Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: decreased chromatin silencing at centromere central core (FYPO:0003217)
Definition Parents
A cellular process phenotype observed in the vegetative growth phase of the life cycle in which the chromatin silencing at the central core of the centromeric regions is decreased.
External links: BioPortal
Single locus phenotype annotations for FYPO:0003217 and its descendants
Cell
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Filters:
+ decreased chromatin silencing at centromere central core
clr2Δ ,   cnp1-169(V52A aa) ,   cnp1-76(T74M aa) ,   cnp1-87(E92K aa) ,   cos1-17(V233A aa) ,   cos1-22(A574D aa) ,   cos1-38(G622E aa) ,   cos1-7(G242R aa) ,   cos1-86(Q765*) ,   dis3-54(P509L aa) ,   fft3Δ ,   fta2-292(F292L aa) ,   hst4Δ ,   mal2-1(E277K aa) ,   mis6-302(G135E aa) ,   sim3-143(G81E aa) ,   sim3-205(E207K aa) ,   mis15-68(W113R aa) ,   mis6-302(G135E aa)[Knockdown] ,   arp8Δ ,   clr1-5(unknown) ,   clr3-735(D232N aa) ,   clr3Δ ,   cnp1-1(L87Q aa) ,   dpb3Δ ,   dpb4Δ ,   hrp1Δ ,   iec1Δ ,   ies2Δ ,   ies6Δ ,   ino80-11(D1531V aa) ,   mcl1-101(P493S,L763F,A767V aa) ,   mcm2-2a(Y80A,Y89A aa) ,   pli1-C321S(aa) ,   pli1Δ ,   pob3Δ ,   pst1-1(W1305*) ,   swi7-1(G1116E aa) ,   swi7-H4(unknown)
Genetic interactions where FYPO:0003217 is the double allele phenotype
Source: Interactions curated by BioGRID and PomBase
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Filters: Throughput Interaction Type
Gene Product Interacting gene Interacting product Interaction type
+ mcm2 MCM complex subunit Mcm2 rescued by dpb4 DNA polymerase epsilon subunit Dpb4 Phenotypic Suppression
Genetic interactions where FYPO:0003217 is the single mutant phenotype
Source: Interactions curated by BioGRID and PomBase
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Filters: Throughput Interaction Type
Gene Product Interacting gene Interacting product Interaction type
+ mcm2 MCM complex subunit Mcm2 rescued by dpb4 DNA polymerase epsilon subunit Dpb4 Phenotypic Suppression
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