ID SPAC13A11 standard; DNA; FUN; 12168 BP. XX AC Z54096; XX SV Z54096.1 XX DT 07-SEP-1995 (Rel. 45, Created) DT 18-OCT-1999 (Rel. 61, Last updated, Version 4) XX DE S.pombe chromosome I cosmid c13A11. XX KW cyp51; cytochrome P450; cytosol aminopeptidase; Fes/CIP4 homology domain; KW pyruvate decarboxylase; Rho GTPase protein; Thiamine pyrophosphate enzymes; KW ubiquitin carboxy-terminal hydrolase. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-12168 RA Hunt S., Devlin K., Churcher C.M., Barrell B.G., Rajandream M.A., RA Walsh S.V.; RT ; RL Submitted (06-SEP-1995) to the EMBL/GenBank/DDBJ databases. RL Schizosaccharomyces pombe chromosome I sequencing project, Sanger Centre, RL Hinxton Hall, Hinxton, Cambridge CB10 1RQ E-mail: barrell@sanger.ac.uk XX DR GOA; Q09697; Q09697. DR GOA; Q09735; Q09735. DR GOA; Q09736; Q09736. DR GOA; Q09737; Q09737. DR GOA; Q09738; Q09738. DR SWISS-PROT; Q09697; YA51_SCHPO. DR SWISS-PROT; Q09735; YA55_SCHPO. DR SWISS-PROT; Q09736; CP51_SCHPO. DR SWISS-PROT; Q09737; DCP1_SCHPO. DR SWISS-PROT; Q09738; UBP8_SCHPO. DR SWISS-PROT; Q09739; YA53_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe) CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPAC5H10.01c. CC SP (S. pombe), A (chromosome 1), c5H10 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c13A11 overlapped at the 5' end by comsmid c2F7 and CC at the 3' end c3H8. XX FH Key Location/Qualifiers FH FT source 1..12168 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c13A11" FT /map="IL" FT misc_feature 1..104 FT /note="overlap with cosmid c2F7, positions 42407 42510 FT EM:Z50142 S.pombe chromosome I cosmid c2F7" FT CDS join(complement(385..487),complement(1..340)) FT /db_xref="GOA:Q09697" FT /db_xref="SWISS-PROT:Q09697" FT /label=SPAC2F7.18c SPAC13A11.01c FT /note="SPAC13A11.01c, len:146, SIMILARITY:Saccharomyces FT cerevisiae, YFE7_YEAST, hypothetical 82.2 kd protein in FT EMP47-SEC53 intergenic region, (714 aa), fasta scores: opt: FT 263 E():2.3e-09, (29.5% identity in 146 aa overlap)" FT /partial FT /product="putative Rho GTPase protein" FT /gene="SPAC2F7.18c" FT /gene="SPAC13A11.01c" FT /protein_id="CAA90802.1" FT /translation="MISSFSNGFWSKDYATGVKKLFDCLDNGVEENEQVKNLLKLYKEA FT NEEFGEKLQEITKECLKGKKPENTEDGATSNKAFEGLRSEIANQGKQHIRIAKDLETLI FT IAPFSKMSIDHSQKLQTSQQVLTNQIKSYEKKYYTLKKTKSAY" FT misc_feature join(complement(385..469),complement(144..340)) FT /note="Match to PF00611 FCH, Fes/CIP4 homology domain Score FT 103.18" FT misc_feature complement(341..354) FT /note="ctaacaacgaatag, splice branch and acceptor" FT misc_feature complement(379..384) FT /note="gtattt, splice donor sequence" FT CDS complement(1251..2738) FT /db_xref="GOA:Q09736" FT /db_xref="SWISS-PROT:Q09736" FT /label=cyp51 SPAC13A11.02c FT /note="SPAC13A11.02c, len:495" FT /gene="cyp51" FT /product="probable cytochrome p450 51" FT /gene="SPAC13A11.02c" FT /protein_id="CAA90803.1" FT /translation="MAFSLVSILLSIALAWYVGYIINQLTSRNSKRPPIVFHWIPFVGS FT AVAYGMDPYVFFRECRAKYGDVFTFVCMGRKMTAFLGVQGNDFLFNGKLADLNAEEAYS FT HLTTPVFGKDVVYDIPNHVFMEHKKFIKSGLGFSQFRSYVPLILNEMDAFLSTSPDFGP FT GKEGVADLLKTMPVMTIYTASRTLQGAEVRKGFDAGFADLYHDLDQGFSPVNFVFPWLP FT LPRNRRRDRAHKIMQKTYLKIIKDRRSSTENPGTDMIWTLMSCKYRDGRPLKEHEIAGM FT MIALLMAGQHTSAATIVWVLALLGSKPEIIEMLWEEQKRVVGENLELKFDQYKDMPLLN FT YVIQETLRLHPPIHSHMRKVKRDLPVPGSKIVIPANNYLLAAPGLTATEEEYFTHATDF FT DPKRWNDRVNEDENAEQIDYGYGLVTKGAASPYLPFGAGRHRCIGEQFAYMHLSTIISK FT FVHDYTWTLIGKVPNVDYSSMVALPLGPVKIAWKRRN" FT misc_feature complement(1263..2642) FT /note="Match to PF00067 p450, Cytochrome P450 Score 169.72" FT misc_feature complement(1407..1436) FT /note="PS00086 Cytochrome P450 cysteine heme-iron ligand si FT gnature" FT CDS join(4637..4702,4797..5363) FT /db_xref="SWISS-PROT:Q09739" FT /label=SPAC13A11.03 FT /note="SPAC13A11.03, len:210, SIMILARITY:Arabidopsis FT thaliana, CAB43931, hypothetical 14.7 kd protein., (128 FT aa), fasta scores: opt: 236, E():2.7e-08, (37.5% identity FT in 120 aa)" FT /gene="SPAC13A11.03" FT /product="hypothetical coiled-coil protein" FT /protein_id="CAA90804.1" FT /translation="MPPKGLSLAEKRRRLEAIFHDSKDFFQLKEVEKLGSKKQIVLQTV FT KDVLQSLVDDNIVKTEKIGTSNYYWSFPSDAKRSRESVLGSLQAQLDDLKQKSKTLDEN FT ISFEKSKRDNEGTENDANQYTLELLHAKESELKLLKTQLSNLNHCNPETFELKNENTKK FT YMEAANLWTDQIHTLIAFCRDMGADTNQIREYCSIPEDLDDLQLPIL" FT misc_feature 4703..4708 FT /note="gtaagt, splice donor sequence" FT misc_feature 4775..4796 FT /note="ctaatctatgttttttttatag, splice branch and acceptor" FT CDS join(complement(7411..7506),complement(7200..7332), FT complement(6412..7099),complement(6069..6366), FT complement(5951..6015),complement(5836..5905)) FT /db_xref="GOA:Q09738" FT /db_xref="SWISS-PROT:Q09738" FT /label=SPAC13A11.04c FT /note="SPAC13A11.04c, len:449, FT SIMILARITY:Schizosaccharomyces pombe, O74442, ubiquitin FT carboxyl-terminal hydrolase, (457 aa), fasta scores: opt: FT 536, E():3.1e-27, (30.6% identity in 320 aa)" FT /gene="SPAC13A11.04c" FT /product="ubiquitin carboxyl-terminal hydrolase" FT /protein_id="CAA90805.1" FT /translation="MPGDVEGCQHLKLKPADVENYQKICTQIFSCHFVPRRCSTCKRIN FT KRSIRCLSCHSVGCLWGHHGEEHAMEHTHMIGVDVKNGHTYCFGCQDYVYQTELETLRF FT KIKNIKAWQSDHKRLPEKYNQMVCLEAYRKYPPVCATAGLRGIQNLGATCFMSVILQSI FT LHNPLVRNLFFSGFHTSTDCKRPTCMTCAIDDMFSSIYNSKNKSTFYGPTAVLNLMWKL FT SKSLCGYSQQDGHEFFVYLLDQMHTESGGGTSMPCTCPIHRIFSGSLKNVVTCLDCKKE FT RVAVDPLMDISLDINEPTLQGCLERFVSKEKVQYSCHSCGSKNAIKQLVFDKLPPTICM FT QLKRFEQNNFAMSTKIDKQVSYPAFLRMRYNFNQDDVDYQLYSVVCHKGTLDTGHYIAY FT TYYQNQWFLLDDTTIVEVKESEVLNSQAYLLFYHERQILYSDEMTVKTEN" FT misc_feature complement(5906..5920) FT /note="ctaaccagattatag, splice branch and acceptor" FT misc_feature complement(5945..5950) FT /note="gtaggc, splice donor sequence" FT misc_feature complement(6016..6028) FT /note="ctaatttttgtag, splice branch and acceptor" FT misc_feature complement(6063..6068) FT /note="gtatat, splice donor sequence" FT misc_feature complement(6069..6149) FT /note="Match to PF00443 UCH-2, Ubiquitin carboxyl-terminal FT hydrolases family 2 Score 53.18" FT misc_feature complement(6367..6385) FT /note="ttaacaaatattattttag, splice branch and acceptor" FT misc_feature complement(6406..6411) FT /note="gtaaaa, splice donor sequence" FT misc_feature complement(7018..7071) FT /note="Pfam match to entry PF00442 UCH-1, Ubiquitin FT carboxyl-terminal hydrolases family 2" FT misc_feature complement(7100..7110) FT /note="ctaattcttag, splice branch and acceptor" FT misc_feature complement(7194..7199) FT /note="gtacgt, splice donor sequence" FT misc_feature complement(7261..7278) FT /note="PS00190 Cytochrome c family heme-binding site signat FT ure" FT misc_feature complement(7333..7352) FT /note="ttaacatttctttcatttag, splice branch and acceptor" FT misc_feature complement(7405..7410) FT /note="gtaagg, splice donor sequence" FT CDS 8608..10149 FT /db_xref="GOA:Q09735" FT /db_xref="SWISS-PROT:Q09735" FT /label=SPAC13A11.05 FT /note="SPAC13A11.05, len:513, SIMILARITY:Bos taurus, FT AMPL_BOVIN, cytosol aminopeptidase, (487 aa), fasta scores: FT opt: 1008, E():0, (42.1% identity in 442 aa)" FT /gene="SPAC13A11.05" FT /product="cytosol aminopeptidase" FT /protein_id="CAA90806.1" FT /translation="MKGLGLSTRTFNWSSLSSILLPRIPLATTKADSLILAVRHDKQVF FT SEDYRQVVDQYFETSPKKNDIRLFWNTQGFVRLAIVQLEENVSEKSVRSAAAEAAKILK FT SNGAKSIAVDGMGFPKDAALGAALATYDFSLRRDHLSVYQDEKVVEKENLFTSPAPERL FT TFQLLSNTSEKKTATAEENAFKVGLIEAAAQNLARSLMECPANYMTSLQFCHFAQELFQ FT NSSKVKVFVHDEKWIDEQKMNGLLTVNAGSDIPPRFLEVQYIGKEKSKDDGWLGLVGKG FT VTFDSGGISIKPSQNMKEMRADMGGAAVMLSSIYALEQLSIPVNAVFVTPLTENLPSGS FT AAKPGDVIFMRNGLSVEIDNTDAEGRLILADAVHYVSSQYKTKAVIEASTLTGAMLVAL FT GNVFTGAFVQGEELWKNLETASHDAGDLFWRMPFHEAYLKQLTSSSNADLCNVSRAGGG FT CCTAAAFIKCFLAQKDLSFAHLDIAGVMDKQLNSWDCDGMSGRPVRTIIEVARKY" FT misc_feature 8743..10047 FT /note="Match to PF00883 Peptidase_M17, Cytosol FT aminopeptidase family Score 764.41" FT misc_feature 9685..9708 FT /note="PS00631 Cytosol aminopeptidase signature" FT CDS 11713..12168 FT /db_xref="GOA:Q09737" FT /db_xref="SWISS-PROT:Q09737" FT /label=SPAC13A11.06 SPAC3H8.01 FT /note="SPAC13A11.06, len:151, FT SIMILARITY:Schizosaccharomyces pombe, O42873, putative FT pyruvate decarboxylase, (570 aa), fasta scores: opt: 709, FT E():0, (71.2% identity in 153 aa overlap)" FT /partial FT /product="pyruvate decarboxylase" FT /gene="SPAC13A11.06" FT /gene="SPAC3H8.01" FT /protein_id="CAA90807.1" FT /translation="MSGDILVGEYLFKRLEQLGVKSILGVPGDFNLALLDLIEKVGDEK FT FRWVGNTNELNGAYAADGYARVNGLSAIVTTFGVGELSAINGVAGSYAEHVPVVHIVGM FT PSTKVQDTGALLHHTLGDGDFRTFMDMFKKVSAYSIMIDNGNDAAEKI" FT misc_feature 11755..12162 FT /note="Match to PF00205 TPP_enzymes, Thiamine pyrophosphate FT enzymes Score 168.62" FT misc_feature 12046..12168 FT /note="615 (+1) 1 123 SPAC3H8 EM:Z69086 S. pombe FT chromosome 1" XX SQ Sequence 12168 BP; 3926 A; 2206 C; 2256 G; 3780 T; 0 other; tagtaagcgc tttttgtttt tttaagtgta tagtatttct tttcataact ctttatttga 60 ttggtaagaa cttgttggct ggtttgtaac ttctgagaat gatcaataga cattttagag 120 aaaggagcaa taattagcgt ttctaagtcc ttggcaatac gaatatgttg ctttccttga 180 ttagcaatct cggagcgcaa cccttcaaaa gccttgttag aagtagcacc gtcttctgta 240 ttctctggct ttttcccttt tagacattct ttcgttattt cttgaagctt ttcaccaaat 300 tcctcattcg cttctttata taacttcaac aagtttttta ctattcgttg ttagaggaag 360 tcctatatta atttatttaa ataccttgct cattctcttc aactccatta tccaggcaat 420 cgaaaagttt tttcacacca gtcgcgtagt ctttactcca aaaaccattt gaaaagctcg 480 atatcatttc aattcgagac tgaaactgtc acaacctgtc aagaaatata gaggtggttg 540 acatgtctac gccctttatt actcaactta agtaaatagc gaattgctac gcagaaaagt 600 tttacccatc aaggatgcca aaagtatcca gtaaataaga caacagatac gttacttgac 660 acacataaga tagcatacca ctaatccttt ataaaatgta aacttcattc agttgaatag 720 cagcctacgc ttttacccac tttgtattat taatgctatg gttggatcga tggtacaatt 780 aaaaactaca aaattttaat taatagctta ctgagaaacc ttgcgtttgc acgatgaggt 840 tttgaaaaga gagagtagcg tactttattg ttataatgcc tacatgaaaa cgaaagagag 900 cgtcccgacg ttattaaaac tataatatcg taaaaatgta tcactaatga tgacagggta 960 gttttcatat cgatttagtg cgaggataag gaagtttgaa attgcataat acattctttt 1020 gacatttgaa atgctaccaa atagtcattt aaaacgctaa aatatttaca atttcataaa 1080 acaataaagc acttaaaatt taaaatgtct agcaaatttc atggttattc gttactcgtc 1140 agataaaaca aaaacgttta acacgggcat gaaaagagaa aggcggaacc aaagttagaa 1200 accaatacca taagcgtatt gcaaatgcat tcaaattagg ggaaattccc ttaattacga 1260 cgcttccaag caattttaac aggacccaag ggaagagcaa ccatactgga atagtcaacg 1320 ttgggaactt ttccaataag agtccaggtg taatcgtgta caaacttgct aataatagtg 1380 ctcaaatgca tgtaggcaaa ttgctcacca atgcaacgat gacgaccagc tccaaagggt 1440 aggtatggag aagcagcacc ctttgtaacg agaccataac cataatcaat ttgctcagca 1500 ttttcgtctt cattgacgcg gtcattccag cgcttggggt caaagtcagt agcatgagtg 1560 aagtattcct cttcagtagc agttaaaccg ggagcagcaa gaagatagtt gttggcaggg 1620 ataacaatct ttgaaccagg gacgggtaag tcacgtttga ctttacgcat atgactgtgg 1680 atagggggat ggagtctaag agtttcttga ataacatagt tgagaagagg catgtcctta 1740 tattggtcaa acttcaattc caagttttca cctacaacac gcttctgctc ttcccacaac 1800 atttcaatga tttcaggttt gctacccaaa agagcaagaa cccaaacgat agtggcagca 1860 gaggtgtgtt gaccagccat caaaagtgca atcatcatac cagcaatttc atgttccttc 1920 aaaggacggc catctctata cttgcagctc atcaaagtcc aaatcatatc agtaccagga 1980 ttttcagtgc tagagcgacg atctttaata attttaagat aagttttttg cataattttg 2040 tgggctctat cacggcgtct gtttctaggg agaggtaacc aagggaaaac aaagttaaca 2100 gggctaaatc cttgatcaag gtcatggtac aagtcagcga aaccagcgtc aaagcccttg 2160 cgaacctcag caccttgtaa agtacgagaa gcagtgtaaa tagtcatgac aggcatggtc 2220 ttcagcaaat cagcaacgcc ttccttacca ggtccgaagt caggagaagt gctgagaaaa 2280 gcatccattt cgttaagaat gagggggaca taagagcgga attgagagaa gccaagacca 2340 gatttgataa acttcttgtg ctccataaaa acatggttgg gaatatcgta aacgacatct 2400 ttaccgaata caggggtagt taaatgagag taagcttctt cagcattcaa atcagctaat 2460 ttaccgttaa agaggaaatc attaccttgg acaccaagga aagcggtcat tttacgaccc 2520 atgcaaacaa aggtgaaaac atcaccatat ttggcacgac actcgcgaaa aaatacataa 2580 gggtccatac cgtatgcgac agcagaacct acaaagggta tccaatggaa gacaattggg 2640 gggcgtttgc tattgcgaga ggtaagttgg ttaataatat aaccaacata ccaagccaat 2700 gcaatcgata ataaaatcga aactaaagag aatgccatcc tgacttatga aaaaaaaagt 2760 aatgctcaag tgggtaaagc aggtaaaaaa taatcagacg aaaaaaataa aatcagtcag 2820 taaagtagta aggggtaagc agatagcaac caaaaacgaa taagaccaac caaaaaacaa 2880 cgacaacaac aacaaatgtg taacagataa aaatagttca accctttgag ctaatgcaaa 2940 taaacttgaa aaagaaaagg agaaagaaaa aatgaattga ttaacacgca gctacgagaa 3000 caacgaatga aacaaataga aaaaagcgtt aaaaacgaaa tcgaaaacag acaataatat 3060 gaaagaaaaa caaaaaaaaa ttacgtttcc tttcacttaa cgaatgagat tgggattttg 3120 aaaagacaat tttcaaaaac aacgatcgat acagaaattt tagatcttgt cttttttaag 3180 gtacttctac aagtgaagaa tcgatttatc ttctctttga caccaaatac gctggtttcg 3240 acgacgattc aagctaactt gggtctcgcg ctgactgatg ggagttggta gaattatata 3300 tgcaacataa tggccgtgta accgtttgtt tatgctgaaa atccgtaaaa aaacatgcta 3360 cttgatcact tcaaaattac acttttttat ccaatcatat ttttcagata ctaccttatt 3420 gttctttctg gtcaaggtga attagccact aagccaatga gaaatccaat tttgttacct 3480 gagaataggg cgacatcgta cgattcgagg gtttgtgagg tgaatgactg cggggcttat 3540 gttgcgatcg aacgatggca cgtccattgg accgagataa tacacatgtt taccgtagct 3600 cgtaacgcac atttaacaaa ctacttgctt ctaccctact ttatcaccta aaaataaaaa 3660 tgtgtcaaca tgtgcacgtc tactatacct tctactattt gttcggtaaa ccaccaaccg 3720 tgcctcctta tacgtcttct ccaaacatgt aattggattc gaacaacttt agctcgacaa 3780 gtcgtttagc ttacgaacat ccaaaagctt atctaatgac ctaactaact cgctcttttt 3840 ggtcgcatga ctttgcatac gattgtttag taataaaaac aataatcctt ttcacacctg 3900 tttttaccca tgggaaagcg gttcccaaag tttgtcactt actcccatat tctaatctag 3960 attaaaacac atttagctgc gaacatggca caccggttaa tacccagcca tagttgaaat 4020 tagtagacaa attgactgag tatctcttat caaaagtcaa tacacatttt gtttgcgctg 4080 acattaaaca tcgttgctct tatgaatgct atgtgtgtgt gtgtgtgtat gtggaaatgt 4140 gttagtcagt cagtgtttgc ttgaaattcg ctgtgtgaaa ataataaagt gaaaaataaa 4200 taaaaggttg taaaaccgaa ttcgtacagt aaggtgagcg ccgacaaaag ctcttgagaa 4260 aaaaaaaatc atgctgctat cagtattcga gtcttttcga tttcgtggca aaaggaagtt 4320 ttcctcacat gtttttgtgc gacaatagcc aaccccattc acttaattcc ttaatttcct 4380 caagggtcaa aaagattagg atagctgaat aacgttttgc attgcattat gttgcaatac 4440 gatagtaaga cattataggg tatatatcat agttggaaag tgcggatgtg cattttagca 4500 gactacgtta tcattcagta aatgtttggg atctaaactc tcatttctcc aaaagattag 4560 aaagcatcta cttcttgcat cacaacaaac ttttaaactc catatttgtt caaactaatt 4620 aataaatttt taaacaatgc ctcccaaggg actatcgctt gcagagaaaa gaagaagatt 4680 agaggccatt ttccatgact ctgtaagttc gtgatatgat tgttcaagtg ccaaaacatg 4740 atttttgccc attcgtgtct cactttccac attgctaatc tatgtttttt ttatagaaag 4800 atttttttca actaaaggag gtggaaaagc tgggctctaa aaagcaaatc gttttgcaaa 4860 ctgtaaagga cgttttacag tctctcgttg acgacaatat cgtcaaaacg gaaaagattg 4920 gcactagcaa ttactactgg tcttttccct ccgatgctaa acgttcaaga gagtcagttc 4980 tcggatctct tcaagctcaa cttgatgatt tgaaacaaaa atctaaaact ttagatgaaa 5040 acattagttt cgagaaatcc aaaagggata acgaaggaac cgaaaatgat gccaatcaat 5100 acactttgga actgctacat gcaaaagaat cagaactaaa acttcttaaa acacaacttt 5160 caaatttaaa tcactgtaat cctgaaacct ttgaattaaa aaatgagaat actaaaaagt 5220 acatggaagc tgccaatttg tggaccgatc aaatccatac tttgatagct ttttgtcgag 5280 acatgggtgc cgataccaat caaattcgtg agtattgcag cattccagag gatttggacg 5340 atctgcaact accgattttg tgaacttgac atgcttcctt aattcaaaga gttgttttcc 5400 ttattaatat tttaaaattt tatacatttt aacagttaca tataaaatag cttactcgac 5460 gacaagactt agcttttaaa agataaaatt ataattagtt ggaataatat taaacgaaac 5520 aaaacaaaag tccaaattcc tcaaacttat agtatttgtt aactttgaaa gaaaaaaagc 5580 atgtttcttt ttttatagtt ttaacttttt ttataaattt acgtaaggtc attaattaaa 5640 atgcgactgt tgtaacggtt ccaaatccaa tgccatttct ggcctcaaca atatgaaatc 5700 taaaagcttc ttcatgagtt agattatcga agtgatgatg tttcataacc acataaataa 5760 ggaacctttg agtcaattac tttacatggt tcataatgat tgttcatgaa cggatatctg 5820 atcgcataat ctaactcaat tttccgtttt aacagtcatt tcatcactgt ataggatttg 5880 acgctcatgg taaaataata ggtaactata atctggttag tatgtaaaaa aataacagca 5940 aagagcctac gcttgagaat ttaagacctc cgattccttt acttccacaa ttgtggtgtc 6000 atccagcaaa aaccactaca aaaattagta aaaatttcca taaaaaattc aaaaaaaatt 6060 taatatactt gattttggta gtatgtatag gcaatatagt gccctgtgtc gagagttcct 6120 ttatgacaca caactgagta taattgataa tccacatcat cttgattaaa gttgtagcgc 6180 attcttaaaa atgctggata agatacttgc ttatctattt tagttgacat ggcaaagtta 6240 ttttgttcaa atcgtttcaa ttgcatgcaa atagttggag gtagtttgtc aaagaccaat 6300 tgtttaatag cattttttga cccgcaacta tgacagctat attgaacttt ctctttggaa 6360 acaaacctaa aataatattt gttaaaaaat ctaaaaacga gcaaatttta cctttccaaa 6420 catccttgaa gtgttggctc attgatgtct aaactaatgt ccatcaaagg atccacagcc 6480 acccgctcct tcttgcaatc taggcatgta acaacgtttt tcagagatcc actaaaaata 6540 cgatgaatag gacaagtgca cggcattgat gttcctcctc cgctttccgt atgcatttgg 6600 tccagcaagt atacaaaaaa ttcgtggcca tcttgctggg agtaaccaca taaagatttg 6660 ctgagtttcc acataagatt taagacagca gtgggaccgt aaaaagtaga tttgttttta 6720 gaattataaa tagatgaaaa catatcgtca atggcacaag tcatgcaagt aggtcgctta 6780 caatcagtag aagtatgaaa cccactgaaa aacaagtttc gaaccaatgg attatgcaaa 6840 atactttgta aaatgacgct catgaaacaa gtagcaccca agttctggat ccccctcaag 6900 cctgctgttg cgcaaactgg agggtatttt cgataggctt ctaagcaaac catttgattg 6960 tacttctcgg gaagtctctt gtgatcactt tgccatgcct tgatattctt gatcttaaaa 7020 cgaagggttt ccaactcggt ctgataaacg tagtcttgac agccaaagca gtaggtatgg 7080 ccatttttta catccacgcc taagaattag taattggtat tcgggaattg catcctaact 7140 cgatattcgc aaaaaggttt cgttgctaaa tcaatagcta tgttttcaac taaacgtacc 7200 gatcatatga gtgtgctcca ttgcgtgttc ttcaccatga tgtccccaaa gacatcccac 7260 agaatgacaa ctcaagcatc gaatactccg cttgttgatg cgtttgcaag tactgcagcg 7320 acgtgggaca aactaaatga aagaaatgtt aaaaggaatc gaatggaaaa agaaaattga 7380 actgtatgaa gtgttgttca caagccttac atgacaactg aatatctggg tacagatctt 7440 ttgatagttt tcaacatccg ccggtttaag tttaagatgc tggcaacctt ctacatcccc 7500 aggcatcctt gatacgtaca aaattggcct ttcagactaa aaagcatctg cttcgatgca 7560 gggtgaaacg acaacaatag acgaactcgc tattctggca aaagaacatt atttctcttt 7620 gcttaaattt gggcaattaa ggatgcggtg tacagcgtta agagccataa agtactcata 7680 gtgtctgcac tactagatac cgatttcgta taaagagcta tcatagctac gctaagtcaa 7740 ttgataaaac accaaaatag atgttcttcg tagttcttga gtgtccttgg ttttcctctt 7800 taaaacataa acttggtaaa ttcccataga tttggctgtt gagtcactgc aaaataaaaa 7860 aaattactgc tagtccttta atcacggttg aatagatgaa attgttaatt ttttaaaagc 7920 ttggtcaaat tagactaatg cctctattaa cgtcgaacgt gtttaagtgt acgcttatgt 7980 ttgttgccat gaaacgtttg cagggctaaa tataaaacca tatatgacta tttaccgtga 8040 gcatctttgt aatacaaccg agtcactgca agcaggtaca tgtacgaaaa tttttgtcta 8100 ttacatttgt atagaattta ttacttaaca attgactagg ggcagatttt tgtgccgaaa 8160 cagtttgtgt taccctaaat agagattgta gggcaacaat acgtctgcag aagttcaaat 8220 atatatgtag caaatgagtg tgacttactt aaaaattggt ttttgatcaa gaaataaaat 8280 cctttggtgc tttttctttt ttatgtctag ccttgttgaa tgtatttttc catcacaatg 8340 ttgatcttgt ctactcaata acacactaga ctatgttaag tacacttgcc cttgcccaat 8400 ctgcaatcgg acatcgtatt ttatttttgc atactgaatt tacgtgtatt cgtagtttca 8460 cgagttaacg attttcgaat atccaactct cattgaactt ataataatcc gtaatccttt 8520 accttttttt tgattacaag tgtctaatta agttttctaa atcaagagaa atcaaagata 8580 caagcaaagc tttttttctt acgtacaatg aagggtttag gtctaagtac gagaaccttt 8640 aattggagct cactttcttc cattctttta ccaagaattc ctttagctac tacaaaagcc 8700 gattccttga ttttggctgt tcgtcacgat aaacaagttt tttctgaaga ttatcgacaa 8760 gttgttgacc agtattttga aacatctccc aaaaaaaatg acattcgtct cttttggaac 8820 actcagggtt ttgttcgtct tgccatagtc cagcttgaag aaaacgtttc tgaaaagtcc 8880 gttcgttcag ctgctgcaga ggcagctaag attttaaagt cgaatggtgc aaagtcgata 8940 gctgtcgatg gtatgggttt tcccaaggat gctgccttgg gtgctgcctt ggccacgtac 9000 gatttttctc ttcgtagaga ccatttgagc gtctatcaag atgaaaaggt ggttgaaaag 9060 gaaaatttat ttacctctcc tgctcctgaa aggttaactt tccaattgct tagcaacaca 9120 tctgagaaga aaactgcaac cgcagaggag aatgctttta aggtaggttt gattgaagca 9180 gctgctcaaa acttggctcg ttctcttatg gaatgtcctg ctaattacat gacttctctt 9240 caattttgtc attttgctca agagttattc caaaattcct caaaggttaa agtattcgtt 9300 cacgatgaga agtggattga tgagcaaaag atgaacggtt tacttaccgt gaatgctggt 9360 tccgatattc cacctcgttt cttagaagta caatacattg gtaaagaaaa atcaaaagat 9420 gatggatggc ttggtttagt tggaaaaggt gtaacgtttg acagcggtgg tatcagtatc 9480 aagccttctc aaaacatgaa ggagatgcgt gctgatatgg gtggtgctgc tgttatgctt 9540 tcctctattt atgccttgga acaactttcc atccccgtga atgccgtgtt tgttacccct 9600 ttaactgaga atcttccttc tggctctgct gctaagccag gagatgttat ttttatgcgc 9660 aacggtctta gtgtagaaat tgataacact gacgctgagg gtcgtcttat tcttgccgat 9720 gcagttcact atgtctcttc tcagtataag accaaggctg tgattgaagc cagcacatta 9780 actggtgcta tgctagtagc cctcggtaat gtatttactg gtgcatttgt tcaaggagaa 9840 gagttgtgga agaatcttga aactgcttcc catgatgctg gagacctttt ctggcgtatg 9900 ccatttcacg aggcttacct caagcaactt acaagttctt caaatgctga tttgtgcaat 9960 gttagtcgtg ccggtggtgg ttgttgtaca gcggctgcct ttattaaatg cttcttagcc 10020 cagaaagatt tgtcttttgc tcatttagac attgccggag ttatggataa gcagcttaat 10080 tcttgggatt gtgacggcat gagcggacgc ccagttcgca ctattattga agtcgctcgc 10140 aagtattagc ttatttattt tcttggctat atgtgcaaac tttatgtttt tacttattta 10200 ctgttgatta caccaatctc atttttcaat gtccttgtta agtgtatgtc aatgatatgt 10260 agctatcatg attttattct ttttaatact gttttccaca accgttcata acggttgtaa 10320 ggaccgagtc tttctgatgg ctctggttct gtttccttta aaaataaaat caattcggtt 10380 gaagtctcat gttgttaaat ttcactttcg aagtagcgaa tttttttttt ctattttgaa 10440 tatagatttg tttattaaat gtagtaatca atttactcat gactattact tttgtcaaac 10500 aaaatcataa tacaaaacta aatctttaaa ggtagaatat tctcctgtgc gagtttacaa 10560 tactttggga tatgatcaaa tcaatttttt ttagatatct gttgaaattt ttataacagt 10620 aattttgtat tatttatcat actatttatt agcgttacct gccctcttaa atgtacacat 10680 catgtggggg tgggggaacc agtgctggag atcacttctt gctataccgt ttggctcatg 10740 gcaactattg aggatagcaa ggagcgttac aatttgcaaa tcaatatgat aaacagaaaa 10800 acaacaagtt gaagcttaac actgtagcaa tataacaatg aaaaaaataa tcagaattaa 10860 agcaagaagc ctataaatgg tccatcaatt gtgaaatcga tattgctaga tgtcaggcaa 10920 atcgtgaact cggttgaaaa atgtcgttaa tattcatgtg aaatcataat tacagcaata 10980 tgttcaaaga cttttggata ctttataata atgaggattc tatttttgag tggtcacatg 11040 gtctcgtaac catgaggtac gccttacttt tacggacgaa acaatatttc acattcagct 11100 ctcaatgtta agtatccaaa caaacatggt acaaaccaat aaagcatgta aattaataag 11160 cttgaaataa ggaatagtca ttaaattcag tttagacata atgtaaaagg tatcaatttt 11220 gtctttggta tagatacaat taagaatttc gagacggaac gttcggtgat gtagagtttt 11280 cataataatt tctgcagttg cttacactaa ccgaagaatc gtccagtata aactgctgac 11340 gatgccttaa atcaataatt gcaaattgca tagttgacgt tttcccgggt ggcacatagt 11400 gagatttgag tcgaataatg aaatagcctc tgacgagtgg tttcgtacca agagtttcaa 11460 aaagaataat ccacattaac tcaatgtatc attgatgacg gaatgttgct tatatagcca 11520 gagtaaccct gctctgaagc atctaaggtt atatcttttt aacttttagc tagcaaactc 11580 acttgttcct ttaagttcag aaagtatctg ctggttattc aacagataat tatcttgcga 11640 aaaaggaata cacactcagc attgtaattt gttgagtata tttcacaagc acattaaatt 11700 gcattatcaa acatgagtgg ggatatttta gtcggtgaat atctattcaa aaggcttgaa 11760 caattagggg tcaagtccat tcttggtgtt ccaggagatt tcaatttagc tctacttgac 11820 ttaattgaga aagttggaga tgagaaattt cgttgggttg gcaataccaa tgagttgaat 11880 ggtgcttatg ccgctgatgg ttatgctcgt gttaatggtc tttcagccat tgttacaacg 11940 ttcggcgtgg gagagctttc cgctattaat ggagtggcag gttcttatgc ggagcatgtc 12000 ccagtagttc atattgttgg aatgccttcc acaaaggtgc aagatactgg agctttgctt 12060 catcatactt taggagatgg agactttcgc actttcatgg atatgtttaa gaaagtttct 12120 gcctacagta taatgatcga taacggaaac gatgcagctg aaaagatc 12168 //