ID SPAC1039 standard; DNA; FUN; 27893 BP. XX AC AL133521; XX SV AL133521.1 XX DT 15-DEC-1999 (Rel. 62, Created) DT 15-DEC-1999 (Rel. 62, Last updated, Version 1) XX DE S.pombe chromosome I cosmid c1039. XX KW 2,2-dialkylglycine decarboxylase; amino-acid permease; KW Aminotransferases class-III; Bacterial transferase hexapeptide; C2H2 type; KW esterase; family 31 glucosidase; Glycosyl hydrolases family 31; isp5; KW pyridoxal-phosphate; serine acetyltransferase; KW sexual differentiation process putative amino-acid permease isp5; sugar_tr; KW translation initiation inhibitor; transporter; UPF0076; zf-C2H2; KW zinc finger protein. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-27893 RA Hunt C., Aves S., McDougall R.C., Rajandream M.A., Barrell B.G.; RT ; RL Submitted (13-DEC-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk and Department of Biological Sciences, University of RL Exeter, Perry Road, Exeter EX4 4QG, United Kingdom XX DR GOA; P40901; P40901. DR GOA; Q9US33; Q9US33. DR GOA; Q9US34; Q9US34. DR GOA; Q9US37; Q9US37. DR GOA; Q9US38; Q9US38. DR GOA; Q9US39; Q9US39. DR GOA; Q9US40; Q9US40. DR SPTREMBL; Q9UR06; Q9UR06. DR SPTREMBL; Q9US31; Q9US31. DR SPTREMBL; Q9US33; Q9US33. DR SPTREMBL; Q9US34; Q9US34. DR SPTREMBL; Q9US35; Q9US35. DR SPTREMBL; Q9US36; Q9US36. DR SPTREMBL; Q9US37; Q9US37. DR SPTREMBL; Q9US38; Q9US38. DR SPTREMBL; Q9US39; Q9US39. DR SWISS-PROT; P40901; ISP5_SCHPO. DR SWISS-PROT; Q9US40; YFZ1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1039 is overlapped at the 5' end by cosmid c29B12, EMBL CC entry SPAC29B12, accession number Z99164 and at the 3' end by CC cosmid c922. XX FH Key Location/Qualifiers FH FT source 1..27893 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1039" FT /map="IR" FT misc_feature 1..49 FT /note="nominal overlap with cosmid SPAC29B12 S. pombe FT chromosome 1" FT CDS 1375..3078 FT /db_xref="GOA:Q9US40" FT /db_xref="SWISS-PROT:Q9US40" FT /label=SPAC1039.01 FT /note="SPAC1039.01, len:567, SIMILARITY:Schizosaccharomyces FT pombe, O74537, putative amino-acid permease., (557 aa), FT fasta scores: opt: 2304, E():0, (62.5% identity in 520 aa)" FT /gene="SPAC1039.01" FT /product="amino-acid permease" FT /protein_id="CAB63537.1" FT /translation="MSSIMEKTDVSSSKHSFTFEPSSDEVGKAAEIVDTHENFYDDQGD FT IDNPEELAELGYKQEFRRQLSLFGIFSISFSVLGMLPSVASTLVFGLWYVGYPGLLWAW FT LIAMFFLICVSMSMAEICSAMPTSGGLYYAAAVFAPKGWGPLASWITGWSNYIGNIIGQ FT PSVNSSAASMILGAVTVNRPDFVIQRWQWFLLAVAIQCFNCVLACLPTRIISRINGVAT FT YLNTAFLFIAGITILAYGGKNHNFVKGTKIWGDYINTTQWPTGFAILLSFNSPIWTMSG FT YDAPFHLSEECSNASVNAPKAIVMTAVIGGVVGWIMQIIVAYTLTDIDSVMNTSGSMWT FT AYLVQAMPPKAALGILSLTIISAIIMGQSALIASSRIAYSYARDGILPFSGWIGTVNPY FT TQTPVNAVICNCIISILILFLTFAGTVTLDAVFSVGAVAAFIAFTVPIAIRVFFTKDAD FT FRRGPWNLGKFSRPIGLLAVSFVALMIPILCFPSVKNPTAQEMNWTCLVYGGPMLFTLV FT WYAISARKWFKGPKASAHYKRPGEESSDIVEGVQADIPSSSDQLKIKGDL" FT misc_feature 1543..2964 FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease," FT CDS 5742..7547 FT /db_xref="GOA:Q9US39" FT /db_xref="SPTREMBL:Q9US39" FT /label=SPAC1039.02 FT /note="SPAC1039.02, len:601, SIMILARITY:Schizosaccharomyces FT pombe, O13781, hypothetical 71.4 kd protein c17g6.03 in FT chromosome i precursor., (635 aa), fasta scores: opt: 936, FT E():0, (37.7% identity in 605 aa)" FT /gene="SPAC1039.02" FT /product="hypothetical protein" FT /protein_id="CAB63538.1" FT /translation="MKLSSLPSGLGLASLLGLISSATAYSATDLTTMYDWNQIIKPLEW FT GQLNFIHTTDTHGWLGGHLRDARYKADFGEFKSFALRMKELADFKGVDLLMVDTGDLHD FT GNGLSDASDPQGIYTNNIFTYLPYDILTIGNHELYQAAISNNTHEYFVPHWNGTYLASN FT VQIYNSSNELEQFGGESTYFITKHGVRTLAMGFLFNFSSNANNTVVTPVETAIKSEWYQ FT QQINRTDVDLFLLIGHIPVRDYDEWKSLHASIRKVHPNTPIQILGGHSHIRDFAVYDEA FT SVSLEGGRYCETVGWLSIDGLSASNATRQYVGRPVTNETRQSYPNLPKPATPLYYTRRY FT IDFNRQNFRFHTQQSEDSFDTPEGVELSKVIKQYRDDLNLSYVFGCIPKNYYMTEVSPQ FT AEDSIFKLMVDHILPEVLVNENRSSVPHIIISNGGGVRGSMYEGTFGPDEMFQLNPFLT FT NYYNYIPDVPYKYAKKLYSILNGGSTLRNVNDYLAALNPGYVTSDDFGEDGDDTVHTYV FT STYAVPNVLQAQVGFNTTSAPETVDVVFLNYFQTKVLKALNTMVNETIYTLSNVTQYWV FT REDGKDSSPYMFAQYVQQEWSDYCD" FT CDS 8754..9779 FT /db_xref="GOA:Q9US38" FT /db_xref="SPTREMBL:Q9US38" FT /label=SPAC1039.03 FT /note="SPAC1039.03, len:341, SIMILARITY:Petroleum-degrading FT bacterium hd-1., Q9XDR4, esterase hde., (317 aa), fasta FT scores: opt: 545, E():6.9e-28, (33.7% identity in 309 aa)" FT /gene="SPAC1039.03" FT /product="putative esterase" FT /protein_id="CAB63539.1" FT /translation="MSQTTTETIIPLDSSVKDKLDPEYVNFYNKYVCSNLPIVKTHTYP FT VDFLRNNGNVMPGQSELLPVESTEDITIPRKHTKAPSGVPSRIFRPHGTAPEGGWPCFL FT WFHGGGWVLGNINTENSFATHMCEQAKCVVVNVDYRLAPEDPFPACIDDGWEALLYCYE FT NADTLGINPNKIAVGGSSAGGNIAAVLSHKVAASPANFPPLVLQLLVVPVCDNTANAKT FT HKSWELFENTPQLPAAKMMWYRRHYLPNEKDWSNPEASPFFYPDSSFKNVCPALICAAG FT CDVLSSEAIAYNEKLTKAGVESTIKIYEGCPHPVMAMDAVLEKGRILNKDATNALLAAF FT A" FT CDS 10926..12449 FT /db_xref="GOA:Q9US37" FT /db_xref="SPTREMBL:Q9US37" FT /label=SPAC1039.04 FT /note="SPAC1039.04, len:507, SIMILARITY:Schizosaccharomyces FT pombe, YAOI_SCHPO, putative transporter c11d3.18c., (498 FT aa), fasta scores: opt: 853, E():0, (30.7% identity in 512 FT aa)" FT /gene="SPAC1039.04" FT /product="putative transporter" FT /protein_id="CAB63540.1" FT /translation="MEKSISSISKASMNSDEKLDKKEWDQQLPIDFGEGEDVTTEVYIL FT DHKAERRLCRKFDFRILPLLALLYLFNALDKSNVSNAKTNGMDKDLGFVGDQYNIMISI FT FYIPFVLCAFPFSYLYKRFGAARILPFFMLSFGAMSLCQAAVKNFGGMMAVRWFLGMAE FT SAVLPGVVYYLTTFYRRTELARRLAIFYAAANVSSAFGGLLAYGVFHIKGGKLQGWQYL FT FLIEGGVTFLCAIVIFLVLPVSVETANFLTDEEKTLAKMRIENDSSSAISEKLSFKQSL FT TVFKHPIAILWLLEEMALGVPLNSINNWLPQIVAAMGFSSVNTNLMTVAPAISGAIWLL FT VFAFISDFLKNRGIVLIAAISTTMIGFIVYGSIDIMNHIGVSYFACFLMTAGAAASSVL FT TSTWYNNNTPNESRRAVFTSVGVPLANVMGLVSANIFRPQDAPKYVPALGITAGFGGLG FT ILLVASISVYMFFDNRRRDNAQGVKKTFADVSTKDLGEGPANPNFRWFL" FT misc_feature 11127..12374 FT /note="Pfam match to entry PF00083 sugar_tr, Sugar (and FT other) transporter," FT CDS join(complement(15300..15420),complement(14072..15198), FT complement(13897..14018),complement(13553..13851), FT complement(12865..13497),complement(12770..12813)) FT /db_xref="SPTREMBL:Q9US36" FT /label=SPAC1039.05c FT /note="SPAC1039.05c, len:781, FT SIMILARITY:Schizosaccharomyces pombe, AAF13704, c2h2 zinc FT finger protein zas1a., (845 aa), fasta scores: opt: 1228, FT E():0, (32.7% identity in 842 aa)" FT /gene="SPAC1039.05c" FT /product="C2H2 zinc finger protein" FT /protein_id="CAB63541.1" FT /translation="MTKAKKSRAYQEGDIRYKCDFQGCTKSFTRKEHARRHFRSHTNSK FT AFICPHCSSSFTRSDVLNRHVNQKHVKQNDAGSQTHPKHDKTLISSSDQELPFPSYVEA FT DVQDAAYTDLKSHIDQPILPDQPIISDNFNEGLQSAIAQTGNNYMFTTSRRNNSISGSI FT TIPESDQQINLQNKFLSTPSIKNNANKSLSPQDSISIFGTSPFNAYQQNTDNFVCWLFD FT NMEKDAPTESVSNFTDGINAKQLNLMPVLDSPTIDFLSSHFRVDDKLVAKDLLSLSAYS FT SLIQVMNNNYQLSEEALQYITRSRVNLWIAHYWKDFHPRWPFLHRGTLKVDEAPVELLL FT AMITMGMHFVGDAFAYSIAVSIHSTLRFSIYTHPDFKPPASLWVYQALLIAEIFEKMTS FT TVEQHNLSQIFHGVTIESMQNGLSSKDTVTEKIPKNMTGTNIAQHKWHQWVDREASKRI FT AFFSFVLDSQHVILFGYRPLIDITSVGLPLLCDEALWNADSYEAWTSLLNENDPPHFFP FT VLKMFLTNEHLPPKLSPWNMMIVLHGLTTIGWILSRENLGIVENIMQNNGTNLKNWRIL FT LKASYKFWLRTYRVFFLNNGTLPLNHPYVRGCLATYELAHISLHTNIVALQTYAKSIVS FT TSRRLYASTSRYVSAWLASDDSEVSIKHAVDMVEAFLGGDMEYDVQNETGLHRPWCLYV FT STLILWAYGYVSDGRCEMLEPGNNDCKSQLNAYLMQMRTGLSEKAKDHVYVRSKTLPLL FT KCVIDVLCPARWGLLVDGVRILSKLVQL" FT misc_feature complement(12814..12826) FT /note="ctaacagttttag, splice branch and acceptor" FT misc_feature complement(12859..12864) FT /note="gtaagt, splice donor sequence" FT misc_feature complement(13498..13513) FT /note="ctaactggttttaaag, splice branch and acceptor" FT misc_feature complement(13547..13552) FT /note="gtacga, splice donor sequence" FT misc_feature complement(13852..13864) FT /note="ttaacactattag, splice branch and acceptor" FT misc_feature complement(13891..13896) FT /note="gtaatt, splice donor sequence" FT misc_feature complement(14019..14028) FT /note="ctaattctag, splice branch and acceptor" FT misc_feature complement(14066..14071) FT /note="gttcgt, splice donor sequence" FT misc_feature complement(15199..15208) FT /note="ctaattatag, splice branch and acceptor" FT misc_feature complement(15211..15282) FT /note="Pfam match to entry PF00096 zf-C2H2, Zinc finger, FT C2H2 type," FT misc_feature complement(15294..15299) FT /note="gtatgt, splice donor sequence" FT misc_feature complement(15298..15372) FT /note="Pfam match to entry PF00096 zf-C2H2, Zinc finger, FT C2H2 type," FT CDS 16592..17839 FT /db_xref="SPTREMBL:Q9US35" FT /label=SPAC1039.06 FT /note="SPAC1039.06, len:415, SIMILARITY: LOW to FT Saccharomyces cerevisiae, YGU6_YEAST, hypothetical 18.1 kd FT protein in mds3-gcn1 intergenic region., (165 aa), fasta FT scores: opt: 346, E():6.5e-15, (42.4% identity in 165 aa)" FT /gene="SPAC1039.06" FT /product="hypothetical protein" FT /protein_id="CAB63542.1" FT /translation="MASNVDKFSSRFYLNVNKEELKKEYVGKTIQQVPTPGFVIDEAIF FT EKNCNRMLDRASDIGVTFRAHVKTHKTIEGTLLQLGDGRTKAVVVSTLMEGFSLIPLIL FT EGKIDDLLYGLPVAKSRLPELYELSKIVPHLRLMIDNPKQLDILREFTSTLPDDAKPWS FT IFVKIDMGTHRAGVTNDSQVVKDLISTILSDKSLFDLFGFYCHAGHSYASRSIDAASEF FT LCAEIDAANTAAKFATSIDPSLKLTLSVGATPTAHSVSPKVKELLPTLSGKLEVHAGNY FT PMNDVQQMITKCISQADVADYVFAEVISNYPGRNGEPGEVLVNAGVIAMSRETSPEGDF FT GIVITPGFESFYVDRLSQEHGILKSKDPKATLPDASQVLCIIPNHSCITAAAFPWYYIT FT KGSDVITDIWVPWKGW" FT CDS complement(18468..19814) FT /db_xref="GOA:Q9US34" FT /db_xref="SPTREMBL:Q9US34" FT /label=SPAC1039.07c FT /note="SPAC1039.07c, len:448, SIMILARITY:Burkholderia FT cepacia, DGDA_BURCE, 2,2-dialkylglycine decarboxylase, (432 FT aa), fasta scores: opt: 1588, E():0, (56.6% identity in 429 FT aa)" FT /gene="SPAC1039.07c" FT /product="putative aminotransferase class-III FT pyridoxal-phosphate" FT /protein_id="CAB63543.1" FT /translation="MSSHVSNNSILDPVTFWNQANKSLIRYGGDFAPKIIVRAKGCCVY FT DEQDNAILDFTSGQMSAILGHSHPDITACIEKNLPKLVHLFSGFLSPPVVQLATELSDL FT LPDGLDKTLFLSTGGEANEAALRMAKVYTNKYECVAFSSSWHGVTGGAASLTFAAARRG FT YGPALPGSYTIPEPNPKLSPFRDAKGNYDWQKELDYSFYMLDKQSTGSLACMIVETILS FT TGGIIELPQGYLKALKKKCEERGMLLIIDEAQTGIGRTGSMFSFEHHGIVPDILTLSKS FT LGAGTALAAVITSEEIEKVCYDNGFVFYTTHASDPLPAAIGSTVLKVVKRDNLVEKAKI FT SGELLRSDLLRLKDKHPLIVDVRGLGLLQGIEIASCTDPSKPSDFLGTVIGDKCLELGM FT NCNIVHLRGIGGVFRIAPPLTVTDEEIHKAIEIFDSALTFTAKEFSGSY" FT misc_feature complement(18558..19694) FT /note="Pfam match to entry PF00202 aminotran_3, FT Aminotransferases class-III pyridoxal-phosphate," FT CDS 20273..21085 FT /db_xref="GOA:Q9US33" FT /db_xref="SPTREMBL:Q9US33" FT /label=SPAC1039.08 FT /note="SPAC1039.08, len:270, SIMILARITY:Arabidopsis FT thaliana, AAD32947, serine acetyltransferase, (317 aa), FT fasta scores: opt: 637, E():0, (43.4% identity in 235 aa)" FT /gene="SPAC1039.08" FT /product="probable serine acetyltransferase" FT /protein_id="CAB63544.1" FT /translation="MTVQTAERTITLVQAIWPKLRKEAEKQCEVNPWLAKDLARKILSK FT KTLRESLSCVLALPLDHVTGSSESMENWFYSILGLNDEKIIRSAMIDLDRLYTTNPACP FT DLISAFLSFRGFHALQLYRIAHGLWSEGDKTSAVLVQNWTAVAYGVDIHPAASIGDGLF FT LDHALGIVIGETAIVEDGVSIWHNVTLGSTFKDSGARHPVIRKNAMLCTGATVLGRVEV FT GENAVVAAGALVTKDVAPNRLALGSPARDVGPVPQYFGALTNPNCTNK" FT misc_feature 20786..20848 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats)," FT misc_feature 20882..20986 FT /note="Pfam match to entry PF00132 hexapep, Bacterial FT transferase hexapeptide (four repeats)," FT CDS 22803..24545 FT /db_xref="GOA:P40901" FT /db_xref="SWISS-PROT:P40901" FT /label=isp5 FT /note="SPAC1039.09, len:580" FT /gene="isp5" FT /gene="SPAC1039.09" FT /product="sexual differentiation process putative FT amino-acid permease isp5" FT /protein_id="CAB63545.1" FT /translation="MNNYGVSSIGTSLTPSPTGSIDEYTSKEVKHPEDVKVDASYEKEE FT VGYGELEVVPERGNLFQRWYRSFLPPEDGKPQKLKRTLTARHIQMIGIGGAIGTGVWVG FT SKNTLREGGAASVLICYSLVGSMVLMTVYSLGELAVAFPINGSFHTYGTRFIHPSWGFT FT LGWNYLASFLATYPLELITASICLQFWININSGIWITVFIALLCFVNMFGVRGYGEVEF FT FVSSLKVMAMVGFIICGIVIDCGGVRTDHRGYIGATIFRKNAFIHGFHGFCSVFSTAAF FT SYAGTEYIGIAASETKNPAKAFPKAVKQVFIRVSLFYILALFVVSLLISGRDERLTTLS FT ATAASPFILALMDAKIRGLPHVLNAVILISVLTAANGITYTGSRTLHSMAEQGHAPKWF FT KYVDREGRPLLAMAFVLCFGALGYICESAQSDTVFDWLLSISNLATLFVWLSINVSYII FT YRLAFKKQGKSYDEVGYHSPFGIYGACYGAFIIILVFITEFYVSIFPIGASPDAGAFFQ FT SYLCFPVVVIVFIAHALITRQKFRKLSEIDLDTGFSKYDRLEESDKGPMTAKSLAKSVL FT SFCV" FT misc_feature 23037..24413 FT /note="Pfam match to entry PF00324 aa_permeases, Amino acid FT permease," FT misc_feature 26685..27893 FT /note="nominal overlap with cosmid SPAC922 S. pombe FT chromosome 1" FT CDS join(26939..27252,27309..27375) FT /db_xref="SPTREMBL:Q9UR06" FT /label=SPAC1039.10 FT /note="SPAC1039.10, len:126, SIMILARITY:Schizosaccharomyces FT pombe, YB94_SCHPO, hypothetical 17.5 kd protein in FT chromosome ii., (162 aa), fasta scores: opt: 438, FT E():1.8e-24, (62.5% identity in 104 aa)" FT /gene="SPAC1039.10" FT /product="putative translation initiation inhibitor" FT /protein_id="CAB63546.1" FT /translation="MSKVPINSSKLSCGGPYNQAVKSGGLIFCSGQAAVKDGNFVPGTI FT QEQTRLTIENLAEVLRVAGSSLEKLVKVNIFLTDIDDFAAMNEVYKEMLPDPMPARTTV FT AAGKIPLSSKGGKIEIECIAAE" FT misc_feature join(26981..27252,27309..27372) FT /note="Match to UPF0076 , Score 127.08" FT misc_feature 27253..27258 FT /note="gtaagt, splice donor sequence" FT misc_feature 27297..27308 FT /note="ctaattatctag, splice branch and acceptor" FT CDS complement(27586..27893) FT /codon_start=3 FT /db_xref="SPTREMBL:Q9US31" FT /label=SPAC1039.11c FT /note="SPAC1039.11c, len:101, FT SIMILARITY:Schizosaccharomyces pombe, YAJ1_SCHPO, putative FT family 31 glucosidase c30d11.01c precursor, (993 aa), fasta FT scores: opt: 250, E():1.4e-11, (40.8% identity in 98 aa)" FT /partial FT /gene="SPAC1039.11c" FT /product="putative family 31 glucosidase" FT /protein_id="CAB63547.1" FT /translation="SLYVDDGVSIQQESTLFVKFVANGDSLSIESYGDLQVHEPLSKIT FT IIGLPCAPIGVYFEGVQVESFSYLEDTKELVLTNLEAFTSTGAFSNNWTISWNLPV" FT misc_feature complement(27718..27891) FT /note="Pfam match to entry PF01055 Glyco_hydro_31, Glycosyl FT hydrolases family 31," XX SQ Sequence 27893 BP; 8487 A; 5097 C; 5010 G; 9299 T; 0 other; tcgatatgcc ataatgcacg ttctttttat ttttatcgta ttcatgatcg ctatgaaatt 60 gttgttcttt taaccaaaaa agagaagcta gaattattat aatacaactt gataaaacct 120 tttttcatct gtccaaaaaa atttttttac gattataatg tttacccatt tgtacatggg 180 ggcatatatc ttaagcaacc ttctcactcc atacccctag attaaactgt tggaagtaac 240 ggtttaagat agcattacta tattatcgcc gttacagtct tttgtttata ccatttttca 300 cttattttag tattgtacgt ctcatctacg gatattcgca gatgtacatc atattagcca 360 ctgtaaggta cttcgttata tatggatact gtgatgtcca gtagtatttt ttaaaatttt 420 tctcggtaca aaataagtgt aaatagtttt tataatacta attatacatc agggtcctat 480 ataagcaaaa caaaaccact ttgctaacat gttttataaa ggtcttaaga ctctctttct 540 taagcaattt ctttctctat cataaatttc gttctccatt ggctgttagc caaaaatagg 600 atggaaatct ccacgtcaat atctctttcg tactctatca tattcactac actatgcttg 660 accttgcaag tcacaagatg aacaataggc aagtcgatat taatctagat gtctgggtat 720 cagtgtaaat taagtgtttt tgtctatcta atctaaggag gaaaaagcac agtaaattaa 780 aaaatttctt gcctgctttc ctcggggaga cattttttta tgttcgtccc cactcttctc 840 gatgcttaaa tggagggtgg tagccacgtt ttctggatcg gtttttgttg gttcacgttg 900 actcacctta ttttggctca cttgggtaat gtgtttatag gaaaatcagt aatttgaaat 960 tgttgctttt ttatattaaa catatcaaaa agttttacaa gattgtatag tcttcaaatt 1020 atttttttct ctcttcatat tatatttagc tagtttgttc tttggctctg aactattgtt 1080 tcaacaggtt ttttccataa gttcctcttt tctattctgt ttttgaaata ttcttaatca 1140 tattacatgt atgtgagtgt gcagcaaaca gttctatata tatcttttat atatatatag 1200 acatatggat gttataaaaa aaatgaataa aatagagcga tcgctactat gactaacttt 1260 ttttctttaa acatcttatg tcgatcctaa agctttttta tattataatt gtttataagc 1320 tgccattgtt gagaaaaatc actaatcttt agtcttgttt tagttttctt aaaaatgtcg 1380 tctattatgg aaaaaacgga tgtttcctca tcaaagcata gctttacgtt tgagccttcc 1440 tctgacgaag ttggtaaagc tgctgaaatt gttgataccc atgaaaattt ttacgatgat 1500 caaggtgaca ttgataatcc tgaagaattg gctgagttgg gttataaaca agagtttcgt 1560 cgccagcttt ctctatttgg cattttctcc atctctttct cggttctcgg tatgcttccc 1620 tctgtcgctt ctactttggt ttttggtctt tggtacgttg gttatcctgg tttattatgg 1680 gcttggttaa ttgcaatgtt tttccttatc tgcgtttcca tgagtatggc agagatctgt 1740 tcagcaatgc ctacttccgg tgggttgtat tatgctgccg ctgttttcgc tcccaaagga 1800 tggggcccct tagcctcttg gatcactgga tggtctaatt atattggtaa tattattgga 1860 cagccatctg ttaattcctc tgctgctagt atgattctag gtgctgttac tgtcaatcgt 1920 cccgactttg tcattcagcg ttggcaatgg ttccttttgg ctgtagccat ccagtgcttt 1980 aattgtgttc tggcctgctt gccaactaga atcatttctc gtattaatgg tgtagcaacc 2040 tacctaaaca ctgcattcct tttcatcgca ggtattacga tcttagctta tggcggtaaa 2100 aatcataact ttgtgaaggg aacaaagatt tggggagatt atattaacac aacccaatgg 2160 cctaccggtt ttgctatcct tctttccttc aacagtccta tctggaccat gtctggttac 2220 gatgccccct ttcatcttag tgaagaatgt tccaatgcaa gtgttaatgc tccaaaagcc 2280 attgtaatga ctgcagttat tggaggtgta gttggatgga ttatgcaaat tatcgtcgcc 2340 tataccttaa ctgatattga ctcggttatg aacacatctg gatctatgtg gacggcttat 2400 cttgtacaag caatgcctcc taaggctgcc ttgggtatat tgagtcttac gattatttct 2460 gccatcatca tgggtcaaag tgcacttatc gcttcatctc gtatcgccta ttcctatgcc 2520 agagacggta ttcttccctt ttcaggttgg atcggcacgg tcaacccata cactcaaact 2580 cctgtaaatg ccgtaatatg taactgcatc attagtatcc ttattttgtt ccttacgttt 2640 gctggtacag tcaccttaga tgctgtattt tctgtcggtg ctgttgctgc ttttattgcc 2700 ttcactgttc caatcgctat tcgtgtcttc tttaccaaag atgctgattt ccgtagaggt 2760 ccttggaatt tggggaaatt ttcaagaccc attggtcttt tggcagtctc gtttgttgct 2820 ttgatgattc ctattttatg ctttccatct gttaaaaatc caaccgctca agaaatgaat 2880 tggacctgtc tagtgtatgg gggtcctatg ctcttcaccc ttgtatggta tgccatttca 2940 gcacgaaaat ggttcaaagg tccaaaagcc agtgcccatt ataaaagacc aggtgaagaa 3000 tcgtcggata tcgttgaagg cgtacaagct gacattccat cctcatctga ccagcttaag 3060 attaaaggag atctttaatt tattgttatt cttttcaatt atttgcctaa ttttaggaaa 3120 aattctttct taaaatataa ggtgatgttt gtacagtact atcgtatcat ctgatttttc 3180 gaatttttta tatttatgct gttaatacat aagcgcatct ttacttttat ttaaaatccc 3240 ttcctcgttt gaagcttgct gtctctaagt tatggtattg ccgctgatac ccattgcaat 3300 tatttgttac gtttatcaat gcttcaaata aacaatagcc cattcaacat gaatgatgtt 3360 tagataatca tttttaggca taagtctcaa cttgatggtg gaataatatc aacacataat 3420 cccaagtctt tgaaagccct catttctttt tgtgatacct attggaatct caggagcatt 3480 ttaaaaatct ttcttttaag gacagaacca ttttctataa tagtagctaa tttttgtttt 3540 cgtaatttta atgatatgac cattattttt ctaagtaaac atggggccat agtccattgg 3600 tatcataatc gtatatgtga aatccaaatc attataagtg atacagaaat tttaaactat 3660 gattattctt gaatttgcga gtcaataatc ggcaatgttt accacgtaag tcaaaagcga 3720 cgtttgctta gttttttcga gtgcaatgga ttggacactt ttcgaatcgt cgtaatttgt 3780 cttagtcaaa gttttatatt tgacgattga tgtcgatttt tgtaaggtgc atatctacca 3840 tgatgcacaa tggtatttta tgcagcgtat gatgaattat tgttgaagtt ttgtcattct 3900 cgtttacaat atgttctttt gaataaagtt gatgatcaaa ttattcaatt tgttaaattt 3960 gttacaagtt caataattca ctcagcttat atttaaacga acggatgcta acttaaattt 4020 tactaacact ttaacgatta taattttttt tctttattta tttatttatt ttttttttaa 4080 ttttaaattc aatggatgaa agcaatcatt aattccagtg ctagtagtag agcaataaat 4140 tgatttatat ctttatggat taaaaatact attttactct taatcttgac tcactgtttc 4200 acagccataa agctttcccc ccttgattaa ccgagccaaa ttcctttcat cataacggat 4260 ttcaaagatg atgccactgt taaaacatat atattatgta tgtatgaaga taaatatccc 4320 actgtttaaa cttgcggata aaagaactcg aacgtcggtt gttaactgaa caactttaga 4380 aaataattta aagttggtat tggaatatga agagtcgttc tcttgacgat aaaatgaaat 4440 attataattt attcaattat ttatctttaa ctaattcaat tatttgctca tatttgtgaa 4500 cgtttggtga aatagaatat ttgttcctcg tcccatattt attttttatt attgcattca 4560 attaattaac tataacaaaa ctttgttgag cttatatttc ttacaaagtt tgtttgtttg 4620 aataaatatt attattatta ttgttttctt gatttaaaaa atatatttta taaatgaatg 4680 aagcatagac tattaaaaaa atttacatat ttcataaaaa tcggttctta atctaattac 4740 ttcaaaatac tgataagcta cgaggttctg gaatgagtaa agatgctctc tacctctatc 4800 gatttctaaa ctatcaagtc tgtcaaaatt tttaactaag aaataattcg ttgtttatgt 4860 tctgaactgc agctgtcttt gatatagcga ttatcgcttg ttcaaaaaac gaaaggatgt 4920 ttcgttttcg tttacccaac acccggggta gaaattctcg gccccacatt tacccccaaa 4980 ttagtaaggg aatttgaaga ctttcttcag ggacaaatat atgatagaaa gactaaatgt 5040 gttatttttg gaagtcttcg gatatatctg ctactctatt tttatttatc taagaaaatt 5100 tcacgataat tccaccaaaa ctcgatagca gtattcattt aatcgtgaat gtgctgcaca 5160 tttcaaaatg tcaagcttta tagatcaact ttgtcgaacg attctacgta ataattagcg 5220 aaaagggcat aaatggcata atgataaagt aaaaatttcc taattatatg ccgtctacta 5280 ccaacagcct cggctctccc ttcggtacac taaaatttga gcctttccct taacgatact 5340 tcccaaatag taaagatatg acttaggagg tagtgctcac attcaatagc agattgccaa 5400 caaataacta atctatgact ttttcaataa agaacgaata aaaaaaagct aatagaatat 5460 ctttcgtttt ttgttataca atttcaaatt cctcctaaat tctagacatg agaacactag 5520 caaaatagga ccgaaattct ccgacctaat cttgattggg ctccctctaa acacggtgaa 5580 ttacaaaatc aaaaggtcac attcctagga atgaccgagg gaaataatgc ggtgtcattg 5640 agaggacgaa ttttttaata cataaattgc aattgcctgc ccaatatgaa gcaaactttt 5700 taatttattt ctttttgtta caaagtttga tcatcttcaa aatgaagtta tcatctttac 5760 cttctggatt gggcctagcg tctttgcttg gtcttatcag ttctgctact gcttattcgg 5820 ccaccgattt aactacgatg tatgattgga accaaataat caaaccttta gaatggggac 5880 aattgaattt cattcatact acggatactc acggttggct tggtggtcat cttagagatg 5940 ctcgttataa agccgacttt ggtgaattca aatcgtttgc tttgcgcatg aaggaattag 6000 ctgattttaa aggtgtagac ttgttgatgg ttgacaccgg tgatttgcac gacggaaacg 6060 gcctttctga tgcttctgat cctcagggta tctacacaaa caacattttc acctatcttc 6120 cctacgatat tcttacaatt ggtaatcacg aattgtacca agccgccatt tctaataaca 6180 cgcatgagta ttttgtgcct cattggaatg gtacgtatct cgcttctaac gttcaaattt 6240 acaactcatc aaatgaattg gagcaatttg gtggtgaatc cacttacttt attacaaaac 6300 atggtgttcg aacccttgct atgggttttc tcttcaactt cagtagtaat gctaataaca 6360 ctgtcgttac acccgttgaa acagccatca aatctgaatg gtaccaacaa caaatcaaca 6420 gaaccgacgt cgaccttttc ttattgattg gtcatatccc cgttcgtgat tatgatgagt 6480 ggaaatcact acatgcctct attagaaaag tacatcccaa tactcccatt caaatccttg 6540 gtggtcattc tcacattcgt gattttgctg tttacgacga ggcttctgta tctcttgagg 6600 gtggaagata ttgtgaaact gtaggctggc tttcaattga cggtctttca gcatccaatg 6660 caacccgcca atatgttggt cgtcccgtca ccaatgagac tcgtcaatca tatcccaatc 6720 ttcctaagcc tgctacgcct ttgtattata cacgtcgcta cattgatttc aaccgtcaaa 6780 acttccgctt ccatactcaa cagtcagagg actccttcga tactccagaa ggtgttgaac 6840 tatcgaaggt tattaaacag taccgtgacg atcttaatct ttcatatgtc tttggatgca 6900 tccctaaaaa ttattatatg actgaagtct ctcctcaagc cgaggacagc atcttcaaac 6960 ttatggtaga tcatattttg ccagaggttt tggtcaatga aaaccgttca tctgtgcctc 7020 atattataat tagcaacgga ggtggtgttc gtggttctat gtatgaagga acgtttggac 7080 ccgacgaaat gttccaactt aacccattcc ttaccaatta ttataattac attccagacg 7140 ttccttacaa atatgccaag aagctttact ctatcttgaa tggcggttcc actcttcgca 7200 acgttaacga ttatcttgct gctctcaatc ctggttacgt tactagcgac gactttggag 7260 aagatggcga tgacaccgtc catacctatg tttccacata cgcagtacct aacgttcttc 7320 aagctcaagt cggctttaac actacttcag ctccagaaac cgttgatgtt gttttcctca 7380 actatttcca gaccaaagta ttgaaggccc ttaatacaat ggttaacgaa actatttata 7440 ctttatcaaa cgtgacacaa tactgggttc gtgaagacgg caaagacagc tctccttata 7500 tgtttgccca gtacgttcaa caagaatgga gtgattactg tgattaaaca gggaatcgtc 7560 aactcaatta aactaccgat ctttttcctt agaagttgta cataatctca gatttgtttt 7620 tactatttaa acctagttta ttaatattat aaatataatc aaaccgattt tttaagttta 7680 tcgagtcgaa gaagagagtt ctagcagtac aagatgtatc atgaagaaat tggtagacag 7740 tgaaattgaa aaataaagta aaaaaaaaat cagtaatacg aatatccgaa aataagttag 7800 ttaacggttt ttatgtcagc gactgcatgc tacgtattta tcccgtatgt aaacattgga 7860 attagcaatt aagacatgta catagatatg atcgcaataa aaccattatt ccttcagaca 7920 ttccttgatt tccagattaa gttaatatta acacaaataa aattaagcag aacctcgttc 7980 ttatggagac ttaaactata ttagtgatat gttattatat taattagcac cttgttacgg 8040 gaatatttat aaagctgaaa ttcatactgg tacaagtaga aacacaccgc agtataacga 8100 atcattataa ctgattacaa agtacttagt ttaacaatag tgtatttaat taatctcaat 8160 attgctcaag ctgacttctg aattttcgag ttcatagtag acttcactca ttgttcagta 8220 attttgagct tggtaaattt ctaaacctta acatttgttt atcggttgaa aaattcacat 8280 ttttttagat tcattttatt tcaaacccca tgaactagta aatccacaat tcgatacgag 8340 aatcagtata ccacctgacg aagtctctgt gataaaacca aaatttctaa ggcttagata 8400 tcaatgcctt cttcataatc tcaaagtgga taaaccccaa cactttgata tcaaaatcat 8460 tcattatatt taatcattta attctggtgg agtcttaaga atgagatatc tgttttcaag 8520 atacccccac cacatgggga accatttcat gcaatccaaa actgattgtt aggggttatc 8580 tactatggtg atggggcaac ttcggaagat tggttttcaa aacggaatat gttatttaca 8640 agatttatat aagacccttt ctgctctcca tgaagcagcg gtttataaga cacaaacatt 8700 cttgacttga gtccaagtat ttttttctat tacttacaac tttctttatc aatatgagcc 8760 aaactacaac tgagaccatc attccactag acagttccgt gaaggacaag ttggatcctg 8820 agtacgtgaa cttctacaac aaatatgtgt gcagcaatct tccaatcgtt aaaacacaca 8880 cttatcctgt tgactttttg agaaataatg gaaatgttat gcccgggcaa tccgaattac 8940 ttcctgttga atctactgaa gatataacca tcccccgtaa acacaccaag gctcccagcg 9000 gtgtcccctc ccgtattttt agacctcatg gaactgcacc tgaaggtggg tggccttgtt 9060 tcctttggtt ccacggtggt ggctgggttc taggaaacat taacactgaa aactccttcg 9120 ctactcatat gtgcgagcag gcaaagtgtg tggtcgttaa tgttgattat cgtttagctc 9180 cggaggatcc tttccctgct tgcatcgatg acggatggga agctttactg tactgttatg 9240 agaacgctga cactcttggt atcaatccta acaaaattgc tgttggcggt tcctctgctg 9300 gtggaaacat tgcagcagtc ctctctcata aggttgcagc atctcctgct aactttccac 9360 ctctcgttct tcaactttta gttgtccctg tttgcgataa cacagctaat gccaaaactc 9420 acaaatcatg ggaattgttt gaaaacactc ctcaattacc ggctgctaaa atgatgtggt 9480 atcgtagaca ttatctccct aacgagaaag attggagcaa tcccgaagct agcccattct 9540 tttatcccga ttctagtttc aaaaacgtat gccccgcttt aatttgtgct gcaggttgtg 9600 atgttttaag ctctgaggca attgcttata atgaaaaact cacaaaagct ggtgttgagt 9660 ccacgattaa aatttatgaa ggttgccctc atcctgtcat ggcaatggat gctgttcttg 9720 aaaaaggtcg aattctcaac aaggatgcta ctaacgcttt gttagcagca tttgcttaag 9780 gtagtttgta gttaattatt ttttagaagt ctttacatat actgtcattt taaattccac 9840 atgctattcc gtaattaaat aacaatataa tccaattgaa cttattattc tcatgctcta 9900 ctagaaccta gtttatttgt gtaacaccct agcaagaagc gaattattaa agaaagattt 9960 catatcttaa atgccaactt caaagctata attatctgta cttgctatga ttatctgtac 10020 tttatttgta cttatgaaat cagtaattca atggaataac gatgaatatg taaattttag 10080 ttttaaaatc tgtttttgca ctaccgaagg agaggattta ctcattggtt taggatactt 10140 catcctatct attgatagtc aagcaattca tattgaaaga taacatgctc acaatcgtaa 10200 acaatttaag aaaaaactct tgcgctacga acacgatcag atatgcattt aatcatggat 10260 tcaacgatgc attctctgac ttttgcgcca gatagcgccc ccatctcatt ttatctatta 10320 tgattataca ggctttaaca aagcttgtat atcttgtcgc ctaattatac aaagagtgac 10380 aagctttgag atgtttaggt atccaatttt taaaaaacaa actaatggag ttatgctttt 10440 gcgatcttta tttgccaaca attattttct tttttagaat taatgtaaaa tgtatataat 10500 tttaagaaaa ttacagcaat caaagtgtta gttttcagaa catactaatt cgcttaaagt 10560 cagtcatcct tatcatttca aaattaaaaa tgccagtaat gcatcttaaa aagttaagat 10620 tatatctttc actcaccacc acacacaaca tagatataat aatgagggaa aagatatctt 10680 gctggacatg aaacccttga gctgtttgta tcactttaca gagcatcccc aaagtattga 10740 acggtggggg cttttgttaa agattagagg aattagttga gaaaacatta tatatattgt 10800 tgctaaatgt tgtatttggc atcattaatc aaatagaaca tctttgatat acctcacaaa 10860 caagtgattt aaagttattt aaaaataaaa gtttgaagga aacagaactt ttaatattct 10920 gcaacatgga gaaatctata tcatccattt caaaggcgtc aatgaactca gatgaaaagt 10980 tagacaagaa ggaatgggat cagcagctgc ctattgattt tggagaaggt gaggatgtga 11040 cgactgaagt ttatatactt gatcacaagg ccgaacgaag gttatgtagg aagtttgatt 11100 tcaggattct ccctcttttg gcccttctat atctgtttaa cgcacttgat aaatcgaatg 11160 tgtctaacgc aaagactaat ggtatggata aggacttggg atttgtaggt gaccaataca 11220 atattatgat ttccatattt tacatacctt ttgtcctttg tgcttttcct ttttcgtact 11280 tatacaaacg cttcggagcc gcgagaatat tacctttctt tatgctttcg tttggggcca 11340 tgtcactttg ccaagcagct gtcaaaaatt ttggtggaat gatggcagtc agatggtttc 11400 tgggaatggc agagtcagca gttttaccag gcgtagttta ctatcttact accttttata 11460 ggcgtactga attagctaga cgactggcca tcttttatgc agctgccaac gtttcttccg 11520 catttggcgg tttactagct tacggtgttt tccatatcaa gggtggaaag cttcagggat 11580 ggcaatattt gtttttaatt gaaggaggtg ttaccttctt gtgtgcaata gtgattttcc 11640 ttgttcttcc tgtaagcgtt gagacagcta attttttgac tgatgaagag aaaacacttg 11700 caaaaatgag aatcgaaaat gattcatctt ctgcaatttc cgaaaaatta agcttcaagc 11760 aatctttaac tgtgttcaag catccgattg ctatcctttg gctattagaa gaaatggcac 11820 tgggagttcc tttgaacagt attaataatt ggcttcctca aattgtagca gctatgggat 11880 tttcttcggt caacaccaat ttaatgacgg ttgctccagc catctctggt gctatatggc 11940 ttctcgtgtt cgcatttatc tcagatttcc ttaagaatcg tggtatagtt ttaattgctg 12000 caatctccac aactatgatt ggatttattg tatatggttc aattgatatt atgaatcata 12060 ttggtgtctc ttattttgct tgctttttaa tgactgcagg ggcagctgct tcatctgttt 12120 taacgtcgac ttggtacaat aataatacac cgaacgaaag tcgtcgagca gtttttacct 12180 ccgtcggtgt cccactagcc aatgtaatgg gtctcgtgtc agccaatata tttcgtcctc 12240 aagacgcacc taaatatgtt cctgcgcttg ggattaccgc aggctttggc ggtttaggta 12300 ttctattagt cgcttcaatc agtgtgtata tgttttttga caatcgacgc cgcgacaatg 12360 cacagggtgt taaaaaaacc tttgctgatg tcagcaccaa ggatttaggt gaaggacctg 12420 caaatccaaa ttttagatgg tttctctaaa cgacatgcat ttcttttgtt tttttgttat 12480 agcgcatttt caacgatttt gttttgtttt tttacctgtt ttctttgttt ggatttattt 12540 tgaaattaag gaccatgtct ctagtaaact agcgcaacag cggttttttt tttatgtccc 12600 atcaccagcg aatatacttt aataatataa ctagcttaaa taagttattt ctaatgatat 12660 tctgaacata ttaatcacaa atattcaaaa tgcgtaaatt aaaactatgg attagaaata 12720 atgtaaaaaa tgctataata caagaaatcg ttcgttatac atcctcaagc taaagctgta 12780 ctaatttaga caaaatgcga acaccatcta ccactaaaac tgttagtatt tgatgaacaa 12840 tacaactacg aaagatcgac ttacacaaac cccatctagc tgggcacagc acatcaatga 12900 cgcattttaa taatggcaga gttttacttc gaacgtagac atgatcttta gctttctcac 12960 tgagacctgt tctcatttgc ataaggtagg cattaagttg agacttgcag tcgttatttc 13020 ccggttcaag catctcgcac cttccatccg agacataccc ataagcccaa aggattaagg 13080 tcgaaacata taagcaccag ggtctatgaa gacctgtttc attctgaaca tcatattcca 13140 tatcacctcc taaaaaagct tcaaccatat ccacggcgtg cttaatagat acttcagaat 13200 catcagaagc taaccaagca gaaacatagc gcgatgtact cgcatagagt cttctagaag 13260 tggagactat tgattttgca taggtttgta aagcaactat gttagtatgc agcgaaatat 13320 gagccaattc atatgtagcc aaacagcctc gcacgtaagg atgattgagt ggtaaagtac 13380 cattatttag aaagaataca cggtaggtac gaagccaaaa cttgtaagat gctttaagta 13440 aaatcctcca gtttttcaag ttggttccat tgttttgcat gatattttct acaatacctt 13500 taaaaccagt tagttattga aatcgttaaa ttagaaattg caatgctcgt acccaaattc 13560 tctctactta atatccaacc aatggtagtt aatccgtgca acacaatcat catattccaa 13620 ggacttaatt taggaggaag atgctcgttt gttaagaaca ttttcaagac gggaaagaaa 13680 tggggtggat cgttttcatt taagagagat gtccatgctt catagctatc ggcgttccag 13740 agagcttcat cacataatag aggtaagcca acgctagtga tatcaattaa cggtctatat 13800 ccaaataaaa taacatgctg agagtctaat acaaatgaaa aaaatgcgat tctaatagtg 13860 ttaataacca tcacttaaag tcaccagata aattaccttt tcgaggcttc tcgatcaacc 13920 cactgatgcc atttgtgttg tgcaatattc gttcctgtca tgttttttgg aattttctcg 13980 gtgacggtat cttttgaaga cagcccattt tgcatagact agaattagtt agagaaagta 14040 ttatttaata taaaacgcta atgtaacgaa cctcaatggt cacaccatga aaaatttgag 14100 agaggttgtg ttgttccaca gtactggtca ttttttcaaa aatttcagct attaagagag 14160 cctgataaac ccaaagagag gcaggaggct tgaaatctgg atgcgtatag atggaaaatc 14220 ttaaagttga atgaatggaa acagcaatgc tatatgcgaa tgcatcacca acgaaatgca 14280 tacccattgt aatcattgcc aataaaagtt ctacaggtgc ttcgtcaact ttgagtgttc 14340 ctcgatgcag gaaaggccac cgggggtgaa aatccttcca ataatgagca atccataagt 14400 tcaccctact gcgagttata tattgcaacg cctcttcaga aagttgataa ttattattca 14460 ttacttgtat taaagatgaa tatgcggaaa gtgatagtag gtctttagca actagtttgt 14520 cgtcaactct aaaatgcgaa ctaagaaaat caatggtcgg tgaatctaaa actggcatta 14580 aattcaattg ctttgcattg ataccatcgg tgaaatttga aactgattct gttggggcat 14640 ctttctccat gttatcaaaa agccagcaca cgaagttatc tgtattttgc tggtaagcat 14700 taaacggtga tgttccaaaa atagatatgg aatcttgagg agacaatgac ttattagcat 14760 tgttttttat tgaaggggtt gataaaaact tgttttgcaa gttaatttgc tggtcgcttt 14820 caggaatggt aatcgagcct gaaatggagt tatttcgacg actagtggta aacatgtaat 14880 tgtttcccgt ctgtgcaatg gcagattgta gaccttcatt gaaattatcg gaaattatgg 14940 gctggtcagg taatatgggt tgatcgatat ggcttttgag gtctgtataa gcagcatcct 15000 gaacgtcggc ttcgacatat gagggaaaag gtaattcttg atcggaagat gaaataagtg 15060 tcttatcatg tttaggatgc gtttggctgc cagcatcgtt ctgctttaca tgcttttggt 15120 taacatgtcg atttagcaca tcgctccttg taaacgaact ggagcagtga gggcaaataa 15180 aggctttcga gttggtatct ataattagaa attagcggtt ttattgaaac aaaagtcaat 15240 tgtagcaagt ttcagaaggt atgtttgcta ctacctatcc aatcccacat tgcacatacg 15300 agatcgaaaa tgccttcgtg catgctcttt cctagtgaaa gatttagtac agccttgaaa 15360 atcgcatttg taacgaatat ctccttcttg gtatgcacga ctttttttcg ccttggtcat 15420 gaagaaacgc aagtaacctc actttacaga aaaatagtga ttaaacagat tcaacgcaat 15480 gatagctaac acctatattc aaaattcgtg acaatacatt cagaaagaga aataagaaag 15540 aagaaaaatc tacttaattt ccctagtcgc tcaaggtcgt agttgtaaaa gacatttaaa 15600 ttagaggcgt acgactccgg atccgcggcg ggcaattctt cttatcgaaa taaaccttct 15660 ggctattata cagggacttg ttaccttata tctatactaa gaacccaagt aatgtcagag 15720 ccctcgtctt aagcacaaaa ttttcatcta attttcaaat aaatactatg tatttgagtg 15780 actaattgta ttggtcatct ggcttgcagt tgatatttga ataatagtta agctagcact 15840 acgcaagatc tataaacgca acattaaatt tccaattgct aagttttata tgtagattta 15900 tattttctat caacccgcct gttaaacact ggtatttatt tctatcttcc ctgtaaatca 15960 caacactttt ctgtgtgatc ttgttaattc aatgcccttt aagataagca tgagctaatt 16020 taatcgattc tgatgcagat cggtgaattg ttgtaatatt gaatacatca attcctgttc 16080 atcgctatgt tttaaccccc gctttatctc gtgatttagt gatacgttat agctcgataa 16140 tagcttgcgt agagggggtt ctggctcaaa ctacagctaa gctatctatc taatctcgca 16200 actcttagtc gctaatcggc aatgtatatt gaggtggata acgggggtac cggacttata 16260 gcattttggt acgggtttgt atcaatgtct aaatcaactg tgtgaaggat ttattcggac 16320 tatataagta gttagcgttg cacagctgtt tctttcgtac atttaaattc actttcactt 16380 gcgtaactta gctgtacata ggtttacagt ggtaaaggac aattgacgct tttaatcctt 16440 atactgtttt tttacgatta acatcttttg acggtataat ctaatttttg ttttttgttt 16500 ttttttattt aaaaacaaat tcgattttga cgcaaagtgt ggtattccgt aacatctgtt 16560 taatagcctt ttgacccgtt gatatattaa aatggcttcc aacgttgata aatttagctc 16620 tcgcttctat ctgaatgtca ataaggagga attgaagaag gagtatgttg gcaaaactat 16680 ccaacaagtt cctaccccag gctttgtgat cgacgaagcc atattcgaaa agaactgcaa 16740 tcgcatgctg gaccgtgcaa gtgatatagg tgttactttc agggctcatg tgaaaactca 16800 caaaacgatt gaaggaactt tgcttcaatt aggcgatgga agaactaaag cagtggtggt 16860 ttctacattg atggaggggt tttcattaat acctctcatt ttagaaggaa agattgatga 16920 tcttctttac ggtcttcctg tagctaaatc taggctccct gaattgtatg agctttctaa 16980 aattgtccca catttacgtc tgatgattga taatcccaaa caactagaca tattacgtga 17040 attcacttcc acattacctg atgatgcaaa accatggtcg atttttgtca agatcgatat 17100 gggtactcac cgggccggtg ttactaacga ctcacaagtt gttaaggatt tgatatcaac 17160 gatcttgtct gacaaatcgt tgtttgatct ttttggattc tactgtcacg ctggtcattc 17220 atatgcttct aggtctattg acgctgcttc tgagttcttg tgtgctgaaa ttgacgctgc 17280 taatactgct gctaagttcg ctacctccat tgatccttcc ttaaaactta ctttgtctgt 17340 tggtgcgacg cccaccgctc attccgtcag tccaaaggta aaagagttat tacctacttt 17400 gagtggaaaa cttgaagttc atgctggaaa ctatcccatg aacgatgttc agcaaatgat 17460 aaccaaatgc atcagccagg cggacgttgc cgattacgtg tttgcagaag tcattagcaa 17520 ttatccaggt agaaacggtg aacctggtga agttcttgtc aatgctggtg taattgccat 17580 gtctcgcgaa acctctccag aaggtgattt tggaattgta attactcctg gatttgagag 17640 tttttacgtc gacagattaa gtcaagaaca tggtatttta aaatccaaag atccaaaagc 17700 cactcttcct gacgcctctc aagttctttg catcatccct aatcattcat gtatcactgc 17760 tgctgcattc ccttggtatt acataaccaa aggctcagat gttatcactg atatttgggt 17820 cccttggaaa ggttggtaga tgacaagctg actaaattag ctttaataat agattcctga 17880 tcgtggttag atttctgctt aatacgccta gaatactttt caaaaaataa tgaattcaat 17940 atatcgcgga agttgtgttt ctcgaataat gtatattttt tgttgctgtt tattcagtac 18000 ttgctctcag ttgttcagct atttaccgaa aaggtatttc tgatatttcc gatctttcaa 18060 ttttacaacg taattacttg tatgtttttt taaaacacca ggaaaacgaa agatgtttgc 18120 agattaaaaa ttactactgg tattcaatat caaaataagg ctaaagatgt aaaggtcgca 18180 tgcaataaac tatatactcg gactgtgtca gtacaatttt actaacactt cataaatgct 18240 tcatagcaga gaggggcttt ttgcaaagcg atgaaatgaa taggaatgtt gaaaaatggc 18300 caatgaagga acgtattaaa tactatataa taatgttggc gaaagttaaa ttataataga 18360 taacataaaa agttgttgaa tagtgtcgat atatgattgc aaaggtagat caacgtggta 18420 acataatgct tttaatagtt cgtataggct gcttgccgag tttatgtcta atacgaaccg 18480 ctaaattctt tagcagtaaa agtcaaggcg gaatcaaaga tctctattgc tttgtgaatt 18540 tcctcatcgg ttactgtcaa cggcggagcg atgcggaaaa ctccaccaat tcccctcaaa 18600 tgaacgatgt tacagttcat acctaattcc aaacatttat ctccaattac agttcccaaa 18660 aaatcactag gtttgctagg atctgtacaa gaagcaattt caataccttg caacagaccc 18720 agaccgcgta catcaacaat caaaggatgc ttatccttta gacgaaggag atcggatcta 18780 agtagttctc ctgatatttt tgctttttca actaagttat ctcgttttac caccttcaaa 18840 actgtagagc ctatcgcagc tggaagggga tcggaagcat gagttgtata gaatacgaaa 18900 ccattgtcgt aacaaacttt ttcaatttct tcagatgtta ttactgcagc taaagcagta 18960 ccagctccca aagacttcga aagcgttaga atgtcaggaa cgataccgtg gtgttcgaat 19020 gaaaacattg atccagtcct tcctatacca gtttgagctt catcaataat gagtagcata 19080 ccacgttctt cacatttttt cttgagagcc tttaagtagc cctggggtaa ttcaataata 19140 ccaccggtac tgagaatggt ttctacaatc atgcaagcta atgaaccagt cgattgtttg 19200 tcaagcatgt aaaaagagta gtcaagctcc ttttgccaat cgtaattacc tttggcatct 19260 ctgaatggag ataattttgg atttggttct ggaatggtat atgatccggg cagtgctgga 19320 ccatagccgc gtcgtgctgc agcaaaagta agactagccg cgcctccagt aacgccatgc 19380 catgaagaag agaaagcaac gcattcgtat ttatttgtat aaactttcgc catacgaagt 19440 gctgcctcat tcgcttcacc tccagtacta agaaaaagtg ttttgtcaag accgtcggga 19500 agtaaatcac tcaattcagt tgcaagttgt acgactggag ggctcaaaaa cccactgaaa 19560 agatgaacca attttggaag gtttttttcg atacaagctg tgatatcagg atgagaatga 19620 cctaaaatgg cactcatttg accagaagta aaatccaata tagcgttatc ctgttcatcg 19680 taaacacaac atcctttagc tcgtacaatt atttttggtg caaaatcacc gccatatcga 19740 attagggatt tgttggcttg gttccaaaat gttaccgggt ccaagatgct attgttactt 19800 acatgagaac tcatgtttat agtcaaattt ttaaaattat ctctttctca agaaactcta 19860 acctatttta tataaataca taataaggtc ctgttcgtga atgtagcatg agatagacac 19920 tctgcccaag ttaacgagat aatcggataa taaaatccgt aagttatatg ttcatattta 19980 tgcgcaaaga taataaacgg tcaataaaac ccgcatattt gctccatgta gaactacaaa 20040 aaaagagact taaaacaaaa gatacttgtg ctaaaccgtt tccaactaat tagtttattt 20100 acacattaac attaaatgca ccattctttc tacgttatgt gtgcataaat taagacaaga 20160 aaactccgtg gtcaggattg caaacgtaca tattagaaat ctcaaaagat ctatcaagcc 20220 aaagtaaatt aaacaagtaa acccagattt tgttgaacac tgaacaaata agatgactgt 20280 gcagacagcg gagaggacaa taacacttgt ccaggctatc tggccaaaac tacgaaaaga 20340 ggctgaaaag caatgtgaag ttaatccatg gttagccaaa gaccttgcga gaaaaatctt 20400 gagtaaaaaa actttgaggg agtctttgag ctgtgtttta gctcttccac ttgaccatgt 20460 tactgggagt tcagaatcaa tggaaaactg gttctacagt attctagggc tcaatgatga 20520 aaagataatt cgatcggcca tgatagactt ggatagattg tatacgacga atcctgcgtg 20580 cccggatctc attagtgcat ttctctcatt tcgaggattt catgccttgc aattgtatcg 20640 catagctcac ggtctttgga gcgaaggaga taaaacatcc gccgtgcttg ttcaaaattg 20700 gacggccgtg gcatatggtg ttgacatcca tccggctgcc agcattggag atggcttgtt 20760 tcttgaccac gccttgggta tagtgattgg tgagacagcg attgtagagg atggtgttag 20820 tatttggcac aatgtgacat tgggaagcac atttaaggat agtggagctc gtcatcccgt 20880 catacgcaag aatgctatgc tttgcactgg agccacagtg cttggtagag ttgaagtagg 20940 tgagaatgct gttgtagcag caggtgcttt agtgacaaaa gatgtagcac ctaaccgact 21000 tgcccttggt tctcctgcgc gcgatgtagg acctgtaccg caatacttcg gtgcccttac 21060 aaatccaaac tgtacaaata aatagagaaa atgaacatgc cgcatgattt acataatctt 21120 tttgtataaa attaaattaa ttaataaatt tttatataaa acaatcaaaa tagaaaaaca 21180 ttttcgcaaa ttcttccact aactccattc ttcttccttt cagtatgata ttcatctaca 21240 tgtagtgtac cttgtatcac aataaccacc ataacgaacg tttgagcaat agtcaaaacg 21300 gtatctgatg agcccggcag ttgttccgct ctcatttcta gtcgattgcc gtattacgtt 21360 aatgtggatc agtcacgttg caggattaga cgatgcacga tgtaaattca agctaatcaa 21420 aacaatgtgt taaagattac caaatttggt gtattgctac aatcgagatc cagtgtatca 21480 ataccaagaa ggttaactga taaacttaag cgtaatgtca aaaaatacaa gcaagcaatt 21540 gtgataagca cagtttggtg ttgtgtttca cagttcgctg ttgtgaattc tctagttaca 21600 cataagtcaa gtcgttgagg cattgactac aaaacattat aaacttgtta gcttgatgtc 21660 aaggaagcca caacattaag tgactttcgt tgcactttgg ttgatcaaca tgtgttttat 21720 ggagttgata gtagatctaa caatttcaga cccattatca actagggatt tcaagtcggc 21780 cgcaataaga cacccatttt actcaaatcg tcctctttag caagtactct tccactatcc 21840 accaaacaaa acgatacatc agacaacaaa gtgcaacaaa cactgccacc tggaaacgac 21900 gagtttcgca taaaaaaaaa ccaatattag acaatctcag caacaagcca acattcattt 21960 attctctcaa cttgactata tcagtataac attttgtaag ccctaccatg agttgtttaa 22020 cgataatgaa actatcacaa tcccgtttaa caatggctag caaaagtata tgcaaaatgc 22080 ataaatactg gtttcttaga aattgtacga ttgtgtactt ctccattttt aacttatcta 22140 ctatgtctag tatgtgttat caacaagcat tttgattgga tacaactcct taaaagtcgt 22200 ttaaatatcc ctcattggac attcaactta aaataagagc atatcttcca ttctgatttg 22260 acgtctccgg atttataaga gcgactaatc tgcgattgat aaccacttga gcatcgcatc 22320 tgtaaattag gaaggcgagg cactttgacg cactgatcgc ctcctggtcg ttttatagaa 22380 agaaggctag gaaagtagaa gaaaagctgt ggaaatcata gaatttgcat tgaaaaagaa 22440 agaaaagaga attatttact tactatggga tttattgaaa accatcaagt gtcaaatgca 22500 tcctttactt acaaaggatt tgattttggg aacaaagaga aatacacttc ctcacgcctc 22560 tactatcatt ataccacaaa atagcattca acaactactg gacaacaacg tgatttcagg 22620 aggcaacgct ttgcaggctt ggcaaaaatt gttcttatct tgtaaattga atgaaaaaat 22680 gggatatcag aataggtaaa tttgattgta aagtcgacta tatttatcag aaaaaaatga 22740 ttttgcctat ataagcgctt gaattccttt aacaaaaaag cgccatcaaa caaaaaatta 22800 aaatgaataa ttacggggtc tcttccatag gcacaagtct tacccctagt cccactgggt 22860 caatcgacga gtatacttcg aaagaagtga agcatcccga agatgtgaaa gtggatgcca 22920 gctatgaaaa ggaagaagtt ggatatggag agctcgaggt ggttcccgaa aggggaaact 22980 tgtttcagcg ttggtatcgt tcttttcttc ctcctgaaga tggaaaacct caaaaactta 23040 agcgtactct tactgcaaga cacattcaga tgattggtat cggtggtgca attggtactg 23100 gtgtgtgggt tggtagtaaa aacacccttc gtgagggtgg tgctgcttcg gttttaatct 23160 gttatagctt ggttggatct atggtattga tgactgtata ctcattgggt gaattggctg 23220 ttgcattccc catcaatggt agttttcaca cttatggtac tcgtttcatt cacccctcat 23280 ggggcttcac tcttggttgg aattatttgg caagtttcct ggctacatat ccattggaac 23340 tcatcacggc gtcaatttgt ttgcagtttt ggataaatat aaattccggt atttggatta 23400 ctgtgtttat agctttgctg tgcttcgtca acatgttcgg tgtacgaggt tatggtgagg 23460 tagaattctt tgtctcttcc cttaaagtta tggctatggt tggttttatc atctgtggta 23520 ttgtcatcga ctgtggtggt gtaagaaccg accatcgagg ctacattggt gctactatct 23580 ttagaaaaaa tgcctttatt catggatttc atggtttctg ctctgtcttt tccaccgctg 23640 ctttctccta tgctggtact gagtatatcg gtattgctgc ttctgagaca aagaaccctg 23700 caaaagcatt cccaaaagct gtcaagcaag tctttattcg tgtttcccta ttttacatct 23760 tagccctttt cgtcgttagt ctgttaatta gtggacgtga tgaaagattg accaccctta 23820 gcgcaactgc tgcaagtccc tttattttgg cccttatgga tgccaagatt cgtggattgc 23880 ctcatgtcct gaacgctgtt atcttaattt ccgtgcttac tgcagctaat ggtattactt 23940 atactggaag tcgtactttg cactccatgg ctgaacaagg tcatgcacca aaatggttca 24000 aatatgttga tcgtgaaggt agacctctat tagcaatggc atttgttctt tgcttcggtg 24060 cattgggcta catttgtgaa tctgcccaaa gtgataccgt ctttgactgg cttctttcca 24120 tttccaactt agccactctc tttgtatggt tgagtattaa cgtttcctac ataatttaca 24180 gattggcatt taaaaagcaa ggcaagtcat acgacgaagt aggctaccac tctcctttcg 24240 gaatatatgg tgcttgctat ggagctttta tcattattct tgtttttatc actgagtttt 24300 acgtatccat tttccctatt ggtgcctctc cggatgccgg agcattcttt caaagctacc 24360 tctgtttccc tgtagtcgtt attgtcttca ttgcccatgc tttaattacc cgccaaaagt 24420 tccgtaagtt atctgaaatt gacttggata ctggcttcag caagtacgat cgtttggaag 24480 aatcagataa gggaccaatg actgccaaga gtctcgccaa atccgtccta tctttctgcg 24540 tttaagcaac taaaatgata tccttcgttc atatttatat ttttgaacct caaactcttt 24600 tcttgttttt aattctattt tttgcataat atacgaattt ttttttattc taataaaacg 24660 atcagttttt tctcattctg aatggttaga atgcaaattg ccttagtatt tgtttattaa 24720 aatggtaatc tagctaattt acccgtaaag tttgttgagt aaaatacgat atgtacaatt 24780 tagcaataac tgatatgata atcgttaacc aaaattttgg gataagtcct tgaattattc 24840 tgtaacttta gagcctataa actaatattc agacatctca attagttgtg ctatcaaatt 24900 ccatatccct taaaactcaa agaactttca acaattacag ggcctgtatt gcaagtacga 24960 ttatatagaa tatttaaaac aacacttatt ttaatatctt gaatcttcaa tgtacaattc 25020 tttcatgcag aactcctaac aaatgggatt ttttaatttg aatatatagt ttttgatatg 25080 tttattatat aatgagtttt taaaattgcg atcgttatat tgctagcgaa gtgttcatta 25140 gcattaaact caaagctagg cggtatttaa gcgaattgcg aaatgcccaa attaaggtga 25200 gtaattactt atgatctcgt gtggaagtaa tgcaatgaaa tatatatgat ctatcataat 25260 ttctaaagct aatacctggc tgatgtaata tcaaatgcta gcttagtagt gaactgagga 25320 gctttgattc ggttaggtct attataatta ttgcaaccaa cagatagtgt caacaaatat 25380 caaataaatt gtgtcaatac tgtcaaaatc taaatcatat aggatatatt taaggacctt 25440 ttgacgaggt gatattttat ataccatatg gcatattgtg taataccttc aatatcattg 25500 ctattaatag aaatgcgttg taaagtattg cttctcatga ttaaatataa aaaaatgtag 25560 aaagaattaa tagaaatagt gttaaaattg aaacatatat acaactagca cggggtttga 25620 tttaaaaaag agaagattca tatcttgata ttaaacatgt gttttgatcg atctgttaaa 25680 gaaatattgt acaatattac taagcattca taaaattgta tctataaatt agtttgagtc 25740 tttaactccg aaaacgaatt tctcaagctg caaccagtaa tcatggtaat cttgctaact 25800 atttttttat gtgacaacaa ttttaccaag ttcaatatgt tgggacaact ctcataacag 25860 ggcaatcttg attaaaatca caaattgagc tcaattgata cagaatcttt aggttcgctt 25920 tttatatttg gtatcaccac tcaccattgc aacaataatc tcgattattt ccaatgggat 25980 tttgaactcc tttagtcata aatatcagca tattataatt caattaattc ttttaggaaa 26040 tacgtatggc acctccaacg ccataatttc ttgtatgaaa cttacactga tatgactgag 26100 taaacgcaat gaacaattct gtaatggctg tacatcaaaa attcgatatt aaataatttt 26160 taagacttca atgtataaaa ttactaaata agcttctaaa atagcctatt ataatggggt 26220 ggacactaag atagtcgaaa aatgaaatat caaaatgcaa cttttctcta catagagagc 26280 aatgaaaaaa atacttcatt tttggtttaa aattattttt ttatagattc ataaagtgct 26340 ctattatgat aatgattaaa ttgatttaaa cagatttgaa atttgcattt tgcttgccat 26400 cattatagct tagtataacg cgtggcctac tatatagttg gctggacatc acataatagc 26460 aatctatata atgaaataga aaaatacaaa taggtgtctg acagaaagaa ttttaaagaa 26520 gcaaccgtcg tgcaacaaat tatattaaat gtatgtttta tgtggcttca aagcaatgaa 26580 ataactagct gtttatagct aacaagacta tgtggactcc attcagatga taatgagctc 26640 acatagaatc atgagctcac atttttagca gtaacgcaag tttacacaat tacacaatct 26700 cctagctaaa ggtcgcagtt attctggaat acggaaatgg cgggggcatt cttagatact 26760 gaagtttcca gctgtatgat gggggtacct actaattaac gaaggatatt tgtaaagata 26820 agattgccat ggagcaaaaa gatctaaaga tttattatat atatgagcct gctgcatcta 26880 atttcaatgg gtcagattcc tttttgagtt ctgcgtttgt atttgtgttt tttttatcat 26940 gagcaaagtt cctattaaca gttccaagtt gtcatgtgga ggaccttata atcaagcagt 27000 taagtctggc ggtctcatct tttgctccgg tcaagctgct gttaaggatg gaaatttcgt 27060 cccaggtaca attcaagaac aaacacgtct taccattgaa aaccttgcag aggttctcag 27120 agtcgcaggt agcagccttg aaaagttagt caaggttaac atttttctga ctgatattga 27180 cgatttcgct gctatgaatg aggtttacaa agaaatgcta cctgatccaa tgccggctcg 27240 tactactgtt gcgtaagttt taaaaaaaaa gaattaaaat tagaaaggat agtatgctaa 27300 ttatctagtg ctggtaaaat tcctctatct agtaaaggtg gtaaaattga aatcgaatgt 27360 attgcggcag agtaatattc agcgatttca ttttcatttg gctattatga aatgacgttt 27420 ggttagaaaa acaaaagttc tccttatcgt gaatagctct aataaagacc aacatttttt 27480 tttctatgtt tcggtataag agtgcgcata atcgaatgta tttccagaaa tttcactgaa 27540 attcgatcga atcattaaaa tcagtaatta aacaaattgt gtcatttaga ctggcaaatt 27600 ccaactgatc gtccagttgt tgctaaacgc acctgttgac gtaaaagctt ctaagtttgt 27660 tagaacaagt tctttagtat cttcaagata actgaagctt tctacttgta cgccttcaaa 27720 ataaacacca attggcgcac atggaaggcc tataatggtt attttggaaa gtggttcatg 27780 aacttgtaaa tctccgtaac tctcaattga cagtgagtct ccgttagcaa caaatttcac 27840 aaaaagtgtt gattcttgtt gaatagatac tccatcatca acatacaagg atc 27893 //