PomBase - Ontology term - FYPO:0002336 - normal chromatin silencing at silent mating-type cassette

Ontology term: normal chromatin silencing at silent mating-type cassette (FYPO:0002336)

Definition	Parents
A transcription regulation phenotype observed in the vegetative growth phase of the life cycle in which chromatin silencing at the silent mating-type cassettes is normal (i.e. indistinguishable from wild type). Chromatin silencing is the observed effect of processes that repress transcription in a region of the genome that is normally assembled into heterochromatin.	is_a normal chromatin silencing

External links:

Single locus phenotype annotations for FYPO:0002336 and its descendants

Cell

Filters:

+	normal chromatin silencing at silent mating-type cassette
	ago1Δ , atf1-10A/I(S2A,S4A,T77A,S140A,S152A,S172A,T204I,T216I,S226A,T249I aa)[Ectopic] , atf1-10A/I(S2A,S4A,T77A,S140A,S152A,S172A,T204I,T216I,S226A,T249I aa) , atf1-4A/I(T77A,S115A,T204I,T249I aa)[Ectopic] , atf1-4D/E(T77E,S115D,T204E,T249E aa)[Ectopic] , atf1-6A/I(T77A,S115A,T166A,S172A,T204I,T249I aa)[Ectopic] , atf1-6D/E(T77A,S115D,T166D,S172D,T204E,T249E aa)[Ectopic] , atf1Δ , bqt4Δ , cbp1Δ , ccq1-1-31(W32) , chp1Δ , chp2-CSD2A(K321A,K322A aa) , chp2-CSD3A(Q320A,K321A,K322A aa) , chp2-H5A(K271A,R272A,R273A,R274A,R276A aa) , clr3Δ , clr4Δ , clr6-1(G269D aa) , ctf1Δ , dcr1Δ , dri1Δ , epe1Δ , ers1Δ , eso1-W804G(aa) , hat1Δ , hht3-K9R(K10R aa) , hrk1Δ , hst4Δ , lem2Δ , man1Δ , mmi1Δ , not2Δ , not3Δ , pcr1Δ , pht1Δ , psc3-4T(unknown) , puf6Δ , rad21-K1(unknown) , rae1-167(unknown) , raf2Δ , rcd1Δ , rdp1Δ , res2Δ , rif1-S44N,1-398(S44N,I400) , rpb2-m203(N44Y aa) , rss1Δ , saf1Δ , saf5Δ , sde2Δ , sgf73Δ , smd3Δ , ssu72-1-86(aa) , stc1Δ , swd22-1-209(W210*) , swi2Δ , swi6-115(W269R aa) , tas3Δ , taz1-C215G(aa) , TerR-swi6-CD(TerR-swi6-CD(mating type localized))[Ectopic] , tls1Δ , wpl1Δ , xap5Δ

Multi-locus phenotype annotations for FYPO:0002336 and its descendants

Cell

Filters:

+	normal chromatin silencing at silent mating-type cassette
	ago1Δ sgf73Δ , atf1Δ cdc22-3(I665F aa) , atf1Δ tds1-13(G445R aa) , caf1Δ epe1-H297A(aa) , caf1Δ epe1Δ , cdc22-3(I665F aa) clr1-5(unknown) , cdc22-3(I665F aa) clr2-760(unknown) , cdc22-3(I665F aa) clr3-375(unknown) , cdc22-3(I665F aa) clr4-G486D(aa) , cdc22-3(I665F aa) pcr1Δ , cdc22-3(I665F aa) swi6-(unknown) , clr5Δ clr6-1(G269D aa) , epe1+[Overexpression] gcn5-E191Q(aa) , epe1+[Overexpression] ngg1Δ , epe1-H297A(aa) mot2Δ , epe1Δ mot2Δ , epe1Δ spt16-1(unknown)[Knockdown] , eso1Δ psm3-KKQQ(K105Q,K106Q aa) , eso1Δ psm3-KKQQ(K105Q,K106Q aa) wpl1Δ , pcr1Δ tds1-13(G445R aa) , pds5Δ psc3Δ rad21Δ rec11+[Overexpression] rec8+[Overexpression] , pds5Δ psm3-KKQQ(K105Q,K106Q aa) , psc3Δ rad21Δ rec11+[Overexpression] rec8+[Overexpression] , sty1-T97A(aa) wis1-DD(S469D,T473D aa)[Overexpression] , sty1Δ wis1-DD(S469D,T473D aa)[Overexpression] , swi6+ swi6+ , swi6+ swi6-115(W269R aa) , swi6+[Overexpression] swi7-1(G1116E aa) , swi6-(unknown) tds1-13(G445R aa) , lsd1-ao(K603A,K604A aa) lsd2-ao(K823A,K824A aa)

Genetic interactions where FYPO:0002336 is the double allele phenotype

Source: Interactions curated by BioGRID and PomBase

Filters:

Throughput

Interaction Type

	Gene	Product		Interacting gene	Interacting product	Interaction type
+	caf1	CCR4-Not complex CAF1 family ribonuclease subunit 7/8	rescued by	epe1	histone demethylase, Jmjc domain Epe1	Phenotypic Suppression
+	mot2	CCR4-Not complex ubiquitin-protein ligase E3 subunit 4	rescued by	epe1	histone demethylase, Jmjc domain Epe1	Phenotypic Suppression
+	wis1	MAP kinase kinase Wis1	rescued by	sty1	MAP kinase Sty1	Phenotypic Suppression