ID SPAC1782 standard; DNA; FUN; 21352 BP. XX AC AL158056; XX SV AL158056.1 XX DT 02-MAR-2000 (Rel. 62, Created) DT 02-MAR-2000 (Rel. 62, Last updated, Version 1) XX DE S.pombe chromosome I cosmid c1782. XX KW adenylylsulfate kinase; bacterial-like hypothetical protein; CDC14 homolog; KW cell wall stucture/biosynthesis; coiled-coil; confirmed intron; KW exonuclease; human microfibrillar-associated protein 1; Nucleolar protein; KW phosphotyrosyl phosphatase activator; prohibitin; KW protein-tyrosine phosphatase; qcr8; rapamycin sensitivity; KW ribosomal RNA pseudouridinylation; KW ubiquinol-cytochrome c reductase complex ubiquinone-binding protein qp-c; KW yeast Ecm29. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-21352 RA Wood V., Rajandream M.A., Barrell B.G., Brown S., Harris D.; RT ; RL Submitted (29-FEB-2000) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; P50523; P50523. DR GOA; Q9P7G9; Q9P7G9. DR GOA; Q9P7H0; Q9P7H0. DR GOA; Q9P7H1; Q9P7H1. DR GOA; Q9P7H2; Q9P7H2. DR GOA; Q9P7H4; Q9P7H4. DR SPTREMBL; Q9P7G8; Q9P7G8. DR SPTREMBL; Q9P7G9; Q9P7G9. DR SPTREMBL; Q9P7H2; Q9P7H2. DR SPTREMBL; Q9P7H3; Q9P7H3. DR SPTREMBL; Q9P7H4; Q9P7H4. DR SPTREMBL; Q9P7H5; Q9P7H5. DR SPTREMBL; Q9P7H6; Q9P7H6. DR SPTREMBL; Q9P7H7; Q9P7H7. DR SPTREMBL; Q9P7H8; Q9P7H8. DR SWISS-PROT; P50523; UCRQ_SCHPO. DR SWISS-PROT; Q9P7H0; NHP2_SCHPO. DR SWISS-PROT; Q9P7H1; FLP1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1782 is overlapped at the 5' end by small insert clone CC pYUG7 EM:AL136521 and at its 3' end by cosmid c11H11, CC EMBL entry SPAC11H11, accession number AL132714. XX FH Key Location/Qualifiers FH FT source 1..21352 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1782" FT /map="IR" FT misc_feature 1..898 FT /note="nominal overlap with pYUG7 S. pombe chromosome 1" FT CDS 415..5454 FT /db_xref="SPTREMBL:Q9P7H8" FT /label=SPAC1782.01 FT /note="SPAC1782.01, len:1679, SIMILARITY:Homo sapiens, FT O15074, kiaa0368, (1441 aa), fasta scores: opt: 1047, FT E():0, (24.8% identity in 1407 aa)" FT /gene="SPAC1782.01" FT /product="similar to yeast Ecm29 cell wall FT stucture/biosynthesis protein" FT /protein_id="CAB76263.1" FT /translation="MAENELRLLNNAELKLALAESEDSFQSLVSVFLCPILLKLDSPHE FT SVRNKTISIANHIMTRLNNNAQAILPLEALVSQYVEANQPLRKRFLLAFISIGEKRIPC FT SENLALLQICLNHVNEYPLVLLTLTIRLLRFSKPTSAITCSNDVILSLSSFYLIQKDQR FT IFSDLQFSQKTVDYRLSLLRWIHLSSWPSNWKWLAYFFASADSHSEVARLADEFTRDSG FT LPDLENLSHVNVLLDIALDKFRIEALHANFSVSISLRNKAIQHLLKSKIAANTDKAINC FT IEFILEAPPSMQPRLIQFTRWVVDKADPNFLKPKAAMILEKILSILSSNIIQSDLLRGF FT LYTTIGLLTKVDNHLITNSLLTNLLTSLQSELPDVRVSIDEALSIIIPYYSNFRFSNEL FT LPVLEPFIFDSPESPAAYCALRFVLVAFPFDYLPARFICLKVQNPFVFHHSFIEEAKKG FT LNLSQWVQYNSVYSTNEAQEEDKVRAASYPSASEVISFILSDHDLKKFWESNAAEYCLA FT ILEFIERCIYYSADRSLELYDNDKLSSIDALLIQDSKLREMVSEKCISLSNFNVFLEYV FT FYGTLLMHFEPTYALSRLVSFAPPEVTFSLPELDFLTSVFNFPLALRNTATRILGIILS FT TKDSTRISEVLSSCFTIISTSNNKNDNFFKAETALLIIGYTISYLAAQTNSAAVDSFIL FT NSGSIKEFFSVLLEYLGSNVLHKKTTSLAIYKELFVYFTRDWITSYGVDFDEILNVLLR FT FLKEVEDTNVKVECLHVISRMSLSFSDDEMAEKILKAIYVTYHMDSPDILFASAEAMSI FT LAGGHRNVFVKSTCPIFFQKQLDNYKADHYCFTLDFILTDCVNSPKPLLRRASSLWLFY FT IVRYCEPQTYTMTRLNDIYHSFLSFLVTQDDFVQDTASRGLKAMYDVLEGDERKSFTDN FT LISTIAADRVDEKTKAPLDADTALFTTNKGTVATYKDICSLASESGNPDLIYSFLSIAG FT NSSLWQARKGLASGISYLGIPEDQKRKTFSFDTSKSSSLLKKLYRFKHDPNPDVAKTMG FT EIWDTLVPSDLNLASHRKYLVEDCLEFMGSRSWRDRESSVNTLVSLLSNVPVTEYLNQL FT EDIWNMSFRTLDDIKESVREASFPLCKLLARSVIQSLEKTSHNTSPSGICKGKRIVSVA FT LPFLLKHAYDQAKEVRSLTYSTITELVRTGNSTLTSFVPAIMQVMLEYLTEYESKAATF FT LDFHAKNYSIKQENIDNARTSAVQSSSMMDTLEKCIGLLDESSMQTLYPILNRMIAKPG FT GVPTKIGSAQVVMLLVIRRGPLVKQFASKLLQSLKSSCFDRNAAVSDAFASAIGYLLRV FT CPLEIASQTCQEIIDKFYDGNTNEQIISSKLTVYASRYAPDVFLNLGSLFFPFIFFGKH FT SSSISINGVLSKAWDELSSAGSSVNLYSEEIILLIQKNLIVTKWDVKRPAAAALLEFVN FT TSRLTYRQNDIYVLLNETMKDKSWPGKELLLEAYVKFLIKYPEFIKSQKMEEVHQVIVR FT EFKRRNIVYKSHAMESVGELLSDENYRELDLYELSLNECGTFLQKEWFDKDDELNLEEK FT IALQRNSVYAMFNSSRPGNKNCNEMLLTYLSNALDENYLHWNVKLAILKNAPHLKKIMS FT NEEFLLYKDILYRCYEDNPSPKAKDYAEVIFGENYLSVLRN" FT CDS join(complement(6160..6294),complement(5709..6059)) FT /db_xref="SPTREMBL:Q9P7H7" FT /label=SPAC1782.02c FT /note="SPAC1782.02c, len:161, ptredicted to contain FT coiled-coil region, SIMILARITY:Saccharomyces cerevisiae, FT YJ88_YEAST, hypothetical 23.6 kd protein in ste24-atp2 FT intergenic region., (203 aa), fasta scores: opt: 162, FT E():0.00018, (26.8% identity in 142 aa)" FT /gene="SPAC1782.02c" FT /product="hypothetical coiled-coil protein" FT /protein_id="CAB76264.1" FT /translation="MLFSFRAIVLFYCCMLTFAGIGFLWNPKFVVESGLVALIGASMEV FT KPLIVTQDNLSTLALSGLVFLILGMIYTISLLQSNFLFFSGITPIRAIFDFILTGFIYL FT KKEHIASNSLTFTFAFCDLMWQFWMFAAMSEERAKYLKNQKKAEELAARKAREVEES" FT misc_feature complement(6060..6077) FT /note="ctgaccattataatttag, splice branch and acceptor" FT misc_feature complement(6154..6159) FT /note="gtatgt, splice donor sequence" FT mRNA 6670..7138 FT /note="mRNA from AU009439 492 24" FT CDS 7215..8282 FT /db_xref="SPTREMBL:Q9P7H6" FT /label=SPAC1782.03 FT /note="SPAC1782.03, len:355, SIMILARITY:Homo sapiens, FT MFA1_HUMAN, microfibrillar-associated protein 1., (439 aa), FT fasta scores: opt: 473, E():1.9e-20, (32.9% identity in 347 FT aa)" FT /gene="SPAC1782.03" FT /product="similar to human microfibrillar-associated FT protein 1" FT /protein_id="CAB76265.1" FT /translation="MPIDTPLIPHKPISRYRSGRLEGLESESSSESDYEEVSDSHDQEN FT SISSSRHVITPVFEKEGISETKTSSNFQNINPVQTIDNSASEYETDASSAEGGSNSAAS FT SSEEEDSSDSEYEMELRRRTLLLPPKFTSKVIKNRAKANEEDTEVLKKVTSQKILEETI FT KRELLLKETKNNNELLNDIDDTDGIDPQSEYELWKLRHLLRKKRDKEKSLELEREKMAI FT EERRLMNSEEREAQDLKDAEASRRGKKKSSMQFLQKYYHKGAFYQNEDIVSKRDYSEAT FT EGEVLNKDLLPKPMQIRGDLFAKAGQTRWTHLANEDTTKEGSAWYDPKNPILQKNLHRL FT GGLHSDSPLSKRKRT" FT mRNA 8306..8712 FT /note="mRNA from AU013208 2 408" FT CDS join(8487..8643,8686..9056) FT /db_xref="SPTREMBL:Q9P7H5" FT /label=SPAC1782.04 FT /note="SPAC1782.04, len:175" FT /gene="SPAC1782.04" FT /product="hypothetical protein" FT /protein_id="CAB76266.1" FT /translation="MLRRGALSTILKGLNGLSLRSPIPIWHVSASPEVGSKYNLPTVPT FT TSHVSYRQIAKANFFAGYRPLSANQICVPKVESKTQVSQSQDEEDQPQEYVLSLEDGYL FT YAQSFSASGSVTQTQPARISTQVWEQICDKLISITPLDLTSVKRKRKLKMNKHKFKKRL FT RRQRALRKRLGK" FT misc_feature 8644..8649 FT /note="gtaagt, splice donor sequence" FT misc_feature 8669..8685 FT /note="ctaacttcattgcgtag, splice branch and acceptor" FT CDS 9857..10915 FT /db_xref="GOA:Q9P7H4" FT /db_xref="SPTREMBL:Q9P7H4" FT /label=SPAC1782.05 FT /note="SPAC1782.05, len:352, SIMILARITY:Saccharomyces FT cerevisiae, Q12461, orf ypl152w., (358 aa), fasta scores: FT opt: 951, E():0, (48.6% identity in 358 aa)" FT /gene="SPAC1782.05" FT /product="homolog of yeast protein involved in rapamycin FT sensitivity; similarity to phosphotyrosyl phosphatase FT activator" FT /protein_id="CAB76267.1" FT /translation="MLSREEQNRCFVPVRRILDNEDLKLFKEGDAYKLIDSFICDLDEA FT VKDKPISASIPQSSSIEHVLNILDRVGEIKQENPAIDNMGSRFGNPAFQSFYDQVYIET FT PKLHQVFGIEHNAAMEAGRYFYESFGNRKRIDYGSGHELYFMSWLLILKQLGIFTKNDY FT PALVVRVFVKYVELMRSLQIFYTLEPAGSHGVWGLDDFHFLPFLFGAAQLVNHKYLRPK FT HVRDPEILEMCRADYMYLGYVYFLNKLKPSVSLRFHSPMIDDISAVKTWSKVNEGMIKM FT YRAEVLGKLPIMQHYLFGHLIPASPGMSPAPQDGDDSEVTHVHSHYADCCGIKIPSAIS FT AAKNNGSRIPFD" FT CDS complement(11374..12222) FT /db_xref="SPTREMBL:Q9P7H3" FT /label=SPAC1782.06c FT /note="SPAC1782.06c, len:282, SIMILARITY:Saccharomyces FT cerevisiae, PHB_YEAST, prohibitin., (287 aa), fasta scores: FT opt: 1256, E():0, (69.1% identity in 282 aa)" FT /gene="SPAC1782.06c" FT /product="putative prohibitin" FT /protein_id="CAB76268.1" FT /translation="MAVVLERVARYAIPIGIGFTLLQSSIYDVPGGKRAVLFDRLSGVQ FT KQVVQEGTHFLIPWLQKAIVYDVRTRPRNIATTTGSKDLQMVSLTLRVLHRPEVGMLPQ FT IYQNLGLDYDERVLPSIGNEILKSVVAQFDAAELITQREVVSAKIRQELVQRATEFGIR FT LEDVSITHMTFGKEFTKAVERKQIAQQEAERARFLVEQSEQERQANVIRAEGEAEAADI FT VSKALDKAGGALIQIRRLETSKEVATALANKGAQVTYLPFGAGSNAQSSSGSGLLLNVN FT P" FT misc_feature complement(11605..12192) FT /note="Match to PF01145 Band_7, Band 7 family Score 272.78" FT CDS join(12518..12549,12739..12756,12802..13015,13119..13133) FT /db_xref="GOA:P50523" FT /db_xref="SWISS-PROT:P50523" FT /label=qcr8 FT /note="SPAC1782.07, len:92" FT /gene="qcr8" FT /gene="SPAC1782.07" FT /product="ubiquinol-cytochrome c reductase complex FT ubiquinone-binding protein qp-c" FT /protein_id="CAB76269.1" FT /translation="MGGAAGGKTYLGWWGHLGGPKQKGIITYSLSPFQQRPMAGFFKTS FT TQNMFRRVMTEGLYVAIPFGIAYYIYCWGKERNEFLNSKHGRHLVEE" FT misc_feature 12550..12555 FT /note="gtaagt, splice donor sequence" FT intron 12550..12738 FT /note="intron confirmed by EST" FT misc_feature 12724..12738 FT /note="ctaacacatgaatag, splice branch and acceptor" FT misc_feature 12757..12762 FT /note="gtaagt, splice donor sequence" FT intron 12757..12801 FT /note="intron confirmed by EST" FT misc_feature 12788..12801 FT /note="cttactttaataag, splice branch and acceptor" FT misc_feature 13016..13021 FT /note="gtaagt, splice donor sequence" FT misc_feature 13103..13118 FT /note="ctaatatgtggtttag, splice branch and acceptor" FT CDS complement(13315..14937) FT /db_xref="GOA:Q9P7H2" FT /db_xref="SPTREMBL:Q9P7H2" FT /label=SPAC1782.08c FT /note="SPAC1782.08c, len:540, SIMILARITY:Pan, Q28909, gor FT antigenic epitope., (427 aa), fasta scores: opt: 578, FT E():4.1e-30, (40.2% identity in 254 aa)" FT /gene="SPAC1782.08c" FT /product="putative exonuclease" FT /protein_id="CAB76270.1" FT /translation="MFSPLGQFKHIVCPFLRTGRKCQSRNCFFSHDFQNSTKISPPYSE FT NVEGYPKVKIEKSLPYKYDNCKLSICVPIVTTCIPYHSVENLNFNIRQNISTTLNLEKT FT NDSIKETKNENFRMDVLETYKCKQLNHQTTHLPTNTVLKKRSLFNDAISIVPNKKKQLV FT SAISTNSDSQGASSNIIPTPKYDSNSPAGHELRKRMTHLLYESYKDLGYSNAESSMLAL FT LDEKNICETANSKMIYSSSCKSKILSLKKAPKKNEIQGSTPDEKLESLVHSEEELILWG FT YNIGDVAPVNPPDELRECDRCGTRFADPRGPCTYHWGKLFREKQGGEKIRTYTCCGVKE FT GDSSGCIIEDNHVFKYRHLPYLASVHPFSYLPDSTNSKQLSHCALDCELCYTTNGMELA FT RLTVVAKESIIMDVFIKPKGKILSLNTRFSGIHDAKELESGITMDQMYIKIKELGMNKN FT TILIGHGLENDLNAMRLIHKRVIDTALLFTHARGPPFRYSLKYLTKKYLGTTIQTSTHD FT SEEDAVSALQLVFYKTKSNESQN" FT misc_feature complement(13321..13788) FT /note="Match to PF00929 Exonuclease, Exonuclease Score FT 38.81" FT CDS join(complement(17019..17067),complement(15399..16963)) FT /db_xref="GOA:Q9P7H1" FT /db_xref="SWISS-PROT:Q9P7H1" FT /label=SPAC1782.09c FT /note="SPAC1782.09c, len:537, SIMILARITY:Saccharomyces FT cerevisiae, CC14_YEAST, probable protein-tyrosine FT phosphatase cdc14, (551 aa), fasta scores: opt: 1300, FT E():0, (40.2% identity in 540 aa)" FT /gene="SPAC1782.09c" FT /product="probable protein-tyrosine phosphatase CDC14 FT homolog" FT /protein_id="CAB76271.1" FT /translation="MDYQDDGLGEMIEFLEDKLYYTSLSQPPKAELYPHMHFFTIDDEL FT IYNPFYHDFGPLNVSHLIRFAVIVHGIMGKHRQAKKSKAIVLYSSTDTRLRANAACLLA FT CYMVLVQNWPPHLALAPLAQAEPPFLGFRDAGYAVSDYYITIQDCVYGLWRARESSILN FT IRNIDVHDYETYERVENGDFNWISPKFIAFASPIQAGWNHASTRPKKLPQPFAIVLDYF FT VANKVKLIVRLNGPLYDKKTFENVGIRHKEMYFEDGTVPELSLVKEFIDLTEEVEEDGV FT IAVHCKAGLGRTGCLIGAYLIYKHCFTANEVIAYMRIMRPGMVVGPQQHWLHINQVHFR FT AYFYEKAMGRAIQQATAAEPLATPPRHPLNATNGTSQSNISTPLPEPTPGQPRKVSGHN FT PPSARRLPSASSVKFNEKLKNASKQSIQNENKASYSSYEDSEIQNDDETRTVGTPTETI FT SVVRLRRSSSQSNIEPNGVRSPTSSPTGSPIRRTSGNRWSSGSSHSKKSAQRSVSMSSL FT NNTSNGRVAKPKPSKSRLIS" FT misc_feature complement(16014..16424) FT /note="Match to PF00782 DSPc, Dual specificity phosphatase, FT catalytic domain Score 41.90" FT misc_feature complement(16964..16979) FT /note="ttaacatgttaaatag, splice branch and acceptor" FT misc_feature complement(17013..17018) FT /note="gtatgc, splice donor sequence" FT CDS complement(18090..18554) FT /db_xref="GOA:Q9P7H0" FT /db_xref="SWISS-PROT:Q9P7H0" FT /label=nhp2 FT /note="SPAC1782.10c, len:154" FT /gene="nhp2" FT /gene="SPAC1782.10c" FT /product="Nucleolar protein, possibly involved in ribosomal FT RNA pseudouridinylation, in association with snRNAs" FT /protein_id="CAB76272.1" FT /translation="MAKDKKDHKHSGSTEDEYDSYLPALMPIAKPLAPKKLNKKMMKTV FT KKASKQKHILRGVKEVVKAVRKGEKGLVILAGDISPMDVISHIPVLCEDNNVPYLYTVS FT KELLGEASNTKRPTSCVMIVPGGKKKDMSKVEEYKESYEEIIKEVPALEV" FT misc_feature complement(18165..18449) FT /note="Match to PF01248 Ribosomal_L7Ae, Ribosomal protein FT L7Ae Score 127.70" FT CDS join(19200..19668,19775..19914) FT /db_xref="GOA:Q9P7G9" FT /db_xref="SPTREMBL:Q9P7G9" FT /label=SPAC1782.11 FT /note="SPAC1782.11, len:202, SIMILARITY:Saccharomyces FT cerevisiae, KAPS_YEAST, adenylylsulfate kinase, (202 aa), FT fasta scores: opt: 894, E():0, (65.8% identity in 199 aa)" FT /gene="SPAC1782.11" FT /product="adenylylsulfate kinase" FT /protein_id="CAB76273.1" FT /translation="MATNITFHPGSVTKEERIKFVGHPGMTIWMTGLSASGKSTIACAL FT EQYLLQRGVTTYRLDGDNVRFGLNSDLGFSEQDRNENIRRIGHVAKLFADACVVAVTSF FT ISPYRKDRDQAREFHKKDGLPFIEVYVECPVEVAEQRDPKGLYKRARAGEIKEFTGISA FT PYEAPISPEIVVSSHTQSIEECVEKIVNYLLEKDLITLK" FT misc_feature join(19272..19668,19775..19851) FT /note="Match to PF01583 APS_kinase, Adenylylsulfate kinase FT Score 355.62" FT misc_feature 19669..19674 FT /note="gtaggt, splice donor sequence" FT intron 19669..19774 FT /note="confirmed intron" FT misc_feature 19761..19774 FT /note="ctaaccggttttag, splice branch and acceptor" FT CDS join(complement(20572..20602),complement(20399..20475), FT complement(20094..20342)) FT /db_xref="SPTREMBL:Q9P7G8" FT /label=SPAC1782.12c FT /note="SPAC1782.12c, len:118, SIMILARITY:Escherichia coli., FT Q46667, hypothetical 14.3 kd protein., (131 aa), fasta FT scores: opt: 214, E():1.6e-08, (37.1% identity in 116 aa)" FT /gene="SPAC1782.12c" FT /product="bacterial-like hypothetical protein" FT /protein_id="CAB76274.1" FT /translation="MTIWNVAALTGLLSVGLGAYGSHGLQKRVQDPHLLKSWSTACTYL FT MFHSLATMAVSLHPVYGKSRWTGPLLITGSCLFSGTIYGLCLLPKGHSLRRILGPLTPI FT GGLVMLTGWATMLV" FT misc_feature complement(20343..20359) FT /note="ttaacataaaattatag, splice branch and acceptor" FT misc_feature complement(20393..20398) FT /note="gtagga, splice donor sequence" FT misc_feature complement(20476..20490) FT /note="ctaacaataaaaaag, splice branch and acceptor" FT misc_feature complement(20566..20571) FT /note="gtaggt, splice donor sequence" FT misc_feature 21252..21352 FT /note="nominal overlap with SPAC11H11 S. pombe chromosome FT 1" XX SQ Sequence 21352 BP; 6855 A; 3834 C; 3738 G; 6925 T; 0 other; gatcacgaat gccttattac agcacggtca aaaaaataca tccgacgttg atgattcctc 60 ggattcttct tcagatgtag atgaagaaac tttaatcgta tcaaaaagta aaaaagctca 120 taaagatatt cctaaatttt ccgcacctcc tccttctgct gacctcaata acctcatcac 180 tgattcactt ccttaagtcg catgctgtta gtcagccttt taacctacga aatacaacac 240 acacatccaa aattgtagat tttatttatg ccttgttcta tcaattaagt gtaaagtcaa 300 tttgggactt ttttttaatt acttgctttc tgatatatat ctctttattc atctttgttt 360 ggtattttat tgtagagtgt ttttttatta gtgattataa ttaactctac aataatggct 420 gaaaatgaat tgagattatt aaacaatgca gagctgaagc tcgctctagc ggaaagcgag 480 gactcctttc aatcgcttgt gtcagttttt ttatgtccga ttttactaaa actcgattcg 540 cctcatgaaa gtgtgagaaa caaaacaatt tcaattgcaa accacattat gactaggctc 600 aacaataacg cgcaagccat actacctctt gaagccttag taagccagta cgttgaagca 660 aatcaacctt tgcgaaaaag atttctcctt gctttcatat ctataggcga aaaaaggata 720 ccttgttctg aaaatttggc ccttctccag atttgtctaa atcatgtcaa tgaataccca 780 ttagtattat tgacattgac aattcgttta cttcgttttt caaagccaac ttcggctatt 840 acatgctcta acgatgtcat tttatctctt tcttcattct atttgattca gaaagatcaa 900 aggattttta gtgacctgca attttcccaa aaaacagtag attaccgctt gagtctgctt 960 cggtggattc atttatctag ctggccatca aattggaagt ggttggctta cttttttgcc 1020 tctgctgatt ctcattctga agttgcccga ctggcagatg aatttacgcg tgatagtgga 1080 ttacctgatc tagagaattt gtcccacgtg aacgttctat tagacatagc gcttgataag 1140 tttcgaatcg aagctttgca cgcaaacttt tctgtttcca ttagcttaag gaacaaggca 1200 attcagcatt tacttaaaag taaaattgct gcgaatactg acaaagctat aaattgtatt 1260 gaattcattc ttgaagcacc tcctagtatg caaccccggt taatacagtt tactcgttgg 1320 gtagttgaca aagctgatcc aaattttctt aaacctaaag ctgcgatgat attggaaaaa 1380 attcttagca tcttatcgag taatataatt cagagtgatt tacttagagg atttttatat 1440 acaacgatag gtttactgac caaggttgat aatcatctga ttactaattc tttgctgaca 1500 aatttattga cctccttaca atctgaatta ccagacgtac gagtttcaat tgacgaagct 1560 ctttctatta ttattccgta ctatagtaat tttcgatttt ctaacgaatt gttgccagta 1620 ttagaaccct ttatttttga ttcacccgag tctcctgctg cgtattgcgc acttcgattt 1680 gtattggttg cttttccttt tgattatttg ccagctcgtt ttatttgtct aaaggtacaa 1740 aatcctttcg tatttcacca ctcttttatt gaagaagcta aaaaaggact aaacttatct 1800 caatgggttc agtataatag tgtgtattcc acgaatgaag ctcaagagga agataaagta 1860 cgtgccgcta gttatccttc tgcctctgaa gtaatctctt ttattttgtc ggaccatgat 1920 ttaaaaaaat tttgggaatc taatgctgca gagtattgtt tggccattct tgagtttatt 1980 gagagatgca tttattattc agcggataga agcttagagc tttacgacaa tgacaagcta 2040 tcttctatag acgctttact gattcaagat tccaagttaa gagaaatggt gtctgaaaag 2100 tgcatttctt tgtcaaattt taatgtattt ttagaatatg ttttttatgg tactctactc 2160 atgcactttg aacccactta cgccctcagc agattggtat cctttgcacc acctgaagtt 2220 acattttctt taccggagtt agattttcta acgtctgtat ttaactttcc acttgctttg 2280 cgtaatactg caacacgaat actgggaata atacttagta caaaagattc aactcgtata 2340 tcagaagtac tttcttcttg cttcactatt atctcaacgt ctaacaataa aaatgacaat 2400 tttttcaagg ctgagactgc tcttctaatc atcggctata ctatctcata cttggctgct 2460 caaactaatt cagcagccgt cgattctttc attctcaatt ctggcagtat aaaagaattt 2520 ttttctgttt tattggaata tcttggttcc aatgttttgc acaaaaagac cacttcactt 2580 gctatttata aagaattgtt tgtttatttt actagagact ggattacttc gtatggcgtt 2640 gactttgacg aaattttaaa tgttttgcta cgctttctaa aagaggttga agataccaac 2700 gtaaaggtcg aatgtttaca cgttatatca cgtatgtcgt tatcattttc agatgatgaa 2760 atggcagaaa agattcttaa agccatctat gttacatatc acatggactc tcctgatata 2820 ttgtttgcga gtgctgaagc catgtcgata cttgctggtg gacatagaaa cgttttcgtg 2880 aaatccacgt gccccatttt ttttcaaaaa caattggaca attataaagc agatcactat 2940 tgctttaccc ttgatttcat tttaactgat tgtgtcaatt ctccaaaacc cttacttcgt 3000 agggcctctt ctttatggct tttttacata gttcgctatt gcgaacctca aacttataca 3060 atgacgcggc ttaatgatat ttatcattca tttctctcat ttttggttac tcaagatgat 3120 tttgttcagg atactgcgtc aagaggcctc aaagctatgt atgatgtttt agaaggggac 3180 gaaagaaaat catttactga taatctgata agcacaattg ctgctgaccg cgttgatgaa 3240 aaaaccaaag ctcctttgga cgcagatact gcccttttca ctacaaataa aggtactgta 3300 gccacctata aggatatctg ttctttagca tccgagagtg gtaatcctga tttgatttat 3360 tcattcttga gcatagcagg taacagttct ctctggcaag cccgtaaggg attggcatct 3420 ggtataagtt atttaggtat tcccgaggat caaaaaagaa agacgttttc atttgatact 3480 tctaaaagct cttcattatt aaaaaagctt tatagattta aacatgaccc taatcctgat 3540 gttgccaaaa caatgggtga aatttgggac acattagtac cttcagatct caatttggca 3600 tctcatcgta aatacttagt ggaggattgc ctcgagttta tggggagcag atcttggaga 3660 gatagggaat ccagtgtaaa cactttggtt agtcttcttt ctaatgttcc tgtgaccgag 3720 tatctaaatc aattagagga tatatggaac atgtcttttc gaactcttga tgatattaaa 3780 gagagcgtta gggaagcgtc ctttccactt tgtaagcttt tagcaagatc agttattcaa 3840 tctttggaga agacttcaca caatactagc ccaagcggaa tttgcaaagg caaacggatt 3900 gtttcagtag ctttaccatt tctattaaaa cacgcttatg atcaggctaa agaagttcgt 3960 tcacttacat actctaccat cactgaactt gtgcgtactg gcaattctac tttgacttcg 4020 tttgtgccgg ccattatgca ggttatgctt gaatatttga cagagtatga atcaaaagct 4080 gctacctttt tggattttca cgccaaaaat tacagcatta aacaagaaaa tattgacaac 4140 gccagaacgt cagccgttca gagctcttca atgatggata cgctagagaa gtgtatcggc 4200 cttttggatg aaagctcaat gcaaacatta tatccaatat taaatagaat gattgctaaa 4260 cctgggggtg tacctaccaa aataggcagc gcccaagtgg tgatgctttt agtaattcgt 4320 cgtggaccac tcgtcaagca gtttgcttca aagctgcttc aatccttgaa atcttcttgc 4380 tttgatagaa atgctgcagt aagtgatgca tttgcatctg ctattggcta tttgttacga 4440 gtttgcccgt tggaaatagc ttcacaaact tgtcaagaaa tcatcgataa attctacgat 4500 ggaaatacca acgaacaaat aatcagttcc aaattgaccg tgtatgcgtc gagatacgca 4560 cccgacgtct tccttaatct tggttctctt ttttttcctt tcattttttt tgggaaacat 4620 tcttcttcca tttcgataaa tggggtttta agtaaagcat gggatgaact ttcatctgcc 4680 ggaagcagtg tgaacctgta ttcggaagaa attatccttc ttatccaaaa aaacttaatt 4740 gttacaaaat gggatgtcaa acgtcctgct gctgctgcat tattggaatt tgtcaatact 4800 tcgcgactca cttatcgaca aaatgatatc tacgtgcttt taaatgaaac aatgaaagat 4860 aaaagctggc ctgggaagga attactgctt gaggcttatg ttaaattttt aattaaatat 4920 cctgagttca ttaaatcgca aaaaatggaa gaagttcacc aagtgattgt tagagaattt 4980 aagagacgca atattgttta caaaagccat gcaatggaaa gtgttggtga actgttatct 5040 gatgaaaatt atagagagct tgatttgtat gaactatcat taaatgaatg tggtacattt 5100 ttgcagaagg aatggtttga taaagatgat gaattgaatc ttgaggaaaa aattgcgctt 5160 cagcgcaata gcgtctatgc catgtttaat tccagcagac ctggaaataa gaattgtaat 5220 gagatgttgc taacttactt gtcaaatgcc cttgatgaaa attatttaca ttggaatgtg 5280 aaattagcaa ttctgaaaaa tgctcctcac ttaaaaaaga taatgtctaa cgaggaattc 5340 ttactgtata aagatattct ttatcgttgt tacgaagaca atccgtcacc aaaagcaaaa 5400 gattatgctg aagtcatctt cggcgaaaat tatttaagtg ttttaagaaa ttagcttcat 5460 tatatttata gctagtgata aagctgatca gccatttgaa ctttctaaac actcatttct 5520 aatgctaaca ttgtaaagga ttaattaaag aatattttat acaaaccttt gactaatgta 5580 ttcatatttg attttaaacc tagaatgtaa gcgattgatg ttgaaaatcc aataacgata 5640 ataatagctt ttacaacaaa taaacaacaa gtgaagaata ctagatgcca gtcacttggt 5700 tttttttttt aagattcttc aacttcacgt gcttttctag cggctaattc ttcggccttt 5760 ttttggtttt tcaagtattt agccctctct tcgctcattg ctgcaaacat ccaaaactgc 5820 cacatcaaat cgcaaaatgc aaaagtaaaa gtaaggctgt tgctagcgat atgctctttt 5880 ttgaggtaaa taaagccggt aaggataaag tcaaatatag cacgaattgg agtaattcca 5940 ctgaagaaca ggaaattgct ttgtaacaat gagatagtat aaatcattcc aagaatcaaa 6000 aataccaagc cggacaatgc aagagtcgat aagttgtctt gtgttactat caatggtttc 6060 taaattataa tggtcagata tcacttcaaa cattaatcaa gaaattaaaa aaaaaaaaaa 6120 aatactatct actaaaacaa taaagttata atcacataca acttccatag aagcaccaat 6180 taacgcgacc agtccacttt ctactacaaa cttgggattc cataaaaatc caatgccagc 6240 aaatgttagc atacaacaat aaaaaagaac tatcgctcga aaagagaaca acatcgtgaa 6300 atcagaagac gacaaatgag caactattaa cttctagaga ctgtactccg tggtttagaa 6360 agagaatgta aaactaataa gtttttttcg gaaagaaaat gtagagagtt tcgatgaata 6420 tttcgttcgt acttttgttt tctcaacgtc gcaccaatta tatgcacctg atttttgcta 6480 ttttacggta gtatcaagct ctgggaagta tgtactctca attaatggtt atattacgat 6540 agttgaactt aacttcacta ttgttgctag ttgccagcgc tcgctatctg tatttagaat 6600 tagaaggtga attgaattga gaaatataat caatataaca aaattacaag tatacgtttg 6660 gttttatttc ttcaaagtta ttttggtatg aaaaagtgag atgctgacag atttcaagtc 6720 aagaactcta tattttttaa aaccacttca acgaatttta ggatcttgaa aagtacatca 6780 tttttactaa ttataggagg gtattttcaa aggatatatt gtatgtagca tctaaataat 6840 ttttatgaag gtctcaaagg gttgacaacg gttgtttttg gaaatacatt acattgacca 6900 taaactgaaa cgatgtattt tacaaaaggc aattcaattt tacaaacttt cagctaaata 6960 taaattatgc caggattctc gttcatttga ctagaatgtg tgcttgtgat atttgttctc 7020 gcattggtaa gtgccccgaa acctctttgt aagtggcacc gtaccacaaa ttgcatacat 7080 acaatctatt atatcagata tacagtttta tcttgggtgg tagataatag atatataatt 7140 tccaattcat atttatattg ttttaccggt tgattgaaat ttgccaacca atttaataaa 7200 aagcgtttgt caagatgcca atagatacac cgttgatacc ccataaacct atttcaagat 7260 atcgctctgg tagattggaa gggctggaaa gtgagtcttc ttctgaaagt gattatgaag 7320 aagtttccga ttcacatgat caagaaaact cgatttcttc atcaagacat gttattactc 7380 cagtattcga gaaagaagga atatctgaaa ccaaaacgtc ttctaatttc caaaacatta 7440 acccagtcca aacaattgat aactctgctt cagaatatga gactgacgca tcatcggcag 7500 aagggggatc taactctgca gcatctagtt ctgaagaaga agactcttct gattcggaat 7560 atgagatgga gctgagaagg cggacacttc ttcttccgcc aaaatttact agtaaagtca 7620 tcaaaaatcg ggcaaaagcc aatgaagaag atactgaggt gcttaaaaaa gtgacttcac 7680 aaaaaatatt agaagagact ataaaacggg aattactatt gaaagaaact aaaaacaata 7740 atgaattatt aaatgatatc gatgataccg atggaattga tccgcaaagt gaatatgaat 7800 tatggaaatt aaggcatttg cttaggaaaa agagagacaa ggaaaagtca ctggaattag 7860 aaagggaaaa gatggcaatt gaagaaagaa gattaatgaa ttctgaggaa cgcgaagccc 7920 aagatttgaa ggacgctgaa gcaagtcgga gaggaaagaa aaagtcatct atgcagttct 7980 tacaaaagta ctatcataag ggtgcattct atcaaaacga agatattgtg agtaaaagag 8040 attattcaga agccacagaa ggggaagttc ttaataaaga tttattaccc aaacctatgc 8100 aaattagggg agatcttttt gcgaaggcag gccaaacacg ctggacgcat ttggcaaatg 8160 aagatactac aaaagaagga tctgcttggt atgatcctaa aaacccaatc ttgcaaaaaa 8220 atttgcatcg tctcggtgga cttcattctg acagcccact ctcgaagcga aaacgtacct 8280 aacatctgta tatacataag gacaattttg tatttcattt agcattaatt ttatttaaca 8340 tcacatatat atttaaatac aacattcttc tgaattaata tcaaatgtgc accacccttc 8400 ctctttgtaa gtgtttagca taagcatacc aattcttacc ttcccgcagt gcaaagagta 8460 caacacattt ttcgccttgg tcacccatgt tacgaagagg tgcgctttcc acaatattaa 8520 aaggtttaaa cggcctttca ctgcgtagtc ccataccgat ttggcatgtt tcagcttctc 8580 ccgaagttgg gtcgaaatat aacctaccaa cggttcctac aacttcacac gtttcatatc 8640 gtcgtaagta aattaaatac ttctatttct aacttcattg cgtagaaatc gcaaaagcaa 8700 atttctttgc tggatatcga cctttgtcag ctaatcaaat atgtgtgcct aaagttgagt 8760 ccaaaacaca agtttcgcaa tcgcaggatg aggaagatca accccaggaa tatgtgttat 8820 ctttagagga tggctatttg tatgctcaat cattctctgc atctggatcc gtaactcaaa 8880 ctcaacccgc tcgtatatct actcaagtat gggaacaaat atgtgataag ctgatttcta 8940 ttacaccttt agatttgacc agtgtcaaac gaaaaagaaa attgaaaatg aataaacata 9000 agttcaaaaa gcgcttacgc cgacaacgag cacttaggaa acgtctagga aaatgagatt 9060 attagaactt atttttactc gggttatatt tttaggttgg ttggattgag agtttaagct 9120 gtaaacaagc attttcaaaa tggctgcaag catttatgag tctctatttt taacttggat 9180 atcagtacct ctcttttctt aagaaacgtt taatcattta atgtttactt caggcttttt 9240 taacaaggaa tacattttct ctcatgtata ttctatcctt taatgttccg gtatgagaca 9300 attaggtcgg tgcttttttc ttgcgataaa atcattaaac aatccgcgtt tatttaacta 9360 ttttcaaaaa gcggagcact tatttgttta tgccggctat ctccttcata tcaattagct 9420 tcccatgtct agtactatta caatacctcc atctttggcc cttccttttt atatttttaa 9480 atatttgtcg atggctagaa ttaatgacat gtacacttca tgtgaatcat aaatatgttg 9540 ttgtatatca agcaattaat aaacgcttat tacactgtat ctgtttacac atagaataaa 9600 agaacacatt ggtatgaaaa ataactttag tagtcgaaat tatttcctta aaacaatttt 9660 gaaaaaaaaa aaaaaaattt ctacatttct ttctttaaaa aatgttctca ctgattatag 9720 ctaattacaa taatgaaatg taacgtactg acgactgaca taacaaataa caacataagg 9780 aatattgaag agcgtccaac tgtataattt ttaaggcttt tgttaatctt gtcttaaccg 9840 atcaagttat gccaacatgc tttctagaga agagcaaaac cggtgtttcg ttcctgtccg 9900 acgaatttta gacaatgaag acttaaaatt atttaaagaa ggagatgctt ataagttaat 9960 tgattcgttt atttgtgatc ttgacgaagc tgtgaaagac aagcctattt cagcttcaat 10020 tccgcaaagc tcatcaatag agcatgtatt aaatatacta gatcgagttg gagaaattaa 10080 acaggaaaat cctgcaattg ataatatggg gtcgaggttt ggcaatcctg catttcaatc 10140 attttacgat caggtataca ttgaaacacc aaagttgcac caagtatttg gaattgagca 10200 taatgcggcg atggaggcag gtcgatattt ttatgaaagc tttggaaaca gaaagcgaat 10260 agattatgga agtggtcatg aactttactt tatgtcatgg ttactaattt taaagcaact 10320 aggcattttt actaaaaatg attatccagc attggtcgtt cgagtttttg ttaagtatgt 10380 tgaattgatg aggtctttgc aaatttttta tactctcgaa ccagcaggat ctcatggtgt 10440 atggggatta gatgattttc atttcctccc ttttttgttt ggtgcagctc agttggttaa 10500 tcataaatat ttgcgtccca aacatgttag agatccagaa attttggaga tgtgtcgcgc 10560 tgattatatg tacttaggtt atgtttactt tttaaataag ttgaagcctt ctgtttcact 10620 acgtttccat tctccaatga ttgacgatat ttctgccgta aagacttggt ctaaagtcaa 10680 cgaaggcatg ataaaaatgt atagagcaga agttttgggt aaacttccta taatgcagca 10740 ctatcttttt ggccatttaa tcccagcttc acctgggatg tctcctgctc cccaagacgg 10800 tgatgattct gaggtgacac atgttcattc tcattatgct gactgttgtg gcatcaagat 10860 accaagtgcg atctctgctg ccaaaaataa tggaagtagg attccgtttg attaaaaatt 10920 ctcgagggaa aaaaggcgtt tttaacgaat cttcacgaat ttatgcgata cccatatttg 10980 tctgtttact ttaaaagtaa tatctaaagt caataaaatt accaacagta cagcatattt 11040 gtttatttca ttatgctaaa aaaactctac ataaacaatc aaccctaatt ttagcagcat 11100 taatatagcc atttcatcag cacaaaaccc aaaataattg tcgttttaaa aataaggtga 11160 caaatcataa ttttgagttc tgaaataaaa aaatttggaa atatttattt tcgttaagaa 11220 cccaaatttg tcaaaatcat aatgcgtgga aaagtacaac ttttatataa catctcttta 11280 attttaaagg gataataaga taaagctgat atgtttaggg gagctcgaat aaaccttatg 11340 aatttgctgc tagaagcaga tacatggaat gaattaagga tttacattaa gaagcaaccc 11400 agaaccactg gaactttggg cattagaacc agctccaaag ggaagataag tgacctgtgc 11460 acctttatta gcaagtgcag tagccacctc tttacttgtc tcgagacgac gaatttggat 11520 taaagcgcca ccggctttat caagtgcttt ggaaacaata tcagccgctt ctgcttcacc 11580 ctcagcgcga ataacattag cttgtcgctc ttgttcggat tgttctacta aaaatctagc 11640 acgctcggct tcttgttgag caatttgttt tctctctacg gctttcgtaa attcttttcc 11700 aaaagtcata tgagtaatgg atacatcttc caaccgaatt ccaaattcgg tagctcgttg 11760 aactagttct tggcgaattt tggcagaaac tacttctctt tgagtaatga gctctgctgc 11820 atcaaactga gcaactacgg attttaaaat ttcgtttcca atagaaggta agacacgctc 11880 atcataatct aagcctaaat tttggtaaat ttgaggaagc attccaactt cgggacggtg 11940 taatacacgc aatgttaaag aaaccatctg taaatcttta ctacccgtag tagttgcgat 12000 atttcgtgga cgtgtgcgta catcataaac aattgccttt tgtaaccatg gaatcaaaaa 12060 gtgtgtgccc tcctgaacaa cctgtttctg cacacccgac agacggtcaa acaaaactgc 12120 tctttttccc cccggtacat cgtaaatcga agattgtaat agagtaaatc caatacctat 12180 tggtattgca taacgtgcaa ctctctccag tactacagcc atctctttaa tagtacgttg 12240 agcgctggac taaaagacca aactgaaagg gaagtccgtt tgagcaagac taagtatgac 12300 ttaactgcaa cctctaggaa aatctatatt catgattaat aaatacatga tcttattatt 12360 tagaatttta atagtaaaac taaataaaaa tcttgaataa aaaaccaaga atttgtaaac 12420 gtctgaatta ttattggtct agcagacccg cacacttacc cttaacaaac atctgacttt 12480 gtaacggcaa tcatcaatat attattgttt taacaaaatg ggtggtgctg ctggaggaaa 12540 aacttatttg taagtgcaac ttaaagcagt ttctgtttat aatgggttat atgacttttc 12600 tttgacgctt atagcgtgag acggtggaca caattggtgt ttatttcgta aagccatttt 12660 cgtcagcgaa gttatataca ttcaaatagc tgctgagaat atcattgaac gtttttattt 12720 atactaacac atgaatagag gatggtgggg ccatctgtaa gtgctataac aatttgatac 12780 atttttactt actttaataa gaggtggacc taaacaaaaa ggaatcataa catattccct 12840 ttccccattt caacagagac caatggccgg cttcttcaaa acttctacgc aaaatatgtt 12900 tcgtcgcgtc atgactgaag gtctatacgt agcaattccg tttggaatag cttactatat 12960 ttactgttgg gggaaggagc gtaatgaatt cctcaattcc aaacatggaa gacacgtaag 13020 ttaatgactg aagaatcgat aagcagctat ggtttgcagc atttttctat acttctaaat 13080 tgtgtcaata attgtcattt tactaatatg tggtttagtt ggtggaggaa taatgatgag 13140 aatgaagtat tcattttggt agaaggattt acaaaattct tccctaccct ttccttattg 13200 ggtttacaat tactatctct ctcctctcat tatgcttagt atcagaaatc tatatatcca 13260 acaaaattac tttgtgatat gatctatctc ttgaatttga aaacattatt actcttagtt 13320 ttgactttca tttgattttg tcttataaaa gacaagttgt aatgctgaaa cagcgtcttc 13380 ttcgctatcg tgtgtagaag tttgtattgt tgttcccaga tattttttag tcaaatattt 13440 taaggaatat ctaaacggcg ggcctctggc atgcgtaaat agaagagcag tatctatgac 13500 acgtttgtga ataagcctca tcgcattcaa atcgttttct aaaccatgtc ctattaaaat 13560 tgtattttta ttcatgccaa gttcctttat tttaatatac atttgatcca tggtaattcc 13620 tgattctaat tctttggcat catgtatccc gctaaatcga gtattgagac tcaaaatttt 13680 gcctttaggc tttataaaca catccataat aatgctttcc tttgctacca ccgtcaaacg 13740 agccaattcc atcccgttcg tagtgtagca tagttcacaa tctaacgcgc aatgacttaa 13800 ttgcttgcta tttgtactgt ctggtaagta ggaaaatgga tgaacgctag caagatacgg 13860 aagatgtcgg tatttgaaca catggttgtc ttctataata caaccagacg aatcgccctc 13920 ttttacacca cagcaagtgt atgtacgaat cttctccccc ccttgctttt cacgaaacag 13980 ttttccccaa tgatatgtac atggtcctcg aggatccgca aaccgtgtac cacatcgatc 14040 gcattcacga agttcatctg gcgggtttac tggtgcaacg tctccaatat tatatcccca 14100 tagaatcaat tcttcttccg aatgaacaag tgactcaagt ttctcatcag gagttgatcc 14160 ttgtatttca tttttcttcg gagctttctt aagagataaa attttagact tgcaggagga 14220 actgtatatc attttactgt ttgcagtttc acaaatattt ttttcatcga gaagagcaag 14280 catactactt tctgcattgg aatagcctaa atccttgtaa gactcatata acaaatgtgt 14340 cattcgtttt ctcagttcat gcccagctgg tgagttggag tcatatttag gagtaggaat 14400 gatattggaa gacgctcctt gagaatctga attagtacta atggctgata caagttgctt 14460 cttcttatta ggaacgatgg aaatggcatc attaaataaa gaacgctttt ttaatacagt 14520 atttgtaggt agatgcgtcg tttgatgatt caactgcttg catttgtaag tttctagtac 14580 gtccatacga aaattctcat tcttggtttc tttaatggaa tcatttgtct tctccaaatt 14640 taaagtggtg gatatatttt gcctaatgtt gaaattaaga ttttcaaccg aatgataagg 14700 gatacaggtc gtaactattg gaacacaaat agacagttta caattatcgt atttgtaagg 14760 aagtgatttt tcaattttaa cttttgggta cccttcaaca ttttcggaat aaggtggtga 14820 aatctttgtt gagttttgaa agtcatgact aaagaaacaa ttcctagact gacatttgcg 14880 tccagttcgt agaaatggac aaactatgtg cttaaactga cccaaaggtg aaaacattga 14940 agcaaattag gtacaacaag taggcagatt tccgttggga atttagataa aaattctcaa 15000 gcaaaatata ataaaatgta ccgctacgaa caaagatacc atgcacccgc gaaagaacct 15060 cttcagccaa aaatagaatg gcgaaatctt gaaattcgta ataaaaaaca aagacttttt 15120 atatcataac caaaacaatt tctcgattaa aatcattaac catggcttgc aaaaagccaa 15180 agttttttcc aaagaaatat gaatgttagt taacaaaaag gatagctaag acattaatgg 15240 tggtgatccc caccgcgcaa aggtgcgcta aatcagggaa tatttgtaaa gttaattaat 15300 gaaaaattat gcagggttga cacagtataa ttcaaagtta gtttatatga aaaaaaggaa 15360 tgtaaaaact gccatttaaa ccagtaatta caggtttatt aagaaattag ccggctttta 15420 gaaggcttag gtttagcaac acggccatta gaagtattgt taagtgatga catgctaaca 15480 cttcgctgag cacttttttt agaatgacta gacccactag accacctatt tccacttgta 15540 cgtcgaattg gactaccagt tggtgaggat gtcggagaac gaactccatt tggttcgata 15600 ttgctttgac ttgatgagcg acgcaagcga accactgaaa ttgtttcagt tggagttcca 15660 acagtccgtg tttcatcatc attttgtatt tctgaatctt cgtaactact gtatgacgct 15720 ttgttctcat tttggattga ttgcttggaa gcatttttaa gtttctcatt aaatttgaca 15780 gaggacgctg aagggagacg tctcgccgac ggtggattat gtccagaaac ttttctcggt 15840 tggccaggcg ttggttctgg aagaggagta ctgatattgc tttgagaggt accattcgta 15900 gcattcaatg gatggcgagg aggagtagct aagggttccg cagcggtggc ctgttggatt 15960 gctcttccca tcgccttttc gtaaaaatat gcacggaaat gaacttgatt aatatgtaac 16020 caatgctgtt gtggacctac aaccattcca ggacgcatta ttctcatgta agcaataact 16080 tcattagcag taaaacaatg tttgtatatt aaatatgcgc caattaagca tccagtacgt 16140 ccgagccctg ctttgcaatg aacagcaatc acaccgtctt cttctacttc ctcggtaagg 16200 tcaataaact ctttgacaag agaaagctct ggaactgtgc catcctcaaa atacatctct 16260 ttatgtcgaa ttccaacatt ttcaaaagtc tttttatcgt aaagaggtcc attaagccta 16320 actatcagtt tgaccttatt agcgacgaaa taatcgagaa ctatcgcaaa cggttgagga 16380 agtttctttg gacgtgtgct cgcatgattc caaccagcct gaataggact tgcaaatgct 16440 ataaacttag gagatatcca attaaaatct ccattctcca ctctttcata agtttcatag 16500 tcatgaacat cgatattacg tatatttagt atgctgctct ctcgtgctct ccacagtccg 16560 taaacacaat cttgaatcgt gatatagtaa tctgaaacag catatcccgc atctctaaac 16620 cccaaaaaag gaggttctgc ctgagctaaa ggggctaatg cgagatgtgg aggccagttt 16680 tgtactaaca ccatgtagca agctaacaaa caagcggcat ttgcacgcaa ccttgtatct 16740 gtagaagaat ataaaactat agccttgctt ttcttagctt gtctgtgttt tcccatgata 16800 ccatgaacta tcactgcaaa tctaataaga tgactcacgt tcagcggacc aaagtcatga 16860 taaaaagggt tgtagatcaa ttcatcatcg atagtaaaaa aatgcatatg aggatataac 16920 tcggctttag gtggttgcga caatgatgtg tagtataact tgtctattta acatgttaat 16980 caattttacg agatatttga gttaaacttc atgcataccc tccaaaaact caatcatttc 17040 accaagccca tcatcttggt aatccatcag acaagtaatt gcgaatctcg tctatattcg 17100 tcaaacccgt aatggttgag ttctaaattg tgtacctggg tgttggtggt ccttgtaaat 17160 agaagggatg ataatgcaca agaaaatatg tggggtgcga aacaaatgaa gacaaaagtg 17220 gattctaaac tatacacaac gttatgttga catttaatct tttctcttta ttaaaaaaaa 17280 aaagacatta acttttagca acactatagt aaataaacaa caataatcat tatcttacaa 17340 agtaagtaaa aatgcacatc aatttatgat aaacatacag aatacttttt gctcatacaa 17400 atacaaccca acttttttat ctgaaattcg atttgtttta gcaaatatat ttaaatccga 17460 taacaaaatc cggatagata accatataat tgccggacct ttaaagctac cctaatctat 17520 catttatgga tagcactgga aagcataata tttgtaaaca ttataatggt aagaacgacg 17580 ttgggtgaaa tttaagttag ttgtaaactg gttctaacac gccgcctctg aatactaaat 17640 agcaacctaa acgaataata aaactttttt gcgcaactag ttagaaataa acacaggcta 17700 aatccgtaat gaaacgatca gcgtaaacga aatttgagga aaaatcagtt gatatttcat 17760 cgctgttaca gcgatatacc attctcatat aagttggtaa atgatacgat attattgcta 17820 acaaagtttt ggaggtatag tgattagttt gctcgcaaac cagtctaaac ccataaaata 17880 ctagggcata agaaagaatg ataaaacact agattaaaaa ggaaattttt tgaaacctta 17940 aaaccgacca ttaagcaaaa cttcttttcg cttactatca agcaaacaga catgatatac 18000 caaaagttaa atcccaggat aaataccaaa ttttaatagt atataataat ctacattaaa 18060 tggctaagca tcttttagat attgaacaat taaacttcaa gagcaggtac ttcttttata 18120 atttcctcgt agctttcctt gtactcctca actttagaca tgtccttctt ttttccaccg 18180 ggaacaatca taacacagct agtaggtctc ttggtgtttg atgcttcacc aagcaactct 18240 ttggaaacag tatataagta agggacatta ttgtcttcac ataatactgg aatatgagat 18300 ataacatcca tgggagaaat atcaccagca agaattacaa gacccttctc tccttttcta 18360 acagccttta caacctcttt gaccccacga aggatgtgtt tctgcttcga agccttcttg 18420 acagtcttca tcattttttt gttcaatttt ttaggagcta aaggcttagc aattggcatt 18480 aaagcaggaa gatatgaatc atactcatct tcggtgcttc cactatgctt atggtctttt 18540 ttatcttttg ccatgataaa gaaatggaga aggataagtt tggaagccca aaagatgatc 18600 ccaataaaac ttttttcagt aacgctatgt agcggataat agtctgttaa gccatctgta 18660 taatacgtaa ttttaagata ccagctttgg taatattcct taaattgaca taatgcctac 18720 tattccacga acggagtatt ggaaaaattt actgtaaata gatgttgctg tcttccctac 18780 ttaaagatac tattttaaac tccctgacta gtcctaagat tatataatca tttgtattta 18840 tttagacaac cgaaacagca cttaaaaagg ccaaatcaac taaatgaact aagcgctcat 18900 ggtttaagct aaagggaaat tttcgttacg ttattcttaa ttcctaccga ggtgacttta 18960 cgactcctaa cgagacgcta acggataggc gtaattgcgc aattgctaaa aaataaaaga 19020 ttgtgactgt tccgaatgct ttcaaattgt gacctagtaa ttgtaactaa tagcgttaat 19080 catcaaattg aattcgttag attttgtgca gtaacagttg taaaatattt ttcaaattcg 19140 taccatttga tttttccaac aattaattag aagattggat tttcacattt ttgtttacga 19200 tggctactaa cattacattt caccctggtt ccgtcactaa agaagaacgt atcaaatttg 19260 tgggtcatcc tggtatgacc atttggatga ctggattatc tgcgtctgga aagtctacaa 19320 tcgcttgtgc tttggaacag tatttacttc agcgtggagt tacaacttac cgtttggatg 19380 gtgataatgt tcgtttcggc ttaaacagtg atcttggatt tagtgaacaa gatcgtaacg 19440 aaaacattcg tcgcataggt catgttgcca agcttttcgc agatgcctgt gtagttgcag 19500 taacttcctt catttctcct tatcgcaagg atcgtgatca agcacgcgaa tttcataaaa 19560 aagatggact tccttttatt gaggtttatg ttgaatgtcc agtggaagtt gccgagcagc 19620 gtgatccaaa gggtttgtac aagcgtgctc gtgctggtga gattaaaggt aggtaattgt 19680 tacacattaa agatactttt tcccctcagg aaattccatt ttctcaatgt ttttaaatag 19740 atgaccctat aaaattaagg ctaaccggtt ttagaattta caggaatttc tgctccctat 19800 gaggctccca tttctcctga aatcgtggtt tcttctcata ctcaatcgat tgaagagtgt 19860 gttgaaaaaa tcgtcaatta cttgttggaa aaggatttga ttactttgaa gtaaacacgt 19920 taactcatct taaatacttg tattcccctt atatcctttc tctctttttt gttcgcttac 19980 ttgggaccca ataaaatcat aacatattct ttatctgcta gtattttaga aacgacatca 20040 ttaatacttg cgtctgtact ggtaaaacaa aaagcatcta aattaaagct ctcttaaact 20100 agcattgtag cccaccctgt aagcatcact agtcctccaa ttggtgtcaa gggcccaaga 20160 attcgtcgca gactatgtcc tttaggcaat aaacaaagtc cataaattgt cccagaaaac 20220 aagcagcttc ctgtaatcag caggggtccc gtccaacgag atttcccgta aactggatgc 20280 aaagaaacgg ccatggttgc caatgaatgg aacatcaagt aagtacaagc agtggaccat 20340 gactataatt ttatgttaaa atagttacaa tcatgaaata aaaatgcata aatcctacct 20400 tcaataaatg tggatcctga acacgttttt gcaacccgtg agatccatat gcacctaaac 20460 ctacgctgag cagtcctttt ttattgttag ataacgtaaa ataggttgtt taacaaaaag 20520 taaatgtata taaaggttat ataccagtct attacttgtg ctagaaccta cctgtcaatg 20580 cagctacgtt ccaaattgtc attattgata aacaaatatc agataattct ttcaataaaa 20640 atgcaaactg ctcggtttat tgccgtaatt aacctttcaa tagtcttgca attgtagtat 20700 tgctggtgtt aaaagagaag tggaatacgt atgtgagaac aatgatcctc aattatagtt 20760 gctaccttag tttatattta tggatacgac acatttccaa aatattgaat aagaaatctg 20820 agcgtattgg tactttgtga atttttcata actgctccta tcagtctata aattcatatc 20880 ctaatattat atactatcag atcgtcaatt tcagaaattg agtatgtagc acttaaaata 20940 aacttggcgt taatgttaat atggcatcaa ttgaaaataa tcttgagtat cgttacctgt 21000 tttatcgctt gatataacga tatattgtaa tattatacag tttatttaaa aaagagatgc 21060 agcattgacg ttatttatta caacgataaa atgcgtaaag aaaacgacca tctgttcaaa 21120 atcaatttca caagtggtgc ttgcaattaa taggttttcg aaaaccagct aactttattt 21180 gatttcttta aatcctataa gatttaatca cgtgcttgca taagtgcgcc tcgtttcttt 21240 ttaccatgtc agatcatgca atcaatgaac acccttcacg aattttgaat acaattgaaa 21300 aggtaccgct tgttttttta ccaatttaac ctgaaaaata gattagattt tg 21352 //