Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: abnormal mitotic spindle midzone assembly (FYPO:0003304)
Definition Parents
A microtubule cytoskeleton organization phenotype observed in the vegetative growth phase of the life cycle in which formation of the mitotic spindle midzone, the area in the center of the mitotic spindle where the spindle microtubules from opposite poles overlap, is abnormal.
External links: BioPortal
Single locus phenotype annotations for FYPO:0003304 and its descendants
Cell
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+ abnormal mitotic spindle midzone assembly
kis1-1(R65C aa)
+ monopolar mitotic spindle
alp14-1270(unknown) ,   alp16+[Overexpression] ,   alp4-1891(unknown) ,   alp7-5A-a(S50A,S51A,T100A,T116A,T131A aa) ,   ani1+[Overexpression] ,   ark1Δ ,   big1+[Overexpression] ,   cdc31Δ ,   cut11-2(C525R aa) ,   cut12+[Knockdown] ,   cut12-2(unknown) ,   cut12Δ ,   cut7+[Overexpression] ,   cut7-24(V968A aa) ,   cut7-332(unknown) ,   cut7-446(I954T aa) ,   fin1+[Overexpression] ,   fin1Δ ,   klp2+[Overexpression] ,   kms2+[Knockdown] ,   mal3-Q89R(aa)[Overexpression] ,   mra1+[Overexpression] ,   mzt1+[Knockdown] ,   pcr1+[Overexpression] ,   pkl1+[Overexpression] ,   plo1-ts19(W316*) ,   plo1Δ ,   rsp1+[Overexpression] ,   ucp3+[Overexpression] ,   alp7+[Overexpression] ,   brr6+[Knockdown] ,   brr6-ds1(G145D aa) ,   brr6.ts8(C194G aa) ,   cls1-36(unknown) ,   csi2Δ ,   cut7-21(M394T aa) ,   cut7-446(I954T aa)[Knockdown] ,   fin1-ts1(G188E aa) ,   fin1Δ ,   hhp1Δ ,   mal3(1-241)(242-308 Δaa)[Overexpression] ,   mal3+[Overexpression] ,   mal3-Q89R(aa)[Overexpression] ,   moe1Δ ,   pcp1-AID(pcp1::pcp1-XTEN16-3×sAID:kanMX6)[Knockdown] ,   plo1-24c(unknown) ,   plo1-D181N(aa)[Overexpression] ,   plo1-D181R(aa)[Overexpression] ,   plo1-E193V(aa)[Overexpression] ,   plo1-K69Q(aa)[Overexpression] ,   plo1-K69R(aa)[Overexpression] ,   plo1-T197V(aa)[Overexpression] ,   plo1Δ ,   ppc89+[Knockdown] ,   wip1Δ ,   fin1Δ/fin1+
+ monopolar mitotic spindle nucleated from old spindle pole body
cut11-1(L521F aa) ,   cut12-1(R536*) ,   pcp1-15(I172T,K543E,I624T,E732G,A1022V,I1153V,H1163R aa) ,   pcp1-18(L254S,L717P aa)
+ separate mitotic half spindles present
ani1+[Overexpression] ,   dam1Δ ,   dis1Δ ,   klp2Δ ,   nop58+[Overexpression] ,   pcr1+[Overexpression] ,   spc7-23(T3887G,G4079T nt) ,   ucp3+[Overexpression] ,   mal3+[Overexpression]
+ transient monopolar mitotic spindle
alp7Δ ,   alp7Δ(307-312)(aa) ,   csi1-I463N,P464N(aa) ,   csi1Δ
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