Last updated: 2025-03-13 429297 annotations 4738 curated publications
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Ontology term: normal catalytic activity (FYPO:0000660)
Definition Parents
A molecular function phenotype in which the observed rate and other catalytic properties of a specified catalytic activity are normal (i.e. indistinguishable from wild type).
External links: BioPortal
Single locus phenotype annotations for FYPO:0000660 and its descendants
Cell
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Filters:
+ normal alpha,alpha-trehalase activity increase during cellular response to oxidative stress
atf1Δ
+ normal cytochrome-c oxidase activity
urfa-anaR-6(L113*)
+ normal histone methyltransferase activity (H3-K9 specific) activity
clr4-KMT(1-191 Δaa) affecting hht1 (Ubiq(K14))
clr4-W31G(aa) affecting activity of clr4
clr4-W41G(aa) affecting activity of clr4
+ normal catalytic activity
trz1-ΔN38(1-38 Δaa) affecting trz1
+ normal 1,3-beta-D-glucan synthase activity
pck1+[Overexpression] ,   pck1::ura4+ ,   pck2::LEU2(disruption)
+ normal 1,3-beta-D-glucan synthase activity during vegetative growth
bgs2+[Overexpression] ,   bgs2::his3(disruption)[Null] ,   pbr1-6(W760S aa) ,   pbr1-8(E700V aa)
+ normal 3'-5' RNA helicase activity
prp16-F528S(aa) affecting activity of prp16
+ normal 5' deoxyribonuclease (pyrimidine dimer) activity
rad13-A(unknown)
+ normal 5' deoxyribonuclease (pyrimidine dimer) activity during cellular response to UV
rad9::ura4+
+ normal 5'-deoxyribose-5-phosphate lyase activity
pol4-D355A,D357A(aa)
+ normal 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity
myh1-F444A(aa)
+ normal acid phosphatase activity
pho4-4(unknown) ,   pho4Δ ,   sec5-S50A(aa)
duf89-D252A(aa) affecting activity of pho1
duf8901Δ affecting activity of pho1
gde1Δ affecting activity of pho1
pho7-K282A(aa) affecting activity of pho1
pho7-N299A(aa) affecting activity of pho1
plt1Δ affecting activity of pho1
rad24-ΔC(1-240 Δaa) affecting activity of pho1
rpb1-(CTD-13repeats)(CTD-∆(r14-r29)) affecting activity of pho1
rpb1-(CTD-16repeats)(CTD-∆(r17-r29)) affecting activity of pho1
rpb1-(CTD-18repeats)(CTD-∆(r19-r29)) affecting activity of pho1
rpb1-(CTD-20repeats)(CTD-∆(r21-r29)) affecting activity of pho1
rpb1-(CTD-26repeats)(CTD-∆(r27-r29)) affecting activity of pho1
rpb1-CTD-P3A(r2-r29-2)(aa) affecting activity of pho1
siw14Δ affecting activity of pho1
spx2Δ affecting activity of pho1
vtc2Δ affecting activity of pho1
vtc4Δ affecting activity of pho1
+ normal adenylyl cyclase activity
git2-210(unknown) ,   git2-7(unknown)
+ normal alkaline phosphatase activity
zhf1Δ
+ normal alkaline phosphatase activity during stress response to zinc ion
cis4Δ ,   zrg17Δ
+ normal alpha,alpha-trehalase activity
ntp1-S41A(aa)
+ normal alpha,alpha-trehalase activity during cellular response to nutrient
pka1Δ
+ normal alpha,alpha-trehalase activity increase during cellular response to heat stress
ntp1-I104A(aa) ,   pka1Δ ,   sck1Δ ,   sty1Δ ,   wis1Δ
+ normal alpha,alpha-trehalase activity increase during cellular response to salt stress
atf1Δ ,   ntp1-I104A(aa) ,   pap1Δ ,   pka1Δ ,   tps1Δ
+ normal ATPase activity
mdn1-F1093L(aa)
asp1(1-385)(386-920 Δaa)[Overexpression] affecting activity of asp1
pct1-NΔ40(1-40 Δaa) affecting pct1
pfh1-L430V(aa) affecting activity of pfh1
prp16-F528S(aa) affecting activity of prp16
rlc1-DD(S35D,S36D aa) affecting activity of myo2
rlc1-SA(S35A,S36A aa) affecting activity of myo2
+ normal diphosphoinositol-pentakisphosphate kinase activity
asp1-H807A(aa) affecting activity of asp1
+ normal DNA topoisomerase II activity
nuc1-632(unknown) ,   top2Δ(1-53)(1-54 Δaa) ,   top2Δ(2-74)(2-75 Δaa) ,   top2Δ-Sma(1312-1485 Δaa)
top2-2A(S1363A,S1364A aa) affecting activity of top2
top2Δ(1-74)(1-75 Δaa) affecting activity of top2
top2Δ(1-74)-Δ-Xba(1-75,1221-1485 Δaa) affecting activity of top2
top2Δ-Sma(1312-1485 Δaa) affecting activity of top2
+ normal DNA-1,N6-ethenoadenine N-glycosylase activity
mag1-F158S,S159G(aa)
+ normal DNA-7-methylguanine glycosylase activity
mag1-F158S,S159G(aa) ,   mag1-H64S(aa)
+ normal DNA-directed DNA polymerase activity
cdc27-D6M(242-351 Δaa)
+ normal DNA/DNA annealing activity
pfh1-KA(K338A aa) affecting activity of pfh1
pfh1-L430A(aa) affecting activity of pfh1
pfh1-L430P(aa) affecting activity of pfh1
+ normal farnesyltranstransferase activity
fps1-R104Q(aa)
+ normal fatty acid synthase activity
fas2-H201(I1276T aa) ,   fas2-H265(E4Y aa) ,   fas2-H518(I600N aa)
+ normal glucan endo-1,3-beta-glucanase activity
sep1-1(unknown)
+ normal glucosyltransferase activity
cwg1-1(unknown) ,   cwg2-1(A202T aa)
+ normal glutamate dehydrogenase (NAD+) activity
agg1-32(unknown) ,   gdh1Δ
+ normal glutamate dehydrogenase (NADP+) activity
gdh2Δ ,   gln1-1(unknown)
+ normal glutamate synthase (NADH) activity
gln1-1(unknown)
+ normal glutamate-ammonia ligase activity
agg1-32(unknown)
+ normal glutathione disulfide oxidoreductase activity
pap1Δ
+ normal glutathione gamma-glutamylcysteinyltransferase activity
pcs2-C148A(aa) ,   pcs2-C173A(aa) ,   pcs2-C186A(aa) ,   pcs2-C398A,C399A(aa) ,   pcs2-E375A(aa)
+ normal glycerol dehydrogenase activity
dak2Δ ,   tup11Δ
+ normal GTPase activity
rhb1-K120R(aa) ,   rhb1-N153T(aa) ,   ryh1-Q70L(aa)
+ normal inositol hexakisphosphate kinase activity
asp1(1-385)(386-920 Δaa)[Overexpression] affecting activity of asp1
asp1(1-385)K341A(386-920,K341A aa)[Overexpression] affecting activity of asp1
asp1(1-385)R285A(386-920,R285A aa)[Overexpression] affecting activity of asp1
asp1-E248Q(aa) affecting activity of asp1
+ normal invertase activity during glucose starvation
ppk9Δ ,   scr1-S235A(aa) ,   scr1-S332A,S333A(aa) ,   scr1-S408A,S410A(aa) ,   scr1::ura4+[Null]
+ normal m7G(5')pppN diphosphatase activity
dcp2-F36A(aa) ,   dcp2-F44A(aa)
+ normal maltase activity
agl1-D287N(aa) ,   agl1-D676N(aa) ,   agl1-E484D(aa) ,   agl1-E714Q(aa)
+ normal mannosyltransferase activity
gpp74Δ affecting activity of och1
+ normal oleoyl-CoA ligase activity
lcf2Δ
+ normal palmitoyl-CoA ligase activity
lcf2Δ
+ normal peptidase activity
krp1-R102A(aa)[Overexpression] ,   krp1-R102K(aa) ,   krp1-R82A,R102A(aa) ,   krp1-R82A,R102K(aa)[Overexpression] ,   krp1-R82A(aa) ,   krp1-Y611*(612-709 Δaa)
sxa2-K309A(aa) affecting map2
sxa2-K309A,R310K(aa) affecting map2
+ normal peptide alpha-N-acetyltransferase activity
naa30-S24A(aa) ,   naa30-Y71F(aa)
+ normal peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity
ngl1ΔH1(1-15 Δaa)
+ normal peptide-serine-N-acetyltransferase activity
naa15-F533A,F536A(aa) affecting NatA complex
+ normal phosphatase activity
siw14-(79-287)(1-78 Δaa)[Overexpression]
clp1-6A-b(S396A,S408A,S467A,S468A,S493A,S513A aa) affecting clp1
+ normal poly(A)-specific ribonuclease activity
pabp-RRM4mut(F367A aa) affecting activity of ccr4
+ normal poly(U) polymerase activity
cid1-K144A(aa)
+ normal polyphosphatase activity
aps1-(11-210)(1-10 Δaa) affecting activity of aps1
aps1-(26-210)(1-25 Δaa) affecting activity of aps1
+ normal primary amine oxidase activity
cao1-H621A(aa) ,   ccc2Δ ,   ccs1Δ ,   cox17Δ
+ normal protein farnesyltransferase activity
cwg2-1(A202T aa)
+ normal protein kinase activity
cdc7-24(unknown) ,   cki1Δ298(299-446 Δaa) ,   cki2Δ351(352-435 Δaa)
atg101Δ affecting activity of atg1
atg11(522-583)(1-521,584-926 Δaa) affecting activity of atg1
atg13Δ affecting activity of atg1
atg17Δ affecting activity of atg1
cdc15-140(unknown) affecting activity of sid2
cdc16-116(R105C aa) affecting activity of cdc7 , plo1
cdc18+[Knockdown] affecting activity of cdc2
cdc18-C(1-141)(142-577 Δaa)[Overexpression] affecting activity of cdc2
cdc18-C(150-577)(1-149 Δaa)[Overexpression] affecting activity of cdc2
cdc18ΔCDK1-5(T4A,T10A,T46A,T60A,T101A,T104A,T134A aa)[Overexpression] affecting activity of cdc13
cdc2+[Overexpression] affecting activity of cdc2
cdc2-56(G183E aa) affecting activity of cdc2
cdk9ΔC(386-591 Δaa) affecting cdk9
cds1-T324V(aa) affecting cds1
cds1-T324V,S378A,S379A(aa) affecting cds1
cpc2+[Overexpression] affecting activity of pat1 affecting ste11
cpc2Δ affecting activity of pat1 affecting ste11
crb2(BRCT-778,S666A)(1-534,S666A aa)[Overexpression] affecting activity of rad3
csm1Δ affecting ark1
gad8-K263C(aa) affecting activity of gad8 affecting fkh2
gsk3-S335A(aa) affecting gsk3
hsk1-89(L339P,E403K,L416P aa) affecting activity of rad3 affecting mrc1
mcs4-D512N(aa) affecting activity of sty1
mei3-rxt(T30A aa) affecting activity of pka1 affecting mei3
mrc1-6A(S599A,S604A,S614A,T634A,S637A,T645A aa) affecting activity of hsk1 affecting mrc1
mre11-N122S(aa)[Knockdown] affecting activity of cds1
mre11-W215C(aa)[Knockdown] affecting activity of cds1
nim1(1-354)(355-593 Δaa) affecting cdr1
plo1-T14A(aa) affecting activity of plo1
pom1-6A(S427A,S428A,S437A,S439A,S441A,S442A,S443A,T482A,T484A,T486A,S488A,T1006A aa) affecting activity of pom1 affecting cdr2
rad3Δ affecting activity of hsk1 affecting mrc1
rgp1Δ affecting activity of tor1
ric1Δ affecting activity of tor1
ryh1Δ affecting activity of tor1
sfp1Δ affecting activity of tor2 affecting psk1
skb1Δ affecting activity of orb6 affecting orb6
spg1-B8(F127S aa) affecting activity of cdc7
wis1-AAA(S469A,S471A,T473A aa) affecting wis1
wis1-C458S(aa) affecting activity of wis1 affecting sty1
wis1-DD(S469D,T473D aa)[Overexpression] affecting sty1 modified residue Y173,T171
wis1ΔN300(1-300 Δaa) affecting sty1 modified residue Y173,T171
wos2+[Overexpression] affecting activity of cdc2
+ normal protein kinase activity during cellular response to hydroxyurea
bdf1Δ affecting activity of cds1
bdf2Δ affecting activity of cds1
hsk1-89(L339P,E403K,L416P aa) affecting activity of chk1
rad17-d14(R411W aa) affecting activity of cds1
rad17-K118E(aa) affecting activity of cds1
+ normal protein kinase activity during cellular response to methyl methanesulfonate
hst4-4SA(S354A,S355A,S362A,S363A aa) affecting activity of cds1
+ normal protein kinase activity during mitosis
cut12-1(R536*) affecting plo1
cut7-24(V968A aa) affecting plo1
nda3-KM311(G93E aa) affecting cdc2
rae1-1(G219E aa) affecting activity of cdc2
+ normal protein kinase activity during mitotic interphase
cdc25-22(C532Y aa) affecting activity of orb6
mto1Δ affecting nak1 , orb6
sid2-250(E314K aa) affecting nak1 , orb6
+ normal protein kinase activity during mitotic S phase during cellular response to DNA damage
rad51Δ affecting cds1
rqh1Δ affecting cds1
sfr1Δ affecting cds1
+ normal protein phosphatase activity
dis3-54(P509L aa) ,   ppa1::ura4+[Null] ,   pyp1ΔN234(1-234 Δaa)
dis2-T316A(aa) affecting activity of dis2
pyp2ΔN(1)(1-345 Δaa) affecting pyp2
+ normal pyridoxal kinase activity
plr1Δ
+ normal pyridoxamine-phosphate oxidase activity
plr1Δ
+ normal Rab geranylgeranyltransferase activity
cwg2-1(A202T aa)
+ normal RNA pyrophosphohydrolase activity
din1-K256A(aa) affecting din1
din1-W159A(aa) affecting din1
+ normal succinate dehydrogenase activity
pgr1+[Knockdown]
+ normal sulfite reductase activity
grx2Δ
+ normal superoxide dismutase activity
sod2-K25Q,K121Q,K126Q,K156Q,K175Q(aa) affecting sod2
sod2-K25R,K121R,K126R,K156R,K175R(aa) affecting sod2
+ normal tRNA methyltransferase activity
pka1Δ affecting pmt1
sck1Δ affecting pmt1
tor1Δ affecting pmt1
Multi-locus phenotype annotations for FYPO:0000660 and its descendants
Cell
Show details ...
Filters:
+ normal acid phosphatase activity
ctf1Δ erh1Δ ,   rhn1-R70A,K73A(aa) rpb1-CTD-S7A(aa) ,   rhn1-Y106A,R114A(aa) rpb1-CTD-S7A(aa) ,   rhn1Δ rpb1-CTD-S7A(aa)
aps1Δ duf89Δ rhn1Δ affecting activity of pho1
asp1(1-385)(386-920 Δaa) kcs1-R332T(aa) pet127-Asn8fs(T12TA) affecting activity of pho1
asp1(1-385)(386-920 Δaa) pqr1Δ affecting activity of pho1
asp1(1-492)(493-920 Δaa) plc1-P708L(aa) affecting activity of pho1
asp1(1-492)(493-920 Δaa) pqr1Δ affecting activity of pho1
asp1-D333A(aa) erh1Δ affecting activity of pho1
asp1-D333A(aa) seb1-G476S(aa) affecting activity of pho1
asp1-H397A(aa) snf22Δ affecting activity of pho1
asp1Δ seb1-G476S(aa) affecting activity of pho1
dis2Δ erh1Δ affecting activity of pho1
duf89Δ rhn1Δ rpb1-CTD-S7A(aa) affecting activity of pho1
erh1Δ ppn1Δ affecting activity of erh1
pho4Δ thi20-G271D(aa) affecting activity of pho1
pho4Δ tnr3-C545Y(aa) affecting activity of pho1
pqr1Δ rpb1-CTD-P6A(r2-r29-2)(aa) affecting activity of pho1
pqr1Δ rpb1-CTD-S5A(r2-r29)(aa) affecting activity of pho1
pqr1Δ rpb1-CTD-S7A(aa) affecting activity of pho1
+ normal alkaline phosphatase activity
cis4Δ zrg17Δ
+ normal DNA/DNA annealing activity
cut14-K38T(aa) cut3-K161I(aa)
+ normal protein kinase activity
dma1Δ plo1-25(unknown) affecting activity of cdc2
pck2Δ rho1+[Overexpression] affecting activity of pmk1
sfp1+[Overexpression] tor2-13(C2163R,I2280V,Q2305L aa) affecting activity of tor2 affecting psk1
+ normal protein kinase activity during cellular response to hydroxyurea
chk1Δ rad9-T412A(aa) affecting activity of cds1
+ normal protein kinase activity during mitosis
cdc7-A20(unknown) spg1-B8(F127S aa) affecting activity of plo1
+ normal protein kinase activity during mitotic interphase
cdc10-V50(H362Y aa) cdc13+[Knockdown] cig1Δ cig2Δ
cdc15-140(unknown) cdc25-22(C532Y aa) affecting activity of orb6
cdc16-116(R105C aa) cdc3-124(E43K aa) affecting activity of nak1
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