Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: loss of viability at high temperature (FYPO:0001387)
Definition Parents
A cell population phenotype in which a smaller than normal proportion of cells in the population remains viable when cells are grown at a temperature higher than standard.
External links: BioPortal
Single locus phenotype annotations for FYPO:0001387 and its descendants
Population
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Filters:
+ loss of viability at high temperature
btn1Δ ,   cdc10-129(T429A aa) ,   cdc17-K42(E298K aa) ,   cdc18-K46(unknown) ,   cdc19-P1(P257L,T272I aa) ,   cdc20-M10(unknown) ,   cdc21-M68(unknown) ,   cdc23-M36(D232G,V265I aa) ,   cdc28-P8(unknown) ,   cnp20-9(S160C,T197S,L394W,A433D aa) ,   cnx1-mini(23-437 Δaa) ,   cnx1-miniTM(23-437,512-560 Δaa) ,   cnx1-smini(23-437,490-560 Δaa) ,   cnx1-ss14(Y183*) ,   cut11-6(T498I aa) ,   cut14-208(S861P aa) ,   cut14-L499P(aa) ,   cut14-Y1(L543S aa) ,   cut3-477(S1147P aa) ,   cut3-S647P(aa) ,   cut6-621(unknown) ,   cwh43-G753R(aa) ,   dam1Δ ,   drc1-1(unknown) ,   drc1-2(unknown) ,   drp1-654(M218I aa) ,   eso1-G799D(aa) ,   hsk1-89(L339P,E403K,L416P aa) ,   hsp90-G84C(aa) ,   kap104Δ ,   kap123Δ ,   krp1-F425S(aa) ,   mac1Δ ,   mal2-1(E277K aa) ,   mcm7-98(G1931A nt) ,   mis11-453(D307N aa) ,   mis12-537(G52E aa) ,   mis18-262+pocket(Y74A,Y90A,T105A,S107K,G117D aa) ,   mis18-262(G117D aa) ,   mis18-818+I31A(T49A,I31A aa) ,   mis18-818+Y114A(T49A,Y114A aa) ,   mis18-818(T49A aa) ,   mis6-302(G135E aa) ,   mrp1-Pt1-9(C357A,T360A nt) ,   mrp1-RR90(199-282 Δnt) ,   mts1-1(unknown) ,   mts10-1(unknown) ,   mts2-1(unknown) ,   mts3-1(unknown) ,   mts4-1(unknown) ,   mts5-1(unknown) ,   mts6-1(unknown) ,   mts7-1(unknown) ,   mts8-1(disruption) ,   mts9-1(unknown) ,   ndc80-21(T307A,E379G,L405P aa) ,   ndc80-NH12(F420S aa) ,   nuc1-632(unknown) ,   nuf2-1(unknown) ,   nuf2-2(unknown) ,   nuf2-3(unknown) ,   nuf2-4(unknown) ,   orc5-H19(V43A,C71R,Y177C,P191S,I352T aa) ,   orp1-4(unknown) ,   par1-35(unknown) ,   par1Δ ,   pct1-NΔ50(1-50 Δaa) ,   pfs2-11(unknown) ,   pim1-46(unknown) ,   pol1-ts11(T840I aa) ,   pol1-ts13(470-472 Δaa) ,   ppc1-537(T48I aa) ,   ppc1-88(M209T aa) ,   prp1-4(L616I,S779L aa) ,   prp2-C387Y(aa) ,   rad3-A2217V(aa) ,   rad4-A60P(aa)[Knockdown] ,   rae1-1(G219E aa) ,   rae1-167(unknown) ,   rfc1-44(S811SIRGTP) ,   rfc3-1(R216W aa) ,   rhn1Δ ,   rhp6-788(unknown) ,   rna14-11(R316Q aa) ,   rna14-A394E(aa) ,   rsv1Δ ,   sld3-10(E338G aa) ,   spt16-17(unknown) ,   spt16-18(unknown) ,   sty1Δ ,   swo1-21(L654R aa) ,   top2-191(unknown) ,   vgl1Δ ,   win1-1(unknown) ,   wis1Δ ,   cdc13-563(G282D aa) ,   cdc18-K46(unknown) ,   cdc20-P7(unknown) ,   cdc21-M68(unknown) ,   cdc27-P11(G57E aa) ,   cdc42-mCherrySW-2ritC(cdc42(1-134)-linker-mCherry-linker-cdc42(135-188)-2xritC) ,   cdc6-ts1(AP143VS aa) ,   cdc6-ts2(E271K aa) ,   cdc6-ts3(R1064Q aa) ,   cps8-188(G273D aa) ,   end4Δ ,   lsd1-ao(K603A,K604A aa) ,   mcm4-tstd(Ub-DHFRts-mcm4) ,   mis4-C-A(1-191,K873A,K877A aa) ,   mis4-C-B(1-191,K1420A,K1423A,K1427A aa) ,   mzt1-T27W(aa) ,   orc5-H37(L266P,P375L aa) ,   snf21-36(V404A,E461K,S566L,I571V aa) ,   spp1-14(unknown) ,   spp1-21(unknown) ,   spp1-4(unknown) ,   spp2-8(unknown) ,   spp2-9(unknown) ,   stn1-226(I226A,L227A,L229A aa)
Multi-locus phenotype annotations for FYPO:0001387 and its descendants
Population
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Filters:
+ loss of viability at high temperature
alp7-LA6(L380A,L387A,L391A,L405A,L418A,L419A aa) mad2Δ ,   bub1Δ mcl1+[Knockdown] ,   cdc17-K42(E298K aa) rad3-136(unknown) ,   cdc20-P7(unknown) cid1Δ ,   cdc25-22(C532Y aa) wee1-50(G850E aa) win1-1(unknown) ,   cdc27-P11(G57E aa) cid1-DADA(D101A,D103A aa) ,   cdc27-P11(G57E aa) cid11Δ ,   cdc27-P11(G57E aa) cid12Δ ,   cdc27-P11(G57E aa) cid1Δ ,   cdc6-121(unknown) cid1Δ ,   cdc6-ts1(AP143VS aa) cid1Δ ,   cdc6-ts2(E271K aa) cid1Δ ,   cig2Δ srw1Δ wee1-50(G850E aa) ,   cnp1+[Overexpression] pob3Δ ,   cnp1+[Overexpression] spt16-18(unknown) ,   cnp1+[Overexpression] spt6-1(856-919 Δaa) ,   ctf1Δ ppn1-1-593(594-710 Δaa) ,   ctf1Δ ppn1-1-639(640-710 Δaa) ,   ctf1Δ ppn1-451-710(1-450 Δaa) ,   gle1+[Overexpression] rae1-167(unknown) ,   hht1Δ hht2-S86A,S87A(S87A,S88A aa) hht3Δ ,   klp5(PP1mut)(V683A,F685A,V694A,F696A aa) ndc80-NH12(F420S aa) ,   klp6(PP1mut)(V674A,F676A aa) ndc80-NH12(F420S aa) ,   mex67+[Overexpression] rae1-167(unknown) ,   mik1Δ wee1-50(G850E aa) ,   mis18-262(G117D aa) pob3Δ ,   mis6-302(G135E aa) pob3Δ ,   mor2-786(A1673G nt) wee1Δ ,   par1Δ par2Δ ,   par1Δ wee1-50(G850E aa) ,   pin1Δ ppn1-1-593(594-710 Δaa) ,   pin1Δ ppn1-1-639(640-710 Δaa) ,   pin1Δ ppn1-451-710(1-450 Δaa) ,   ppn1-1-593(594-710 Δaa) rhn1Δ ,   ppn1-1-593(594-710 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-1-593(594-710 Δaa) rpb1-CTD-T4A(aa) ,   ppn1-1-593(594-710 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-1-593(594-710 Δaa) ssu72-C13S(aa) ,   ppn1-1-606(607-710 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-1-606(607-710 Δaa) rpb1-CTD-T4A(aa) ,   ppn1-1-606(607-710 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-1-639(640-710 Δaa) rhn1Δ ,   ppn1-1-639(640-710 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-1-639(640-710 Δaa) rpb1-CTD-T4A(aa) ,   ppn1-1-639(640-710 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-1-639(640-710 Δaa) ssu72-C13S(aa) ,   ppn1-331-639(1-330,640-710 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-331-710(1-330 Δaa) rhn1Δ ,   ppn1-331-710(1-330 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-331-710(1-330 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-331-710(1-330 Δaa) ssu72-C13S(aa) ,   ppn1-386-710(1-385 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-386-710(1-385 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-451-710(1-450 Δaa) rhn1Δ ,   ppn1-451-710(1-450 Δaa) rpb1-CTD-S2A(aa) ,   ppn1-451-710(1-450 Δaa) rpb1-CTD-T4A(aa) ,   ppn1-451-710(1-450 Δaa) rpb1-CTD-Y1F(aa) ,   ppn1-488-710(1-487 Δaa) rhn1Δ ,   ppn1-RYK-AAA(R586A,Y588A,K589A aa) rpb1-CTD-S2A(aa) ,   sds21ΔC(302-322 Δaa) ssu72-C13S(aa) ,   bub1Δ mcl1-1(W109*) ,   bub1Δ pfs2-11(unknown) ,   cdc1-7(unknown) cps8-185(unknown) ,   cdc13-563(G282D aa) cig2+[Knockdown] ,   cdc17-K42(E298K aa) chk1::ura4(chk1::ura4@(CU329672.1:1060123_1061101delins)) ,   cdc18-K46(unknown) chk1Δ ,   cdc20-M10(unknown) chk1Δ ,   cdc20-P7(unknown) cid12Δ ,   cdc21-M68(unknown) mus81Δ ,   cdc22-M45(unknown) cps8-185(unknown) ,   cdc25+[Overexpression] cps8-185(unknown) ,   cdc25-22(C532Y aa) cps8-185(unknown) ,   cdc25-22(C532Y aa) mcl1-1(W109*) ,   cdc27-P11(G57E aa) chk1Δ ,   cdc27-P11(G57E aa) chk1Δ cid1Δ ,   cdc27-P11(G57E aa) cid12Δ ,   cdc27-P11(G57E aa) cid1Δ ,   cdc27-P11(G57E aa) cid1Δ crb2Δ ,   cdc27-P11(G57E aa) crb2Δ ,   cdc27-P11(G57E aa) rad1Δ ,   cdc6-ts1(AP143VS aa) chk1Δ ,   cdc6-ts2(E271K aa) chk1Δ ,   cdc6-ts3(R1064Q aa) chk1Δ ,   cdc6-ts3(R1064Q aa) crb2Δ set1::Kan(disruption)[Null] ,   cdr2Δ set1::Kan(disruption)[Null] ,   cds1Δ mcm4-tstd(Ub-DHFRts-mcm4) mus81Δ ,   chk1Δ orc5-H19(V43A,C71R,Y177C,P191S,I352T aa) ,   cps8-185(unknown) nda2-KM52(unknown) ,   dma1Δ pol1-1546(unknown) ppb1Δ ,   exo1Δ stn1-226(I226A,L227A,L229A aa) ,   lsd1-ao(K603A,K604A aa) lsd2-ao(K823A,K824A aa) ,   mcl1-1(W109*) wee1-50(G850E aa) ,   orc5-H19(V43A,C71R,Y177C,P191S,I352T aa) rad1Δ ,   orc5-H19(V43A,C71R,Y177C,P191S,I352T aa) rad9Δ ,   pol1+[Overexpression] stn1-226(I226A,L227A,L229A aa)
Genetic interactions where FYPO:0001387 is the double allele phenotype
Source: Interactions curated by BioGRID and PomBase
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Filters: Throughput Interaction Type
Gene Product Interacting gene Interacting product Interaction type
+ lsd2 histone demethylase SWIRM2 synthetic growth defect with lsd1 histone demethylase SWIRM1 Synthetic Growth Defect
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