Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: abnormal RNA processing (FYPO:0001553)
Definition Parents
A cellular process phenotype observed in the vegetative growth phase of the life cycle in which RNA processing is abnormal. RNA processing is the conversion of one or more primary RNA transcripts into one or more mature RNA molecules.
External links: BioPortal
Single locus phenotype annotations for FYPO:0001553 and its descendants
Cell
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+ abnormal 5.8S rRNA 3'-end processing
eri1Δ
+ abnormal box C/D snoRNA 3'-end processing
snu32-+41(GTG295ACA nt) affecting snu3
snu32-+46(AA300TT nt) affecting snu3
snu32-+50(TGT303ACA nt) affecting snu3
snu32-+56(AA309TT nt) affecting snu3
+ abnormal mitochondrial RNA 3'-end processing
rpm1Δ ,   rpm2Δ
+ abnormal mRNA alternative polyadenylation
nc-tgp1-5seb1-bs(T543A,G549C,A554T,A560AT,T561A,C570G,G573A,C579G,T582A nt)[Knockdown] affecting tgp1
rpb1-N494D(aa) affecting nc-tgp1
seb1-G476S(aa) affecting ado1 , dbp2 , eap1 , esl1 , fil1 , gms1 , gpd1 , gst3 , hhp1 , pcl1 , SPBPB8B6.05c
+ abnormal mRNA cleavage and polyadenylation specificity factor complex assembly
seb1+[Knockdown]
+ abnormal regulatory lncRNA 3'-end processing
cbc1-1(unknown) affecting nc-pho1
mmi1Δ affecting nam1 , nc-pho1
red1Δ affecting nam1 , nc-pho1
rrp6Δ affecting nam1 , nc-pho1
+ abnormal RNA 3'-end processing during cellular response to endoplasmic reticulum stress
bip1-ΔTTAACTGGTG\C(2356-2366 Δnt) affecting bip1
bip1-G2365C(nt) affecting bip1
bip1-G2365T(nt) affecting bip1
ire1Δ affecting bip1
+ abnormal RNA 5'-end processing
hst4Δ affecting LTR_retrotransposon
+ abnormal snRNA 3'-end processing
mpn1-MUT(H109A,H199A aa)[Overexpression] affecting U6_snRNA
mpn1Δ affecting U6_snRNA
+ abnormal spliceosomal complex assembly
gem8+[Knockdown] ,   tdSMN(Ub-DHFRts-smn1)
+ abnormal tRNA methylation
trm401Δ ,   trm402Δ
+ abnormal tRNA processing
rmp1-KA18(Q12R,P57L,Y60H,V86A,L132S,I142T,Y149C,L161P,S167P,V192A,F210L aa)
+ abolished 18S rRNA acetylation
nat10-447(G285D aa)
+ abolished 7-methylguanosine cap hypermethylation
tgs1Δ
+ abolished snRNA 3'-end processing
snu2-M1(CTTCTTCT189TACTAGTG nt) affecting snu2
snu2-M2(GTTGACAG197TACTAGTA nt) affecting snu2
snu2-M3(ATTTGTGA205GACTAGTC nt) affecting snu2
+ abolished tRNA cytidine N4-acetylation
tan1Δ affecting seryl_tRNA
+ abolished tRNA cytosine 2'-O-methylation
trm7+[Knockdown] affecting SPATRNAPHE.01
trm732Δ affecting SPATRNAPHE.01
trm732Δ/trm732Δ affecting SPATRNAPHE.01
trm734Δ affecting SPATRNAPHE.01
+ abolished tRNA guanosine 2'-O-methylation
trm7+[Knockdown] affecting SPATRNAPHE.01
trm734Δ/trm734Δ affecting SPATRNAPHE.01
+ abolished tRNA guanosine 7-methylation
trm8Δ
+ abolished tRNA guanosine N2,N2-dimethylation
trm1-D201A(aa) ,   trm1Δ
+ abolished tRNA splicing
ptp4-(unknown)
+ abolished tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridine biosynthesis
elp3Δ
ctu1Δ affecting glutaminyl_tRNA , glutamyl_tRNA , lysyl_tRNA
ctu2Δ affecting glutaminyl_tRNA , glutamyl_tRNA , lysyl_tRNA
elp3Δ affecting glutaminyl_tRNA , glutamyl_tRNA , lysyl_tRNA
+ abolished tRNA wobble position uridine thiolation
ctu1-C142A,C145A(aa) ,   ctu1-K62A,D63A(aa) ,   ctu1-ts21(unknown) ,   ctu1Δ ,   elp3Δ
+ abolished tRNA-Asp C38 methylation
pmt1-C81A(aa)
qtr1Δ affecting aspartyl_tRNA
+ decreased mitochondrial tRNA 3'-end processing
rpc11-C102S(aa) ,   rpc11-D90G,R107C(aa)
+ decreased snRNA 3'-end processing
snu2-M4(CGCATGAAT213ATACTAGTC nt) affecting snu2
snu2-M5(TTGACAAC222GGACTAGT nt) affecting snu2
snu2-M6(ATTGGATGG230GACTAGTCC nt) affecting snu2
+ decreased tRNA 5'-leader removal
rrk1::ura4+[Null]/rrk1+
+ decreased tRNA guanosine 7-methylation
trm7+[Knockdown] affecting SPATRNAPHE.01
trm734Δ affecting SPATRNAPHE.01
+ decreased tRNA guanosine N2-methylation
trm7+[Knockdown] affecting SPATRNAPHE.01
trm734Δ affecting SPATRNAPHE.01
+ decreased tRNA wybutosine biosynthesis
trm7+[Knockdown]
trm732Δ affecting SPATRNAPHE.01
trm734Δ affecting SPATRNAPHE.01
+ formation of abnormal tRNA processing intermediates
mrp1-ND90(111-198 Δnt)
maf1Δ affecting imt06 , spl1 , SPATRNAALA.06 , SPATRNAARG.01 , SPATRNAARG.03 , SPATRNACYS.01 , SPATRNAILE.01 , SPATRNAMET.02 , SPATRNAPHE.01 , SPATRNATHR.03 , SPATRNATHR.04 , SPATRNATYR.01 , SPATRNAVAL.01 , SPBTRNAASN.01 , SPBTRNAASN.02 , SPBTRNAASN.04 , SPBTRNAGLN.02 , SPBTRNAGLY.04 , SPBTRNAGLY.09 , SPBTRNAHIS.01 , SPBTRNAMET.05 , SPBTRNAPRO.07 , SPBTRNATHR.06 , SPBTRNATRP.02 , SPBTRNATRP.03 , SPCTRNAALA.12 , SPCTRNAARG.10 , SPCTRNAASN.05 , SPCTRNAGLY.12 , SPCTRNAHIS.03 , SPCTRNAPHE.04 , SPCTRNATHR.10
pac1-A342T(aa) affecting seryl_tRNA
sla1Δ affecting leucyl_tRNA , lysyl_tRNA , valyl_tRNA
+ increased small RNA 3' adenylation
tri1Δ
+ increased tRNA guanosine 1-methylation
trm7+[Knockdown] affecting SPATRNAPHE.01
trm732Δ affecting SPATRNAPHE.01
trm734Δ affecting SPATRNAPHE.01
+ increased tRNA guanosine N2,N2-dimethylation
sla1Δ
+ increased tRNA-Asp C38 methylation
pmt1+[Overexpression]
trm402Δ affecting SPATRNAASP.01 , SPATRNAASP.02
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