Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: abnormal organelle localization (FYPO:0006329)
Definition Parents
A cell phenotype observed in the vegetative growth phase of the life cycle in which organelle localization, i.e. any process in which an organelle is transported to, and/or maintained in, a specific location, is abnormal.
External links: BioPortal
Single locus phenotype annotations for FYPO:0006329 and its descendants
Cell
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Filters:
+ abnormal attachment of mitotic spindle microtubules to kinetochore
cnp20-ts1(unknown) ,   ndc80-L405P(aa) ,   ndc80Δ371-476(aa) ,   ndc80Δ400-476(aa) ,   nup132Δ ,   pdk1Δ
+ abnormal centromere clustering at nuclear periphery
crm1-809(E430K aa) ,   csi1-2LP(L199P,L209P aa) ,   csi1Δ(2-29)(aa) ,   mis6-302(G135E aa) ,   mis6Δ ,   msd1Δ ,   sad1.1(A323V aa) ,   mto1Δ
+ abnormal centromere localization
ase1Δ ,   ned1+[Overexpression]
+ abnormal endoplasmic reticulum localization
cdc12-112(F1355S aa) ,   cdc15-140(unknown) ,   cdc4-8(G107S aa) ,   scs22Δ ,   scs2Δ
+ abnormal interphase mitotic telomere clustering during vegetative growth
rdp1-D903A(aa)
+ abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture
klp5Δ
+ abnormal lateral attachment of mitotic spindle microtubules to kinetochore
klp5Δ
+ abnormal mitochondrion inheritance during vegetative growth
emr1Δ
+ abnormal mitotic chromosome congression
cam1-E14(E69V,E106V aa) ,   klp5-Q582P(aa) ,   mad1-KAKA(K24A,K25A aa) ,   alp1-1315(unknown) ,   alp1-t1(unknown) ,   csi1Δ ,   dam1-A8-ts(H126R,E149G aa) ,   mad1-KAKA(K24A,K25A aa)
+ abnormal mitotic chromosome movement towards spindle pole
klp5Δ ,   klp6Δ
+ abnormal mitotic metaphase chromosome recapture
dis2Δ
+ abnormal mitotic sister chromatid biorientation
cid12Δ ,   spc7-23(T3887G,G4079T nt) ,   spc7-C(unknown)[Overexpression] ,   alp5-1134(S402N aa) ,   bub1-ΔGLEBS(264-299 Δaa) ,   bub3Δ
+ abnormal nucleus positioning during vegetative growth
crm1+[Overexpression] ,   hsp90-G84C(aa) ,   ned1+[Overexpression] ,   swo1-21(L654R aa)
+ abnormal telomere tethering at nuclear periphery during vegetative growth
lem2Δ ,   man1Δ
+ abnormal telomere-nuclear envelope distance during vegetative growth
lem2ΔC(567-669 Δaa)
+ abolished kinetochore sliding during chromosome recapture
dam1Δ
+ abolished mitochondrion inheritance during vegetative growth
mmb1Δ ,   dnm1Δ ,   mmb1Δ
+ abolished spindle pole body-led chromosome movement during mitotic interphase
mto1Δ
+ asymmetric mitochondrial aggregation
msp1Δ ,   nda3-KM311(G93E aa) ,   yta12Δ ,   nda3-KM311(G93E aa)
+ asymmetric mitochondrial aggregation at old end
ban5-4(unknown)
+ decreased centromere clustering at nuclear periphery during mitotic interphase
cnp3-T28E(aa) ,   clp1-C286S(aa) ,   csi1Δ ,   nsk1Δ ,   csi1Δ ,   lem2Δ ,   lem2ΔN(1-316 Δaa) ,   nup132Δ ,   pli1Δ ,   pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)[Overexpression] ,   sad1.2(T3S,S52P aa)
csi1Δ affecting cnp1
pli1Δ affecting cnp1
slx8Δ affecting cnp1
+ decreased endoplasmic reticulum-plasma membrane tethering
fhn1Δ ,   orb6-as1(M170G aa) ,   pil1-Nter(267-351 Δaa) ,   pil1Δ ,   pps1Δ ,   scs2-3KA(K36A,K38A,K43A aa) ,   scs2Δ ,   sec8-1(Q977*) ,   sle1Δ ,   scs2-3KA(K36A,K38A,K43A aa) ,   scs2-T39A,T40A(aa) ,   scs22-3KA(K36A,K38A,K43A aa) ,   scs22-3KA(K36A,K38A,K43A aa)[Overexpression] ,   scs2Δ
+ decreased interkinetochore distance before mitotic anaphase
klp6Δ
+ decreased kinetochore microtubule depolymerization during mitotic metaphase chromosome recapture
klp2Δ
+ decreased rate of kinetochore sliding during chromosome recapture
klp5Δ
+ decreased rate of mitotic metaphase chromosome recapture
klp5Δ ,   klp6Δ
+ decreased spindle pole body-led chromosome movement during mitotic interphase
atb2-983(V260I aa) ,   mto1-9A1(DNLRKEVFG259AAAAAAAAA aa) ,   mto1-9A2(GLKLKCYFL267AAAAAAAAA aa) ,   mto1Δ ,   tip1Δ
+ decreased telomere tethering at nuclear periphery during vegetative growth
pku80Δ
+ decreased telomere-nuclear envelope distance during mitotic G2 phase
rap1-5A(S213A,T378A,S422A,S456A,S513A aa) ,   rap1-S513A(aa)
+ decreased telomere-nuclear envelope distance during mitotic M phase
rap1-5A(S213A,T378A,S422A,S456A,S513A aa)
+ delayed onset of mitotic sister chromatid biorientation
klp5Δ
+ incomplete mitotic metaphase chromosome recapture
klp5Δ ,   klp6Δ
+ increased centromere clustering at nuclear periphery during mitosis
cut14-AID[Knockdown]
+ increased interkinetochore distance before mitotic anaphase
dis1-(unknown) ,   mis6-302(G135E aa) ,   nsk1Δ
+ increased mitochondrial-associated microtubule fraction during mitotic interphase
dnm1Δ
+ increased number of unattached kinetochores
dhc1Δ ,   cls1-28(L797P aa) ,   nda3-KM311(G93E aa) ,   wee1Δ
+ increased rate of kinetochore sliding during chromosome recapture
klp6Δ
+ increased telomere-nuclear envelope distance during mitosis
bqt4Δ
+ increased telomere-nuclear envelope distance during mitotic G2 phase
bqt4-3E-A(K83E,R94E,R97E aa) ,   bqt4-3E-B(K83E,K106E,R107E aa) ,   bqt4-F46A(aa) ,   bqt4-F61A(aa) ,   bqt4Δ ,   orb5-19(unknown) ,   rap1-5D(S213D,T378D,S422D,S456D,S513D aa) ,   rap1-5E(S213E,T378E,S422E,S456E,S513E aa) ,   rap1-7A(S317A,S329A,S484A,S487A,S496A,S497A,S538A aa) ,   rap1-D499A,E500A(aa) ,   rap1-F503R(aa) ,   rap1-S496A(aa) ,   rap1-S513E(aa) ,   rap1Δ ,   bqt4-F46A(aa) ,   bqt4Δ
+ increased variability of angle of spindle pole body-led chromosome movement during mitotic interphase
orb6-25(unknown)
+ merotelic kinetochore attachment during mitosis
ark1-as3(L166A,S229A,Q28R,Q176R aa)
+ meroterically attached lagging mitotic chromosomes
clr4Δ ,   csm1Δ ,   cdc13-117(C379Y aa) ,   cdc13-M7(E255G aa) ,   hrk1-pim(K8A,T9A,Y10A,G11A aa) ,   pds5-him(P84A,D85A,P87A aa) ,   rad21-K1(unknown) ,   bir1-8A(S202A,S229A,S244A,S278A,S294A,T393A,T831A,T908A aa)
+ mislocalized nucleus during vegetative growth
dnm1Δ ,   mmb1Δ ,   nda2-KM52(unknown) ,   pik3Δ ,   rpn11Δ ,   sds23Δ ,   tea2Δ ,   amo1Δ ,   ben1-(unknown) ,   gtb1+[Overexpression] ,   par1Δ ,   pfd1Δ ,   pfd2Δ ,   pfd3Δ ,   pfd4Δ ,   pfd5Δ ,   pfd6Δ
+ mitochondrial aggregation
alp11-924(W119*) ,   emr1Δ ,   mmb1Δ ,   msp1+[Overexpression] ,   nuc2-663(G504D aa) ,   yta4(EQ)(E192Q aa)[Overexpression] ,   msp1+[Overexpression]
+ mitochondrial aggregation during cellular response to reactive oxygen species
pka1Δ
+ monoseptate vegetative cell with binucleate and anucleate compartments
alp1-1315(unknown) ,   alp11-924(W119*) ,   clp1+[Overexpression] ,   cut20-100(unknown) ,   cut23-194(unknown) ,   cut9-665(A535T aa) ,   cut9-T98(unknown) ,   dad5+[Overexpression] ,   mde4Δ ,   mlo3+[Overexpression] ,   rpa2-G1143D(aa) ,   scn1-17(C35T nt) ,   scn2-7(C35T nt) ,   SPAC11D3.06+[Overexpression] ,   SPBC3H7.05c+[Overexpression] ,   toe3+[Overexpression] ,   tsm1-512(unknown) ,   alp12-1828(T1566C nt) ,   alp2-996(G1067A nt) ,   cdt1Δ ,   cut2-364(R262*) ,   int6Δ ,   lem2Δ ,   mal3+[Overexpression] ,   mcl1-1(W109*) ,   mis11-453(D307N aa) ,   mts2-1(unknown) ,   pol1-D984N(aa) ,   pol1-ts11(T840I aa) ,   pol1-ts13(470-472 Δaa) ,   pol1Δ ,   prp2-2(T259I aa) ,   prp2-C387Y(aa) ,   rfc3Δ ,   spp2-8(unknown) ,   vps4Δ
+ nucleus mislocalized towards cell equator during mitotic telophase
mto1-427(R1056A,E1059A,E1061A aa) ,   myp2Δ
+ nucleus mislocalized towards cell tip during mitotic interphase
ase1Δ ,   imp1Δ ,   int6Δ ,   kin1+[Knockdown] ,   klp5Δ ,   mal3+[Overexpression] ,   mto1Δ ,   mto2Δ ,   nda3-KM311(G93E aa) ,   alp12-1828(T1566C nt) ,   alp2-996(G1067A nt) ,   imp1Δ ,   mal3Δ ,   mto1Δ ,   rsp1+[Overexpression] ,   rsp1-1(P41L aa) ,   rsp1Δ
+ nucleus mislocalized towards cell tip during mitotic telophase
mto1(1-1085)(1086-1115 Δaa) ,   mto1Δ
+ septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to hydroxyurea
rad26.a14(C510CNPLIVC)
+ septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to salt stress
plb1Δ
+ symmetric mitochondrial aggregation
mmd1-1(E66L aa) ,   mmd1Δ ,   ban5-4(unknown) ,   nda3-KM311(G93E aa)
+ syntelic kinetochore attachment during mitosis
ndc80-21(T307A,E379G,L405P aa)
+ telophase nuclear clustering
byr4+[Overexpression] ,   byr4-7A(S248A,S326A,T412A,T429A,S499A,T502A,S533A aa) ,   clp1Δ ,   cps1-191(unknown) ,   dma1-GFP(Dam1-SPB-tethered via sid4) ,   mal3Δ ,   ppc89-2(R542G,D582G,E659G,H677P,L683S aa) ,   ppc89-3(S634P,V654A,C676R aa) ,   sid2-250(E314K aa) ,   skb15+[Overexpression]
+ uncentered mitotic chromosome congression
klp6Δ
Multi-locus phenotype annotations for FYPO:0006329 and its descendants
Cell
Show details ...
Filters:
+ abnormal attachment of mitotic spindle microtubules to kinetochore
gtb1-93(P302L aa) mad2Δ
+ abnormal centromere clustering at nuclear periphery
nda3-KM311(G93E aa) pds5Δ ,   dam1Δ mto1Δ
+ abnormal endoplasmic reticulum localization
for3Δ myo51Δ myo52Δ scs22Δ scs2Δ ,   for3Δ scs22Δ scs2Δ ,   scs22Δ scs2Δ
+ abnormal kinetochore microtubule polymerization during mitotic metaphase chromosome recapture
klp5Δ klp6Δ
+ abnormal lateral attachment of mitotic spindle microtubules to kinetochore
alp14Δ klp5Δ ,   dis1Δ klp5Δ
+ abnormal mitotic chromosome congression
bub3Δ sgo2Δ
+ abnormal mitotic sister chromatid biorientation
dam1-A8-ts(H126R,E149G aa) klp6Δ
+ abnormal telomere-nuclear envelope distance during vegetative growth
bqt4Δ fft3Δ
+ abolished mitotic metaphase chromosome recapture
dam1Δ mto1Δ ,   klp5Δ mto1Δ
+ abolished nuclear displacement from cell division site after abolished mitotic sister chromatid separation
cdc12-112(F1355S aa) cut7-22(P1021S aa) ,   cdc7-24(unknown) cut7-22(P1021S aa) ,   cut7-22(P1021S aa) myo2-E1(G345R aa) myo51Δ ,   cut7-22(P1021S aa) rng3-65(G688E aa)
+ decreased centromere clustering at nuclear periphery during mitotic interphase
csi1Δ lem2Δ ,   bqt4Δ csi1Δ ,   csi1Δ lem2-K7R(K50R,K64R,K72R,K83R,K92R,K121R,K150R aa) ,   csi1Δ lem2-K7R(K50R,K64R,K72R,K83R,K92R,K121R,K150R aa) nup132Δ ,   csi1Δ nup132Δ ,   csi1Δ nup132Δ pli1Δ ,   csi1Δ nup132Δ pmt3+[Overexpression] ,   csi1Δ nup132Δ pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)[Overexpression] ,   csi1Δ nup132Δ slx8Δ ,   csi1Δ nup132Δ ufd1ΔCt(213-342 Δaa) ,   csi1Δ nup132Δ ulp1+[Overexpression] ,   csi1Δ pli1Δ ,   csi1Δ pmt3+[Overexpression] ,   csi1Δ pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)[Overexpression] ,   csi1Δ slx8Δ ,   csi1Δ ufd1ΔCt(213-342 Δaa) ,   csi1Δ ulp1+[Overexpression] ,   lem2-K7R(K50R,K64R,K72R,K83R,K92R,K121R,K150R aa) nup132Δ ,   nup132Δ pli1Δ ,   nup132Δ pmt3+[Overexpression] ,   nup132Δ pmt3-KallR(K14R,K30R,K39R,K51R,K53R,K54R,K60R,K63R,K71R aa)[Overexpression] ,   nup132Δ slx8Δ ,   nup132Δ ufd1ΔCt(213-342 Δaa) ,   nup132Δ ulp1+[Overexpression]
csi1Δ slx8Δ affecting cnp1
pli1Δ slx8Δ affecting cnp1
+ decreased endoplasmic reticulum-plasma membrane tethering
scs2+ scs22+ ,   scs2-PM(scs2+KKKKKKSKTKCVIM) scs22Δ scs2Δ
+ decreased rate of kinetochore sliding during chromosome recapture
dhc1Δ klp2Δ ,   klp5Δ klp6Δ
+ decreased rate of mitotic metaphase chromosome recapture
klp5Δ klp6Δ ,   klp2Δ nda3-KM311(G93E aa)
+ delayed onset of mitotic sister chromatid biorientation
klp5Δ klp6Δ
+ incomplete mitotic metaphase chromosome recapture
klp5Δ klp6Δ
+ increased number of unattached kinetochores
dhc1Δ nda3-KM311(G93E aa) ,   klp2Δ nda3-KM311(G93E aa) ,   nda3-KM311(G93E aa) pkl1Δ
+ increased spindle pole body-led chromosome movement during mitotic interphase
cut1+ cut1-C(1245-1828)(1-1244 Δaa)[Overexpression]
+ increased telomere-nuclear envelope distance during mitosis
bqt4Δ rap1Δ ,   pku80Δ rap1Δ
+ merotelic kinetochore attachment during mitosis
ark1-as3(L166A,S229A,Q28R,Q176R aa) swi6Δ
+ meroterically attached lagging mitotic chromosomes
bir1-8D(S202D,S229D,S244D,S278D,S294D,T393D,T831D,T908D aa) cdc13-M7(E255G aa) ,   hrk1-KD-CD(hrk1-K184R-CD) pds5-him(P84A,D85A,P87A aa)
+ mislocalized nucleus during vegetative growth
igo1Δ sds23Δ
+ mitochondrial aggregation
dnm1Δ tea2Δ
+ mitotic spindle collapse during anaphase B elongation with progressive spindle pole congression
ase1Δ rad21-K1(unknown)
+ monoseptate vegetative cell with binucleate and anucleate compartments
mal3Δ moe1Δ ,   srw1Δ wee1-50(G850E aa) ,   cdc6-ts3(R1064Q aa) rad26.a14(C510CNPLIVC) ,   cut14-208(S861P aa) nda3-KM311(G93E aa) ,   lem2Δ vps4Δ
+ nucleus mislocalized towards cell equator during mitotic telophase
myo2-E1(G345R aa) myp2Δ
+ nucleus mislocalized towards cell tip during mitotic interphase
kin1-K154R(aa)[Overexpression] tea4Δ ,   par1Δ tea4Δ
+ nucleus mislocalized towards cell tip during mitotic telophase
cut15+[Overexpression] cut15-85(G419S,G450S aa) imp1Δ
+ ribosome mislocalized to nucleoplasm
cmp7Δ pcp1-15(I172T,K543E,I624T,E732G,A1022V,I1153V,H1163R aa)
+ septation following abnormal chromosome segregation, with binucleate and anucleate compartment formation during cellular response to hydroxyurea
cdc17-K42(E298K aa) cdc2-3w(C67Y aa) ,   cdc2-3w(C67Y aa) cdc20-M10(unknown) ,   cdc2-3w(C67Y aa) cdc22-M45(unknown)
+ symmetric mitochondrial aggregation
ban5-4(unknown) mmd1-1(E66L aa) ,   ban5-4(unknown) cdc10-129(T429A aa) ,   ban5-4(unknown) cdc2-33(A177T aa) ,   ban5-4(unknown) cdc20-M10(unknown) ,   ban5-4(unknown) cdc7-24(unknown)
+ telophase nuclear clustering
byr4-7A(S248A,S326A,T412A,T429A,S499A,T502A,S533A aa) plo1-24c(unknown)
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