ID SPAC1006 standard; DNA; FUN; 26399 BP. XX AC AL132828; XX SV AL132828.1 XX DT 08-NOV-1999 (Rel. 61, Created) DT 28-FEB-2002 (Rel. 70, Last updated, Version 2) XX DE S.pombe chromosome I cosmid c1006. XX KW CNH domain; coiled-coil; DEAD/DEAH box helicase; DEP domain; etd1; KW eukaryotic initiation factor 4a; G-beta repeat; glycosyltransferase; KW helicase c; peptidase; protein kinase; rho1 GDP-GTP exchange protein; KW RhoGEF domain; Subtilase family; TF1 LTR; WD domain; WD40; win1. XX OS Schizosaccharomyces pombe (fission yeast) OC Eukaryota; Fungi; Ascomycota; Schizosaccharomycetes; OC Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces. XX RN [1] RP 1-26399 RA McDougall R.C., Rajandream M.A., Barrell B.G., Simmonds M., Churcher C.M.; RT ; RL Submitted (08-NOV-1999) to the EMBL/GenBank/DDBJ databases. RL European Schizosaccharomyces genome sequencing project, Sanger Centre, The RL Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SA, E-mail: RL barrell@sanger.ac.uk XX DR GOA; O74304; O74304. DR GOA; P47943; P47943. DR GOA; Q9UTR4; Q9UTR4. DR GOA; Q9UTR5; Q9UTR5. DR GOA; Q9UTR6; Q9UTR6. DR GOA; Q9UTS0; Q9UTS0. DR SPTREMBL; Q9UTR5; Q9UTR5. DR SPTREMBL; Q9UTR7; Q9UTR7. DR SPTREMBL; Q9UTR8; Q9UTR8. DR SPTREMBL; Q9UTR9; Q9UTR9. DR SPTREMBL; Q9UTS0; Q9UTS0. DR SWISS-PROT; O74304; WIN1_SCHPO. DR SWISS-PROT; P47943; IF4A_SCHPO. DR SWISS-PROT; Q9UTR4; ETD1_SCHPO. DR SWISS-PROT; Q9UTR6; OCH1_SCHPO. XX CC Notes: CC Details of yeast sequencing at the Sanger Centre are available on CC the World Wide Web. CC (URL, http://www.sanger.ac.uk/Projects/S_pombe/) CC During 1995 to 1996 about 66% of S. pombe chromosome 1 was sequenced CC by the Sanger Centre. The sequencing of the S. pombe genome is now CC being continued with funding from The European Commission. CC Fourteen European sequencing laboratories, including the Sanger Centre, CC are participating in the project. CC Protein coding regions (CDS) have been predicted with the help CC of computer analysis using the Genefinder program in PomBase CC (an ACEDB database) with additional predictions for the CC branch-acceptor sites supplied by the program Sp3splice. CC CAUTION: It is possible that for any individual CDS we may have CC underestimated or overestimated the number of introns/exons or CC we may not have chosen the correct splice donor/acceptor sites. CC CDS are numbered using the following system eg SPBC25H2.01c. CC SP (S. pombe), B (chromosome 2), c25H2 (cosmid name), CC .01 (first CDS), c (complementary strand). CC The more significant matches with motifs in the PROSITE CC database are also included but some of these may be fortuitous. CC The length in codons is given for each CDS. CC IMPORTANT: This sequence MAY NOT be the entire insert of CC the sequenced clone. It may be shorter because we only CC sequence overlapping sections once, or longer, because we CC arrange for a small overlap between neighbouring submissions. CC Cosmid c1006 is overlapped at the 5' end by cosmid c2E12, CC EMBL entry SPAC2E12, accession number Z69726. XX FH Key Location/Qualifiers FH FT source 1..26399 FT /chromosome="I" FT /db_xref="taxon:4896" FT /organism="Schizosaccharomyces pombe" FT /strain="972h-" FT /clone="cosmid c1006" FT /map="IR" FT misc_feature complement(1..92) FT /note="nominal overlap with cosmid SPAC2E12, EM:Z69726 S. FT pombe chromosome 1" FT LTR complement(276..623) FT /note="TF1 type LTR" FT CDS 1701..3056 FT /db_xref="GOA:Q9UTS0" FT /db_xref="SPTREMBL:Q9UTS0" FT /note="SPAC1006.01, len:451, SIMILARITY:Schizosaccharomyces FT pombe, ISP6_SCHPO, sexual differentiation process putative FT subtilase-type proteinaseisp6, (467 aa), fasta scores: opt: FT 1138, E():0, (45.7% identity in 398 aa)" FT /gene="SPAC1006.01" FT /product="putative subtilase-type peptidase" FT /protein_id="CAB60231.1" FT /translation="MRVSWISGLLLVAHLAPSSAFNPLRFFLDDTFSSGATEEHFMGPS FT DDGFALQQPTNYDPSMPFPLDESASAAVDAVSNNYIVMFKPSVDKSKLEQHHRWIEHLH FT EKRSLDFKDVSTFLMKHTFEIGDAFLGYAGRFSPWLVAELQKHPDIALVEPDRVMHVMT FT EQTFAPWGLARVSHRKKLGFFTMTRYQYNETAGEGVTAYVIDTGINIEHQDFQGRATWG FT ATIPTGEGEVDDHGHGTHVAGTIAGKTFGVSKNAKLVAVKVMRADGTGTVSDIIKGIEF FT AFKQSKKDKESIASVVNMSIGGDASTALDLAVNAAIAGGLFFAVAAGNDAEDACGTSPA FT RVSNAMTVGASTWNDQIASFSNIGSCVDIFAPGSLILSDWIGSNRASMILSGTSMASPH FT VAGLAAYFISLDPSLANHPVELKKYMLKFALKDLLNGIPEDTPNVLAFNNYE" FT misc_feature 2181..3044 FT /note="Pfam match to entry PF00082 Peptidase_S8, Subtilase FT family," FT CDS 3557..4663 FT /db_xref="SPTREMBL:Q9UTR9" FT /note="SPAC1006.02, len:368, SIMILARITY some at C-terminal FT to:Arabidopsis thaliana, CAB43661, hypothetical 31.1 kD FT protein., (284 aa), fasta scores: opt: 229, E():3e-08, FT (38.8% identity in 121 aa)" FT /gene="SPAC1006.02" FT /product="WD repeat protein; no apparent S. cerevisiae FT ortholog" FT /protein_id="CAB60232.1" FT /translation="MVVPTPFYVLRGHSSSVTSVLFDANEYLYSGDEAGFVICWCLTSM FT RPKCAWRAHTKTILGMQIVKGGALCTHGRDCRLVTWKIDFNCMTDNFMSLSKLAELQNY FT GPEASSETEKSSAFISIHSNIVVNSLTFCPFSYSPQSKIVVLCNTLNFEELDVYDDESL FT YHPQTHKEDCGKRLQTRIQPEESVGKTGSVMSTSVTVTDEKYVLLAAGYESGHVVQYIC FT SLENVKTVTLDFKAVWKMVYAYKSHSQPVLSVEYAGSKLFSTGADDCICLHPTPSSIAD FT DLGSLPHPIFRKTKHCGQQNIRIRSDNKILATAGWDGRGRVYSCQTLAPLAVLKYHSDG FT INSLAFHPGSNVIALASKDTRISLWKLY" FT misc_feature 3566..3679 FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat," FT misc_feature 4268..4378 FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat," FT misc_feature 4538..4654 FT /note="Pfam match to entry PF00400 WD40, WD domain, G-beta FT repeat," FT CDS join(complement(7589..7733),complement(7250..7310), FT complement(5317..7049),complement(5073..5278)) FT /db_xref="SPTREMBL:Q9UTR8" FT /note="SPAC1006.03c, len:714" FT /gene="SPAC1006.03c" FT /product="hypothetical protein; sequence orphan; predicted FT coiled-coil" FT /protein_id="CAB60233.1" FT /translation="MSRSINLDELRKKALESKKKNEEDESNDSDKEDGEISEDDPVIDQ FT SNSVPPMKVPTFPEQIPQLPPFDRFPGTNANFFPFGAPFMLPPALMFGPNTVPFFPQTA FT SSNKTFSKRKRSSENSFNNRNKAKSSETSDSSNTSQSFKENRALKDTATSRPLALSSDT FT SYQKSEKAKSEKSPFLSTSKNSDANYSKTTNQKEAEKAVSQLFEVGVRFNDFIAEGIEP FT SVVHTLFLKLGLDSSSASSQGSLTLSADKAARSAKLRKIDSNLSDTHILPGDNGTPTVL FT PERKNLISLPLLKQDDWLSSSKPFGSSTPNVVIEFDSDDDGDDFSNSKIEQSNLEKPPS FT NSENGLTMSRSDYLALLRNKEEEIRRMTKLILRLESNKKPYRSPTSAADMKLPSVPVAA FT VDNKSKTHLDTFEKVVDLSSKADFVEAGPSISSSGASSSAATTNSDTTEQILEAPWLRK FT TEQIAVVHEEHPAQIKKSEIDILNNLIEKEEGELTKYQTLVKSKTEILTQLYTRKKQLL FT EQQGKGNVACLPKESDLSMDSITEVSAQADENSSQILSSKTSNAPNGTTETDFEDKVPL FT VDYISPFYRFKSYRFNQQFVERVPLKYRSLTYSNKIEPMKVFCKYETTGGVCNDDHCEA FT SHFRDIKMTGYDDEIIQDLSRYIEGNDEIEKESYKSGLDIVMKNTDENTDFVDVATRIV FT EYHNLWKSERMTIPVAKVSI" FT misc_feature complement(5279..5293) FT /note="ctaacctttatacag, splice branch and acceptor" FT misc_feature complement(5311..5316) FT /note="gtattt, splice donor sequence" FT misc_feature complement(7050..7061) FT /note="ctaacacactag, splice branch and acceptor" FT misc_feature complement(7244..7249) FT /note="gtaagc, splice donor sequence" FT misc_feature complement(7311..7322) FT /note="ttaacagtttag, splice branch and acceptor" FT misc_feature complement(7583..7588) FT /note="gtaagg, splice donor sequence" FT CDS complement(8997..11855) FT /db_xref="SPTREMBL:Q9UTR7" FT /note="SPAC1006.04c, len:952" FT /gene="SPAC1006.04c" FT /product="hypothetical protein; sequence orphan; predicted FT coiled-coil" FT /protein_id="CAB60234.1" FT /translation="MTKETHENHLRTHNGIFPVSLLSTQARQLLNFKLKSPSYYLLNSF FT KLLVKSEGNNQSTTADVTLTKSPNAYHASSAREEKDLQVSRRDTCFYCSRKIIKCICNE FT EHVGIESVQLKLILLLCQNLPNVTTNAKKYFSSLADGHNFTLTLYKFSLDNQTFSQLLS FT RFKSFATLTELLQVHNVMLQVNFSFQARQLNTEIQLRRCHSLEKTWKFLFGDYELPDVL FT KDMESSNSDWSDTSLKRIAYLCSLVEELKLHSSIMNDKYVCLVSKHNNALEDKFNSEAA FT RQLLQKSLSIVASNLKQAENKTISYEEKLSIAQNSINEIQTQNRDLKLETEKLQDQIKA FT LLERNQSLQEALETVKNDEKNLREMNANYETEMKEARQKLNNKEALISHYDDDFRAKEL FT KISRLSESLREKAGLLEFQSSVSEQRDLLYQEQIQSSIKDMENVFRKNEYLMEELNELK FT NNLEVESSKVLRLDEEMKCLKDEQLSQFDTVFSLTDERDGLQKDLKNTKGNLDDEIGRS FT AFLKSQIRDQELTIEKLHDSLETLSQTNNSLQCEISEKNAELNSVNSKLSEGRAHLETA FT NKENEILKQQLELSESKLASLLNSYQSFINKKEHLYSFLQLVEPSFAKSDSSNATESQI FT SESVRKGISIFNLLFIVYKNVCSQAGINPSTKLEDLDEHTLSDELTYITKKFVQKDQEY FT QTKEIELRNYKITLQSLLEDKLIGVNTDCRSPSCSDFEQLGQESENNTSISGRVSKLVK FT SFNDSSSISNNTKISITKSPSGEKVSVFKEMSDIALRDMDKNRKLLGENVDVRNIVVQK FT DESLNIDLQNNAVVPELHFKEGMVYDSLENAYTYLAESKRMLANELQMKQEDLEKVILE FT LEAYKEIFLEEKQIPCEEFMPGKNAKSEKSLRSVFQEQLMRETKRVRKLEKVNSELKLH FT CFELSERLREREHTLQQTFGDK" FT CDS complement(13047..14237) FT /db_xref="GOA:Q9UTR6" FT /db_xref="SWISS-PROT:Q9UTR6" FT /note="SPAC1006.05c, len:366, SIMILARITY:Saccharomyces FT cerevisiae, HOC1_YEAST, putative glycosyltransferase hoc1 FT ., (396 aa), fasta scores: opt: 652, E():0, (33.5% identity FT in 334 aa)" FT /gene="och1" FT /gene="SPAC1006.05c" FT /product="1,6-mannosyltransferase; involved in the outer FT chain elongation of N-linked oligosaccharides" FT /protein_id="CAD24818.1" FT /translation="MLRLRLRSIVIGAAIAGSILLLFNHGSIEGMEDLTEISMLEDYTP FT EAANKDYVGQQEEEELLYDQPSYIEEEEDPDLEAYLSDLEREELEHSLEELDEENNYKL FT HLRYSFSQLQDFDEENEAVHMIVPKDTYEFEVPYHADIPKLIWQTSKDPFDREVMKYTR FT FWRINHPSYSHAVLDDEQSKALVISSFGDSSVSKISQAYAMMPLPVLKADFFRYLVLLA FT KGGIYSDIDTAPLKHINNWIPREYRKRNIRLIVGIEADPDRPDWNDYYARRVQFCQWTI FT AAAPGHPILWELVRRITDETWKLHDSKKLSKNGESVMEWTGPGIWTDAIMDYLNWQYGP FT FSVENITNLEEPYLVGDVLILPITAFSPGVGHMGSKSPNDPMAYVQHFFAGSWKDD" FT CDS join(14966..17468,17524..17945,17990..18541) FT /db_xref="GOA:Q9UTR5" FT /db_xref="SPTREMBL:Q9UTR5" FT /note="SPAC1006.06, len:1158, FT SIMILARITY:Schizosaccharomyces pombe, CAB39903, rho1 FT gdp-GTP exchange protein 1., (1334 aa), fasta scores: opt: FT 2655, E():0, (44.7% identity in 1118 aa)" FT /gene="SPAC1006.06" FT /product="putative rho1 GDP-GTP exchange protein" FT /protein_id="CAB60236.1" FT /translation="MLRNGAQNGNINSESHESFGKAAKGFRIFSSFSSSQKLFQRRSSG FT SITHSPTALSSTTSLNENDGNHFRPASSLSFSPSSLSRKDSGPGDGLEVNKKNNFYRRS FT SSTDDFGISHARSRKEIQSLGRPHTRQSFSVSDVSNGSSYPNIRKNSVHVNAPMPSFPE FT GSTAVLLKHHSGSKSASAISNIAPSHSNSTSSRRPYIHPAFLSQVAVEFRKRLNIGDRV FT KDGLLYKDAFLGSEAVDVLMHIVRTTDRNLALLLGRALDSQKMFHDVTYSHRLRDSLKE FT VYQYRRIISPPPGLSSMDSNGSSIENNFLYTKRRANTSDSFDSVLSDSSTTPTISSSVQ FT VNSLAFITSSLSAITKEPEAPETEYNPHGVFTLLTECYSSTCSRNRLCYSISCPRRLEQ FT QARLHLKVQPVLSGGSTSITDKQEEDHRLWSENVPKQVVDQIDVREWKRQEIIFEVIYT FT ERDFVRDLEYIRDFWIKPLSTSNVIPENNRQQFIRCVFHNIMQIHAVNSRLSNALNRTQ FT TLQPVVNTIGDLFLDYVPKFEPFIKYGANQAIAKFEFEREKSTNRNFANYVHEVERLRE FT SRKLELNGYLTKPTTRLARYPLLLSGVLKYTDKDNPDTENIPRVIEMIREFLTKLNYET FT GKTENRLSLLQLNEQLSCSPADRAKLTLFDPSRLLIFKGVVKLKASSYSNGDTENDIHM FT FLLDNFLLLCKIKIQMKRRVHKLHLRPLPLELLSISYIEDSPSRGSLPRRPSSALLTNP FT ISITKSNPPPVKAYGLQLVFIGARGFSISLYLNTLIARDQWKQHIEKQQDIIRKRHLVF FT ESRGICCQSWFTGNKLLCAVAYDAGRKLLFGTYKGLYISSRKSNNGSCLEPIFKLQLPN FT ISQLDVIEEHNVLLLLAEKILYELPLDALDSVEQINSKSLRRVTGHVSFVKTGFCMQRI FT LVCAVKSTVLNTTLRIYEADRALKNKKTQSLKKPFGNQATLKIFTEVQMPMEALSVHFL FT KTKLCVGSFKGFDIISLENAVFQSLLNPADTSFRFLEKREDIRPIAMFRLRGEFLLCYS FT DFAFFVNTNGWKSRQSWMINWEGQPQGCALCYPYILAFEPDFIEIRNAETAELVQIIMG FT QNIKLLTDGRGLISEGGEILYSTEPIPFSSGENPIVHSLILPPANAAGPAL" FT misc_feature 15599..15820 FT /note="Match to PF00610 DEP, Domain found in Dishevelled, FT Egl-10, and Pleckstrin Score 67.43" FT misc_feature 16316..16861 FT /note="Match to PF00621 RhoGEF, RhoGEF domain Score 96.61" FT misc_feature 17469..17474 FT /note="gtaagt, splice donor sequence" FT misc_feature 17509..17523 FT /note="ttaacagctctttag, splice branch and acceptor" FT misc_feature join(17921..17945,18012..18460) FT /note="Match to PF00780 CNH, CNH domain Score 84.47" FT misc_feature 17946..17951 FT /note="gtgagt, splice donor sequence" FT misc_feature 17975..17989 FT /note="ctaacatttttttag, splice branch and acceptor" FT CDS 19424..20602 FT /db_xref="GOA:P47943" FT /db_xref="SWISS-PROT:P47943" FT /note="SPAC1006.07, len:392" FT /gene="tif1" FT /gene="SPAC1006.07" FT /product="eukaryotic initiation factor 4a" FT /protein_id="CAB60237.1" FT /translation="MVDQLEDSVIETNYDEVIDTFDDMNLKPELLRGIYAYGFERPSAI FT QQRAIMPILGERDVLAQAQSGTGKTATFSISVLQKIDTSLKQCQALILAPTRELAQQIQ FT KVVVALGDLMNVECHACIGGTLVRDDMAALQAGVHVVVGTPGRVHDMIQRRALPTDAVQ FT MFVLDEADEMLSRGFKDQIYDIFQLLPPTAQVVLLSATMPQDVLEVTTKFMRDPIRILV FT KKDELTLEGIKQFYVAVEKEEWKLDTLCDLYETVTVTQAVIFCNTRRKVDWLTEQLTER FT DFTVSSMHGDMDQAQRDTLMHEFRTGSSRILITTDLLARGIDVQQVSLVINYDLPANRE FT NYIHRIGRGGRFGRKGVSINFVTNDDVRMMREIEQFYNTHIEEMPMNIADLI" FT misc_feature 19517..20128 FT /note="Match to PF00270 DEAD, DEAD/DEAH box helicase Score FT 203.51" FT misc_feature 20243..20482 FT /note="Match to PF00271 helicase_C, Helicases conserved FT C-terminal domain Score 133.65" FT CDS join(21950..22859,22922..23187) FT /db_xref="GOA:Q9UTR4" FT /db_xref="SWISS-PROT:Q9UTR4" FT /note="SPAC1006.08, len:371" FT /gene="etd1" FT /gene="SPAC1006.08" FT /product="required for septation" FT /protein_id="CAB60238.1" FT /translation="MGVVYGSQQNLSEYFYSSVNMAEVPDTFEENRGHSFEGVTLQRRH FT VKGMKSYGSDITPRRPKQLGLPKEVNTSECIDQGSWRKPSAFESLRSYSRKFSKRIFSF FT IGVESKSTVQRNASGADSTSLSHFTANEINKGNCKKTALSNEFNSANKGSKASGVGAEL FT PSVNGFIEGELHDDNETDSFRINELAKQIQETSLGATTQEDESSDGICWDELSTTSPES FT SKVSEPIIQDNTQTTHINNDSSDIRFSSRCDLFADDADSDWEQDFNVKFDSPLIIPETV FT NSAGHTVREQLFEVKEFTRSIKDLKDLYEKANSKDIYDKDSEILGEAKAILRLADPANY FT SDLKDEDAQNILSKYKVKLEGDSSLDFDASMLPGLNDHVHYLMSQLQLLLH" FT misc_feature 22860..22865 FT /note="gtaaga, splice donor sequence" FT misc_feature 22902..22921 FT /note="ctaactaaaaacacaaatag, splice branch and acceptor" FT CDS 24302..26399 FT /db_xref="GOA:O74304" FT /db_xref="SWISS-PROT:O74304" FT /note="SPAC1006.09," FT /partial FT /gene="win1" FT /gene="SPAC1006.09" FT /gene="SPAC1250.06c" FT /gene="SPAPJ730.01" FT /product="MAP kinase kinase kinase; G2/M phase transition" FT /protein_id="CAB60239.1" FT /translation="MENILDPSVVNSHILENGSRRSSINPILDSELRDKTFEKAHRRSL FT TLLSSFTSSMLELPNNGKEENHRRPSVARSSSDRSKASAKEDLFSEAFRMAEQPPAEAL FT TISTPVDPINIDELDRAYAVSPSDTSNLLHPPTSSSSIPIPIKNAGHSNLDHPIRPSLQ FT SSISSNRIIKSPGIKEDDYMHRGRSISSPMIDVEHINSTAVPSKTKNLPEKPKRSHKLR FT NSITFAKIEDHPERKSQLRRLSSSLKCFDPEYDYNDPSLSIRRDSSTYYFSNVNETYDE FT EDSDLDSETSTVNWVQSVLNLPSLLSDDLMANPKNKERFEWQYMLTSVLTGDIVRSEKL FT RLRKIASSREGRNSDYSDNLWMEIWCWLTHRSVDSYRENLKHLRTGMVDVLLAIMNFHW FT DESNELTPIVAVDNMLQKLDKYERLYPSRRSILQEHSLYASESFQHKLDVLTAYSNVTH FT ALEIQVNIIRSWVGNEEMDITKNTTNSINNVSQISNGPFVERFYRETGLIRAFEQRIMT FT NMNSVLSKVCNTIVTYADDLKSYGLPLIADDYMRLLSFPFRLIKEFLNLRLSCAENITS FT ISLFTIDSLLDDLRNTMKVAVHIIQQHTVLIKPFRDDSKFVDENQSLNNILVASLKFYF FT NLLHRKVRNGCALLHFKETEILEGEWDFLLAVCPHIEHGFQIMSKSLSSLVGEILTNIN FT RYLKD" XX SQ Sequence 26399 BP; 7863 A; 4932 C; 4755 G; 8849 T; 0 other; tcaactaatg aaatcggaaa actcgctgtt cctccttgtt gtattcacaa cttcattgtc 60 tttgttacat tcatttctcc ttcatcttga tccttaatga atcatactta attgtctttt 120 tttacttttg tttaatggtt tactttaata caaacaaaat taatgtttac aaaataatga 180 acagcataat aaaatattgt gattgaaaac gatggtttgt tatcgtaatg attatagtga 240 ctcattacaa tagtgagtat ttaatgtcgt agtaatgtta gctacgcagt ttgatatctg 300 ttttaacgat atttagaatt ccggtgagtt tttacttgcg atctacaatg tagcggtatg 360 caatatttaa ctaacaatgt atgtttattg ttataaaaag tctattagta ttggtcaccg 420 atatagctaa taactgaact gaggaacgag attcagtggt agctctattt gtaaccttct 480 tgatagctga tatcaatgtt tattcatgta tatagaaggg cagtctatcc gcatttatca 540 gtaaacggat cttaagtaat atcttaacat aggaaatgta gtgatacgca acgtagtgta 600 tcataagtgt ggtattgctg acagtatctg tgttaacaat attttgggct gtggagaatt 660 tgacttgtat ttcgttatat tgtaatatgt agctcctgca ggtagcaagt attataagta 720 ttcatatact taagctataa attaacttat aagatatctt taattggact tcgttcctcg 780 tgttcaattt aagatccttt taaaatcttt ttcatagaat ctacaatgtt ttctaaataa 840 accgatagtc ttttgatttt atcaataaga gattttagct ggtaattcca acgtaaagcg 900 tatagtgata tacaacgtaa tgaattgtag cgtatcttag aattgttggc atatgtacaa 960 tcgtactttg acaatatcaa tcaattgatc aatattgtct atcaccttga aagctaataa 1020 tgatatatga aaccaatata tatgtatata tatatataaa ctctttcctc gagctggaac 1080 aggaatcccc ttgttccctc ctacctttat ttcgttttca accttctaac ctcgttatgg 1140 taatattcat tttctaaatg tactgcctag tttctttcat ttgtgaagcg cttatgagct 1200 caatatcttg aaatatattt ttaaaataca aaaaacggag ttcttattag atcaacatta 1260 cagcactcat cgtgaatggt atagcttcgg cagcgtaata tgttactcgg gctacttcgt 1320 cagcctcctt atcctgtact acattaagta aacagctcac aacaacttaa cttcttcaca 1380 acacacttgc tttttttgag taatttcaac tgatttgcaa ttgacatttc cattgttttg 1440 tttttctttg ttgcattttt tcttttgcaa agctttatat ttgtatccat tacttgaaat 1500 cttgttggtt tctaaattcc tttctttttt tccgaattca ttttttcaaa gacactacgc 1560 ggttgcttga agctgaaaga gtttgctaat tgcttatttc aatctgcttt ttgaattact 1620 cttgattaaa gtacaagtct tcactttttt tttcgtgtga gcgtgtgtgt agaattcttc 1680 ttgttctcaa tttttgtatc atgagagttt cttggattag cggtctctta ttagtggcgc 1740 acctggctcc ttccagcgcc ttcaaccctt taaggttttt cctggatgac accttttcaa 1800 gcggtgctac tgaggaacat tttatgggcc cctctgatga tggttttgcg cttcagcagc 1860 ccaccaatta tgatccttct atgccatttc ctttagatga atcggcatca gccgctgtgg 1920 atgctgtgtc taataattac attgtcatgt ttaaaccttc tgttgacaaa tcgaagcttg 1980 agcaacatca tcgttggatt gagcatttac acgagaaacg atccttagat tttaaggatg 2040 tatctacctt tttaatgaag catacctttg aaattggaga cgcttttctt ggttatgctg 2100 gtcgtttttc tccttggttg gtggccgagt tgcaaaagca ccccgacatt gcccttgttg 2160 aacctgaccg tgttatgcat gttatgactg aacaaacttt tgcaccttgg ggtttggctc 2220 gtgtatctca tcgtaaaaaa ctcggttttt ttaccatgac tcgttaccaa tacaatgaga 2280 ctgccggtga aggtgttact gcatacgtta tcgatactgg tatcaacatt gagcaccaag 2340 attttcaagg ccgtgccact tggggtgcca ccattcccac tggagaaggc gaagtggatg 2400 atcatggtca tggcactcac gttgctggta ccattgcagg aaaaaccttt ggtgtatcta 2460 agaatgccaa acttgttgcc gttaaggtaa tgcgagccga tggtactggt accgtatcag 2520 atattattaa aggtatcgag tttgccttta agcaatctaa gaaagacaag gaatcaattg 2580 caagtgtcgt caatatgtcc atcggcggtg atgcaagtac tgctcttgat ctggctgtga 2640 atgccgctat tgccggtgga cttttctttg ccgttgctgc tggtaatgat gcagaggatg 2700 cttgcggtac ctctccagcc agagtttcca atgcaatgac tgttggtgct tctacttgga 2760 acgatcaaat tgcttctttt agcaatattg gatcttgcgt tgatatcttt gctcctggtt 2820 ctttaatttt gtctgattgg attggatcta acagggcttc tatgatcctt tctggtactt 2880 ctatggcttc tcctcatgtc gccggtttgg ctgcttattt tatctctctc gatccttcgc 2940 tggctaatca tcctgtggag ttgaagaagt atatgctgaa gtttgcccta aaagacttat 3000 taaatggcat tcctgaggac acacctaatg tccttgcctt caacaattat gagtaaacgc 3060 tagttatgtg tatgtaaatg ttagcttgat gaccttgatt gtttattttt tgatgctccg 3120 atacgaatga tcaattaacc aagttgttga atatctactg tcatcagacg aacaagctca 3180 gagtaatgac atttgttatg tttagcaatg aaatcattta aaacgatacc aatttgttct 3240 tttaggactg attttttttt gtaatgtcag gtatagtaga attttatttc attttcttat 3300 ctactacttt ttgcactatt gttatcgttc attcgtacta gtagtaaata tgtagtttga 3360 caagtatggt atatcacttg gtaaaaaaaa atgccttctg gattcaccgt tataattttg 3420 tcttataccg cttattaaaa ttgattccct taccaccaac aattcgtttt acagttcaat 3480 ttgtattgtt cccctatcct ctcagcttga tgattacaaa tatttgctca aagtggatgc 3540 tttaatttaa attttcatgg tagttcctac tccattttac gttttacgtg gtcattctag 3600 cagtgtcact agtgtacttt ttgacgctaa tgaatactta tattctggtg atgaggcagg 3660 ttttgtaatt tgttggtgtc ttactagtat gcgaccaaaa tgcgcctgga gagctcatac 3720 aaaaaccata ttgggcatgc aaatagtcaa gggaggagcc ttatgcactc acggtagaga 3780 ctgtcgtctc gtcacttgga aaatcgattt taattgcatg accgacaatt ttatgtcatt 3840 atcaaaacta gctgaacttc aaaattacgg tcctgaagcc tcttctgaaa ctgagaagag 3900 cagcgcattt atatctattc attccaatat cgttgttaat tccctaacct tttgcccctt 3960 ctcttactct cctcaatcta aaatagtagt tttatgcaat acattgaact ttgaagagct 4020 tgatgtatat gatgatgaat cattgtatca tcctcaaaca cacaaagagg attgcggaaa 4080 aagactacag acgagaattc agccagaaga gtctgttggt aaaacaggat cagtaatgtc 4140 aacctcagta accgttactg acgagaagta tgtactatta gctgccggtt acgaaagcgg 4200 tcatgtggtt cagtacatat gttcattaga aaatgtaaag actgttaccc tcgattttaa 4260 agctgtttgg aagatggttt acgcctacaa aagtcattct caaccagttt tatcggtaga 4320 gtacgctggt tccaaattat tttcaacggg tgctgatgac tgtatatgtc tgcatcctac 4380 tccttcatct atagctgatg atcttggtag tctgcctcat cctatattta gaaagacaaa 4440 gcattgtgga caacaaaata ttcgtatacg aagtgataac aagatattag caactgcagg 4500 atgggatggt cgaggtcgtg tttacagctg ccagacatta gctcctttag cggttttgaa 4560 atatcactcc gatggtatta atagtttggc ctttcatcca ggcagcaacg tgattgcgtt 4620 agctagtaaa gacaccagaa tatctctctg gaagttgtat tagggcaaaa gtttaggaca 4680 ttacagttac gtttaatcca tcatcatttt caagaaatca tttacttttg gtttgcagga 4740 ttcaattcat tcttattaca atacgcgcat ttttatcaat aaccattgaa atgattttaa 4800 acgtattaca tatattaaat atattaaata tcagactagt aaatgcttaa tcttccagta 4860 ttttgatatc gcctcaaata agatgagcga ttcatatgca agcatagaaa gtacgaaaga 4920 cataattcta acctgagcta tattaagtag tgacattagt tttataacgg caaagagcca 4980 ttgtttatgt atagtgatgt ttatagtaca aggacgtaat tttgacggtc aaaattttta 5040 cagttagttt gatgttgctt ggcagtttca atctaaatgg aaacctttgc aacaggaatt 5100 gtcattctct ccgacttcca aagattatga tattcgacga ttcgagtagc aacatcgacg 5160 aaatcggtgt tctcatcggt atttttcatg actatatcta aaccggattt ataagactct 5220 ttctcaattt catcatttcc ttcgatgtac cttgataaat cttgtataat ttcatcatct 5280 gtataaaggt tagtcaaaaa tcaacagcac aaataccata acccgtcatt ttaatgtcgc 5340 gaaaatgcga cgcctcgcaa tggtcatcat tacaaacacc accagtggtt tcgtatttac 5400 agaaaacttt catcggctct atcttattgc tgtaggtaag cgaccgatat ttcaacggta 5460 ctcgctcaac aaattgttga ttaaatcgat aagatttaaa gcggtaaaat ggagagatat 5520 aatcgacaag cggtacctta tcctcaaaat ctgtttccgt cgtcccattt ggcgcgtttg 5580 acgttttgga agacaaaatc tgtgatgagt tctcatctgc ttgggcggaa acctcggtta 5640 ttgagtccat acttaaatca gattctttag gtaaacatgc aacatttcct ttcccttgtt 5700 gttcgagtaa ctgttttttc ctagtgtaca attgtgttag aatctcagtt tttgatttca 5760 ccaaagtttg atattttgtt agttctcctt cctctttttc tattaagtta tttaaaatgt 5820 caatctcgga ttttttaatc tgtgcgggat gctcttcatg taccacagca atttgttccg 5880 tctttctgag ccaaggtgcc tctaatatct gctcagttgt atcagaattc gtagttgcag 5940 cactagacga ggctcctgac gagctaatag aaggtccagc ctccacaaaa tcggctttgg 6000 aactaagatc aacgactttt tcaaaggtat ccaagtgtgt tttagatttg ttgtcaaccg 6060 cagctacagg gacagatgga agtttcatat cggcggcaga agttggcgat ctatacggtt 6120 ttttattaga ctcaagccgt aagatcaact ttgtcattcg ccgtatttcc tcttctttat 6180 tgcgaagaag cgccaagtaa tctgaacgag acatagtaag accattttca ctatttgagg 6240 ggggcttttc taaattagat tgttctatct tcgaattcga aaagtcatct ccatcatcat 6300 cggaatcaaa ttcaataact acatttggag tcgaggagcc aaaaggcttc gaagaagata 6360 gccaatcgtc ctgcttcaaa agtggtaaag atataagatt ttttctttca ggaaggacgg 6420 taggtgtacc attatcgcca ggtaatatat gtgtgtcact aagattactg tcaatcttac 6480 gaagtttagc agacctagca gctttgtctg cagatagtgt cagacttcct tgggagctag 6540 cagaagagga atccagtccg agctttaaaa ataaagtatg aacaaccgaa ggctcgatgc 6600 cctcagcaat aaaatcgtta aagcgcactc ctacttcaaa caactgactc acagctttct 6660 ctgcttcctt ttgattagta gtcttggaat aatttgcatc agaattttta gatgttgaaa 6720 gaaaaggtga tttttctgat tttgcctttt cactcttttg ataagaagtg tcggatgata 6780 aagccaatgg tcggctagta gcggtatctt taagagcccg gttttcttta aatgactggg 6840 aagtattaga agaatccgat gtttcagaag acttcgcctt atttcggttg ttgaatgaat 6900 tctcagatga ccgtttgcgc ttcgaaaagg ttttgtttga ggaggcggtt tgaggaaaga 6960 aaggaactgt atttggtcca aacatcaaag ctggaggaag cataaaaggt gcgccaaatg 7020 gaaaaaaatt cgcgttagtt ccaggaaatc tagtgtgtta gttagataag acacctgatg 7080 ggttgaatgt attcaagttc gaaaaaaaaa aaggaaattt tacaaattgt cattctcgta 7140 atcccaaagt tggagttaaa ccgtacagaa cagcataact agcggagaat agctccgtag 7200 aaaagataaa taagctgcac tgacaggttt aatcaaatgc catgcttacc tatcaaaagg 7260 aggcaactga ggaatttgct caggaaaggt tggtactttc attggcggaa ctaaactgtt 7320 aaaaaaacga attcatttaa acggtgagaa aattgaaaag atggatatca aaacataatt 7380 tccaaataca tataaaaggc ttctgccagc tttatttttc tctctttaaa aaaaaaaaag 7440 ccacgcatat aaatagagat atgaaatgtt ctaaacgaat gcaagcaatc gtcgaggaaa 7500 actcaataaa atgcgaacaa gcctataaaa acaaaaagtc tcgtttcaca atatatttgt 7560 gtaaatttcc atctctaatc taccttacct gaatttgatt gatctataac aggatcgtct 7620 tcgctaattt cgccatcttc tttgtcagag tcattactct catcttcttc attcttcttt 7680 tttgattcta aagccttttt tcgcaactca tcgagattta ttgaccggga catttattta 7740 cagctaaaac tgggttagta gtgccaaatt tcaacagcag atgttttgtt tgtagtacca 7800 gttaagacag tgaaacgcga aaaacattaa atattattgc acataaagtt ttttcacctc 7860 agagcatgtt attccctaat aaagatattg atggttgaat actttcttat ttgttctaat 7920 gaactgtctg aaatatgcac taagactctt tatttacaaa acattcggaa ttagtctatt 7980 gaacaggtat actgaatgta gcaaatatat tttcaaacaa ttttaaaaag taacacaaga 8040 acagctaata tgttcagcct tattggcttg ctcatacgaa aagtgtagcg gtgattcaaa 8100 gctttcgcat ccaattatct tttgctagtt tacagcacaa atttacgcga aggtgaaata 8160 acatttttga gttatcaaat tatagcggga aatctgcttt taatggacta gtcagtaatt 8220 tagtagcggc cgccttgtct cataaataga aacatagaac atctggagaa gttcaagaaa 8280 aatagcgaaa atgagaaaac tgtgttttaa acctttgtcc aataatgata atgttttcta 8340 ctagcatatc cttctatgag cacatgagaa aaagaaatat tctttcgctc agttcggttt 8400 taacgttgga acagtctttg gcctttatta aaaacttgaa gttcataaac taaaaacaac 8460 aaaaacattg tgctttatgc aaatttcgtg tgcaataaaa gttcgggtat ccgtttatga 8520 tgttttagca cgaaagccga ctattgacag taacactggt aatagctctt tttactaaaa 8580 accctcatcg aaaaggtagt tccgtatctg attacaaggc cgatcgtgca aaaatactaa 8640 agaccgagga atatgtaatc gtgcagtttt ataacatact cttccgttgc ttaagttatt 8700 aatctgaatt tagtctgttt aatccgttac atgaaaaatt tagcctttca ggagcttgaa 8760 gaaatgattt aagatcaaaa cgctttcatg taatcaccta acaaaaatgc tagattttgt 8820 tattatttat tattgaaatt cccccataaa cctcgaaatt ttaagaccgg tcaagttatc 8880 atttgaggct aacaggcggc cttcaagcat ttaaaacgaa agaccgtatt catagattat 8940 ttattggtaa tctcaatgag gctagtacct ttgatctgtt actacttgcg aacatactat 9000 ttgtctccaa atgtttgctg tagtgtatgc tcgcgctccc tcaatcgttc agaaagttca 9060 aagcaatgca atttcaattc agagtttact ttttccaatt ttcgaactcg ctttgtttct 9120 ctcatcaact gctcttgaaa aactgaccgc agtgactttt cggattttgc gttcttacct 9180 ggcataaact cctcacaagg aatttgtttt tcttctaaga agatttcctt gtaagcttca 9240 agttctaaaa taactttttc aagatcttct tgcttcatct gaagttcatt tgctaacatg 9300 cgtttggatt cggccaaata agtatacgca ttttccaatg aatcgtatac catcccctcc 9360 ttgaagtgca gttcaggtac tacagcatta ttctgtaagt caatgttcaa tgactcatcc 9420 ttttggacaa caatatttct cacgtcaaca ttttctccca ataattttct gtttttatcc 9480 atatcgcgca gagctatgtc tgacatctct ttaaatacgg aaactttctc accagatggg 9540 gacttagtga ttgagatttt tgtgttgttg gaaatagaag atgaatcatt aaagcttttg 9600 actaatttac taacccttcc tgagatagaa gtattatttt cgctttcttg ccctagttgc 9660 tcaaagtctg aacaagaagg tgatctgcaa tcagtattta caccgataag cttatcttca 9720 agtaacgact gaagagtaat tttataattc cttaactcga tttccttcgt ttggtattct 9780 tgatcctttt gtacaaactt ttttgttata taagtcagct catcagaaag tgtatgttca 9840 tcaagatctt caagctttgt agatggatta attccagctt gagagcatac gtttttgtaa 9900 acaatgaaca aaagattaaa tattgaaatt ccttttcgta cactttcgga aatttgggat 9960 tcggtagcat tagatgaatc acttttagcg aacgatggct cgacaagctg taaaaaagaa 10020 tagaggtgct cttttttatt aataaatgat tgataagagt ttaacaaact ggctaatttg 10080 gattcactta actccaattg ctgcttcaat atctcattct ccttattcgc ggtttccagg 10140 tgtgctctac cttcagaaag tttggagttt actgaattta actctgcatt cttttcagaa 10200 atctcacact gtaaactatt gttagtttga cttaaagtct ccaaactgtc atggagcttc 10260 tcaatagtta gctcttgatc cctgatttgg ctttttaaaa atgcagagcg cccgatttca 10320 tcgtcaagat ttcccttagt gttttttaaa tccttctgta atccatcccg ttcatcagtc 10380 aaactaaaga ccgtgtcaaa ttgagagagt tgctcatcct ttaggcattt catttcttca 10440 tcaagtctca aaaccttact tgattccact tcaagattgt tctttaattc attaagttct 10500 tccataagat attcattttt tcgaaataca ttctccatat cctttattga cgactgtatt 10560 tgttcttgat aaagtagatc cctttgttca ctaacagaag actgaaactc caataagcct 10620 gctttttctc taagactttc ggaaagtctt gaaattttta attcttttgc tcgaaaatca 10680 tcatcataat gactaattaa tgcctccttg ttgtttaact tttgacgcgc ttctttcatc 10740 tcggtttcat aattggcgtt catttctctc agattttttt catcattttt aacagtttct 10800 agagcttctt gcaatgactg atttctttct agcaacgctt tgatttgatc ctgtaacttc 10860 tcggtttcaa gttttaaatc cctgttttgg gtttgaattt cattaataga attttgagct 10920 atagaaagct tttcttcata actgatagtt ttattttcgg cttgtttcaa atttgacgct 10980 actatactta gagatttctg caacaactga cgcgcggctt cactgttaaa cttgtcttcc 11040 aatgcgttgt tatgcttgga cacaaggcac acatacttgt cgttcataat agaagaatga 11100 agtttgagct cctcaacaag agaacataaa taggcaattc gtttcagaga tgtgtcactc 11160 caatcactat tcgatgactc catatctttt agaacatcag gtaattcata atcgccaaat 11220 aagaatttcc atgttttttc taacgaatgg catcgtcgta gttgaatttc tgtgtttagt 11280 tgccttgctt gaaaggaaaa gtttacttga agcataacat tgtgcacttg aagtagttca 11340 gtcaaagtag caaaagattt aaatcgagaa agtaattgag aaaatgtttg gttatctaaa 11400 gaaaatttat aaagcgtcaa agtgaaatta tggccatcag ccagtgaact gaaatatttt 11460 tttgcattag tagtaacatt tggtagattt tggcacaata gaagtataag tttaagctga 11520 actgattcaa tcccaacgtg ttcttcgttg catatgcatt tgataatttt tctactgcaa 11580 taaaagcaag tatcccgccg agaaacttgt aaatctttct cttctctagc gctggaagca 11640 tgataagcat ttggtgattt tgttaaagtt acatctgcag tggttgattg attattccct 11700 tccgatttaa ctaagagttt aaaactgttt aaaagataat aggaaggact ctttagcttg 11760 aaattcaaaa gttgacgcgc ttgagttgag agcaaagaaa caggaaatat cccgttatgc 11820 gtacgcaaat gattttcgtg agtttcttta gtcattaagt atttaatcaa ataagttagg 11880 cttttctaaa atataatttt gagcaagcaa tctaccaatt gtaagattta tcaacgatgc 11940 ttctaattcg aagatgtaaa tcctgcactt atagaaaaga aataacggaa aaaagaaata 12000 cttttaacat caattaggaa aagcattaaa ccttcaggtt gtaaatgcac tcaacaatcg 12060 tgtttgtgac agtgggaaat ggaggtaaat aaacactaca ataacttctt atatgggtgt 12120 ttaatgttct aaggtattca aagcaagggc gttagcatag ctttaaaaga taatagtaag 12180 tttattcaat tattgaaaca cttttcagtc tatttattta taataaaaat aatgtatagt 12240 tgaagctgta aagtgatgaa ctttgtcggt ccaaagtaaa caaatattat agaatacagc 12300 gctaatacta ctagcaaaat aaagtcacct tctgaaaaaa aatgtagttg caaagaaaga 12360 gagacaaacc tcaaaaattt aatgaagaaa tatgaggtcc tttaatccca agaagcattc 12420 atgcaagtct aaagacataa agtaattaca aagccgaaac aggtttatca ttcatcttca 12480 aatcttaggc ataatctctg tactactttg ataattcacc taagtataca gaaacgcttt 12540 ggggtcaata taccatcaca aaagagaaaa aaattgaaaa agactgattg tgatcagcgc 12600 aaaagtttta taaaattatt gaaagaaaca aacagcttta gaattcaaaa cagtttacaa 12660 gggaaaatat tatagtgctg agctataaaa cgcgttgatg aaagcgctga aaaaaaaaaa 12720 aaaaagaaag ttgatcatca ggacataagc attggcttca tataattcaa taatgtcacc 12780 aatattgcca acttgattgg ctaacgtaca aaatacatgc aaaattaatc gtaaagagat 12840 gtagaattat gagggaaaga ttaaatcaac cacgaaagaa acttttttgt ttgcgcaagc 12900 tataatttac aaaaattgct cgaacacaac ccgtaacagt ttccaaacca gatcaaatgc 12960 gtgtatttag tattatcgaa ttgcccggtt cgaacacttt aagcacatta taccaagaaa 13020 tgaccaccca cccacatttc aaacgatcaa tcatctttcc atgaaccggc aaagaaatgt 13080 tgaacatacg ccatcggatc atttggagac ttgctaccca tgtgaccgac accaggacta 13140 aatgcagtta tgggtaggat taaaacatct ccaacaagat aaggttcttc taaattggtg 13200 atattctcaa ccgagaaagg gccatactgc caatttaaat aatccataat ggcatcggtc 13260 caaatacctg gaccagtcca ctccattact gactcgccat ttttcgaaag cttctttgaa 13320 tcatgcagct tccaagtttc atcggtaatt ctacgaacaa gttcccaaag aattggatgg 13380 cctggtgcag cagctatggt ccactgacag aattgtacac gcctggcata gtagtcgttc 13440 caatcagggc ggtcgggatc tgcttcaatg ccaacgatca gtcgaatatt acgcttacga 13500 tattcacgag ggatccaatt gtttatatgc ttcaatggtg ccgtatcaat gtcgctataa 13560 ataccacctt ttgccaataa cactagatac cgaaagaaat cggccttcag aacaggcaga 13620 ggcatcattg catacgcttg tgaaatcttg gaaactgatg aatcgccaaa gctactgatg 13680 accaatgctt tagactgctc atcgtctaaa acagcatgag aataactggg atggttgatt 13740 ctccaaaacc gagtgtactt cataacctct ctatcaaaag ggtccttgga agtttgccat 13800 attaacttgg gaatgtcagc gtgataaggc acctcaaatt cataagtatc tttaggaacg 13860 atcatgtgta cagcttcatt ttcttcgtca aaatcttgaa gctgtgaaaa ggagtaccgt 13920 agatgaagtt tataattatt ttcttcatca agttcttcca agctgtgttc cagctcttcc 13980 ctctccaaat cgctcaagta agcttccaaa tctggatctt cttcttcttc aatgtaagac 14040 ggttgatcat acaaaagttc ctcctcctcc tgttgaccaa cataatcttt attagcggct 14100 tccggagtgt aatcctccaa catcgaaatc tctgtcaaat cttccattcc ttctatgcta 14160 ccatgattga ataacaacag tatggatccc gctatcgcag ctcctattac aatacttctc 14220 aatcggagtc tcaacatgct gaactcgtta tatgctaatg ctcaatgtat caattaatta 14280 cttagttcgt taacaaagac tcattaatgt gtacttaatg cagctaggat acagattttg 14340 cggtttttca tagaatcgca gcaaaacaca ggtgggcgct ctggctgagt ttgcgcagat 14400 gctcttactt taacttcgca caagcgaccc gaaaatcgaa gggctttaat gtgatattac 14460 tctataatag caacagccac acttgattgc ggtaccgtgc gtaatatcag tccaagtatt 14520 gtcggctgta gttaacggtg tgtgttaggt gtatgtacac aataacagaa aaaggttacc 14580 caaagcacca cccataatat agaagtgtaa gcagcgatcc acttcaaatc cgttcttttg 14640 agtatccaag ctgtttgaat aattggaaag ccggagaatt ggcattaata tacgtactcc 14700 ggcttctcgt gtataataag aggaatttgg tgaagtttcc atgttcaaat aagacgactt 14760 gtcttgtaga accttttatt gttgaaagta attggagcgt taaaaaaaaa ggtactactt 14820 gaatttgaaa aatatctttc ttctctttct gttgttgtgt cggtacggac gattggtatc 14880 agaaaagccc ctttgcatag cgccgttttt ctaaaacttg cgatacctcg agagggtagt 14940 aaaattagaa tcaacaaaca agaaaatgct tcgcaatgga gctcagaatg gaaatataaa 15000 ctctgagtct catgaatcgt ttggtaaagc agctaaagga tttcgtattt tttcatcatt 15060 tagcagtagc caaaaactgt tccaaagaag gagttctggc tctatcacac attctcctac 15120 cgctttatca tctaccacat cccttaatga aaatgatggc aatcattttc gtcctgcatc 15180 gagccttagc ttttctccct cttcgctatc cagaaaagat tcgggtcctg gagatggctt 15240 agaagttaat aaaaaaaata atttttatcg ccgttcttcc tccacagatg attttggcat 15300 ttctcatgca cgtagtagga aagaaataca atcgctcggt agaccccata ctcgccagtc 15360 gttttccgtc tctgatgtat ctaatggcag ttcttatcct aacattcgaa aaaatagcgt 15420 ccatgttaat gcacccatgc catcttttcc tgaaggatca actgccgtct tacttaagca 15480 tcactcaggc tccaagtctg catctgcgat ttcgaacatc gccccttcgc attccaattc 15540 tacctcatct cgtcgccctt atatacatcc ggcttttctt tctcaagtcg ccgttgagtt 15600 ccgaaagcgt cttaacatcg gtgaccgtgt gaaggatggt cttctttata aagatgcctt 15660 tcttggatcg gaagctgtcg atgtattgat gcatatagtt cggacgactg acaggaattt 15720 ggcgttactt ttaggaagag ccctggattc gcaaaagatg tttcatgacg ttacttactc 15780 tcatagactt cgcgactcgc tcaaggaagt ttaccagtac cgacgtatca tttctcctcc 15840 tcctggtctc tcctcgatgg attccaatgg atcgtcgatc gaaaataact ttctctacac 15900 aaaaagaaga gcgaacacgt ctgattcatt tgactctgtt ttatctgatt cttctacgac 15960 acctaccatc tcctcgtctg tacaggtaaa ttctttagct ttcatcacct catccctaag 16020 cgcaattact aaggagcctg aagctcctga aaccgaatac aatcctcatg gagtgtttac 16080 tcttttaacg gaatgctact cctctacatg ttctcgtaat cgcctttgct attctatatc 16140 ttgcccacgt cgactagagc agcaggcccg tctccatttg aaggtccaac ctgtattaag 16200 tgggggatca acttcgatta cagataaaca agaggaagat catcgtttat ggtcggaaaa 16260 tgttcctaag caagttgtag accagatcga tgtccgtgaa tggaaaagac aggaaatcat 16320 ttttgaggtt atttacacag aacgggactt cgtcagagac ctagagtata tacgtgactt 16380 ttggattaag cctctttcaa cctcaaatgt aataccagaa aacaaccgac aacaatttat 16440 acgttgcgtt tttcataata tcatgcaaat ccatgctgtc aattctcgtt tgtcaaatgc 16500 tctaaaccgt actcaaactc tgcaacctgt agttaacaca attggtgatc ttttcttaga 16560 ttatgttcct aaatttgagc cttttataaa atatggtgcc aatcaggcta ttgccaagtt 16620 tgaatttgag cgtgaaaaaa gtacgaatag gaattttgcg aattatgttc atgaagtgga 16680 aagattacga gagtctagaa aactagaact taatggttat ttgaccaagc ctacgactcg 16740 ccttgcgagg tatccgctac tattaagtgg agttcttaag tacactgata aagataatcc 16800 tgatacggaa aacattcctc gtgtaatcga aatgattcgt gaatttctta ctaagcttaa 16860 ctatgaaaca gggaagactg aaaatagact ctcgttgtta cagttaaacg aacagctttc 16920 ctgcagccct gcggatcgag caaaattaac attgtttgat ccatctcgct tattgatttt 16980 caaaggcgtc gtcaagctaa aagccagtag ttattcgaat ggggacactg aaaacgacat 17040 tcacatgttt ttactggaca attttctctt gttgtgtaag ataaagattc aaatgaaaag 17100 aagagttcat aaactgcatc tcaggccatt acctttagaa ttgttgtcga tttcttacat 17160 cgaagactcg ccatcgagag gtagccttcc gcgtcgacca tcttctgctt tgttaactaa 17220 tccaatttca attacaaaaa gtaatccacc tcctgttaaa gcatacggtt tgcagttagt 17280 atttattgga gcccgtggtt tttctataag tctttatctc aatacactga ttgctagaga 17340 ccaatggaaa caacacattg agaaacagca agatatcatt cgaaagcgtc atttggtatt 17400 tgaaagtcga ggcatatgtt gtcagtcctg gtttaccggc aacaagttat tatgtgccgt 17460 tgcctatggt aagtataata aacaatatgt taaagaagta aatgtttgtt aacagctctt 17520 tagatgcggg ccgtaaatta ctatttggaa cttacaaggg actatatatc tcttctcgaa 17580 aaagtaataa tggcagttgt cttgaaccca ttttcaagct gcaattacca aatatctctc 17640 aactagatgt aattgaggaa cataacgttc tattgctttt agccgagaag attttgtacg 17700 agttacctct ggacgctctt gattcagtag aacaaattaa ttcaaagtct ttgcgacgtg 17760 taacaggtca tgttagtttc gtcaaaacag gtttttgtat gcaaagaatt ttagtctgtg 17820 cggtaaagtc caccgtttta aatactacat tgaggattta tgaggctgat cgtgccttga 17880 agaacaaaaa gacccagtct ctaaaaaagc cttttggcaa tcaagcaact ttgaaaatat 17940 ttactgtgag ttacctcgtc gttctttctc tatactaaca tttttttagg aggtacaaat 18000 gccgatggaa gctttgtccg ttcactttct caagacaaag ctttgtgtgg gaagttttaa 18060 gggattcgat attataagtt tggaaaatgc cgtattccaa tctttgttaa atcctgctga 18120 tacttcattt agatttttag aaaagaggga agatattcga ccgattgcca tgtttcgctt 18180 aagaggagaa tttctcctct gttattcaga ttttgcattc tttgttaata cgaatggctg 18240 gaaatctagg caatcctgga tgattaattg ggagggccaa cctcaaggtt gcgctttgtg 18300 ttatccatat atcctggcat ttgagccgga cttcattgaa attaggaatg ccgaaacagc 18360 cgaactcgtt caaatcataa tgggacaaaa cattaaactt ttaactgatg gccgagggtt 18420 aattagtgaa ggaggtgaaa tactttacag cactgagcca attccatttt catctggaga 18480 aaatcctata gttcattctt taatacttcc tccagcaaat gcagcaggtc ctgcacttta 18540 gatcgtttat gacagtactg tcaacatttg tgcgaacttc tccttgagca ttttggaata 18600 ctatttacta ctccggacat cttttgcatg ccacatcaat tgattataat atatgctatt 18660 acaatctaag cttcaagaat ctatgaccct gcttcatctc tttaaggaat aactttaaaa 18720 attcctacgt acatatattt actatggttg agataatgct attgacgatt gtgtgtttta 18780 ttaaacgaat tgtgtctttt tcaatttgct caacattgca cgctgttttt gttacgaatc 18840 attctttttc catagattta ttatgcattt ctttagtcaa ctaataaaca acctctctgc 18900 attcagcata ttcattcatt atcttttatt gtgattgttt aaaatactca tgtgtaatcg 18960 ataacttttc atactattga agataacatg aacagtgtta caataataaa aaatgctttt 19020 atatgcattc caaactcctt aacatttttt atgttttagc attcaccaaa tattaccacg 19080 taaaatacac tttttcgcaa cgagttgctt atctgtatta aacagcatta acgcaggctt 19140 cgatagagtg tgcaggagtt tatcgccacg ttcagtaggg tttttcttgc tacatcattt 19200 tttagaagac atctaaaatc ttaaaagtaa agtgtgtaca taaatgtttt tataattttt 19260 ttaaatagat ttttcagtaa aagtctgtgt atttaaagta ctaaaataat caggaattat 19320 tacaattttt caggtgtgtg actgtgtgtt agagaaaata tttattacaa cccttcaact 19380 ttttttccac aacccactca cctagctaag caagattgct aaaatggtag accaactgga 19440 ggattcggtt attgaaacca actacgatga ggttattgac accttcgacg acatgaattt 19500 gaagcctgag cttctccgtg gtatttatgc ctacggtttt gagcgtcctt ctgccattca 19560 gcaaagagcc attatgccca ttttgggaga gcgtgatgtc cttgctcaag ctcaatctgg 19620 tactggtaag actgctacct tctcaatttc tgttttgcag aagattgaca ctagcttgaa 19680 gcaatgccaa gctcttatcc ttgctcctac ccgtgagctt gctcaacaaa tccaaaaggt 19740 tgttgttgct ttaggcgatc tcatgaatgt tgaatgccat gcttgtattg gtggtactct 19800 tgttcgtgat gatatggctg ccttgcaagc tggtgttcac gttgttgttg gtacaccagg 19860 tcgtgttcac gacatgattc aacgtcgtgc tcttcctacc gatgccgtcc aaatgtttgt 19920 tcttgatgag gctgatgaaa tgttgtcccg tggtttcaag gaccaaattt acgacatttt 19980 ccaacttttg cctcctactg ctcaagttgt tcttctttct gccaccatgc ctcaagatgt 20040 tttggaagtc accaccaaat ttatgcgtga tcccattcgt atccttgtta agaaagatga 20100 gcttaccttg gaaggtatca agcaattcta tgttgccgtt gaaaaggaag agtggaagct 20160 tgacactctt tgcgatcttt atgaaaccgt cactgttact caagccgtta ttttctgtaa 20220 tacccgtaga aaggtcgatt ggcttaccga gcagctcact gagcgtgatt ttaccgtctc 20280 ctccatgcac ggtgatatgg accaagctca acgtgatact ttgatgcatg agttccgtac 20340 tggttcttct cgtattctta tcaccaccga tcttcttgct cgtggtatcg atgtccaaca 20400 agtctccttg gttatcaact atgacttacc tgctaacaga gaaaactaca ttcaccgtat 20460 tggtcgtggt ggtcgtttcg gtcgtaaggg tgtttccatt aactttgtta ccaacgacga 20520 tgttcgcatg atgcgtgaga ttgaacaatt ctacaataca cacattgagg aaatgcctat 20580 gaacattgct gacttgattt aaaaaataca aaagtccttt cttctctttg ttctagatat 20640 ggaacgctcc gtgattgctc ttctcgcaac ccggcaaacc tcccgcaact taatttatct 20700 gcttttcttt gcccatgttt ttaatgcttc ttttatctgt gccggttgat agctgctcac 20760 catatggttt tttgtgagtc gtgttagtgt ttgctgagaa aggatttttt ttttcggcta 20820 cgctgtttat tcattaggtc acaaaataaa aggctggatt tggttgattt acatatattt 20880 actcttcttt tgagcctcgt gtagctgttc tgtgattact tttataaatg tgttgtagtt 20940 tggttagaag gtttgtcgtt tttttgtttt ttggtaaaac taaatgagtg aatagaggat 21000 gtcaatctgt attttggatt gaacttttat ttactgcgta tacctttgtg gaattaattt 21060 ttttgctcag agctaacgta tttgtgttaa ccgtaactgt ccagtcgtac ttttgtaagg 21120 aattaggaag ttccttttgc taaaagttaa atggtctgta gtaataaaca attctgctag 21180 gtaaaagtta ttattaatca ttgatccatt aacctattat attcgctatg tttatattaa 21240 ctgtgagatt aaaggttgca tcactttacg ctctcaaaaa cgtagcttta aactgcaaac 21300 attatttgac tagttttaaa gagtttgact tttaagtcaa tgtaatgaaa gaaaagaaga 21360 aaacaatgtt ttccctgcat caacagagtt agttgaagag tttatcgtaa gcaagtaaag 21420 aaagttgaaa ggcgtatagc aacttttgat gctaacattg tgctcatgaa cgagcagtgg 21480 ctttgaatct ttgtagagtc attcatcttt tcagtttttg gctaacttat ttattttaag 21540 ttgaacattt ttaatgaata aaacttgtaa tagacagtct tttccatttc ctagtctatc 21600 tctgctagca ttccatcttt acaaagccct atttaacgta accacgatta acgcgttata 21660 aagtatttat cagaattata tagcgcttaa acaacataac gaattgcgtt ctttgatgtt 21720 atagaacttt gtatttcctt ataaatcatt tacagattca tgttcaaaat tcgttatgtc 21780 gttctcatga cgaccgtttg tttactaaca aaagcgtggt cttgacgaaa gtgccttcta 21840 ccattattta cacacttgaa tgggttgacg cgtacagtct tttctctacg gcaataattc 21900 tttctttaat ttagcttaag agaaatatag atttacgagt atttcgtcaa tgggagttgt 21960 atacggcagt caacaaaatt taagtgaata tttctattct tctgtcaata tggcagaggt 22020 tccagatact ttcgaagaga ataggggtca ttcttttgaa ggtgtgactc tacaacgaag 22080 gcatgtgaaa ggcatgaaaa gttatggttc agatattaca ccgaggcgcc ctaaacagct 22140 tggattaccg aaagaagtta acacctccga atgcatagat caaggctcat ggaggaaacc 22200 ctcagcattt gaaagcttaa gaagttactc ccgaaaattt tctaaacgaa ttttttcatt 22260 cataggagtt gagtcaaaaa gtactgtaca acgcaacgct tcaggtgcag acagtacgtc 22320 gttgtctcac tttacggcga atgagataaa caaaggcaac tgtaaaaaaa ctgcgttaag 22380 taatgaattt aattcggcca ataaagggag caaggctagt ggtgtaggtg ctgaactacc 22440 ttcagttaat ggatttattg aaggtgagct tcatgatgat aatgagacag attcctttcg 22500 gataaatgaa ttagctaagc aaatccaaga aacttctttg ggtgcgacta cgcaagaaga 22560 tgagagttcg gatggtattt gctgggacga gttatcgact acttcgccag agtcgtcgaa 22620 agtgtcggaa cctatcattc aagacaatac gcaaacgact catataaata acgattcatc 22680 ggatattcga ttttcatctc gttgcgattt atttgcggac gatgcggatt cagattggga 22740 gcaggacttt aatgtgaaat tcgatagtcc attgataatt cccgaaacgg taaacagtgc 22800 aggacacacc gttcgagaac agctttttga ggtgaaggaa tttacgagat ccatcaaagg 22860 taagacattc atgtgttgta atgctttagt tttaaccgct gctaactaaa aacacaaata 22920 gacttaaaag atctttacga aaaggcaaat tccaaagata tttacgacaa ggactcagag 22980 attttaggag aggctaaggc tattctacgg ttagcggatc ctgcaaatta ttctgattta 23040 aaggatgagg acgcgcaaaa cattttatca aaatataaag ttaagttgga aggggattct 23100 tcattagatt tcgatgcgtc catgctacca gggctaaacg atcatgtgca ttatttaatg 23160 tcccaactcc aactattatt acactgagtt tctctttttg gctatttaat ccattaatgg 23220 aatgggaagt atctattttg ttatccaaag tgtcaaaatt tcgcttagga taatttcaat 23280 aattgtgaga acagtttcgc attggtggat agcaagtaaa ggtgaaactg gccattacaa 23340 cctttttata cttctgcatc ttaagaagct tttggtttta ttgtaaattt ctttcgtttt 23400 ctctttttaa taaatctatt ttgcaataat atttcggaaa aagtactaga cagatgtttt 23460 gtcttttgtg aatattagtc caacctttat tctgtgataa aaagatttta ttaaattaaa 23520 gtaaaagaat gtaaatcaaa aatacctgaa aacccatatc tatgattttg ctatttagtg 23580 agaaattcct cattgcactg aaaatcctta aaactagtac cccacttcat actatactac 23640 ggggttagac cacaattagt tgtttatcct ttgcacaccg caaacctata aattttcttt 23700 ttgtcaattc cacatattct acaaggagga ttgacttttt agttcactga ttattgctct 23760 ttcaacaatt tatacgcggt agttttactg ctcttcggct cgtataattt ttttacacaa 23820 cacttttatc gattttttaa gccgaatttc tacatttaat attttatcat ttttttctgc 23880 tcattaatat ttaccgtatc ttttcgaaaa cccattgctt tggatgtgtg tgtgtgtctc 23940 tctctctacg ttcctcaatt tgactgcatt actttaatat acttacaacc tgaattctgt 24000 tcggttggta attcctgcaa tcgttatttg tctttgtcaa cttcggattt tttattttta 24060 catataacag tagttgcatt gacttcgctg cacaattcct tacactgagt tggcattcct 24120 tgcatctgta aaccactttt tcattaccca ctcccatttt tgacttcagt aaacaattat 24180 tctactacta cttgccacta ttccaaactt atctgtttcc cgttttgggt ttaaatttgg 24240 gtataacggt cttttttata cataacttct gaagcaattc gaaatttgtt cctcaacaaa 24300 catggaaaat attttggatc cttctgtggt caattcacat atactagaaa atggctcaag 24360 gcgatcttct atcaatccaa ttcttgatag tgaattgcgt gataaaacat ttgaaaaggc 24420 tcatcgtcgc tctttgactt tactttcaag ttttacctcg tctatgcttg aacttcctaa 24480 caacggaaaa gaagaaaatc acagaaggcc atctgttgcg cgtagctcaa gtgatagatc 24540 caaggcgagc gccaaagagg acttattttc agaagctttc agaatggctg aacagcctcc 24600 agccgaggcc cttactattt ctacccctgt tgacccaatc aatattgatg aattagatcg 24660 tgcttatgcc gtaagtccaa gcgatactag taatctacta catcctccta cttcttcctc 24720 ttccattcct ataccaatta agaatgctgg tcattcaaac ctcgatcatc ctatccgacc 24780 tagtctgcaa agtagtatta gctcaaatag gataataaag tctcccggta ttaaggaaga 24840 cgattatatg cacagaggac gttctatttc gtcgccaatg attgatgttg aacacataaa 24900 ttcaacagca gttccaagca aaactaaaaa tttgccagaa aagcccaagc gttctcacaa 24960 actaagaaat tctataacat ttgctaaaat tgaagatcat cctgagagga aatctcaatt 25020 aagacgactg agtagttcgt taaagtgttt tgacccagaa tatgattata acgatccttc 25080 tctaagcatt cgtcgtgata gttcaactta ttacttttct aatgttaatg aaacttatga 25140 tgaggaggac tcggatttag attctgagac ttcaactgta aattgggtac aatctgttct 25200 gaatctccca tccttacttt ctgatgattt aatggctaac ccaaaaaaca aagaacgttt 25260 tgaatggcaa tatatgttga cttcagttct gactggtgat atagtccgat ctgaaaaatt 25320 acggctaaga aagattgctt cttctcgaga agggcgaaat agtgattatt ctgataattt 25380 gtggatggaa atatggtgtt ggcttactca tcgttccgtt gattcttata gagaaaattt 25440 aaaacatctt cgtacgggta tggttgatgt gctactggcc attatgaatt ttcattggga 25500 tgagagcaac gaattaaccc ctattgttgc tgtcgataac atgctgcaaa aacttgataa 25560 atatgaacgt ttatatcctt cacgtcgttc tatccttcag gaacattcat tatatgcttc 25620 agaatctttt cagcacaagt tggatgtctt gacggcttat tctaatgtca ctcatgcgct 25680 agaaattcaa gttaacatta ttcgctcgtg ggttggtaat gaggaaatgg acattaccaa 25740 aaatactaca aattctatta ataacgtttc tcaaatttca aacggaccat ttgtggagcg 25800 cttttataga gaaaccggtt tgattcgagc ttttgagcaa agaatcatga ctaatatgaa 25860 tagcgtatta agcaaagttt gtaatacgat tgttacatat gcggatgatt taaaaagtta 25920 tggcttgccg cttattgctg atgattacat gcgtcttctt tcttttccgt ttaggttaat 25980 caaagagttc ctaaatcttc gcttatcatg tgcagaaaat attacctcaa tttctttatt 26040 tacgattgac tctttactag atgaccttcg gaacactatg aaagttgccg tccatatcat 26100 tcaacaacac actgttctaa tcaaaccttt tcgtgatgat agcaaatttg ttgatgaaaa 26160 ccagtcctta aacaatattt tagttgcctc attgaaattt tacttcaatt tattacatcg 26220 taaggttcgc aatggctgtg ccttgctgca tttcaaagaa accgaaattt tagaaggaga 26280 atgggatttt ctgctcgctg tttgtcccca catcgaacac ggattccaaa ttatgtctaa 26340 aagtctttct tcgctggttg gtgaaatatt gaccaatatc aataggtatc taaaagatc 26399 //