattctgatt ttatagagat aaaaacaatg ctacagtaat 18600 accatccagc tgctgtacaa gttatgcaaa ttgaagaagt atttgggctt ggttgcggaa 18660 agtttagcct tcccaacaaa aaaagccacc aagtcacatg taccctattt gcgattgagc 18720 gcattgacat tttgtaaact gtatggcaaa tacgtaaaga aacaatacac ccaatttgat 18780 ttcatttatt tctttacata ttttggactc aaaaaaaaag taaattgtgc tttgtaagct 18840 gttaatttta gcaaggtacc tcttaaagtc attgctaaaa ggtcctagca aagatgctta 18900 gcttttaaac attttactct tcaagttatt catcgcaaag ccaacgttaa cggcatcctg 18960 atttgtctac tatgaagtta tatgatagaa gtttgcttat ggaggaagcg cgtggtccca 19020 atagcattat atatatgagt atgcaaaaca gctgattttt gtgcaaattc tatcaccatg 19080 gatacaggtc aagatatttt ttacgataac gaagaaataa aatacatagt cttaattgta 19140 ctgttcaaat ctactaggtt ttaactttgg ctgtcgcgaa gtctttggtt cgttcaatgc 19200 tttgattatg ggtctgtaat tgtaccaaac agtgtaataa gaatccctag catgttacta 19260 taaatatcta gtattcgttg caagatgctc attgtgtaac acacttttat aagttctaca 19320 ggatgtggaa atgagcggat aattattgtc ctgcgtagta ctaatactta actatagcta 19380 accattttaa acgttgctgg ttatgcaatt agaattacac tatggctatc aatgtgtttc 19440 ctgtttcaat aatttggatt ttttaagctc gtcgaataaa caaagctgcc ataaagtaca 19500 gcgaagtcat caacaaaaaa gttatggatt attgtacttt tcatgcacag caaaaatatt 19560 taaagatgtt taaatatata taaatattat gaacgtagac aatgcttgca agtttaaata 19620 aactttaaaa aatcgacttc tatagcattt gcctacatat gtcacttgtt tacgttttga 19680 catttctcct tattaaccca ccattccacc acaattgtaa aaattattat caaatttata 19740 tatttcttta ccgctagaat tcaattttac aagaaaattt tatcccttgc ttataaagac 19800 tctgtgaatt aaaaaaaagt ctcgtttcct tagaaaattt gtttttccgt tgaataaggc 19860 gctttcagta ttacttgcca ttggaaagtg gtagaatgtt taattaatgg tttttttttt 19920 gttaatattt atctatttaa cccaattttt ttcatttaat acaccacttc agacgaatgg 19980 cttctaaccc taatgccgtt gaacaagaaa ttctacaagc tgtcaattcg gctcaaacta 20040 ccgataaacg gaaagctcat gagcaatcat tagcatatct tccggtggag gaagaaagag 20100 gagttaatgt tgttggctca aagatgaaac cccgctacat tgctttgact tgtgatgatg 20160 tgactcgtat tttttatata cacagattga aagtaaatga taaaggcgga atgacagtcg 20220 tgaaatcctg gcctttattt gagttgcaga atattactgt aattaatgat catgatgtta 20280 ctatgacaat aaacaagcca catttgttgc gaactcagga cacttctgct cgcgatcgat 20340 ttgttttttc tgttgctaaa aattatatgt actatatggg caggccgctt tcagtgacta 20400 cgactgatgg ccgcaaagtg gactgggcct atcgtaattc ctttgctgat aacaaaccta 20460 atctctatcc tgcaaagagc ctagctattc ctaaagcaag gtcatcatta cctgaaaatt 20520 cttcagaaca agtttcctca tcttttaact ctcgagtcgc acataaccgt aatttttcgg 20580 acggcccaat tgttaccaat ttagaaacgg atcagcctcg catcgagaag aagctcacta 20640 ttgattcttc tcgatcagcc aaaaagaagt tgagtgttga aaaagaaaga cggttttctg 20700 acaataagcc ttcttccaac gtttcccggg ggaccccatc atctgcccat agtgatgtta 20760 tagaaatttc aagttcttct gccattgcaa ggacttcagg agaccgaaaa gatgatgtct 20820 tattcgatac ttcaactcaa agacgagata atcaaacacg ggaaatgttt attcaagaac 20880 aagctcaatt gtttccatct aaaccttctt tacgtaaaac tactcgtcgt gaacaagcac 20940 cctcatttaa cagtggaacg agttcttcgg aaaggggtaa gaatagcatc agtggttctt 21000 acgagaaaaa tacagctttg gcactagaag ctggtaagta taatatgtct caaaaagacg 21060 tgaaactaag ctcttctttg gagtcaaaca catttgctag cgattttagt aaagtggatc 21120 gtgatgctac ccaggcagct ttatcttcta gcttagaaac tccttcagta ttaacgtcat 21180 cttacaagcc ttccagttcg tctaaagtat cagcaaagtc tgtttctcga aaaccaacag 21240 gagcaccggc tattcctaaa ttacctccaa agcacccgtc ccgtcagcca actgttcggg 21300 caactccttc gactggtaaa caaatcgaac caccaaacga cgagccttct ataggaaatg 21360 aacttcttcc cctttttgaa agtttgcgct ttgaaaatag aaaaaccact tccaagccaa 21420 aagccaagaa aactcttgtt acttccattc cgactaaacc gcaccaagct tctgttgaaa 21480 aagtttacga tcttaactca aaaatcaacc tcaaaaacat tccggagcaa agcatttctc 21540 gtctttccac tttgaagtgg aatgaaggta caactataaa agatgtattg aaacaaacag 21600 aattttcgtt tgatggagct atcataagca gtgtggaaaa ccttgctgaa gaagaaatcg 21660 aattgcaaaa cattaagagc caacttcaag attgtgcttt aggttgtgag tctatcaatt 21720 caaccatcaa cttattttcc ctagagttgt ctactgcatt aaatggcgtc attaatatag 21780 agcaacaacc aagccgtaga tgatacaaat gcttcacgac aaatatcgaa agattaaaat 21840 acttatttat ttgaactaaa cggaatccag atgatgagag ttatctaata gacgcttttg 21900 aggtagagga ataagtatat tttctttaag taaaaggtta gatatctgct cttctccgag 21960 atatggcgtc catcttagaa gttttggatt tactctttga gggtgtttga tattccaagc 22020 tttataaaca ttctcaagtt catcccgttt cagttgtaat acatatttct ttttgagcgg 22080 atcatactta aatacagata acgattccaa tgtggatata acatcgtcgc ataccataga 22140 tgttgatttg gcgatagcat ttatgctaat cggtgttgtg atttccaata gagctttggc 22200 tactctcatt ttccaatagc ttcggtacgt aacgaggcct aaatctgaaa gtggcttttc 22260 aggtgatcca agcttacctt ctacctgtgt aagtaaataa ctaaaatcaa tcaaaaagac 22320 accatatcct cggcgttggt aaatgggtaa tgttaatata caggaaacgt tataatcaga 22380 agccgagcgt ttctctttac tgaaatatcc aataactttg cattcttggc catcaaattc 22440 agtcaataca tagaaaagaa acggttcaac gtcatagtac agcatttttg aatgaagaaa 22500 catctttgct agaagacata aattttgaca atatatctaa ggaaaaacat caataagtat 22560 aaaatgcata aaaaattact taccggttgc cgttgaccat caacttcaaa aattgatata 22620 ttcttatccc gatatatttc atctcctggt ggataactcc atgagcattt catctgatta 22680 tgttagtccg taaattcaat ttggatagat tatgatcttt taatgtacac ctcgtttaaa 22740 ctcaagcaat agcgaataac attatgatct tacttgaaaa gttgtttacc ttgtgccttt 22800 gtagtacatg atcactgttc atatacttta aacaagattc gcatatatat aaattttttg 22860 cacagctata ctcctctgga tacggtgatg tataccatgg ttttatccgg taagtaccaa 22920 aatagaggta tcgaatggag gttggttgtg gtggaggcgt tcgcaactgt gtagataaaa 22980 taggatcgga aaatgaataa gccacatcct ttgtcctatc tgctactgtc tttgcttttt 23040 caaacagcct cacatcgtct tggttgagtc tcgtaatcga tgtgtcagct tgccctttag 23100 ttaatagacc caaaaaagta ctttccgaat ttaactctaa taaatgtttc ttataaaatg 23160 gatatctgga ggagtttgta tcaaacttta ttattaacaa agtctttgaa ctggctgtgg 23220 atttcaaaat agtcgccggc attatacata aaaaaaaaag attgtttata tttacagatc 23280 gttcatagtt ttcctaatgg ccccatttaa tcctttggtc aatataattg agttggtggt 23340 agtgccctca ttctcttctt agttcttgct ttacttccac ctccatccga tctctgcaaa 23400 gataaccctt tcactcttgt taaataaaaa actactcata ttttttactt ttgtattctg 23460 aaacagtaac cattcataac ttcactgtta gctttttgat tgaatgccat tacaaacgtt 23520 gcgtataaat actacaaagt caccttgggt gattcaacga taagttttac attagtagtt 23580 ttaatgccac tttaattatt ctctaatttc gactttattt tcaagtaatg taatgatgat 23640 aaatgcagaa attttttaaa tatgaacacg tagaaaagta aaaaaaatat catgtaaagg 23700 gtgagtacac taaattaagt gtaagaatgc aaaggaagca gcatcagaac tatatgaaat 23760 tgttaccata attttctaat tttaaaaaag cagaagcaaa ggacaagcta attctattca 23820 gtagcaaaac tggaaaatcc tctgaaacac tcttgttgtt gtcgtgtgag aacagtattg 23880 acaggtgtca aagttggaca tgcacctaat cgatcgttag taattaacca tattttaaca 23940 attgtcatac ttgtaaattc ttcatcaaaa ttattgaggt ctcggggatc gttgataagc 24000 ggtttatatg atggttcata aagtttgtta tacaagtcat cccagacaat actagcaaag 24060 aaaggatgag ccataacctc gtttgcgtct tttggtccac taccaagtcg ttgatttgga 24120 tctcttgtta aaagctattt tttgaattag ttaacatatt tagaaatttg catacccctc 24180 tcaataacga aaccgcatcc gctggcatat taatcggaaa caacggttca tcgcttaaaa 24240 tcgcatcgaa tatttcctct tcatcttcac ctttgaaagg ggattgaccc agtaacattt 24300 gatacatcaa aacgccaaaa gcccaccaat caacatcctt ggaatattgc tgttctaata 24360 aaatctattt tcgttagata aaataaacca aaacaagttc cgccttactt ctggagccat 24420 gaattcgggg gtaccacaaa aggtggaagt tgtattgcca agcaacatat tttctttgca 24480 gagtccataa tcagcaattc gtatatgacc atcaggacaa agtagaatat tatccaattt 24540 caaatcacgg taagcaattc cattctcatg aaaatacttc aatgctaaac aaacctcagc 24600 accataaaat ctatggggtt aataaaaaat aaaaataaaa ataaaaataa agattgaagt 24660 actaccttgc acgtttcacg ctaaactgtt gacgttgaat atgaaccata aggtcaccac 24720 caagaatata ttccataacg aagtaaaccc tggtactagt ttgaaagctt gcaaaaagat 24780 tcagcaagaa cggatgtttt tctttattcg cgacttcgaa aacatgcttt tcagttttta 24840 aactctctag ttcctcattc tttaaaatgg cttctttttt cagaactttg atggcataaa 24900 actttttatt cactttatat tcagccaaca taaccttgcc aaaattgcct ttccctaata 24960 cagccaaaaa tgtgaagtcg tcaagcgtaa cacgattctt tttctctctg cgtggacttt 25020 ctggaacact tctattagca tccttggaag acgataagct agcactggaa ggtggagcaa 25080 gaacagaagc tggagtagga gtagaagagg aaggagtaac atttaaagat cgatctttct 25140 caggggtttt tggaagtgga gacgtattaa gtacacttgt aactggctga gtagcagcaa 25200 gtaagccctg agatatcgtt ggtaatgtat caaaagtatt ttgactggat aacggctttc 25260 gataaacttt ttcattggtg gttttgtttt cctgattagg caattctggc ttctttggac 25320 gtttagagac ttcaagttca gttaagagtt gatgtttaag atcattagac atgccacaat 25380 agtcaggaat taggtgtgca cattgtccat ggcaagtaat accacattcc acacatttga 25440 aacagtcttt acgacgtaat ggcaaaaaga aaccacaatg ggcacaccat tgagctccta 25500 aagaattaaa aggttcaaaa cgatgaggga ttctgtatcg aagaccaccg aaatccgact 25560 tttcagaatt tgattgagca atgcagctag ccagtacttt ggtgacacat tttttatgac 25620 aaacaaaact gcagttttca cattgtaaac caggagaata cgaaaaaagt tctgcacata 25680 cagcacaccg cataatttgg taaaattggc gttgtacaaa ttgatgacca acttgagacg 25740 caacaacatc ttccttcttt tggcgaatgg ctccttgacg tcccaaacca gtttctggaa 25800 attgacgttt ggtggtacgc tttgaaaagg acaatgaaat gcatatctgc ccaaccggtt 25860 ccaatgaaag ccaagactta gataacagct tataataggc agtaggtgct aatggggaat 25920 tagtagaaat gctggaagag ctattagggg catttatagg atcagatttt gacccttttt 25980 catcggaacg tgaagccgac tcagctattg atggtttcca actagtttcc gacatttctt 26040 gaatgttcct ttttctacgc aattcctcag caatgatagt agttggaata agaataaggg 26100 caatgggaat atcaaagtct ttcttctttt cataaataat tatttgaaat tctttggcac 26160 gatgtacatc gaagataaac gtctcatccc atgtgtctgt ttgagaaatc cgagacttag 26220 caacttgtgc atcatcaacg taaagaacag catatgaagg cattgtaaat gaatgcgttt 26280 gaagaaatga tgtatgttca atatttctta gagaatgaat ggtaaccttg agggttccag 26340 atataggttt ggctagacct cgaaaattaa gaccactagc ctgttgcttt tcctcagaag 26400 aaggtgtaga aatatcaaag gggatatgta gttcattata ccgcttcaaa gagcgtttta 26460 atagattgac cttttgctta ccctctttca actttataat aacatcagtt ttatccttct 26520 gttctttaga gtaaagagac atgatttttt caatgcccga aacacattgc tgctctatcg 26580 acaatctcat ttgaagatgt tgtaacatag tcgagatttt ttcaggactt aatggcttct 26640 cggagttgaa aagatcaaaa gcgcttctgt tgtaacttaa aagatgatc 26689 //