ID SPAC13F5 standard; DNA; FUN; 15093 BP. XX AC Z99091; XX SV Z99091.2 XX DT 12-SEP-1997 (Rel. 52, Created) DT 16-FEB-2000 (Rel. 62, Last updated, Version 5) XX DE S.pombe chromosome I cosmid c13F5. XX KW disulphide isomerase; exocytosis; ferredoxin; gar2; glycerol dehydrogenase; KW mismatch repair; muts family; pre-ribosomal particle assembly; RNA-binding; KW succinate dehydrogenase; TBP-associated; TFIID; ubiquinone. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-15093 RA Brown D., Churcher C.M.; RT ; RL Unpublished. XX RN [2] RP 1-15093 RA Barrell B.G., Rajandream M.A., Wood V.; RT ; RL Submitted (07-SEP-1997) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA E-mail: RL barrell@sanger.ac.uk XX DR GOA; O13701; O13701. DR GOA; O13702; O13702. DR GOA; O13704; O13704. DR GOA; O13705; O13705. DR GOA; O13921; O13921. DR SPTREMBL; O13702; O13702. DR SPTREMBL; O13703; O13703. DR SPTREMBL; O13704; O13704. DR SPTREMBL; O13706; O13706. DR SWISS-PROT; O13701; T2D6_SCHPO. DR SWISS-PROT; O13705; SC10_SCHPO. DR SWISS-PROT; O13921; MSH1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c13F5 overlapped at the 5' end by cosmid c23C11. XX FH Key Location/Qualifiers FH FT source 1..15093 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c13F5" FT /map="Il" FT misc_feature 1..126 FT /note="nominal overlap with cosmid SPAC23C11, EM:Z98559 FT S.pombe chromosome 1" FT CDS complement(1..608) FT /db_xref="GOA:O13921" FT /db_xref="SWISS-PROT:O13921" FT /label=SPAC13F5.01c FT /note="SPAC13F5.01c, SIMILARITY:Saccharomyces cerevisiae, FT MSH1_YEAST, muts protein homolog 1., (959 aa), fasta FT scores: opt: 1246, E():0, (36.6% identity in 806 aa)" FT /partial FT /gene="SPAC13F5.01c" FT /gene="SPAC23C11.18c" FT /product="muts protein homolog; DNA mismatch repair FT protein" FT /protein_id="CAB11774.1" FT /translation="MPTWRYIFSLRSKSSFTKTWVPFTQIRNSSKSPKVGQKPILQGAL FT GPPLDFIRPKEKVTLPPLLKEVSFQQKKFADCVLLTKVGNFYEMYFEQAEKIGPLLNLR FT VSKKKTSKSDVSMAGFPFFKLDRYLKILVEDLKKCVALSEEVIRPVDDLSSKNMYIRSV FT TRVITPGTLIDENFMNPYESNYILTVVFDPNFFSSDISN" FT CDS join(complement(1938..2265),complement(1043..1896)) FT /db_xref="GOA:O13701" FT /db_xref="SWISS-PROT:O13701" FT /label=ptr6 FT /note="SPAC13F5.02c, len:393" FT /gene="SPAC13F5.02c" FT /gene="ptr6" FT /product="transcription initiation factor tfiid 55 kd FT subunit" FT /function="required for mRNA export" FT /protein_id="CAB11765.1" FT /translation="MVKLKIRAVQPPPNDSRSSTPATGPPPPIPKIKIKTREPKGPRLT FT KIRLKRVREPGLGYDSEASDREEDTYIEEQIILRLPPGEDCEYVRKAIENREVGRGADI FT WVKFKDQRRAVVHVNGHLYAAKLVDLPCIIESNKSFDKKVIFKAADICQMLIATERIEH FT ENSVLNTQLKQADYIYPHGLTTPMHWVRQKRFRKRVSNRTIEAVENEVDRLLAMDERAE FT STSNELIDQAQLARDSSIALSEDTSFDGMAGLRGTSIDRDDQSVQTDMFDGMDEDDLAG FT QIEQGMLELSQDTRESTAEPRAAGEESASEEEEEEEEEEEEENEADDETRENKRQNRLV FT REFISELESSIQKRRKDADEATNPILRNRFLADVNRMVTELELKRTQLVDNPE" FT misc_feature complement(1897..1909) FT /note="ttaacagagttag, splice branch and acceptor" FT misc_feature complement(1932..1937) FT /note="gtaatg, splice donor sequence" FT LTR complement(2412..2748) FT /note="Tf2 type ltr" FT CDS complement(3521..4873) FT /db_xref="GOA:O13702" FT /db_xref="SPTREMBL:O13702" FT /label=SPAC13F5.03c FT /note="SPAC13F5.03c, len:450, SIMILARITY:Bacillus FT stearothermophilus., GLDA_BACST, glycerol dehydrogenase, FT (370 aa), fasta scores: opt: 1052, E():0, (45.9% identity FT in 368 aa)" FT /gene="SPAC13F5.03c" FT /product="glycerol dehydrogenase" FT /protein_id="CAB11766.1" FT /translation="MIGPRLCAATPRFPLVSLAHRNSKVFALASSNAVAQRWGKRFYAP FT IETETPHKVGVEFEESKDRIFTSPQKYVQGRHAFTRSYMYVKKWATKSAVVLADQNVWN FT ICANKIVDSLSQNGMTVTKLVFGGEASLVELDKLRKQCPDDTQVIIGVGGGKTMDSAKY FT IAHSMNLPSIICPTTASSDAATSSLSVIYTPDGQFQKYSFYPLNPNLIFIDTDVIVRAP FT VRFLISGIGDALSTWVETESVIRSNSTSFAGGVASIAGRYIARACKDTLEKYALSAILS FT NTRGVCTEAFENVVEANTLMSGLGFENGGLAAAHAIHNGMTAIHGPVHRLMHGEKVAYG FT TLVQVVLEDWPLEDFNNLASFMAKCHLPITLEELGIPNVTDEELLMVGRATLRPDESIH FT NMSKKFNPSQIADAIKAVDSYSQKWQEQTGWTERFRLPPSRHSPHLTDIHP" FT misc_feature complement(3644..4669) FT /note="Match to PF00465 Fe-ADH, Iron-containing alcohol FT dehydrogenases Score 145.68" FT CDS join(complement(6959..7018),complement(6095..6868)) FT /db_xref="SPTREMBL:O13703" FT /label=SPAC13F5.04c FT /note="SPAC13F5.04c, len:277" FT /gene="SPAC13F5.04c" FT /product="hypothetical protein" FT /protein_id="CAB11767.1" FT /translation="MCFFFRLVSSFAILRISFLSITKSIKFCKLRALQVANPQRKAKTP FT SNHATEELQQSSTNSTTLPTQEAAVETNASASHETSFALPTTSPAASLSISPTKSAAVS FT SEPNVEADVKSLSSTPAAPQLNSPSHSYEPTTFPSTTSITENLPTIDPTRSTRSSSHIQ FT SLSPESKQTSDGHRPPSPTSITTTSTSIDPSVAFSSKSTLATTRTNAPLSRPSQPTKAS FT PLNKFSALEAIQSARSHARYAYSALDYEDTTTAIHHLKSALKLLEEEEQGNHTAD" FT misc_feature complement(6869..6889) FT /note="ctaacccctattgctacgtag, splice branch and acceptor" FT misc_feature complement(6953..6958) FT /note="gtattt, splice donor sequence" FT CDS 8585..9676 FT /db_xref="GOA:O13704" FT /db_xref="SPTREMBL:O13704" FT /label=SPAC13F5.05 FT /note="SPAC13F5.05, len:363, SIMILARITY:Aspergillus niger., FT AAC77456, pdi related protein a., (464 aa), fasta scores: FT opt: 425, E():1.6e-19, (33.3% identity in 225 aa)" FT /gene="SPAC13F5.05" FT /product="protein disulphide isomerase precursor" FT /protein_id="CAB11768.2" FT /translation="MLFRIPTLFTLFLACFSLVSGVFGYSPMFGSNTIELNSKNFRKFV FT KAKGPSLVVFYAPWCGYCKKLVPTYQKLASNLHSLLPVTAVDCDADQNRAVCSQYQVQG FT FPTIKLVYPSSKGSSLSSTDYNGDRSYKSLQKFVSDSIPSKVKILTSEAKTQKFIQDAQ FT NSSKVILISQKMKPTLLYKSLSNEFSSLPFSFMPAKANVNDLFNISAYVDTSDLPILFI FT KHPNNGTSFFSNSLNRDSIVEFLQSSIKDNNFSEYLATFCSKKSCIITIQDKDSDSGID FT ESIRKKYPKLHFVRLGRNTTVAERLEDTLDLGYSDTFLLSLKKSHYNAKPYGKPLRRWL FT EDIQVQQAGPSVSLPNDLLSKIK" FT misc_feature 8672..8998 FT /note="Match to PF00085 thiored, Thioredoxin Score 99.10" FT misc_feature 8738..8794 FT /note="PS00194 Thioredoxin family active site" FT CDS join(complement(12827..12889),complement(12702..12780), FT complement(10438..12472),complement(10280..10381), FT complement(10080..10236)) FT /db_xref="GOA:O13705" FT /db_xref="SWISS-PROT:O13705" FT /label=SPAC13F5.06c FT /note="SPAC13F5.06c, len:811, SIMILARITY:Saccharomyces FT cerevisiae, SC10_YEAST, exocyst complex component sec10., FT (871 aa), fasta scores: opt: 462, E():8.4e-22, (22.3% FT identity in 797 aa)" FT /gene="SPAC13F5.06c" FT /product="putative exocyst complex component" FT /protein_id="CAB11769.2" FT /translation="MSTKNALNDSQIKLLNSLNDNKGIPSTEFVEKFAESLYETQNDGS FT KKLSSIDGSIKSFAACLHELNRLKSRVGDRIRDYASASKQVQNEYHQKSNHLREKFAQV FT LELSRHLEDNVNDMRSGLVDAGQELERAENNRKRILSSAELLRYYLEFRSGKPQTLMDF FT FRTNNHDKMLLCAQRTRQLLALANEVDLPDSSETLARIEKFSEFLETNFLKFFNNEYRK FT PNWKGMASFGTILQEFNGGASVVREFVNQHEFFIAADKVQSRQGLEQDPIWLILPDPTQ FT KIPPLIQTLSSLFSELCSVIEGDCAVIKRVFPNPELVLQTFFQRIFGQSIQNRLEEVME FT IAKGKSNLAYLRTLQTVVSSLRKLVADLKTILENRGFSVSDNSPLSLALNQYMEDLLVP FT FIEVDDYLKREEHSLRSLFRLSLYKYTSYKIRLETPEPGLLRSLMTPLQGNMVAPTGVH FT SQFNTKTEGFLLRIADIQENLIQSGSFITEDYITIEKNHSHLNSEKVYSFIGWHAEALN FT RASILISSQDLSVVISSLVNLLDKLIREDYVFKELSSIQSYISSHDKSKNLDLHYLVDI FT RECKKIMGYFSAYLMSIVIPFTGVTASSRRETVNILSSSISVIECAVNDVFYATVHALG FT DHLEIILSPYRQISYAMTEEQIDSSTELRQSMTRNVQNYLDYIKNLYHRLGPYDPSLLA FT LKQKTATMLAAMLISFAFRSKVTAAGALLLQNDINFFHSTLTSWGIDTVDAKFKLILQL FT LSLLMVKIDVLPAVMQDKRKAGFSEMNIHEVLRLRFDLPENLKLQLNKEEALLPPKSS" FT misc_feature complement(10237..10247) FT /note="ttaacatttag, splice branch and acceptor" FT intron complement(10237..10279) FT /note="confirmed" FT misc_feature complement(10274..10279) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(10382..10395) FT /note="ctgactttatctag, splice branch and acceptor" FT intron complement(10382..10437) FT /note="confirmed" FT misc_feature complement(10432..10437) FT /note="gtacgc, splice donor sequence" FT misc_feature complement(12473..12489) FT /note="ctaacagaatgtttcag, splice branch and acceptor" FT misc_feature complement(12696..12701) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(12781..12794) FT /note="ctaacagattatag, splice branch and acceptor" FT misc_feature complement(12821..12826) FT /note="gtaacc, splice donor sequence" FT CDS complement(13378..13695) FT /db_xref="SPTREMBL:O13706" FT /label=SPAC13F5.07c FT /note="SPAC13F5.07c, len:105" FT /gene="SPAC13F5.07c" FT /product="hypothetical protein." FT /protein_id="CAB11770.1" FT /translation="MLKNIKNRLGEDDIVNSLDGITALSQEWIDKVVDAINEGHVSESD FT ERESRKLGEKMNVNSQKLKTSSPPKVVRKNKRHHTTVKSVLSDSDLDAEFTDGSEAYED FT D" FT misc_feature 13660..13800 FT /note="nominal overlap with SPBC2A9 S. pombe chromosome 2" FT misc_feature 14975..15093 FT /note="nominal overlap with SPAC1783 S. pombe chromosome 1" XX SQ Sequence 15093 BP; 4903 A; 2767 C; 2766 G; 4657 T; 0 other; tgattagaaa tatcggaact aaaaaaattg ggatcgaaga cgacagttag gatatagttg 60 ctttcataag gattcataaa attttcgtca attagagttc ctggagttat gactcgggtg 120 acagatctaa tatacatatt ctttgagctc aggtcatcaa ctggcctaat aacttcctca 180 ctcagagcaa cgcacttttt taaatcttcc accaatattt tgagataacg gtccagctta 240 aaaaaaggaa atcccgccat tgatacatca gatttagaag tctttttctt ggaaaccctt 300 aaattcagca atggacctat tttctcagct tgttcgaagt acatttcata gaaattacca 360 acctttgtaa gcaaaacaca gtcggcaaac tttttttgct gaaaactaac ttctttcaaa 420 agaggaggta gagttacttt ttccttcggt ctaataaaat ctaacggagg tcctaacgcg 480 ccttgtaaaa ttggcttttg gccgactttg ggggatttac tagaatttcg aatttgagta 540 aacggtaccc aggttttagt gaaagaagat ttacttctta atgaaaaaat atacctccat 600 gtcggcataa ttttcaggtt accgaatgga agggtttttt tgtagagtta gcaaaagttt 660 atgttactat aagcgacaat gaatgcatca ttgtcaagtt gaagaaatag taatcttcaa 720 gtatataaat ttatttatga gcatataaat gtatattaat aaatatatgt atacgtttaa 780 atagaattgc ttatgcagaa aaatgattgt tgtaataaag ttcggtacac ttcattaaca 840 aaactaattc tggctatcag tgtctaaaat acttaatatg caatttacaa tctactatat 900 aaaatataaa tatatgtata tatatccaaa ccataaccga tgttcattat tattgtagct 960 gatatgcaaa aggtaaaacg tatagaaata aatgcttttt tctttaaaaa aaaatgtaaa 1020 aagatgtaac tacgcaacac atttattcag ggttatcgac aagttgagta cgttttaact 1080 ctaactcggt caccatacga ttaacgtctg caaggaaacg atttcgtaga atgggattag 1140 ttgcttcatc ggcatccttt ctacgttttt gaatagaaga ctccaactct gaaataaact 1200 cacgaacaag tctattttgt cgtttatttt cgcgagtctc atcgtcagct tcattttcct 1260 cttcttcttc ttcttcctcc tcttcttctt cttcactagc agattcttca cctgcggcac 1320 gaggttctgc tgttgactcc cgagtatctt gactaagctc aagcataccc tgttcaatct 1380 gtccagccaa atcgtcctca tccataccat caaacatatc agtttgcacg ctttggtcgt 1440 cccgatcgat gctggtacca cgaagtcctg ccattccatc aaacgatgta tcctctgaaa 1500 gagcgatgct tgagtcacga gccaattgtg cttgatcaat caactcattc gatgtacttt 1560 cagcgcgttc atccattgca agcaatcggt caacctcatt ttcaactgct tcgattgttc 1620 tgttcgaaac acgttttcga aatcgcttct gccgcaccca atgcattggc gtcgtcaatc 1680 catgtggata aatgtaatca gcttgcttta actgagtatt gagaacagaa ttttcgtgct 1740 cgattctttc tgtagctatc aacatttgac agatgtcagc agccttgaag ataacttttt 1800 tgtcgaatga tttattagat tctatgatgc atggcaaatc aactaacttc gcagcgtaca 1860 aatgaccatt aacatgaaca accgctcttc tttgatctaa ctctgttaat aataatatag 1920 tgtaaccaag tcattacctt tgaacttcac ccatatgtct gcacctcgtc ccacttccct 1980 attttcaatt gcttttcgaa catactcaca atcttcacca ggaggaagac gtaatataat 2040 ttgttcttca atataagtgt cttcttctct gtcagaagct tctgaatcat atcctaagcc 2100 aggttcgcga actcttttta accgaatttt tgtcaatcga gggcctttag gttcacgtgt 2160 cttgatctta attttaggaa ttgggggagg aggaccagtg gctggagtgc tagatcgtga 2220 atcatttgga ggaggctgaa cagcacgaat ttttagctta accattttcg aaaaccgcct 2280 tttgagtaat tgtcgttggc aaacgctcga ttagcaagtc gctaaacctt caagtgagtc 2340 tcgttatcta ctactaacga gccatagtga tttacaacat ttttttaata caatcgttat 2400 ctgcaaacac ctgtcagcta cgcagtttgg tatctattta acgattcata gaactgcggt 2460 gagtttctct tgcgacctac agtatagcgg tatgtggtat gtttaactaa caatgtatat 2520 ttgttactat aagaagtcca ttagtatcga tcaccgacat agctaaacta ctgaactgag 2580 gaacaaggtt cggcagtagc cctatttata gtattcagat aataaaaata ttaatagatt 2640 attattaagg tcaatctcaa tactgtttca tacaacgatg aatgattagg acatgtgtca 2700 tatagtgata ctcaacgtag tgtatccttg agtaatgtat tgttgacaac actacttatt 2760 tatcccacag taaacaatgt aaataaagcg cgaaattgtt gatcgatgca aaggttaagg 2820 taaaaagggt tttcaatgta gctaggaatc cgggatttac tcacttatta taccatttgt 2880 agcatactaa tcatattgag ttagcatata atataataac aacgaatgtt tgacaaggcc 2940 actagcgaca attgtataat acgtgaaaac aaatcacttt agttatttaa agttttctaa 3000 cataggaaca ttattaattg taattacatt taaaactttt gaaatctatc acaataaaaa 3060 gcgattgcaa aaaaaaaaaa aaaaaaagga agcaacacag atgatgtgca ttgtaacaaa 3120 tagatcaatt acggtgaaca actttaatac aatacaacta acaacgataa aacattcatt 3180 tgaaaagggg aacaattttt ttcattcgta acaaaaataa agcaaattat tcatgaagtt 3240 ataaggggcg taaaaaactt tggagtaggc cgaaaaggtt gatcattaaa tcactagatt 3300 aacgggaaaa gcttacaact tttttaaaaa aataaaaaaa aggaagaaag aaaaaaggta 3360 aaaaaagttc caagaggaaa ggaagcacac gaaataaaag actactatag aaaaaaaaac 3420 actcaggaca ttaatgatca atgaagaaaa cccgcttaaa aatttctttt cttcttttgg 3480 atttactagg gaaaattgaa gctggggata aaaataatgc ctatggatga atgtcggtca 3540 agtgaggact atgacgagaa gggggtaatc taaaacgctc ggtccatcca gtttgttctt 3600 gccatttttg tgaataggag tcaacggctt taatagcgtc agcaatttga gatggattga 3660 acttctttga catgttgtga atactctcat caggtcgcaa agtagctcta cctaccatca 3720 ataactcttc atcggttacg ttgggaatac caagttcctc aagggtaatg ggaagatgac 3780 attttgccat aaaagaagca agattattga agtcttccaa cggccaatcc tccaaaacaa 3840 cttgaactaa ggtaccgtaa gcaacctttt caccatgcat taaacgatga acgggaccgt 3900 ggatggcggt cataccgtta tggatggcat gagcagcagc aagaccaccg ttttcaaagc 3960 ctagaccaga catcaatgtg ttggcctcga ccacgttctc aaatgcctcg gtacaaacac 4020 cgcgagtgtt ggaaagaata gcgctcaggg catacttttc aagagtgtct ttgcaagcac 4080 gggcaatgta acggccagca atggaggcca cacctccggc aaaggaagtg gaatttgagc 4140 gaataacgga ttcagtttcc acccaggtgg acaaagcatc accaatgcca ctaataagga 4200 agcggacggg agcgcgaaca atcacatcgg tatcgatgaa aatgaggttg ggattaaggg 4260 ggtaaaagct gtatttttgg aattgaccgt caggagtgta aatgacggaa agagaggaag 4320 tagcggcatc agaggaggca gtagtaggac aaatgatgga tggaagattc atggaatgag 4380 caatatactt tgcggaatcc atggttttac caccaccaac tccaatgatg acttgagtat 4440 catcagggca ctgtttgcga agtttatcca gttccaccaa gcttgcctcg ccgccaaaga 4500 ccagtttggt gacagtcatt ccgttttgag aaagagaatc gacaatttta ttggcacaaa 4560 tgttccatac gttctggtcg gcaagcacga cagctgattt agtggcccat tttttgacat 4620 acatatagga tctagtgaag gcatgacgac cctgaacata cttttgagga gaggtgaaaa 4680 tgcgatcttt ggattcttca aactctacac caactttgtg aggcgtctcc gtttcaatag 4740 gagcataaaa gcgtttgccc caacgttgtg caacggcatt ggaagaggcg agcgcaaata 4800 ctttagagtt cctgtgggcg agggaaacga gagggaagcg aggggttgca gcgcaaagac 4860 gaggaccaat cattatgaag gaagttcaaa gactagctaa gcgttacgaa tagaaatcga 4920 atcaaatcga agaaaagaga aatacaagaa taggcgtgtg gaacggttct tacctttctt 4980 gaaatttatt tcgatacaga agaatcctta tttaaaaaga aaaaggaaat aggtaaagaa 5040 gcacaagtaa ctaagaagga gagaaacgca atggaacaga ggtccaaaaa gaaaaaacaa 5100 ctatatgtgt atatatatac ttgtttgcgg aatcaataga cagtcgaaag atcacgaaag 5160 ttccaagaat gaacgggata tatgatctcg gctggccaaa aaaaaaggga tcgacgtagt 5220 caatggtgat tgtcaaaact agaatcagcc gatcgacggt aaacgggaag agtaggaaga 5280 atgaaaagag aaaaaatatt taaaaattaa agcaacgaaa gttgattaaa aaaataatta 5340 aagaaaagaa aaaaaaaccc aagtggtagt gaaaacttgc tatggtttta ttttacaatg 5400 gaaaaagcaa ttctgttaaa aaaagaagag aagagaagag gtggatggat ggatggatgg 5460 atgggggaaa tatggaaaac tgcgaaagca ataaccaaga gcaaagaatt cagcgctgcc 5520 cctctacata taaacttgat gagagggcga tgacaccaca catatccacc gcaattgcca 5580 gttccccact gcggaagcca aacccaagca gacaggaaaa taacgtaaca aaagatgagg 5640 caggataaac ccatgactcg ttggtctcat aactgcgtca taggggcaag aaagacaacg 5700 tggtatgcag tacaagacaa aagcttactt gctgaaaatc tggggaaata tatacaacag 5760 cagtcattcg ccagttcctt aataaacgct cgctaaaatg acgcgacaaa aaatgaggag 5820 acagggatga gcagtgccac tcaacggcga gggaaaatgg gaagagtgga gagaaaggcg 5880 gggtcctgct acaattagaa agcatttgaa gaaaaaaaag tggataaaaa aaaaacaaac 5940 aaataaacaa acattaagag agacgaatag tggggagagt ggtacaatta gattgtttct 6000 ccccaagatg gatagataat tttactggta tctgccccac cttttcccat tgtctcattg 6060 agatcccctc cattccagcc ccagcattct tcctctagtc tgcagtatga tttccctgct 6120 cctcttcctc caaaagtttt agtgccgact ttagatgatg aatggctgtc gttgtgtctt 6180 cgtagtctaa tgcactgtat gcatagcgtg catgacttcg agcagattgg atagcctcca 6240 aggcggaaaa cttgttcaag ggggaggctt tagtcggttg agatggcctt gatagagggg 6300 catttgttct tgttgtggct aaagttgact tgctggaaaa tgctactgac ggatcgatgg 6360 aggtggaggt ggtggtgatt gacgtagggg agggaggccg atgcccatct gatgtttgct 6420 ttgactcagg agataaactt tggatatgcg aggaagagcg agtggaacga gtaggatcta 6480 ttgttggcaa attttcggtt attgatgtag ttgaggggaa cgtggtaggc tcatatgaat 6540 gggaaggtga atttagttgt ggagcagccg gtgttgaaga caacgatttt acgtctgctt 6600 ctacattagg ctcggaagat acggctgcag actttgtagg agagatggag agcgatgctg 6660 ctggagatgt agtggggaga gcaaaagatg tttcatgaga agcagaggca ttcgtttcaa 6720 cggcggcttc ttgcgtaggt agggttgtgg aatttgtgga agattgctgt aactcctcgg 6780 tcgcgtggtt tgagggtgtt ttggcctttc gttggggatt tgcgacttgg agcgcacgta 6840 acttgcaaaa tttgattgac ttggtaatct acgtagcaat aggggttagt agggaacaaa 6900 aaatcgttat aagcatcata aagcatcgtt gtataataca aacgagagag aaaaataccg 6960 ataggaagga aatcctcaga atggcaaaag aagaaacgag tcgaaaaaaa aaacacatgg 7020 taatgtgaat tggaaaagac gattttgttt ttgacaaaac aaaaataaaa aataaaaaaa 7080 tttccaaaga accttcattt tttcattttt gttgatcgtg gttttctttt ttttttctcc 7140 taagttctgc tcgttactct ttttcattcc gtctcacttg ctctcgctgt ttttgactca 7200 cgtacctgtt ccgtaggtgg tccccagatt ctcgacaact ctagaaaatc tcgggctgcc 7260 aaatacgctt gcacatctgg tttcccgttt ttgctatttc tttcggcctg gacaagaact 7320 tctagggaaa acgattcaac atacgccttt gcactagtct cgtcactcac attctcattc 7380 tcgcccaaat ttttacgtaa ctacacacgc catagagcgg ttagtaccac agaaacattt 7440 acatagttgg tctcgtaatc caaaaaaaaa aaaaaagaga aaaaaccctc gccaacattt 7500 aaaaaaagga aaaggatgtt ttctaaactt acatcttcta aatgctcaat gagtgacagc 7560 aggaaatcct tgcattcgtt ggaaacaccg tgtgagctgg aaagcgccat ttgagctgcc 7620 cagtatagac ctagtaatag tacaagttag tgaatcaagc aaatgaatat ctcgaatgat 7680 gaaacaaatt cctttgtgct tataataggg tgtattatgg aaagtagtat tccctctagc 7740 gaaatgtaga ctatgaaaac ttcatcaacg taaacaagag agaaaaaagg tttaagttat 7800 ttttttatta ttttatattt ttctttctcc aatttttttt ttcatacacc cttccatatt 7860 acaaattcat cacttagcta ctaaacactt actccaataa gctatgacag gattgtgtgc 7920 ctcaagttca ttgaatcgtc tcacaaacgg ttgaatggat tgtaattcct tcggtatagt 7980 atctatttgt atcatatttt gtcaaatatc tctcctttca agtttctgta cttttggttt 8040 gacagttggt ggattacaga taccagctac atgatataaa aaggtagatg aaggttaggt 8100 ctactcaagt attaaaacca tcaagtcaat tattcaaaaa actctagtac taatagtttt 8160 gacgtacaaa cactttcttt tcatttgagg ggaatcaagt cgcatcgttt tcatcgtgca 8220 ttttttgtgc cccgctattc agatttttct agtgtcttga catactctac ctattctata 8280 tcaaaatgat gatttcaata agccttataa ctcattgatt gactaaaacc tattatttct 8340 tctaaatttt ctcgtgacat atgctcactc aaacctcaca ctaaagtggt tgtcgccgta 8400 aacctctcga tttttccatt caccaactac ttcccattgc atcgatcatt tgtagctagg 8460 acgtatttct tatttcattt tcgccaaacg gtttctattt ttttttattt cttcgatttt 8520 cattttcctt tctttcattc accttactac ccttaaaaat acgctggaca aactacacat 8580 cattatgctc ttccgtattc caactttatt tacgctcttt ttggcttgct tcagccttgt 8640 atccggcgtc tttggctact caccaatgtt tggatccaac acgattgagt taaattccaa 8700 aaattttcgt aaatttgtaa aagcaaaggg cccatcttta gttgtctttt atgctccgtg 8760 gtgtggttat tgcaaaaagc ttgtacctac ttaccaaaaa ttagccagca atctacattc 8820 actcttgccg gttactgctg tcgattgtga tgctgatcag aatagggccg tttgctctca 8880 ataccaggta cagggctttc ccactataaa gttggtttat ccatcttcca aaggatcttc 8940 tctttcctct actgattaca acggtgatcg aagttacaag tctctccaaa aattcgtctc 9000 tgattctatt cccagtaaag tcaaaatttt gacttctgag gcaaaaactc aaaaattcat 9060 ccaagatgct caaaactcct ctaaggtaat tctcatttct caaaaaatga agccgacttt 9120 gctgtacaaa tctctttcaa atgagttctc gagcttacct ttttcattta tgcctgcaaa 9180 agctaatgtg aatgatcttt tcaatatttc tgcgtatgtt gacacctccg atttacccat 9240 attattcata aaacacccca acaatggaac atcttttttt tcaaattcct taaatcggga 9300 ttctattgtt gaatttttac aatcttcaat taaagataat aatttttcag aatacttagc 9360 aactttttgc tcaaaaaaat cctgcattat tacaattcag gataaggact cggattctgg 9420 aatagacgaa tctattagga aaaagtaccc aaaacttcac tttgtacgtc ttggtcgaaa 9480 tacaacagta gccgaaagac ttgaagatac attggacctt ggttatagtg acacttttct 9540 tctcagtctt aagaaatctc attataatgc taagccctat ggaaaacctt tacgccgttg 9600 gttggaagat atccaagtac aacaagcagg accttcagtg tctttgccaa atgacctctt 9660 atcaaagatt aaataaacac acttattgta atgtaatttt gcactttgca gtacaatatg 9720 ttactctctt tctactcact cgttctcgtc attgcatttt atattttgtg tgaagctttc 9780 ctttacatga agcttaagca cttttaaaag ctatttttta tttaatttaa aataaagatg 9840 ttatacattc gtataattcc tttttgtctc cttcctttaa tgaattatta tgctcgtctt 9900 gctaatttta tatttcaaat acagattcac taaatgaaac ttaaataaag cgtttataaa 9960 aagtttgaga acgattttct ttacagaaaa aattatttat ataatacact ataaaagata 10020 ttatgtttat ctatagacaa attacttcat aattaagaca ttaacaaaaa tgagcgattt 10080 caactgctct ttgggggcaa taaagcttct tctttgttca gttgcaactt caagttttca 10140 ggcaaatcaa aacgtagacg gagaacttca tgaatgttca tttcactaaa acctgcttta 10200 cgcttgtctt gcatgactgc tggaagaacg tcaattctaa atgttaacaa actttctctc 10260 ctaaaagata ttcacttact tgaccataag taaacttaat aattgaagta tcaacttaaa 10320 tttcgcatca acggtatcaa ttccccaact agtcaaagta gaatggaaaa aattaatatc 10380 actagataaa gtcagtaaat taatcacttt cgataaaaaa caaaaaattg tgcgtacttt 10440 tgcaacaaca aagcgccagc cgctgtgact ttggaacgaa aagcaaaact tataagcatt 10500 gcagcaagca ttgttgccgt cttttgtttt aaggccaata acgagggatc ataaggtcct 10560 aatctatgat ataggttttt tatataatct aaataatttt gaacattcct agtcattgat 10620 tgacgaagct cggtagaaga atcaatttgt tcttctgtca tagcataaga aatttgccta 10680 tacggactta aaataatttc caaatggtct cctagtgcat gcacggtcgc gtaaaataca 10740 tcattaacgg cacattcaat aacggagatt gaggaactta gaatgttaac cgtttctctt 10800 cgagatgacg cggtcactcc agtaaacgga atcactattg acattaaata tgcagaaaaa 10860 tatcccataa ttttcttaca ttccctaatg tccactaggt aatgaagatc caagtttttc 10920 gacttatcat gtgaagagat gtatgattgt atagatgaaa gctccttgaa tacataatct 10980 tcgcgtatca gtttatccaa aaggttcaca agcgaagata ttacaactga caaatcttgg 11040 cttgaaatta agatagacgc cctatttaaa gcctctgcat gccagccaat aaatgaatat 11100 actttttccg aattaagatg gctatggttt ttttcaatgg taatgtagtc ttcagtaatg 11160 aatgaaccac tttgtattag attttcctga atgtcagcaa tcctcaaaag gaatccttca 11220 gtttttgtat taaattggga atggactccg gtaggcgcaa ccatattgcc ttgtagagga 11280 gtcatcagtg atcttaacag accgggctct ggagtttcta agcgaatttt gtagcttgta 11340 tatttgtata aacttagtcg aaataaagac cgtaaggaat gttcctcacg cttaagataa 11400 tcatcaactt caataaacgg aaccagtaaa tcttccatat attgatttaa agcaagagag 11460 aggggggaat tatcggatac cgaaaaccct cgattttcta aaatcgtttt aagatcggca 11520 acaagttttc ttaaagaaga aacaactgtc tggagtgtcc tcaaatatgc aaggtttgac 11580 ttccctttag caatctccat cacttcttct aacctatttt gaatagactg accaaaaatt 11640 ctttgaaaga aagtttggag aaccaattcg ggattaggga aaacacgttt aatgaccgcg 11700 cagtcacctt ctataacaga acataattca ctaaataaag aagatagtgt ttgaattagc 11760 ggtggtattt tctgcgttgg atctggcaaa atcagccata tagggtcttg ttctaaacct 11820 tgacgagatt gaaccttatc agcagcaatg aagaactcat gctgattaac gaattcacgt 11880 acgacagatg caccaccatt aaactcctga agtatggtgc caaaagatgc catacccttc 11940 caattgggct ttctgtattc gttgttaaaa aattttaaaa aatttgtctc taaaaactcg 12000 gaaaattttt caattcgtgc cagcgtttcg ctcgaatcag gaagatcaac ttcattagca 12060 agcgctaaca attgtcttgt cctttgcgca cataatagca ttttgtcgtg attattggta 12120 cgaaaaaaat ccatgagggt ttgtggtttt ccagaccgaa attccaaata atacctcaac 12180 aattctgctg aagataaaat tcttttacgg ttattttccg cccgttctaa ttcttggcca 12240 gcatcaacta aaccgctgcg catgtcatta acgttatctt ccaaatgcct tgataattcg 12300 aggacctgtg caaatttttc acgtagatga ttagatttct ggtgatactc attttgaact 12360 tgctttgatg ctgaagcata gtcacgtatc ctatcaccaa ctctagactt tagccgattc 12420 aattcatgaa ggcatgccgc aaatgatttg atagacccat caattgaaga tactgaaaca 12480 ttctgttagt aaatcatacc tatataataa aatatgtaac gtatagtatt cgaggtatta 12540 tttttttggg ctattataac tgtgacagaa gtaggaaaac cataaatcga aagtaaaccc 12600 aaaataacaa taagctccag cgattaaaaa aaagcttttg aaatacttag gacacgaatg 12660 aagaggaaat ggtttcgata caaaacaaaa tattaactta cattttttag aaccatcatt 12720 ttgggtctcg taaagggact cagcaaactt ctctacgaac tcggtagaag gaattccttt 12780 ctataatctg ttagttgaga aaagggcaaa aacgggattc ggttacattg tcatttaaag 12840 aatttaataa ctttatctgg gaatcattca acgcgttttt tgtagacatg tcttaataga 12900 caagaaattt taaatctaca attctcgaat agaaaagtaa tgatcaaagt ttcctttggt 12960 ttgtaggtga tgggttatca ctaggttcta tgaagtgggt catagcgaga gcataagtga 13020 aataagtaaa ccgaacgtgt catgagaaac taattaggtc caatttttat ataatggtac 13080 aaactaattg ctcatattta ttttcataat tattttttct actactctga cacagctact 13140 caatatattt taaacataaa ccagatcatc tctagaaaat tgccaaaatc cggtttgatt 13200 caacagacaa aaatatgtaa tttaatcact aagattgtga taaaggatga atttttaaat 13260 agtgaaggat aatacacatt catccttttc ttcgtcatga taagttcttt cataataaat 13320 cgacaaatta aaaaacagaa tgcgattcca cgaacaagca aaaaaaagta aacattttca 13380 atcatcttca taagcttctg atccatcagt aaattcagca tccaaatcgg aatcactgag 13440 gaccgatttt acagttgtgt gatgcctctt gtttttacgt accactttag gaggagagga 13500 agtttttaat ttctgtgaat taacgttcat tttttctccg agctttctac tttcacgttc 13560 atcactttct gaaacatggc cttcattaat tgcatcaaca actttatcaa tccattcttg 13620 tgaaagagcg gtaattccat ctaaactgtt gacaatgtca tcttctccta atctgttttt 13680 tatgtttttt aacattctag gagtaacaca tccccagtgt ttccatgccc aactctgaaa 13740 tctaccagaa tccacaaaag tcccgaatcg tacagttcca gccagtattt ttgacctaaa 13800 tttttgtcag tagaaaagaa atatctctac aatattagac atgtaaatag cgttctgtga 13860 tggtttccaa tcgcctgcca cgaaatcgct aaaaacaaat gaagcaattt tatcgaaagt 13920 accatcagct gtactgaatt tgcgctcata tctcaattgt tttcagttta tgctaaaacc 13980 ttaccgacca cataaagagc ctttgcattt tgcacggttg ttgggtgcaa tttctatgcg 14040 atatccactt ccaccctgtt ccattaatgt gcaatgttcg tactgtaatt tcttcaatac 14100 ttcttaatgt ttcgaattga actgaagata gaataaaatt acaaaactta agtttatttt 14160 atgatcaatc ttgataaatg cagctcctga ttctcaagtt tgtttaaaaa acaatatggg 14220 gattccaaca gatagaaact cgtgatgata tttctcagta gaaagctaat gtccaaaaat 14280 atgaagatat ttcaatatct taaccttaaa attagttcga gggaaatgcc aattttgctt 14340 aatgtcagct ttaaaagaaa ctaagccaat tcttagctat tatagagata ataacaacat 14400 ccccgaatac agtataaagg atatagcgtg taacattgac tcattgaaag ccatgattag 14460 caaacgaaca ccttcttaca gtgtattatc tacatggtgg atgggattgc tacccgatgt 14520 tttgacaaca aggggtgatt ttataccagt aacgtagtag cgtttaattt ctatcaaaag 14580 gaactcttcg atgaaaaaaa cagttgatta aaatcaatat aagtaaataa atcgtgaaat 14640 atcagacctt attctagtta gtatgaagta acttgaatct ttggataaat tttacgcgtt 14700 caatcttgat ctgataattt ttgtcttaca tcatgctaca tagtgtagag ctgggaattc 14760 tagattatac attcaaatct tgtcaaacat ttgcgcttta agagcctttt ttattccttt 14820 catctttaaa gttgtttttt ttttcttttt ttttgaaatt gcaggttctt ttacaatagg 14880 tgctttgtca ggtcttaatc aacattattt ccttttgagc atcttctttt tcattcgttt 14940 atttaaatta aatatatcag gtctcttaat tgattattgt tcctaataac ttggcaagtg 15000 gaccgaaata tcttcatgta ctctgatgat tttccaattg aatttgatcc aatgccaagt 15060 gcttgctact aaaagcgttt agctttaaag atc 15093 //